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South Carolina

$90+ Cheap flights from Buffalo (BUF) to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/17. Fares are subject to change and may not be available on all flights or dates of travel.
BUF — CHS
May 6 — May 131
Tue 5/6
Tue 5/13
1 adult, Economy
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Cheap flight deals from Buffalo to South Carolina

Keep the following information in mind while searching for Buffalo to South Carolina flight deals. Data was last updated May 1, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$180
(Frontier)

One-way from

$90
(Frontier)

Popular in

April

Cheapest in

September

Average price

$379
Provider with most accurate pricing for Buffalo-Myrtle Beach Intl flight deals.
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Provider most trusted by Cheapflights users for Buffalo-Myrtle Beach Intl flights.
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From Buffalo to South Carolina
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One-way flight from Buffalo to South Carolina
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Highest demand for flights based on searches. 8% potential increase in price ($34 potential increase over avg. RT price).
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Cheapest flight prices on average. 1% potential price decrease ($6 potential savings vs. average RT price).
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Average for round-trip flights in May 2025
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Find flight deals from Buffalo to South Carolina

Cheapest flights from Buffalo to South Carolina
Explore the most affordable flight options available from Buffalo to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 1, 2025.

This Frontier deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/169:51 amBUF - CLT
1 stop5h 40mFrontier
Sun 5/1810:36 pmCLT - BUF
1 stop10h 25mFrontier
Deal found 4/29$180
This JetBlue deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/106:00 amBUF - SAV
1 stop5h 40mJetBlue
Tue 6/1711:24 amSAV - BUF
1 stop7h 34mJetBlue
Deal found 4/29$185
This JetBlue deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/45:40 amBUF - CHS
1 stop4h 35mJetBlue
Wed 7/96:59 pmCHS - BUF
1 stop5h 00mJetBlue
Deal found 4/29$199
This American Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/303:54 pmBUF - SAV
1 stop5h 08mAmerican Airlines
Mon 6/28:24 pmSAV - BUF
1 stop3h 50mAmerican Airlines
Deal found 4/30$214
This American Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/247:11 pmBUF - CHS
1 stop5h 04mAmerican Airlines
Tue 5/276:34 amCHS - BUF
1 stop4h 42mAmerican Airlines
Deal found 4/29$218
This Delta deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/66:04 amBUF - HHH
1 stop5h 19mDelta
Tue 8/123:58 pmHHH - BUF
1 stop7h 03mDelta
Deal found 4/30$229
This Delta deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/2112:09 pmBUF - SAV
1 stop6h 42mDelta
Sat 8/306:30 pmSAV - BUF
1 stop5h 29mDelta
Deal found 4/30$229
This Delta deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/195:10 pmBUF - CHS
1 stop5h 43mDelta
Mon 6/235:15 amCHS - BUF
1 stop5h 50mDelta
Deal found 4/30$237
This Southwest deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/274:15 pmBUF - CHS
1 stop4h 00mSouthwest
Tue 6/36:30 amCHS - BUF
2 stops10h 35mSouthwest
Deal found 4/29$242
This American Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/126:01 amBUF - CLT
1 stop7h 32mAmerican Airlines
Mon 5/124:34 pmCLT - BUF
Nonstop1h 44mAmerican Airlines
Deal found 4/29$247
This Delta deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/410:50 amBUF - CAE
1 stop5h 28mDelta
Sun 6/81:24 pmCAE - BUF
1 stop5h 05mDelta
Deal found 4/30$249
This Delta deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/45:55 pmBUF - GSP
1 stop5h 11mDelta
Tue 6/106:58 pmGSP - BUF
1 stop4h 22mDelta
Deal found 4/30$257

Cheapflights Fare Finder

Customize your flight search to find flights from Buffalo to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 1, 2025.
Use the filters below to find and compare flights from Buffalo to South Carolina that are best for you.

Fly from

Buffalo

Fly to

South Carolina

Route

Depart

Return

Price

BuffaloCharlotte

BUF - CLT

BUFCLT

Buffalo

Fri 5/16

9:51 am-3:31 pm

1 stop5h 40m

Charlotte Douglas

Sun 5/18

10:36 pm-9:01 am

1 stop10h 25m

$180

BuffaloSavannah

BUF - SAV

BUFSAV

Buffalo

Tue 6/10

6:00 am-11:40 am

1 stop5h 40m

Savannah/Hilton Head

Tue 6/17

11:24 am-6:58 pm

1 stop7h 34m

$185

BuffaloCharleston

BUF - CHS

BUFCHS

Buffalo

Sat 6/21

5:40 am-10:15 am

1 stop4h 35m

Charleston

Sat 6/28

6:59 pm-11:59 pm

1 stop5h 00m

$201

BuffaloSavannah

BUF - SAV

BUFSAV

Buffalo

Fri 5/30

3:54 pm-9:02 pm

1 stop5h 08m

Savannah/Hilton Head

Mon 6/2

8:24 pm-12:14 am

1 stop3h 50m

$214

BuffaloCharleston

BUF - CHS

BUFCHS

Buffalo

Wed 5/28

6:10 am-10:45 am

1 stop4h 35m

Charleston

Wed 6/4

6:09 pm-12:14 am

1 stop6h 05m

$218

BuffaloHilton Head Island

BUF - HHH

BUFHHH

Buffalo

Wed 8/6

6:04 am-11:23 am

1 stop5h 19m

Hilton Head Island

Tue 8/12

3:58 pm-11:01 pm

1 stop7h 03m

$229

BuffaloSavannah

BUF - SAV

BUFSAV

Buffalo

Thu 8/21

12:09 pm-6:51 pm

1 stop6h 42m

Savannah/Hilton Head

Sat 8/30

6:30 pm-11:59 pm

1 stop5h 29m

$229

BuffaloCharleston

BUF - CHS

BUFCHS

Buffalo

Thu 6/19

5:10 pm-10:53 pm

1 stop5h 43m

Charleston

Mon 6/23

5:15 am-11:05 am

1 stop5h 50m

$237

BuffaloCharleston

BUF - CHS

BUFCHS

Buffalo

Wed 5/28

7:50 am-5:20 pm

2 stops9h 30m

Charleston

Wed 6/4

11:25 am-5:05 pm

1 stop5h 40m

$242

BuffaloCharlotte

BUF - CLT

BUFCLT

Buffalo

Mon 5/12

6:01 am-1:33 pm

1 stop7h 32m

Charlotte Douglas

Mon 5/12

4:34 pm-6:18 pm

Nonstop1h 44m

$247

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/29

Showing 1-10 of 52 results
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Best time to book a flight from Buffalo to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Buffalo with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Buffalo to South Carolina

What is the cheapest month to book a flight from Buffalo to South Carolina?

Currently, August is the cheapest month in which you can book a flight from Buffalo to South Carolina (average of $217). Flying from Buffalo to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from BUF to SC?

Find hourly flight availability from Buffalo to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated May 1, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Buffalo to South Carolina as you normally would.

Rainfall in South Carolina by month

Plan your trip to South Carolina by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in South Carolina ranges from 3.0 - 6.5 inches per month. July is typically the wettest month, when rainfall can reach 6.5 in. November is typically the driest time to visit South Carolina when rainfall is around 3.0 in.

Temperature in South Carolina by month

Plan your trip to South Carolina by taking into account the average temperature totals by month.

If weather is an important factor for your trip to South Carolina, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 44.6 F).

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated May 1, 2025.
Read through reviews of airlines operating flights from Buffalo to South Carolina, such as Southwest, Delta and United Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,294 reviews

Boarding

8.2

Comfort

8.0

Food

7.1

Entertainment

7.6

Crew

8.6

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Gina,Apr 2025

LAS - DEN

Good, the crew was friendly and helpful. The pilot had great skills in keeping the plane stable through rough turbulence. Smooth landing, too! Thank you!
Southwest
8.0
Very good
4,294 reviews
Southwest
8.0
Very good
4,294 reviews

Boarding

8.2

Comfort

8.0

Food

7.1

Entertainment

7.6

Crew

8.6

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Gina,Apr 2025

LAS - DEN

Good, the crew was friendly and helpful. The pilot had great skills in keeping the plane stable through rough turbulence. Smooth landing, too! Thank you!
Delta
8.0
Very good
7,934 reviews
Southwest
8.0
Very good
4,294 reviews

Boarding

8.2

Comfort

8.0

Food

7.1

Entertainment

7.6

Crew

8.6

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Gina,Apr 2025

LAS - DEN

Good, the crew was friendly and helpful. The pilot had great skills in keeping the plane stable through rough turbulence. Smooth landing, too! Thank you!
United Airlines
7.4
Good
8,696 reviews
Southwest
8.0
Very good
4,294 reviews

Boarding

8.2

Comfort

8.0

Food

7.1

Entertainment

7.6

Crew

8.6

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Gina,Apr 2025

LAS - DEN

Good, the crew was friendly and helpful. The pilot had great skills in keeping the plane stable through rough turbulence. Smooth landing, too! Thank you!
JetBlue
7.3
Good
2,922 reviews
Southwest
8.0
Very good
4,294 reviews

Boarding

8.2

Comfort

8.0

Food

7.1

Entertainment

7.6

Crew

8.6

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Gina,Apr 2025

LAS - DEN

Good, the crew was friendly and helpful. The pilot had great skills in keeping the plane stable through rough turbulence. Smooth landing, too! Thank you!
American Airlines
7.2
Good
10,000 reviews
Southwest
8.0
Very good
4,294 reviews

Boarding

8.2

Comfort

8.0

Food

7.1

Entertainment

7.6

Crew

8.6

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Gina,Apr 2025

LAS - DEN

Good, the crew was friendly and helpful. The pilot had great skills in keeping the plane stable through rough turbulence. Smooth landing, too! Thank you!

Related info for your journey

Find useful and relevant information for your journey from Buffalo to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Buffalo to South Carolina?

    Buffalo (BUF) is the airport you will fly out of if you book a flight from Buffalo to South Carolina. It is only a 8.3 mi journey to Buffalo (BUF) from Buffalo’s city center.

  • What are the cheapest airlines to fly from Buffalo to South Carolina one-way?

    The cheapest airlines for a one-way flight from Buffalo to South Carolina are Frontier ($90), American Airlines ($115), and United Airlines ($119).

  • What are the most popular routes from Buffalo to South Carolina?

    While some choose either Buffalo - Myrtle Beach Intl or Buffalo - Charleston, Buffalo - Charlotte Douglas is the most popular route from Buffalo to South Carolina.

  • Can I find deals for flights from Buffalo to South Carolina that include hotel bookings?

    Yes. In addition to deals on Buffalo to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Buffalo to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Buffalo to South Carolina.

  • Can I find deals for business class flights from Buffalo to South Carolina?

    Yes. Cheapflights offers flight deals from Buffalo to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Buffalo to South Carolina?

    Currently, August is the cheapest month in which you can book a flight from Buffalo to South Carolina (average of $217). Flying from Buffalo to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Buffalo to South Carolina

See prices for flight routes from nearby airports that may be better suited for you.
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Top 5 airlines flying from Buffalo to South Carolina

Discover the top 5 airlines that operate flights from Buffalo to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 1, 2025.
AirlineCheapestAverageFlexibilityOn-time
JetBlueCheapest$191Average$273FlexibilityNo cancel feeOn-time62%
American AirlinesCheapest$196Average$393FlexibilityNo cancel feeOn-time71%
DeltaCheapest$198Average$326FlexibilityNo cancel feeOn-timeN/A
SouthwestCheapest$218Average$410FlexibilityNo cancel feeOn-time63%
United AirlinesCheapest$234Average$381FlexibilityNo cancel feeOn-time69%

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