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South Carolina

$81+ Cheap flights from Buffalo (BUF) to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/8. Fares are subject to change and may not be available on all flights or dates of travel.
BUF — CHS
Jun 17 — Jun 241
Tue 6/17
Tue 6/24
1 adult, Economy
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Cheap flight deals from Buffalo to South Carolina

Keep the following information in mind while searching for Buffalo to South Carolina flight deals. Data was last updated June 12, 2025.

Round-trip from

$161
(JetBlue)

One-way from

$81
(JetBlue)

Popular in

April

Cheapest in

September

Average price

$346
From Buffalo to South Carolina
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One-way flight from Buffalo to South Carolina
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Highest demand for flights based on searches. 7% potential increase in price ($31 potential increase over avg. RT price).
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Cheapest flight prices on average. 1% potential price decrease ($6 potential savings vs. average RT price).
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Average for round-trip flights in June 2025
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Find flight deals from Buffalo to South Carolina

Cheapest flights from Buffalo to South Carolina
Explore the most affordable flight options available from Buffalo to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 12, 2025.

This JetBlue deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/85:35 amBUF - CHS
1 stop4h 40mJetBlue
Tue 7/156:59 pmCHS - BUF
1 stop5h 00mJetBlue
Deal found 6/9$161
This American Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/147:38 pmBUF - MYR
1 stop4h 07mAmerican Airlines
Mon 8/181:12 pmMYR - BUF
1 stop4h 29mAmerican Airlines
Deal found 6/11$217
This American Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/62:34 pmBUF - CHS
1 stop4h 29mAmerican Airlines
Wed 8/135:33 pmCHS - BUF
1 stop4h 07mAmerican Airlines
Deal found 6/11$217
This United Airlines deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/46:00 amBUF - CHS
1 stop4h 07mUnited Airlines
Thu 9/116:05 amCHS - BUF
2 stops8h 01mUnited Airlines
Deal found 6/12$222
This Delta deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/146:20 amBUF - MYR
1 stop4h 16mDelta
Sat 8/236:35 pmMYR - BUF
1 stop4h 24mDelta
Deal found 6/10$233
This Southwest deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/165:50 amBUF - CLT
1 stop4h 15mSouthwest
Tue 9/237:40 amCLT - BUF
1 stop4h 20mSouthwest
Deal found 6/9$242
This American Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/16:10 amBUF - CAE
1 stop4h 05mAmerican Airlines
Mon 11/36:02 amCAE - BUF
1 stop5h 49mAmerican Airlines
Deal found 6/11$249
This JetBlue deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/112:45 pmBUF - SAV
1 stop6h 44mJetBlue
Mon 11/310:44 amSAV - BUF
1 stop8h 37mJetBlue
Deal found 6/11$249
This Delta deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/66:04 amBUF - HHH
1 stop5h 27mDelta
Wed 9/104:02 pmHHH - BUF
1 stop7h 22mDelta
Deal found 6/10$249
This Delta deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/302:19 pmBUF - CLT
1 stop4h 57mDelta
Tue 9/29:00 amCLT - BUF
1 stop4h 41mDelta
Deal found 6/11$251
This American Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/3011:54 amBUF - CLT
Nonstop1h 56mAmerican Airlines
Sat 9/67:59 pmCLT - BUF
Nonstop1h 54mAmerican Airlines
Deal found 6/11$253
This Southwest deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/63:25 pmBUF - MYR
1 stop4h 00mSouthwest
Sat 9/136:10 amMYR - BUF
2 stops10h 05mSouthwest
Deal found 6/10$254

Cheapflights Fare Finder

Customize your flight search to find flights from Buffalo to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 12, 2025.
Use the filters below to find and compare flights from Buffalo to South Carolina that are best for you.

Fly from

Buffalo

Fly to

South Carolina

Route

Depart

Return

Price

BuffaloCharleston

BUF - CHS

BUFCHS

Buffalo

Tue 7/8

5:35 am-10:15 am

1 stop4h 40m

Charleston

Tue 7/15

6:59 pm-11:59 pm

1 stop5h 00m

$161

BuffaloMyrtle Beach

BUF - MYR

BUFMYR

Buffalo

Thu 8/14

7:38 pm-11:45 pm

1 stop4h 07m

Myrtle Beach Intl

Mon 8/18

1:12 pm-5:41 pm

1 stop4h 29m

$217

BuffaloCharleston

BUF - CHS

BUFCHS

Buffalo

Wed 8/6

2:34 pm-7:03 pm

1 stop4h 29m

Charleston

Wed 8/13

5:33 pm-9:40 pm

1 stop4h 07m

$217

BuffaloMyrtle Beach

BUF - MYR

BUFMYR

Buffalo

Thu 8/14

6:20 am-10:36 am

1 stop4h 16m

Myrtle Beach Intl

Sat 8/23

6:35 pm-10:59 pm

1 stop4h 24m

$233

BuffaloSavannah

BUF - SAV

BUFSAV

Buffalo

Sat 11/1

12:45 pm-7:29 pm

1 stop6h 44m

Savannah/Hilton Head

Mon 11/3

10:44 am-7:21 pm

1 stop8h 37m

$249

BuffaloHilton Head Island

BUF - HHH

BUFHHH

Buffalo

Sat 9/6

6:04 am-11:31 am

1 stop5h 27m

Hilton Head Island

Wed 9/10

4:02 pm-11:24 pm

1 stop7h 22m

$249

BuffaloCharlotte

BUF - CLT

BUFCLT

Buffalo

Sat 8/30

2:19 pm-7:16 pm

1 stop4h 57m

Charlotte Douglas

Tue 9/2

9:00 am-1:41 pm

1 stop4h 41m

$251

BuffaloCharlotte

BUF - CLT

BUFCLT

Buffalo

Sat 8/30

11:54 am-1:50 pm

Nonstop1h 56m

Charlotte Douglas

Tue 9/2

10:23 am-12:04 pm

Nonstop1h 41m

$253

BuffaloMyrtle Beach

BUF - MYR

BUFMYR

Buffalo

Sat 9/6

3:25 pm-7:25 pm

1 stop4h 00m

Myrtle Beach Intl

Sat 9/13

6:10 am-4:15 pm

2 stops10h 05m

$254

BuffaloGreenville

BUF - GSP

BUFGSP

Buffalo

Tue 9/23

6:00 am-1:08 pm

1 stop7h 08m

Greenville

Thu 10/2

6:05 pm-10:57 pm

1 stop4h 52m

$257

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/10

Showing 1-10 of 59 results
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Best time to book a flight from Buffalo to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Buffalo with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Buffalo to South Carolina

What is the cheapest month to book a flight from Buffalo to South Carolina?

Currently, August is the cheapest month in which you can book a flight from Buffalo to South Carolina (average of $217). Flying from Buffalo to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from BUF to SC?

Find hourly flight availability from Buffalo to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated June 12, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Buffalo to South Carolina as you normally would.

Rainfall in South Carolina by month

Plan your trip to South Carolina by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in South Carolina ranges from 3.0 - 6.5 inches per month. July is typically the wettest month, when rainfall can reach 6.5 in. November is typically the driest time to visit South Carolina when rainfall is around 3.0 in.

Temperature in South Carolina by month

Plan your trip to South Carolina by taking into account the average temperature totals by month.

If weather is an important factor for your trip to South Carolina, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 44.6 F).

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated June 12, 2025.
Read through reviews of airlines operating flights from Buffalo to South Carolina, such as Southwest, Delta and United Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,287 reviews

Food

7.1

Boarding

8.2

Entertainment

7.6

Overall

8.0

Comfort

8.0

Crew

8.6

Reviews

1 / 20
8.0
Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.
Southwest
8.0
Very good
4,287 reviews
Southwest
8.0
Very good
4,287 reviews

Food

7.1

Boarding

8.2

Entertainment

7.6

Overall

8.0

Comfort

8.0

Crew

8.6

Reviews

1 / 20
8.0
Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.
Delta
8.0
Very good
7,950 reviews
Southwest
8.0
Very good
4,287 reviews

Food

7.1

Boarding

8.2

Entertainment

7.6

Overall

8.0

Comfort

8.0

Crew

8.6

Reviews

1 / 20
8.0
Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.
United Airlines
7.4
Good
8,790 reviews
Southwest
8.0
Very good
4,287 reviews

Food

7.1

Boarding

8.2

Entertainment

7.6

Overall

8.0

Comfort

8.0

Crew

8.6

Reviews

1 / 20
8.0
Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.
JetBlue
7.3
Good
2,925 reviews
Southwest
8.0
Very good
4,287 reviews

Food

7.1

Boarding

8.2

Entertainment

7.6

Overall

8.0

Comfort

8.0

Crew

8.6

Reviews

1 / 20
8.0
Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.
American Airlines
7.2
Good
10,000 reviews
Southwest
8.0
Very good
4,287 reviews

Food

7.1

Boarding

8.2

Entertainment

7.6

Overall

8.0

Comfort

8.0

Crew

8.6

Reviews

1 / 20
8.0
Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.

Related info for your journey

Find useful and relevant information for your journey from Buffalo to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Buffalo to South Carolina?

    Buffalo (BUF) is the airport you will fly out of if you book a flight from Buffalo to South Carolina. It is only a 8.3 mi journey to Buffalo (BUF) from Buffalo’s city center.

  • What are the cheapest airlines to fly from Buffalo to South Carolina one-way?

    The cheapest airlines for a one-way flight from Buffalo to South Carolina are JetBlue ($81), Southwest ($100), and American Airlines ($109).

  • What are the most popular routes from Buffalo to South Carolina?

    While some choose either Buffalo - Myrtle Beach Intl or Buffalo - Charleston, Buffalo - Charlotte Douglas is the most popular route from Buffalo to South Carolina.

  • Can I find deals for flights from Buffalo to South Carolina that include hotel bookings?

    Yes. In addition to deals on Buffalo to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Buffalo to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Buffalo to South Carolina.

  • Can I find deals for business class flights from Buffalo to South Carolina?

    Yes. Cheapflights offers flight deals from Buffalo to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Buffalo to South Carolina?

    Currently, August is the cheapest month in which you can book a flight from Buffalo to South Carolina (average of $217). Flying from Buffalo to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Buffalo to South Carolina

See prices for flight routes from nearby airports that may be better suited for you.
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Top 5 airlines flying from Buffalo to South Carolina

Discover the top 5 airlines that operate flights from Buffalo to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 12, 2025.
AirlineCheapestAverageFlexibilityOn-time
JetBlueCheapest$191Average$246FlexibilityNo cancel feeOn-time62%
American AirlinesCheapest$196Average$386FlexibilityNo cancel feeOn-time71%
DeltaCheapest$196Average$316FlexibilityNo cancel feeOn-timeN/A
SouthwestCheapest$218Average$408FlexibilityNo cancel feeOn-time63%
United AirlinesCheapest$254Average$368FlexibilityNo cancel feeOn-time69%

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