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Sioux Falls

$259+ Cheap flights from Knoxville to Sioux Falls (TYS - FSD)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/13. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — FSD
Apr 9 — Apr 161
Thu 4/9
Thu 4/16
1 adult, Economy
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Cheap flight deals from Knoxville to Sioux Falls

Cheapest flights from Knoxville to Sioux Falls
Explore the most affordable flight options available from Knoxville to Sioux Falls. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 10, 2026.

This United Airlines deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/267:00 am
TYS
-
FSD
1 stop4h 46m
United Airlines
Tue 3/316:00 am
FSD
-
TYS
1 stop8h 06m
United Airlines
Deal found 3/6$294
This American Airlines deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/269:25 am
TYS
-
FSD
2 stops10h 45m
American Airlines
Tue 3/312:06 pm
FSD
-
TYS
1 stop6h 18m
American Airlines
Deal found 3/6$299
This Kiwi.com deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/111:59 pm
TYS
-
FSD
1 stop20h 36m
Allegiant Air
Fri 4/176:11 pm
FSD
-
TYS
1 stop16h 55m
Allegiant Air
Deal found 3/5$312
This United Airlines deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/267:00 am
TYS
-
FSD
1 stop4h 46m
United Airlines
Sun 3/293:10 pm
FSD
-
TYS
1 stop6h 19m
United Airlines
Deal found 3/5$314
This Kiwi.com deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/111:59 pm
TYS
-
FSD
1 stop20h 36m
Allegiant Air
Sun 4/1911:35 am
FSD
-
TYS
1 stop28h 14m
Allegiant Air
Deal found 3/5$321
This Kiwi.com deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/95:10 pm
TYS
-
FSD
1 stop25h 11m
Allegiant Air
Sun 4/1911:35 am
FSD
-
TYS
1 stop28h 14m
Allegiant Air
Deal found 3/5$323
This Delta deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/86:35 am
TYS
-
FSD
1 stop7h 18m
Delta
Sat 4/184:17 pm
FSD
-
TYS
1 stop5h 42m
Delta
Deal found 3/5$324
This Delta deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/85:40 am
TYS
-
FSD
2 stops8h 13m
Delta
Sun 4/195:25 am
FSD
-
TYS
1 stop4h 52m
Delta
Deal found 3/5$329
This American Airlines deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/254:29 pm
TYS
-
FSD
1 stop6h 11m
American Airlines
Sat 3/285:21 pm
FSD
-
TYS
1 stop5h 30m
American Airlines
Deal found 3/5$351
This Kiwi.com deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/125:10 pm
TYS
-
FSD
1 stop25h 11m
Allegiant Air
Fri 4/176:11 pm
FSD
-
TYS
1 stop16h 55m
Allegiant Air
Deal found 3/5$352

Find flight deals from Knoxville to Sioux Falls

Discover tips and strategies to find the most affordable flight options for your journey from Knoxville (TYS) to Sioux Falls (FSD). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated March 10, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$294
(United Airlines)

One-way from

$259
(Delta)

Popular in

June

Cheapest in

April
Provider with most accurate pricing for Knoxville McGhee Tyson-Sioux Falls Joe Foss Field flight deals.
Search Deals
Provider most trusted by Cheapflights users for Knoxville McGhee Tyson-Sioux Falls Joe Foss Field flights.
Search Deals
From Knoxville McGhee Tyson to Sioux Falls Joe Foss Field
Search Deals
One-way flight from Knoxville McGhee Tyson to Sioux Falls Joe Foss Field
Search Deals
Highest demand for flights based on searches. 20% potential increase in price ($106 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 6% potential price decrease ($24 potential savings vs. average RT price).
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Knoxville to Sioux Falls that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 10, 2026.
Use the filters below to find and compare flights from Knoxville to Sioux Falls that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

KnoxvilleSioux Falls

TYS - FSD

TYSFSD

Knoxville McGhee Tyson

Fri 4/10

5:10 pm-10:12 pm

1 stop6h 02m

Sioux Falls Joe Foss Field

Sat 4/18

4:17 pm-10:59 pm

1 stop5h 42m

$324

KnoxvilleSioux Falls

TYS - FSD

TYSFSD

Knoxville McGhee Tyson

Wed 4/15

7:00 am-10:42 am

1 stop4h 42m

Sioux Falls Joe Foss Field

Sat 4/18

1:43 pm-10:29 pm

1 stop7h 46m

$359

KnoxvilleSioux Falls

TYS - FSD

TYSFSD

Knoxville McGhee Tyson

Fri 4/10

5:10 pm-11:04 pm

2 stops6h 54m

Sioux Falls Joe Foss Field

Sun 4/19

5:25 am-11:17 am

1 stop4h 52m

$364

KnoxvilleSioux Falls

TYS - FSD

TYSFSD

Knoxville McGhee Tyson

Tue 3/24

5:05 am-12:37 pm

1 stop8h 32m

Sioux Falls Joe Foss Field

Sat 3/28

2:07 pm-11:50 pm

2 stops8h 43m

$382

KnoxvilleSioux Falls

TYS - FSD

TYSFSD

Knoxville McGhee Tyson

Wed 3/25

9:25 am-7:10 pm

2 stops10h 45m

Sioux Falls Joe Foss Field

Sat 3/28

1:26 pm-11:50 pm

2 stops9h 24m

$387
Cheapest one-way

KnoxvilleSioux Falls

TYS - FSD

TYSFSD

Knoxville McGhee Tyson

Wed 5/13

3:30 pm-7:49 pm

1 stop5h 19m

$259

KnoxvilleSioux Falls

TYS - FSD

TYSFSD

Knoxville McGhee Tyson

Wed 5/13

4:09 pm-9:54 pm

1 stop6h 45m

$259
Quickest one-way

KnoxvilleSioux Falls

TYS - FSD

TYSFSD

Knoxville McGhee Tyson

Wed 5/13

5:55 pm-9:52 pm

1 stop4h 57m

$300

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/7

Sorted by cheapest first

Compare providers for flights from Knoxville to Sioux Falls

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Knoxville to Sioux Falls in March.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Knoxville-Sioux Falls flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Knoxville-Sioux Falls flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Knoxville-Sioux Falls flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Knoxville-Sioux Falls flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Knoxville-Sioux Falls flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Knoxville to Sioux Falls

Have a flexible travel schedule? Discover the best time to fly to Sioux Falls from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Reviews of airlines servicing Sioux Falls

Get insights into the airlines that provide service to Sioux Falls. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Sioux Falls. Reviews last updated March 10, 2026.
Get a feel of what it's like to fly with United Airlines and American Airlines from Knoxville to Sioux Falls by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
United Airlines
7.4
Good
9,409 reviews

Crew

8.1

Food

6.6

Overall

7.4

Comfort

7.3

Boarding

7.7

Entertainment

7.1

Reviews

1 / 20
10.0
Excellent

Dane,Jan 2026

TYS - IAD

It was a short flight, so no time for amenities. Just glad everything was quick and easy from boarding to arriving at my destination with my family
United Airlines
7.4
Good
9,409 reviews
United Airlines
7.4
Good
9,409 reviews

Crew

8.1

Food

6.6

Overall

7.4

Comfort

7.3

Boarding

7.7

Entertainment

7.1

Reviews

1 / 20
10.0
Excellent

Dane,Jan 2026

TYS - IAD

It was a short flight, so no time for amenities. Just glad everything was quick and easy from boarding to arriving at my destination with my family
American Airlines
7.1
Good
11,413 reviews
United Airlines
7.4
Good
9,409 reviews

Crew

8.1

Food

6.6

Overall

7.4

Comfort

7.3

Boarding

7.7

Entertainment

7.1

Reviews

1 / 20
10.0
Excellent

Dane,Jan 2026

TYS - IAD

It was a short flight, so no time for amenities. Just glad everything was quick and easy from boarding to arriving at my destination with my family

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Sioux Falls. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Knoxville to Sioux Falls?

    Departing from Knoxville to Sioux Falls will take you 4h 42m. The distance from Knoxville to Sioux Falls is about 863 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines flying from Knoxville to Sioux Falls round-trip?

    Flying on American Airlines is currently your cheapest option to Sioux Falls, with prices starting at $248. Another option worth looking into is United Airlines, starting at $269 round trip. Users have found that American Airlines is 38% cheaper than the other options available to this destination.

  • Can I find deals for flights from Knoxville to Sioux Falls that include hotel bookings?

    Yes. In addition to deals on Knoxville to Sioux Falls flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Sioux Falls?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Sioux Falls.

  • Can I find deals for business class flights from Knoxville to Sioux Falls?

    Yes. Cheapflights offers flight deals from Knoxville to Sioux Falls by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near Sioux Falls?

Book flights to Sioux Falls if you plan to visit one of these locations
Marshall

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Top 2 airlines flying from Knoxville to Sioux Falls

Discover the top 2 airlines that operate flights from Knoxville to Sioux Falls. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 10, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$248Average$470FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$269Average$408FlexibilityNo cancel feeOn-time69%

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