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Sioux Falls

$249+ Cheap flights from Knoxville to Sioux Falls (TYS - FSD)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/3. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — FSD
jun. 17 — jun. 241
mar. 6/17
mar. 6/24
1 adult, Economy
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Cheap flight deals from Knoxville to Sioux Falls

Discover tips and strategies to find the most affordable flight options for your journey from Knoxville (TYS) to Sioux Falls (FSD). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated junio 12, 2025.

Round-trip from

$249
(American Airlines)

Popular in

June

Cheapest in

January

Average price

$636
From Knoxville McGhee Tyson to Sioux Falls Joe Foss Field
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Highest demand for flights based on searches. 4% potential increase in price ($20 potential increase over avg. RT price).
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Cheapest flight prices on average. 5% potential price decrease ($22 potential savings vs. average RT price).
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Average for round-trip flights in June 2025
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Find flight deals from Knoxville to Sioux Falls

Cheapest flights from Knoxville to Sioux Falls
Explore the most affordable flight options available from Knoxville to Sioux Falls. Find the lowest fares from popular airlines and budget airlines, with prices last updated on junio 12, 2025.

This American Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 10/34:37 pmTYS - FSD
1 stop5h 46mAmerican Airlines
dom. 10/57:00 amFSD - TYS
1 stop4h 21mAmerican Airlines
Deal found 6/11$249
This Mytrip deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 7/159:00 amTYS - FSD
1 stop25h 47mAllegiant Air
vie. 7/188:06 pmFSD - TYS
2 stops25h 41mAllegiant Air
Deal found 6/11$301
This Mytrip deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 7/116:55 amTYS - FSD
2 stops33h 52mMultiple Airlines
sáb. 7/126:55 pmFSD - TYS
1 stop27h 01mMultiple Airlines
Deal found 6/11$323
This United Airlines deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 7/210:55 amTYS - FSD
2 stops10h 25mUnited Airlines
mié. 7/93:10 pmFSD - TYS
1 stop6h 25mUnited Airlines
Deal found 6/12$390
This Delta deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 7/156:42 amTYS - FSD
1 stop6h 39mDelta
vie. 7/1811:12 amFSD - TYS
1 stop4h 20mDelta
Deal found 6/11$448

Cheapflights Fare Finder

Customize your flight search to find flights from Knoxville to Sioux Falls that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated junio 12, 2025.
Use the filters below to find and compare flights from Knoxville to Sioux Falls that are best for you.

Fly from

Knoxville

Fly to

Sioux Falls

Route

Depart

Return

Price

KnoxvilleSioux Falls

TYS - FSD

TYSFSD

Knoxville McGhee Tyson

mar. 9/2

2:23 pm-9:03 pm

1 stop7h 40m

Sioux Falls Joe Foss Field

sáb. 9/6

5:33 pm-12:21 am

1 stop5h 48m

$260

KnoxvilleSioux Falls

TYS - FSD

TYSFSD

Knoxville McGhee Tyson

mar. 7/15

9:00 am-9:47 am

1 stop25h 47m

Sioux Falls Joe Foss Field

vie. 7/18

8:06 pm-10:47 pm

2 stops25h 41m

$301

KnoxvilleSioux Falls

TYS - FSD

TYSFSD

Knoxville McGhee Tyson

vie. 7/11

6:55 am-3:47 pm

2 stops33h 52m

Sioux Falls Joe Foss Field

sáb. 7/12

6:55 pm-10:56 pm

1 stop27h 01m

$323

KnoxvilleSioux Falls

TYS - FSD

TYSFSD

Knoxville McGhee Tyson

mié. 7/2

10:55 am-8:20 pm

2 stops10h 25m

Sioux Falls Joe Foss Field

mié. 7/9

3:10 pm-10:35 pm

1 stop6h 25m

$390

KnoxvilleSioux Falls

TYS - FSD

TYSFSD

Knoxville McGhee Tyson

mar. 7/15

6:42 am-12:21 pm

1 stop6h 39m

Sioux Falls Joe Foss Field

vie. 7/18

11:12 am-4:32 pm

1 stop4h 20m

$448

KnoxvilleSioux Falls

TYS - FSD

TYSFSD

Knoxville McGhee Tyson

vie. 6/20

5:37 pm-1:35 pm

2 stops20h 58m

$264

KnoxvilleSioux Falls

TYS - FSD

TYSFSD

Knoxville McGhee Tyson

vie. 6/20

5:15 am-12:34 pm

1 stop8h 19m

$270

KnoxvilleSioux Falls

TYS - FSD

TYSFSD

Knoxville McGhee Tyson

vie. 6/20

6:00 am-3:49 pm

3 stops34h 49m

$379

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/10

Best time to book a flight from Knoxville to Sioux Falls

Have a flexible travel schedule? Discover the best time to fly to Sioux Falls from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to Sioux Falls

What is the cheapest month to book a flight from Knoxville to Sioux Falls?

Currently, September is the cheapest month in which you can book a flight from Knoxville to Sioux Falls (average of $334). Flying from Knoxville to Sioux Falls in December is currently the most expensive (average of $446). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from TYS to FSD?

Find hourly flight availability from Knoxville to Sioux Falls. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated junio 12, 2025.

One of the essential ways to save on airfare from Knoxville to Sioux Falls is to remain as flexible as possible. Flights that are at noon tend to be the most expensive. A flight in the morning could potentially save you up to 24% on airfare.

Rainfall in Sioux Falls by month

Plan your trip to Sioux Falls by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Sioux Falls ranges from 0.6 - 3.9 inches per month. June is typically the wettest month, when rainfall can reach 3.9 in. January is typically the driest time to visit Sioux Falls when rainfall is around 0.6 in.

Temperature in Sioux Falls by month

Plan your trip to Sioux Falls by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Sioux Falls, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 73.4 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 15.8 F).

Reviews of airlines servicing Sioux Falls

Get insights into the airlines that provide service to Sioux Falls. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Sioux Falls. Reviews last updated junio 12, 2025.
See what other customers who have flown with Delta, United Airlines and Allegiant Air from Knoxville to Sioux Falls have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,946 reviews

Crew

8.5

Overall

8.0

Boarding

8.2

Comfort

7.9

Food

7.3

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,946 reviews
Delta
8.0
Very good
7,946 reviews

Crew

8.5

Overall

8.0

Boarding

8.2

Comfort

7.9

Food

7.3

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
United Airlines
7.4
Good
8,790 reviews
Delta
8.0
Very good
7,946 reviews

Crew

8.5

Overall

8.0

Boarding

8.2

Comfort

7.9

Food

7.3

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Allegiant Air
7.3
Good
725 reviews
Delta
8.0
Very good
7,946 reviews

Crew

8.5

Overall

8.0

Boarding

8.2

Comfort

7.9

Food

7.3

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,946 reviews

Crew

8.5

Overall

8.0

Boarding

8.2

Comfort

7.9

Food

7.3

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Sioux Falls. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines flying from Knoxville to Sioux Falls round-trip?

    Flying on American Airlines is currently your cheapest option to Sioux Falls, with prices starting at $249. Additional round-trip tickets that might be worth considering are offered by Allegiant Air and United Airlines, with the lowest prices starting at $301 and $390, respectively. Users have found that American Airlines is 43% cheaper than the other options available to this destination.

  • Can I find deals for flights from Knoxville to Sioux Falls that include hotel bookings?

    Yes. In addition to deals on Knoxville to Sioux Falls flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Sioux Falls?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Sioux Falls.

  • Can I find deals for business class flights from Knoxville to Sioux Falls?

    Yes. Cheapflights offers flight deals from Knoxville to Sioux Falls by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Knoxville to Sioux Falls?

    Currently, September is the cheapest month in which you can book a flight from Knoxville to Sioux Falls (average of $334). Flying from Knoxville to Sioux Falls in December is currently the most expensive (average of $446). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Top 2 airlines flying from Knoxville to Sioux Falls

Discover the top 2 airlines that operate flights from Knoxville to Sioux Falls. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated junio 12, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$258Average$568FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$357Average$538FlexibilityNo cancel feeOn-time69%

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