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Sicily

$286+ Cheap flights from Indiana to Sicily

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/27. Fares are subject to change and may not be available on all flights or dates of travel.
IND — CTA
Jan 14 — Jan 211
Wed 1/14
Wed 1/21
1 adult, Economy
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Cheap flight deals from Indiana to Sicily

Cheapest flights from Indiana to Sicily
Explore the most affordable flight options available from Indiana to Sicily. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 15, 2025.

This Mytrip deal was found by Cheapflights users on 12/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/309:50 pmORD - CTA
2 stops17h 50mMultiple Airlines
Sat 1/105:45 amCTA - ORD
3 stops20h 46mMultiple Airlines
Deal found 12/12$679
This oojo deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/3011:50 amORD - CTA
1 stop13h 45mTurkish Airlines
Sat 1/109:35 amCTA - ORD
1 stop15h 50mTurkish Airlines
Deal found 12/14$1,138
This FlightHub deal was found by Cheapflights users on 12/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/2711:50 amORD - PMO
1 stop22h 55mTurkish Airlines
Wed 12/316:45 pmPMO - ORD
1 stop22h 20mTurkish Airlines
Deal found 12/13$1,428
This Kiwi.com deal was found by Cheapflights users on 12/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/285:40 pmORD - PMO
1 stop16h 45mMultiple Airlines
Wed 12/319:15 amPMO - ORD
2 stops17h 45mMultiple Airlines
Deal found 12/13$1,656
This KAYAK deal was found by Cheapflights users on 12/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/2711:50 amORD - PMO
2 stops19h 10mMultiple Airlines
Wed 12/316:45 pmPMO - ORD
1 stop22h 20mMultiple Airlines
Deal found 12/13$1,687
This ITA Airways deal was found by Cheapflights users on 12/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure ITA Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/289:20 amORD - PMO
2 stops30h 40mITA Airways
Wed 12/316:10 amPMO - ORD
2 stops19h 09mITA Airways
Deal found 12/13$1,751
This FlightHub deal was found by Cheapflights users on 12/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/2711:50 amORD - PMO
1 stop22h 55mTurkish Airlines
Fri 1/29:30 amPMO - ORD
1 stop15h 55mTurkish Airlines
Deal found 12/13$1,757
This oojo deal was found by Cheapflights users on 12/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/1311:50 amORD - PMO
1 stop22h 55mTurkish Airlines
Mon 12/299:30 amPMO - ORD
1 stop31h 35mTurkish Airlines
Deal found 12/13$1,766
This FlightHub deal was found by Cheapflights users on 12/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/264:20 pmORD - PMO
1 stop12h 05mMultiple Airlines
Wed 12/319:10 amPMO - ORD
1 stop14h 10mMultiple Airlines
Deal found 12/13$1,777
This FlightHub deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/1811:50 amORD - CTA
1 stop23h 35mTurkish Airlines
Sat 12/209:35 amCTA - ORD
1 stop55h 30mTurkish Airlines
Deal found 12/14$1,778
This FlightHub deal was found by Cheapflights users on 12/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/269:20 amORD - PMO
2 stops18h 05mITA Airways
Wed 12/316:10 amPMO - ORD
2 stops19h 09mITA Airways
Deal found 12/13$1,813
This KAYAK deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/235:50 pmORD - PMO
2 stops37h 05mSWISS
Fri 1/96:10 amPMO - ORD
2 stops17h 10mSWISS
Deal found 12/15$1,816

Find flight deals from Indiana to Sicily

Keep the following information in mind while searching for Indiana to Sicily flight deals. Data was last updated December 15, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$500
(FlightHub)

One-way from

$286
(Kiwi.com)
Provider with most accurate pricing for Indianapolis-Catania Fontanarossa flight deals.
Search Deals
Provider most trusted by Cheapflights users for Indianapolis-Catania Fontanarossa flights.
Search Deals
From Indiana to Sicily
Search Deals
One-way flight from Indiana to Sicily
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Indiana to Sicily that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 15, 2025.
Use the filters below to find and compare flights from Indiana to Sicily that are best for you.

Fly from

Indiana

Fly to

Sicily

Route

Depart

Return

Price

IndianapolisCatania

IND - CTA

INDCTA

Indianapolis

Tue 2/17

2:00 pm-11:35 am

2 stops15h 35m

Catania Fontanarossa

Tue 3/10

3:25 pm-6:50 pm

2 stops32h 25m

$500

IndianapolisPalermo

IND - PMO

INDPMO

Indianapolis

Mon 2/9

3:52 pm-11:40 am

2 stops37h 48m

Palermo Punta Raisi

Tue 2/17

7:10 pm-6:57 pm

2 stops29h 47m

$500

ChicagoPalermo

ORD - PMO

ORDPMO

Chicago O'Hare Intl

Sat 3/7

8:20 pm-8:30 am

1 stop29h 10m

Palermo Punta Raisi

Sun 3/15

6:45 pm-7:25 pm

1 stop30h 40m

$525

ChicagoCatania

ORD - CTA

ORDCTA

Chicago O'Hare Intl

Wed 3/18

12:50 pm-6:25 pm

1 stop23h 35m

Catania Fontanarossa

Thu 3/26

7:25 pm-7:25 pm

1 stop30h 00m

$540

ChicagoCatania

ORD - CTA

ORDCTA

Chicago O'Hare Intl

Wed 3/18

9:20 pm-6:25 pm

1 stop15h 05m

Catania Fontanarossa

Wed 3/25

9:35 am-7:25 pm

1 stop15h 50m

$540

ChicagoCatania

ORD - CTA

ORDCTA

Chicago O'Hare Intl

Wed 3/18

12:50 pm-6:25 pm

1 stop23h 35m

Catania Fontanarossa

Mon 4/6

9:30 am-9:40 am

1 stop31h 10m

$568

ChicagoCatania

ORD - CTA

ORDCTA

Chicago O'Hare Intl

Tue 1/27

11:50 am-8:35 am

1 stop13h 45m

Catania Fontanarossa

Tue 2/3

7:25 pm-6:25 pm

1 stop30h 00m

$569

ChicagoPalermo

ORD - PMO

ORDPMO

Chicago O'Hare Intl

Fri 4/3

7:50 pm-6:20 pm

1 stop15h 30m

Palermo Punta Raisi

Sun 4/12

12:15 pm-9:40 am

2 stops28h 25m

$573

ChicagoCatania

ORD - CTA

ORDCTA

Chicago O'Hare Intl

Wed 3/25

12:50 pm-6:25 pm

1 stop23h 35m

Catania Fontanarossa

Wed 4/8

9:30 am-9:40 am

1 stop31h 10m

$577

ChicagoPalermo

ORD - PMO

ORDPMO

Chicago O'Hare Intl

Sat 3/7

11:50 am-1:10 pm

2 stops18h 20m

Palermo Punta Raisi

Sun 3/15

6:45 pm-11:05 am

1 stop22h 20m

$587

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/14

Showing 1-10 of 41 results
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Best time to book a flight from Indiana to Sicily

Have a flexible travel schedule? Discover the best time to fly to Sicily from Indiana with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Indiana to Sicily

What is the cheapest time of day to fly from IN to SI?

Find hourly flight availability from Indiana to Sicily. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 15, 2025.

It’s typically best to fly out from Indiana to Sicily in the evening. Doing so could potentially save you 25% on the flight price compared to flying in the morning, which is usually more expensive.

Reviews of airlines servicing Sicily

Get insights into the airlines that provide service to Sicily. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Sicily. Reviews last updated December 15, 2025.
See what other customers who have flown with Lufthansa from Indiana to Sicily have to say. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Lufthansa
6.8
Okay
7,628 reviews

Food

6.3

Overall

6.8

Comfort

6.8

Crew

7.6

Boarding

7.0

Entertainment

6.4

Reviews

1 / 20
8.0
Excellent

Anonymous,Dec 2024

SFO - FRA

Convenient flight to my destination. Good entertainment options on board. I was seated close to some people who had noisy children which made sleeping a bit challenging.
Lufthansa
6.8
Okay
7,628 reviews
Lufthansa
6.8
Okay
7,628 reviews

Food

6.3

Overall

6.8

Comfort

6.8

Crew

7.6

Boarding

7.0

Entertainment

6.4

Reviews

1 / 20
8.0
Excellent

Anonymous,Dec 2024

SFO - FRA

Convenient flight to my destination. Good entertainment options on board. I was seated close to some people who had noisy children which made sleeping a bit challenging.

Related info for your journey

Find useful and relevant information for your journey from Indiana to Sicily. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Indiana to Sicily?

    For as low as $500, Lufthansa can have you in Sicily from Indiana in 15h 35m. Airlines will cover a distance of 5139 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • Can I find deals for flights from Indiana to Sicily that include hotel bookings?

    Yes. In addition to deals on Indiana to Sicily flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Indiana to Sicily?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Indiana to Sicily.

  • Can I find deals for business class flights from Indiana to Sicily?

    Yes. Cheapflights offers flight deals from Indiana to Sicily by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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Alternative routes for Indiana to Sicily

See prices for flight routes from nearby airports that may be better suited for you.
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Top airline flying from Indiana to Sicily

Discover the top airline that operate flights from Indiana to Sicily. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 15, 2025.
AirlineCheapestAverageFlexibilityOn-time
LufthansaCheapest$671Average$1,206FlexibilityNo cancel feeOn-time76%

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