Sicily

$339+ Cheap flights from Indiana to Sicily

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/20. Fares are subject to change and may not be available on all flights or dates of travel.
IND — CTA
Nov 19 — Nov 261
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Cheap flight deals from Indiana to Sicily

Keep the following information in mind while searching for Indiana to Sicily flight deals. Data was last updated October 20, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$502
(Mytrip)

One-way from

$339
(Kiwi.com)
Provider with most accurate pricing for Indianapolis-Catania Fontanarossa flight deals.
Provider most trusted by Cheapflights users for Indianapolis-Catania Fontanarossa flights.
From Indiana to Sicily
One-way flight from Indiana to Sicily

Find flight deals from Indiana to Sicily

Cheapest flights from Indiana to Sicily
Explore the most affordable flight options available from Indiana to Sicily. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 20, 2025.

This Mytrip deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/276:30 pmORD - PMO
2 stops20h 30mMultiple Airlines
Sat 12/611:50 pmPMO - ORD
2 stops24h 30mMultiple Airlines
Deal found 10/19$502
This Billigflug deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Billigflug is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/299:50 pmORD - PMO
1 stop12h 35mLufthansa
Fri 12/1212:10 pmPMO - ORD
1 stop13h 15mLufthansa
Deal found 10/19$514
This KAYAK deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/296:50 pmORD - PMO
1 stop12h 05mSWISS
Sun 2/12:45 pmPMO - ORD
1 stop32h 35mSWISS
Deal found 10/19$515
This Mytrip deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/46:30 pmORD - CTA
2 stops21h 50mMultiple Airlines
Thu 12/115:50 amCTA - ORD
2 stops18h 30mMultiple Airlines
Deal found 10/20$516
This Mytrip deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/48:15 pmORD - PMO
2 stops32h 10mMultiple Airlines
Thu 12/1112:15 pmPMO - ORD
1 stop14h 50mMultiple Airlines
Deal found 10/19$527
This KAYAK deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/299:50 pmORD - PMO
1 stop12h 35mLufthansa
Fri 2/612:10 pmPMO - ORD
1 stop13h 15mLufthansa
Deal found 10/19$532
This Delta deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/2811:20 amORD - CTA
2 stops41h 35mDelta
Sun 12/1412:45 pmCTA - ORD
1 stop32h 35mDelta
Deal found 10/19$535
This Bravofly deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Bravofly is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/411:50 amORD - CTA
1 stop23h 35mTurkish Airlines
Thu 12/117:25 pmCTA - ORD
1 stop21h 40mTurkish Airlines
Deal found 10/20$538
This KAYAK deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/264:20 pmORD - PMO
1 stop11h 45mLufthansa
Sat 2/712:10 pmPMO - ORD
1 stop13h 15mLufthansa
Deal found 10/19$545
This FlightHub deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/198:00 amORD - PMO
2 stops20h 05mMultiple Airlines
Sun 1/186:25 pmPMO - ORD
1 stop31h 00mMultiple Airlines
Deal found 10/19$551
This FlightHub deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/2610:00 amORD - PMO
2 stops18h 05mMultiple Airlines
Thu 2/52:45 pmPMO - ORD
1 stop32h 35mMultiple Airlines
Deal found 10/19$552
This Booking.com deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/279:50 pmORD - PMO
1 stop30h 30mLufthansa
Sat 12/612:10 pmPMO - ORD
1 stop13h 15mLufthansa
Deal found 10/19$553

Cheapflights Fare Finder

 
Customize your flight search to find flights from Indiana to Sicily that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 20, 2025.
Use the filters below to find and compare flights from Indiana to Sicily that are best for you.

Fly from

Indiana

Fly to

Sicily

Route

Depart

Return

Price

ChicagoCatania

ORD - CTA

ORDCTA

Chicago O'Hare Intl

Tue 3/24

12:50 pm-8:35 am

1 stop13h 45m

Catania Fontanarossa

Sun 3/29

7:20 pm-9:40 am

1 stop21h 20m

$516

ChicagoCatania

ORD - CTA

ORDCTA

Chicago O'Hare Intl

Fri 11/28

11:20 am-11:55 am

2 stops41h 35m

Catania Fontanarossa

Sun 12/14

12:45 pm-2:20 pm

1 stop32h 35m

$535

ChicagoCatania

ORD - CTA

ORDCTA

Chicago O'Hare Intl

Fri 11/28

4:25 pm-3:25 pm

1 stop16h 00m

Catania Fontanarossa

Sun 12/14

12:45 pm-2:20 pm

1 stop32h 35m

$535

ChicagoCatania

ORD - CTA

ORDCTA

Chicago O'Hare Intl

Thu 12/4

11:50 am-6:25 pm

1 stop23h 35m

Catania Fontanarossa

Thu 12/11

7:25 pm-10:05 am

1 stop21h 40m

$538

ChicagoPalermo

ORD - PMO

ORDPMO

Chicago O'Hare Intl

Wed 11/19

4:20 pm-11:05 am

1 stop11h 45m

Palermo Punta Raisi

Sun 1/18

6:25 pm-6:25 pm

1 stop31h 00m

$545

ChicagoCatania

MDW - CTA

MDWCTA

Chicago Midway

Thu 12/4

1:14 pm-1:20 pm

2 stops17h 06m

Catania Fontanarossa

Thu 12/11

10:15 am-11:47 pm

2 stops20h 32m

$555

ChicagoPalermo

ORD - PMO

ORDPMO

Chicago O'Hare Intl

Wed 11/5

8:20 pm-8:30 am

1 stop29h 10m

Palermo Punta Raisi

Wed 11/12

6:45 pm-6:25 pm

1 stop30h 40m

$556

ChicagoPalermo

MDW - PMO

MDWPMO

Chicago Midway

Sat 11/29

1:15 pm-1:40 pm

2 stops17h 25m

Palermo Punta Raisi

Fri 12/12

10:00 am-11:49 pm

2 stops20h 49m

$556

ChicagoCatania

ORD - CTA

ORDCTA

Chicago O'Hare Intl

Thu 12/4

10:45 am-6:30 pm

2 stops24h 45m

Catania Fontanarossa

Thu 12/11

8:50 pm-2:20 pm

1 stop24h 30m

$564

IndianapolisCatania

IND - CTA

INDCTA

Indianapolis

Mon 11/17

5:44 pm-11:35 am

2 stops35h 51m

Catania Fontanarossa

Mon 11/24

12:15 pm-5:49 pm

2 stops35h 34m

$566

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/20

Showing 1-10 of 44 results
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Best time to book a flight from Indiana to Sicily

Have a flexible travel schedule? Discover the best time to fly to Sicily from Indiana with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Indiana to Sicily

What is the cheapest time of day to fly from IN to SI?

Find hourly flight availability from Indiana to Sicily. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 20, 2025.

It’s typically best to fly out from Indiana to Sicily in the evening. Doing so could potentially save you 25% on the flight price compared to flying in the morning, which is usually more expensive.

Reviews of airlines servicing Sicily

Get insights into the airlines that provide service to Sicily. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Sicily. Reviews last updated October 20, 2025.
See what other customers who have flown with Lufthansa from Indiana to Sicily have to say. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.

Comfort

6.8

Food

6.3

Crew

7.6

Entertainment

6.4

Boarding

7.0

Overall

6.8

Reviews

1 / 20
8.0
Excellent

Anonymous,Dec 2024

SFO - FRA

Convenient flight to my destination. Good entertainment options on board. I was seated close to some people who had noisy children which made sleeping a bit challenging.

Comfort

6.8

Food

6.3

Crew

7.6

Entertainment

6.4

Boarding

7.0

Overall

6.8

Reviews

1 / 20
8.0
Excellent

Anonymous,Dec 2024

SFO - FRA

Convenient flight to my destination. Good entertainment options on board. I was seated close to some people who had noisy children which made sleeping a bit challenging.

Related info for your journey

Find useful and relevant information for your journey from Indiana to Sicily. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • How long is the flight from Indiana to Sicily?

    For as low as $516, Turkish Airlines can have you in Sicily from Indiana in 13h 45m. Airlines will cover a distance of 5114 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines to fly from Indiana to Sicily one-way?

    For one-way options, check prices for ITA Airways. According to our data, you can fly for as low as $419. Users have also found prices from $467 and $494 on Turkish Airlines and SWISS, respectively.

  • Can I find deals for flights from Indiana to Sicily that include hotel bookings?

    Yes. In addition to deals on Indiana to Sicily flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Indiana to Sicily?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Indiana to Sicily.

  • Can I find deals for business class flights from Indiana to Sicily?

    Yes. Cheapflights offers flight deals from Indiana to Sicily by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Indiana to Sicily

See prices for flight routes from nearby airports that may be better suited for you.

Top airline flying from Indiana to Sicily

Discover the top airline that operate flights from Indiana to Sicily. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 20, 2025.
AirlineCheapestAverageFlexibilityOn-time
LufthansaCheapest$810Average$1,315FlexibilityNo cancel feeOn-time76%

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