$390+ Cheap flights from Des Moines (DSM) to Sedona, AZ
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/21. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — PHX
Oct 7 — Oct 141
Round-trip
1 adult, Economy
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Find cheap flights from Des Moines to Sedona with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Des Moines to Sedona
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Best
Last-minute
One-way
Cheapest flights from Des Moines to SedonaExplore the most affordable flight options available from Des Moines to Sedona. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 7, 2026.
Explore the most affordable flight options available from Des Moines to Sedona. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 7, 2026.
This American Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/176:14 am -
1 stop7h 51m
Wed 10/287:15 am -
1 stop5h 56m
Deal found 9/5![American Airlines logo]()
$524
This American Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/185:06 am -
1 stop8h 10m
Tue 10/2712:45 pm -
1 stop8h 22m
Deal found 9/5![American Airlines logo]()
$554
This American Airlines deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/35:05 am -
1 stop6h 40m
Sun 12/611:16 am -
1 stop5h 11m
Deal found 9/2![American Airlines logo]()
$584
This American Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/305:06 am -
1 stop6h 58m
Sun 11/87:37 am -
1 stop5h 04m
Deal found 9/5![American Airlines logo]()
$619
This American Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/302:17 pm -
1 stop7h 50m
Sun 10/410:40 am -
1 stop4h 28m
Deal found 9/3![American Airlines logo]()
$624
This American Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates ” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/185:06 am -
1 stop6h 58m
Wed 10/286:15 am -
2 stops9h 53m
Deal found 9/5![American Airlines logo]()
$625
This American Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/116:41 am -
1 stop7h 12m
Mon 9/215:14 pm -
1 stop4h 45m
Deal found 9/3![American Airlines logo]()
$654
This American Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/232:30 pm -
1 stop6h 49m
Tue 12/298:50 pm -
1 stop15h 55m
Deal found 9/5![American Airlines logo]()
$700
Best flights from Des Moines to SedonaDiscover carefully curated flight deals from Des Moines to Sedona that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 7, 2026.
Discover carefully curated flight deals from Des Moines to Sedona that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 7, 2026.
This American Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/36:02 pm -
1 stop6h 42m
Sun 12/67:37 am -
1 stop5h 04m
Deal found 9/3![American Airlines logo]()
$584
This American Airlines deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/125:00 am -
1 stop8h 10m
Mon 11/1612:41 pm -
1 stop6h 37m
Deal found 9/2![American Airlines logo]()
$584
This American Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/302:17 pm -
1 stop7h 50m
Sun 10/410:40 am -
1 stop4h 28m
Deal found 9/7![American Airlines logo]()
$624
This American Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/302:30 pm -
1 stop5h 14m
Sat 11/712:41 pm -
2 stops9h 49m
Deal found 9/5![American Airlines logo]()
$625
This American Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/305:06 am -
1 stop6h 58m
Sat 11/1412:41 pm -
2 stops9h 45m
Deal found 9/5![American Airlines logo]()
$625
This American Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/225:06 am -
1 stop6h 58m
Tue 10/2710:34 am -
2 stops11h 40m
Deal found 9/7![American Airlines logo]()
$625
Last-minute flights from Des Moines to SedonaDiscover last-minute flight deals from Des Moines to Sedona. Data last updated September 7, 2026 and is based on user searches.
Discover last-minute flight deals from Des Moines to Sedona. Data last updated September 7, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/116:41 am -
1 stop7h 12m
Mon 9/215:14 pm -
1 stop4h 45m
Deal found 9/3![American Airlines logo]()
$654
This American Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/302:17 pm -
1 stop7h 50m
Sun 10/410:40 am -
1 stop4h 28m
Deal found 9/3![American Airlines logo]()
$624
This American Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/176:14 am -
1 stop7h 51m
Wed 10/287:15 am -
1 stop5h 56m
Deal found 9/5![American Airlines logo]()
$524
This American Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/185:06 am -
1 stop8h 10m
Tue 10/2712:45 pm -
1 stop8h 22m
Deal found 9/5![American Airlines logo]()
$554
This American Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/186:14 am -
1 stop7h 51m
Mon 10/2612:45 pm -
1 stop8h 22m
Deal found 9/5![American Airlines logo]()
$584
This American Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/185:06 am -
1 stop6h 58m
Wed 10/286:15 am -
2 stops9h 53m
Deal found 9/5![American Airlines logo]()
$625
This American Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/236:14 am -
1 stop7h 51m
Sun 11/112:41 pm -
2 stops9h 24m
Deal found 9/5![American Airlines logo]()
$702
This American Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/299:26 am -
2 stops10h 18m
Sat 11/147:37 am -
2 stops9h 09m
Deal found 9/5![American Airlines logo]()
$722
This American Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/305:06 am -
1 stop6h 58m
Sun 11/87:37 am -
1 stop5h 04m
Deal found 9/5![American Airlines logo]()
$619
One-way flights from Des Moines to SedonaSearch for one-way flight options from Des Moines to Sedona. Find affordable one-way fares based on user searches. Data last updated September 7, 2026.
Search for one-way flight options from Des Moines to Sedona. Find affordable one-way fares based on user searches. Data last updated September 7, 2026.
This American Airlines deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/215:06 am -
1 stop6h 58m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/6![American Airlines logo]()
$390
This American Airlines deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/226:29 pm -
1 stop4h 54m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/6![American Airlines logo]()
$410
This American Airlines deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/209:48 am -
2 stops12h 51m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/6![American Airlines logo]()
$437
This American Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/2510:35 am -
2 stops11h 32m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/3![American Airlines logo]()
$493
Find flight deals from Des Moines to Sedona
Keep the following information in mind while searching for Des Moines to Sedona flight deals. Data was last updated September 7, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $524 (American Airlines) |
One-way from | $390 (American Airlines) |
Cheapflights Fare Finder
Customize your flight search to find flights from Des Moines to Sedona that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 7, 2026.
Use the filters below to find and compare flights from Des Moines to Sedona that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Des MoinesFlagstaff
DSM Des Moines - FLG Flagstaff Pulliam
DSMFLG
Des Moines
Sat 9/26
5:30 am-10:07 am
1 stop6h 37m
Flagstaff Pulliam
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$390
Des MoinesFlagstaff
DSM Des Moines - FLG Flagstaff Pulliam
DSMFLG
Des Moines
Wed 10/21
5:06 am-11:16 am
1 stop8h 10m
Flagstaff Pulliam
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$390
Des MoinesFlagstaff
DSM Des Moines - FLG Flagstaff Pulliam
DSMFLG
Des Moines
Tue 10/20
5:06 am-10:04 am
1 stop6h 58m
Flagstaff Pulliam
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$390
Quickest round-trip
Des MoinesFlagstaff
DSM Des Moines - FLG Flagstaff Pulliam
DSMFLG
Des Moines
Thu 10/22
6:29 pm-9:23 pm
1 stop4h 54m
Flagstaff Pulliam
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$410
Des MoinesFlagstaff
DSM Des Moines - FLG Flagstaff Pulliam
DSMFLG
Des Moines
Thu 12/3
6:02 pm-11:44 pm
1 stop6h 42m
Flagstaff Pulliam
Sun 12/6
7:37 am-1:41 pm
1 stop5h 04m
$584
Des MoinesFlagstaff
DSM Des Moines - FLG Flagstaff Pulliam
DSMFLG
Des Moines
Thu 11/12
5:00 am-12:10 pm
1 stop8h 10m
Flagstaff Pulliam
Mon 11/16
12:41 pm-8:18 pm
1 stop6h 37m
$584
Des MoinesFlagstaff
DSM Des Moines - FLG Flagstaff Pulliam
DSMFLG
Des Moines
Wed 9/30
2:17 pm-8:07 pm
1 stop7h 50m
Flagstaff Pulliam
Sun 10/4
10:40 am-5:08 pm
1 stop4h 28m
$624
Des MoinesFlagstaff
DSM Des Moines - FLG Flagstaff Pulliam
DSMFLG
Des Moines
Fri 10/30
2:30 pm-5:44 pm
1 stop5h 14m
Flagstaff Pulliam
Sat 11/7
12:41 pm-11:30 pm
2 stops9h 49m
$625
Des MoinesFlagstaff
DSM Des Moines - FLG Flagstaff Pulliam
DSMFLG
Des Moines
Fri 10/30
5:06 am-10:04 am
1 stop6h 58m
Flagstaff Pulliam
Sat 11/14
12:41 pm-11:26 pm
2 stops9h 45m
$625
Des MoinesFlagstaff
DSM Des Moines - FLG Flagstaff Pulliam
DSMFLG
Des Moines
Thu 10/22
5:06 am-10:04 am
1 stop6h 58m
Flagstaff Pulliam
Tue 10/27
10:34 am-12:14 am
2 stops11h 40m
$625
Sorted by cheapest first
Best time to book a flight from Des Moines to Sedona
Have a flexible travel schedule? Discover the best time to fly to Sedona from Des Moines with our price prediction graph.
DSM-FLG
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Des Moines to Sedona
DSM-SE9
DSM-FLG
What is the cheapest time of day to fly from DSM to SE9?
Find hourly flight availability from Des Moines to Sedona. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 7, 2026.
A simple way to save on the total cost of your ticket is to fly from Des Moines to Sedona in the afternoon. If you’re flexible enough to do this you can expect to save up to 51% on your trip compared to booking a flight in the evening.
Related info for your journey
Find useful and relevant information for your journey from Des Moines to Sedona. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
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Alternative routes for Des Moines to Sedona
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Sedona by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Des Moines to Sedona by cabin class
Find flights from Des Moines to Sedona, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Des Moines and Sedona flights
Browse other Des Moines and Sedona flight options. Last updated on September 7, 2026.
Other flights from Des Moines
Browse through other flights departing from Des Moines. Flights are based on user searches made on Cheapflights and were last updated on September 7, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Des Moines to Sedona flights
Consider these flights traveling from Des Moines to Sedona.
Top 7 airlines flying from Des Moines to Sedona
Discover the top 7 airlines that operate flights from Des Moines to Sedona. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 7, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$152 | Average$340 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$161 | Average$303 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$164 | Average$292 | FlexibilityNo cancel fee | On-time88% | |
| Cheapest$187 | Average$362 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$207 | Average$374 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$212 | Average$393 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$219 | Average$328 | FlexibilityNo cancel fee | On-time62% |