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Sao Paulo

$1,491+ Cheap flights from Knoxville (TYS) to Sao Paulo, Brazil (SAO)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/12. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — SAO
Aug 5 — Aug 121
Tue 8/5
Tue 8/12
1 adult, Economy
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Find flight deals from Knoxville to Sao Paulo

Cheapest flights from Knoxville to Sao Paulo
Explore the most affordable flight options available from Knoxville to Sao Paulo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 31, 2025.

This FlightHub deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/127:15 pmTYS - GRU
2 stops31h 45mLATAM Airlines
Fri 1/29:35 amGRU - TYS
2 stops27h 19mLATAM Airlines
Deal found 7/30$1,491
This American Airlines deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/124:03 pmTYS - GRU
2 stops14h 02mAmerican Airlines
Thu 1/112:15 amGRU - TYS
1 stop19h 48mAmerican Airlines
Deal found 7/30$1,798
This Avianca deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/129:40 amTYS - GRU
2 stops27h 45mMultiple Airlines
Thu 1/11:50 amGRU - TYS
2 stops16h 58mMultiple Airlines
Deal found 7/30$1,851

Cheapflights Fare Finder

 
Customize your flight search to find flights from Knoxville to Sao Paulo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 31, 2025.
Use the filters below to find and compare flights from Knoxville to Sao Paulo that are best for you.

Fly from

Knoxville

Fly to

Sao Paulo

Route

Depart

Return

Price

KnoxvilleSao Paulo

TYS - GRU

TYSGRU

Knoxville McGhee Tyson

Fri 12/12

7:15 pm-5:00 am

2 stops31h 45m

Sao Paulo Guarulhos Intl

Fri 1/2

9:35 am-10:54 am

2 stops27h 19m

$1,491

KnoxvilleSao Paulo

TYS - GRU

TYSGRU

Knoxville McGhee Tyson

Fri 12/12

7:01 am-8:05 am

1 stop23h 04m

Sao Paulo Guarulhos Intl

Thu 1/1

12:15 am-6:03 pm

1 stop19h 48m

$1,806

KnoxvilleSao Paulo

TYS - GRU

TYSGRU

Knoxville McGhee Tyson

Fri 12/12

9:40 am-3:25 pm

2 stops27h 45m

Sao Paulo Guarulhos Intl

Thu 1/1

1:50 am-4:48 pm

2 stops16h 58m

$1,851

KnoxvilleSao Paulo

TYS - GRU

TYSGRU

Knoxville McGhee Tyson

Thu 1/15

10:16 am-10:35 am

2 stops22h 19m

$2,145

KnoxvilleSao Paulo

TYS - GRU

TYSGRU

Knoxville McGhee Tyson

Thu 1/15

4:00 pm-5:40 am

1 stop11h 40m

$2,192

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/30

Best time to book a flight from Knoxville to Sao Paulo

Have a flexible travel schedule? Discover the best time to fly to Sao Paulo from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to Sao Paulo

What is the cheapest time of day to fly from TYS to SAO?

Find hourly flight availability from Knoxville to Sao Paulo. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated July 31, 2025.

When flying from Knoxville to Sao Paulo, the time of day you fly usually plays a role in the price. Save by searching for a flight in the morning, which can drop the price by up to 27% versus a flight at noon.

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Sao Paulo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Knoxville to Sao Paulo?

    Knoxville McGhee Tyson (TYS) is the airport you will fly out of if you book a flight from Knoxville to Sao Paulo. You should not have trouble finding flights to Sao Paulo from McGhee Tyson; the airport handles an average of 0 outbound flights to Sao Paulo per day. You should also have plenty of airline options to choose from since 0 airlines have flights from the Knoxville airport to Sao Paulo. It is only a 11.3 mi journey to McGhee Tyson (TYS) from Knoxville’s city center.

  • Can I find deals for flights from Knoxville to Sao Paulo that include hotel bookings?

    Yes. In addition to deals on Knoxville to Sao Paulo flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Sao Paulo?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Sao Paulo.

  • Can I find deals for business class flights from Knoxville to Sao Paulo?

    Yes. Cheapflights offers flight deals from Knoxville to Sao Paulo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Knoxville to Sao Paulo?

    Currently, September is the cheapest month in which you can book a flight from Knoxville to Sao Paulo (average of $678). Flying from Knoxville to Sao Paulo in December is currently the most expensive (average of $1,209). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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