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Sao Paulo

$376+ Cheap flights from Knoxville (TYS) to Sao Paulo, Brazil (SAO)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/2. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — SAO
Jan 28 — Feb 41
Wed 1/28
Wed 2/4
1 adult, Economy
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Cheap flight deals from Knoxville to Sao Paulo

Cheapest flights from Knoxville to Sao Paulo
Explore the most affordable flight options available from Knoxville to Sao Paulo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 29, 2025.

This United Airlines deal was found by Cheapflights users on 12/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/286:45 amTYS - GRU
1 stop22h 30mUnited Airlines
Sat 1/310:15 pmGRU - TYS
1 stop14h 56mUnited Airlines
Deal found 12/27$7,275
This business-class.com deal was found by Cheapflights users on 12/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure business-class.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/284:31 pmTYS - GRU
3 stops19h 39mLATAM Airlines
Sat 1/35:45 pmGRU - TYS
2 stops17h 32mLATAM Airlines
Deal found 12/27$7,546

Find flight deals from Knoxville to Sao Paulo

Discover tips and strategies to find the most affordable flight options for your journey from Knoxville (TYS) to Sao Paulo (SAO). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated December 29, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$1,028
(KAYAK)

One-way from

$376
(Kiwi.com)
Provider with most accurate pricing for Knoxville McGhee Tyson-Sao Paulo (SAO) flight deals.
Search Deals
Provider most trusted by Cheapflights users for Knoxville McGhee Tyson-Sao Paulo (SAO) flights.
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From Knoxville McGhee Tyson to Sao Paulo (SAO)
Search Deals
One-way flight from Knoxville McGhee Tyson to Sao Paulo (SAO)
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Knoxville to Sao Paulo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 29, 2025.
Use the filters below to find and compare flights from Knoxville to Sao Paulo that are best for you.

Fly from

Knoxville

Fly to

Sao Paulo

Route

Depart

Return

Price

KnoxvilleSao Paulo

TYS - GRU

TYSGRU

Knoxville McGhee Tyson

Sun 3/1

6:41 pm-8:00 pm

2 stops23h 19m

Sao Paulo Guarulhos Intl

Wed 4/1

11:45 pm-9:16 am

2 stops34h 31m

$1,028

KnoxvilleSao Paulo

TYS - GRU

TYSGRU

Knoxville McGhee Tyson

Sun 3/1

5:27 pm-7:15 am

1 stop35h 48m

Sao Paulo Guarulhos Intl

Wed 4/1

10:20 pm-1:17 pm

1 stop15h 57m

$1,048

KnoxvilleSao Paulo

TYS - GRU

TYSGRU

Knoxville McGhee Tyson

Wed 4/1

3:13 pm-5:40 am

1 stop13h 27m

Sao Paulo Guarulhos Intl

Wed 4/8

7:30 am-11:51 pm

2 stops17h 21m

$3,600

KnoxvilleSao Paulo

TYS - GRU

TYSGRU

Knoxville McGhee Tyson

Wed 4/1

5:48 pm-9:45 am

1 stop14h 57m

Sao Paulo Guarulhos Intl

Wed 4/8

9:50 pm-7:56 pm

1 stop23h 06m

$3,600

KnoxvilleSao Paulo

TYS - GRU

TYSGRU

Knoxville McGhee Tyson

Mon 2/2

12:55 pm-3:50 am

2 stops36h 55m

$418

KnoxvilleSao Paulo

TYS - GRU

TYSGRU

Knoxville McGhee Tyson

Fri 3/27

10:55 am-7:15 am

1 stop19h 20m

$594

KnoxvilleSao Paulo

TYS - GRU

TYSGRU

Knoxville McGhee Tyson

Fri 3/27

10:04 am-5:20 am

2 stops18h 16m

$598

KnoxvilleSao Paulo

TYS - GRU

TYSGRU

Knoxville McGhee Tyson

Mon 2/2

2:37 pm-5:40 am

1 stop13h 03m

$656

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/28

Compare providers for flights from Knoxville to Sao Paulo

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Knoxville to Sao Paulo in December.
ProviderPrice AccuracyTrust Score*
eDreamsPrice Accuracy3 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Knoxville-Sao Paulo flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Knoxville-Sao Paulo flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Knoxville-Sao Paulo flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Knoxville-Sao Paulo flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Knoxville-Sao Paulo flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Knoxville to Sao Paulo

Have a flexible travel schedule? Discover the best time to fly to Sao Paulo from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to Sao Paulo
No data available for this route at this time. Please check back soon.

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Sao Paulo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Knoxville to Sao Paulo?

    Knoxville McGhee Tyson (TYS) is the airport you will fly out of if you book a flight from Knoxville to Sao Paulo. You should not have trouble finding flights to Sao Paulo from McGhee Tyson; the airport handles an average of 0 outbound flights to Sao Paulo per day. You should also have plenty of airline options to choose from since 0 airlines have flights from the Knoxville airport to Sao Paulo. It is only a 11.3 mi journey to McGhee Tyson (TYS) from Knoxville’s city center.

  • How long is the flight from Knoxville to Sao Paulo?

    For as low as $1,028, LATAM Airlines can have you in Sao Paulo from Knoxville in 23h 19m. There are 4768 mi between Knoxville and Sao Paulo.

  • Can I find deals for flights from Knoxville to Sao Paulo that include hotel bookings?

    Yes. In addition to deals on Knoxville to Sao Paulo flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Sao Paulo?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Sao Paulo.

  • Can I find deals for business class flights from Knoxville to Sao Paulo?

    Yes. Cheapflights offers flight deals from Knoxville to Sao Paulo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

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