$375+ Cheap flights from Knoxville (TYS) to San Pedro Sula (SAP)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/2. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — SAP
Nov 18 — Nov 251
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from Knoxville to San Pedro Sula with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Knoxville to San Pedro Sula
Cheapest
Best
Last-minute
One-way
Cheapest flights from Knoxville to San Pedro SulaExplore the most affordable flight options available from Knoxville to San Pedro Sula. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 19, 2026.
Explore the most affordable flight options available from Knoxville to San Pedro Sula. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 19, 2026.
This American Airlines deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/163:55 pm -
2 stops21h 19m
Mon 11/233:26 pm -
1 stop8h 26m
Deal found 10/18![American Airlines logo]()
$797
This United Airlines deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/266:00 am -
2 stops17h 57m
Wed 1/201:41 pm -
1 stop7h 18m
Deal found 10/18![United Airlines logo]()
$935
This American Airlines deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/147:16 pm -
1 stop20h 24m
Sat 11/211:36 pm -
2 stops20h 00m
Deal found 10/15![American Airlines logo]()
$943
This American Airlines deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/305:15 am -
1 stop16h 14m
Thu 1/144:06 pm -
2 stops18h 20m
Deal found 10/15![American Airlines logo]()
$944
This United Airlines deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/216:55 am -
1 stop17h 02m
Mon 1/111:41 pm -
1 stop7h 18m
Deal found 10/14![United Airlines logo]()
$1,033
This United Airlines deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/307:35 pm -
2 stops28h 10m
Thu 1/141:41 pm -
3 stops53h 10m
Deal found 10/15![United Airlines logo]()
$1,095
This American Airlines deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/265:15 am -
1 stop7h 33m
Wed 1/2012:41 pm -
1 stop10h 18m
Deal found 10/18![American Airlines logo]()
$1,124
Best flights from Knoxville to San Pedro SulaDiscover carefully curated flight deals from Knoxville to San Pedro Sula that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 19, 2026.
Discover carefully curated flight deals from Knoxville to San Pedro Sula that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 19, 2026.
This American Airlines deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/215:15 pm -
2 stops19h 26m
Sun 1/314:06 pm -
1 stop6h 53m
Deal found 10/15![American Airlines logo]()
$723
This United Airlines deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/266:00 am -
2 stops17h 57m
Wed 1/201:41 pm -
1 stop7h 18m
Deal found 10/18![United Airlines logo]()
$935
This Ovago deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ovago is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/307:35 pm -
2 stops28h 10m
Thu 1/141:41 pm -
2 stops19h 29m
Deal found 10/15![Multiple Airlines logo]()
$935
This American Airlines deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/163:55 pm -
2 stops21h 19m
Mon 11/233:26 pm -
1 stop8h 26m
Deal found 10/18![American Airlines logo]()
$797
This United Airlines deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/216:55 am -
1 stop17h 02m
Mon 1/111:41 pm -
1 stop7h 18m
Deal found 10/14![United Airlines logo]()
$1,033
This United Airlines deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/55:55 pm -
2 stops19h 40m
Sat 1/1612:15 am -
2 stops32h 55m
Deal found 10/15![United Airlines logo]()
$1,074
This United Airlines deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/307:35 pm -
2 stops28h 10m
Thu 1/141:41 pm -
3 stops53h 10m
Deal found 10/15![United Airlines logo]()
$1,095
Last-minute flights from Knoxville to San Pedro SulaDiscover last-minute flight deals from Knoxville to San Pedro Sula. Data last updated October 19, 2026 and is based on user searches.
Discover last-minute flight deals from Knoxville to San Pedro Sula. Data last updated October 19, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/147:16 pm -
1 stop20h 24m
Sat 11/211:36 pm -
2 stops20h 00m
Deal found 10/15![American Airlines logo]()
$943
This American Airlines deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/163:55 pm -
2 stops21h 19m
Mon 11/233:26 pm -
1 stop8h 26m
Deal found 10/18![American Airlines logo]()
$797
One-way flights from Knoxville to San Pedro SulaSearch for one-way flight options from Knoxville to San Pedro Sula. Find affordable one-way fares based on user searches. Data last updated October 19, 2026.
Search for one-way flight options from Knoxville to San Pedro Sula. Find affordable one-way fares based on user searches. Data last updated October 19, 2026.
This Kiwi.com deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/22:12 pm -
3 stops58h 20m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/16![Multiple Airlines logo]()
$375
This Kiwi.com deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/138:35 am -
3 stops53h 09m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/15![Multiple Airlines logo]()
$386
This United Airlines deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/107:00 am -
1 stop6h 35m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/15![United Airlines logo]()
$448
This United Airlines deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/147:00 am -
1 stop6h 35m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/15![United Airlines logo]()
$456
This American Airlines deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/23:55 pm -
2 stops21h 19m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/16![American Airlines logo]()
$482
This American Airlines deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/168:52 pm -
2 stops16h 22m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/15![American Airlines logo]()
$488
This Avianca deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/107:00 am -
2 stops17h 40m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/15![Multiple Airlines logo]()
$491
This Kiwi.com deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/229:26 am -
3 stops48h 44m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/19![Multiple Airlines logo]()
$493
This United Airlines deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/17:35 pm -
2 stops18h 00m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/16![United Airlines logo]()
$498
Find flight deals from Knoxville to San Pedro Sula
Discover tips and strategies to find the most affordable flight options for your journey from Knoxville (TYS) to San Pedro Sula (SAP). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 19, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $705 (Delta) |
One-way from | $375 (Kiwi.com) |
Cheapflights Fare Finder
Customize your flight search to find flights from Knoxville to San Pedro Sula that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 19, 2026.
Use the filters below to find and compare flights from Knoxville to San Pedro Sula that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
KnoxvilleSan Pedro Sula
TYS Knoxville McGhee Tyson - SAP San Pedro Sula Ramon Villeda
TYSSAP
Knoxville McGhee Tyson
Fri 11/13
8:35 am-12:44 pm
3 stops53h 09m
San Pedro Sula Ramon Villeda
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$386
Quickest round-trip
KnoxvilleSan Pedro Sula
TYS Knoxville McGhee Tyson - SAP San Pedro Sula Ramon Villeda
TYSSAP
Knoxville McGhee Tyson
Tue 11/10
7:00 am-12:35 pm
1 stop6h 35m
San Pedro Sula Ramon Villeda
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$448
KnoxvilleSan Pedro Sula
TYS Knoxville McGhee Tyson - SAP San Pedro Sula Ramon Villeda
TYSSAP
Knoxville McGhee Tyson
Sat 11/14
7:00 am-12:35 pm
1 stop6h 35m
San Pedro Sula Ramon Villeda
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$456
KnoxvilleSan Pedro Sula
TYS Knoxville McGhee Tyson - SAP San Pedro Sula Ramon Villeda
TYSSAP
Knoxville McGhee Tyson
Tue 12/22
9:26 am-9:10 am
3 stops48h 44m
San Pedro Sula Ramon Villeda
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$493
KnoxvilleSan Pedro Sula
TYS Knoxville McGhee Tyson - SAP San Pedro Sula Ramon Villeda
TYSSAP
Knoxville McGhee Tyson
Sun 11/1
7:35 pm-12:35 pm
2 stops18h 00m
San Pedro Sula Ramon Villeda
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$498
KnoxvilleSan Pedro Sula
TYS Knoxville McGhee Tyson - SAP San Pedro Sula Ramon Villeda
TYSSAP
Knoxville McGhee Tyson
Sun 11/1
6:00 am-2:40 pm
1 stop9h 40m
San Pedro Sula Ramon Villeda
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$531
KnoxvilleSan Pedro Sula
TYS Knoxville McGhee Tyson - SAP San Pedro Sula Ramon Villeda
TYSSAP
Knoxville McGhee Tyson
Mon 11/16
7:00 am-12:35 pm
1 stop6h 35m
San Pedro Sula Ramon Villeda
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$660
KnoxvilleSan Pedro Sula
TYS Knoxville McGhee Tyson - SAP San Pedro Sula Ramon Villeda
TYSSAP
Knoxville McGhee Tyson
Thu 1/21
5:15 pm-11:41 am
2 stops19h 26m
San Pedro Sula Ramon Villeda
Sun 1/31
4:06 pm-11:59 pm
1 stop6h 53m
$723
KnoxvilleSan Pedro Sula
TYS Knoxville McGhee Tyson - SAP San Pedro Sula Ramon Villeda
TYSSAP
Knoxville McGhee Tyson
Mon 11/16
3:55 pm-12:14 pm
2 stops21h 19m
San Pedro Sula Ramon Villeda
Mon 11/23
3:26 pm-12:52 am
1 stop8h 26m
$797
KnoxvilleSan Pedro Sula
TYS Knoxville McGhee Tyson - SAP San Pedro Sula Ramon Villeda
TYSSAP
Knoxville McGhee Tyson
Mon 11/2
7:00 am-12:35 pm
1 stop6h 35m
San Pedro Sula Ramon Villeda
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$813
Showing 1-10 of 15 resultsSorted by cheapest first
Compare providers for flights from Knoxville to San Pedro Sula
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Knoxville to San Pedro Sula in October.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Knoxville-San Pedro Sula flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Knoxville-San Pedro Sula flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Knoxville-San Pedro Sula flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Knoxville-San Pedro Sula flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Knoxville-San Pedro Sula flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Knoxville to San Pedro Sula
Have a flexible travel schedule? Discover the best time to fly to San Pedro Sula from Knoxville with our price prediction graph.
TYS-SAP
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Reviews of airlines servicing San Pedro Sula
Get insights into the airlines that provide service to San Pedro Sula. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Pedro Sula. Reviews last updated October 19, 2026.
Read through reviews of airlines operating flights from Knoxville to San Pedro Sula, such as American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Overall
7.0
Food
6.4
Boarding
7.4
Entertainment
6.8
Comfort
7.1
Crew
7.9
Reviews
1 / 20
10.0
ExcellentLinda,Jul 2026
ROA - CLT
Overall
7.0
Food
6.4
Boarding
7.4
Entertainment
6.8
Comfort
7.1
Crew
7.9
Reviews
1 / 20
10.0
ExcellentLinda,Jul 2026
ROA - CLT
Related info for your journey
Find useful and relevant information for your journey from Knoxville to San Pedro Sula. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
Other flight options
Other flights from Knoxville
Popular flights
San Pedro Sula flight routes
Alternative routes for Knoxville to San Pedro Sula
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to San Pedro Sula by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Knoxville to San Pedro Sula by cabin class
Find flights from Knoxville to San Pedro Sula, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Knoxville and San Pedro Sula flights
Browse other Knoxville and San Pedro Sula flight options. Last updated on October 19, 2026.
Other flights from Knoxville
Browse through other flights departing from Knoxville. Flights are based on user searches made on Cheapflights and were last updated on October 19, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Other flights to San Pedro Sula
Explore flights to San Pedro Sula departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on October 19, 2026.
Top airline flying from Knoxville to San Pedro Sula
Discover the top airline that operate flights from Knoxville to San Pedro Sula. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 19, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$493 | Average$633 | FlexibilityNo cancel fee | On-time71% |