HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Santo Domingo

$134+ Cheap flights from Spartanburg, SC to Santo Domingo (SDQ)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/27. Fares are subject to change and may not be available on all flights or dates of travel.
CLT — SDQ
Dec 3 — Dec 101
Wed 12/3
Wed 12/10
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Spartanburg to Santo Domingo with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheapflights Tip: The best prices from Spartanburg to Santo Domingo Las Americas are usually found in September or February, booked 82 days in advance, depart on a Tuesday or Monday and return on a Sunday

Cheap flight deals from Spartanburg to Santo Domingo

Keep the following information in mind while searching for Spartanburg to Santo Domingo flight deals. Data was last updated November 3, 2025.

Most accurate provider

Mytrip
3 stars

Most trusted provider

Mytrip
3 stars

Round-trip from

$274
(Cheapflightsfares)

One-way from

$134
(Cheapflightsfares)

Popular in

December

Cheapest in

September

Average price

$657
Provider with most accurate pricing for Charlotte Douglas-Santo Domingo Las Americas flight deals.
Search Deals
Provider most trusted by Cheapflights users for Charlotte Douglas-Santo Domingo Las Americas flights.
Search Deals
From Spartanburg to Santo Domingo Las Americas
Search Deals
One-way flight from Spartanburg to Santo Domingo Las Americas
Search Deals
Highest demand for flights based on searches. 12% potential increase in price ($77 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($15 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in November 2025
Search Deals

Find flight deals from Spartanburg to Santo Domingo

Cheapest flights from Spartanburg to Santo Domingo
Explore the most affordable flight options available from Spartanburg to Santo Domingo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 3, 2025.

This Kiwi.com deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/23:42 pmCLT - SDQ
1 stop23h 47mMultiple Airlines
Tue 12/94:21 pmSDQ - CLT
1 stop8h 38mMultiple Airlines
Deal found 11/2$330
This Mytrip deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/17:30 amCLT - SDQ
1 stop7h 00mSpirit Airlines
Mon 12/84:21 pmSDQ - CLT
1 stop8h 38mSpirit Airlines
Deal found 11/1$331
This Kiwi.com deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/15:59 pmCLT - SDQ
1 stop20h 31mMultiple Airlines
Mon 12/810:19 amSDQ - CLT
1 stop27h 22mMultiple Airlines
Deal found 11/1$341
This Mytrip deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/111:57 pmCLT - SDQ
1 stop6h 48mMultiple Airlines
Mon 12/154:21 pmSDQ - CLT
1 stop8h 38mMultiple Airlines
Deal found 11/2$343
This Kiwi.com deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/128:54 amCLT - SDQ
1 stop25h 57mMultiple Airlines
Tue 12/164:21 pmSDQ - CLT
1 stop8h 38mMultiple Airlines
Deal found 11/2$345
This Mytrip deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/128:55 pmCLT - SDQ
2 stops13h 56mSpirit Airlines
Tue 12/164:21 pmSDQ - CLT
1 stop8h 38mSpirit Airlines
Deal found 11/2$357
This Kiwi.com deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/127:59 pmCLT - SDQ
1 stop24h 46mMultiple Airlines
Mon 11/1710:19 amSDQ - CLT
1 stop12h 38mMultiple Airlines
Deal found 11/1$361
This Kiwi.com deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/710:42 pmCLT - SDQ
1 stop22h 03mMultiple Airlines
Fri 11/1410:19 amSDQ - CLT
1 stop12h 38mMultiple Airlines
Deal found 11/2$365
This Kiwi.com deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/27:30 amCLT - SDQ
1 stop7h 00mSpirit Airlines
Tue 12/94:21 pmSDQ - CLT
2 stops22h 41mSpirit Airlines
Deal found 11/2$368
This Mytrip deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/111:57 pmCLT - SDQ
1 stop6h 48mMultiple Airlines
Fri 1/98:01 amSDQ - CLT
1 stop7h 47mMultiple Airlines
Deal found 11/1$370

Cheapflights Fare Finder

 
Customize your flight search to find flights from Spartanburg to Santo Domingo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 3, 2025.
Use the filters below to find and compare flights from Spartanburg to Santo Domingo that are best for you.

Fly from

Spartanburg

Fly to

Santo Domingo

Route

Depart

Return

Price

CharlotteSanto Domingo

CLT - SDQ

CLTSDQ

Charlotte Douglas

Mon 12/1

5:59 pm-3:30 pm

1 stop20h 31m

Santo Domingo Las Americas

Mon 12/8

10:19 am-12:41 pm

1 stop27h 22m

$341

CharlotteSanto Domingo

CLT - SDQ

CLTSDQ

Charlotte Douglas

Tue 1/6

9:38 pm-3:23 pm

1 stop16h 45m

Santo Domingo Las Americas

Wed 1/21

6:55 pm-12:59 am

1 stop7h 04m

$345

CharlotteSanto Domingo

CLT - SDQ

CLTSDQ

Charlotte Douglas

Wed 11/12

7:59 pm-9:45 pm

1 stop24h 46m

Santo Domingo Las Americas

Mon 11/17

4:25 pm-7:58 pm

2 stops28h 33m

$369

CharlotteSanto Domingo

CLT - SDQ

CLTSDQ

Charlotte Douglas

Sat 1/24

5:45 am-1:39 am

2 stops18h 54m

Santo Domingo Las Americas

Sat 1/31

6:55 pm-12:59 am

1 stop7h 04m

$376

CharlotteSanto Domingo

CLT - SDQ

CLTSDQ

Charlotte Douglas

Sun 12/28

9:34 pm-11:20 am

1 stop12h 46m

Santo Domingo Las Americas

Wed 12/31

3:59 am-9:39 am

1 stop6h 40m

$390

CharlotteSanto Domingo

CLT - SDQ

CLTSDQ

Charlotte Douglas

Mon 12/29

9:34 pm-11:20 am

1 stop12h 46m

Santo Domingo Las Americas

Wed 12/31

3:59 am-9:39 am

1 stop6h 40m

$401

CharlotteSanto Domingo

CLT - SDQ

CLTSDQ

Charlotte Douglas

Fri 11/7

9:38 pm-9:40 pm

2 stops23h 02m

Santo Domingo Las Americas

Fri 11/14

10:19 am-9:57 pm

1 stop12h 38m

$428

CharlotteSanto Domingo

CLT - SDQ

CLTSDQ

Charlotte Douglas

Sun 12/14

7:00 am-3:23 pm

1 stop7h 23m

Santo Domingo Las Americas

Wed 1/14

8:01 am-12:59 am

2 stops17h 58m

$434

CharlotteSanto Domingo

CLT - SDQ

CLTSDQ

Charlotte Douglas

Sat 12/27

9:34 pm-3:32 am

1 stop28h 58m

Santo Domingo Las Americas

Sun 1/11

4:19 pm-3:01 pm

2 stops23h 42m

$443

CharlotteSanto Domingo

CLT - SDQ

CLTSDQ

Charlotte Douglas

Tue 1/13

5:45 am-5:50 pm

1 stop11h 05m

Santo Domingo Las Americas

Tue 1/20

8:01 am-9:06 pm

1 stop14h 05m

$448

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/2

Showing 1-10 of 21 results
1
2
3

Best time to book a flight from Spartanburg to Santo Domingo

Have a flexible travel schedule? Discover the best time to fly to Santo Domingo from Spartanburg with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Spartanburg to Santo Domingo

How far ahead should I book a flight from Spartanburg to Santo Domingo?

Use this chart to determine the optimal time to book a round-trip flight from Spartanburg to Santo Domingo. Price data was last updated on October 31, 2025.

To ensure you get the cheapest price possible for a flight from Spartanburg to Santo Domingo, you should look to book at least 62 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.

What is the cheapest month to book a flight from Spartanburg to Santo Domingo?

Currently, January is the cheapest month in which you can book a flight from Spartanburg to Santo Domingo (average of $226). Flying from Spartanburg to Santo Domingo in December is currently the most expensive (average of $400). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SB1 to SDQ?

Find hourly flight availability from Spartanburg to Santo Domingo. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated November 3, 2025.

Unlike in the morning, when flights are generally more expensive, you can save up to 19% on flights from Spartanburg to Santo Domingo by exploring options for tickets in the afternoon.

What is the cheapest day to fly from Spartanburg to Santo Domingo?

Use this chart to determine the cheapest time to fly round-trip from Spartanburg to Santo Domingo. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Spartanburg to Santo Domingo flight should consider departing on Thursday evenings when fares are most often at their lowest. Friday at noon flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing Santo Domingo

Get insights into the airlines that provide service to Santo Domingo. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santo Domingo. Reviews last updated November 3, 2025.
See what other customers who have flown with Delta, American Airlines, and Spirit Airlines from Spartanburg to Santo Domingo have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,001 reviews

Entertainment

7.9

Food

7.3

Boarding

8.2

Overall

7.9

Comfort

7.9

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,001 reviews
Delta
7.9
Good
8,001 reviews

Entertainment

7.9

Food

7.3

Boarding

8.2

Overall

7.9

Comfort

7.9

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,036 reviews
Delta
7.9
Good
8,001 reviews

Entertainment

7.9

Food

7.3

Boarding

8.2

Overall

7.9

Comfort

7.9

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Spirit Airlines
6.3
Okay
8,114 reviews
Delta
7.9
Good
8,001 reviews

Entertainment

7.9

Food

7.3

Boarding

8.2

Overall

7.9

Comfort

7.9

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Frontier
5.8
Fair
3,117 reviews
Delta
7.9
Good
8,001 reviews

Entertainment

7.9

Food

7.3

Boarding

8.2

Overall

7.9

Comfort

7.9

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Spartanburg to Santo Domingo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Santo Domingo from Spartanburg?

    If you book a flight to Santo Domingo from Spartanburg, you will be flying to Las Americas, which is the city’s only airport. Santo Domingo Las Americas (SDQ) is located 17.5 mi from the center of Santo Domingo. There are 0 flights from Spartanburg to Las Americas per day from 4 different airlines.

  • How long is the flight from Spartanburg to Santo Domingo?

    A quick flight from Spartanburg to Santo Domingo can take about 16h 45m. Spirit Airlines provides one of the quickest options available for as low as $345. Airlines will cover a distance of 1349 mi.

  • Can I find deals for flights from Spartanburg to Santo Domingo that include hotel bookings?

    Yes. In addition to deals on Spartanburg to Santo Domingo flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Spartanburg to Santo Domingo?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Spartanburg to Santo Domingo.

  • Can I find deals for business class flights from Spartanburg to Santo Domingo?

    Yes. Cheapflights offers flight deals from Spartanburg to Santo Domingo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Spartanburg to Santo Domingo?

    Currently, January is the cheapest month in which you can book a flight from Spartanburg to Santo Domingo (average of $226). Flying from Spartanburg to Santo Domingo in December is currently the most expensive (average of $400). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Santo Domingo?

Book flights to Santo Domingo if you plan to visit one of these locations
Juan Dolio

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Spartanburg to Santo Domingo

See prices for flight routes from nearby airports that may be better suited for you.
Charlotte to Punta Cana flights
Charlotte to Santo Domingo flights
Charlotte to Puerto Plata flights
Charleston to Punta Cana flights
Savannah to Punta Cana flights
Myrtle Beach to Punta Cana flights
Charlotte to Santiago de los Caballeros flights
Greenville to Punta Cana flights
Columbia to Punta Cana flights
Greenville to Santo Domingo flights
Charleston to Santo Domingo flights
Savannah to Puerto Plata flights
Savannah to Santo Domingo flights
Myrtle Beach to Santo Domingo flights
Augusta to Punta Cana flights
Hilton Head Island to Punta Cana flights
Charleston to Santiago de los Caballeros flights
Charleston to Puerto Plata flights
Columbia to Santiago de los Caballeros flights
Myrtle Beach to Puerto Plata flights
Augusta to Santiago de los Caballeros flights
Greenville to Santiago de los Caballeros flights
Columbia to Puerto Plata flights
Charlotte to Nagua flights
Augusta to Puerto Plata flights

Top 4 airlines flying from Spartanburg to Santo Domingo

Discover the top 4 airlines that operate flights from Spartanburg to Santo Domingo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 3, 2025.
AirlineCheapestAverageFlexibilityOn-time
FrontierCheapest$260Average$317FlexibilityNo cancel feeOn-time62%
Spirit AirlinesCheapest$305Average$392FlexibilityNo cancel feeOn-time65%
DeltaCheapest$448Average$621FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$484Average$634FlexibilityNo cancel feeOn-time71%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.