What are the cheapest airlines flying from Charleston to Santiago de los Caballeros round-trip?

Currently priced at $429, Delta will fly you from Charleston to Santiago de los Caballeros and back. In addition to Delta, many other airlines offer competitively priced options for your trip. Search Cheapflights for deals from JetBlue and American Airlines - these airlines can fly you to your destination from $483 and $655, respectively. Delta is 34% cheaper than the average price of flights available within the next 90 days to this destination.

What is the cheapest day to fly from Charleston to Santiago de los Caballeros?

Travelers seeking maximum savings on their Charleston to Santiago de los Caballeros flight should consider departing on Thursday mornings when fares are most often at their lowest. Monday mornings flights should be avoided if possible as fares are typically the most expensive at this time.

In terms of precipitation, rainfall in Santiago de los Caballeros ranges from 3.0 - 11.6 inches per month. December is typically the wettest month, when rainfall can reach 11.6 in. July is typically the driest time to visit Santiago de los Caballeros when rainfall is around 3.0 in.

If weather is an important factor for your trip to Santiago de los Caballeros, use this chart to help with planning. For those seeking warmer temperatures, June is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 73.4 F).

What is the cheapest day to fly round-trip from Charleston to Santiago de los Caballeros?

Friday is generally a great day to depart. Flying on this day could help you save up to 88%.

What is the cheapest month to fly from Charleston to Santiago de los Caballeros?

Flights from Charleston to Santiago de los Caballeros lean towards being more expensive in December. Prices are generally better when you fly from Charleston to Santiago de los Caballeros in February, with the cheapest ticket starting at $371.

What is the cheapest time of day to fly from CHS to STI?

A simple way to save on the total cost of your ticket is to fly from Charleston to Santiago de los Caballeros at noon. If you’re flexible enough to do this you can expect to save up to 35% on your trip compared to booking a flight in the morning.

How can I find direct flights from Charleston to Santiago de los Caballeros?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Charleston to Santiago de los Caballeros.

Can I find deals for business class flights from Charleston to Santiago de los Caballeros?

Yes. Cheapflights offers flight deals from Charleston to Santiago de los Caballeros by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$405+ Flights from Charleston to Santiago de los Caballeros

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Cheap flight deals from Charleston to Santiago de los Caballeros

Round-trip from	$405 (Kiwi.com)
Popular in	December
Cheapest in	February
Average price	$663

From Charleston to Santiago de los Caballeros

Search Deals

Highest demand for flights based on searches. 42% potential increase in price ($494 potential increase over avg. RT price).

Search Deals

Cheapest flight prices on average. 9% potential price decrease ($56 potential savings vs. average RT price).

Search Deals

Average for round-trip flights in July 2025

Search Deals

Find flight deals from Charleston to Santiago de los Caballeros

Cheapest flights from Charleston to Santiago de los Caballeros
Explore the most affordable flight options available from Charleston to Santiago de los Caballeros. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 3, 2025.

Tue 9/162:59 pmCHS - STI

2 stops20h 05mMultiple Airlines

Thu 9/2512:10 pmSTI - CHS

1 stop6h 55mMultiple Airlines

Deal found 7/2

$405

Tue 9/166:00 amCHS - STI

1 stop6h 40mDelta

Fri 9/268:40 pmSTI - CHS

1 stop15h 27mDelta

Deal found 7/3

$429

Wed 10/227:00 pmCHS - STI

1 stop7h 16mJetBlue

Mon 11/34:41 amSTI - CHS

1 stop9h 36mJetBlue

Deal found 7/1

$483

Tue 12/168:04 pmCHS - STI

1 stop16h 21mAmerican Airlines

Fri 12/266:55 amSTI - CHS

2 stops15h 35mAmerican Airlines

Deal found 7/1

$655

Best flights from Charleston to Santiago de los Caballeros
Discover carefully curated flight deals from Charleston to Santiago de los Caballeros that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 3, 2025.

Tue 9/162:59 pmCHS - STI

2 stops20h 05mMultiple Airlines

Thu 9/2512:10 pmSTI - CHS

1 stop6h 55mMultiple Airlines

Deal found 7/2

$405

Tue 9/166:00 amCHS - STI

1 stop6h 40mDelta

Fri 9/268:40 pmSTI - CHS

1 stop15h 27mDelta

Deal found 7/3

$429

Wed 10/227:00 pmCHS - STI

1 stop7h 16mJetBlue

Mon 11/34:41 amSTI - CHS

1 stop9h 36mJetBlue

Deal found 7/1

$483

Tue 12/168:04 pmCHS - STI

1 stop16h 21mAmerican Airlines

Fri 12/266:55 amSTI - CHS

2 stops15h 35mAmerican Airlines

Deal found 7/1

$655

Last-minute flights from Charleston to Santiago de los Caballeros
Discover last-minute flight deals from Charleston to Santiago de los Caballeros. Data last updated July 3, 2025 and is based on user searches.

Sat 7/511:00 amCHS - STI

1 stop13h 52mJetBlue

Mon 7/710:38 pmSTI - CHS

1 stop11h 37mJetBlue

Deal found 7/1

$1,026

Sat 7/52:48 pmCHS - STI

2 stops19h 41mMultiple Airlines

Mon 7/711:29 amSTI - CHS

2 stops20h 59mMultiple Airlines

Deal found 7/1

$1,124

Cheapflights Fare Finder

Use the filters below to find and compare flights from Charleston to Santiago de los Caballeros that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

CharlestonSantiago de los Caballeros

CHS - STI

CHSSTI

Charleston

Tue 9/16

2:59 pm-11:04 am

2 stops20h 05m

Santiago de los Caballeros

Thu 9/25

12:10 pm-7:05 pm

1 stop6h 55m

$405

CharlestonSantiago de los Caballeros

CHS - STI

CHSSTI

Charleston

Tue 9/16

6:00 am-12:40 pm

1 stop6h 40m

Santiago de los Caballeros

Fri 9/26

8:40 pm-12:07 pm

1 stop15h 27m

$429

CharlestonSantiago de los Caballeros

CHS - STI

CHSSTI

Charleston

Wed 10/22

7:00 pm-2:16 am

1 stop7h 16m

Santiago de los Caballeros

Mon 11/3

4:41 am-1:17 pm

1 stop9h 36m

$483

CharlestonSantiago de los Caballeros

CHS - STI

CHSSTI

Charleston

Tue 12/16

8:04 pm-1:25 pm

1 stop16h 21m

Santiago de los Caballeros

Fri 12/26

6:55 am-9:30 pm

2 stops15h 35m

$655

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/2

Best time to book a flight from Charleston to Santiago de los Caballeros

Have a flexible travel schedule? Discover the best time to fly to Santiago de los Caballeros from Charleston with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Charleston to Santiago de los Caballeros

What is the cheapest month to book a flight from Charleston to Santiago de los Caballeros?

Currently, May is the cheapest month in which you can book a flight from Charleston to Santiago de los Caballeros (average of $347). Flying from Charleston to Santiago de los Caballeros in July is currently the most expensive (average of $629). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Santiago de los Caballeros

Read through reviews of airlines operating flights from Charleston to Santiago de los Caballeros, such as Delta, JetBlue, and American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.

Delta

8.0

Very good

7,982 reviews

Reviews

1 / 20

10.0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Delta

8.0

Very good

7,982 reviews

Delta

8.0

Very good

7,982 reviews

Reviews

1 / 20

10.0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

JetBlue

7.3

Good

2,916 reviews

Delta

8.0

Very good

7,982 reviews

Reviews

1 / 20

10.0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

American Airlines

7.2

Good

10,000 reviews

Delta

8.0

Very good

7,982 reviews

Reviews

1 / 20

10.0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

What are the cheapest airlines flying from Charleston to Santiago de los Caballeros round-trip?
Currently priced at $429, Delta will fly you from Charleston to Santiago de los Caballeros and back. In addition to Delta, many other airlines offer competitively priced options for your trip. Search Cheapflights for deals from JetBlue and American Airlines - these airlines can fly you to your destination from $483 and $655, respectively. Delta is 34% cheaper than the average price of flights available within the next 90 days to this destination.
Can I find deals for flights from Charleston to Santiago de los Caballeros that include hotel bookings?
Yes. In addition to deals on Charleston to Santiago de los Caballeros flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Charleston to Santiago de los Caballeros?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Charleston to Santiago de los Caballeros.
Can I find deals for business class flights from Charleston to Santiago de los Caballeros?
Yes. Cheapflights offers flight deals from Charleston to Santiago de los Caballeros by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Charleston to Santiago de los Caballeros?
Currently, May is the cheapest month in which you can book a flight from Charleston to Santiago de los Caballeros (average of $347). Flying from Charleston to Santiago de los Caballeros in July is currently the most expensive (average of $629). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Top airline flying from Charleston to Santiago de los Caballeros

Airline	Cheapest	Average	Flexibility	On-time
American Airlines	Cheapest$500	Average$775	FlexibilityNo cancel fee	On-time71%

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$405+ Cheap flights from Charleston (CHS) to Santiago de los Caballeros (STI)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/16. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Charleston to Santiago de los Caballeros with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Cheap flight deals from Charleston to Santiago de los Caballeros

Round-trip from

Popular in

Cheapest in

Average price

Find flight deals from Charleston to Santiago de los Caballeros

Cheapest flights from Charleston to Santiago de los CaballerosExplore the most affordable flight options available from Charleston to Santiago de los Caballeros. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 3, 2025.

Explore the most affordable flight options available from Charleston to Santiago de los Caballeros. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 3, 2025.

Cheapflights Fare Finder

Use the filters below to find and compare flights from Charleston to Santiago de los Caballeros that are best for you.

Best time to book a flight from Charleston to Santiago de los Caballeros

Have a flexible travel schedule? Discover the best time to fly to Santiago de los Caballeros from Charleston with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Charleston to Santiago de los Caballeros

What is the cheapest month to book a flight from Charleston to Santiago de los Caballeros?

Reviews of airlines servicing Santiago de los Caballeros

Read through reviews of airlines operating flights from Charleston to Santiago de los Caballeros, such as Delta, JetBlue, and American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from Charleston to Santiago de los Caballeros. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What are the cheapest airlines flying from Charleston to Santiago de los Caballeros round-trip?

Can I find deals for flights from Charleston to Santiago de los Caballeros that include hotel bookings?

How can I find direct flights from Charleston to Santiago de los Caballeros?

Can I find deals for business class flights from Charleston to Santiago de los Caballeros?

What is the cheapest month to book a flight from Charleston to Santiago de los Caballeros?

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Charleston to Santiago de los Caballeros

See prices for flight routes from nearby airports that may be better suited for you.

Top airline flying from Charleston to Santiago de los Caballeros

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Book with Flexibility

Travel Smart

Cheapest flights from Charleston to Santiago de los Caballeros
Explore the most affordable flight options available from Charleston to Santiago de los Caballeros. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 3, 2025.