HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Santo Domingo

$180+ Cheap flights from Greenville (GSP) to Santo Domingo (SDQ)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/5. Fares are subject to change and may not be available on all flights or dates of travel.
GSP — SDQ
Jan 17 — Jan 241
Sat 1/17
Sat 1/24
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Greenville to Santo Domingo with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Greenville to Santo Domingo

Cheapest flights from Greenville to Santo Domingo
Explore the most affordable flight options available from Greenville to Santo Domingo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 18, 2025.

This Kiwi.com deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/2511:33 amGSP - SDQ
1 stop14h 59mMultiple Airlines
Tue 12/303:59 amSDQ - GSP
1 stop12h 56mMultiple Airlines
Deal found 12/16$424
This Kiwi.com deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/268:03 pmGSP - SDQ
1 stop12h 58mMultiple Airlines
Sun 12/284:21 pmSDQ - GSP
1 stop27h 14mMultiple Airlines
Deal found 12/16$530
This Kiwi.com deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/2511:33 amGSP - SDQ
1 stop14h 59mMultiple Airlines
Mon 1/512:35 pmSDQ - GSP
1 stop7h 48mMultiple Airlines
Deal found 12/16$684
This Kiwi.com deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/314:45 pmGSP - SDQ
1 stop21h 38mMultiple Airlines
Sun 1/44:33 pmSDQ - GSP
2 stops28h 35mMultiple Airlines
Deal found 12/17$746
This American Airlines deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/255:39 amGSP - SDQ
2 stops11h 17mAmerican Airlines
Wed 12/316:00 amSDQ - GSP
2 stops14h 24mAmerican Airlines
Deal found 12/16$1,025
This American Airlines deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/317:45 amGSP - SDQ
1 stop13h 15mAmerican Airlines
Sun 1/47:13 amSDQ - GSP
1 stop11h 38mAmerican Airlines
Deal found 12/17$1,289

Find flight deals from Greenville to Santo Domingo

Discover tips and strategies to find the most affordable flight options for your journey from Greenville (GSP) to Santo Domingo (SDQ). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated December 18, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$366
(Kiwi.com)

One-way from

$180
(Kiwi.com)

Popular in

December

Cheapest in

May

Average price

$921
Provider with most accurate pricing for Greenville-Santo Domingo Las Americas flight deals.
Search Deals
Provider most trusted by Cheapflights users for Greenville-Santo Domingo Las Americas flights.
Search Deals
From Greenville to Santo Domingo Las Americas
Search Deals
One-way flight from Greenville to Santo Domingo Las Americas
Search Deals
Highest demand for flights based on searches. 3% potential increase in price ($23 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 4% potential price decrease ($27 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Greenville to Santo Domingo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 18, 2025.
Use the filters below to find and compare flights from Greenville to Santo Domingo that are best for you.

Fly from

Greenville

Fly to

Santo Domingo

Route

Depart

Return

Price

GreenvilleSanto Domingo

GSP - SDQ

GSPSDQ

Greenville

Fri 1/23

4:39 pm-2:27 pm

2 stops20h 48m

Santo Domingo Las Americas

Wed 1/28

3:32 pm-4:55 pm

1 stop26h 23m

$384

GreenvilleSanto Domingo

GSP - SDQ

GSPSDQ

Greenville

Wed 2/4

5:40 am-2:21 pm

1 stop7h 41m

Santo Domingo Las Americas

Mon 2/9

3:46 pm-11:50 pm

1 stop9h 04m

$478

GreenvilleSanto Domingo

GSP - SDQ

GSPSDQ

Greenville

Fri 1/23

11:00 am-10:39 pm

2 stops10h 39m

Santo Domingo Las Americas

Wed 1/28

1:23 pm-11:36 pm

2 stops11h 13m

$482

GreenvilleSanto Domingo

GSP - SDQ

GSPSDQ

Greenville

Wed 2/4

6:00 am-3:45 pm

2 stops8h 45m

Santo Domingo Las Americas

Mon 2/9

6:00 am-7:12 pm

2 stops14h 12m

$482

GreenvilleSanto Domingo

GSP - SDQ

GSPSDQ

Greenville

Sun 3/29

7:12 pm-9:00 am

1 stop13h 48m

Santo Domingo Las Americas

Sun 4/5

10:00 am-6:42 pm

1 stop8h 42m

$483

GreenvilleSanto Domingo

GSP - SDQ

GSPSDQ

Greenville

Sun 3/29

2:57 pm-9:41 am

1 stop18h 44m

Santo Domingo Las Americas

Sun 4/5

3:39 pm-3:27 pm

2 stops23h 48m

$550

GreenvilleSanto Domingo

GSP - SDQ

GSPSDQ

Greenville

Sun 2/1

6:20 am-3:06 pm

1 stop7h 46m

Santo Domingo Las Americas

Thu 2/5

2:53 pm-11:48 pm

1 stop9h 55m

$628

GreenvilleSanto Domingo

GSP - SDQ

GSPSDQ

Greenville

Sun 4/5

6:24 pm-9:00 am

2 stops14h 36m

Santo Domingo Las Americas

Fri 4/10

5:55 am-7:10 pm

2 stops13h 15m

$682

GreenvilleSanto Domingo

GSP - SDQ

GSPSDQ

Greenville

Wed 12/31

4:45 pm-3:23 pm

1 stop21h 38m

Santo Domingo Las Americas

Sun 1/4

4:33 pm-8:08 pm

2 stops28h 35m

$746

GreenvilleSanto Domingo

GSP - SDQ

GSPSDQ

Greenville

Mon 1/5

8:58 pm-11:12 am

2 stops37h 14m

$180

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/16

Showing 1-10 of 15 results
1
2

Compare providers for flights from Greenville to Santo Domingo

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Greenville to Santo Domingo in December.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
eDreamsPrice Accuracy3 starsTrust Score*3 stars
OvagoPrice Accuracy2 starsTrust Score*2 stars
AranGrantPrice Accuracy2 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Greenville-Santo Domingo flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Greenville-Santo Domingo flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Greenville-Santo Domingo flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Greenville-Santo Domingo flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Greenville-Santo Domingo flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Greenville to Santo Domingo

Have a flexible travel schedule? Discover the best time to fly to Santo Domingo from Greenville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Greenville to Santo Domingo

What is the cheapest month to book a flight from Greenville to Santo Domingo?

Currently, January is the cheapest month in which you can book a flight from Greenville to Santo Domingo (average of $224). Flying from Greenville to Santo Domingo in December is currently the most expensive (average of $365). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Greenville to Santo Domingo?

Reviews of airlines servicing Santo Domingo

Get insights into the airlines that provide service to Santo Domingo. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santo Domingo. Reviews last updated December 18, 2025.
Read through reviews of airlines operating flights from Greenville to Santo Domingo, such as Delta and American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,005 reviews

Entertainment

7.9

Overall

7.9

Food

7.3

Crew

8.5

Comfort

7.9

Boarding

8.1

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,005 reviews
Delta
7.9
Good
8,005 reviews

Entertainment

7.9

Overall

7.9

Food

7.3

Crew

8.5

Comfort

7.9

Boarding

8.1

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,054 reviews
Delta
7.9
Good
8,005 reviews

Entertainment

7.9

Overall

7.9

Food

7.3

Crew

8.5

Comfort

7.9

Boarding

8.1

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Greenville to Santo Domingo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Greenville to Santo Domingo?

    Airlines like Delta and American Airlines fly from Greenville to Santo Domingo in about 7h 41m. The time it takes to get you to your destination can typically vary by up to 2h 58m. There are 1373 mi between Greenville and Santo Domingo. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines flying from Greenville to Santo Domingo round-trip?

    Our cheapest airline available from Greenville to Santo Domingo is Delta. Our recent data shows that you can find tickets from as low as $484 on this airline. An additional option worth looking into is American Airlines, starting at $511. Delta is priced at 22% lower than the current average price of a flight leaving 3 months from now.

  • Can I find deals for flights from Greenville to Santo Domingo that include hotel bookings?

    Yes. In addition to deals on Greenville to Santo Domingo flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Greenville to Santo Domingo?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Greenville to Santo Domingo.

  • Can I find deals for business class flights from Greenville to Santo Domingo?

    Yes. Cheapflights offers flight deals from Greenville to Santo Domingo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Greenville to Santo Domingo?

    Currently, January is the cheapest month in which you can book a flight from Greenville to Santo Domingo (average of $224). Flying from Greenville to Santo Domingo in December is currently the most expensive (average of $365). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Santo Domingo?

Book flights to Santo Domingo if you plan to visit one of these locations
Juan Dolio

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Greenville to Santo Domingo

See prices for flight routes from nearby airports that may be better suited for you.
Charlotte to Punta Cana flights
Charlotte to Santo Domingo flights
Charleston to Punta Cana flights
Charlotte to Puerto Plata flights
Charlotte to Santiago de los Caballeros flights
Myrtle Beach to Punta Cana flights
Savannah to Punta Cana flights
Greenville to Punta Cana flights
Columbia to Punta Cana flights
Charleston to Santo Domingo flights
Augusta to Punta Cana flights
Savannah to Puerto Plata flights
Charleston to Santiago de los Caballeros flights
Charleston to Puerto Plata flights
Columbia to Santiago de los Caballeros flights
Savannah to Santo Domingo flights
Columbia to Puerto Plata flights
Greenville to Santiago de los Caballeros flights
Myrtle Beach to Puerto Plata flights
Augusta to Santiago de los Caballeros flights
Myrtle Beach to Santo Domingo flights
Charlotte to Nagua flights
Hilton Head Island to Punta Cana flights
Augusta to Puerto Plata flights

Top 2 airlines flying from Greenville to Santo Domingo

Discover the top 2 airlines that operate flights from Greenville to Santo Domingo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 18, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$484Average$513FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$511Average$567FlexibilityNo cancel feeOn-time71%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.
Site
©2025 Cheapflights