What are the cheapest airlines flying from Fort Myers to Santo Domingo round-trip?

Our cheapest airline available from Fort Myers to Santo Domingo is Spirit Airlines. Our recent data shows that you can find tickets from as low as $452 on this airline. Additional options worth looking into are JetBlue and American Airlines, starting at $465 and $489 round-trip. You may be able to fly from Fort Myers to Santo Domingo for 28% less than the average price by searching for these airlines.

What is the cheapest month to book a flight from Fort Myers to Santo Domingo?

Currently, January is the cheapest month in which you can book a flight from Fort Myers to Santo Domingo (average of $362). Flying from Fort Myers to Santo Domingo in December is currently the most expensive (average of $583). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest day to fly from Fort Myers to Santo Domingo?

Travelers seeking maximum savings on their Fort Myers to Santo Domingo flight should consider departing on Friday mornings when fares are most often at their lowest. Sunday mornings flights should be avoided if possible as fares are typically the most expensive at this time.

In terms of precipitation, rainfall in Santo Domingo ranges from 1.6 - 6.7 inches per month. May is typically the wettest month, when rainfall can reach 6.7 in. February is typically the driest time to visit Santo Domingo when rainfall is around 1.6 in.

If weather is an important factor for your trip to Santo Domingo, use this chart to help with planning. For those seeking warmer temperatures, June is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 75.2 F).

What is the cheapest day to fly round-trip from Fort Myers to Santo Domingo?

It’s generally more expensive to depart on a Friday, if you have to leave on this day you can still search on Cheapflights to find great options that meet your needs.

What is the cheapest month to fly from Fort Myers to Santo Domingo?

Flights from Fort Myers to Santo Domingo lean towards being more expensive in August. Prices are generally better when you fly from Fort Myers to Santo Domingo in February, with the cheapest ticket starting at $429.

What is the cheapest time of day to fly from RSW to SDQ?

A simple way to save on the total cost of your ticket is to fly from Fort Myers to Santo Domingo in the afternoon. If you’re flexible enough to do this you can expect to save up to 6% on your trip compared to booking a flight at noon.

Can I find deals for flights from Fort Myers to Santo Domingo that include hotel bookings?

Yes. In addition to deals on Fort Myers to Santo Domingo flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Fort Myers to Santo Domingo?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Fort Myers to Santo Domingo.

Can I find deals for business class flights from Fort Myers to Santo Domingo?

Yes. Cheapflights offers flight deals from Fort Myers to Santo Domingo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$452+ Flights from Fort Myers to Santo Domingo

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Cheap flight deals from Fort Myers to Santo Domingo

Round-trip from	$452 (Mytrip)
Popular in	August
Cheapest in	February
Average price	$738

From Fort Myers SW Florida Intl to Santo Domingo Las Americas

Search Deals

Highest demand for flights based on searches. 11% potential increase in price ($83 potential increase over avg. RT price).

Search Deals

Cheapest flight prices on average. 5% potential price decrease ($33 potential savings vs. average RT price).

Search Deals

Average for round-trip flights in July 2025

Search Deals

Find flight deals from Fort Myers to Santo Domingo

Cheapest flights from Fort Myers to Santo Domingo
Explore the most affordable flight options available from Fort Myers to Santo Domingo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 29, 2025.

Thu 9/185:20 pmRSW - SDQ

2 stops22h 40mSpirit Airlines

Sat 9/203:47 pmSDQ - RSW

2 stops16h 58mSpirit Airlines

Deal found 7/28

$452

Tue 9/26:00 amRSW - SDQ

1 stop16h 05mJetBlue

Tue 9/98:10 amSDQ - RSW

1 stop9h 34mJetBlue

Deal found 7/28

$465

Fri 9/1211:14 amRSW - SDQ

2 stops9h 16mAmerican Airlines

Mon 9/152:35 pmSDQ - RSW

2 stops21h 44mAmerican Airlines

Deal found 7/28

$489

Thu 9/185:20 pmRSW - SDQ

2 stops22h 40mMultiple Airlines

Fri 9/192:05 amSDQ - RSW

2 stops17h 25mMultiple Airlines

Deal found 7/28

$601

Fri 9/125:35 amRSW - SDQ

2 stops12h 24mDelta

Mon 9/152:50 pmSDQ - RSW

1 stop9h 45mDelta

Deal found 7/28

$689

Best flights from Fort Myers to Santo Domingo
Discover carefully curated flight deals from Fort Myers to Santo Domingo that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 29, 2025.

Thu 9/185:20 pmRSW - SDQ

2 stops22h 40mSpirit Airlines

Sat 9/203:47 pmSDQ - RSW

2 stops16h 58mSpirit Airlines

Deal found 7/28

$452

Tue 9/26:00 amRSW - SDQ

1 stop16h 05mJetBlue

Tue 9/98:10 amSDQ - RSW

1 stop9h 34mJetBlue

Deal found 7/28

$465

Fri 9/1211:14 amRSW - SDQ

2 stops9h 16mAmerican Airlines

Mon 9/152:35 pmSDQ - RSW

2 stops21h 44mAmerican Airlines

Deal found 7/28

$489

Thu 9/185:20 pmRSW - SDQ

2 stops22h 40mMultiple Airlines

Fri 9/192:05 amSDQ - RSW

2 stops17h 25mMultiple Airlines

Deal found 7/28

$601

Fri 9/125:35 amRSW - SDQ

2 stops12h 24mDelta

Mon 9/152:50 pmSDQ - RSW

1 stop9h 45mDelta

Deal found 7/28

$689

Last-minute flights from Fort Myers to Santo Domingo
Discover last-minute flight deals from Fort Myers to Santo Domingo. Data last updated July 29, 2025 and is based on user searches.

Mon 8/44:07 pmRSW - SDQ

2 stops21h 21mAmerican Airlines

Mon 8/112:35 pmSDQ - RSW

2 stops19h 37mAmerican Airlines

Deal found 7/28

$529

Mon 8/43:45 pmRSW - SDQ

2 stops24h 02mSpirit Airlines

Mon 8/1112:46 pmSDQ - RSW

3 stops31h 43mSpirit Airlines

Deal found 7/28

$634

Mon 8/46:00 amRSW - SDQ

2 stops21h 49mJetBlue

Mon 8/1111:05 pmSDQ - RSW

1 stop21h 16mJetBlue

Deal found 7/28

$687

Tue 8/266:00 amRSW - SDQ

1 stop15h 40mJetBlue

Mon 9/12:05 amSDQ - RSW

1 stop10h 01mJetBlue

Deal found 7/27

$640

Cheapflights Fare Finder

Use the filters below to find and compare flights from Fort Myers to Santo Domingo that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Fort MyersSanto Domingo

RSW - SDQ

RSWSDQ

Fort Myers SW Florida Intl

Thu 9/18

5:20 pm-4:00 pm

2 stops22h 40m

Santo Domingo Las Americas

Sat 9/20

3:47 pm-8:45 am

2 stops16h 58m

$452

Fort MyersSanto Domingo

RSW - SDQ

RSWSDQ

Fort Myers SW Florida Intl

Tue 9/2

6:00 am-10:05 pm

1 stop16h 05m

Santo Domingo Las Americas

Tue 9/9

8:10 am-5:44 pm

1 stop9h 34m

$465

Fort MyersSanto Domingo

RSW - SDQ

RSWSDQ

Fort Myers SW Florida Intl

Fri 9/12

11:14 am-8:30 pm

2 stops9h 16m

Santo Domingo Las Americas

Mon 9/15

2:35 pm-12:19 pm

2 stops21h 44m

$489

Fort MyersSanto Domingo

RSW - SDQ

RSWSDQ

Fort Myers SW Florida Intl

Thu 9/18

5:20 pm-4:00 pm

2 stops22h 40m

Santo Domingo Las Americas

Fri 9/19

2:05 am-7:30 pm

2 stops17h 25m

$601

Fort MyersSanto Domingo

RSW - SDQ

RSWSDQ

Fort Myers SW Florida Intl

Fri 9/12

5:35 am-5:59 pm

2 stops12h 24m

Santo Domingo Las Americas

Mon 9/15

2:50 pm-12:35 am

1 stop9h 45m

$689

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/28

Best time to book a flight from Fort Myers to Santo Domingo

Have a flexible travel schedule? Discover the best time to fly to Santo Domingo from Fort Myers with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Reviews of airlines servicing Santo Domingo

Get a feel of what it's like to fly with Delta, JetBlue, and American Airlines from Fort Myers to Santo Domingo by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.

Delta

8.0

Very good

7,977 reviews

Reviews

1 / 20

6.0

Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.

Delta

8.0

Very good

7,977 reviews

Delta

8.0

Very good

7,977 reviews

Reviews

1 / 20

6.0

Good

pilar,May 2025

RSW - ATL

JetBlue

7.3

Good

2,913 reviews

Delta

8.0

Very good

7,977 reviews

Reviews

1 / 20

6.0

Good

pilar,May 2025

RSW - ATL

American Airlines

7.2

Good

10,000 reviews

Delta

8.0

Very good

7,977 reviews

Reviews

1 / 20

6.0

Good

pilar,May 2025

RSW - ATL

Spirit Airlines

6.3

Okay

8,040 reviews

Delta

8.0

Very good

7,977 reviews

Reviews

1 / 20

6.0

Good

pilar,May 2025

RSW - ATL

Related info for your journey

What are the cheapest airlines flying from Fort Myers to Santo Domingo round-trip?
Our cheapest airline available from Fort Myers to Santo Domingo is Spirit Airlines. Our recent data shows that you can find tickets from as low as $452 on this airline. Additional options worth looking into are JetBlue and American Airlines, starting at $465 and $489 round-trip. You may be able to fly from Fort Myers to Santo Domingo for 28% less than the average price by searching for these airlines.
Can I find deals for flights from Fort Myers to Santo Domingo that include hotel bookings?
Yes. In addition to deals on Fort Myers to Santo Domingo flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Fort Myers to Santo Domingo?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Fort Myers to Santo Domingo.
Can I find deals for business class flights from Fort Myers to Santo Domingo?
Yes. Cheapflights offers flight deals from Fort Myers to Santo Domingo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Fort Myers to Santo Domingo?
Currently, January is the cheapest month in which you can book a flight from Fort Myers to Santo Domingo (average of $362). Flying from Fort Myers to Santo Domingo in December is currently the most expensive (average of $583). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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$452+ Cheap flights from Fort Myers (RSW) to Santo Domingo (SDQ)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/18. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Fort Myers to Santo Domingo with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Cheap flight deals from Fort Myers to Santo Domingo

Round-trip from

Popular in

Cheapest in

Average price

Find flight deals from Fort Myers to Santo Domingo

Cheapest flights from Fort Myers to Santo DomingoExplore the most affordable flight options available from Fort Myers to Santo Domingo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 29, 2025.

Explore the most affordable flight options available from Fort Myers to Santo Domingo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 29, 2025.

Cheapflights Fare Finder

Use the filters below to find and compare flights from Fort Myers to Santo Domingo that are best for you.

Best time to book a flight from Fort Myers to Santo Domingo

Have a flexible travel schedule? Discover the best time to fly to Santo Domingo from Fort Myers with our price prediction graph.

Reviews of airlines servicing Santo Domingo

Get a feel of what it's like to fly with Delta, JetBlue, and American Airlines from Fort Myers to Santo Domingo by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from Fort Myers to Santo Domingo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What are the cheapest airlines flying from Fort Myers to Santo Domingo round-trip?

Can I find deals for flights from Fort Myers to Santo Domingo that include hotel bookings?

How can I find direct flights from Fort Myers to Santo Domingo?

Can I find deals for business class flights from Fort Myers to Santo Domingo?

What is the cheapest month to book a flight from Fort Myers to Santo Domingo?

Traveling to a place near Santo Domingo?

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Alternative routes for Fort Myers to Santo Domingo

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Travel Smart

Cheapest flights from Fort Myers to Santo Domingo
Explore the most affordable flight options available from Fort Myers to Santo Domingo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 29, 2025.