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Santo Domingo

$133+ Cheap flights from Charleston (CHS) to Santo Domingo (SDQ)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/7. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — SDQ
Nov 27 — Dec 41
Thu 11/27
Thu 12/4
1 adult, Economy
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Cheap flight deals from Charleston to Santo Domingo

Discover tips and strategies to find the most affordable flight options for your journey from Charleston (CHS) to Santo Domingo (SDQ). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 28, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$275
(Cheapflightsfares)

One-way from

$133
(Spirit)

Popular in

December

Cheapest in

November

Average price

$531
Provider with most accurate pricing for Charleston-Santo Domingo Las Americas flight deals.
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Provider most trusted by Cheapflights users for Charleston-Santo Domingo Las Americas flights.
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From Charleston to Santo Domingo Las Americas
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One-way flight from Charleston to Santo Domingo Las Americas
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High demand for flights, 6% potential price rise
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Cheapest flight prices on average. 3% potential price decrease ($20 potential savings vs. average RT price).
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Average for round-trip flights in October 2025
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Find flight deals from Charleston to Santo Domingo

Cheapest flights from Charleston to Santo Domingo
Explore the most affordable flight options available from Charleston to Santo Domingo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 28, 2025.

This Cheapflightsfares deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/256:50 amCHS - SDQ
1 stop7h 40mSpirit Airlines
Mon 12/14:35 pmSDQ - CHS
1 stop6h 30mSpirit Airlines
Deal found 10/27$275
This American Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/86:09 pmCHS - SDQ
1 stop20h 36mAmerican Airlines
Tue 11/113:05 pmSDQ - CHS
1 stop18h 37mAmerican Airlines
Deal found 10/27$317
This Delta deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/812:59 pmCHS - SDQ
2 stops11h 28mDelta
Tue 11/116:45 amSDQ - CHS
2 stops11h 38mDelta
Deal found 10/27$322
This American Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/255:15 amCHS - SDQ
2 stops9h 30mAmerican Airlines
Mon 12/16:14 pmSDQ - CHS
1 stop15h 29mAmerican Airlines
Deal found 10/27$407
This Expedia deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/82:15 pmCHS - SDQ
1 stop7h 13mJetBlue
Mon 11/104:10 amSDQ - CHS
1 stop10h 09mJetBlue
Deal found 10/27$473
This Kiwi.com deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/252:59 pmCHS - SDQ
1 stop11h 33mMultiple Airlines
Sat 1/1010:56 amSDQ - CHS
1 stop22h 37mMultiple Airlines
Deal found 10/26$478
This JetBlue deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/258:24 amCHS - SDQ
1 stop4h 58mJetBlue
Sun 11/304:10 amSDQ - CHS
1 stop15h 04mJetBlue
Deal found 10/27$572
This KAYAK deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/236:13 pmCHS - SDQ
2 stops20h 17mSpirit Airlines
Sun 11/304:35 pmSDQ - CHS
1 stop6h 30mSpirit Airlines
Deal found 10/26$601
This JetBlue deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/236:05 pmCHS - SDQ
1 stop7h 52mJetBlue
Sun 11/3011:54 pmSDQ - CHS
1 stop12h 27mJetBlue
Deal found 10/26$627

Cheapflights Fare Finder

 
Customize your flight search to find flights from Charleston to Santo Domingo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 28, 2025.
Use the filters below to find and compare flights from Charleston to Santo Domingo that are best for you.

Fly from

Charleston

Fly to

Santo Domingo

Route

Depart

Return

Price

CharlestonSanto Domingo

CHS - SDQ

CHSSDQ

Charleston

Sat 11/8

6:09 pm-3:45 pm

1 stop20h 36m

Santo Domingo Las Americas

Tue 11/11

3:05 pm-8:42 am

1 stop18h 37m

$317

CharlestonSanto Domingo

CHS - SDQ

CHSSDQ

Charleston

Sat 11/8

12:59 pm-1:27 am

2 stops11h 28m

Santo Domingo Las Americas

Tue 11/11

6:45 am-5:23 pm

2 stops11h 38m

$322

CharlestonSanto Domingo

CHS - SDQ

CHSSDQ

Charleston

Tue 11/25

5:15 am-3:45 pm

2 stops9h 30m

Santo Domingo Las Americas

Mon 12/1

6:14 pm-8:43 am

1 stop15h 29m

$407

CharlestonSanto Domingo

CHS - SDQ

CHSSDQ

Charleston

Tue 3/3

6:00 am-3:06 pm

1 stop8h 06m

Santo Domingo Las Americas

Thu 3/5

4:18 pm-11:24 pm

1 stop8h 06m

$444

CharlestonSanto Domingo

CHS - SDQ

CHSSDQ

Charleston

Tue 3/3

12:05 pm-10:33 pm

1 stop9h 28m

Santo Domingo Las Americas

Wed 3/4

2:35 am-11:19 am

1 stop9h 44m

$473

CharlestonSanto Domingo

CHS - SDQ

CHSSDQ

Charleston

Thu 12/25

2:59 pm-3:32 am

1 stop11h 33m

Santo Domingo Las Americas

Sat 1/10

10:56 am-8:33 am

1 stop22h 37m

$478

CharlestonSanto Domingo

CHS - SDQ

CHSSDQ

Charleston

Tue 3/3

12:15 pm-11:59 pm

2 stops10h 44m

Santo Domingo Las Americas

Thu 3/5

8:00 pm-1:45 pm

2 stops18h 45m

$506

CharlestonSanto Domingo

CHS - SDQ

CHSSDQ

Charleston

Fri 11/7

7:00 am-3:30 pm

1 stop7h 30m

$133

CharlestonSanto Domingo

CHS - SDQ

CHSSDQ

Charleston

Tue 12/2

6:50 am-3:30 pm

1 stop7h 40m

$146

CharlestonSanto Domingo

CHS - SDQ

CHSSDQ

Charleston

Sat 11/8

12:50 pm-1:27 am

1 stop11h 37m

$147

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/27

Showing 1-10 of 18 results
1
2

Compare providers for flights from Charleston to Santo Domingo

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Charleston to Santo Domingo in October.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
eDreamsPrice Accuracy3 starsTrust Score*3 stars
AranGrantPrice Accuracy2 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Charleston-Santo Domingo flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Charleston-Santo Domingo flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Charleston-Santo Domingo flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Charleston-Santo Domingo flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Charleston-Santo Domingo flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Charleston to Santo Domingo

Have a flexible travel schedule? Discover the best time to fly to Santo Domingo from Charleston with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Charleston to Santo Domingo

What is the cheapest month to book a flight from Charleston to Santo Domingo?

Currently, November is the cheapest month in which you can book a flight from Charleston to Santo Domingo (average of $164). Flying from Charleston to Santo Domingo in June is currently the most expensive (average of $493). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from CHS to SDQ?

Find hourly flight availability from Charleston to Santo Domingo. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 28, 2025.

One of the essential ways to save on airfare from Charleston to Santo Domingo is to remain as flexible as possible. Flights that are in the afternoon tend to be the most expensive. A flight at noon could potentially save you up to 59% on airfare.

Reviews of airlines servicing Santo Domingo

Get insights into the airlines that provide service to Santo Domingo. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santo Domingo. Reviews last updated October 28, 2025.
See what other customers who have flown with Delta and American Airlines from Charleston to Santo Domingo have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
7,994 reviews

Comfort

7.9

Boarding

8.2

Crew

8.5

Food

7.3

Overall

7.9

Entertainment

7.9

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
Delta
7.9
Good
7,994 reviews
Delta
7.9
Good
7,994 reviews

Comfort

7.9

Boarding

8.2

Crew

8.5

Food

7.3

Overall

7.9

Entertainment

7.9

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
American Airlines
7.2
Good
11,032 reviews
Delta
7.9
Good
7,994 reviews

Comfort

7.9

Boarding

8.2

Crew

8.5

Food

7.3

Overall

7.9

Entertainment

7.9

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.

Related info for your journey

Find useful and relevant information for your journey from Charleston to Santo Domingo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Charleston to Santo Domingo?

    For as low as $444, American Airlines can have you in Santo Domingo from Charleston in 8h 06m. Charleston and Santo Domingo are separated by a distance of 1187 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines flying from Charleston to Santo Domingo round-trip?

    American Airlines, at $358, was found to be the cheapest airline from Charleston to Santo Domingo. An alternate airline flying to your destination would be Delta. You may be able to fly from Charleston to Santo Domingo for 34% less than the average price by searching for these airlines.

  • What are the cheapest airlines to fly from Charleston to Santo Domingo one-way?

    To fly one-way, consider booking your trip with Spirit Airlines, which is currently one of the cheapest options available, starting at $133. Delta flights start at $147 while deals on American Airlines start at $147 one-way.

  • Can I find deals for flights from Charleston to Santo Domingo that include hotel bookings?

    Yes. In addition to deals on Charleston to Santo Domingo flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Charleston to Santo Domingo?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Charleston to Santo Domingo.

  • Can I find deals for business class flights from Charleston to Santo Domingo?

    Yes. Cheapflights offers flight deals from Charleston to Santo Domingo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Charleston to Santo Domingo?

    Currently, November is the cheapest month in which you can book a flight from Charleston to Santo Domingo (average of $164). Flying from Charleston to Santo Domingo in June is currently the most expensive (average of $493). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Santo Domingo?

Book flights to Santo Domingo if you plan to visit one of these locations
Juan Dolio

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Top 2 airlines flying from Charleston to Santo Domingo

Discover the top 2 airlines that operate flights from Charleston to Santo Domingo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 28, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$358Average$505FlexibilityNo cancel feeOn-time71%
DeltaCheapest$420Average$597FlexibilityNo cancel feeOn-timeN/A

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