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Santo Domingo

$136+ Cheap flights from Charleston (CHS) to Santo Domingo (SDQ)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/17. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — SDQ
Jan 11 — Jan 181
Sun 1/11
Sun 1/18
1 adult, Economy
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Cheap flight deals from Charleston to Santo Domingo

Cheapest flights from Charleston to Santo Domingo
Explore the most affordable flight options available from Charleston to Santo Domingo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 12, 2025.

This Kiwi.com deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/2210:18 pmCHS - SDQ
1 stop27h 36mMultiple Airlines
Mon 1/124:27 pmSDQ - CHS
2 stops17h 11mMultiple Airlines
Deal found 12/11$559
This Kiwi.com deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/302:59 pmCHS - SDQ
1 stop11h 33mMultiple Airlines
Thu 1/13:59 amSDQ - CHS
1 stop18h 24mMultiple Airlines
Deal found 12/10$563
This JetBlue deal was found by Cheapflights users on 12/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/2511:16 amCHS - SDQ
1 stop13h 07mJetBlue
Sat 1/106:10 amSDQ - CHS
1 stop7h 30mJetBlue
Deal found 12/9$755
This American Airlines deal was found by Cheapflights users on 12/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/256:44 amCHS - SDQ
2 stops10h 12mAmerican Airlines
Sat 1/106:29 pmSDQ - CHS
1 stop15h 14mAmerican Airlines
Deal found 12/9$861
This American Airlines deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/308:08 pmCHS - SDQ
2 stops12h 59mAmerican Airlines
Fri 1/26:00 amSDQ - CHS
2 stops9h 18mAmerican Airlines
Deal found 12/10$1,298
This Delta deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/225:30 amCHS - SDQ
2 stops11h 53mDelta
Mon 1/127:31 amSDQ - CHS
2 stops14h 24mDelta
Deal found 12/11$1,549

Find flight deals from Charleston to Santo Domingo

Discover tips and strategies to find the most affordable flight options for your journey from Charleston (CHS) to Santo Domingo (SDQ). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated December 12, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$310
(Kiwi.com)

One-way from

$136
(Flysmarter)

Popular in

April

Cheapest in

November

Average price

$615
Provider with most accurate pricing for Charleston-Santo Domingo Las Americas flight deals.
Search Deals
Provider most trusted by Cheapflights users for Charleston-Santo Domingo Las Americas flights.
Search Deals
From Charleston to Santo Domingo Las Americas
Search Deals
One-way flight from Charleston to Santo Domingo Las Americas
Search Deals
Highest demand for flights based on searches. 13% potential increase in price ($82 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($10 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Charleston to Santo Domingo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 12, 2025.
Use the filters below to find and compare flights from Charleston to Santo Domingo that are best for you.

Fly from

Charleston

Fly to

Santo Domingo

Route

Depart

Return

Price

CharlestonSanto Domingo

CHS - SDQ

CHSSDQ

Charleston

Wed 1/21

6:00 am-2:00 pm

1 stop7h 00m

Santo Domingo Las Americas

Mon 1/26

6:29 pm-11:58 pm

1 stop6h 29m

$318

CharlestonSanto Domingo

CHS - SDQ

CHSSDQ

Charleston

Wed 1/21

6:00 am-3:45 pm

1 stop8h 45m

Santo Domingo Las Americas

Tue 1/27

6:00 am-6:40 pm

1 stop13h 40m

$318

CharlestonSanto Domingo

CHS - SDQ

CHSSDQ

Charleston

Sun 1/25

6:10 am-3:45 pm

2 stops8h 35m

Santo Domingo Las Americas

Sun 2/1

6:29 pm-9:48 am

2 stops16h 19m

$327

CharlestonSanto Domingo

CHS - SDQ

CHSSDQ

Charleston

Sun 1/25

10:10 am-7:49 pm

1 stop8h 39m

Santo Domingo Las Americas

Thu 1/29

9:50 pm-9:20 am

1 stop12h 30m

$387

CharlestonSanto Domingo

CHS - SDQ

CHSSDQ

Charleston

Thu 3/26

7:39 pm-3:31 am

1 stop7h 52m

Santo Domingo Las Americas

Sun 3/29

5:01 am-6:43 pm

1 stop13h 42m

$407

CharlestonSanto Domingo

CHS - SDQ

CHSSDQ

Charleston

Tue 3/17

7:39 pm-3:31 am

1 stop7h 52m

$136

CharlestonSanto Domingo

CHS - SDQ

CHSSDQ

Charleston

Tue 3/17

5:20 am-5:35 pm

2 stops12h 15m

$149

CharlestonSanto Domingo

CHS - SDQ

CHSSDQ

Charleston

Tue 5/5

6:00 am-1:36 pm

1 stop7h 36m

$149

CharlestonSanto Domingo

CHS - SDQ

CHSSDQ

Charleston

Fri 5/15

3:30 pm-3:03 am

1 stop11h 33m

$149

CharlestonSanto Domingo

CHS - SDQ

CHSSDQ

Charleston

Tue 12/30

8:08 pm-10:07 am

2 stops12h 59m

$239

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/11

Showing 1-10 of 14 results
1
2

Compare providers for flights from Charleston to Santo Domingo

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Charleston to Santo Domingo in December.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
eDreamsPrice Accuracy3 starsTrust Score*3 stars
AranGrantPrice Accuracy2 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Charleston-Santo Domingo flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Charleston-Santo Domingo flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Charleston-Santo Domingo flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Charleston-Santo Domingo flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Charleston-Santo Domingo flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Charleston to Santo Domingo

Have a flexible travel schedule? Discover the best time to fly to Santo Domingo from Charleston with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Charleston to Santo Domingo

What is the cheapest month to book a flight from Charleston to Santo Domingo?

Currently, January is the cheapest month in which you can book a flight from Charleston to Santo Domingo (average of $340). Flying from Charleston to Santo Domingo in June is currently the most expensive (average of $528). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from CHS to SDQ?

Find hourly flight availability from Charleston to Santo Domingo. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 12, 2025.

One of the essential ways to save on airfare from Charleston to Santo Domingo is to remain as flexible as possible. Flights that are in the afternoon tend to be the most expensive. A flight at noon could potentially save you up to 59% on airfare.

Reviews of airlines servicing Santo Domingo

Get insights into the airlines that provide service to Santo Domingo. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santo Domingo. Reviews last updated December 12, 2025.
See what other customers who have flown with Delta and American Airlines from Charleston to Santo Domingo have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,008 reviews

Food

7.3

Boarding

8.1

Comfort

7.9

Overall

7.9

Entertainment

7.9

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,008 reviews
Delta
7.9
Good
8,008 reviews

Food

7.3

Boarding

8.1

Comfort

7.9

Overall

7.9

Entertainment

7.9

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,050 reviews
Delta
7.9
Good
8,008 reviews

Food

7.3

Boarding

8.1

Comfort

7.9

Overall

7.9

Entertainment

7.9

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Charleston to Santo Domingo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Charleston to Santo Domingo?

    For as low as $318, American Airlines can have you in Santo Domingo from Charleston in 7h. Charleston and Santo Domingo are separated by a distance of 1187 mi.

  • What are the cheapest airlines flying from Charleston to Santo Domingo round-trip?

    American Airlines, at $338, was found to be the cheapest airline from Charleston to Santo Domingo. An alternate airline flying to your destination would be Delta. You may be able to fly from Charleston to Santo Domingo for 35% less than the average price by searching for these airlines.

  • Can I find deals for flights from Charleston to Santo Domingo that include hotel bookings?

    Yes. In addition to deals on Charleston to Santo Domingo flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Charleston to Santo Domingo?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Charleston to Santo Domingo.

  • Can I find deals for business class flights from Charleston to Santo Domingo?

    Yes. Cheapflights offers flight deals from Charleston to Santo Domingo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Charleston to Santo Domingo?

    Currently, January is the cheapest month in which you can book a flight from Charleston to Santo Domingo (average of $340). Flying from Charleston to Santo Domingo in June is currently the most expensive (average of $528). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Santo Domingo?

Book flights to Santo Domingo if you plan to visit one of these locations
Juan Dolio

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Top 2 airlines flying from Charleston to Santo Domingo

Discover the top 2 airlines that operate flights from Charleston to Santo Domingo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 12, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$338Average$483FlexibilityNo cancel feeOn-time71%
DeltaCheapest$420Average$704FlexibilityNo cancel feeOn-timeN/A

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