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Santo Domingo

$145+ Cheap flights from Charleston (CHS) to Santo Domingo (SDQ)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/25. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — SDQ
Aug 3 — Aug 101
Sun 8/3
Sun 8/10
1 adult, Economy
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Cheap flight deals from Charleston to Santo Domingo

Discover tips and strategies to find the most affordable flight options for your journey from Charleston (CHS) to Santo Domingo (SDQ). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated July 29, 2025.

Round-trip from

$327
(FlightHub)

One-way from

$145
(SmartFares)

Popular in

December

Cheapest in

September

Average price

$562
From Charleston to Santo Domingo Las Americas
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One-way flight from Charleston to Santo Domingo Las Americas
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Highest demand for flights based on searches. 12% potential increase in price ($82 potential increase over avg. RT price).
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Cheapest flight prices on average. 4% potential price decrease ($26 potential savings vs. average RT price).
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Average for round-trip flights in July 2025
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Find flight deals from Charleston to Santo Domingo

Cheapest flights from Charleston to Santo Domingo
Explore the most affordable flight options available from Charleston to Santo Domingo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 29, 2025.

This FlightHub deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/18:17 pmCHS - SDQ
1 stop19h 43mSpirit Airlines
Wed 9/35:05 pmSDQ - CHS
1 stop18h 00mSpirit Airlines
Deal found 7/28$327
This Kiwi.com deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/158:44 pmCHS - SDQ
1 stop19h 46mMultiple Airlines
Sat 10/253:47 pmSDQ - CHS
1 stop17h 38mMultiple Airlines
Deal found 7/26$365
This Priceline deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/19:40 amCHS - SDQ
1 stop27h 44mJetBlue
Wed 10/82:34 pmSDQ - CHS
1 stop18h 20mJetBlue
Deal found 7/28$402
This Delta deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/38:00 amCHS - SDQ
1 stop5h 22mDelta
Fri 9/56:00 amSDQ - CHS
1 stop10h 58mDelta
Deal found 7/28$441
This American Airlines deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/2810:56 amCHS - SDQ
1 stop9h 34mAmerican Airlines
Mon 9/12:35 pmSDQ - CHS
1 stop9h 24mAmerican Airlines
Deal found 7/29$491
This Copa Airlines deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/227:45 pmCHS - SDQ
2 stops16h 27mCopa Airlines
Tue 12/302:14 pmSDQ - CHS
2 stops21h 10mCopa Airlines
Deal found 7/28$1,384

Cheapflights Fare Finder

 
Customize your flight search to find flights from Charleston to Santo Domingo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 29, 2025.
Use the filters below to find and compare flights from Charleston to Santo Domingo that are best for you.

Fly from

Charleston

Fly to

Santo Domingo

Route

Depart

Return

Price

CharlestonSanto Domingo

CHS - SDQ

CHSSDQ

Charleston

Mon 9/1

8:17 pm-4:00 pm

1 stop19h 43m

Santo Domingo Las Americas

Wed 9/3

5:05 pm-11:05 am

1 stop18h 00m

$327

CharlestonSanto Domingo

CHS - SDQ

CHSSDQ

Charleston

Wed 10/15

8:44 pm-4:30 pm

1 stop19h 46m

Santo Domingo Las Americas

Sat 10/25

3:47 pm-9:25 am

1 stop17h 38m

$365

CharlestonSanto Domingo

CHS - SDQ

CHSSDQ

Charleston

Wed 10/1

9:40 am-1:24 pm

1 stop27h 44m

Santo Domingo Las Americas

Wed 10/8

2:34 pm-8:54 am

1 stop18h 20m

$402

CharlestonSanto Domingo

CHS - SDQ

CHSSDQ

Charleston

Wed 9/3

8:00 am-1:22 pm

1 stop5h 22m

Santo Domingo Las Americas

Fri 9/5

6:00 am-4:58 pm

1 stop10h 58m

$441

CharlestonSanto Domingo

CHS - SDQ

CHSSDQ

Charleston

Thu 8/28

10:56 am-8:30 pm

1 stop9h 34m

Santo Domingo Las Americas

Mon 9/1

2:35 pm-11:59 pm

1 stop9h 24m

$491

CharlestonSanto Domingo

CHS - SDQ

CHSSDQ

Charleston

Mon 12/22

7:45 pm-1:12 pm

2 stops16h 27m

Santo Domingo Las Americas

Tue 12/30

2:14 pm-10:24 am

2 stops21h 10m

$1,384

CharlestonSanto Domingo

CHS - SDQ

CHSSDQ

Charleston

Thu 9/25

12:10 pm-4:00 pm

1 stop27h 50m

$145

CharlestonSanto Domingo

CHS - SDQ

CHSSDQ

Charleston

Mon 8/11

4:30 pm-3:47 pm

2 stops23h 17m

$188

CharlestonSanto Domingo

CHS - SDQ

CHSSDQ

Charleston

Tue 8/12

6:20 am-1:22 pm

1 stop7h 02m

$219

CharlestonSanto Domingo

CHS - SDQ

CHSSDQ

Charleston

Thu 8/28

10:18 am-2:10 pm

3 stops27h 52m

$1,704

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/29

Best time to book a flight from Charleston to Santo Domingo

Have a flexible travel schedule? Discover the best time to fly to Santo Domingo from Charleston with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Charleston to Santo Domingo

What is the cheapest month to book a flight from Charleston to Santo Domingo?

Currently, January is the cheapest month in which you can book a flight from Charleston to Santo Domingo (average of $362). Flying from Charleston to Santo Domingo in December is currently the most expensive (average of $583). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from CHS to SDQ?

Find hourly flight availability from Charleston to Santo Domingo. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated July 29, 2025.

One of the essential ways to save on airfare from Charleston to Santo Domingo is to remain as flexible as possible. Flights that are in the afternoon tend to be the most expensive. A flight at noon could potentially save you up to 60% on airfare.

Reviews of airlines servicing Santo Domingo

Get insights into the airlines that provide service to Santo Domingo. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santo Domingo. Reviews last updated July 29, 2025.
See what other customers who have flown with Delta, Copa Airlines, and United Airlines from Charleston to Santo Domingo have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,979 reviews

Food

7.3

Comfort

7.9

Overall

8.0

Crew

8.5

Boarding

8.2

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,979 reviews
Delta
8.0
Very good
7,979 reviews

Food

7.3

Comfort

7.9

Overall

8.0

Crew

8.5

Boarding

8.2

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Copa Airlines
7.5
Good
1,493 reviews
Delta
8.0
Very good
7,979 reviews

Food

7.3

Comfort

7.9

Overall

8.0

Crew

8.5

Boarding

8.2

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
United Airlines
7.4
Good
8,896 reviews
Delta
8.0
Very good
7,979 reviews

Food

7.3

Comfort

7.9

Overall

8.0

Crew

8.5

Boarding

8.2

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
JetBlue
7.3
Good
2,913 reviews
Delta
8.0
Very good
7,979 reviews

Food

7.3

Comfort

7.9

Overall

8.0

Crew

8.5

Boarding

8.2

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,979 reviews

Food

7.3

Comfort

7.9

Overall

8.0

Crew

8.5

Boarding

8.2

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from Charleston to Santo Domingo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines flying from Charleston to Santo Domingo round-trip?

    Spirit Airlines, at $327, was found to be the cheapest airline from Charleston to Santo Domingo.Alternate airlines to your destination round-trip include JetBlue and Delta. You may be able to fly from Charleston to Santo Domingo for 44% less than the average price by searching for these airlines.

  • What are the cheapest airlines to fly from Charleston to Santo Domingo one-way?

    To fly one-way, consider booking your trip with Spirit Airlines, which is currently one of the cheapest options available, starting at $145. Delta flights start at $219 while deals on United Airlines start at $1,704 one-way.

  • Can I find deals for flights from Charleston to Santo Domingo that include hotel bookings?

    Yes. In addition to deals on Charleston to Santo Domingo flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Charleston to Santo Domingo?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Charleston to Santo Domingo.

  • Can I find deals for business class flights from Charleston to Santo Domingo?

    Yes. Cheapflights offers flight deals from Charleston to Santo Domingo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Charleston to Santo Domingo?

    Currently, January is the cheapest month in which you can book a flight from Charleston to Santo Domingo (average of $362). Flying from Charleston to Santo Domingo in December is currently the most expensive (average of $583). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Santo Domingo?

Book flights to Santo Domingo if you plan to visit one of these locations
Juan Dolio

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Alternative routes for Charleston to Santo Domingo

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Top 2 airlines flying from Charleston to Santo Domingo

Discover the top 2 airlines that operate flights from Charleston to Santo Domingo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 29, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$320Average$574FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$410Average$577FlexibilityNo cancel feeOn-time71%

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