HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Santo Domingo

$121+ Cheap flights from Charleston (CHS) to Santo Domingo (SDQ)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/31. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — SDQ
feb. 27 — mar. 61
vie. 2/27
vie. 3/6
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Charleston to Santo Domingo with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Charleston to Santo Domingo

Cheapest flights from Charleston to Santo Domingo
Explore the most affordable flight options available from Charleston to Santo Domingo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on enero 28, 2026.

This Cheapflightsfares deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 4/148:07 am
CHS
-
SDQ
1 stop5h 18m
Spirit Airlines
mié. 6/33:37 pm
SDQ
-
CHS
1 stop7h 04m
Spirit Airlines
Deal found 1/28$267
This Mytrip deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 3/168:07 am
CHS
-
SDQ
1 stop5h 18m
Spirit Airlines
lun. 3/232:30 pm
SDQ
-
CHS
1 stop8h 03m
Spirit Airlines
Deal found 1/27$269
This Cheapflightsfares deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 3/318:07 am
CHS
-
SDQ
1 stop5h 18m
Spirit Airlines
jue. 4/92:30 pm
SDQ
-
CHS
1 stop8h 03m
Spirit Airlines
Deal found 1/27$282
This Kiwi.com deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 3/198:07 am
CHS
-
SDQ
1 stop17h 31m
Spirit Airlines
vie. 3/272:59 am
SDQ
-
CHS
1 stop19h 34m
Spirit Airlines
Deal found 1/26$313
This American Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 4/226:00 am
CHS
-
SDQ
1 stop7h 18m
American Airlines
sáb. 4/256:00 am
SDQ
-
CHS
1 stop13h 37m
American Airlines
Deal found 1/27$323
This American Airlines deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 1/306:10 am
CHS
-
SDQ
2 stops15h 29m
American Airlines
mar. 2/36:00 am
SDQ
-
CHS
2 stops14h 02m
American Airlines
Deal found 1/26$331
This JetBlue deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 3/512:36 pm
CHS
-
SDQ
1 stop12h 22m
JetBlue
dom. 3/89:36 pm
SDQ
-
CHS
1 stop13h 22m
JetBlue
Deal found 1/27$343
This Kiwi.com deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 2/286:35 pm
CHS
-
SDQ
1 stop18h 45m
Spirit Airlines
sáb. 3/73:32 pm
SDQ
-
CHS
1 stop26h 08m
Spirit Airlines
Deal found 1/28$353
This Kiwi.com deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 3/16:35 pm
CHS
-
SDQ
1 stop18h 45m
Spirit Airlines
mar. 3/102:32 pm
SDQ
-
CHS
2 stops25h 33m
Spirit Airlines
Deal found 1/28$362
This Kiwi.com deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 3/16:35 pm
CHS
-
SDQ
1 stop18h 45m
Spirit Airlines
lun. 3/92:32 pm
SDQ
-
CHS
2 stops25h 33m
Spirit Airlines
Deal found 1/28$363

Find flight deals from Charleston to Santo Domingo

Discover tips and strategies to find the most affordable flight options for your journey from Charleston (CHS) to Santo Domingo (SDQ). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated enero 28, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$267
(Cheapflightsfares)

One-way from

$121
(Cheapflightsfares)

Popular in

April

Cheapest in

November

Average price

$400
Provider with most accurate pricing for Charleston-Santo Domingo Las Americas flight deals.
Search Deals
Provider most trusted by Cheapflights users for Charleston-Santo Domingo Las Americas flights.
Search Deals
From Charleston to Santo Domingo Las Americas
Search Deals
One-way flight from Charleston to Santo Domingo Las Americas
Search Deals
Highest demand for flights based on searches. 15% potential increase in price ($92 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($11 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in January 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Charleston to Santo Domingo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated enero 28, 2026.
Use the filters below to find and compare flights from Charleston to Santo Domingo that are best for you.

Fly from

Charleston

Fly to

Santo Domingo

Route

Depart

Return

Price

CharlestonSanto Domingo

CHS - SDQ

CHSSDQ

Charleston

mar. 4/14

8:07 am-1:25 pm

1 stop5h 18m

Santo Domingo Las Americas

mié. 6/3

3:37 pm-10:41 pm

1 stop7h 04m

$267

CharlestonSanto Domingo

CHS - SDQ

CHSSDQ

Charleston

lun. 3/16

8:07 am-1:25 pm

1 stop5h 18m

Santo Domingo Las Americas

lun. 3/23

2:30 pm-10:33 pm

1 stop8h 03m

$269

CharlestonSanto Domingo

CHS - SDQ

CHSSDQ

Charleston

mar. 3/31

8:07 am-1:25 pm

1 stop5h 18m

Santo Domingo Las Americas

jue. 4/9

2:30 pm-10:33 pm

1 stop8h 03m

$282

CharlestonSanto Domingo

CHS - SDQ

CHSSDQ

Charleston

mié. 4/22

6:00 am-1:18 pm

1 stop7h 18m

Santo Domingo Las Americas

sáb. 4/25

6:00 am-7:37 pm

1 stop13h 37m

$323

CharlestonSanto Domingo

CHS - SDQ

CHSSDQ

Charleston

jue. 3/5

12:36 pm-1:58 am

1 stop12h 22m

Santo Domingo Las Americas

dom. 3/8

9:36 pm-10:58 am

1 stop13h 22m

$343

CharlestonSanto Domingo

CHS - SDQ

CHSSDQ

Charleston

sáb. 2/28

6:35 pm-2:20 pm

1 stop18h 45m

Santo Domingo Las Americas

sáb. 3/7

3:32 pm-4:40 pm

1 stop26h 08m

$353

CharlestonSanto Domingo

CHS - SDQ

CHSSDQ

Charleston

dom. 3/1

6:35 pm-2:20 pm

1 stop18h 45m

Santo Domingo Las Americas

mar. 3/10

2:32 pm-4:05 pm

2 stops25h 33m

$362

CharlestonSanto Domingo

CHS - SDQ

CHSSDQ

Charleston

jue. 3/5

12:36 pm-1:58 am

1 stop12h 22m

Santo Domingo Las Americas

vie. 3/6

10:35 pm-10:57 am

1 stop13h 22m

$363

CharlestonSanto Domingo

CHS - SDQ

CHSSDQ

Charleston

dom. 3/1

6:35 pm-2:20 pm

1 stop18h 45m

Santo Domingo Las Americas

mar. 3/10

5:30 am-4:05 pm

1 stop10h 35m

$367

CharlestonSanto Domingo

CHS - SDQ

CHSSDQ

Charleston

mar. 3/31

8:07 am-1:25 pm

1 stop5h 18m

$121

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/27

Showing 1-10 of 17 results
1
2

Compare providers for flights from Charleston to Santo Domingo

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Charleston to Santo Domingo in January.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars
OvagoPrice Accuracy2 starsTrust Score*3 stars
AranGrantPrice Accuracy2 starsTrust Score*2 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Charleston-Santo Domingo flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Charleston-Santo Domingo flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Charleston-Santo Domingo flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Charleston-Santo Domingo flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Charleston-Santo Domingo flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Charleston to Santo Domingo

Have a flexible travel schedule? Discover the best time to fly to Santo Domingo from Charleston with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Charleston to Santo Domingo

What is the cheapest month to book a flight from Charleston to Santo Domingo?

Currently, January is the cheapest month in which you can book a flight from Charleston to Santo Domingo (average of $324). Flying from Charleston to Santo Domingo in June is currently the most expensive (average of $528). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Charleston to Santo Domingo?

Reviews of airlines servicing Santo Domingo

Get insights into the airlines that provide service to Santo Domingo. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santo Domingo. Reviews last updated enero 28, 2026.
See what other customers who have flown with Delta and American Airlines from Charleston to Santo Domingo have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,123 reviews

Overall

7.9

Food

7.2

Comfort

7.9

Crew

8.5

Boarding

8.1

Entertainment

7.8

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,123 reviews
Delta
7.9
Good
8,123 reviews

Overall

7.9

Food

7.2

Comfort

7.9

Crew

8.5

Boarding

8.1

Entertainment

7.8

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,201 reviews
Delta
7.9
Good
8,123 reviews

Overall

7.9

Food

7.2

Comfort

7.9

Crew

8.5

Boarding

8.1

Entertainment

7.8

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Charleston to Santo Domingo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Charleston to Santo Domingo?

    For as low as $267, Spirit Airlines can have you in Santo Domingo from Charleston in 5h 18m. Charleston and Santo Domingo are separated by a distance of 1187 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines flying from Charleston to Santo Domingo round-trip?

    Delta, at $321, was found to be the cheapest airline from Charleston to Santo Domingo. An alternate airline flying to your destination would be American Airlines. You may be able to fly from Charleston to Santo Domingo for 37% less than the average price by searching for these airlines.

  • Can I find deals for flights from Charleston to Santo Domingo that include hotel bookings?

    Yes. In addition to deals on Charleston to Santo Domingo flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Charleston to Santo Domingo?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Charleston to Santo Domingo.

  • Can I find deals for business class flights from Charleston to Santo Domingo?

    Yes. Cheapflights offers flight deals from Charleston to Santo Domingo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Charleston to Santo Domingo?

    Currently, January is the cheapest month in which you can book a flight from Charleston to Santo Domingo (average of $324). Flying from Charleston to Santo Domingo in June is currently the most expensive (average of $528). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Santo Domingo?

Book flights to Santo Domingo if you plan to visit one of these locations
Juan Dolio

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Charleston to Santo Domingo

See prices for flight routes from nearby airports that may be better suited for you.
Charlotte to Punta Cana flights
Charleston to Punta Cana flights
Charlotte to Santo Domingo flights
Charlotte to Puerto Plata flights
Charlotte to Santiago de los Caballeros flights
Myrtle Beach to Punta Cana flights
Greenville to Punta Cana flights
Savannah to Punta Cana flights
Columbia to Punta Cana flights
Charleston to Puerto Plata flights
Greenville to Santo Domingo flights
Savannah to Santo Domingo flights
Charleston to Santiago de los Caballeros flights
Savannah to Puerto Plata flights
Augusta to Punta Cana flights
Myrtle Beach to Santo Domingo flights
Columbia to Santiago de los Caballeros flights
Greenville to Santiago de los Caballeros flights
Charlotte to Nagua flights
Columbia to Puerto Plata flights
Myrtle Beach to Puerto Plata flights
Augusta to Puerto Plata flights
Hilton Head Island to Punta Cana flights
Augusta to Santiago de los Caballeros flights

Top 2 airlines flying from Charleston to Santo Domingo

Discover the top 2 airlines that operate flights from Charleston to Santo Domingo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated enero 28, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$321Average$704FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$333Average$492FlexibilityNo cancel feeOn-time71%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.
Site
Cookie settings©2026 Cheapflights