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Santo Domingo

$313+ Cheap flights from Charleston (CHS) to Santo Domingo (SDQ)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/7. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — SDQ
Oct 11 — Oct 181
Sat 10/11
Sat 10/18
1 adult, Economy
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Cheap flight deals from Charleston to Santo Domingo

Discover tips and strategies to find the most affordable flight options for your journey from Charleston (CHS) to Santo Domingo (SDQ). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 11, 2025.

Round-trip from

$313
(Kiwi.com)

Popular in

December

Cheapest in

September

Average price

$414
From Charleston to Santo Domingo Las Americas
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Highest demand for flights based on searches. 8% potential increase in price ($55 potential increase over avg. RT price).
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Cheapest flight prices on average. 4% potential price decrease ($27 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from Charleston to Santo Domingo

Cheapest flights from Charleston to Santo Domingo
Explore the most affordable flight options available from Charleston to Santo Domingo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 11, 2025.

This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/75:40 pmCHS - SDQ
1 stop23h 10mSpirit Airlines
Wed 11/126:55 pmSDQ - CHS
1 stop16h 50mSpirit Airlines
Deal found 9/10$313
This American Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/197:44 pmCHS - SDQ
1 stop13h 41mAmerican Airlines
Sat 10/254:20 pmSDQ - CHS
1 stop7h 39mAmerican Airlines
Deal found 9/11$315
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/136:00 amCHS - SDQ
1 stop12h 08mDelta
Sun 11/166:45 amSDQ - CHS
1 stop11h 20mDelta
Deal found 9/10$317
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/147:57 pmCHS - SDQ
1 stop15h 22mAmerican Airlines
Mon 11/244:45 pmSDQ - CHS
1 stop8h 18mAmerican Airlines
Deal found 9/10$323
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/2510:10 amCHS - SDQ
1 stop5h 10mAmerican Airlines
Tue 9/3012:15 pmSDQ - CHS
1 stop11h 43mAmerican Airlines
Deal found 9/10$327
This American Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/137:57 pmCHS - SDQ
1 stop18h 48mAmerican Airlines
Sun 11/166:24 pmSDQ - CHS
2 stops16h 22mAmerican Airlines
Deal found 9/11$334
This Mytrip deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/1010:11 amCHS - SDQ
1 stop5h 56mSpirit Airlines
Mon 10/135:12 pmSDQ - CHS
2 stops25h 29mSpirit Airlines
Deal found 9/11$371
This Expedia deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/145:20 pmCHS - SDQ
1 stop16h 12mJetBlue
Sun 11/234:09 amSDQ - CHS
1 stop6h 32mJetBlue
Deal found 9/10$379
This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/75:40 pmCHS - SDQ
1 stop23h 10mMultiple Airlines
Wed 11/128:55 amSDQ - CHS
2 stops26h 50mMultiple Airlines
Deal found 9/10$382

Cheapflights Fare Finder

 
Customize your flight search to find flights from Charleston to Santo Domingo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
Use the filters below to find and compare flights from Charleston to Santo Domingo that are best for you.

Fly from

Charleston

Fly to

Santo Domingo

Route

Depart

Return

Price

CharlestonSanto Domingo

CHS - SDQ

CHSSDQ

Charleston

Fri 11/7

5:40 pm-5:50 pm

1 stop23h 10m

Santo Domingo Las Americas

Wed 11/12

6:55 pm-10:45 am

1 stop16h 50m

$313

CharlestonSanto Domingo

CHS - SDQ

CHSSDQ

Charleston

Thu 11/13

6:00 am-7:08 pm

1 stop12h 08m

Santo Domingo Las Americas

Sun 11/16

6:45 am-5:05 pm

1 stop11h 20m

$317

CharlestonSanto Domingo

CHS - SDQ

CHSSDQ

Charleston

Fri 11/14

7:57 pm-12:19 pm

1 stop15h 22m

Santo Domingo Las Americas

Mon 11/24

4:45 pm-12:03 am

1 stop8h 18m

$323

CharlestonSanto Domingo

CHS - SDQ

CHSSDQ

Charleston

Thu 9/25

10:10 am-3:20 pm

1 stop5h 10m

Santo Domingo Las Americas

Tue 9/30

12:15 pm-11:58 pm

1 stop11h 43m

$327

CharlestonSanto Domingo

CHS - SDQ

CHSSDQ

Charleston

Thu 11/13

7:57 pm-3:45 pm

1 stop18h 48m

Santo Domingo Las Americas

Sun 11/16

6:24 pm-9:46 am

2 stops16h 22m

$334

CharlestonSanto Domingo

CHS - SDQ

CHSSDQ

Charleston

Fri 10/10

10:11 am-4:07 pm

1 stop5h 56m

Santo Domingo Las Americas

Mon 10/13

5:12 pm-6:41 pm

2 stops25h 29m

$371

CharlestonSanto Domingo

CHS - SDQ

CHSSDQ

Charleston

Fri 11/7

5:40 pm-5:50 pm

1 stop23h 10m

Santo Domingo Las Americas

Wed 11/12

8:55 am-10:45 am

2 stops26h 50m

$382

CharlestonSanto Domingo

CHS - SDQ

CHSSDQ

Charleston

Fri 11/7

2:15 pm-10:23 pm

1 stop7h 08m

Santo Domingo Las Americas

Tue 11/11

4:10 am-1:19 pm

1 stop10h 09m

$385

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/10

Best time to book a flight from Charleston to Santo Domingo

Have a flexible travel schedule? Discover the best time to fly to Santo Domingo from Charleston with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Charleston to Santo Domingo

What is the cheapest month to book a flight from Charleston to Santo Domingo?

Currently, January is the cheapest month in which you can book a flight from Charleston to Santo Domingo (average of $362). Flying from Charleston to Santo Domingo in December is currently the most expensive (average of $583). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from CHS to SDQ?

Find hourly flight availability from Charleston to Santo Domingo. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 11, 2025.

One of the essential ways to save on airfare from Charleston to Santo Domingo is to remain as flexible as possible. Flights that are in the afternoon tend to be the most expensive. A flight at noon could potentially save you up to 60% on airfare.

How much does it cost to fly round-trip from Charleston to Santo Domingo?

Reviews of airlines servicing Santo Domingo

Get insights into the airlines that provide service to Santo Domingo. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santo Domingo. Reviews last updated September 11, 2025.
See what other customers who have flown with Delta and American Airlines from Charleston to Santo Domingo have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,960 reviews

Crew

8.5

Boarding

8.2

Entertainment

7.9

Overall

8.0

Food

7.3

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,960 reviews
Delta
8.0
Very good
7,960 reviews

Crew

8.5

Boarding

8.2

Entertainment

7.9

Overall

8.0

Food

7.3

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,960 reviews

Crew

8.5

Boarding

8.2

Entertainment

7.9

Overall

8.0

Food

7.3

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from Charleston to Santo Domingo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Charleston to Santo Domingo?

    For as low as $317, Spirit Airlines can have you in Santo Domingo from Charleston in 12h 08m. Charleston and Santo Domingo are separated by a distance of 1187 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines flying from Charleston to Santo Domingo round-trip?

    American Airlines, at $420, was found to be the cheapest airline from Charleston to Santo Domingo. An alternate airline flying to your destination would be Delta. You may be able to fly from Charleston to Santo Domingo for 27% less than the average price by searching for these airlines.

  • Can I find deals for flights from Charleston to Santo Domingo that include hotel bookings?

    Yes. In addition to deals on Charleston to Santo Domingo flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Charleston to Santo Domingo?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Charleston to Santo Domingo.

  • Can I find deals for business class flights from Charleston to Santo Domingo?

    Yes. Cheapflights offers flight deals from Charleston to Santo Domingo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Charleston to Santo Domingo?

    Currently, January is the cheapest month in which you can book a flight from Charleston to Santo Domingo (average of $362). Flying from Charleston to Santo Domingo in December is currently the most expensive (average of $583). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Santo Domingo?

Book flights to Santo Domingo if you plan to visit one of these locations
Juan Dolio

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Alternative routes for Charleston to Santo Domingo

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Top 2 airlines flying from Charleston to Santo Domingo

Discover the top 2 airlines that operate flights from Charleston to Santo Domingo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$420Average$588FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$420Average$577FlexibilityNo cancel feeOn-time71%

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