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Santiago de los Caballeros

$471+ Cheap flights from St. Louis (STL) to Santiago de los Caballeros (STI)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/15. Fares are subject to change and may not be available on all flights or dates of travel.
STL — STI
Dec 13 — Dec 201
Sat 12/13
Sat 12/20
1 adult, Economy
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Cheap flight deals from St. Louis to Santiago de los Caballeros

Discover tips and strategies to find the most affordable flight options for your journey from St. Louis (STL) to Santiago de los Caballeros (STI). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated November 13, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$471
(Kiwi.com)

Popular in

February

Cheapest in

October

Average price

$724
Provider with most accurate pricing for Lambert-St Louis-Santiago de los Caballeros flight deals.
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Provider most trusted by Cheapflights users for Lambert-St Louis-Santiago de los Caballeros flights.
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From Lambert-St Louis to Santiago de los Caballeros
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Highest demand for flights based on searches. 15% potential increase in price ($131 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($20 potential savings vs. average RT price).
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Average for round-trip flights in November 2025
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Find flight deals from St. Louis to Santiago de los Caballeros

Cheapest flights from St. Louis to Santiago de los Caballeros
Explore the most affordable flight options available from St. Louis to Santiago de los Caballeros. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 13, 2025.

This Kiwi.com deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/1510:47 amSTL - STI
2 stops13h 55mMultiple Airlines
Mon 12/293:43 amSTI - STL
1 stop9h 13mMultiple Airlines
Deal found 11/11$471
This Kiwi.com deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/163:30 pmSTL - STI
2 stops33h 12mMultiple Airlines
Mon 12/293:43 amSTI - STL
1 stop9h 13mMultiple Airlines
Deal found 11/12$592
This Mytrip deal was found by Cheapflights users on 11/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/142:47 pmSTL - STI
1 stop9h 55mSpirit Airlines
Mon 1/53:43 amSTI - STL
1 stop9h 13mSpirit Airlines
Deal found 11/13$666
This Kiwi.com deal was found by Cheapflights users on 11/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/143:30 pmSTL - STI
2 stops33h 12mMultiple Airlines
Mon 1/53:43 amSTI - STL
1 stop9h 13mMultiple Airlines
Deal found 11/13$722
This American Airlines deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/265:05 amSTL - STI
1 stop13h 59mAmerican Airlines
Mon 12/293:24 pmSTI - STL
1 stop9h 11mAmerican Airlines
Deal found 11/12$836
This American Airlines deal was found by Cheapflights users on 11/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/146:00 amSTL - STI
2 stops12h 33mAmerican Airlines
Tue 1/64:33 pmSTI - STL
1 stop18h 35mAmerican Airlines
Deal found 11/13$884
This United Airlines deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/1610:00 amSTL - STI
2 stops11h 51mUnited Airlines
Wed 12/314:00 pmSTI - STL
1 stop9h 57mUnited Airlines
Deal found 11/11$916

Cheapflights Fare Finder

 
Customize your flight search to find flights from St. Louis to Santiago de los Caballeros that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 13, 2025.
Use the filters below to find and compare flights from St. Louis to Santiago de los Caballeros that are best for you.

Fly from

St. Louis

Fly to

Santiago de los Caballeros

Route

Depart

Return

Price

St. LouisSantiago de los Caballeros

STL - STI

STLSTI

Lambert-St Louis

Mon 12/15

10:47 am-2:42 am

2 stops13h 55m

Santiago de los Caballeros

Mon 12/29

3:43 am-10:56 am

1 stop9h 13m

$471

St. LouisSantiago de los Caballeros

STL - STI

STLSTI

Lambert-St Louis

Thu 2/26

6:00 am-12:53 am

2 stops16h 53m

Santiago de los Caballeros

Mon 3/2

10:05 pm-2:49 pm

2 stops18h 44m

$562

St. LouisSantiago de los Caballeros

STL - STI

STLSTI

Lambert-St Louis

Sat 2/21

5:55 pm-1:32 pm

2 stops17h 37m

Santiago de los Caballeros

Sat 2/28

2:34 pm-11:00 am

2 stops22h 26m

$582

St. LouisSantiago de los Caballeros

STL - STI

STLSTI

Lambert-St Louis

Tue 12/16

3:30 pm-2:42 am

2 stops33h 12m

Santiago de los Caballeros

Mon 12/29

3:43 am-10:56 am

1 stop9h 13m

$592

St. LouisSantiago de los Caballeros

STL - STI

STLSTI

Lambert-St Louis

Thu 2/26

6:30 am-11:51 pm

2 stops15h 21m

Santiago de los Caballeros

Mon 3/2

4:00 pm-12:05 am

1 stop10h 05m

$632

St. LouisSantiago de los Caballeros

STL - STI

STLSTI

Lambert-St Louis

Sun 12/14

2:47 pm-2:42 am

1 stop9h 55m

Santiago de los Caballeros

Mon 1/5

3:43 am-10:56 am

1 stop9h 13m

$666

St. LouisSantiago de los Caballeros

STL - STI

STLSTI

Lambert-St Louis

Mon 12/22

6:30 am-2:53 pm

2 stops30h 23m

$989

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/10

Compare providers for flights from St. Louis to Santiago de los Caballeros

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from St. Louis to Santiago de los Caballeros in November.
ProviderPrice AccuracyTrust Score*
FlightHubPrice Accuracy3 starsTrust Score*1 star
eDreamsPrice Accuracy3 starsTrust Score*3 stars
AranGrantPrice Accuracy2 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on St. Louis-Santiago de los Caballeros flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on St. Louis-Santiago de los Caballeros flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from St. Louis-Santiago de los Caballeros flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on St. Louis-Santiago de los Caballeros flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for St. Louis-Santiago de los Caballeros flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from St. Louis to Santiago de los Caballeros

Have a flexible travel schedule? Discover the best time to fly to Santiago de los Caballeros from St. Louis with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from St. Louis to Santiago de los Caballeros

What is the cheapest month to book a flight from St. Louis to Santiago de los Caballeros?

Currently, April is the cheapest month in which you can book a flight from St. Louis to Santiago de los Caballeros (average of $374). Flying from St. Louis to Santiago de los Caballeros in June is currently the most expensive (average of $610). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Santiago de los Caballeros

Get insights into the airlines that provide service to Santiago de los Caballeros. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santiago de los Caballeros. Reviews last updated November 13, 2025.
Get a feel of what it's like to fly with American Airlines from St. Louis to Santiago de los Caballeros by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.2
Good
11,051 reviews

Crew

8.0

Comfort

7.2

Entertainment

6.9

Food

6.4

Overall

7.2

Boarding

7.5

Reviews

1 / 20
8.0
Excellent

Monica,Nov 2025

JAC - DFW

At least there was an option of entertainment on this flight.
American Airlines
7.2
Good
11,051 reviews
American Airlines
7.2
Good
11,051 reviews

Crew

8.0

Comfort

7.2

Entertainment

6.9

Food

6.4

Overall

7.2

Boarding

7.5

Reviews

1 / 20
8.0
Excellent

Monica,Nov 2025

JAC - DFW

At least there was an option of entertainment on this flight.

Related info for your journey

Find useful and relevant information for your journey from St. Louis to Santiago de los Caballeros. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from St. Louis to Santiago de los Caballeros?

    A quick flight from St. Louis to Santiago de los Caballeros can take about 16h 53m. Delta provides one of the quickest options available for as low as $562. Airlines will cover a distance of 1782 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What is the cheapest airline to fly from St. Louis to Santiago de los Caballeros round-trip?

    According to our current data, American Airlines ($604), offers the cheapest pricing from St. Louis to Santiago de los Caballeros. American Airlines is currently priced 14% below the average price you’ll pay for this route.

  • Can I find deals for flights from St. Louis to Santiago de los Caballeros that include hotel bookings?

    Yes. In addition to deals on St. Louis to Santiago de los Caballeros flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from St. Louis to Santiago de los Caballeros?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from St. Louis to Santiago de los Caballeros.

  • Can I find deals for business class flights from St. Louis to Santiago de los Caballeros?

    Yes. Cheapflights offers flight deals from St. Louis to Santiago de los Caballeros by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from St. Louis to Santiago de los Caballeros?

    Currently, April is the cheapest month in which you can book a flight from St. Louis to Santiago de los Caballeros (average of $374). Flying from St. Louis to Santiago de los Caballeros in June is currently the most expensive (average of $610). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top airline flying from St. Louis to Santiago de los Caballeros

Discover the top airline that operate flights from St. Louis to Santiago de los Caballeros. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 13, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$604Average$819FlexibilityNo cancel feeOn-time71%

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