What is the cheapest airline to fly from St. Louis to Santiago de los Caballeros round-trip?

According to our current data, Spirit Airlines ($399), offers the cheapest pricing from St. Louis to Santiago de los Caballeros. Spirit Airlines is currently priced 42% below the average price you’ll pay for this route.

What is the cheapest day to fly from St. Louis to Santiago de los Caballeros?

Travelers seeking maximum savings on their St. Louis to Santiago de los Caballeros flight should consider departing on Tuesday mornings when fares are most often at their lowest. Friday mornings flights should be avoided if possible as fares are typically the most expensive at this time.

What is the cheapest day to fly round-trip from St. Louis to Santiago de los Caballeros?

Departing on a Monday is a good option for securing a great price. You can expect to save up to 52% when planning your travel around this day of the week.

What is the cheapest month to fly from St. Louis to Santiago de los Caballeros?

Our data shows that September tends to be the cheapest month to fly to Santiago de los Caballeros from St. Louis. Users have commonly found prices around $693 for the month, but tickets can be as low as $505. Due to multiple factors, prepare for potentially higher prices in December.

What is the cheapest time of day to fly from STL to STI?

One of the essential ways to save on airfare from St. Louis to Santiago de los Caballeros is to remain as flexible as possible. Flights that are at noon tend to be the most expensive. A flight in the morning could potentially save you up to 23% on airfare.

How can I find direct flights from St. Louis to Santiago de los Caballeros?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from St. Louis to Santiago de los Caballeros.

Can I find deals for business class flights from St. Louis to Santiago de los Caballeros?

Yes. Cheapflights offers flight deals from St. Louis to Santiago de los Caballeros by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$193+ Flights from St. Louis to Santiago de los Caballeros

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Cheap flight deals from St. Louis to Santiago de los Caballeros

Round-trip from	$399 (FlightHub)
One-way from	$193 (SmartFares)
Popular in	December
Cheapest in	September

From Lambert-St Louis to Santiago de los Caballeros

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One-way flight from Lambert-St Louis to Santiago de los Caballeros

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Highest demand for flights based on searches. 12% potential increase in price ($100 potential increase over avg. RT price).

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Cheapest flight prices on average. 2% potential price decrease ($19 potential savings vs. average RT price).

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Find flight deals from St. Louis to Santiago de los Caballeros

Cheapest flights from St. Louis to Santiago de los Caballeros
Explore the most affordable flight options available from St. Louis to Santiago de los Caballeros. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 12, 2025.

Fri 7/42:55 pmSTL - STI

1 stop18h 34mSpirit Airlines

Fri 7/1110:55 amSTI - STL

1 stop28h 44mSpirit Airlines

Deal found 6/10

$399

Best flights from St. Louis to Santiago de los Caballeros
Discover carefully curated flight deals from St. Louis to Santiago de los Caballeros that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 12, 2025.

Fri 7/42:55 pmSTL - STI

1 stop18h 34mSpirit Airlines

Fri 7/1110:55 amSTI - STL

1 stop28h 44mSpirit Airlines

Deal found 6/10

$399

Last-minute flights from St. Louis to Santiago de los Caballeros
Discover last-minute flight deals from St. Louis to Santiago de los Caballeros. Data last updated June 12, 2025 and is based on user searches.

Fri 7/42:55 pmSTL - STI

1 stop18h 34mSpirit Airlines

Fri 7/1110:55 amSTI - STL

1 stop28h 44mSpirit Airlines

Deal found 6/10

$399

One-way flights from St. Louis to Santiago de los Caballeros
Search for one-way flight options from St. Louis to Santiago de los Caballeros. Find affordable one-way fares based on user searches. Data last updated June 12, 2025.

Fri 7/42:55 pmSTL - STI

1 stop18h 34mSpirit Airlines

Deal found 6/10

$193

Sat 6/285:47 pmSTL - STI

2 stops39h 42mMultiple Airlines

Deal found 6/10

$343

Sat 6/285:25 amSTL - STI

1 stop14h 40mAmerican Airlines

Deal found 6/10

$373

Cheapflights Fare Finder

Use the filters below to find and compare flights from St. Louis to Santiago de los Caballeros that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

St. LouisSantiago de los Caballeros

STL - STI

STLSTI

Lambert-St Louis

Fri 7/4

2:55 pm-10:29 am

1 stop18h 34m

Santiago de los Caballeros

Fri 7/11

10:55 am-2:39 pm

1 stop28h 44m

$399

St. LouisSantiago de los Caballeros

STL - STI

STLSTI

Lambert-St Louis

Fri 7/4

2:55 pm-10:29 am

1 stop18h 34m

$193

St. LouisSantiago de los Caballeros

STL - STI

STLSTI

Lambert-St Louis

Sat 6/28

5:47 pm-10:29 am

2 stops39h 42m

$343

St. LouisSantiago de los Caballeros

STL - STI

STLSTI

Lambert-St Louis

Sat 6/28

5:25 am-9:05 pm

1 stop14h 40m

$373

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/10

Best time to book a flight from St. Louis to Santiago de los Caballeros

Have a flexible travel schedule? Discover the best time to fly to Santiago de los Caballeros from St. Louis with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from St. Louis to Santiago de los Caballeros

What is the cheapest month to book a flight from St. Louis to Santiago de los Caballeros?

Currently, May is the cheapest month in which you can book a flight from St. Louis to Santiago de los Caballeros (average of $347). Flying from St. Louis to Santiago de los Caballeros in July is currently the most expensive (average of $630). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Rainfall in Santiago de los Caballeros by month

In terms of precipitation, rainfall in Santiago de los Caballeros ranges from 3.0 - 11.6 inches per month. December is typically the wettest month, when rainfall can reach 11.6 in. July is typically the driest time to visit Santiago de los Caballeros when rainfall is around 3.0 in.

Temperature in Santiago de los Caballeros by month

If weather is an important factor for your trip to Santiago de los Caballeros, use this chart to help with planning. For those seeking warmer temperatures, June is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 73.4 F).

Reviews of airlines servicing Santiago de los Caballeros

American Airlines

7.2

Good

10,000 reviews

Reviews

1 / 20

10.0

Excellent

Leonardo,May 2025

JFK - BGI

Good airline and so far i give them 8 out of 10.

American Airlines

7.2

Good

10,000 reviews

American Airlines

7.2

Good

10,000 reviews

Reviews

1 / 20

10.0

Excellent

Leonardo,May 2025

JFK - BGI

Good airline and so far i give them 8 out of 10.

Spirit Airlines

6.3

Okay

8,052 reviews

American Airlines

7.2

Good

10,000 reviews

Reviews

1 / 20

10.0

Excellent

Leonardo,May 2025

JFK - BGI

Good airline and so far i give them 8 out of 10.

Related info for your journey

What is the cheapest airline to fly from St. Louis to Santiago de los Caballeros round-trip?
According to our current data, Spirit Airlines ($399), offers the cheapest pricing from St. Louis to Santiago de los Caballeros. Spirit Airlines is currently priced 42% below the average price you’ll pay for this route.
Can I find deals for flights from St. Louis to Santiago de los Caballeros that include hotel bookings?
Yes. In addition to deals on St. Louis to Santiago de los Caballeros flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from St. Louis to Santiago de los Caballeros?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from St. Louis to Santiago de los Caballeros.
Can I find deals for business class flights from St. Louis to Santiago de los Caballeros?
Yes. Cheapflights offers flight deals from St. Louis to Santiago de los Caballeros by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from St. Louis to Santiago de los Caballeros?
Currently, May is the cheapest month in which you can book a flight from St. Louis to Santiago de los Caballeros (average of $347). Flying from St. Louis to Santiago de los Caballeros in July is currently the most expensive (average of $630). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Top airline flying from St. Louis to Santiago de los Caballeros

Airline	Cheapest	Average	Flexibility	On-time
American Airlines	Cheapest$699	Average$887	FlexibilityNo cancel fee	On-time71%

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$193+ Cheap flights from St. Louis (STL) to Santiago de los Caballeros (STI)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/4. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from St. Louis to Santiago de los Caballeros with Cheapflights

1. Tell us where you want to go

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3. Compare prices and book

Cheap flight deals from St. Louis to Santiago de los Caballeros

Round-trip from

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Popular in

Cheapest in

Find flight deals from St. Louis to Santiago de los Caballeros

Cheapest flights from St. Louis to Santiago de los CaballerosExplore the most affordable flight options available from St. Louis to Santiago de los Caballeros. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 12, 2025.

Explore the most affordable flight options available from St. Louis to Santiago de los Caballeros. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 12, 2025.

Cheapflights Fare Finder

Use the filters below to find and compare flights from St. Louis to Santiago de los Caballeros that are best for you.

Best time to book a flight from St. Louis to Santiago de los Caballeros

Have a flexible travel schedule? Discover the best time to fly to Santiago de los Caballeros from St. Louis with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from St. Louis to Santiago de los Caballeros

What is the cheapest month to book a flight from St. Louis to Santiago de los Caballeros?

Rainfall in Santiago de los Caballeros by month

Plan your trip to Santiago de los Caballeros by taking into account the average rainfall totals by month.

Temperature in Santiago de los Caballeros by month

Plan your trip to Santiago de los Caballeros by taking into account the average temperature totals by month.

Reviews of airlines servicing Santiago de los Caballeros

Related info for your journey

Find useful and relevant information for your journey from St. Louis to Santiago de los Caballeros. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What is the cheapest airline to fly from St. Louis to Santiago de los Caballeros round-trip?

Can I find deals for flights from St. Louis to Santiago de los Caballeros that include hotel bookings?

How can I find direct flights from St. Louis to Santiago de los Caballeros?

Can I find deals for business class flights from St. Louis to Santiago de los Caballeros?

What is the cheapest month to book a flight from St. Louis to Santiago de los Caballeros?

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for St. Louis to Santiago de los Caballeros

See prices for flight routes from nearby airports that may be better suited for you.

Top airline flying from St. Louis to Santiago de los Caballeros

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Cheapest flights from St. Louis to Santiago de los Caballeros
Explore the most affordable flight options available from St. Louis to Santiago de los Caballeros. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 12, 2025.