How long is the flight from St. Louis to Santiago de los Caballeros?

A quick flight from St. Louis to Santiago de los Caballeros can take about 10h 02m. United Airlines provides one of the quickest options available for as low as $517. Airlines will cover a distance of 1782 mi.

What is the cheapest airline to fly from St. Louis to Santiago de los Caballeros round-trip?

According to our current data, American Airlines ($604), offers the cheapest pricing from St. Louis to Santiago de los Caballeros. American Airlines is currently priced 14% below the average price you’ll pay for this route.

What is the cheapest day to fly from St. Louis to Santiago de los Caballeros?

Travelers seeking maximum savings on their St. Louis to Santiago de los Caballeros flight should consider departing on Tuesday mornings when fares are most often at their lowest. Friday mornings flights should be avoided if possible as fares are typically the most expensive at this time.

In terms of precipitation, rainfall in Santiago de los Caballeros ranges from 3.0 - 11.6 inches per month. December is typically the wettest month, when rainfall can reach 11.6 in. July is typically the driest time to visit Santiago de los Caballeros when rainfall is around 3.0 in.

If weather is an important factor for your trip to Santiago de los Caballeros, use this chart to help with planning. For those seeking warmer temperatures, June is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 73.4 F).

What is the cheapest time of day to fly from STL to STI?

One of the essential ways to save on airfare from St. Louis to Santiago de los Caballeros is to remain as flexible as possible. Flights that are at noon tend to be the most expensive. A flight in the morning could potentially save you up to 23% on airfare.

Most accurate provider : When it comes to deals on St. Louis-Santiago de los Caballeros flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on St. Louis-Santiago de los Caballeros flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from St. Louis-Santiago de los Caballeros flight searches over the past month and is updated monthly.

Most trusted provider : When it comes to deals on St. Louis-Santiago de los Caballeros flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for St. Louis-Santiago de los Caballeros flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

How can I find direct flights from St. Louis to Santiago de los Caballeros?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from St. Louis to Santiago de los Caballeros.

Can I find deals for business class flights from St. Louis to Santiago de los Caballeros?

Yes. Cheapflights offers flight deals from St. Louis to Santiago de los Caballeros by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$479+ Cheap Flights from St. Louis to Santiago de los Caballeros

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1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from St. Louis to Santiago de los Caballeros

Most accurate provider	FlightHub 3 stars
Most trusted provider	FlightHub 3 stars
Round-trip from	$479 (Kiwi.com)
Popular in	February
Cheapest in	April
Average price	$582

Provider with most accurate pricing for Lambert-St Louis-Santiago de los Caballeros flight deals.

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Provider most trusted by Cheapflights users for Lambert-St Louis-Santiago de los Caballeros flights.

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From Lambert-St Louis to Santiago de los Caballeros

Search Deals

Highest demand for flights based on searches. 14% potential increase in price ($117 potential increase over avg. RT price).

Search Deals

Cheapest flight prices on average. 2% potential price decrease ($21 potential savings vs. average RT price).

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Average for round-trip flights in September 2025

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Find flight deals from St. Louis to Santiago de los Caballeros

Cheapest flights from St. Louis to Santiago de los Caballeros
Explore the most affordable flight options available from St. Louis to Santiago de los Caballeros. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 25, 2025.

Wed 11/197:24 pmSTL - STI

2 stops19h 42mMultiple Airlines

Wed 12/36:18 pmSTI - STL

1 stop18h 43mMultiple Airlines

Deal found 9/24

$479

Wed 11/1911:49 amSTL - STI

1 stop10h 02mUnited Airlines

Wed 12/34:00 pmSTI - STL

1 stop9h 42mUnited Airlines

Deal found 9/24

$517

Sun 9/289:20 amSTL - STI

2 stops15h 26mUnited Airlines

Tue 9/306:00 amSTI - STL

2 stops10h 44mUnited Airlines

Deal found 9/24

$864

Best flights from St. Louis to Santiago de los Caballeros
Discover carefully curated flight deals from St. Louis to Santiago de los Caballeros that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 25, 2025.

Wed 11/197:24 pmSTL - STI

2 stops19h 42mMultiple Airlines

Wed 12/36:18 pmSTI - STL

1 stop18h 43mMultiple Airlines

Deal found 9/24

$479

Wed 11/1911:49 amSTL - STI

1 stop10h 02mUnited Airlines

Wed 12/34:00 pmSTI - STL

1 stop9h 42mUnited Airlines

Deal found 9/24

$517

Sun 9/285:28 pmSTL - STI

2 stops20h 44mUnited Airlines

Tue 9/304:23 pmSTI - STL

1 stop8h 34mUnited Airlines

Deal found 9/24

$864

Last-minute flights from St. Louis to Santiago de los Caballeros
Discover last-minute flight deals from St. Louis to Santiago de los Caballeros. Data last updated September 25, 2025 and is based on user searches.

Sun 9/285:28 pmSTL - STI

2 stops20h 44mUnited Airlines

Tue 9/304:23 pmSTI - STL

1 stop8h 34mUnited Airlines

Deal found 9/24

$864

Cheapflights Fare Finder

Use the filters below to find and compare flights from St. Louis to Santiago de los Caballeros that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

St. LouisSantiago de los Caballeros

STL - STI

STLSTI

Lambert-St Louis

Wed 11/19

7:24 pm-5:06 pm

2 stops19h 42m

Santiago de los Caballeros

Wed 12/3

6:18 pm-11:01 am

1 stop18h 43m

$479

St. LouisSantiago de los Caballeros

STL - STI

STLSTI

Lambert-St Louis

Wed 11/19

11:49 am-11:51 pm

1 stop10h 02m

Santiago de los Caballeros

Wed 12/3

4:00 pm-11:42 pm

1 stop9h 42m

$517

St. LouisSantiago de los Caballeros

STL - STI

STLSTI

Lambert-St Louis

Sun 9/28

5:28 pm-3:12 pm

2 stops20h 44m

Santiago de los Caballeros

Tue 9/30

4:23 pm-11:57 pm

1 stop8h 34m

$864

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/24

Compare providers for flights from St. Louis to Santiago de los Caballeros

Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from St. Louis to Santiago de los Caballeros in September.

Provider	Price Accuracy	Trust Score*
FlightHub	Price Accuracy3 stars	Trust Score*3 stars
eDreams	Price Accuracy3 stars	Trust Score*3 stars
AranGrant	Price Accuracy3 stars	Trust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

Most accurate provider: When it comes to deals on St. Louis-Santiago de los Caballeros flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on St. Louis-Santiago de los Caballeros flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from St. Louis-Santiago de los Caballeros flight searches over the past month and is updated monthly.
Most trusted provider: When it comes to deals on St. Louis-Santiago de los Caballeros flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for St. Louis-Santiago de los Caballeros flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from St. Louis to Santiago de los Caballeros

Have a flexible travel schedule? Discover the best time to fly to Santiago de los Caballeros from St. Louis with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from St. Louis to Santiago de los Caballeros

What is the cheapest month to book a flight from St. Louis to Santiago de los Caballeros?

Currently, May is the cheapest month in which you can book a flight from St. Louis to Santiago de los Caballeros (average of $347). Flying from St. Louis to Santiago de los Caballeros in July is currently the most expensive (average of $600). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Santiago de los Caballeros

Get a feel of what it's like to fly with American Airlines from St. Louis to Santiago de los Caballeros by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.

American Airlines

7.2

Good

10,000 reviews

Reviews

1 / 20

2.0

Mediocre

Jeremy,Sep 2025

SAN - PHL

Terrible. Bad customer service and unacceptable delay on the tarmac

American Airlines

7.2

Good

10,000 reviews

American Airlines

7.2

Good

10,000 reviews

Reviews

1 / 20

2.0

Mediocre

Jeremy,Sep 2025

SAN - PHL

Terrible. Bad customer service and unacceptable delay on the tarmac

Related info for your journey

How long is the flight from St. Louis to Santiago de los Caballeros?
A quick flight from St. Louis to Santiago de los Caballeros can take about 10h 02m. United Airlines provides one of the quickest options available for as low as $517. Airlines will cover a distance of 1782 mi.
What is the cheapest airline to fly from St. Louis to Santiago de los Caballeros round-trip?
According to our current data, American Airlines ($604), offers the cheapest pricing from St. Louis to Santiago de los Caballeros. American Airlines is currently priced 14% below the average price you’ll pay for this route.
Can I find deals for flights from St. Louis to Santiago de los Caballeros that include hotel bookings?
Yes. In addition to deals on St. Louis to Santiago de los Caballeros flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from St. Louis to Santiago de los Caballeros?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from St. Louis to Santiago de los Caballeros.
Can I find deals for business class flights from St. Louis to Santiago de los Caballeros?
Yes. Cheapflights offers flight deals from St. Louis to Santiago de los Caballeros by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from St. Louis to Santiago de los Caballeros?
Currently, May is the cheapest month in which you can book a flight from St. Louis to Santiago de los Caballeros (average of $347). Flying from St. Louis to Santiago de los Caballeros in July is currently the most expensive (average of $600). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Top airline flying from St. Louis to Santiago de los Caballeros

Airline	Cheapest	Average	Flexibility	On-time
American Airlines	Cheapest$604	Average$864	FlexibilityNo cancel fee	On-time71%

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$479+ Cheap flights from St. Louis (STL) to Santiago de los Caballeros (STI)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/19. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from St. Louis to Santiago de los Caballeros with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Cheap flight deals from St. Louis to Santiago de los Caballeros

Most accurate provider

Most trusted provider

Round-trip from

Popular in

Cheapest in

Average price

Find flight deals from St. Louis to Santiago de los Caballeros

Cheapest flights from St. Louis to Santiago de los CaballerosExplore the most affordable flight options available from St. Louis to Santiago de los Caballeros. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 25, 2025.

Explore the most affordable flight options available from St. Louis to Santiago de los Caballeros. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 25, 2025.

Cheapflights Fare Finder

Use the filters below to find and compare flights from St. Louis to Santiago de los Caballeros that are best for you.

Compare providers for flights from St. Louis to Santiago de los Caballeros

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.

Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from St. Louis to Santiago de los Caballeros in September.

Best time to book a flight from St. Louis to Santiago de los Caballeros

Have a flexible travel schedule? Discover the best time to fly to Santiago de los Caballeros from St. Louis with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from St. Louis to Santiago de los Caballeros

What is the cheapest month to book a flight from St. Louis to Santiago de los Caballeros?

Reviews of airlines servicing Santiago de los Caballeros

Get a feel of what it's like to fly with American Airlines from St. Louis to Santiago de los Caballeros by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from St. Louis to Santiago de los Caballeros. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

How long is the flight from St. Louis to Santiago de los Caballeros?

What is the cheapest airline to fly from St. Louis to Santiago de los Caballeros round-trip?

Can I find deals for flights from St. Louis to Santiago de los Caballeros that include hotel bookings?

How can I find direct flights from St. Louis to Santiago de los Caballeros?

Can I find deals for business class flights from St. Louis to Santiago de los Caballeros?

What is the cheapest month to book a flight from St. Louis to Santiago de los Caballeros?

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for St. Louis to Santiago de los Caballeros

See prices for flight routes from nearby airports that may be better suited for you.

Top airline flying from St. Louis to Santiago de los Caballeros

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Travel Smart

Cheapest flights from St. Louis to Santiago de los Caballeros
Explore the most affordable flight options available from St. Louis to Santiago de los Caballeros. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 25, 2025.