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Santiago de los Caballeros

$432+ Cheap flights from St. Louis (STL) to Santiago de los Caballeros (STI)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/4. Fares are subject to change and may not be available on all flights or dates of travel.
STL — STI
Aug 19 — Aug 261
Tue 8/19
Tue 8/26
1 adult, Economy
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Cheap flight deals from St. Louis to Santiago de los Caballeros

Discover tips and strategies to find the most affordable flight options for your journey from St. Louis (STL) to Santiago de los Caballeros (STI). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated August 14, 2025.

Round-trip from

$432
(Kiwi.com)

Popular in

February

Cheapest in

September

Average price

$715
From Lambert-St Louis to Santiago de los Caballeros
Search Deals
Highest demand for flights based on searches. 11% potential increase in price ($91 potential increase over avg. RT price).
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Cheapest flight prices on average. 3% potential price decrease ($21 potential savings vs. average RT price).
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Average for round-trip flights in August 2025
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Find flight deals from St. Louis to Santiago de los Caballeros

Cheapest flights from St. Louis to Santiago de los Caballeros
Explore the most affordable flight options available from St. Louis to Santiago de los Caballeros. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 14, 2025.

This Kiwi.com deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/410:35 amSTL - STI
1 stop23h 28mMultiple Airlines
Sun 9/712:10 pmSTI - STL
2 stops27h 54mMultiple Airlines
Deal found 8/11$432
This Kiwi.com deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/39:32 pmSTL - STI
2 stops12h 31mMultiple Airlines
Sat 10/1112:13 pmSTI - STL
1 stop22h 49mMultiple Airlines
Deal found 8/13$443
This American Airlines deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/35:28 amSTL - STI
1 stop5h 59mAmerican Airlines
Sat 10/111:14 pmSTI - STL
1 stop11h 42mAmerican Airlines
Deal found 8/13$535
This American Airlines deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/45:28 amSTL - STI
1 stop5h 59mAmerican Airlines
Sat 10/111:14 pmSTI - STL
1 stop11h 42mAmerican Airlines
Deal found 8/12$555
This Delta deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/36:42 pmSTL - STI
2 stops16h 58mDelta
Sat 10/118:31 pmSTI - STL
2 stops19h 12mDelta
Deal found 8/12$559
This American Airlines deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/125:26 amSTL - STI
1 stop14h 22mAmerican Airlines
Mon 8/187:00 amSTI - STL
2 stops17h 14mAmerican Airlines
Deal found 8/11$629
This American Airlines deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/45:28 amSTL - STI
1 stop5h 59mAmerican Airlines
Sun 9/71:29 pmSTI - STL
1 stop11h 30mAmerican Airlines
Deal found 8/11$630

Cheapflights Fare Finder

 
Customize your flight search to find flights from St. Louis to Santiago de los Caballeros that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 14, 2025.
Use the filters below to find and compare flights from St. Louis to Santiago de los Caballeros that are best for you.

Fly from

St. Louis

Fly to

Santiago de los Caballeros

Route

Depart

Return

Price

St. LouisSantiago de los Caballeros

STL - STI

STLSTI

Lambert-St Louis

Thu 9/4

10:35 am-11:03 am

1 stop23h 28m

Santiago de los Caballeros

Sun 9/7

12:10 pm-3:04 pm

2 stops27h 54m

$432

St. LouisSantiago de los Caballeros

STL - STI

STLSTI

Lambert-St Louis

Fri 10/3

9:32 pm-11:03 am

2 stops12h 31m

Santiago de los Caballeros

Sat 10/11

12:13 pm-10:02 am

1 stop22h 49m

$443

St. LouisSantiago de los Caballeros

STL - STI

STLSTI

Lambert-St Louis

Fri 10/3

5:28 am-12:27 pm

1 stop5h 59m

Santiago de los Caballeros

Sat 10/11

1:14 pm-11:56 pm

1 stop11h 42m

$535

St. LouisSantiago de los Caballeros

STL - STI

STLSTI

Lambert-St Louis

Sat 10/4

5:28 am-12:27 pm

1 stop5h 59m

Santiago de los Caballeros

Sat 10/11

1:14 pm-11:56 pm

1 stop11h 42m

$555

St. LouisSantiago de los Caballeros

STL - STI

STLSTI

Lambert-St Louis

Fri 10/3

6:42 pm-12:40 pm

2 stops16h 58m

Santiago de los Caballeros

Sat 10/11

8:31 pm-2:43 pm

2 stops19h 12m

$559

St. LouisSantiago de los Caballeros

STL - STI

STLSTI

Lambert-St Louis

Sat 10/4

10:40 am-12:34 am

2 stops12h 54m

Santiago de los Caballeros

Sat 10/11

6:00 am-4:43 pm

1 stop11h 43m

$559

Flights are sorted by cheapest round-trip flights first.

Deals found on 8/11

Best time to book a flight from St. Louis to Santiago de los Caballeros

Have a flexible travel schedule? Discover the best time to fly to Santiago de los Caballeros from St. Louis with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from St. Louis to Santiago de los Caballeros

What is the cheapest month to book a flight from St. Louis to Santiago de los Caballeros?

Currently, May is the cheapest month in which you can book a flight from St. Louis to Santiago de los Caballeros (average of $347). Flying from St. Louis to Santiago de los Caballeros in July is currently the most expensive (average of $601). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Santiago de los Caballeros

Get insights into the airlines that provide service to Santiago de los Caballeros. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santiago de los Caballeros. Reviews last updated August 14, 2025.
Get a feel of what it's like to fly with American Airlines from St. Louis to Santiago de los Caballeros by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.2
Good
10,000 reviews

Crew

8.0

Comfort

7.2

Boarding

7.5

Food

6.5

Entertainment

6.9

Overall

7.2

Reviews

1 / 20
2.0
Mediocre

Anonymous,Aug 2025

MIA - DCA

Flight delayed 5 hours and was told it was due to mechanical issues. Instead of providing lodging due to missed connecting flight, American changed the cause of delay to weather, which meant they were not able required to provide a hotel. To make matters worse, one of our checked bags was lost even though its status said it was “by the plane” but no one at the service desk seemed able to locate it.
American Airlines
7.2
Good
10,000 reviews
American Airlines
7.2
Good
10,000 reviews

Crew

8.0

Comfort

7.2

Boarding

7.5

Food

6.5

Entertainment

6.9

Overall

7.2

Reviews

1 / 20
2.0
Mediocre

Anonymous,Aug 2025

MIA - DCA

Flight delayed 5 hours and was told it was due to mechanical issues. Instead of providing lodging due to missed connecting flight, American changed the cause of delay to weather, which meant they were not able required to provide a hotel. To make matters worse, one of our checked bags was lost even though its status said it was “by the plane” but no one at the service desk seemed able to locate it.

Related info for your journey

Find useful and relevant information for your journey from St. Louis to Santiago de los Caballeros. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What is the cheapest airline to fly from St. Louis to Santiago de los Caballeros round-trip?

    According to our current data, American Airlines ($633), offers the cheapest pricing from St. Louis to Santiago de los Caballeros. American Airlines is currently priced 7% below the average price you’ll pay for this route.

  • Can I find deals for flights from St. Louis to Santiago de los Caballeros that include hotel bookings?

    Yes. In addition to deals on St. Louis to Santiago de los Caballeros flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from St. Louis to Santiago de los Caballeros?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from St. Louis to Santiago de los Caballeros.

  • Can I find deals for business class flights from St. Louis to Santiago de los Caballeros?

    Yes. Cheapflights offers flight deals from St. Louis to Santiago de los Caballeros by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from St. Louis to Santiago de los Caballeros?

    Currently, May is the cheapest month in which you can book a flight from St. Louis to Santiago de los Caballeros (average of $347). Flying from St. Louis to Santiago de los Caballeros in July is currently the most expensive (average of $601). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Top airline flying from St. Louis to Santiago de los Caballeros

Discover the top airline that operate flights from St. Louis to Santiago de los Caballeros. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 14, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$633Average$864FlexibilityNo cancel feeOn-time71%

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