$236+ Cheap flights from St. Louis (STL) to Santo Domingo (SDQ)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/2. Fares are subject to change and may not be available on all flights or dates of travel.
STL — SDQ
May 25 — Jun 11
Round-trip
1 adult, Economy
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Find cheap flights from St. Louis to Santo Domingo with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from St. Louis to Santo Domingo
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Best
Last-minute
One-way
Cheapest flights from St. Louis to Santo DomingoExplore the most affordable flight options available from St. Louis to Santo Domingo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 25, 2026.
Explore the most affordable flight options available from St. Louis to Santo Domingo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 25, 2026.
This CheapOair deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/286:33 pm
STL
- SDQ
2 stops42h 06m
Frontier
Thu 6/410:58 am
SDQ
- STL
2 stops51h 57m
Frontier
Deal found 4/24![Frontier logo]()
$485
This CheapOair deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/305:27 pm
STL
- SDQ
2 stops19h 12m
Frontier
Sun 6/2811:55 am
SDQ
- STL
2 stops31h 23m
Frontier
Deal found 4/21![Frontier logo]()
$544
This CheapOair deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/46:33 pm
STL
- SDQ
2 stops39h 32m
Frontier
Sun 6/2811:55 am
SDQ
- STL
2 stops31h 23m
Frontier
Deal found 4/21![Frontier logo]()
$547
This CheapOair deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/26:33 pm
STL
- SDQ
2 stops39h 32m
Frontier
Fri 6/2612:21 pm
SDQ
- STL
2 stops31h 13m
Frontier
Deal found 4/21![Frontier logo]()
$549
This Delta deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/256:00 am
STL
- SDQ
1 stop17h 41m
Delta
Tue 6/26:05 am
SDQ
- STL
2 stops18h 54m
Delta
Deal found 4/21![Delta logo]()
$581
This CheapOair deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/295:27 pm
STL
- SDQ
2 stops19h 12m
Frontier
Fri 6/1212:21 pm
SDQ
- STL
2 stops31h 13m
Frontier
Deal found 4/21![Frontier logo]()
$587
This Delta deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/26:30 pm
STL
- SDQ
1 stop16h 55m
Delta
Wed 12/96:45 am
SDQ
- STL
1 stop16h 06m
Delta
Deal found 4/24![Delta logo]()
$590
This American Airlines deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/25:15 am
STL
- SDQ
1 stop16h 40m
American Airlines
Fri 6/267:00 am
SDQ
- STL
1 stop16h 58m
American Airlines
Deal found 4/21![American Airlines logo]()
$599
This Delta deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/36:30 pm
STL
- SDQ
1 stop16h 55m
Delta
Fri 12/113:55 pm
SDQ
- STL
1 stop9h 44m
Delta
Deal found 4/24![Delta logo]()
$610
This Delta deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/510:45 am
STL
- SDQ
2 stops12h 50m
Delta
Thu 12/103:55 pm
SDQ
- STL
1 stop9h 44m
Delta
Deal found 4/24![Delta logo]()
$615
Best flights from St. Louis to Santo DomingoDiscover carefully curated flight deals from St. Louis to Santo Domingo that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 25, 2026.
Discover carefully curated flight deals from St. Louis to Santo Domingo that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 25, 2026.
This Delta deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/256:00 am
STL
- SDQ
1 stop17h 41m
Delta
Tue 6/26:05 am
SDQ
- STL
2 stops18h 54m
Delta
Deal found 4/21![Delta logo]()
$581
This American Airlines deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/275:08 am
STL
- SDQ
2 stops12h 27m
American Airlines
Thu 8/67:39 pm
SDQ
- STL
1 stop16h 06m
American Airlines
Deal found 4/24![American Airlines logo]()
$595
This American Airlines deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/192:55 pm
STL
- SDQ
2 stops17h 30m
American Airlines
Mon 8/247:39 pm
SDQ
- STL
1 stop16h 06m
American Airlines
Deal found 4/23![American Airlines logo]()
$615
This Delta deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/66:45 am
STL
- SDQ
2 stops16h 56m
Delta
Thu 7/27:35 pm
SDQ
- STL
2 stops20h 05m
Delta
Deal found 4/21![Delta logo]()
$655
This American Airlines deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/15:33 am
STL
- SDQ
1 stop7h 47m
American Airlines
Sun 10/48:00 am
SDQ
- STL
2 stops15h 24m
American Airlines
Deal found 4/20![American Airlines logo]()
$620
This Delta deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/46:00 am
STL
- SDQ
1 stop6h 23m
Delta
Wed 7/12:41 pm
SDQ
- STL
1 stop10h 15m
Delta
Deal found 4/21![Delta logo]()
$670
This American Airlines deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/295:40 pm
STL
- SDQ
1 stop18h 05m
American Airlines
Sun 5/311:45 pm
SDQ
- STL
1 stop11h 14m
American Airlines
Deal found 4/22![American Airlines logo]()
$635
This Delta deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/106:00 am
STL
- SDQ
1 stop6h 12m
Delta
Tue 8/112:37 pm
SDQ
- STL
1 stop10h 00m
Delta
Deal found 4/20![Delta logo]()
$670
This American Airlines deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/286:00 am
STL
- SDQ
2 stops11h 35m
American Airlines
Thu 6/47:35 pm
SDQ
- STL
1 stop16h 00m
American Airlines
Deal found 4/24![American Airlines logo]()
$635
This American Airlines deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/145:24 am
STL
- SDQ
1 stop16h 31m
American Airlines
Tue 5/196:00 am
SDQ
- STL
2 stops12h 03m
American Airlines
Deal found 4/20![American Airlines logo]()
$640
Last-minute flights from St. Louis to Santo DomingoDiscover last-minute flight deals from St. Louis to Santo Domingo. Data last updated April 25, 2026 and is based on user searches.
Discover last-minute flight deals from St. Louis to Santo Domingo. Data last updated April 25, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/145:24 am
STL
- SDQ
1 stop6h 54m
American Airlines
Tue 5/196:00 am
SDQ
- STL
1 stop17h 24m
American Airlines
Deal found 4/21![American Airlines logo]()
$635
This American Airlines deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/165:24 am
STL
- SDQ
1 stop7h 03m
American Airlines
Fri 6/51:45 pm
SDQ
- STL
1 stop11h 14m
American Airlines
Deal found 4/21![American Airlines logo]()
$655
This Delta deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/256:00 am
STL
- SDQ
1 stop17h 41m
Delta
Tue 6/26:05 am
SDQ
- STL
1 stop15h 34m
Delta
Deal found 4/21![Delta logo]()
$581
This American Airlines deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/275:40 pm
STL
- SDQ
1 stop18h 05m
American Airlines
Thu 8/67:39 pm
SDQ
- STL
1 stop16h 06m
American Airlines
Deal found 4/24![American Airlines logo]()
$590
This CheapOair deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/286:33 pm
STL
- SDQ
2 stops42h 06m
Frontier
Thu 6/410:58 am
SDQ
- STL
2 stops51h 57m
Frontier
Deal found 4/24![Frontier logo]()
$485
This CheapOair deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/295:27 pm
STL
- SDQ
2 stops19h 12m
Frontier
Fri 6/1212:21 pm
SDQ
- STL
2 stops31h 13m
Frontier
Deal found 4/21![Frontier logo]()
$587
This American Airlines deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/295:40 pm
STL
- SDQ
1 stop18h 05m
American Airlines
Fri 6/121:45 pm
SDQ
- STL
1 stop11h 14m
American Airlines
Deal found 4/21![American Airlines logo]()
$619
This American Airlines deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/295:40 pm
STL
- SDQ
1 stop18h 05m
American Airlines
Mon 8/107:39 pm
SDQ
- STL
1 stop16h 06m
American Airlines
Deal found 4/21![American Airlines logo]()
$630
This CheapOair deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/305:27 pm
STL
- SDQ
2 stops19h 12m
Frontier
Sun 6/2811:55 am
SDQ
- STL
2 stops31h 23m
Frontier
Deal found 4/21![Frontier logo]()
$544
One-way flights from St. Louis to Santo DomingoSearch for one-way flight options from St. Louis to Santo Domingo. Find affordable one-way fares based on user searches. Data last updated April 25, 2026.
Search for one-way flight options from St. Louis to Santo Domingo. Find affordable one-way fares based on user searches. Data last updated April 25, 2026.
This eDestinos deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/26:33 pm
STL
- SDQ
2 stops39h 32m
Frontier
Deal found 4/21![Frontier logo]()
$236
This Kiwi.com deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/305:27 pm
STL
- SDQ
2 stops46h 02m
Multiple Airlines
Deal found 4/21![Multiple Airlines logo]()
$263
This Kiwi.com deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/105:33 pm
STL
- SDQ
2 stops45h 56m
Multiple Airlines
Deal found 4/20![Multiple Airlines logo]()
$271
This Kiwi.com deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/48:17 pm
STL
- SDQ
3 stops43h 12m
Multiple Airlines
Deal found 4/21![Multiple Airlines logo]()
$288
This Delta deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/2710:19 am
STL
- SDQ
2 stops13h 22m
Delta
Deal found 4/24![Delta logo]()
$343
This Delta deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/106:00 am
STL
- SDQ
1 stop6h 24m
Delta
Deal found 4/21![Delta logo]()
$363
This Delta deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/46:00 am
STL
- SDQ
1 stop6h 12m
Delta
Deal found 4/21![Delta logo]()
$393
Find flight deals from St. Louis to Santo Domingo
Discover tips and strategies to find the most affordable flight options for your journey from St. Louis (STL) to Santo Domingo (SDQ). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated April 25, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $485 (CheapOair) |
One-way from | $236 (eDestinos) |
Popular in | November |
Cheapest in | September |
Average price | $642 |
Cheapflights Fare Finder
Customize your flight search to find flights from St. Louis to Santo Domingo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 25, 2026.
Use the filters below to find and compare flights from St. Louis to Santo Domingo that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
St. LouisSanto Domingo
STL - SDQ
STLSDQ
Lambert-St Louis
Mon 5/25
6:00 am-12:41 am
1 stop17h 41m
Santo Domingo Las Americas
Tue 6/2
6:05 am-11:59 pm
2 stops18h 54m
$581
St. LouisSanto Domingo
STL - SDQ
STLSDQ
Lambert-St Louis
Wed 5/27
5:08 am-6:35 pm
2 stops12h 27m
Santo Domingo Las Americas
Thu 8/6
7:39 pm-10:45 am
1 stop16h 06m
$595
St. LouisSanto Domingo
STL - SDQ
STLSDQ
Lambert-St Louis
Wed 8/19
2:55 pm-9:25 am
2 stops17h 30m
Santo Domingo Las Americas
Mon 8/24
7:39 pm-10:45 am
1 stop16h 06m
$615
St. LouisSanto Domingo
STL - SDQ
STLSDQ
Lambert-St Louis
Thu 10/1
5:33 am-2:20 pm
1 stop7h 47m
Santo Domingo Las Americas
Sun 10/4
8:00 am-10:24 pm
2 stops15h 24m
$620
St. LouisSanto Domingo
STL - SDQ
STLSDQ
Lambert-St Louis
Fri 5/29
5:40 pm-12:45 pm
1 stop18h 05m
Santo Domingo Las Americas
Sun 5/31
1:45 pm-11:59 pm
1 stop11h 14m
$635
St. LouisSanto Domingo
STL - SDQ
STLSDQ
Lambert-St Louis
Thu 5/28
6:00 am-6:35 pm
2 stops11h 35m
Santo Domingo Las Americas
Thu 6/4
7:35 pm-10:35 am
1 stop16h 00m
$635
St. LouisSanto Domingo
STL - SDQ
STLSDQ
Lambert-St Louis
Thu 5/14
5:24 am-10:55 pm
1 stop16h 31m
Santo Domingo Las Americas
Tue 5/19
6:00 am-5:03 pm
2 stops12h 03m
$640
St. LouisSanto Domingo
STL - SDQ
STLSDQ
Lambert-St Louis
Sat 6/6
6:45 am-12:41 am
2 stops16h 56m
Santo Domingo Las Americas
Thu 7/2
7:35 pm-2:40 pm
2 stops20h 05m
$655
St. LouisSanto Domingo
STL - SDQ
STLSDQ
Lambert-St Louis
Thu 6/4
6:00 am-1:23 pm
1 stop6h 23m
Santo Domingo Las Americas
Wed 7/1
2:41 pm-11:56 pm
1 stop10h 15m
$670
Quickest round-trip
St. LouisSanto Domingo
STL - SDQ
STLSDQ
Lambert-St Louis
Mon 8/10
6:00 am-1:12 pm
1 stop6h 12m
Santo Domingo Las Americas
Tue 8/11
2:37 pm-11:37 pm
1 stop10h 00m
$670
Showing 1-10 of 18 resultsSorted by cheapest first
Compare providers for flights from St. Louis to Santo Domingo
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from St. Louis to Santo Domingo in April.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy2 stars | Trust Score*2 stars | |
| Price Accuracy2 stars | Trust Score*3 stars | |
| Price Accuracy- | Trust Score*1 star |
- Most accurate provider: When it comes to deals on St. Louis-Santo Domingo flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on St. Louis-Santo Domingo flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from St. Louis-Santo Domingo flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on St. Louis-Santo Domingo flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for St. Louis-Santo Domingo flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from St. Louis to Santo Domingo
Have a flexible travel schedule? Discover the best time to fly to Santo Domingo from St. Louis with our price prediction graph.
STL-SDQ
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from St. Louis to Santo Domingo
What is the cheapest month to book a flight from St. Louis to Santo Domingo?
Currently, September is the cheapest month in which you can book a flight from St. Louis to Santo Domingo (average of $542). Flying from St. Louis to Santo Domingo in November is currently the most expensive (average of $826). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from St. Louis to Santo Domingo?
Reviews of airlines servicing Santo Domingo
Get insights into the airlines that provide service to Santo Domingo. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santo Domingo. Reviews last updated April 25, 2026.
Read through reviews of airlines operating flights from St. Louis to Santo Domingo, such as Delta and American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Comfort
7.9
Crew
8.5
Entertainment
7.8
Overall
7.9
Boarding
8.1
Food
7.2
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Comfort
7.9
Crew
8.5
Entertainment
7.8
Overall
7.9
Boarding
8.1
Food
7.2
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Comfort
7.9
Crew
8.5
Entertainment
7.8
Overall
7.9
Boarding
8.1
Food
7.2
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Related info for your journey
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Top 2 airlines flying from St. Louis to Santo Domingo
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| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$524 | Average$641 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$529 | Average$687 | FlexibilityNo cancel fee | On-time71% |