$827+ Cheap flights from St. Louis (STL) to Santiago de los Caballeros (STI)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/5. Fares are subject to change and may not be available on all flights or dates of travel.
STL — STI
Dec 11 — Dec 181
Round-trip
1 adult, Economy
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Find cheap flights from St. Louis to Santiago de los Caballeros with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from St. Louis to Santiago de los Caballeros
Cheapest
Best
Last-minute
Cheapest flights from St. Louis to Santiago de los CaballerosExplore the most affordable flight options available from St. Louis to Santiago de los Caballeros. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 11, 2026.
Explore the most affordable flight options available from St. Louis to Santiago de los Caballeros. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 11, 2026.
This Flysmarter deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Flysmarter is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/245:03 am -
1 stop14h 59m
Sat 1/97:18 am -
1 stop18h 28m
Deal found 11/8![British Airways logo]()
$1,294
This Expedia deal was found by Cheapflights users on 11/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/216:20 am -
2 stops18h 24m
Wed 1/136:38 am -
2 stops18h 48m
Deal found 11/7![Delta logo]()
$1,585
This Flysmarter deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Flysmarter is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/245:08 pm -
2 stops16h 41m
Sat 1/912:55 pm -
2 stops12h 25m
Deal found 11/8![Lufthansa logo]()
$1,595
This Expedia deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/246:00 am -
2 stops18h 44m
Sat 1/98:44 pm -
2 stops19h 54m
Deal found 11/8![Delta logo]()
$1,633
This Expedia deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/248:22 am -
2 stops52h 36m
Sat 1/91:30 pm -
2 stops51h 56m
Deal found 11/8![Multiple Airlines logo]()
$2,541
Best flights from St. Louis to Santiago de los CaballerosDiscover carefully curated flight deals from St. Louis to Santiago de los Caballeros that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated November 11, 2026.
Discover carefully curated flight deals from St. Louis to Santiago de los Caballeros that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated November 11, 2026.
This American Airlines deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/512:21 pm -
1 stop23h 02m
Mon 4/121:32 pm -
2 stops29h 32m
Deal found 11/11![American Airlines logo]()
$827
This United Airlines deal was found by Cheapflights users on 11/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/24:57 pm -
1 stop16h 52m
Fri 2/56:00 am -
1 stop12h 16m
Deal found 11/7![United Airlines logo]()
$874
This Flysmarter deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Flysmarter is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/245:03 am -
1 stop14h 59m
Sat 1/97:18 am -
1 stop18h 28m
Deal found 11/8![British Airways logo]()
$1,294
This Expedia deal was found by Cheapflights users on 11/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/216:20 am -
2 stops18h 24m
Wed 1/136:38 am -
2 stops18h 48m
Deal found 11/7![Delta logo]()
$1,585
This American Airlines deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/75:24 am -
1 stop5h 59m
Mon 4/121:32 pm -
1 stop20h 48m
Deal found 11/11![American Airlines logo]()
$843
This American Airlines deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/91:29 pm -
2 stops21h 54m
Mon 4/121:32 pm -
2 stops29h 32m
Deal found 11/11![American Airlines logo]()
$867
This United Airlines deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/277:00 am -
2 stops14h 51m
Sat 4/36:00 am -
1 stop18h 25m
Deal found 11/10![United Airlines logo]()
$1,092
Last-minute flights from St. Louis to Santiago de los CaballerosDiscover last-minute flight deals from St. Louis to Santiago de los Caballeros. Data last updated November 11, 2026 and is based on user searches.
Discover last-minute flight deals from St. Louis to Santiago de los Caballeros. Data last updated November 11, 2026 and is based on user searches.
This Expedia deal was found by Cheapflights users on 11/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/216:20 am -
2 stops18h 24m
Wed 1/136:38 am -
2 stops18h 48m
Deal found 11/7![Delta logo]()
$1,585
This Flysmarter deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Flysmarter is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/245:03 am -
1 stop14h 59m
Sat 1/97:18 am -
1 stop18h 28m
Deal found 11/8![British Airways logo]()
$1,294
This Flysmarter deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Flysmarter is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/245:08 pm -
2 stops16h 41m
Sat 1/912:55 pm -
2 stops12h 25m
Deal found 11/8![Lufthansa logo]()
$1,595
This Expedia deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/246:00 am -
2 stops18h 44m
Sat 1/98:44 pm -
2 stops19h 54m
Deal found 11/8![Delta logo]()
$1,633
This Expedia deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/248:22 am -
2 stops52h 36m
Sat 1/91:30 pm -
2 stops51h 56m
Deal found 11/8![Multiple Airlines logo]()
$2,541
Find flight deals from St. Louis to Santiago de los Caballeros
Discover tips and strategies to find the most affordable flight options for your journey from St. Louis (STL) to Santiago de los Caballeros (STI). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated November 11, 2026.
Most accurate provider | Ovago 3 stars |
|---|---|
Most trusted provider | Ovago 3 stars |
Round-trip from | $874 (United Airlines) |
Cheapflights Fare Finder
Customize your flight search to find flights from St. Louis to Santiago de los Caballeros that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated November 11, 2026.
Use the filters below to find and compare flights from St. Louis to Santiago de los Caballeros that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
St. LouisSantiago de los Caballeros
STL Lambert-St Louis - STI Santiago de los Caballeros
STLSTI
Lambert-St Louis
Mon 4/5
12:21 pm-12:23 pm
1 stop23h 02m
Santiago de los Caballeros
Mon 4/12
1:32 pm-6:04 pm
2 stops29h 32m
$827
Quickest round-trip
St. LouisSantiago de los Caballeros
STL Lambert-St Louis - STI Santiago de los Caballeros
STLSTI
Lambert-St Louis
Wed 4/7
5:24 am-12:23 pm
1 stop5h 59m
Santiago de los Caballeros
Mon 4/12
1:32 pm-9:20 am
1 stop20h 48m
$843
St. LouisSantiago de los Caballeros
STL Lambert-St Louis - STI Santiago de los Caballeros
STLSTI
Lambert-St Louis
Fri 4/9
1:29 pm-12:23 pm
2 stops21h 54m
Santiago de los Caballeros
Mon 4/12
1:32 pm-6:04 pm
2 stops29h 32m
$867
St. LouisSantiago de los Caballeros
STL Lambert-St Louis - STI Santiago de los Caballeros
STLSTI
Lambert-St Louis
Tue 2/2
4:57 pm-11:49 am
1 stop16h 52m
Santiago de los Caballeros
Fri 2/5
6:00 am-4:16 pm
1 stop12h 16m
$874
St. LouisSantiago de los Caballeros
STL Lambert-St Louis - STI Santiago de los Caballeros
STLSTI
Lambert-St Louis
Sat 3/27
7:00 am-10:51 pm
2 stops14h 51m
Santiago de los Caballeros
Sat 4/3
6:00 am-11:25 pm
1 stop18h 25m
$1,092
St. LouisSantiago de los Caballeros
STL Lambert-St Louis - STI Santiago de los Caballeros
STLSTI
Lambert-St Louis
Thu 12/24
5:03 am-10:02 pm
1 stop14h 59m
Santiago de los Caballeros
Sat 1/9
7:18 am-11:46 pm
1 stop18h 28m
$1,294
St. LouisSantiago de los Caballeros
STL Lambert-St Louis - STI Santiago de los Caballeros
STLSTI
Lambert-St Louis
Mon 12/21
6:20 am-2:44 am
2 stops18h 24m
Santiago de los Caballeros
Wed 1/13
6:38 am-11:26 pm
2 stops18h 48m
$1,585
Sorted by cheapest first
Compare providers for flights from St. Louis to Santiago de los Caballeros
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from St. Louis to Santiago de los Caballeros in November.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy2 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on St. Louis-Santiago de los Caballeros flights, users find the pricing of Ovago to be most consistent on Cheapflights vs. Ovago Users can find the same prices on St. Louis-Santiago de los Caballeros flight deals on Cheapflights vs. Ovago >95% of the time. Price accuracy is based on data collected from St. Louis-Santiago de los Caballeros flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on St. Louis-Santiago de los Caballeros flights, Cheapflights users trust Ovago the most. Ovago has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for St. Louis-Santiago de los Caballeros flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from St. Louis to Santiago de los Caballeros
Have a flexible travel schedule? Discover the best time to fly to Santiago de los Caballeros from St. Louis with our price prediction graph.
STL-STI
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Reviews of airlines servicing Santiago de los Caballeros
Get insights into the airlines that provide service to Santiago de los Caballeros. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santiago de los Caballeros. Reviews last updated November 11, 2026.
Get a feel of what it's like to fly with United Airlines from St. Louis to Santiago de los Caballeros by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Comfort
7.3
Entertainment
7.1
Boarding
7.7
Crew
8.1
Overall
7.3
Food
6.7
Reviews
1 / 20
8.0
ExcellentAsha,Sep 2026
LGA - IAH
Comfort
7.3
Entertainment
7.1
Boarding
7.7
Crew
8.1
Overall
7.3
Food
6.7
Reviews
1 / 20
8.0
ExcellentAsha,Sep 2026
LGA - IAH
Related info for your journey
Find useful and relevant information for your journey from St. Louis to Santiago de los Caballeros. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Santiago de los Caballeros flight routes
Alternative routes for St. Louis to Santiago de los Caballeros
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Complete your trip
Complete your trip to Santiago de los Caballeros by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from St. Louis to Santiago de los Caballeros by cabin class
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St. Louis and Santiago de los Caballeros flights
Browse other St. Louis and Santiago de los Caballeros flight options. Last updated on November 11, 2026.
Other flights from St. Louis
Browse through other flights departing from St. Louis. Flights are based on user searches made on Cheapflights and were last updated on November 11, 2026.
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Other flights to Santiago de los Caballeros
Explore flights to Santiago de los Caballeros departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on November 11, 2026.
Top airline flying from St. Louis to Santiago de los Caballeros
Discover the top airline that operate flights from St. Louis to Santiago de los Caballeros. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated November 11, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$538 | Average$690 | FlexibilityNo cancel fee | On-time69% |