$300+ Cheap flights from St. Louis (STL) to Santiago de los Caballeros (STI)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/27. Fares are subject to change and may not be available on all flights or dates of travel.
STL — STI
Aug 7 — Aug 141
Round-trip
1 adult, Economy
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Find cheap flights from St. Louis to Santiago de los Caballeros with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from St. Louis to Santiago de los Caballeros
Cheapest
Best
Last-minute
One-way
Cheapest flights from St. Louis to Santiago de los CaballerosExplore the most affordable flight options available from St. Louis to Santiago de los Caballeros. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 8, 2026.
Explore the most affordable flight options available from St. Louis to Santiago de los Caballeros. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 8, 2026.
This United Airlines deal was found by Cheapflights users on 7/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/87:00 am
STL
- STI
1 stop14h 52m
United Airlines
Sun 9/134:23 pm
STI
- STL
1 stop8h 15m
United Airlines
Deal found 7/6![United Airlines logo]()
$620
This American Airlines deal was found by Cheapflights users on 7/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/86:00 am
STL
- STI
2 stops13h 03m
American Airlines
Sun 9/133:15 pm
STI
- STL
2 stops20h 00m
American Airlines
Deal found 7/6![American Airlines logo]()
$630
This American Airlines deal was found by Cheapflights users on 7/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/1611:35 am
STL
- STI
1 stop8h 32m
American Airlines
Sun 8/237:00 am
STI
- STL
1 stop16h 40m
American Airlines
Deal found 7/4![American Airlines logo]()
$645
This United Airlines deal was found by Cheapflights users on 7/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/2212:28 pm
STL
- STI
1 stop9h 24m
United Airlines
Thu 9/246:00 am
STI
- STL
1 stop16h 09m
United Airlines
Deal found 7/5![United Airlines logo]()
$754
This United Airlines deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/81:13 pm
STL
- STI
2 stops24h 59m
United Airlines
Sun 7/196:00 am
STI
- STL
2 stops27h 39m
United Airlines
Deal found 7/8![United Airlines logo]()
$1,045
This American Airlines deal was found by Cheapflights users on 7/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/195:05 am
STL
- STI
1 stop7h 19m
American Airlines
Sun 12/202:32 pm
STI
- STL
1 stop8h 35m
American Airlines
Deal found 7/5![American Airlines logo]()
$1,182
Best flights from St. Louis to Santiago de los CaballerosDiscover carefully curated flight deals from St. Louis to Santiago de los Caballeros that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 8, 2026.
Discover carefully curated flight deals from St. Louis to Santiago de los Caballeros that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 8, 2026.
This United Airlines deal was found by Cheapflights users on 7/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/87:00 am
STL
- STI
1 stop14h 52m
United Airlines
Sun 9/134:23 pm
STI
- STL
1 stop8h 15m
United Airlines
Deal found 7/6![United Airlines logo]()
$620
This United Airlines deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/299:30 am
STL
- STI
1 stop12h 22m
United Airlines
Thu 10/16:00 am
STI
- STL
1 stop16h 09m
United Airlines
Deal found 7/7![United Airlines logo]()
$754
This United Airlines deal was found by Cheapflights users on 7/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/2212:28 pm
STL
- STI
1 stop9h 24m
United Airlines
Thu 9/246:00 am
STI
- STL
1 stop16h 09m
United Airlines
Deal found 7/6![United Airlines logo]()
$754
Last-minute flights from St. Louis to Santiago de los CaballerosDiscover last-minute flight deals from St. Louis to Santiago de los Caballeros. Data last updated July 8, 2026 and is based on user searches.
Discover last-minute flight deals from St. Louis to Santiago de los Caballeros. Data last updated July 8, 2026 and is based on user searches.
This United Airlines deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/85:59 pm
STL
- STI
2 stops17h 58m
United Airlines
Sun 7/194:23 pm
STI
- STL
1 stop8h 21m
United Airlines
Deal found 7/8![United Airlines logo]()
$1,045
This American Airlines deal was found by Cheapflights users on 7/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/1611:35 am
STL
- STI
1 stop8h 32m
American Airlines
Sun 8/237:00 am
STI
- STL
1 stop16h 40m
American Airlines
Deal found 7/4![American Airlines logo]()
$645
One-way flights from St. Louis to Santiago de los CaballerosSearch for one-way flight options from St. Louis to Santiago de los Caballeros. Find affordable one-way fares based on user searches. Data last updated July 8, 2026.
Search for one-way flight options from St. Louis to Santiago de los Caballeros. Find affordable one-way fares based on user searches. Data last updated July 8, 2026.
This American Airlines deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/2711:35 am
STL
- STI
1 stop8h 32m
American Airlines
Deal found 7/8![American Airlines logo]()
$300
This Delta deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/286:00 am
STL
- STI
2 stops12h 34m
Delta
Deal found 7/8![Delta logo]()
$332
This Delta deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/256:30 am
STL
- STI
2 stops12h 04m
Delta
Deal found 7/8![Delta logo]()
$343
This American Airlines deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/285:00 am
STL
- STI
1 stop8h 35m
American Airlines
Deal found 7/8![American Airlines logo]()
$360
This American Airlines deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/295:42 pm
STL
- STI
1 stop17h 40m
American Airlines
Deal found 7/8![American Airlines logo]()
$392
This United Airlines deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/2512:27 pm
STL
- STI
1 stop9h 25m
United Airlines
Deal found 7/8![United Airlines logo]()
$403
This Kiwi.com deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/256:45 pm
STL
- STI
3 stops43h 14m
Multiple Airlines
Deal found 7/8![Multiple Airlines logo]()
$604
This Kiwi.com deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/266:45 pm
STL
- STI
3 stops19h 14m
Multiple Airlines
Deal found 7/8![Multiple Airlines logo]()
$605
This Kiwi.com deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/296:45 pm
STL
- STI
3 stops43h 14m
Multiple Airlines
Deal found 7/8![Multiple Airlines logo]()
$628
This Kiwi.com deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/277:58 pm
STL
- STI
3 stops42h 01m
Multiple Airlines
Deal found 7/8![Multiple Airlines logo]()
$630
This Kiwi.com deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/287:58 pm
STL
- STI
3 stops18h 01m
Multiple Airlines
Deal found 7/8![Multiple Airlines logo]()
$637
This American Airlines deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/196:00 pm
STL
- STI
1 stop18h 24m
American Airlines
Deal found 7/7![American Airlines logo]()
$763
Find flight deals from St. Louis to Santiago de los Caballeros
Discover tips and strategies to find the most affordable flight options for your journey from St. Louis (STL) to Santiago de los Caballeros (STI). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated July 8, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $620 (United Airlines) |
One-way from | $300 (American Airlines) |
Cheapflights Fare Finder
Customize your flight search to find flights from St. Louis to Santiago de los Caballeros that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 8, 2026.
Use the filters below to find and compare flights from St. Louis to Santiago de los Caballeros that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
St. LouisSantiago de los Caballeros
STL - STI
STLSTI
Lambert-St Louis
Tue 9/8
7:00 am-10:52 pm
1 stop14h 52m
Santiago de los Caballeros
Sun 9/13
4:23 pm-11:38 pm
1 stop8h 15m
$620
St. LouisSantiago de los Caballeros
STL - STI
STLSTI
Lambert-St Louis
Tue 9/29
9:30 am-10:52 pm
1 stop12h 22m
Santiago de los Caballeros
Thu 10/1
6:00 am-9:09 pm
1 stop16h 09m
$754
St. LouisSantiago de los Caballeros
STL - STI
STLSTI
Lambert-St Louis
Tue 9/22
12:28 pm-10:52 pm
1 stop9h 24m
Santiago de los Caballeros
Thu 9/24
6:00 am-9:09 pm
1 stop16h 09m
$754
Cheapest one-way
St. LouisSantiago de los Caballeros
STL - STI
STLSTI
Lambert-St Louis
Thu 8/27
6:00 am-9:07 pm
2 stops14h 07m
$300
St. LouisSantiago de los Caballeros
STL - STI
STLSTI
Lambert-St Louis
Wed 8/26
10:33 am-1:55 am
2 stops14h 22m
$343
St. LouisSantiago de los Caballeros
STL - STI
STLSTI
Lambert-St Louis
Tue 8/25
6:30 am-7:34 pm
2 stops12h 04m
$343
Quickest one-way
St. LouisSantiago de los Caballeros
STL - STI
STLSTI
Lambert-St Louis
Tue 8/25
12:27 pm-10:52 pm
1 stop9h 25m
$403
St. LouisSantiago de los Caballeros
STL - STI
STLSTI
Lambert-St Louis
Sat 12/19
7:04 pm-2:53 pm
2 stops17h 49m
$819
Sorted by cheapest first
Compare providers for flights from St. Louis to Santiago de los Caballeros
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from St. Louis to Santiago de los Caballeros in July.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on St. Louis-Santiago de los Caballeros flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on St. Louis-Santiago de los Caballeros flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from St. Louis-Santiago de los Caballeros flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on St. Louis-Santiago de los Caballeros flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for St. Louis-Santiago de los Caballeros flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from St. Louis to Santiago de los Caballeros
Have a flexible travel schedule? Discover the best time to fly to Santiago de los Caballeros from St. Louis with our price prediction graph.
STL-STI
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Reviews of airlines servicing Santiago de los Caballeros
Get insights into the airlines that provide service to Santiago de los Caballeros. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santiago de los Caballeros. Reviews last updated July 8, 2026.
Get a feel of what it's like to fly with United Airlines from St. Louis to Santiago de los Caballeros by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.1
Overall
7.4
Entertainment
7.1
Boarding
7.7
Comfort
7.3
Food
6.7
Reviews
1 / 20
6.0
GoodROHIT,Jun 2026
IND - EWR
Crew
8.1
Overall
7.4
Entertainment
7.1
Boarding
7.7
Comfort
7.3
Food
6.7
Reviews
1 / 20
6.0
GoodROHIT,Jun 2026
IND - EWR
Related info for your journey
Find useful and relevant information for your journey from St. Louis to Santiago de los Caballeros. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
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Complete your trip
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Santiago de los Caballeros flight routes
Alternative routes for St. Louis to Santiago de los Caballeros
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Santiago de los Caballeros by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from St. Louis to Santiago de los Caballeros by cabin class
Find flights from St. Louis to Santiago de los Caballeros, based on your preferred cabin class, be it economy, premium economy, business, or first class.
St. Louis and Santiago de los Caballeros flights
Browse other St. Louis and Santiago de los Caballeros flight options. Last updated on July 8, 2026.
Other flights from St. Louis
Browse through other flights departing from St. Louis. Flights are based on user searches made on Cheapflights and were last updated on July 8, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Other flights to Santiago de los Caballeros
Explore flights to Santiago de los Caballeros departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on July 8, 2026.
Top airline flying from St. Louis to Santiago de los Caballeros
Discover the top airline that operate flights from St. Louis to Santiago de los Caballeros. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 8, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$538 | Average$617 | FlexibilityNo cancel fee | On-time69% |