$307+ Cheap flights from San Francisco (SFO) to Santiago (SCL)

A quick flight from San Francisco to Santiago can take about 18h 45m. Copa Airlines provides one of the quickest options available for as low as $504. There are 5918 mi between San Francisco and Santiago. Both multi-stop and nonstop flights can be found to your destination and back.

Currently priced at $492, Avianca will fly you from San Francisco to Santiago and back. In addition to Avianca, many other airlines offer competitively priced options for your trip. Search Cheapflights for deals from United Airlines and American Airlines - these airlines can fly you to your destination from $494 and $498, respectively. Avianca is currently priced 37% below the average price you’ll pay for this route.

$191 is the cheapest one-way deal found within the past few days, from Avianca. You may also be able to find cheap deals on Copa Airlines and American Airlines, with prices starting from $299 and $302, respectively.

Of the flights from San Francisco to Santiago that have layovers, most of them stop in Los Angeles. San Francisco to Santiago flights stop in Houston the next most. Atlanta comes next as the third most popular layover location for San Francisco to Santiago flights.

Hollywood Bowl, Hollywood Walk of Fame, and L.A. Live are currently the most popular points of interest in Los Angeles at the moment. Hollywood Bowl, Hollywood Walk of Fame and L.A. Live are located about 12.5 mi, 11.7 mi, and 10.8 mi, respectively from Los Angeles if you are interested in checking them out. Travelers in need of a car in Los Angeles can rent one for about $38 per day.

The majority of Houston visitors spend their time at Space Center Houston, House of Blues Houston, and Revention Music Center. Those on a layover in Houston interested in visiting Space Center Houston, House of Blues Houston, or Revention Music Center can do so by traveling 33.5 mi, 16.1 mi, and 15.5 mi, respectively from Houston George Bush Intcntl. Those looking to explore during their layover in Houston can rent a car from Houston George Bush Intcntl for about $38 per day.

Most Atlanta visitors opt to spend their time at Georgia Aquarium, Fox Theatre, and Centennial Olympic Park. Georgia Aquarium, Fox Theatre, and Centennial Olympic Park can be accessed by traveling approximately 8.6 mi, 9.3 mi, and 8.4 mi, respectively from Atlanta Hartsfield-Jackson. Travelers can book a car rental at Atlanta Hartsfield-Jackson for about $54 per day to make their sightseeing more efficient.

The least popular layover on flights from San Francisco to Santiago is Panama City. Dallas is the second least popular location for layovers on flights from San Francisco to Santiago.

Yes. In addition to deals on San Francisco to Santiago flights, Cheapflights offers vacation packages that include both flights and hotel.

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from San Francisco to Santiago.

Yes. Cheapflights offers flight deals from San Francisco to Santiago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

Currently, September is the cheapest month in which you can book a flight from San Francisco to Santiago (average of $475). Flying from San Francisco to Santiago in June is currently the most expensive (average of $663). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.