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$618+ Cheap flights from Medford (MFR) to Santiago (SCL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/30. Fares are subject to change and may not be available on all flights or dates of travel.
MFR — SCL
oct. 11 — oct. 181
sáb. 10/11
sáb. 10/18
1 adult, Economy
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Cheap flight deals from Medford to Santiago

Discover tips and strategies to find the most affordable flight options for your journey from Medford (MFR) to Santiago (SCL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated septiembre 11, 2025.

Round-trip from

$834
(Delta)

One-way from

$618
(Delta)
From Medford to Santiago Arturo Merino Benitez
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One-way flight from Medford to Santiago Arturo Merino Benitez
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Find flight deals from Medford to Santiago

Cheapest flights from Medford to Santiago
Explore the most affordable flight options available from Medford to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on septiembre 11, 2025.

This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 12/412:41 pmMFR - SCL
2 stops34h 49mDelta
lun. 12/88:20 amSCL - MFR
2 stops20h 39mDelta
Deal found 9/10$834
This Delta deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 11/35:15 amMFR - SCL
2 stops19h 45mDelta
jue. 11/1311:10 pmSCL - MFR
2 stops29h 20mDelta
Deal found 9/11$838

Cheapflights Fare Finder

 
Customize your flight search to find flights from Medford to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated septiembre 11, 2025.
Use the filters below to find and compare flights from Medford to Santiago that are best for you.

Fly from

Medford

Fly to

Santiago

Route

Depart

Return

Price

MedfordSantiago

MFR - SCL

MFRSCL

Medford

jue. 12/4

12:41 pm-4:30 am

2 stops34h 49m

Santiago Arturo Merino Benitez

lun. 12/8

8:20 am-11:59 pm

2 stops20h 39m

$834

MedfordSantiago

MFR - SCL

MFRSCL

Medford

lun. 11/3

6:00 am-8:50 am

2 stops21h 50m

Santiago Arturo Merino Benitez

jue. 11/13

10:45 pm-10:30 pm

3 stops28h 45m

$838

MedfordSantiago

MFR - SCL

MFRSCL

Medford

lun. 11/3

5:15 am-7:40 am

2 stops21h 25m

Santiago Arturo Merino Benitez

jue. 11/13

11:55 pm-11:56 pm

2 stops29h 01m

$838

MedfordSantiago

MFR - SCL

MFRSCL

Medford

vie. 1/23

8:35 am-7:00 am

2 stops41h 25m

Santiago Arturo Merino Benitez

sáb. 2/7

7:15 am-11:10 am

3 stops56h 55m

$4,491

MedfordSantiago

MFR - SCL

MFRSCL

Medford

mar. 9/30

6:15 am-6:50 am

2 stops20h 35m

$618

MedfordSantiago

MFR - SCL

MFRSCL

Medford

mar. 9/30

5:58 am-6:00 am

1 stop20h 02m

$618

MedfordSantiago

MFR - SCL

MFRSCL

Medford

sáb. 9/27

5:15 am-6:00 am

2 stops20h 45m

$658

MedfordSantiago

MFR - SCL

MFRSCL

Medford

sáb. 9/27

5:58 am-6:00 am

1 stop20h 02m

$658

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/10

Best time to book a flight from Medford to Santiago

Have a flexible travel schedule? Discover the best time to fly to Santiago from Medford with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Related info for your journey

Find useful and relevant information for your journey from Medford to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Medford to Santiago?

    There are many flights that can get you from Medford to Santiago in 21h 50m. Fly via Delta or United Airlines to get the fastest option. The distance between Medford and Santiago is about 6182 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • Can I find deals for flights from Medford to Santiago that include hotel bookings?

    Yes. In addition to deals on Medford to Santiago flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Medford to Santiago?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Medford to Santiago.

  • Can I find deals for business class flights from Medford to Santiago?

    Yes. Cheapflights offers flight deals from Medford to Santiago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Medford to Santiago?

    Currently, April is the cheapest month in which you can book a flight from Medford to Santiago (average of $752). Flying from Medford to Santiago in December is currently the most expensive (average of $1,098). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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