$315+ Cheap flights from Medford to Louisville (MFR - SDF)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/15. Fares are subject to change and may not be available on all flights or dates of travel.
MFR — SDF
May 27 — Jun 31
Round-trip
1 adult, Economy
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Find cheap flights from Medford to Louisville with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Medford to Louisville
Cheapest
Best
Last-minute
One-way
Cheapest flights from Medford to LouisvilleExplore the most affordable flight options available from Medford to Louisville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 27, 2026.
Explore the most affordable flight options available from Medford to Louisville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 27, 2026.
This United Airlines deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/2512:50 pm
MFR
- SDF
1 stop6h 49m
United Airlines
Sat 5/23:37 pm
SDF
- MFR
1 stop8h 54m
United Airlines
Deal found 4/25![United Airlines logo]()
$431
This United Airlines deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/221:10 pm
MFR
- SDF
1 stop6h 49m
United Airlines
Fri 5/293:25 pm
SDF
- MFR
2 stops10h 34m
United Airlines
Deal found 4/22![United Airlines logo]()
$454
This United Airlines deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/712:52 pm
MFR
- SDF
1 stop6h 39m
United Airlines
Mon 5/112:45 pm
SDF
- MFR
2 stops9h 46m
United Airlines
Deal found 4/22![United Airlines logo]()
$464
This Delta deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/106:01 am
MFR
- SDF
2 stops10h 10m
Delta
Tue 6/165:59 pm
SDF
- MFR
2 stops8h 58m
Delta
Deal found 4/26![Delta logo]()
$489
This Delta deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/245:28 pm
MFR
- SDF
2 stops13h 58m
Delta
Tue 6/301:02 pm
SDF
- MFR
2 stops13h 20m
Delta
Deal found 4/23![Delta logo]()
$544
This Alaska Airlines deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/287:08 am
MFR
- SDF
2 stops12h 11m
Alaska Airlines
Mon 6/11:21 pm
SDF
- MFR
2 stops13h 38m
Alaska Airlines
Deal found 4/26![Alaska Airlines logo]()
$582
This Alaska Airlines deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/127:16 pm
MFR
- SDF
2 stops12h 30m
Alaska Airlines
Sat 5/161:43 pm
SDF
- MFR
2 stops13h 16m
Alaska Airlines
Deal found 4/26![Alaska Airlines logo]()
$602
Best flights from Medford to LouisvilleDiscover carefully curated flight deals from Medford to Louisville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 27, 2026.
Discover carefully curated flight deals from Medford to Louisville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 27, 2026.
This United Airlines deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/221:10 pm
MFR
- SDF
1 stop6h 49m
United Airlines
Fri 5/293:25 pm
SDF
- MFR
2 stops10h 34m
United Airlines
Deal found 4/22![United Airlines logo]()
$454
This Delta deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/106:01 am
MFR
- SDF
2 stops10h 10m
Delta
Tue 6/165:59 pm
SDF
- MFR
2 stops8h 58m
Delta
Deal found 4/26![Delta logo]()
$489
This Alaska Airlines deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/287:08 am
MFR
- SDF
2 stops12h 11m
Alaska Airlines
Mon 6/11:21 pm
SDF
- MFR
2 stops13h 38m
Alaska Airlines
Deal found 4/26![Alaska Airlines logo]()
$582
This United Airlines deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/712:52 pm
MFR
- SDF
1 stop6h 39m
United Airlines
Mon 5/112:45 pm
SDF
- MFR
2 stops9h 46m
United Airlines
Deal found 4/22![United Airlines logo]()
$464
This Alaska Airlines deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/127:16 pm
MFR
- SDF
2 stops12h 30m
Alaska Airlines
Sat 5/161:43 pm
SDF
- MFR
2 stops13h 16m
Alaska Airlines
Deal found 4/26![Alaska Airlines logo]()
$602
This United Airlines deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/166:26 pm
MFR
- SDF
2 stops11h 49m
United Airlines
Mon 9/213:25 pm
SDF
- MFR
2 stops10h 16m
United Airlines
Deal found 4/22![United Airlines logo]()
$696
This United Airlines deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/121:10 pm
MFR
- SDF
1 stop6h 49m
United Airlines
Mon 6/153:25 pm
SDF
- MFR
1 stop8h 51m
United Airlines
Deal found 4/26![United Airlines logo]()
$698
This United Airlines deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/231:10 pm
MFR
- SDF
1 stop6h 49m
United Airlines
Tue 6/303:25 pm
SDF
- MFR
1 stop8h 51m
United Airlines
Deal found 4/26![United Airlines logo]()
$710
This United Airlines deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/281:10 pm
MFR
- SDF
1 stop6h 49m
United Airlines
Mon 6/15:20 am
SDF
- MFR
2 stops10h 45m
United Airlines
Deal found 4/26![United Airlines logo]()
$725
Last-minute flights from Medford to LouisvilleDiscover last-minute flight deals from Medford to Louisville. Data last updated April 27, 2026 and is based on user searches.
Discover last-minute flight deals from Medford to Louisville. Data last updated April 27, 2026 and is based on user searches.
This Delta deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/245:28 pm
MFR
- SDF
2 stops13h 58m
Delta
Tue 6/301:02 pm
SDF
- MFR
2 stops13h 20m
Delta
Deal found 4/23![Delta logo]()
$544
This United Airlines deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/2512:50 pm
MFR
- SDF
1 stop6h 49m
United Airlines
Sat 5/23:37 pm
SDF
- MFR
1 stop8h 54m
United Airlines
Deal found 4/25![United Airlines logo]()
$431
This United Airlines deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/712:52 pm
MFR
- SDF
1 stop6h 39m
United Airlines
Mon 5/112:45 pm
SDF
- MFR
2 stops9h 46m
United Airlines
Deal found 4/22![United Airlines logo]()
$464
This Alaska Airlines deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/77:41 pm
MFR
- SDF
2 stops12h 05m
Alaska Airlines
Mon 5/115:56 am
SDF
- MFR
2 stops9h 56m
Alaska Airlines
Deal found 4/22![Alaska Airlines logo]()
$619
This Alaska Airlines deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/127:16 pm
MFR
- SDF
2 stops12h 30m
Alaska Airlines
Sat 5/161:43 pm
SDF
- MFR
2 stops13h 16m
Alaska Airlines
Deal found 4/26![Alaska Airlines logo]()
$602
This United Airlines deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/221:10 pm
MFR
- SDF
1 stop6h 49m
United Airlines
Fri 5/293:25 pm
SDF
- MFR
2 stops10h 34m
United Airlines
Deal found 4/22![United Airlines logo]()
$454
This Alaska Airlines deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/287:08 am
MFR
- SDF
2 stops12h 11m
Alaska Airlines
Mon 6/11:21 pm
SDF
- MFR
2 stops13h 38m
Alaska Airlines
Deal found 4/26![Alaska Airlines logo]()
$582
One-way flights from Medford to LouisvilleSearch for one-way flight options from Medford to Louisville. Find affordable one-way fares based on user searches. Data last updated April 27, 2026.
Search for one-way flight options from Medford to Louisville. Find affordable one-way fares based on user searches. Data last updated April 27, 2026.
This Delta deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/156:00 am
MFR
- SDF
2 stops10h 13m
Delta
Deal found 4/24![Delta logo]()
$315
This United Airlines deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/151:10 pm
MFR
- SDF
1 stop6h 49m
United Airlines
Deal found 4/24![United Airlines logo]()
$325
This Kiwi.com deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/157:50 pm
MFR
- SDF
3 stops24h 28m
Multiple Airlines
Deal found 4/24![Multiple Airlines logo]()
$839
Find flight deals from Medford to Louisville
Discover tips and strategies to find the most affordable flight options for your journey from Medford (MFR) to Louisville (SDF). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated April 27, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $454 (United Airlines) |
One-way from | $315 (Delta) |
Popular in | May |
Cheapest in | December |
Average price | $482 |
Cheapflights Fare Finder
Customize your flight search to find flights from Medford to Louisville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 27, 2026.
Use the filters below to find and compare flights from Medford to Louisville that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
MedfordLouisville
MFR - SDF
MFRSDF
Medford
Fri 5/22
1:10 pm-10:59 pm
1 stop6h 49m
Louisville Intl
Fri 5/29
3:25 pm-10:59 pm
2 stops10h 34m
$454
MedfordLouisville
MFR - SDF
MFRSDF
Medford
Thu 5/7
12:52 pm-10:31 pm
1 stop6h 39m
Louisville Intl
Mon 5/11
2:45 pm-9:31 pm
2 stops9h 46m
$464
MedfordLouisville
MFR - SDF
MFRSDF
Medford
Wed 6/10
6:01 am-7:11 pm
2 stops10h 10m
Louisville Intl
Tue 6/16
5:59 pm-11:57 pm
2 stops8h 58m
$489
MedfordLouisville
MFR - SDF
MFRSDF
Medford
Thu 5/28
7:08 am-10:19 pm
2 stops12h 11m
Louisville Intl
Mon 6/1
1:21 pm-11:59 pm
2 stops13h 38m
$582
MedfordLouisville
MFR - SDF
MFRSDF
Medford
Tue 5/12
7:16 pm-10:46 am
2 stops12h 30m
Louisville Intl
Sat 5/16
1:43 pm-11:59 pm
2 stops13h 16m
$602
MedfordLouisville
MFR - SDF
MFRSDF
Medford
Wed 9/16
6:26 pm-9:15 am
2 stops11h 49m
Louisville Intl
Mon 9/21
3:25 pm-10:41 pm
2 stops10h 16m
$696
Quickest round-trip
MedfordLouisville
MFR - SDF
MFRSDF
Medford
Fri 6/12
1:10 pm-10:59 pm
1 stop6h 49m
Louisville Intl
Mon 6/15
3:25 pm-9:16 pm
1 stop8h 51m
$698
MedfordLouisville
MFR - SDF
MFRSDF
Medford
Tue 6/23
1:10 pm-10:59 pm
1 stop6h 49m
Louisville Intl
Tue 6/30
3:25 pm-9:16 pm
1 stop8h 51m
$710
MedfordLouisville
MFR - SDF
MFRSDF
Medford
Thu 5/28
1:10 pm-10:59 pm
1 stop6h 49m
Louisville Intl
Mon 6/1
5:20 am-1:05 pm
2 stops10h 45m
$725
Cheapest one-way
MedfordLouisville
MFR - SDF
MFRSDF
Medford
Wed 7/15
6:00 am-7:13 pm
2 stops10h 13m
$315
Showing 1-10 of 12 resultsSorted by cheapest first
Compare providers for flights from Medford to Louisville
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Medford to Louisville in April.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Medford-Louisville flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Medford-Louisville flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Medford-Louisville flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Medford-Louisville flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Medford-Louisville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Medford to Louisville
Have a flexible travel schedule? Discover the best time to fly to Louisville from Medford with our price prediction graph.
MFR-SDF
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Reviews of airlines servicing Louisville
Get insights into the airlines that provide service to Louisville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Louisville. Reviews last updated April 27, 2026.
See what other customers who have flown with United Airlines from Medford to Louisville have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.1
Entertainment
7.1
Overall
7.4
Boarding
7.7
Food
6.6
Comfort
7.3
Reviews
1 / 20
8.0
ExcellentAnonymous,Apr 2026
DFW - EWR
Crew
8.1
Entertainment
7.1
Overall
7.4
Boarding
7.7
Food
6.6
Comfort
7.3
Reviews
1 / 20
8.0
ExcellentAnonymous,Apr 2026
DFW - EWR
Related info for your journey
Find useful and relevant information for your journey from Medford to Louisville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Louisville?
Book flights to Louisville if you plan to visit one of these locationsShepherdsville
Elizabethtown
Corydon
Jeffersonville
Bardstown
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Other flights to Louisville
Explore flights to Louisville departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on April 27, 2026.
Medford and Louisville flights
Browse other Medford and Louisville flight options. Last updated on April 27, 2026.
Other flights from Medford
Browse through other flights departing from Medford. Flights are based on user searches made on Cheapflights and were last updated on April 27, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top airline flying from Medford to Louisville
Discover the top airline that operate flights from Medford to Louisville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 27, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$329 | Average$482 | FlexibilityNo cancel fee | On-time69% |