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Santa Cruz de la Sierra

$292+ Cheap flights from Ohio to Santa Cruz de la Sierra (VVI)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/18. Fares are subject to change and may not be available on all flights or dates of travel.
CVG — VVI
Dec 23 — Dec 301
Tue 12/23
Tue 12/30
1 adult, Economy
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Find flight deals from Ohio to Santa Cruz de la Sierra

Cheapest flights from Ohio to Santa Cruz de la Sierra
Explore the most affordable flight options available from Ohio to Santa Cruz de la Sierra. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 23, 2025.

This Trip.com deal was found by Cheapflights users on 11/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/2411:37 amDTW - VVI
1 stop16h 13mMultiple Airlines
Wed 11/2611:35 pmVVI - DTW
1 stop15h 54mMultiple Airlines
Deal found 11/20$793
This Copa Airlines deal was found by Cheapflights users on 11/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/57:55 pmCLE - VVI
2 stops25h 51mCopa Airlines
Mon 12/1511:40 amVVI - CLE
2 stops23h 06mCopa Airlines
Deal found 11/23$1,271

Cheap flight deals from Ohio to Santa Cruz de la Sierra

Keep the following information in mind while searching for Ohio to Santa Cruz de la Sierra flight deals. Data was last updated November 23, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$734
(United Airlines)

One-way from

$292
(Avianca Connect)
Provider with most accurate pricing for Cleveland Hopkins Intl-Santa Cruz de la Sierra Viru Viru Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Cleveland Hopkins Intl-Santa Cruz de la Sierra Viru Viru Intl flights.
Search Deals
From Ohio to Santa Cruz de la Sierra Viru Viru Intl
Search Deals
One-way flight from Ohio to Santa Cruz de la Sierra Viru Viru Intl
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Ohio to Santa Cruz de la Sierra that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 23, 2025.
Use the filters below to find and compare flights from Ohio to Santa Cruz de la Sierra that are best for you.

Fly from

Ohio

Fly to

Santa Cruz de la Sierra

Route

Depart

Return

Price

CincinnatiSanta Cruz de la Sierra

CVG - VVI

CVGVVI

Cincinnati Cinci./N. Kentucky

Tue 1/13

6:25 am-10:50 pm

2 stops39h 25m

Santa Cruz de la Sierra Viru Viru Intl

Sat 1/24

11:44 am-10:49 am

2 stops24h 05m

$734

DetroitSanta Cruz de la Sierra

DTW - VVI

DTWVVI

Detroit Metropolitan Wayne County

Mon 1/26

7:15 am-10:50 pm

2 stops38h 35m

Santa Cruz de la Sierra Viru Viru Intl

Thu 1/29

11:44 am-10:10 pm

2 stops35h 26m

$837

DaytonSanta Cruz de la Sierra

DAY - VVI

DAYVVI

Dayton

Tue 4/28

2:44 pm-3:44 am

2 stops37h 00m

Santa Cruz de la Sierra Viru Viru Intl

Sat 5/2

11:44 am-9:47 am

2 stops22h 03m

$856

ClevelandSanta Cruz de la Sierra

CLE - VVI

CLEVVI

Cleveland Hopkins Intl

Sat 1/24

11:33 am-4:35 am

2 stops16h 02m

Santa Cruz de la Sierra Viru Viru Intl

Wed 1/28

7:26 am-10:43 am

2 stops28h 17m

$919

CincinnatiSanta Cruz de la Sierra

CVG - VVI

CVGVVI

Cincinnati Cinci./N. Kentucky

Sat 1/31

9:58 am-4:35 am

2 stops17h 37m

Santa Cruz de la Sierra Viru Viru Intl

Wed 2/4

7:26 am-5:09 pm

2 stops34h 43m

$949

ClevelandSanta Cruz de la Sierra

CLE - VVI

CLEVVI

Cleveland Hopkins Intl

Fri 3/6

7:00 am-4:50 am

1 stop20h 50m

Santa Cruz de la Sierra Viru Viru Intl

Sun 3/15

8:35 am-12:36 am

1 stop16h 01m

$964

ClevelandSanta Cruz de la Sierra

CLE - VVI

CLEVVI

Cleveland Hopkins Intl

Fri 3/6

7:05 am-3:38 am

2 stops19h 33m

Santa Cruz de la Sierra Viru Viru Intl

Sat 3/14

1:14 am-8:08 pm

2 stops18h 54m

$1,241

ClevelandSanta Cruz de la Sierra

CLE - VVI

CLEVVI

Cleveland Hopkins Intl

Fri 12/5

10:55 am-3:36 am

2 stops15h 41m

Santa Cruz de la Sierra Viru Viru Intl

Mon 12/15

11:40 am-9:46 am

2 stops23h 06m

$1,271

CincinnatiSanta Cruz de la Sierra

CVG - VVI

CVGVVI

Cincinnati Cinci./N. Kentucky

Tue 1/13

10:05 am-2:35 am

2 stops39h 30m

Santa Cruz de la Sierra Viru Viru Intl

Fri 1/23

3:40 am-7:03 pm

2 stops16h 23m

$1,312

DetroitSanta Cruz de la Sierra

DTW - VVI

DTWVVI

Detroit Metropolitan Wayne County

Mon 1/26

11:05 am-3:44 am

2 stops15h 39m

Santa Cruz de la Sierra Viru Viru Intl

Wed 1/28

1:15 am-6:59 pm

2 stops18h 44m

$1,317

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/23

Showing 1-10 of 16 results
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Best time to book a flight from Ohio to Santa Cruz de la Sierra

Have a flexible travel schedule? Discover the best time to fly to Santa Cruz de la Sierra from Ohio with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Ohio to Santa Cruz de la Sierra
No data available for this route at this time. Please check back soon.

Related info for your journey

Find useful and relevant information for your journey from Ohio to Santa Cruz de la Sierra. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Santa Cruz de la Sierra from Ohio?

    For a flight from Ohio to Santa Cruz de la Sierra, you will be flying into Viru Viru Intl. Santa Cruz de la Sierra Viru Viru Intl (VVI) is just 11.5 mi from the center of the city.

  • How long is the flight from Ohio to Santa Cruz de la Sierra?

    Airlines like United Airlines, LATAM Airlines, and Copa Airlines fly from Ohio to Santa Cruz de la Sierra in about 16h 02m. The time it takes to get you to your destination can typically vary by up to 23h 23m. Airlines will cover a distance of 4250 mi. This flight may include one or multiple stops.

  • What are the most popular routes from Ohio to Santa Cruz de la Sierra?

    The most popular route from Ohio to Santa Cruz de la Sierra is Cleveland Hopkins Intl - Santa Cruz de la Sierra Viru Viru Intl. You may also consider Detroit Metropolitan Wayne County - Santa Cruz de la Sierra Viru Viru Intl or Cincinnati Cinci./N. Kentucky - Santa Cruz de la Sierra Viru Viru Intl.

  • Can I find deals for flights from Ohio to Santa Cruz de la Sierra that include hotel bookings?

    Yes. In addition to deals on Ohio to Santa Cruz de la Sierra flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Ohio to Santa Cruz de la Sierra?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Ohio to Santa Cruz de la Sierra.

  • Can I find deals for business class flights from Ohio to Santa Cruz de la Sierra?

    Yes. Cheapflights offers flight deals from Ohio to Santa Cruz de la Sierra by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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Alternative routes for Ohio to Santa Cruz de la Sierra

See prices for flight routes from nearby airports that may be better suited for you.
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