Santa Cruz de la Sierra

$373+ Cheap flights from Ohio to Santa Cruz de la Sierra (VVI)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/13. Fares are subject to change and may not be available on all flights or dates of travel.
CVG — VVI
Aug 22 — Aug 291
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Cheap flight deals from Ohio to Santa Cruz de la Sierra

Keep the following information in mind while searching for Ohio to Santa Cruz de la Sierra flight deals. Data was last updated August 17, 2025.

Round-trip from

$1,043
(Copa Airlines)

One-way from

$373
(United)
From Ohio to Santa Cruz de la Sierra Viru Viru Intl
One-way flight from Ohio to Santa Cruz de la Sierra Viru Viru Intl

Find flight deals from Ohio to Santa Cruz de la Sierra

Cheapest flights from Ohio to Santa Cruz de la Sierra
Explore the most affordable flight options available from Ohio to Santa Cruz de la Sierra. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 17, 2025.

This Copa Airlines deal was found by Cheapflights users on 8/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/2210:55 amCLE - VVI
2 stops15h 41mCopa Airlines
Tue 12/3011:40 amVVI - CLE
2 stops23h 00mCopa Airlines
Deal found 8/15$1,043
This Avianca Connect deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca Connect is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/227:00 amDTW - VVI
2 stops18h 35mMultiple Airlines
Sun 12/283:40 amVVI - DTW
2 stops18h 43mMultiple Airlines
Deal found 8/16$1,062
This Copa Airlines deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/2210:55 amCLE - VVI
2 stops15h 41mCopa Airlines
Mon 12/2911:40 amVVI - CLE
2 stops23h 00mCopa Airlines
Deal found 8/16$1,116
This Kiwi.com deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/225:41 pmCLE - VVI
1 stop34h 09mMultiple Airlines
Mon 12/2911:35 pmVVI - CLE
1 stop26h 13mMultiple Airlines
Deal found 8/16$1,502
This Copa Airlines deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/298:43 amCLE - VVI
2 stops17h 53mCopa Airlines
Sat 1/31:15 amVVI - CLE
2 stops19h 56mCopa Airlines
Deal found 8/16$1,514
This Copa Airlines deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/227:49 pmDTW - VVI
2 stops25h 57mCopa Airlines
Mon 12/2911:40 amVVI - DTW
2 stops23h 26mCopa Airlines
Deal found 8/16$1,669
This Kiwi.com deal was found by Cheapflights users on 8/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/225:41 pmCLE - VVI
1 stop34h 09mMultiple Airlines
Tue 12/305:25 amVVI - CLE
2 stops20h 23mMultiple Airlines
Deal found 8/15$1,879
This Kiwi.com deal was found by Cheapflights users on 8/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/295:41 pmCLE - VVI
1 stop34h 09mMultiple Airlines
Sun 1/45:25 amVVI - CLE
2 stops20h 23mMultiple Airlines
Deal found 8/15$2,004
This Avianca deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/310:25 amDAY - VVI
2 stops15h 25mAvianca
Mon 10/62:50 amVVI - DAY
2 stops16h 09mAvianca
Deal found 8/14$2,066
This SmartFares deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure SmartFares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/294:46 pmCLE - VVI
2 stops34h 49mLATAM Airlines
Sun 1/45:25 amVVI - CLE
2 stops31h 03mLATAM Airlines
Deal found 8/16$2,883

Cheapflights Fare Finder

 
Customize your flight search to find flights from Ohio to Santa Cruz de la Sierra that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 17, 2025.
Use the filters below to find and compare flights from Ohio to Santa Cruz de la Sierra that are best for you.

Fly from

Ohio

Fly to

Santa Cruz de la Sierra

Route

Depart

Return

Price

ClevelandSanta Cruz de la Sierra

CLE - VVI

CLEVVI

Cleveland Hopkins Intl

Mon 12/22

10:55 am-3:36 am

2 stops15h 41m

Santa Cruz de la Sierra Viru Viru Intl

Tue 12/30

11:40 am-9:40 am

2 stops23h 00m

$1,043

DetroitSanta Cruz de la Sierra

DTW - VVI

DTWVVI

Detroit Metropolitan Wayne County

Mon 12/22

7:00 am-2:35 am

2 stops18h 35m

Santa Cruz de la Sierra Viru Viru Intl

Sun 12/28

3:40 am-9:23 pm

2 stops18h 43m

$1,062

ClevelandSanta Cruz de la Sierra

CLE - VVI

CLEVVI

Cleveland Hopkins Intl

Mon 12/22

10:55 am-3:36 am

2 stops15h 41m

Santa Cruz de la Sierra Viru Viru Intl

Sun 12/28

1:09 am-8:11 pm

2 stops20h 02m

$1,116

ClevelandSanta Cruz de la Sierra

CLE - VVI

CLEVVI

Cleveland Hopkins Intl

Mon 12/22

5:41 pm-4:50 am

1 stop34h 09m

Santa Cruz de la Sierra Viru Viru Intl

Mon 12/29

11:35 pm-12:48 am

1 stop26h 13m

$1,502

ClevelandSanta Cruz de la Sierra

CLE - VVI

CLEVVI

Cleveland Hopkins Intl

Mon 12/29

8:43 am-3:36 am

2 stops17h 53m

Santa Cruz de la Sierra Viru Viru Intl

Sat 1/3

1:15 am-8:11 pm

2 stops19h 56m

$1,514

DetroitSanta Cruz de la Sierra

DTW - VVI

DTWVVI

Detroit Metropolitan Wayne County

Mon 12/22

7:49 pm-10:46 pm

2 stops25h 57m

Santa Cruz de la Sierra Viru Viru Intl

Mon 12/29

11:40 am-10:06 am

2 stops23h 26m

$1,669

ClevelandSanta Cruz de la Sierra

CLE - VVI

CLEVVI

Cleveland Hopkins Intl

Mon 12/22

5:41 pm-4:50 am

1 stop34h 09m

Santa Cruz de la Sierra Viru Viru Intl

Tue 12/30

5:25 am-12:48 am

2 stops20h 23m

$1,879

ClevelandSanta Cruz de la Sierra

CLE - VVI

CLEVVI

Cleveland Hopkins Intl

Mon 12/29

5:41 pm-4:50 am

1 stop34h 09m

Santa Cruz de la Sierra Viru Viru Intl

Sun 1/4

5:25 am-12:48 am

2 stops20h 23m

$2,004

DaytonSanta Cruz de la Sierra

DAY - VVI

DAYVVI

Dayton

Fri 10/3

10:25 am-1:50 am

2 stops15h 25m

Santa Cruz de la Sierra Viru Viru Intl

Mon 10/6

2:50 am-6:59 pm

2 stops16h 09m

$2,066

ClevelandSanta Cruz de la Sierra

CLE - VVI

CLEVVI

Cleveland Hopkins Intl

Mon 12/29

4:46 pm-4:35 am

2 stops34h 49m

Santa Cruz de la Sierra Viru Viru Intl

Sun 1/4

5:25 am-11:28 am

2 stops31h 03m

$2,883

Flights are sorted by cheapest round-trip flights first.

Deals found on 8/16

Showing 1-10 of 11 results
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Best time to book a flight from Ohio to Santa Cruz de la Sierra

Have a flexible travel schedule? Discover the best time to fly to Santa Cruz de la Sierra from Ohio with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Ohio to Santa Cruz de la Sierra
No data available for this route at this time. Please check back soon.

Related info for your journey

Find useful and relevant information for your journey from Ohio to Santa Cruz de la Sierra. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • What airport do you fly into for flights to Santa Cruz de la Sierra from Ohio?

    For a flight from Ohio to Santa Cruz de la Sierra, you will be flying into Viru Viru Intl. Santa Cruz de la Sierra Viru Viru Intl (VVI) is just 11.5 mi from the center of the city.

  • What are the most popular routes from Ohio to Santa Cruz de la Sierra?

  • Can I find deals for flights from Ohio to Santa Cruz de la Sierra that include hotel bookings?

    Yes. In addition to deals on Ohio to Santa Cruz de la Sierra flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Ohio to Santa Cruz de la Sierra?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Ohio to Santa Cruz de la Sierra.

  • Can I find deals for business class flights from Ohio to Santa Cruz de la Sierra?

    Yes. Cheapflights offers flight deals from Ohio to Santa Cruz de la Sierra by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Ohio to Santa Cruz de la Sierra?

    Currently, October is the cheapest month in which you can book a flight from Ohio to Santa Cruz de la Sierra (average of $597). Flying from Ohio to Santa Cruz de la Sierra in December is currently the most expensive (average of $822). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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