How long is the flight from North Carolina to Santa Cruz de la Sierra?

A quick flight from North Carolina to Santa Cruz de la Sierra can take about 21h 25m. United Airlines provides one of the quickest options available for as low as $603. The distance from North Carolina to Santa Cruz de la Sierra is about 3835 mi.

What is the cheapest time of day to fly from NC to VVI?

When flying from North Carolina to Santa Cruz de la Sierra, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

What airport do you fly into for flights to Santa Cruz de la Sierra from North Carolina?

Located just 11.5 mi from the city center, Santa Cruz de la Sierra Viru Viru Intl (VVI) is the airport most travelers will use when flying to Santa Cruz de la Sierra from North Carolina.

How can I find direct flights from North Carolina to Santa Cruz de la Sierra?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from North Carolina to Santa Cruz de la Sierra.

Can I find deals for business class flights from North Carolina to Santa Cruz de la Sierra?

Yes. Cheapflights offers flight deals from North Carolina to Santa Cruz de la Sierra by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$603+ Flights from North Carolina to Santa Cruz de la Sierra

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Cheap flight deals from North Carolina to Santa Cruz de la Sierra

Cheapest flights from North Carolina to Santa Cruz de la Sierra
Explore the most affordable flight options available from North Carolina to Santa Cruz de la Sierra. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 29, 2026.

Wed 3/258:22 am

RDU

VVI

2 stops38h 28m

United Airlines

Thu 4/211:48 am

VVI

RDU

2 stops21h 44m

United Airlines

Deal found 1/27

$603

Wed 9/24:21 pm

RDU

VVI

1 stop11h 17m

Copa Airlines

Tue 9/221:12 am

VVI

RDU

1 stop13h 16m

Copa Airlines

Deal found 1/27

$610

Mon 2/236:15 am

RDU

VVI

2 stops15h 35m

United Airlines

Thu 2/2611:44 am

VVI

RDU

2 stops35h 49m

United Airlines

Deal found 1/26

$658

Wed 3/256:13 am

RDU

VVI

2 stops21h 25m

Copa Airlines

Tue 4/281:15 am

VVI

RDU

2 stops20h 33m

Copa Airlines

Deal found 1/27

$665

Sat 3/1410:40 am

RDU

VVI

2 stops40h 51m

United Airlines

Sat 3/2111:54 am

VVI

RDU

2 stops50h 10m

United Airlines

Deal found 1/28

$670

Wed 3/256:23 am

CLT

VVI

2 stops40h 27m

United Airlines

Tue 4/711:48 am

VVI

CLT

2 stops33h 53m

United Airlines

Deal found 1/27

$683

Sun 3/296:00 am

CLT

VVI

2 stops45h 36m

United Airlines

Tue 4/711:48 am

VVI

CLT

2 stops22h 40m

United Airlines

Deal found 1/27

$689

Fri 3/276:23 am

CLT

VVI

2 stops40h 27m

United Airlines

Tue 4/711:48 am

VVI

CLT

2 stops22h 40m

United Airlines

Deal found 1/27

$693

Wed 9/211:20 am

RDU

VVI

2 stops23h 50m

Multiple Airlines

Tue 9/221:12 am

VVI

RDU

2 stops20h 43m

Multiple Airlines

Deal found 1/26

$697

Fri 3/276:23 am

CLT

VVI

2 stops40h 27m

United Airlines

Thu 4/211:48 am

VVI

CLT

2 stops22h 05m

United Airlines

Deal found 1/27

$703

Mon 3/306:00 am

CLT

VVI

2 stops16h 50m

United Airlines

Thu 4/211:48 am

VVI

CLT

2 stops22h 05m

United Airlines

Deal found 1/27

$723

Wed 3/2511:28 am

CLT

VVI

2 stops16h 10m

United Airlines

Sat 4/411:48 am

VVI

CLT

2 stops22h 05m

United Airlines

Deal found 1/27

$728

Best flights from North Carolina to Santa Cruz de la Sierra
Discover carefully curated flight deals from North Carolina to Santa Cruz de la Sierra that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated January 29, 2026.

Wed 3/256:13 am

RDU

VVI

2 stops21h 25m

United Airlines

Tue 4/711:48 am

VVI

RDU

2 stops34h 00m

United Airlines

Deal found 1/27

$603

Sat 3/2810:40 am

RDU

VVI

2 stops36h 10m

United Airlines

Tue 4/711:48 am

VVI

RDU

2 stops34h 39m

United Airlines

Deal found 1/27

$603

Wed 3/2510:22 am

RDU

VVI

2 stops17h 16m

United Airlines

Mon 4/611:48 am

VVI

RDU

3 stops50h 10m

United Airlines

Deal found 1/27

$603

Sat 3/2810:40 am

RDU

VVI

2 stops36h 10m

United Airlines

Mon 4/611:48 am

VVI

RDU

3 stops50h 10m

United Airlines

Deal found 1/27

$603

Mon 3/307:50 pm

RDU

VVI

2 stops27h 00m

United Airlines

Mon 4/611:48 am

VVI

RDU

3 stops50h 10m

United Airlines

Deal found 1/27

$603

Thu 3/266:15 am

RDU

VVI

2 stops40h 35m

United Airlines

Thu 4/211:48 am

VVI

RDU

2 stops35h 56m

United Airlines

Deal found 1/27

$603

Thu 3/266:00 am

RDU

VVI

2 stops40h 50m

United Airlines

Tue 4/711:48 am

VVI

RDU

2 stops33h 35m

United Airlines

Deal found 1/27

$603

Mon 3/307:50 pm

RDU

VVI

2 stops27h 00m

United Airlines

Thu 4/211:48 am

VVI

RDU

2 stops35h 56m

United Airlines

Deal found 1/27

$603

Mon 3/3010:38 am

RDU

VVI

2 stops36h 12m

United Airlines

Tue 4/711:48 am

VVI

RDU

2 stops33h 35m

United Airlines

Deal found 1/27

$603

Sun 3/2910:38 am

RDU

VVI

2 stops16h 58m

United Airlines

Thu 4/211:48 am

VVI

RDU

2 stops22h 18m

United Airlines

Deal found 1/27

$603

Mon 3/306:00 am

CLT

VVI

2 stops21h 36m

United Airlines

Mon 4/611:48 am

VVI

CLT

2 stops26h 17m

United Airlines

Deal found 1/27

$683

Mon 5/46:35 am

CLT

VVI

2 stops20h 56m

United Airlines

Mon 5/2511:47 am

VVI

CLT

2 stops26h 17m

United Airlines

Deal found 1/27

$683

Tue 5/57:43 pm

CLT

VVI

2 stops31h 48m

United Airlines

Tue 5/2611:47 am

VVI

CLT

2 stops26h 17m

United Airlines

Deal found 1/27

$683

Mon 5/46:35 am

CLT

VVI

2 stops20h 56m

United Airlines

Tue 5/2611:47 am

VVI

CLT

2 stops34h 05m

United Airlines

Deal found 1/27

$683

Tue 3/316:15 am

CLT

VVI

2 stops40h 27m

United Airlines

Tue 4/711:48 am

VVI

CLT

2 stops33h 27m

United Airlines

Deal found 1/27

$683

Thu 3/266:15 am

CLT

VVI

2 stops40h 35m

United Airlines

Tue 4/711:48 am

VVI

CLT

2 stops33h 15m

United Airlines

Deal found 1/27

$683

Tue 5/56:35 am

CLT

VVI

2 stops40h 03m

United Airlines

Mon 5/2511:47 am

VVI

CLT

2 stops26h 17m

United Airlines

Deal found 1/27

$683

Thu 3/269:40 am

CLT

VVI

2 stops37h 10m

United Airlines

Thu 4/211:48 am

VVI

CLT

2 stops22h 40m

United Airlines

Deal found 1/27

$683

Sun 3/296:00 am

CLT

VVI

2 stops45h 36m

United Airlines

Mon 4/611:48 am

VVI

CLT

2 stops33h 53m

United Airlines

Deal found 1/27

$689

Fri 3/276:23 am

CLT

VVI

2 stops40h 27m

United Airlines

Tue 4/711:48 am

VVI

CLT

2 stops22h 40m

United Airlines

Deal found 1/27

$693

Fri 3/276:23 am

CLT

VVI

2 stops40h 27m

United Airlines

Mon 4/611:48 am

VVI

CLT

2 stops33h 53m

United Airlines

Deal found 1/27

$693

Sat 3/289:40 am

CLT

VVI

2 stops37h 10m

United Airlines

Tue 4/711:48 am

VVI

CLT

2 stops33h 53m

United Airlines

Deal found 1/27

$693

Last-minute flights from North Carolina to Santa Cruz de la Sierra
Discover last-minute flight deals from North Carolina to Santa Cruz de la Sierra. Data last updated January 29, 2026 and is based on user searches.

Thu 2/197:44 pm

CLT

VVI

2 stops31h 00m

United Airlines

Thu 2/2611:44 am

VVI

CLT

2 stops24h 03m

United Airlines

Deal found 1/28

$3,353

Fri 2/207:44 pm

CLT

VVI

2 stops26h 06m

Copa Airlines

Thu 2/261:15 am

VVI

CLT

2 stops18h 40m

Copa Airlines

Deal found 1/28

$4,130

Sun 2/226:15 am

CLT

VVI

2 stops44h 29m

United Airlines

Thu 2/2611:44 am

VVI

CLT

2 stops24h 03m

United Airlines

Deal found 1/28

$851

Mon 2/236:15 am

RDU

VVI

2 stops15h 35m

United Airlines

Thu 2/2611:44 am

VVI

RDU

2 stops35h 49m

United Airlines

Deal found 1/26

$658

Mon 2/233:08 pm

RDU

VVI

3 stops34h 27m

Multiple Airlines

Wed 2/253:40 am

VVI

RDU

3 stops35h 33m

Multiple Airlines

Deal found 1/29

$1,138

Find flight deals from North Carolina to Santa Cruz de la Sierra

Most accurate provider	FlightHub 3 stars
Most trusted provider	FlightHub 3 stars
Round-trip from	$603 (United Airlines)

Provider with most accurate pricing for Raleigh-Durham-Santa Cruz de la Sierra Viru Viru Intl flight deals.

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Provider most trusted by Cheapflights users for Raleigh-Durham-Santa Cruz de la Sierra Viru Viru Intl flights.

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From North Carolina to Santa Cruz de la Sierra Viru Viru Intl

Search Deals

Cheapflights Fare Finder

Use the filters below to find and compare flights from North Carolina to Santa Cruz de la Sierra that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

RaleighSanta Cruz de la Sierra

RDU - VVI

RDUVVI

Raleigh-Durham

Wed 3/25

6:13 am-3:38 am

2 stops21h 25m

Santa Cruz de la Sierra Viru Viru Intl

Tue 4/7

11:48 am-9:48 pm

2 stops34h 00m

$603

RaleighSanta Cruz de la Sierra

RDU - VVI

RDUVVI

Raleigh-Durham

Sat 3/28

10:40 am-10:50 pm

2 stops36h 10m

Santa Cruz de la Sierra Viru Viru Intl

Tue 4/7

11:48 am-10:27 pm

2 stops34h 39m

$603

RaleighSanta Cruz de la Sierra

RDU - VVI

RDUVVI

Raleigh-Durham

Wed 3/25

10:22 am-3:38 am

2 stops17h 16m

Santa Cruz de la Sierra Viru Viru Intl

Mon 4/6

11:48 am-1:58 pm

3 stops50h 10m

$603

RaleighSanta Cruz de la Sierra

RDU - VVI

RDUVVI

Raleigh-Durham

Sat 3/28

10:40 am-10:50 pm

2 stops36h 10m

Santa Cruz de la Sierra Viru Viru Intl

Mon 4/6

11:48 am-1:58 pm

3 stops50h 10m

$603

RaleighSanta Cruz de la Sierra

RDU - VVI

RDUVVI

Raleigh-Durham

Mon 3/30

7:50 pm-10:50 pm

2 stops27h 00m

Santa Cruz de la Sierra Viru Viru Intl

Mon 4/6

11:48 am-1:58 pm

3 stops50h 10m

$603

RaleighSanta Cruz de la Sierra

RDU - VVI

RDUVVI

Raleigh-Durham

Thu 3/26

6:15 am-10:50 pm

2 stops40h 35m

Santa Cruz de la Sierra Viru Viru Intl

Thu 4/2

11:48 am-11:44 pm

2 stops35h 56m

$603

RaleighSanta Cruz de la Sierra

RDU - VVI

RDUVVI

Raleigh-Durham

Thu 3/26

6:00 am-10:50 pm

2 stops40h 50m

Santa Cruz de la Sierra Viru Viru Intl

Tue 4/7

11:48 am-9:23 pm

2 stops33h 35m

$603

RaleighSanta Cruz de la Sierra

RDU - VVI

RDUVVI

Raleigh-Durham

Mon 3/30

7:50 pm-10:50 pm

2 stops27h 00m

Santa Cruz de la Sierra Viru Viru Intl

Thu 4/2

11:48 am-11:44 pm

2 stops35h 56m

$603

RaleighSanta Cruz de la Sierra

RDU - VVI

RDUVVI

Raleigh-Durham

Mon 3/30

10:38 am-10:50 pm

2 stops36h 12m

Santa Cruz de la Sierra Viru Viru Intl

Tue 4/7

11:48 am-9:23 pm

2 stops33h 35m

$603

RaleighSanta Cruz de la Sierra

RDU - VVI

RDUVVI

Raleigh-Durham

Sun 3/29

10:38 am-3:36 am

2 stops16h 58m

Santa Cruz de la Sierra Viru Viru Intl

Thu 4/2

11:48 am-10:06 am

2 stops22h 18m

$603

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/27

Showing 1-10 of 22 results

Best time to book a flight from North Carolina to Santa Cruz de la Sierra

Have a flexible travel schedule? Discover the best time to fly to Santa Cruz de la Sierra from North Carolina with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from North Carolina to Santa Cruz de la Sierra

No data available for this route at this time. Please check back soon.

Related info for your journey

What airport do you fly into for flights to Santa Cruz de la Sierra from North Carolina?
Located just 11.5 mi from the city center, Santa Cruz de la Sierra Viru Viru Intl (VVI) is the airport most travelers will use when flying to Santa Cruz de la Sierra from North Carolina.
How long is the flight from North Carolina to Santa Cruz de la Sierra?
A quick flight from North Carolina to Santa Cruz de la Sierra can take about 21h 25m. United Airlines provides one of the quickest options available for as low as $603. The distance from North Carolina to Santa Cruz de la Sierra is about 3835 mi.
Can I find deals for flights from North Carolina to Santa Cruz de la Sierra that include hotel bookings?
Yes. In addition to deals on North Carolina to Santa Cruz de la Sierra flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from North Carolina to Santa Cruz de la Sierra?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from North Carolina to Santa Cruz de la Sierra.
Can I find deals for business class flights from North Carolina to Santa Cruz de la Sierra?
Yes. Cheapflights offers flight deals from North Carolina to Santa Cruz de la Sierra by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Alternative routes for North Carolina to Santa Cruz de la Sierra

Dulles Intl to Santa Cruz de la Sierra flights

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Reagan-National to Santa Cruz de la Sierra flights

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Dulles Intl to La Paz flights

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Reagan-National to La Paz flights

LaGuardia to Santa Cruz de la Sierra flights

Boston to Santa Cruz de la Sierra flights

Newark to La Paz flights

San Francisco to La Paz flights

Reagan-National to Cochabamba flights

Dulles Intl to Cochabamba flights

O'Hare Intl to Santa Cruz de la Sierra flights

Hobby to Santa Cruz de la Sierra flights

LaGuardia to La Paz flights

Baltimore to Cochabamba flights

George Bush Intcntl to Santa Cruz de la Sierra flights

Baltimore to La Paz flights

O'Hare Intl to La Paz flights

Boston to La Paz flights

Hobby to La Paz flights

George Bush Intcntl to La Paz flights

Orlando to Santa Cruz de la Sierra flights

Charlotte to Santa Cruz de la Sierra flights

Fort Lauderdale to La Paz flights

Orlando to La Paz flights

Portland to La Paz flights

Atlanta to La Paz flights

Dallas/Fort Worth to Santa Cruz de la Sierra flights

Ontario to Santa Cruz de la Sierra flights

Tampa to Santa Cruz de la Sierra flights

Denver to Santa Cruz de la Sierra flights

Las Vegas to Santa Cruz de la Sierra flights

Portland to Santa Cruz de la Sierra flights

Sky Harbor Intl to Santa Cruz de la Sierra flights

St. Louis to Santa Cruz de la Sierra flights

Dallas/Fort Worth to La Paz flights

Indianapolis to Santa Cruz de la Sierra flights

Raleigh to Santa Cruz de la Sierra flights

Top airline flying from North Carolina to Santa Cruz de la Sierra

Airline	Cheapest	Average	Flexibility	On-time
Copa Airlines	Cheapest$411	Average$598	FlexibilityNo cancel fee	On-time70%

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$603+ Cheap flights from North Carolina to Santa Cruz de la Sierra (VVI)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/25. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from North Carolina to Santa Cruz de la Sierra with Cheapflights

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Cheap flight deals from North Carolina to Santa Cruz de la Sierra

Cheapest flights from North Carolina to Santa Cruz de la SierraExplore the most affordable flight options available from North Carolina to Santa Cruz de la Sierra. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 29, 2026.

Explore the most affordable flight options available from North Carolina to Santa Cruz de la Sierra. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 29, 2026.

Find flight deals from North Carolina to Santa Cruz de la Sierra

Keep the following information in mind while searching for North Carolina to Santa Cruz de la Sierra flight deals. Data was last updated January 29, 2026.

Most accurate provider

Most trusted provider

Round-trip from

Cheapflights Fare Finder

Use the filters below to find and compare flights from North Carolina to Santa Cruz de la Sierra that are best for you.

Best time to book a flight from North Carolina to Santa Cruz de la Sierra

Have a flexible travel schedule? Discover the best time to fly to Santa Cruz de la Sierra from North Carolina with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from North Carolina to Santa Cruz de la Sierra

Related info for your journey

Find useful and relevant information for your journey from North Carolina to Santa Cruz de la Sierra. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What airport do you fly into for flights to Santa Cruz de la Sierra from North Carolina?

How long is the flight from North Carolina to Santa Cruz de la Sierra?

Can I find deals for flights from North Carolina to Santa Cruz de la Sierra that include hotel bookings?

How can I find direct flights from North Carolina to Santa Cruz de la Sierra?

Can I find deals for business class flights from North Carolina to Santa Cruz de la Sierra?

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for North Carolina to Santa Cruz de la Sierra

See prices for flight routes from nearby airports that may be better suited for you.

Top airline flying from North Carolina to Santa Cruz de la Sierra

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Book with Flexibility

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Cheapest flights from North Carolina to Santa Cruz de la Sierra
Explore the most affordable flight options available from North Carolina to Santa Cruz de la Sierra. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 29, 2026.