HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Santa Cruz de la Sierra

$313+ Cheap flights from North Carolina to Santa Cruz de la Sierra (VVI)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/13. Fares are subject to change and may not be available on all flights or dates of travel.
RDU — VVI
Jul 5 — Jul 121
Sat 7/5
Sat 7/12
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from North Carolina to Santa Cruz de la Sierra with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from North Carolina to Santa Cruz de la Sierra

Keep the following information in mind while searching for North Carolina to Santa Cruz de la Sierra flight deals. Data was last updated June 30, 2025.

Round-trip from

$611
(United Airlines)

One-way from

$313
(United Airlines)
From North Carolina to Santa Cruz de la Sierra Viru Viru Intl
Search Deals
One-way flight from North Carolina to Santa Cruz de la Sierra Viru Viru Intl
Search Deals

Find flight deals from North Carolina to Santa Cruz de la Sierra

Cheapest flights from North Carolina to Santa Cruz de la Sierra
Explore the most affordable flight options available from North Carolina to Santa Cruz de la Sierra. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 30, 2025.

This Copa Airlines deal was found by Cheapflights users on 6/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/14:19 pmRDU - VVI
1 stop11h 19mCopa Airlines
Sat 10/41:09 amVVI - RDU
1 stop13h 19mCopa Airlines
Deal found 6/29$539
This United Airlines deal was found by Cheapflights users on 6/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/136:49 amRDU - VVI
2 stops39h 30mUnited Airlines
Tue 8/191:09 amVVI - RDU
2 stops20h 43mUnited Airlines
Deal found 6/29$611
This Mytrip deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/148:59 amRDU - VVI
3 stops19h 36mMultiple Airlines
Wed 8/202:55 amVVI - RDU
3 stops29h 37mMultiple Airlines
Deal found 6/30$1,010
This SmartFares deal was found by Cheapflights users on 6/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure SmartFares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/18:20 amRDU - VVI
2 stops20h 15mLATAM Airlines
Sun 10/510:13 amVVI - RDU
2 stops28h 08mLATAM Airlines
Deal found 6/29$1,528
This Mytrip deal was found by Cheapflights users on 6/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/25:45 amCLT - VVI
3 stops20h 05mMultiple Airlines
Thu 7/32:55 amVVI - CLT
3 stops29h 11mMultiple Airlines
Deal found 6/28$1,584
This FlightHub deal was found by Cheapflights users on 6/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/26:00 amCLT - VVI
2 stops19h 50mAvianca
Thu 7/32:55 amVVI - CLT
2 stops30h 52mAvianca
Deal found 6/28$1,797
This SmartFares deal was found by Cheapflights users on 6/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure SmartFares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/26:52 amCLT - VVI
2 stops21h 43mLATAM Airlines
Fri 7/45:20 amVVI - CLT
2 stops18h 39mLATAM Airlines
Deal found 6/28$2,158

Cheapflights Fare Finder

Customize your flight search to find flights from North Carolina to Santa Cruz de la Sierra that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 30, 2025.
Use the filters below to find and compare flights from North Carolina to Santa Cruz de la Sierra that are best for you.

Fly from

North Carolina

Fly to

Santa Cruz de la Sierra

Route

Depart

Return

Price

RaleighSanta Cruz de la Sierra

RDU - VVI

RDUVVI

Raleigh-Durham

Wed 8/13

6:49 am-10:19 pm

2 stops39h 30m

Santa Cruz de la Sierra Viru Viru Intl

Tue 8/19

1:09 am-9:52 pm

2 stops20h 43m

$611

RaleighSanta Cruz de la Sierra

RDU - VVI

RDUVVI

Raleigh-Durham

Thu 8/14

10:34 am-3:37 am

2 stops41h 03m

Santa Cruz de la Sierra Viru Viru Intl

Thu 8/21

12:15 pm-2:27 pm

1 stop26h 12m

$708

RaleighSanta Cruz de la Sierra

RDU - VVI

RDUVVI

Raleigh-Durham

Thu 8/14

8:59 am-4:35 am

3 stops19h 36m

Santa Cruz de la Sierra Viru Viru Intl

Wed 8/20

2:55 am-8:32 am

3 stops29h 37m

$1,010

RaleighSanta Cruz de la Sierra

RDU - VVI

RDUVVI

Raleigh-Durham

Tue 8/12

6:30 am-4:35 am

3 stops22h 05m

Santa Cruz de la Sierra Viru Viru Intl

Tue 8/19

5:20 am-8:52 am

3 stops27h 32m

$1,968

RaleighSanta Cruz de la Sierra

RDU - VVI

RDUVVI

Raleigh-Durham

Wed 8/13

6:49 am-10:19 pm

2 stops15h 30m

$313

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/28

Best time to book a flight from North Carolina to Santa Cruz de la Sierra

Have a flexible travel schedule? Discover the best time to fly to Santa Cruz de la Sierra from North Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from North Carolina to Santa Cruz de la Sierra

What is the cheapest time of day to fly from NC to VVI?

Find hourly flight availability from North Carolina to Santa Cruz de la Sierra. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated June 30, 2025.

When flying from North Carolina to Santa Cruz de la Sierra, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Reviews of airlines servicing Santa Cruz de la Sierra

Get insights into the airlines that provide service to Santa Cruz de la Sierra. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santa Cruz de la Sierra. Reviews last updated June 30, 2025.
See what other customers who have flown with LATAM Airlines, Copa Airlines, and United Airlines from North Carolina to Santa Cruz de la Sierra have to say. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
LATAM Airlines
7.5
Good
1,801 reviews

Overall

7.5

Entertainment

7.0

Comfort

7.4

Food

6.7

Crew

8.1

Boarding

7.6

Reviews

1 / 20
4.0
Okay

Murilo,Jun 2025

SFO - LAX

I had mixed feelings regarding this flight. Called several times Latam and Delta regarding the purchase of checked baggage and price. I was told 80 dollars, could not buy it ahead of time,, they told me it was not Possible, that I had to buy at the airport. Check in my luggage the attendant says 80 dollars but I was charged 200 . No one could get me a solid answer why. Very disappointing
LATAM Airlines
7.5
Good
1,801 reviews
LATAM Airlines
7.5
Good
1,801 reviews

Overall

7.5

Entertainment

7.0

Comfort

7.4

Food

6.7

Crew

8.1

Boarding

7.6

Reviews

1 / 20
4.0
Okay

Murilo,Jun 2025

SFO - LAX

I had mixed feelings regarding this flight. Called several times Latam and Delta regarding the purchase of checked baggage and price. I was told 80 dollars, could not buy it ahead of time,, they told me it was not Possible, that I had to buy at the airport. Check in my luggage the attendant says 80 dollars but I was charged 200 . No one could get me a solid answer why. Very disappointing
Copa Airlines
7.5
Good
1,465 reviews
LATAM Airlines
7.5
Good
1,801 reviews

Overall

7.5

Entertainment

7.0

Comfort

7.4

Food

6.7

Crew

8.1

Boarding

7.6

Reviews

1 / 20
4.0
Okay

Murilo,Jun 2025

SFO - LAX

I had mixed feelings regarding this flight. Called several times Latam and Delta regarding the purchase of checked baggage and price. I was told 80 dollars, could not buy it ahead of time,, they told me it was not Possible, that I had to buy at the airport. Check in my luggage the attendant says 80 dollars but I was charged 200 . No one could get me a solid answer why. Very disappointing
United Airlines
7.4
Good
8,852 reviews
LATAM Airlines
7.5
Good
1,801 reviews

Overall

7.5

Entertainment

7.0

Comfort

7.4

Food

6.7

Crew

8.1

Boarding

7.6

Reviews

1 / 20
4.0
Okay

Murilo,Jun 2025

SFO - LAX

I had mixed feelings regarding this flight. Called several times Latam and Delta regarding the purchase of checked baggage and price. I was told 80 dollars, could not buy it ahead of time,, they told me it was not Possible, that I had to buy at the airport. Check in my luggage the attendant says 80 dollars but I was charged 200 . No one could get me a solid answer why. Very disappointing

Related info for your journey

Find useful and relevant information for your journey from North Carolina to Santa Cruz de la Sierra. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Santa Cruz de la Sierra from North Carolina?

    Located just 11.5 mi from the city center, Santa Cruz de la Sierra Viru Viru Intl (VVI) is the airport most travelers will use when flying to Santa Cruz de la Sierra from North Carolina.

  • Can I find deals for flights from North Carolina to Santa Cruz de la Sierra that include hotel bookings?

    Yes. In addition to deals on North Carolina to Santa Cruz de la Sierra flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from North Carolina to Santa Cruz de la Sierra?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from North Carolina to Santa Cruz de la Sierra.

  • Can I find deals for business class flights from North Carolina to Santa Cruz de la Sierra?

    Yes. Cheapflights offers flight deals from North Carolina to Santa Cruz de la Sierra by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from North Carolina to Santa Cruz de la Sierra?

    Currently, October is the cheapest month in which you can book a flight from North Carolina to Santa Cruz de la Sierra (average of $597). Flying from North Carolina to Santa Cruz de la Sierra in December is currently the most expensive (average of $822). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for North Carolina to Santa Cruz de la Sierra

See prices for flight routes from nearby airports that may be better suited for you.
Miami to Santa Cruz de la Sierra flights
Dulles Intl to Santa Cruz de la Sierra flights
John F Kennedy Intl to La Paz flights
Dulles Intl to La Paz flights
Miami to La Paz flights
Miami to Cochabamba flights
John F Kennedy Intl to Santa Cruz de la Sierra flights
Reagan-National to Santa Cruz de la Sierra flights
Dulles Intl to Cochabamba flights
Orlando to Santa Cruz de la Sierra flights
Los Angeles to Santa Cruz de la Sierra flights
Baltimore to Santa Cruz de la Sierra flights
Newark to Santa Cruz de la Sierra flights
LaGuardia to La Paz flights
Los Angeles to La Paz flights
Newark to La Paz flights
O'Hare Intl to La Paz flights
LaGuardia to Santa Cruz de la Sierra flights
Reagan-National to La Paz flights
San Francisco to La Paz flights
Baltimore to La Paz flights
Charlotte to La Paz flights
Dallas/Fort Worth to Cochabamba flights
Boston to Santa Cruz de la Sierra flights
Seattle to Santa Cruz de la Sierra flights
San Francisco to Santa Cruz de la Sierra flights
Fort Lauderdale to La Paz flights
Hobby to Santa Cruz de la Sierra flights
George Bush Intcntl to Santa Cruz de la Sierra flights
O'Hare Intl to Santa Cruz de la Sierra flights
Raleigh to La Paz flights
Boston to La Paz flights
Baltimore to Cochabamba flights
Indianapolis to La Paz flights
Indianapolis to Santa Cruz de la Sierra flights
Hobby to La Paz flights
Orlando to La Paz flights
San Diego to La Paz flights
Dallas/Fort Worth to La Paz flights
Dallas/Fort Worth to Santa Cruz de la Sierra flights
George Bush Intcntl to La Paz flights
John F Kennedy Intl to Uyuni flights
Omaha to Santa Cruz de la Sierra flights
Atlanta to Santa Cruz de la Sierra flights
Reagan-National to Cochabamba flights
John F Kennedy Intl to Trinidad flights

Top 2 airlines flying from North Carolina to Santa Cruz de la Sierra

Discover the top 2 airlines that operate flights from North Carolina to Santa Cruz de la Sierra. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 30, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$367Average$679FlexibilityNo cancel feeOn-time69%
Copa AirlinesCheapest$379Average$522FlexibilityNo cancel feeOn-time70%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.