$185+ Cheap flights from Key West to Santa Ana, CA (EYW - SNA)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/1. Fares are subject to change and may not be available on all flights or dates of travel.
EYW — SNA
Mar 1 — Mar 81
1 adult, Economy
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1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Key West to Santa Ana
Cheapest
Best
Last-minute
One-way
Cheapest flights from Key West to Santa AnaExplore the most affordable flight options available from Key West to Santa Ana. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 30, 2026.
Explore the most affordable flight options available from Key West to Santa Ana. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 30, 2026.
This United Airlines deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/266:35 pm
EYW
- SNA
2 stops30h 55m
United Airlines
Mon 3/24:15 pm
SNA
- EYW
2 stops19h 45m
United Airlines
Deal found 1/28![United Airlines logo]()
$588
Best flights from Key West to Santa AnaDiscover carefully curated flight deals from Key West to Santa Ana that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated January 30, 2026.
Discover carefully curated flight deals from Key West to Santa Ana that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated January 30, 2026.
This United Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/266:35 pm
EYW
- SNA
2 stops30h 55m
United Airlines
Mon 3/24:15 pm
SNA
- EYW
2 stops22h 39m
United Airlines
Deal found 1/27![United Airlines logo]()
$588
Last-minute flights from Key West to Santa AnaDiscover last-minute flight deals from Key West to Santa Ana. Data last updated January 30, 2026 and is based on user searches.
Discover last-minute flight deals from Key West to Santa Ana. Data last updated January 30, 2026 and is based on user searches.
This United Airlines deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/266:35 pm
EYW
- SNA
2 stops30h 55m
United Airlines
Mon 3/24:15 pm
SNA
- EYW
2 stops19h 45m
United Airlines
Deal found 1/28![United Airlines logo]()
$588
One-way flights from Key West to Santa AnaSearch for one-way flight options from Key West to Santa Ana. Find affordable one-way fares based on user searches. Data last updated January 30, 2026.
Search for one-way flight options from Key West to Santa Ana. Find affordable one-way fares based on user searches. Data last updated January 30, 2026.
This Mytrip deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/12:25 pm
EYW
- SNA
2 stops25h 00m
Spirit Airlines
Deal found 1/28![Spirit Airlines logo]()
$185
This American Airlines deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/16:53 pm
EYW
- SNA
1 stop18h 58m
American Airlines
Deal found 1/28![American Airlines logo]()
$1,135
Find flight deals from Key West to Santa Ana
Discover tips and strategies to find the most affordable flight options for your journey from Key West (EYW) to Santa Ana (SNA). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated January 30, 2026.
Most accurate provider | Expedia 1 star |
|---|---|
Most trusted provider | Expedia 3 stars |
Round-trip from | $588 (United Airlines) |
One-way from | $185 (Mytrip) |
Cheapflights Fare Finder
Customize your flight search to find flights from Key West to Santa Ana that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 30, 2026.
Use the filters below to find and compare flights from Key West to Santa Ana that are best for you.
Fly from
Key West
Fly to
Santa Ana
Route
Depart
Return
Price
Key WestSanta Ana
EYW - SNA
EYWSNA
Key West
Thu 2/26
6:35 pm-10:30 pm
2 stops30h 55m
Santa Ana J. Wayne/Orange Cnty
Mon 3/2
4:15 pm-5:54 pm
2 stops22h 39m
$588
Key WestSanta Ana
EYW - SNA
EYWSNA
Key West
Sun 3/1
2:25 pm-12:25 pm
2 stops25h 00m
$185
Key WestSanta Ana
EYW - SNA
EYWSNA
Key West
Sun 3/1
6:53 pm-10:51 am
1 stop18h 58m
$1,135
- Most accurate provider: When it comes to deals on Key West-Santa Ana, California flights, users find the pricing of Expedia to be most consistent on Cheapflights vs. Expedia Users can find the same prices on Key West-Santa Ana, California flight deals on Cheapflights vs. Expedia <90% of the time. Price accuracy is based on data collected from Key West-Santa Ana, California flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Key West-Santa Ana, California flights, Cheapflights users trust Expedia the most. Expedia has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Key West-Santa Ana, California flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Key West to Santa Ana
Have a flexible travel schedule? Discover the best time to fly to Santa Ana from Key West with our price prediction graph.
EYW-SNA
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Reviews of airlines servicing Santa Ana
Get insights into the airlines that provide service to Santa Ana. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santa Ana. Reviews last updated January 30, 2026.
Read reviews from past customers who have flown American Airlines from Key West to Santa Ana. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Boarding
7.5
Crew
8.0
Entertainment
6.9
Overall
7.2
Comfort
7.2
Food
6.4
Reviews
1 / 20
4.0
OkaySusie,Jan 2026
TPA - CLT
Boarding
7.5
Crew
8.0
Entertainment
6.9
Overall
7.2
Comfort
7.2
Food
6.4
Reviews
1 / 20
4.0
OkaySusie,Jan 2026
TPA - CLT
Related info for your journey
Find useful and relevant information for your journey from Key West to Santa Ana. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Santa Ana?
Book flights to Santa Ana if you plan to visit one of these locationsTustin
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Alternative routes for Key West to Santa Ana
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Top airline flying from Key West to Santa Ana
Discover the top airline that operate flights from Key West to Santa Ana. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 30, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$338 | Average$479 | FlexibilityNo cancel fee | On-time71% |