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$377+ Cheap flights from Key West to Santa Ana (EYW - SNA)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/21. Fares are subject to change and may not be available on all flights or dates of travel.
EYW — SNA
Aug 5 — Aug 121
Tue 8/5
Tue 8/12
1 adult, Economy
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Cheap flight deals from Key West to Santa Ana

Discover tips and strategies to find the most affordable flight options for your journey from Key West (EYW) to Santa Ana (SNA). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated July 31, 2025.

Round-trip from

$377
(American Airlines)

Popular in

July

Cheapest in

September

Average price

$952
From Key West to Santa Ana J. Wayne/Orange Cnty
Search Deals
Highest demand for flights based on searches. 22% potential increase in price ($153 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 10% potential price decrease ($48 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in July 2025
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Find flight deals from Key West to Santa Ana

Cheapest flights from Key West to Santa Ana
Explore the most affordable flight options available from Key West to Santa Ana. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 31, 2025.

This American Airlines deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/212:31 pmEYW - SNA
1 stop8h 27mAmerican Airlines
Sat 8/304:19 pmSNA - EYW
2 stops16h 40mAmerican Airlines
Deal found 7/31$377
This Delta deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/2111:52 amEYW - SNA
1 stop8h 21mDelta
Sat 8/306:45 amSNA - EYW
1 stop10h 27mDelta
Deal found 7/31$459
This Mytrip deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/2110:02 amEYW - SNA
2 stops28h 27mMultiple Airlines
Sat 8/308:30 pmSNA - EYW
3 stops13h 37mMultiple Airlines
Deal found 7/31$495

Cheapflights Fare Finder

 
Customize your flight search to find flights from Key West to Santa Ana that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 31, 2025.
Use the filters below to find and compare flights from Key West to Santa Ana that are best for you.

Fly from

Key West

Fly to

Santa Ana

Route

Depart

Return

Price

Key WestSanta Ana

EYW - SNA

EYWSNA

Key West

Thu 8/21

2:31 pm-7:58 pm

1 stop8h 27m

Santa Ana J. Wayne/Orange Cnty

Sat 8/30

4:19 pm-11:59 am

2 stops16h 40m

$377

Key WestSanta Ana

EYW - SNA

EYWSNA

Key West

Thu 8/21

11:52 am-5:13 pm

1 stop8h 21m

Santa Ana J. Wayne/Orange Cnty

Sat 8/30

6:45 am-8:12 pm

1 stop10h 27m

$459

Key WestSanta Ana

EYW - SNA

EYWSNA

Key West

Thu 8/21

10:02 am-11:29 am

2 stops28h 27m

Santa Ana J. Wayne/Orange Cnty

Sat 8/30

8:30 pm-1:07 pm

3 stops13h 37m

$495

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/31

Best time to book a flight from Key West to Santa Ana

Have a flexible travel schedule? Discover the best time to fly to Santa Ana from Key West with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Reviews of airlines servicing Santa Ana

Get insights into the airlines that provide service to Santa Ana. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santa Ana. Reviews last updated July 31, 2025.
Read reviews from past customers who have flown Delta and American Airlines from Key West to Santa Ana. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,981 reviews

Comfort

7.9

Boarding

8.2

Crew

8.5

Entertainment

7.9

Overall

8.0

Food

7.3

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
Delta
8.0
Very good
7,981 reviews
Delta
8.0
Very good
7,981 reviews

Comfort

7.9

Boarding

8.2

Crew

8.5

Entertainment

7.9

Overall

8.0

Food

7.3

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,981 reviews

Comfort

7.9

Boarding

8.2

Crew

8.5

Entertainment

7.9

Overall

8.0

Food

7.3

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Related info for your journey

Find useful and relevant information for your journey from Key West to Santa Ana. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines flying from Key West to Santa Ana round-trip?

    Cheapflights users have booked flights from Key West to Santa Ana round-trip from $377. Another airline that can offer you cheap pricing is Delta.

  • Can I find deals for flights from Key West to Santa Ana that include hotel bookings?

    Yes. In addition to deals on Key West to Santa Ana flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Key West to Santa Ana?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Key West to Santa Ana.

  • Can I find deals for business class flights from Key West to Santa Ana?

    Yes. Cheapflights offers flight deals from Key West to Santa Ana by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Key West to Santa Ana?

    Currently, January is the cheapest month in which you can book a flight from Key West to Santa Ana (average of $298). Flying from Key West to Santa Ana in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Santa Ana?

Book flights to Santa Ana if you plan to visit one of these locations
Tustin

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Top 3 airlines flying from Key West to Santa Ana

Discover the top 3 airlines that operate flights from Key West to Santa Ana. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 31, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$338Average$498FlexibilityNo cancel feeOn-time71%
DeltaCheapest$373Average$518FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$447Average$449FlexibilityNo cancel feeOn-time69%

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