How popular is this St. Louis to San Francisco flight route?

This flight path from Lambert-St Louis to San Francisco was viewed by 16 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

How long is the flight from St. Louis to San Francisco?

Delta and United Airlines can get you from St. Louis to San Francisco in just under 7h 17m. Your travel time can differ by up to 03m. The distance from St. Louis to San Francisco is about 1730 mi. Both multi-stop and nonstop flights can be found to your destination and back.

What are the cheapest airlines flying from St. Louis to San Francisco round-trip?

According to our current data, Frontier ($122), American Airlines ($182), and United Airlines ($247) offers the cheapest pricing from St. Louis to San Francisco. Frontier is currently priced 67% below the average price you’ll pay for this route.

Weekly flight availability from St. Louis to San Francisco

The most flights from STL to SFO are scheduled on a Monday (4 on average). You will have fewer flight options on Tuesday, which is when the least amount of flights are scheduled (1 on average).

In terms of precipitation, rainfall in San Francisco ranges from 0.0 - 4.4 inches per month. January is typically the wettest month, when rainfall can reach 4.4 in. July is typically the driest time to visit San Francisco when rainfall is around 0.0 in.

If weather is an important factor for your trip to San Francisco, use this chart to help with planning. For those seeking warmer temperatures, September is the ideal time of year to visit, when temperatures reach an average of 62.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 51.8 F).

What are the cheapest flights from St. Louis to San Francisco?

Looking for the cheapest flight from St. Louis to San Francisco? While on average our users pay $590, our data indicates the cheapest price to be $126. The most popular route (Lambert-St Louis - San Francisco), is priced around $233.

What are the most reliable airlines from St. Louis to San Francisco?

The top 3 most reliable airlines when flying from St. Louis to San Francisco are Asiana Airlines (83%), Air New Zealand (83%) and SkyWest Airlines (63%).

What are the most popular airlines that fly from St. Louis to San Francisco?

When booking a flight from St. Louis to San Francisco, you may want to consider flying on United Airlines, Southwest or Frontier as they are the most popular for this route.

Most accurate provider : When it comes to deals on St. Louis-San Francisco flights, users find the pricing of Gotogate to be most consistent on Cheapflights vs. Gotogate Users can find the same prices on St. Louis-San Francisco flight deals on Cheapflights vs. Gotogate >95% of the time. Price accuracy is based on data collected from St. Louis-San Francisco flight searches over the past month and is updated monthly.

Most trusted provider : When it comes to deals on St. Louis-San Francisco flights, Cheapflights users trust Gotogate the most. Gotogate has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for St. Louis-San Francisco flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

What airports do I use to fly from St. Louis to San Francisco?

If you wish to fly to San Francisco from St. Louis, then you need to book flights from Lambert-St Louis to San Francisco. There are 2 flights from Lambert-St Louis (STL) to San Francisco (SFO) per day to choose from. Flights to San Francisco from Lambert-St Louis are available from 5 different airlines, which means you should have some options if you want to compare airfare deals. 4h 20m is how long a nonstop flight from St. Louis to San Francisco typically takes.

Can I find deals for flights from St. Louis to San Francisco that include hotel bookings?

Yes. In addition to deals on St. Louis to San Francisco flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from St. Louis to San Francisco?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from St. Louis to San Francisco.

Can I find deals for business class flights from St. Louis to San Francisco?

Yes. Cheapflights offers flight deals from St. Louis to San Francisco by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$62+ Flights from St. Louis to San Francisco

Q: How much does it cost to fly round-trip from St. Louis to San Francisco?

Airfare is below average for this route at the moment. St. Louis to San Francisco flights typically cost between $261 and $429 in December. The cheapest round-trip price found within the last 3 days was $197 on Frontier (Dec 19-Jan 4).

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Find cheap flights from St. Louis to San Francisco with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheapflights Tip: The best prices from Lambert-St Louis to San Francisco are usually found in January or February, booked 76 days in advance, depart on a Thursday or Saturday and return on a Wednesday

Cheap flight deals from St. Louis to San Francisco

Most accurate provider	Gotogate 3 stars
Most trusted provider	Gotogate 3 stars
Round-trip from	$197 (Kiwi.com)
One-way from	$62 (Trip.com)
Popular in	July
Cheapest in	January
Average price	$348
Good round-trip deal	$509 or less
Good one-way deal	$215 or less

Provider with most accurate pricing for Lambert-St Louis-San Francisco flight deals.

Search Deals

Provider most trusted by Cheapflights users for Lambert-St Louis-San Francisco flights.

Search Deals

From Lambert-St Louis to San Francisco

Search Deals

One-way flight from Lambert-St Louis to San Francisco

Search Deals

Highest demand for flights based on searches. 8% potential increase in price ($36 potential increase over avg. RT price).

Search Deals

Cheapest flight prices on average. 1% potential price decrease ($6 potential savings vs. average RT price).

Search Deals

Average for round-trip flights in October 2025

Search Deals

Price to beat on a round-trip flight from Lambert-St Louis to San Francisco.

Search Deals

Price to beat on a one-way flight from Lambert-St Louis to San Francisco.

Search Deals

Find flight deals from St. Louis to San Francisco

Cheapest flights from St. Louis to San Francisco
Explore the most affordable flight options available from St. Louis to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 27, 2025.

Fri 12/197:43 pmSTL - SFO

2 stops51h 18mFrontier

Sun 1/49:56 pmSFO - STL

1 stop20h 11mFrontier

Deal found 10/25

$197

Fri 11/77:45 pmSTL - SFO

2 stops27h 26mFrontier

Sun 11/168:55 pmSFO - STL

1 stop12h 29mFrontier

Deal found 10/25

$203

Wed 10/298:40 pmSTL - SFO

1 stop14h 53mFrontier

Wed 12/106:00 amSFO - STL

1 stop28h 12mFrontier

Deal found 10/25

$206

Mon 11/247:43 pmSTL - SFO

1 stop14h 25mFrontier

Wed 12/36:00 amSFO - STL

1 stop28h 12mFrontier

Deal found 10/27

$207

Fri 10/311:09 pmSTL - SFO

1 stop6h 34mFrontier

Tue 12/96:30 amSFO - STL

1 stop25h 44mFrontier

Deal found 10/25

$208

Tue 12/2310:10 pmSTL - SFO

1 stop16h 24mFrontier

Fri 1/99:13 amSFO - STL

1 stop22h 49mFrontier

Deal found 10/25

$209

Tue 11/117:45 pmSTL - SFO

2 stops22h 58mFrontier

Tue 11/188:02 amSFO - STL

1 stop23h 05mFrontier

Deal found 10/27

$210

Mon 12/812:07 pmSTL - SFO

1 stop7h 27mFrontier

Wed 12/106:30 amSFO - STL

2 stops26h 37mFrontier

Deal found 10/27

$211

Sat 12/207:43 pmSTL - SFO

1 stop14h 40mFrontier

Sun 1/49:56 pmSFO - STL

1 stop20h 11mFrontier

Deal found 10/25

$214

Tue 11/117:45 pmSTL - SFO

2 stops22h 58mFrontier

Mon 11/176:34 amSFO - STL

1 stop24h 33mFrontier

Deal found 10/27

$221

Wed 11/57:45 pmSTL - SFO

1 stop15h 48mFrontier

Mon 11/103:25 pmSFO - STL

1 stop15h 42mFrontier

Deal found 10/26

$222

Best flights from St. Louis to San Francisco
Discover carefully curated flight deals from St. Louis to San Francisco that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 27, 2025.

Thu 11/276:00 amSTL - SFO

1 stop7h 17mDelta

Wed 12/31:58 pmSFO - STL

2 stops9h 03mDelta

Deal found 10/27

$306

Sat 1/104:15 pmSTL - SFO

1 stop7h 20mUnited Airlines

Sat 1/1712:43 amSFO - STL

1 stop6h 39mUnited Airlines

Deal found 10/26

$373

Thu 12/116:15 amSTL - SFO

2 stops11h 42mDelta

Fri 1/1612:47 amSFO - STL

1 stop7h 54mDelta

Deal found 10/26

$311

Mon 12/83:19 pmSTL - SFO

1 stop8h 10mUnited Airlines

Sat 12/1310:35 amSFO - STL

Nonstop3h 54mUnited Airlines

Deal found 10/26

$391

Wed 12/312:49 pmSTL - SFO

2 stops11h 42mDelta

Thu 12/412:30 amSFO - STL

1 stop6h 40mDelta

Deal found 10/27

$388

Wed 12/35:30 pmSTL - SFO

Nonstop4h 38mUnited Airlines

Thu 12/412:43 amSFO - STL

1 stop7h 21mUnited Airlines

Deal found 10/27

$443

Thu 12/256:29 amSTL - SFO

2 stops13h 13mDelta

Sun 12/286:00 amSFO - STL

1 stop5h 23mDelta

Deal found 10/25

$419

Thu 12/115:30 pmSTL - SFO

Nonstop4h 38mUnited Airlines

Sat 1/1711:00 pmSFO - STL

Nonstop4h 11mUnited Airlines

Deal found 10/25

$446

Thu 11/276:40 amSTL - SFO

1 stop9h 35mDelta

Mon 12/11:58 pmSFO - STL

2 stops8h 48mDelta

Deal found 10/26

$426

Tue 11/116:00 amSTL - SFO

2 stops11h 57mDelta

Sat 11/1512:30 amSFO - STL

1 stop6h 25mDelta

Deal found 10/26

$456

Fri 11/146:00 amSTL - SFO

2 stops11h 57mDelta

Sun 11/1610:30 pmSFO - STL

1 stop7h 58mDelta

Deal found 10/26

$467

Last-minute flights from St. Louis to San Francisco
Discover last-minute flight deals from St. Louis to San Francisco. Data last updated October 27, 2025 and is based on user searches.

Wed 10/298:40 pmSTL - SFO

1 stop14h 53mFrontier

Wed 12/106:00 amSFO - STL

1 stop28h 12mFrontier

Deal found 10/25

$206

Fri 10/311:09 pmSTL - SFO

1 stop6h 34mFrontier

Tue 12/96:30 amSFO - STL

1 stop25h 44mFrontier

Deal found 10/25

$208

Fri 10/311:09 pmSTL - SFO

1 stop6h 34mFrontier

Fri 12/128:48 amSFO - STL

1 stop23h 26mFrontier

Deal found 10/25

$225

Wed 11/57:45 pmSTL - SFO

1 stop15h 48mFrontier

Mon 11/105:45 amSFO - STL

1 stop6h 12mFrontier

Deal found 10/27

$222

Thu 11/611:07 amSTL - SFO

1 stop12h 04mFrontier

Sun 11/168:55 pmSFO - STL

1 stop12h 29mFrontier

Deal found 10/25

$228

Fri 11/77:45 pmSTL - SFO

2 stops27h 26mFrontier

Sun 11/168:55 pmSFO - STL

1 stop12h 29mFrontier

Deal found 10/25

$203

Tue 11/117:45 pmSTL - SFO

2 stops22h 58mFrontier

Tue 11/188:02 amSFO - STL

1 stop23h 05mFrontier

Deal found 10/27

$210

Tue 11/117:45 pmSTL - SFO

2 stops22h 58mFrontier

Mon 11/176:34 amSFO - STL

1 stop24h 33mFrontier

Deal found 10/27

$221

Wed 11/127:45 pmSTL - SFO

1 stop15h 48mFrontier

Tue 11/188:02 amSFO - STL

1 stop23h 05mFrontier

Deal found 10/27

$229

Thu 11/136:22 pmSTL - SFO

2 stops24h 21mFrontier

Mon 11/173:35 pmSFO - STL

1 stop15h 32mFrontier

Deal found 10/26

$226

Mon 11/247:43 pmSTL - SFO

1 stop14h 25mFrontier

Wed 12/36:00 amSFO - STL

1 stop28h 12mFrontier

Deal found 10/27

$207

One-way flights from St. Louis to San Francisco
Search for one-way flight options from St. Louis to San Francisco. Find affordable one-way fares based on user searches. Data last updated October 27, 2025.

Wed 12/107:43 pmSTL - SFO

1 stop14h 10mFrontier

Deal found 10/26

$62

Sat 1/107:43 pmSTL - SFO

1 stop14h 30mFrontier

Deal found 10/26

$63

Mon 12/812:07 pmSTL - SFO

1 stop7h 27mFrontier

Deal found 10/25

$65

Wed 12/37:43 pmSTL - SFO

1 stop14h 10mFrontier

Deal found 10/26

$67

Mon 1/127:43 pmSTL - SFO

1 stop28h 28mFrontier

Deal found 10/25

$68

Wed 11/197:45 pmSTL - SFO

1 stop14h 23mFrontier

Deal found 10/27

$71

Sun 1/255:44 pmSTL - SFO

1 stop16h 04mFrontier

Deal found 10/25

$76

Sun 1/119:47 pmSTL - SFO

1 stop12h 01mFrontier

Deal found 10/26

$80

Mon 1/199:47 pmSTL - SFO

1 stop26h 47mFrontier

Deal found 10/26

$85

Mon 12/151:16 pmSTL - SFO

1 stop29h 35mFrontier

Deal found 10/25

$91

Wed 1/77:43 pmSTL - SFO

2 stops20h 38mFrontier

Deal found 10/25

$100

Cheapflights Fare Finder

Use the filters below to find and compare flights from St. Louis to San Francisco that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

St. LouisSan Francisco

STL - SFO

STLSFO

Lambert-St Louis

Thu 11/27

6:00 am-11:17 am

1 stop7h 17m

San Francisco

Wed 12/3

1:58 pm-1:01 am

2 stops9h 03m

$306

St. LouisSan Francisco

STL - SFO

STLSFO

Lambert-St Louis

Thu 12/11

6:15 am-3:57 pm

2 stops11h 42m

San Francisco

Fri 1/16

12:47 am-10:41 am

1 stop7h 54m

$311

St. LouisSan Francisco

STL - SFO

STLSFO

Lambert-St Louis

Sat 1/10

4:15 pm-9:35 pm

1 stop7h 20m

San Francisco

Sat 1/17

12:43 am-9:22 am

1 stop6h 39m

$373

St. LouisSan Francisco

STL - SFO

STLSFO

Lambert-St Louis

Wed 12/3

12:49 pm-10:31 pm

2 stops11h 42m

San Francisco

Thu 12/4

12:30 am-9:10 am

1 stop6h 40m

$388

St. LouisSan Francisco

STL - SFO

STLSFO

Lambert-St Louis

Mon 12/8

3:19 pm-9:29 pm

1 stop8h 10m

San Francisco

Sat 12/13

10:35 am-4:29 pm

Nonstop3h 54m

$391

St. LouisSan Francisco

STL - SFO

STLSFO

Lambert-St Louis

Thu 12/25

6:29 am-5:42 pm

2 stops13h 13m

San Francisco

Sun 12/28

6:00 am-1:23 pm

1 stop5h 23m

$419

St. LouisSan Francisco

STL - SFO

STLSFO

Lambert-St Louis

Thu 11/27

6:40 am-2:15 pm

1 stop9h 35m

San Francisco

Mon 12/1

1:58 pm-12:46 am

2 stops8h 48m

$426

St. LouisSan Francisco

STL - SFO

STLSFO

Lambert-St Louis

Wed 12/3

5:30 pm-8:08 pm

Nonstop4h 38m

San Francisco

Thu 12/4

12:43 am-10:04 am

1 stop7h 21m

$443

St. LouisSan Francisco

STL - SFO

STLSFO

Lambert-St Louis

Thu 12/11

5:30 pm-8:08 pm

Nonstop4h 38m

San Francisco

Sat 1/17

11:00 pm-5:11 am

Nonstop4h 11m

$446

St. LouisSan Francisco

STL - SFO

STLSFO

Lambert-St Louis

Tue 11/11

6:00 am-3:57 pm

2 stops11h 57m

San Francisco

Sat 11/15

12:30 am-8:55 am

1 stop6h 25m

$456

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/26

Showing 1-10 of 20 results

Compare providers for flights from St. Louis to San Francisco

Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from St. Louis to San Francisco in October.

Provider	Price Accuracy	Trust Score*
Expedia	Price Accuracy2 stars	Trust Score*3 stars
FlightHub	Price Accuracy3 stars	Trust Score*1 star
eDreams	Price Accuracy3 stars	Trust Score*3 stars
Priceline	Price Accuracy1 star	Trust Score*3 stars
JustAirTicket	Price Accuracy-	Trust Score*1 star
Gotogate	Price Accuracy3 stars	Trust Score*3 stars
Cheapfaremart	Price Accuracy-	Trust Score*1 star

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

Most accurate provider: When it comes to deals on St. Louis-San Francisco flights, users find the pricing of Gotogate to be most consistent on Cheapflights vs. Gotogate Users can find the same prices on St. Louis-San Francisco flight deals on Cheapflights vs. Gotogate >95% of the time. Price accuracy is based on data collected from St. Louis-San Francisco flight searches over the past month and is updated monthly.
Most trusted provider: When it comes to deals on St. Louis-San Francisco flights, Cheapflights users trust Gotogate the most. Gotogate has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for St. Louis-San Francisco flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from St. Louis to San Francisco

Have a flexible travel schedule? Discover the best time to fly to San Francisco from St. Louis with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from St. Louis to San Francisco

Prices

Airlines

How far ahead should I book a flight from St. Louis to San Francisco?

The best time to book flights from St. Louis to San Francisco is 76 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from St. Louis to San Francisco?

Currently, August is the cheapest month in which you can book a flight from St. Louis to San Francisco (average of $123). Flying from St. Louis to San Francisco in May is currently the most expensive (average of $256). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from STL to SFO?

It’s typically best to fly out from St. Louis to San Francisco at noon. Doing so could potentially save you 60% on the flight price compared to flying in the evening, which is usually more expensive.

What is the cheapest day to fly from St. Louis to San Francisco?

Travelers seeking maximum savings on their St. Louis to San Francisco flight should consider departing on Wednesday at noon when fares are most often at their lowest. Monday evenings flights should be avoided if possible as fares are typically the most expensive at this time.

How much does it cost to fly round-trip from St. Louis to San Francisco?

The best insider tips for St. Louis to San Francisco flights

Cheapflights partnered with top experts to bring you the best recommendations for your St. Louis to San Francisco trip

Airports

STL

Security lines at STL are generally quick, averaging 5-10 minutes off-peak. Check real-time wait times online before heading to the airport.

SFO

For a budget-friendly trip from SFO to downtown, take BART. It's a 40-minute ride from the airport.

Our travel experts

Taryn White

Expert on STL

Harriet Baskas

Expert on SFO

Reviews of airlines servicing San Francisco

Read through reviews of airlines operating flights from St. Louis to San Francisco, such as Southwest, Delta, and United Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.

Southwest

8.0

Very good

4,236 reviews

Reviews

1 / 20

8.0

Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.

Southwest

8.0

Very good

4,236 reviews

Southwest

8.0

Very good

4,236 reviews

Reviews

1 / 20

8.0

Excellent

Walter,Aug 2025

OAK - SAN

Delta

7.9

Good

7,996 reviews

Southwest

8.0

Very good

4,236 reviews

Reviews

1 / 20

8.0

Excellent

Walter,Aug 2025

OAK - SAN

United Airlines

7.4

Good

8,997 reviews

Southwest

8.0

Very good

4,236 reviews

Reviews

1 / 20

8.0

Excellent

Walter,Aug 2025

OAK - SAN

American Airlines

7.2

Good

11,033 reviews

Southwest

8.0

Very good

4,236 reviews

Reviews

1 / 20

8.0

Excellent

Walter,Aug 2025

OAK - SAN

Frontier

5.8

Fair

3,122 reviews

Southwest

8.0

Very good

4,236 reviews

Reviews

1 / 20

8.0

Excellent

Walter,Aug 2025

OAK - SAN

Related info for your journey

What airports do I use to fly from St. Louis to San Francisco?
If you wish to fly to San Francisco from St. Louis, then you need to book flights from Lambert-St Louis to San Francisco. There are 2 flights from Lambert-St Louis (STL) to San Francisco (SFO) per day to choose from. Flights to San Francisco from Lambert-St Louis are available from 5 different airlines, which means you should have some options if you want to compare airfare deals. 4h 20m is how long a nonstop flight from St. Louis to San Francisco typically takes.
How popular is this St. Louis to San Francisco flight route?
This flight path from Lambert-St Louis to San Francisco was viewed by 16 users in the past month. Keep an eye out for changes in search interest prior to high and low season.
How long is the flight from St. Louis to San Francisco?
Delta and United Airlines can get you from St. Louis to San Francisco in just under 7h 17m. Your travel time can differ by up to 03m. The distance from St. Louis to San Francisco is about 1730 mi. Both multi-stop and nonstop flights can be found to your destination and back.
What are the cheapest airlines flying from St. Louis to San Francisco round-trip?
According to our current data, Frontier ($122), American Airlines ($182), and United Airlines ($247) offers the cheapest pricing from St. Louis to San Francisco. Frontier is currently priced 67% below the average price you’ll pay for this route.
What are the most reliable airlines from St. Louis to San Francisco?
The top 3 most reliable airlines when flying from St. Louis to San Francisco are Asiana Airlines (83%), Air New Zealand (83%) and SkyWest Airlines (63%).
What are the cheapest flights from St. Louis to San Francisco?
Looking for the cheapest flight from St. Louis to San Francisco? While on average our users pay $590, our data indicates the cheapest price to be $126. The most popular route (Lambert-St Louis - San Francisco), is priced around $233.
Can I find deals for flights from St. Louis to San Francisco that include hotel bookings?
Yes. In addition to deals on St. Louis to San Francisco flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from St. Louis to San Francisco?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from St. Louis to San Francisco.
Can I find deals for business class flights from St. Louis to San Francisco?
Yes. Cheapflights offers flight deals from St. Louis to San Francisco by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from St. Louis to San Francisco?
Currently, August is the cheapest month in which you can book a flight from St. Louis to San Francisco (average of $123). Flying from St. Louis to San Francisco in May is currently the most expensive (average of $256). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Roseville

South San Francisco

Santa Cruz

Livermore

Turlock

Watsonville

Sunnyvale

Santa Clara

Antioch

Manteca

Vallejo

Hollister

Vacaville

San Bruno

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Union City

Fairfield

Burlingame

Lodi

Browse thousands of different options on Cheapflights for your next trip

Top 5 airlines flying from St. Louis to San Francisco

Airline	Cheapest	Average	Flexibility	On-time
Frontier	Cheapest$122	Average$220	FlexibilityNo cancel fee	On-time62%
American Airlines	Cheapest$182	Average$334	FlexibilityNo cancel fee	On-time71%
United Airlines	Cheapest$238	Average$407	FlexibilityNo cancel fee	On-time69%
Delta	Cheapest$256	Average$368	FlexibilityNo cancel fee	On-timeN/A
Southwest	Cheapest$305	Average$443	FlexibilityNo cancel fee	On-time63%

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$62+ Cheap flights from St. Louis to San Francisco (STL - SFO)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/10. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from St. Louis to San Francisco with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Cheapflights Tip: The best prices from Lambert-St Louis to San Francisco are usually found in January or February, booked 76 days in advance, depart on a Thursday or Saturday and return on a Wednesday

Cheap flight deals from St. Louis to San Francisco

Most accurate provider

Most trusted provider

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Good round-trip deal

Good one-way deal

Find flight deals from St. Louis to San Francisco

Cheapest flights from St. Louis to San FranciscoExplore the most affordable flight options available from St. Louis to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 27, 2025.

Explore the most affordable flight options available from St. Louis to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 27, 2025.

Cheapflights Fare Finder

Use the filters below to find and compare flights from St. Louis to San Francisco that are best for you.

Compare providers for flights from St. Louis to San Francisco

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Everything you need to know about your flight from St. Louis to San Francisco

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Reviews of airlines servicing San Francisco

Read through reviews of airlines operating flights from St. Louis to San Francisco, such as Southwest, Delta, and United Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from St. Louis to San Francisco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

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Alternative routes for St. Louis to San Francisco

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Top 5 airlines flying from St. Louis to San Francisco

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Cheapest flights from St. Louis to San Francisco
Explore the most affordable flight options available from St. Louis to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 27, 2025.