$411+ Cheap flights from Santiago (SCL) to San Francisco (SFO)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/22. Fares are subject to change and may not be available on all flights or dates of travel.
SCL — SFO
Dec 7 — Dec 141
Round-trip
1 adult, Economy
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Find cheap flights from Santiago to San Francisco with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Santiago to San Francisco
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Cheapest flights from Santiago to San FranciscoExplore the most affordable flight options available from Santiago to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 7, 2026.
Explore the most affordable flight options available from Santiago to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 7, 2026.
This Avianca deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/97:30 am -
2 stops19h 10m
Thu 12/311:15 pm -
2 stops20h 55m
Deal found 11/4![Avianca logo]()
$811
This Avianca deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/127:30 am -
2 stops19h 10m
Mon 11/1611:00 pm -
2 stops21h 05m
Deal found 11/4![Avianca logo]()
$831
This LATAM Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/2411:55 pm -
1 stop17h 04m
Tue 1/127:00 am -
2 stops17h 20m
Deal found 11/3![LATAM Airlines logo]()
$841
This Rumbo deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Rumbo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/2411:55 pm -
1 stop17h 04m
Mon 1/119:59 am -
1 stop14h 36m
Deal found 11/2![LATAM Airlines logo]()
$844
This FlightHub deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/64:15 pm -
2 stops24h 40m
Tue 3/21:15 pm -
2 stops30h 50m
Deal found 11/2![Avianca logo]()
$858
This Justfly.com deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/14:15 pm -
2 stops48h 40m
Mon 12/71:15 pm -
2 stops35h 30m
Deal found 11/6![Avianca logo]()
$868
This Justfly.com deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/34:15 pm -
2 stops24h 40m
Tue 2/161:15 pm -
2 stops20h 55m
Deal found 11/2![Avianca logo]()
$870
This Avianca deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/77:30 am -
2 stops20h 25m
Sat 11/141:15 pm -
2 stops20h 55m
Deal found 11/6![Avianca logo]()
$878
This SmartFares deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure SmartFares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/84:15 pm -
2 stops48h 40m
Sun 11/1511:00 pm -
2 stops25h 45m
Deal found 11/4![Avianca logo]()
$880
This Delta deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/2411:00 pm -
1 stop26h 10m
Mon 1/116:05 am -
2 stops18h 50m
Deal found 11/2![Delta logo]()
$887
Best flights from Santiago to San FranciscoDiscover carefully curated flight deals from Santiago to San Francisco that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated November 7, 2026.
Discover carefully curated flight deals from Santiago to San Francisco that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated November 7, 2026.
This Delta deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/198:25 pm -
2 stops19h 10m
Sat 3/69:59 am -
2 stops24h 01m
Deal found 11/3![Delta logo]()
$887
This United Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/1910:45 pm -
1 stop30h 56m
Sat 3/64:45 pm -
1 stop35h 05m
Deal found 11/3![United Airlines logo]()
$894
This Delta deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/188:25 pm -
2 stops19h 10m
Thu 3/411:47 am -
2 stops22h 13m
Deal found 11/3![Delta logo]()
$887
This Delta deal was found by Cheapflights users on 11/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/48:25 pm -
2 stops24h 33m
Wed 2/1711:53 am -
1 stop14h 47m
Deal found 11/7![Delta logo]()
$930
This Delta deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/2511:00 pm -
1 stop26h 10m
Tue 12/296:05 am -
1 stop19h 35m
Deal found 11/5![Delta logo]()
$937
This Delta deal was found by Cheapflights users on 11/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/209:50 pm -
1 stop19h 52m
Fri 4/167:00 am -
2 stops19h 25m
Deal found 11/7![Delta logo]()
$937
This Delta deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 1/2411:00 pm -
1 stop24h 53m
Sun 1/315:10 pm -
2 stops19h 30m
Deal found 11/5![Delta logo]()
$937
This Delta deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/2811:00 pm -
1 stop18h 47m
Fri 1/15:20 pm -
2 stops16h 40m
Deal found 11/6![Delta logo]()
$937
Last-minute flights from Santiago to San FranciscoDiscover last-minute flight deals from Santiago to San Francisco. Data last updated November 7, 2026 and is based on user searches.
Discover last-minute flight deals from Santiago to San Francisco. Data last updated November 7, 2026 and is based on user searches.
This Avianca deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/77:30 am -
2 stops20h 25m
Sat 11/141:15 pm -
2 stops20h 55m
Deal found 11/6![Avianca logo]()
$878
This SmartFares deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure SmartFares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/84:15 pm -
2 stops48h 40m
Sun 11/1511:00 pm -
2 stops25h 45m
Deal found 11/4![Avianca logo]()
$880
This Avianca deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/127:30 am -
2 stops19h 10m
Mon 11/1611:00 pm -
2 stops21h 05m
Deal found 11/4![Avianca logo]()
$831
This Justfly.com deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/14:15 pm -
2 stops48h 40m
Mon 12/71:15 pm -
2 stops35h 30m
Deal found 11/6![Avianca logo]()
$868
This Justfly.com deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/34:15 pm -
2 stops24h 40m
Tue 2/161:15 pm -
2 stops20h 55m
Deal found 11/2![Avianca logo]()
$870
This FlightHub deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/64:15 pm -
2 stops24h 40m
Tue 3/21:15 pm -
2 stops30h 50m
Deal found 11/2![Avianca logo]()
$858
This Avianca deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/97:30 am -
2 stops19h 10m
Thu 12/311:15 pm -
2 stops20h 55m
Deal found 11/4![Avianca logo]()
$811
This LATAM Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/2411:55 pm -
1 stop17h 04m
Tue 1/127:00 am -
2 stops17h 20m
Deal found 11/3![LATAM Airlines logo]()
$841
This Rumbo deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Rumbo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/2411:55 pm -
1 stop17h 04m
Mon 1/119:59 am -
1 stop14h 36m
Deal found 11/2![LATAM Airlines logo]()
$844
One-way flights from Santiago to San FranciscoSearch for one-way flight options from Santiago to San Francisco. Find affordable one-way fares based on user searches. Data last updated November 7, 2026.
Search for one-way flight options from Santiago to San Francisco. Find affordable one-way fares based on user searches. Data last updated November 7, 2026.
This Kiwi.com deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/228:35 pm -
3 stops30h 59m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/2![Multiple Airlines logo]()
$411
This Kiwi.com deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/97:00 am -
3 stops55h 16m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/3![Multiple Airlines logo]()
$412
This Kiwi.com deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/88:35 pm -
3 stops48h 03m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/3![Multiple Airlines logo]()
$429
This Kiwi.com deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/1010:00 am -
3 stops34h 38m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/3![Multiple Airlines logo]()
$433
This Kiwi.com deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/238:35 pm -
3 stops52h 45m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/2![Multiple Airlines logo]()
$442
This Kiwi.com deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/219:25 am -
3 stops27h 24m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/4![Multiple Airlines logo]()
$457
Find flight deals from Santiago to San Francisco
Discover tips and strategies to find the most affordable flight options for your journey from Santiago (SCL) to San Francisco (SFO). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated November 7, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $811 (Avianca) |
One-way from | $411 (Kiwi.com) |
Popular in | October |
Cheapest in | February |
Average price | $828 |
Cheapflights Fare Finder
Customize your flight search to find flights from Santiago to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated November 7, 2026.
Use the filters below to find and compare flights from Santiago to San Francisco that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
SantiagoSan Francisco
SCL Santiago Arturo Merino Benitez - SFO San Francisco
SCLSFO
Santiago Arturo Merino Benitez
Thu 11/12
8:35 pm-11:17 am
3 stops43h 42m
San Francisco
Wed 12/31
12:00 am-5:00 am
Nonstop0h 00m
$484
SantiagoSan Francisco
SCL Santiago Arturo Merino Benitez - SFO San Francisco
SCLSFO
Santiago Arturo Merino Benitez
Sat 1/30
7:30 am-11:55 am
2 stops33h 25m
San Francisco
Wed 12/31
12:00 am-5:00 am
Nonstop0h 00m
$586
SantiagoSan Francisco
SCL Santiago Arturo Merino Benitez - SFO San Francisco
SCLSFO
Santiago Arturo Merino Benitez
Fri 12/25
7:06 am-10:34 pm
2 stops20h 28m
San Francisco
Wed 12/31
12:00 am-5:00 am
Nonstop0h 00m
$588
SantiagoSan Francisco
SCL Santiago Arturo Merino Benitez - SFO San Francisco
SCLSFO
Santiago Arturo Merino Benitez
Wed 11/25
1:02 am-4:38 pm
3 stops44h 36m
San Francisco
Wed 12/31
12:00 am-5:00 am
Nonstop0h 00m
$670
Quickest round-trip
SantiagoSan Francisco
SCL Santiago Arturo Merino Benitez - SFO San Francisco
SCLSFO
Santiago Arturo Merino Benitez
Mon 4/19
11:25 pm-11:04 am
1 stop14h 39m
San Francisco
Wed 12/31
12:00 am-5:00 am
Nonstop0h 00m
$690
SantiagoSan Francisco
SCL Santiago Arturo Merino Benitez - SFO San Francisco
SCLSFO
Santiago Arturo Merino Benitez
Thu 1/21
11:00 pm-6:53 pm
1 stop24h 53m
San Francisco
Wed 12/31
12:00 am-5:00 am
Nonstop0h 00m
$708
SantiagoSan Francisco
SCL Santiago Arturo Merino Benitez - SFO San Francisco
SCLSFO
Santiago Arturo Merino Benitez
Sat 1/23
9:50 pm-6:53 pm
1 stop26h 03m
San Francisco
Wed 12/31
12:00 am-5:00 am
Nonstop0h 00m
$708
SantiagoSan Francisco
SCL Santiago Arturo Merino Benitez - SFO San Francisco
SCLSFO
Santiago Arturo Merino Benitez
Sat 1/30
9:50 pm-5:24 pm
1 stop24h 34m
San Francisco
Wed 12/31
12:00 am-5:00 am
Nonstop0h 00m
$708
SantiagoSan Francisco
SCL Santiago Arturo Merino Benitez - SFO San Francisco
SCLSFO
Santiago Arturo Merino Benitez
Sat 11/14
5:07 am-11:12 pm
1 stop23h 05m
San Francisco
Wed 12/31
12:00 am-5:00 am
Nonstop0h 00m
$722
SantiagoSan Francisco
SCL Santiago Arturo Merino Benitez - SFO San Francisco
SCLSFO
Santiago Arturo Merino Benitez
Fri 2/19
8:25 pm-10:35 am
2 stops19h 10m
San Francisco
Sat 3/6
9:59 am-3:00 pm
2 stops24h 01m
$887
Showing 1-10 of 17 resultsSorted by cheapest first
Compare providers for flights from Santiago to San Francisco
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Santiago to San Francisco in November.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy2 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*2 stars |
- Most accurate provider: When it comes to deals on Santiago-San Francisco flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Santiago-San Francisco flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Santiago-San Francisco flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Santiago-San Francisco flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Santiago-San Francisco flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Santiago to San Francisco
Have a flexible travel schedule? Discover the best time to fly to San Francisco from Santiago with our price prediction graph.
SCL-SFO
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Santiago to San Francisco
How far ahead should I book a flight from Santiago to San Francisco?
The price you pay for your flight from Santiago to San Francisco may vary depending on when you book. For the best chance of a lower fare, look to book 86 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.
What is the cheapest month to book a flight from Santiago to San Francisco?
Currently, February is the cheapest month in which you can book a flight from Santiago to San Francisco (average of $633). Flying from Santiago to San Francisco in October is currently the most expensive (average of $911). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Santiago to San Francisco?
Airfare is typical for this route at the moment.
Santiago to San Francisco flights typically cost between $607 and $1,087 in December.The cheapest round-trip price found within the last 5 days was $811 on Avianca (Dec 9-Dec 31).
Reviews of airlines servicing San Francisco
Get insights into the airlines that provide service to San Francisco. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Francisco. Reviews last updated November 7, 2026.
Peruse reviews from past customers who have flown with Delta,Copa Airlines, andLATAM Airlines from Santiago to San Francisco to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Comfort
7.8
Overall
7.8
Entertainment
7.8
Crew
8.5
Food
7.2
Boarding
8.1
Reviews
1 / 20
10.0
ExcellentAaron,Oct 2024
TUS - LAX
Comfort
7.8
Overall
7.8
Entertainment
7.8
Crew
8.5
Food
7.2
Boarding
8.1
Reviews
1 / 20
10.0
ExcellentAaron,Oct 2024
TUS - LAX
Comfort
7.8
Overall
7.8
Entertainment
7.8
Crew
8.5
Food
7.2
Boarding
8.1
Reviews
1 / 20
10.0
ExcellentAaron,Oct 2024
TUS - LAX
Comfort
7.8
Overall
7.8
Entertainment
7.8
Crew
8.5
Food
7.2
Boarding
8.1
Reviews
1 / 20
10.0
ExcellentAaron,Oct 2024
TUS - LAX
Comfort
7.8
Overall
7.8
Entertainment
7.8
Crew
8.5
Food
7.2
Boarding
8.1
Reviews
1 / 20
10.0
ExcellentAaron,Oct 2024
TUS - LAX
Comfort
7.8
Overall
7.8
Entertainment
7.8
Crew
8.5
Food
7.2
Boarding
8.1
Reviews
1 / 20
10.0
ExcellentAaron,Oct 2024
TUS - LAX
Related info for your journey
Find useful and relevant information for your journey from Santiago to San Francisco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near San Francisco?
Book flights to San Francisco if you plan to visit one of these locationsSouth San Francisco
Santa Clara
Santa Cruz
Walnut Creek
Hayward
Emeryville
Newark
Burlingame
San Bruno
Rancho Cordova
Vallejo
Cupertino
Fairfield
Redwood City
San Carlos
Sunnyvale
Turlock
Davis
Morgan Hill
Roseville
Browse thousands of different options on Cheapflights for your next trip
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Santiago and San Francisco flights
Browse other Santiago and San Francisco flight options. Last updated on November 7, 2026.
Other flights from Santiago
Browse through other flights departing from Santiago. Flights are based on user searches made on Cheapflights and were last updated on November 7, 2026.
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Explore flights to San Francisco departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on November 7, 2026.
Top 5 airlines flying from Santiago to San Francisco
Discover the top 5 airlines that operate flights from Santiago to San Francisco. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated November 7, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$311 | Average$757 | FlexibilityNo cancel fee | On-time70% | |
| Cheapest$494 | Average$667 | FlexibilityNo cancel fee | On-time81% | |
| Cheapest$515 | Average$920 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$531 | Average$735 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$542 | Average$638 | FlexibilityNo cancel fee | On-time71% |