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$276+ Cheap flights from Santiago (SCL) to San Francisco (SFO)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/26. Fares are subject to change and may not be available on all flights or dates of travel.
SCL — SFO
Jul 22 — Jul 291
Wed 7/22
Wed 7/29
1 adult, Economy
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Cheap flight deals from Santiago to San Francisco

Cheapest flights from Santiago to San Francisco
Explore the most affordable flight options available from Santiago to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 22, 2026.

This Avianca deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/246:40 am
SCL
-
SFO
2 stops18h 55m
Avianca
Mon 7/272:15 pm
SFO
-
SCL
2 stops21h 00m
Avianca
Deal found 6/18$546
This Cheapflightsfares deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/74:20 pm
SCL
-
SFO
2 stops34h 15m
Avianca
Thu 9/1011:55 pm
SFO
-
SCL
2 stops25h 50m
Avianca
Deal found 6/18$559
This Gotogate deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/2311:22 am
SCL
-
SFO
1 stop33h 38m
Copa Airlines
Tue 8/41:12 am
SFO
-
SCL
1 stop21h 38m
Copa Airlines
Deal found 6/19$561
This Delta deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/1011:00 pm
SCL
-
SFO
2 stops26h 00m
Delta
Mon 8/249:30 am
SFO
-
SCL
1 stop17h 05m
Delta
Deal found 6/19$563
This Copa Airlines deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/1811:22 am
SCL
-
SFO
1 stop33h 37m
Copa Airlines
Sun 8/238:21 pm
SFO
-
SCL
1 stop26h 29m
Copa Airlines
Deal found 6/22$568
This Delta deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/308:40 pm
SCL
-
SFO
1 stop23h 51m
Delta
Thu 8/137:13 am
SFO
-
SCL
2 stops20h 42m
Delta
Deal found 6/17$571
This SmartFares deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure SmartFares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/273:20 pm
SCL
-
SFO
2 stops24h 30m
Avianca
Wed 8/122:15 pm
SFO
-
SCL
2 stops21h 00m
Avianca
Deal found 6/18$572
This SmartFares deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure SmartFares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/233:20 pm
SCL
-
SFO
2 stops24h 30m
Avianca
Tue 8/42:30 am
SFO
-
SCL
2 stops23h 15m
Avianca
Deal found 6/19$573
This oojo deal was found by Cheapflights users on 6/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/186:40 am
SCL
-
SFO
2 stops18h 55m
Avianca
Tue 8/257:45 am
SFO
-
SCL
3 stops36h 35m
Avianca
Deal found 6/21$575
This Delta deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/1411:25 pm
SCL
-
SFO
1 stop16h 29m
Delta
Mon 10/2611:45 pm
SFO
-
SCL
2 stops25h 50m
Delta
Deal found 6/17$576
This FlightHub deal was found by Cheapflights users on 6/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/126:40 am
SCL
-
SFO
2 stops18h 55m
Avianca
Tue 8/187:45 am
SFO
-
SCL
3 stops27h 30m
Avianca
Deal found 6/21$578
This LATAM Airlines deal was found by Cheapflights users on 6/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/68:30 am
SCL
-
SFO
3 stops34h 38m
LATAM Airlines
Wed 10/146:00 am
SFO
-
SCL
3 stops27h 25m
LATAM Airlines
Deal found 6/21$579

Find flight deals from Santiago to San Francisco

Discover tips and strategies to find the most affordable flight options for your journey from Santiago (SCL) to San Francisco (SFO). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated June 22, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$544
(Avianca)

One-way from

$276
(Avianca)

Popular in

June

Cheapest in

October

Average price

$781
Provider with most accurate pricing for Santiago Arturo Merino Benitez-San Francisco flight deals.
Search Deals
Provider most trusted by Cheapflights users for Santiago Arturo Merino Benitez-San Francisco flights.
Search Deals
From Santiago Arturo Merino Benitez to San Francisco
Search Deals
One-way flight from Santiago Arturo Merino Benitez to San Francisco
Search Deals
Highest demand for flights based on searches. 9% potential increase in price ($71 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($12 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in June 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Santiago to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 22, 2026.
Use the filters below to find and compare flights from Santiago to San Francisco that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

SantiagoSan Francisco

SCL - SFO

SCLSFO

Santiago Arturo Merino Benitez

Tue 8/11

11:00 pm-7:39 pm

2 stops23h 39m

San Francisco

Tue 8/25

6:00 am-7:15 am

1 stop22h 15m

$563

SantiagoSan Francisco

SCL - SFO

SCLSFO

Santiago Arturo Merino Benitez

Mon 8/24

12:43 am-6:00 pm

1 stop20h 17m

San Francisco

Sun 9/6

1:12 am-12:22 am

1 stop19h 10m

$568

SantiagoSan Francisco

SCL - SFO

SCLSFO

Santiago Arturo Merino Benitez

Thu 7/30

8:40 pm-5:31 pm

1 stop23h 51m

San Francisco

Thu 8/13

7:13 am-6:55 am

2 stops20h 42m

$571

SantiagoSan Francisco

SCL - SFO

SCLSFO

Santiago Arturo Merino Benitez

Wed 8/5

11:00 pm-5:15 pm

2 stops21h 15m

San Francisco

Tue 8/11

7:13 am-5:35 am

1 stop19h 22m

$571

SantiagoSan Francisco

SCL - SFO

SCLSFO

Santiago Arturo Merino Benitez

Tue 10/13

8:40 pm-10:32 am

1 stop17h 52m

San Francisco

Wed 10/28

11:45 pm-5:35 am

2 stops25h 50m

$576

SantiagoSan Francisco

SCL - SFO

SCLSFO

Santiago Arturo Merino Benitez

Mon 10/12

11:00 pm-9:35 pm

2 stops26h 35m

San Francisco

Sun 10/25

7:00 am-5:35 am

2 stops18h 35m

$576

SantiagoSan Francisco

SCL - SFO

SCLSFO

Santiago Arturo Merino Benitez

Wed 8/19

12:43 am-11:40 pm

1 stop25h 57m

San Francisco

Thu 9/3

1:12 am-2:56 am

1 stop22h 44m

$591

SantiagoSan Francisco

SCL - SFO

SCLSFO

Santiago Arturo Merino Benitez

Tue 8/18

3:20 pm-6:25 am

3 stops42h 05m

San Francisco

Sat 8/22

2:30 am-4:45 am

2 stops23h 15m

$592
Quickest round-trip

SantiagoSan Francisco

SCL - SFO

SCLSFO

Santiago Arturo Merino Benitez

Wed 12/9

11:10 pm-11:59 am

1 stop17h 49m

San Francisco

Sun 1/31

7:30 am-6:40 am

1 stop18h 10m

$594

SantiagoSan Francisco

SCL - SFO

SCLSFO

Santiago Arturo Merino Benitez

Fri 10/23

5:15 am-11:40 pm

1 stop22h 25m

San Francisco

Wed 11/4

12:33 am-3:38 am

1 stop22h 05m

$662

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/19

Showing 1-10 of 18 resultsSorted by cheapest first
1
2

Compare providers for flights from Santiago to San Francisco

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Santiago to San Francisco in June.
ProviderPrice AccuracyTrust Score*
FlightHubPrice Accuracy3 starsTrust Score*3 stars
AranGrantPrice Accuracy3 starsTrust Score*3 stars
Justfly.comPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Santiago-San Francisco flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Santiago-San Francisco flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Santiago-San Francisco flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Santiago-San Francisco flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Santiago-San Francisco flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Santiago to San Francisco

Have a flexible travel schedule? Discover the best time to fly to San Francisco from Santiago with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Santiago to San Francisco

How far ahead should I book a flight from Santiago to San Francisco?

The price you pay for your flight from Santiago to San Francisco may vary depending on when you book. For the best chance of a lower fare, look to book 6 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

What is the cheapest month to book a flight from Santiago to San Francisco?

Currently, October is the cheapest month in which you can book a flight from Santiago to San Francisco (average of $555). Flying from Santiago to San Francisco in June is currently the most expensive (average of $781). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Santiago to San Francisco?

Reviews of airlines servicing San Francisco

Get insights into the airlines that provide service to San Francisco. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Francisco. Reviews last updated June 22, 2026.
Peruse reviews from past customers who have flown with Delta,Copa Airlines, andLATAM Airlines from Santiago to San Francisco to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.8
Good
8,424 reviews

Food

7.2

Boarding

8.1

Overall

7.8

Comfort

7.8

Crew

8.5

Entertainment

7.8

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
Delta
7.8
Good
8,424 reviews
Delta
7.8
Good
8,424 reviews

Food

7.2

Boarding

8.1

Overall

7.8

Comfort

7.8

Crew

8.5

Entertainment

7.8

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
Copa Airlines
7.6
Good
1,568 reviews
Delta
7.8
Good
8,424 reviews

Food

7.2

Boarding

8.1

Overall

7.8

Comfort

7.8

Crew

8.5

Entertainment

7.8

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
LATAM Airlines
7.4
Good
1,942 reviews
Delta
7.8
Good
8,424 reviews

Food

7.2

Boarding

8.1

Overall

7.8

Comfort

7.8

Crew

8.5

Entertainment

7.8

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
American Airlines
7.1
Good
11,741 reviews
Delta
7.8
Good
8,424 reviews

Food

7.2

Boarding

8.1

Overall

7.8

Comfort

7.8

Crew

8.5

Entertainment

7.8

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
Avianca
6.5
Okay
2,533 reviews
Delta
7.8
Good
8,424 reviews

Food

7.2

Boarding

8.1

Overall

7.8

Comfort

7.8

Crew

8.5

Entertainment

7.8

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Related info for your journey

Find useful and relevant information for your journey from Santiago to San Francisco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Santiago to San Francisco?

    Departing from Santiago to San Francisco will take you 20h 17m. The distance from Santiago to San Francisco is about 5918 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines flying from Santiago to San Francisco round-trip?

    Currently priced at $311, Copa Airlines will fly you from Santiago to San Francisco and back. In addition to Copa Airlines, many other airlines offer competitively priced options for your trip. Search Cheapflights for deals from Avianca and American Airlines - these airlines can fly you to your destination from $408 and $481, respectively. Copa Airlines is priced at 52% lower than the current average price of a flight leaving 3 months from now.

  • What are the cheapest airlines to fly from Santiago to San Francisco one-way?

    One-way options have recently been found by users for as low as $277 on Copa Airlines. Other airlines that offer cheap prices include Avianca from $278 and LATAM Airlines from $431 one-way.

  • Can I find deals for flights from Santiago to San Francisco that include hotel bookings?

    Yes. In addition to deals on Santiago to San Francisco flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Santiago to San Francisco?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santiago to San Francisco.

  • Can I find deals for business class flights from Santiago to San Francisco?

    Yes. Cheapflights offers flight deals from Santiago to San Francisco by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Santiago to San Francisco?

    Currently, October is the cheapest month in which you can book a flight from Santiago to San Francisco (average of $555). Flying from Santiago to San Francisco in June is currently the most expensive (average of $781). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near San Francisco?

Book flights to San Francisco if you plan to visit one of these locations
South San Francisco
Santa Clara
Santa Cruz
Fairfield
Burlingame
Rancho Cordova
Roseville
Cupertino
Emeryville
Watsonville
Newark
San Bruno
Hayward
San Ramon
San Carlos
Redwood City
Turlock
Daly City
Sunnyvale
Vallejo

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Santiago to San Francisco

See prices for flight routes from nearby airports that may be better suited for you.
Santiago to Los Angeles flights
Santiago to Las Vegas flights
Santiago to San Diego flights
Santiago to Sacramento flights
Santiago to Oakland flights
Temuco to Los Angeles flights

Top 6 airlines flying from Santiago to San Francisco

Discover the top 6 airlines that operate flights from Santiago to San Francisco. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 22, 2026.
AirlineCheapestAverageFlexibilityOn-time
Copa AirlinesCheapest$311Average$673FlexibilityNo cancel feeOn-time70%
AviancaCheapest$408Average$635FlexibilityNo cancel feeOn-time71%
American AirlinesCheapest$481Average$698FlexibilityNo cancel feeOn-time71%
LATAM AirlinesCheapest$501Average$665FlexibilityNo cancel feeOn-time81%
DeltaCheapest$509Average$744FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$571Average$710FlexibilityNo cancel feeOn-time69%

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