$277+ Cheap flights from Santiago (SCL) to San Francisco (SFO)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/20. Fares are subject to change and may not be available on all flights or dates of travel.
SCL — SFO
Jul 7 — Jul 141
Round-trip
1 adult, Economy
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Cheapest flights from Santiago to San FranciscoExplore the most affordable flight options available from Santiago to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 7, 2026.
Explore the most affordable flight options available from Santiago to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 7, 2026.
This Avianca deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/136:40 am
SCL
- SFO
2 stops20h 15m
Avianca
Mon 6/2211:55 pm
SFO
- SCL
2 stops20h 25m
Avianca
Deal found 6/4![Avianca logo]()
$555
This American Airlines deal was found by Cheapflights users on 6/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/58:50 pm
SCL
- SFO
1 stop16h 44m
American Airlines
Tue 8/115:48 am
SFO
- SCL
2 stops21h 37m
American Airlines
Deal found 6/2![American Airlines logo]()
$556
This Avianca deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/226:40 am
SCL
- SFO
2 stops18h 55m
Avianca
Sun 8/162:15 pm
SFO
- SCL
2 stops21h 00m
Avianca
Deal found 6/3![Avianca logo]()
$557
This CheapOair deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/108:40 pm
SCL
- SFO
1 stop18h 05m
LATAM Airlines
Wed 6/179:20 am
SFO
- SCL
1 stop17h 15m
LATAM Airlines
Deal found 6/3![LATAM Airlines logo]()
$558
This Copa Airlines deal was found by Cheapflights users on 6/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/131:44 am
SCL
- SFO
1 stop25h 56m
Copa Airlines
Thu 10/221:12 am
SFO
- SCL
1 stop24h 58m
Copa Airlines
Deal found 6/2![Copa Airlines logo]()
$561
This Flightnetwork deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Flightnetwork is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/236:40 am
SCL
- SFO
2 stops42h 55m
Avianca
Sat 11/2811:10 pm
SFO
- SCL
2 stops35h 10m
Avianca
Deal found 6/4![Avianca logo]()
$563
This American Airlines deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/99:00 pm
SCL
- SFO
1 stop29h 44m
American Airlines
Tue 6/1611:59 pm
SFO
- SCL
1 stop28h 06m
American Airlines
Deal found 6/3![American Airlines logo]()
$566
This United Airlines deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/259:45 pm
SCL
- SFO
1 stop37h 35m
United Airlines
Mon 12/712:45 am
SFO
- SCL
1 stop27h 05m
United Airlines
Deal found 6/6![United Airlines logo]()
$567
This Copa Airlines deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/112:56 am
SCL
- SFO
1 stop23h 44m
Copa Airlines
Tue 8/188:21 pm
SFO
- SCL
1 stop27h 39m
Copa Airlines
Deal found 6/4![Copa Airlines logo]()
$568
This SmartFares deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure SmartFares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/267:40 am
SCL
- SFO
2 stops18h 55m
Avianca
Mon 11/3011:10 pm
SFO
- SCL
2 stops20h 20m
Avianca
Deal found 6/6![Avianca logo]()
$570
This Delta deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/128:40 pm
SCL
- SFO
1 stop25h 59m
Delta
Wed 8/267:53 am
SFO
- SCL
1 stop20h 22m
Delta
Deal found 6/4![Delta logo]()
$571
This Avianca deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/96:40 am
SCL
- SFO
2 stops20h 15m
Avianca
Tue 6/1611:55 pm
SFO
- SCL
2 stops20h 25m
Avianca
Deal found 6/3![Avianca logo]()
$573
Best flights from Santiago to San FranciscoDiscover carefully curated flight deals from Santiago to San Francisco that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 7, 2026.
Discover carefully curated flight deals from Santiago to San Francisco that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 7, 2026.
This Copa Airlines deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/292:14 am
SCL
- SFO
1 stop24h 26m
Copa Airlines
Thu 8/138:21 pm
SFO
- SCL
1 stop26h 59m
Copa Airlines
Deal found 6/3![Copa Airlines logo]()
$561
This Delta deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/128:40 pm
SCL
- SFO
1 stop25h 59m
Delta
Tue 8/186:00 am
SFO
- SCL
2 stops21h 55m
Delta
Deal found 6/5![Delta logo]()
$571
This LATAM Airlines deal was found by Cheapflights users on 6/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/116:00 pm
SCL
- SFO
2 stops32h 30m
Multiple Airlines
Tue 7/217:00 am
SFO
- SCL
1 stop19h 35m
Multiple Airlines
Deal found 6/2![Multiple Airlines logo]()
$610
This Copa Airlines deal was found by Cheapflights users on 6/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/304:21 am
SCL
- SFO
1 stop22h 19m
Copa Airlines
Fri 8/141:12 am
SFO
- SCL
1 stop19h 14m
Copa Airlines
Deal found 6/2![Copa Airlines logo]()
$561
This Delta deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/2811:00 pm
SCL
- SFO
2 stops21h 31m
Delta
Tue 8/117:13 am
SFO
- SCL
1 stop19h 22m
Delta
Deal found 6/6![Delta logo]()
$571
This LATAM Airlines deal was found by Cheapflights users on 6/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/104:10 am
SCL
- SFO
2 stops20h 56m
Multiple Airlines
Mon 6/2211:59 pm
SFO
- SCL
2 stops26h 36m
Multiple Airlines
Deal found 6/2![Multiple Airlines logo]()
$616
This Copa Airlines deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/112:56 am
SCL
- SFO
1 stop23h 44m
Copa Airlines
Tue 8/188:21 pm
SFO
- SCL
1 stop27h 39m
Copa Airlines
Deal found 6/4![Copa Airlines logo]()
$568
This Delta deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/3111:00 pm
SCL
- SFO
2 stops19h 42m
Delta
Sun 9/67:53 am
SFO
- SCL
2 stops19h 02m
Delta
Deal found 6/5![Delta logo]()
$571
This Copa Airlines deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/2411:22 am
SCL
- SFO
1 stop33h 38m
Copa Airlines
Mon 9/71:12 am
SFO
- SCL
1 stop24h 58m
Copa Airlines
Deal found 6/4![Copa Airlines logo]()
$568
This LATAM Airlines deal was found by Cheapflights users on 6/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/1210:55 pm
SCL
- SFO
1 stop40h 24m
Multiple Airlines
Wed 8/1211:52 pm
SFO
- SCL
1 stop28h 03m
Multiple Airlines
Deal found 6/2![Multiple Airlines logo]()
$639
This Copa Airlines deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/3012:06 am
SCL
- SFO
1 stop26h 34m
Copa Airlines
Sun 9/68:21 pm
SFO
- SCL
1 stop24h 01m
Copa Airlines
Deal found 6/5![Copa Airlines logo]()
$591
Last-minute flights from Santiago to San FranciscoDiscover last-minute flight deals from Santiago to San Francisco. Data last updated June 7, 2026 and is based on user searches.
Discover last-minute flight deals from Santiago to San Francisco. Data last updated June 7, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/99:00 pm
SCL
- SFO
1 stop29h 44m
American Airlines
Tue 6/1611:59 pm
SFO
- SCL
1 stop28h 06m
American Airlines
Deal found 6/3![American Airlines logo]()
$566
This Avianca deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/96:40 am
SCL
- SFO
2 stops20h 15m
Avianca
Tue 6/1611:55 pm
SFO
- SCL
2 stops20h 25m
Avianca
Deal found 6/3![Avianca logo]()
$573
This CheapOair deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/108:40 pm
SCL
- SFO
1 stop18h 05m
LATAM Airlines
Wed 6/179:20 am
SFO
- SCL
1 stop17h 15m
LATAM Airlines
Deal found 6/3![LATAM Airlines logo]()
$558
This Avianca deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/136:40 am
SCL
- SFO
2 stops20h 15m
Avianca
Mon 6/2211:55 pm
SFO
- SCL
2 stops20h 25m
Avianca
Deal found 6/4![Avianca logo]()
$555
This SmartFares deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure SmartFares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/611:25 pm
SCL
- SFO
1 stop19h 19m
LATAM Airlines
Mon 7/1311:38 am
SFO
- SCL
1 stop16h 37m
LATAM Airlines
Deal found 6/3![LATAM Airlines logo]()
$556
This Avianca deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/96:40 am
SCL
- SFO
2 stops18h 55m
Avianca
Tue 7/1411:55 pm
SFO
- SCL
2 stops20h 25m
Avianca
Deal found 6/6![Avianca logo]()
$567
This Avianca deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/226:40 am
SCL
- SFO
2 stops18h 55m
Avianca
Sun 8/162:15 pm
SFO
- SCL
2 stops21h 00m
Avianca
Deal found 6/3![Avianca logo]()
$557
This Flightnetwork deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Flightnetwork is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/236:40 am
SCL
- SFO
2 stops42h 55m
Avianca
Sat 11/2811:10 pm
SFO
- SCL
2 stops35h 10m
Avianca
Deal found 6/4![Avianca logo]()
$563
This Copa Airlines deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/234:21 am
SCL
- SFO
1 stop22h 19m
Copa Airlines
Tue 8/41:12 am
SFO
- SCL
1 stop25h 02m
Copa Airlines
Deal found 6/4![Copa Airlines logo]()
$568
This Copa Airlines deal was found by Cheapflights users on 6/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/304:21 am
SCL
- SFO
1 stop22h 19m
Copa Airlines
Fri 8/141:12 am
SFO
- SCL
1 stop19h 14m
Copa Airlines
Deal found 6/2![Copa Airlines logo]()
$561
This oojo deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/303:20 pm
SCL
- SFO
2 stops24h 30m
Avianca
Thu 8/137:45 am
SFO
- SCL
3 stops27h 30m
Avianca
Deal found 6/6![Avianca logo]()
$574
One-way flights from Santiago to San FranciscoSearch for one-way flight options from Santiago to San Francisco. Find affordable one-way fares based on user searches. Data last updated June 7, 2026.
Search for one-way flight options from Santiago to San Francisco. Find affordable one-way fares based on user searches. Data last updated June 7, 2026.
This Avianca deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/206:40 am
SCL
- SFO
2 stops20h 15m
Avianca
Deal found 6/6![Avianca logo]()
$277
This Avianca deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/266:40 am
SCL
- SFO
2 stops18h 55m
Avianca
Deal found 6/3![Avianca logo]()
$278
This Avianca deal was found by Cheapflights users on 6/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/286:40 am
SCL
- SFO
2 stops18h 55m
Avianca
Deal found 6/2![Avianca logo]()
$279
This Kiwi.com deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/116:40 am
SCL
- SFO
2 stops20h 15m
Avianca
Deal found 6/5![Avianca logo]()
$294
This SmartFares deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure SmartFares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/243:20 pm
SCL
- SFO
2 stops34h 15m
Avianca
Deal found 6/3![Avianca logo]()
$296
This Kiwi.com deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/166:40 am
SCL
- SFO
2 stops18h 55m
Avianca
Deal found 6/5![Avianca logo]()
$298
This oojo deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/163:20 pm
SCL
- SFO
2 stops24h 30m
Avianca
Deal found 6/4![Avianca logo]()
$304
This Justfly.com deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/126:40 am
SCL
- SFO
2 stops44h 15m
Avianca
Deal found 6/4![Avianca logo]()
$306
This Kiwi.com deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/226:40 am
SCL
- SFO
2 stops18h 55m
Avianca
Deal found 6/3![Avianca logo]()
$312
This Kissandfly.com deal was found by Cheapflights users on 6/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kissandfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/106:40 am
SCL
- SFO
2 stops44h 15m
Avianca
Deal found 6/2![Avianca logo]()
$314
This FlightHub deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/146:40 am
SCL
- SFO
3 stops26h 45m
Avianca
Deal found 6/5![Avianca logo]()
$318
This Justfly.com deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/136:40 am
SCL
- SFO
3 stops50h 45m
Avianca
Deal found 6/4![Avianca logo]()
$323
Find flight deals from Santiago to San Francisco
Discover tips and strategies to find the most affordable flight options for your journey from Santiago (SCL) to San Francisco (SFO). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated June 7, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $555 (Avianca) |
One-way from | $277 (Avianca) |
Popular in | June |
Cheapest in | October |
Average price | $796 |
Cheapflights Fare Finder
Customize your flight search to find flights from Santiago to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 7, 2026.
Use the filters below to find and compare flights from Santiago to San Francisco that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
SantiagoSan Francisco
SCL - SFO
SCLSFO
Santiago Arturo Merino Benitez
Wed 7/29
2:14 am-11:40 pm
1 stop24h 26m
San Francisco
Thu 8/13
8:21 pm-2:20 am
1 stop26h 59m
$561
SantiagoSan Francisco
SCL - SFO
SCLSFO
Santiago Arturo Merino Benitez
Thu 7/30
4:21 am-11:40 pm
1 stop22h 19m
San Francisco
Fri 8/14
1:12 am-11:26 pm
1 stop19h 14m
$561
SantiagoSan Francisco
SCL - SFO
SCLSFO
Santiago Arturo Merino Benitez
Tue 8/11
2:56 am-11:40 pm
1 stop23h 44m
San Francisco
Tue 8/18
8:21 pm-3:00 am
1 stop27h 39m
$568
SantiagoSan Francisco
SCL - SFO
SCLSFO
Santiago Arturo Merino Benitez
Mon 8/24
11:22 am-6:00 pm
1 stop33h 38m
San Francisco
Mon 9/7
1:12 am-6:10 am
1 stop24h 58m
$568
SantiagoSan Francisco
SCL - SFO
SCLSFO
Santiago Arturo Merino Benitez
Wed 8/12
8:40 pm-7:39 pm
1 stop25h 59m
San Francisco
Tue 8/18
6:00 am-6:55 am
2 stops21h 55m
$571
SantiagoSan Francisco
SCL - SFO
SCLSFO
Santiago Arturo Merino Benitez
Tue 7/28
11:00 pm-5:31 pm
2 stops21h 31m
San Francisco
Tue 8/11
7:13 am-5:35 am
1 stop19h 22m
$571
Quickest round-trip
SantiagoSan Francisco
SCL - SFO
SCLSFO
Santiago Arturo Merino Benitez
Mon 8/31
11:00 pm-3:42 pm
2 stops19h 42m
San Francisco
Sun 9/6
7:53 am-6:55 am
2 stops19h 02m
$571
SantiagoSan Francisco
SCL - SFO
SCLSFO
Santiago Arturo Merino Benitez
Sun 8/30
12:06 am-11:40 pm
1 stop26h 34m
San Francisco
Sun 9/6
8:21 pm-12:22 am
1 stop24h 01m
$591
SantiagoSan Francisco
SCL - SFO
SCLSFO
Santiago Arturo Merino Benitez
Sat 7/11
6:00 pm-11:30 pm
2 stops32h 30m
San Francisco
Tue 7/21
7:00 am-5:35 am
1 stop19h 35m
$610
SantiagoSan Francisco
SCL - SFO
SCLSFO
Santiago Arturo Merino Benitez
Wed 6/10
4:10 am-10:06 pm
2 stops20h 56m
San Francisco
Mon 6/22
11:59 pm-5:35 am
2 stops26h 36m
$616
Showing 1-10 of 21 resultsSorted by cheapest first
Compare providers for flights from Santiago to San Francisco
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Santiago to San Francisco in June.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Santiago-San Francisco flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Santiago-San Francisco flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Santiago-San Francisco flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Santiago-San Francisco flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Santiago-San Francisco flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Santiago to San Francisco
Have a flexible travel schedule? Discover the best time to fly to San Francisco from Santiago with our price prediction graph.
SCL-SFO
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Santiago to San Francisco
How far ahead should I book a flight from Santiago to San Francisco?
The price you pay for your flight from Santiago to San Francisco may vary depending on when you book. For the best chance of a lower fare, look to book 69 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.
What is the cheapest month to book a flight from Santiago to San Francisco?
Currently, October is the cheapest month in which you can book a flight from Santiago to San Francisco (average of $554). Flying from Santiago to San Francisco in June is currently the most expensive (average of $796). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Santiago to San Francisco?
Reviews of airlines servicing San Francisco
Get insights into the airlines that provide service to San Francisco. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Francisco. Reviews last updated June 7, 2026.
Peruse reviews from past customers who have flown with Delta,Copa Airlines, andLATAM Airlines from Santiago to San Francisco to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Food
7.2
Entertainment
7.8
Overall
7.9
Boarding
8.1
Comfort
7.8
Crew
8.5
Reviews
1 / 20
10.0
ExcellentAaron,Oct 2024
TUS - LAX
Food
7.2
Entertainment
7.8
Overall
7.9
Boarding
8.1
Comfort
7.8
Crew
8.5
Reviews
1 / 20
10.0
ExcellentAaron,Oct 2024
TUS - LAX
Food
7.2
Entertainment
7.8
Overall
7.9
Boarding
8.1
Comfort
7.8
Crew
8.5
Reviews
1 / 20
10.0
ExcellentAaron,Oct 2024
TUS - LAX
Food
7.2
Entertainment
7.8
Overall
7.9
Boarding
8.1
Comfort
7.8
Crew
8.5
Reviews
1 / 20
10.0
ExcellentAaron,Oct 2024
TUS - LAX
Food
7.2
Entertainment
7.8
Overall
7.9
Boarding
8.1
Comfort
7.8
Crew
8.5
Reviews
1 / 20
10.0
ExcellentAaron,Oct 2024
TUS - LAX
Food
7.2
Entertainment
7.8
Overall
7.9
Boarding
8.1
Comfort
7.8
Crew
8.5
Reviews
1 / 20
10.0
ExcellentAaron,Oct 2024
TUS - LAX
Related info for your journey
Find useful and relevant information for your journey from Santiago to San Francisco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near San Francisco?
Book flights to San Francisco if you plan to visit one of these locationsSouth San Francisco
Santa Cruz
Santa Clara
Fairfield
Rancho Cordova
Cupertino
Emeryville
Newark
Watsonville
San Bruno
San Ramon
Vacaville
Roseville
San Carlos
Redwood City
Daly City
Turlock
Sunnyvale
Vallejo
San Lorenzo
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
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Alternative routes for Santiago to San Francisco
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Complete your trip
Complete your trip to San Francisco by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Santiago to San Francisco by cabin class
Find flights from Santiago to San Francisco, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Santiago and San Francisco flights
Browse other Santiago and San Francisco flight options. Last updated on June 7, 2026.
Other flights from Santiago
Browse through other flights departing from Santiago. Flights are based on user searches made on Cheapflights and were last updated on June 7, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Other flights to San Francisco
Explore flights to San Francisco departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on June 7, 2026.
Top 6 airlines flying from Santiago to San Francisco
Discover the top 6 airlines that operate flights from Santiago to San Francisco. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 7, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$433 | Average$635 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$481 | Average$698 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$501 | Average$663 | FlexibilityNo cancel fee | On-time81% | |
| Cheapest$511 | Average$757 | FlexibilityNo cancel fee | On-time70% | |
| Cheapest$559 | Average$744 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$571 | Average$710 | FlexibilityNo cancel fee | On-time69% |