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$331+ Cheap flights from Santiago (SCL) to San Francisco (SFO)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/5. Fares are subject to change and may not be available on all flights or dates of travel.
SCL — SFO
May 4 — May 111
Sun 5/4
Sun 5/11
1 adult, Economy
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Cheapflights Tip: The best prices from Santiago Arturo Merino Benitez to San Francisco are usually found in March or November, booked 76 days in advance, depart on a Saturday or Thursday and return on a Wednesday

Cheap flight deals from Santiago to San Francisco

Discover tips and strategies to find the most affordable flight options for your journey from Santiago (SCL) to San Francisco (SFO). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated April 29, 2025.

Most accurate provider

AranGrant
3 stars

Most trusted provider

AranGrant
3 stars

Round-trip from

$557
(Booking.com)

One-way from

$331
(Copa Airlines)

Popular in

June

Cheapest in

March

Average price

$749
Provider with most accurate pricing for Santiago Arturo Merino Benitez-San Francisco flight deals.
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Provider most trusted by Cheapflights users for Santiago Arturo Merino Benitez-San Francisco flights.
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From Santiago Arturo Merino Benitez to San Francisco
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One-way flight from Santiago Arturo Merino Benitez to San Francisco
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Highest demand for flights based on searches. 8% potential increase in price ($69 potential increase over avg. RT price).
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Cheapest flight prices on average. 1% potential price decrease ($13 potential savings vs. average RT price).
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Average for round-trip flights in April 2025
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Find flight deals from Santiago to San Francisco

Cheapest flights from Santiago to San Francisco
Explore the most affordable flight options available from Santiago to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 29, 2025.

This Booking.com deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/1412:55 amSCL - SFO
2 stops25h 50mAvianca
Tue 10/212:20 pmSFO - SCL
2 stops29h 10mAvianca
Deal found 4/28$557
This United Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/610:45 pmSCL - SFO
1 stop25h 10mUnited Airlines
Sun 11/1611:55 pmSFO - SCL
1 stop27h 55mUnited Airlines
Deal found 4/28$559
This American Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/299:50 pmSCL - SFO
1 stop28h 00mAmerican Airlines
Wed 10/296:08 amSFO - SCL
1 stop21h 42mAmerican Airlines
Deal found 4/28$564
This LATAM Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/2511:00 amSCL - SFO
2 stops30h 52mLATAM Airlines
Wed 7/97:30 amSFO - SCL
1 stop20h 30mLATAM Airlines
Deal found 4/28$573
This Copa Airlines deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/202:23 amSCL - SFO
1 stop24h 17mCopa Airlines
Wed 9/31:28 amSFO - SCL
1 stop18h 36mCopa Airlines
Deal found 4/27$577
This Delta deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/1911:05 pmSCL - SFO
2 stops21h 14mDelta
Fri 8/296:00 amSFO - SCL
2 stops21h 30mDelta
Deal found 4/28$580
This eDestinos deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/158:20 amSCL - SFO
1 stop17h 59mMultiple Airlines
Wed 8/276:00 amSFO - SCL
2 stops19h 45mMultiple Airlines
Deal found 4/28$584

Cheapflights Fare Finder

Customize your flight search to find flights from Santiago to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 29, 2025.
Use the filters below to find and compare flights from Santiago to San Francisco that are best for you.

Fly from

Santiago

Fly to

San Francisco

Route

Depart

Return

Price

SantiagoSan Francisco

SCL - SFO

SCLSFO

Santiago Arturo Merino Benitez

Tue 10/14

12:55 am-10:45 pm

2 stops25h 50m

San Francisco

Tue 10/21

2:20 pm-11:30 pm

2 stops29h 10m

$557

SantiagoSan Francisco

SCL - SFO

SCLSFO

Santiago Arturo Merino Benitez

Tue 7/29

9:50 pm-10:50 pm

1 stop28h 00m

San Francisco

Wed 10/29

6:08 am-7:50 am

1 stop21h 42m

$564

SantiagoSan Francisco

SCL - SFO

SCLSFO

Santiago Arturo Merino Benitez

Wed 6/25

11:00 am-2:52 pm

2 stops30h 52m

San Francisco

Wed 7/9

7:30 am-7:00 am

1 stop20h 30m

$573

SantiagoSan Francisco

SCL - SFO

SCLSFO

Santiago Arturo Merino Benitez

Wed 8/20

2:23 am-11:40 pm

1 stop24h 17m

San Francisco

Wed 9/3

1:28 am-11:04 pm

1 stop18h 36m

$577

SantiagoSan Francisco

SCL - SFO

SCLSFO

Santiago Arturo Merino Benitez

Tue 8/19

11:05 pm-5:19 pm

2 stops21h 14m

San Francisco

Fri 8/29

6:00 am-6:30 am

2 stops21h 30m

$580

SantiagoSan Francisco

SCL - SFO

SCLSFO

Santiago Arturo Merino Benitez

Tue 7/15

8:20 am-11:19 pm

1 stop17h 59m

San Francisco

Wed 8/27

6:00 am-4:45 am

2 stops19h 45m

$584

SantiagoSan Francisco

SCL - SFO

SCLSFO

Santiago Arturo Merino Benitez

Mon 5/5

12:13 am-11:40 pm

1 stop26h 27m

$331

SantiagoSan Francisco

SCL - SFO

SCLSFO

Santiago Arturo Merino Benitez

Sun 5/25

11:55 pm-11:55 pm

2 stops51h 00m

$340

SantiagoSan Francisco

SCL - SFO

SCLSFO

Santiago Arturo Merino Benitez

Fri 5/30

2:30 pm-10:23 pm

3 stops34h 53m

$398

SantiagoSan Francisco

SCL - SFO

SCLSFO

Santiago Arturo Merino Benitez

Sun 9/7

11:05 pm-10:00 am

1 stop14h 55m

$439

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/28

Showing 1-10 of 12 results
1
2

Compare providers for flights from Santiago to San Francisco

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Santiago to San Francisco in April.
ProviderPrice AccuracyTrust Score*
FlightHubPrice Accuracy3 starsTrust Score*2 stars
eDreamsPrice Accuracy3 starsTrust Score*3 stars
AranGrantPrice Accuracy3 starsTrust Score*3 stars
CheapflightsfaresPrice Accuracy3 starsTrust Score*2 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Santiago-San Francisco flights, users find the pricing of AranGrant to be most consistent on Cheapflights vs. AranGrant Users can find the same prices on Santiago-San Francisco flight deals on Cheapflights vs. AranGrant >95% of the time. Price accuracy is based on data collected from Santiago-San Francisco flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Santiago-San Francisco flights, Cheapflights users trust AranGrant the most. AranGrant has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Santiago-San Francisco flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Santiago to San Francisco

Have a flexible travel schedule? Discover the best time to fly to San Francisco from Santiago with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Santiago to San Francisco

How far ahead should I book a flight from Santiago to San Francisco?

Use this chart to determine the optimal time to book a round-trip flight from Santiago to San Francisco. Price data was last updated on April 25, 2025.

The price you pay for your flight from Santiago to San Francisco may vary depending on when you book. For the best chance of a lower fare, look to book 75 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

What is the cheapest month to book a flight from Santiago to San Francisco?

Currently, January is the cheapest month in which you can book a flight from Santiago to San Francisco (average of $276). Flying from Santiago to San Francisco in June is currently the most expensive (average of $393). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SCL to SFO?

Find hourly flight availability from Santiago to San Francisco. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 29, 2025.

It’s typically best to fly out from Santiago to San Francisco in the afternoon. Doing so could potentially save you 32% on the flight price compared to flying in the evening, which is usually more expensive.

Rainfall in San Francisco by month

Plan your trip to San Francisco by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in San Francisco ranges from 0.0 - 4.4 inches per month. January is typically the wettest month, when rainfall can reach 4.4 in. July is typically the driest time to visit San Francisco when rainfall is around 0.0 in.

Temperature in San Francisco by month

Plan your trip to San Francisco by taking into account the average temperature totals by month.

If weather is an important factor for your trip to San Francisco, use this chart to help with planning. For those seeking warmer temperatures, September is the ideal time of year to visit, when temperatures reach an average of 62.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 51.8 F).

Reviews of airlines servicing San Francisco

Get insights into the airlines that provide service to San Francisco. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Francisco. Reviews last updated April 29, 2025.
Read through reviews of airlines operating flights from Santiago to San Francisco, such as Delta, LATAM Airlines and Copa Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,929 reviews

Crew

8.5

Entertainment

7.9

Comfort

7.9

Boarding

8.2

Food

7.3

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
Delta
8.0
Very good
7,929 reviews
Delta
8.0
Very good
7,929 reviews

Crew

8.5

Entertainment

7.9

Comfort

7.9

Boarding

8.2

Food

7.3

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
LATAM Airlines
7.5
Good
1,766 reviews
Delta
8.0
Very good
7,929 reviews

Crew

8.5

Entertainment

7.9

Comfort

7.9

Boarding

8.2

Food

7.3

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
Copa Airlines
7.5
Good
1,410 reviews
Delta
8.0
Very good
7,929 reviews

Crew

8.5

Entertainment

7.9

Comfort

7.9

Boarding

8.2

Food

7.3

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,929 reviews

Crew

8.5

Entertainment

7.9

Comfort

7.9

Boarding

8.2

Food

7.3

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
Avianca
6.7
Okay
2,317 reviews
Delta
8.0
Very good
7,929 reviews

Crew

8.5

Entertainment

7.9

Comfort

7.9

Boarding

8.2

Food

7.3

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Related info for your journey

Find useful and relevant information for your journey from Santiago to San Francisco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines flying from Santiago to San Francisco round-trip?

    Currently priced at $557, Avianca will fly you from Santiago to San Francisco and back. In addition to Avianca, many other airlines offer competitively priced options for your trip. Search Cheapflights for deals from American Airlines and LATAM Airlines - these airlines can fly you to your destination from $564 and $573, respectively. Avianca is priced at 20% lower than the current average price of a flight leaving 3 months from now.

  • What are the cheapest airlines to fly from Santiago to San Francisco one-way?

    One-way options have recently been found by users for as low as $331 on Copa Airlines. Other airlines that offer cheap prices include Avianca from $340 and LATAM Airlines from $439 one-way.

  • Can I find deals for flights from Santiago to San Francisco that include hotel bookings?

    Yes. In addition to deals on Santiago to San Francisco flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Santiago to San Francisco?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santiago to San Francisco.

  • Can I find deals for business class flights from Santiago to San Francisco?

    Yes. Cheapflights offers flight deals from Santiago to San Francisco by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Santiago to San Francisco?

    Currently, January is the cheapest month in which you can book a flight from Santiago to San Francisco (average of $276). Flying from Santiago to San Francisco in June is currently the most expensive (average of $393). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Santiago?

Book flights to Santiago if you plan to visit one of these locations
Roseville
Mountain View
Santa Cruz
Turlock
Livermore
South San Francisco
Fairfield
Manteca
Richmond
Watsonville
Hollister
Milpitas
Antioch
Sausalito
Vallejo
Newark
Hayward
Alameda
Sunnyvale
Campbell

Browse thousands of different options on Cheapflights for your next trip

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Top 6 airlines flying from Santiago to San Francisco

Discover the top 6 airlines that operate flights from Santiago to San Francisco. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 29, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$513Average$872FlexibilityNo cancel feeOn-time69%
Copa AirlinesCheapest$518Average$653FlexibilityNo cancel feeOn-time70%
AviancaCheapest$525Average$733FlexibilityNo cancel feeOn-time71%
DeltaCheapest$533Average$714FlexibilityNo cancel feeOn-timeN/A
LATAM AirlinesCheapest$542Average$725FlexibilityNo cancel feeOn-time81%
American AirlinesCheapest$611Average$884FlexibilityNo cancel feeOn-time71%

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