How long is the flight from Santiago to San Francisco?

Departing from Santiago to San Francisco will take you 23h 26m. The distance from Santiago to San Francisco is about 5918 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

What are the cheapest airlines flying from Santiago to San Francisco round-trip?

Currently priced at $408, Avianca will fly you from Santiago to San Francisco and back. In addition to Avianca, many other airlines offer competitively priced options for your trip. Search Cheapflights for deals from American Airlines and LATAM Airlines - these airlines can fly you to your destination from $481 and $508, respectively. Avianca is priced at 37% lower than the current average price of a flight leaving 3 months from now.

What are the cheapest airlines to fly from Santiago to San Francisco one-way?

One-way options have recently been found by users for as low as $267 on Avianca. Other airlines that offer cheap prices include Copa Airlines from $320 and LATAM Airlines from $431 one-way.

In terms of precipitation, rainfall in San Francisco ranges from 0.0 - 4.4 inches per month. January is typically the wettest month, when rainfall can reach 4.4 in. July is typically the driest time to visit San Francisco when rainfall is around 0.0 in.

If weather is an important factor for your trip to San Francisco, use this chart to help with planning. For those seeking warmer temperatures, September is the ideal time of year to visit, when temperatures reach an average of 62.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 51.8 F).

What are the most popular airlines that fly from Santiago to San Francisco?

When booking a flight from Santiago to San Francisco, you may want to consider flying on LATAM Airlines, Delta or Copa Airlines as they are the most popular for this route.

What is the cheapest time of day to fly from SCL to SFO?

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Santiago to San Francisco as you normally would.

Most accurate provider : When it comes to deals on Santiago-San Francisco flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Santiago-San Francisco flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Santiago-San Francisco flight searches over the past month and is updated monthly.

Most trusted provider : When it comes to deals on Santiago-San Francisco flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Santiago-San Francisco flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Can I find deals for flights from Santiago to San Francisco that include hotel bookings?

Yes. In addition to deals on Santiago to San Francisco flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Santiago to San Francisco?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santiago to San Francisco.

Can I find deals for business class flights from Santiago to San Francisco?

Yes. Cheapflights offers flight deals from Santiago to San Francisco by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$457+ Flights from Santiago to San Francisco

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Cheap flight deals from Santiago to San Francisco

Cheapest flights from Santiago to San Francisco
Explore the most affordable flight options available from Santiago to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 30, 2025.

Sun 12/2810:45 pmSCL - SFO

1 stop27h 26mUnited Airlines

Fri 1/1611:59 pmSFO - SCL

1 stop27h 51mUnited Airlines

Deal found 12/28

$608

Mon 12/2911:10 pmSCL - SFO

1 stop26h 40mDelta

Wed 1/146:10 amSFO - SCL

2 stops18h 25mDelta

Deal found 12/27

$695

Sun 12/289:30 pmSCL - SFO

1 stop18h 13mLATAM Airlines

Fri 1/168:00 amSFO - SCL

1 stop17h 10mLATAM Airlines

Deal found 12/27

$704

Mon 12/298:15 amSCL - SFO

3 stops55h 27mLATAM Airlines

Wed 1/148:00 amSFO - SCL

1 stop17h 10mLATAM Airlines

Deal found 12/27

$837

Mon 12/298:15 amSCL - SFO

3 stops44h 48mMultiple Airlines

Wed 1/148:25 amSFO - SCL

2 stops49h 55mMultiple Airlines

Deal found 12/27

$1,294

Sun 12/2811:25 pmSCL - SFO

1 stop17h 21mAeromexico

Fri 1/1610:30 pmSFO - SCL

1 stop17h 45mAeromexico

Deal found 12/28

$1,572

Sun 12/284:25 pmSCL - SFO

2 stops23h 29mMultiple Airlines

Fri 1/162:30 pmSFO - SCL

3 stops35h 20mMultiple Airlines

Deal found 12/27

$2,102

Best flights from Santiago to San Francisco
Discover carefully curated flight deals from Santiago to San Francisco that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated December 30, 2025.

Thu 3/2611:55 pmSCL - SFO

1 stop16h 12mMultiple Airlines

Sun 4/125:43 pmSFO - SCL

2 stops17h 02mMultiple Airlines

Deal found 12/29

$528

Tue 3/104:25 pmSCL - SFO

2 stops24h 35mAvianca

Thu 6/42:30 amSFO - SCL

2 stops22h 45mAvianca

Deal found 12/28

$529

Fri 3/1310:10 pmSCL - SFO

1 stop23h 26mLATAM Airlines

Tue 3/178:55 amSFO - SCL

1 stop16h 40mLATAM Airlines

Deal found 12/29

$534

Thu 4/97:05 amSCL - SFO

2 stops20h 17mDelta

Wed 4/156:00 amSFO - SCL

1 stop22h 15mDelta

Deal found 12/28

$540

Mon 3/1612:20 amSCL - SFO

2 stops27h 01mLATAM Airlines

Wed 4/111:35 pmSFO - SCL

2 stops27h 25mLATAM Airlines

Deal found 12/27

$534

Fri 4/107:05 amSCL - SFO

2 stops19h 11mDelta

Thu 4/166:00 amSFO - SCL

2 stops21h 55mDelta

Deal found 12/28

$540

Thu 3/196:40 amSCL - SFO

2 stops21h 42mLATAM Airlines

Tue 3/316:00 amSFO - SCL

2 stops22h 15mLATAM Airlines

Deal found 12/27

$539

Mon 4/611:00 pmSCL - SFO

2 stops23h 19mDelta

Thu 4/167:00 amSFO - SCL

1 stop20h 50mDelta

Deal found 12/28

$540

Wed 4/87:45 amSCL - SFO

2 stops19h 39mDelta

Thu 4/166:00 amSFO - SCL

2 stops21h 55mDelta

Deal found 12/28

$540

Last-minute flights from Santiago to San Francisco
Discover last-minute flight deals from Santiago to San Francisco. Data last updated December 30, 2025 and is based on user searches.

Mon 12/2911:10 pmSCL - SFO

1 stop26h 40mDelta

Wed 1/146:10 amSFO - SCL

2 stops18h 25mDelta

Deal found 12/27

$695

Tue 1/2011:10 pmSCL - SFO

1 stop26h 15mDelta

Sun 1/256:00 amSFO - SCL

1 stop19h 10mDelta

Deal found 12/29

$690

Wed 1/214:25 pmSCL - SFO

2 stops35h 55mAvianca

Thu 3/192:35 amSFO - SCL

2 stops22h 55mAvianca

Deal found 12/28

$598

Wed 1/214:25 pmSCL - SFO

2 stops35h 55mAvianca

Thu 1/291:20 pmSFO - SCL

2 stops21h 00mAvianca

Deal found 12/28

$623

Thu 1/227:25 amSCL - SFO

2 stops20h 55mAvianca

Thu 1/291:20 pmSFO - SCL

2 stops21h 00mAvianca

Deal found 12/28

$565

Thu 1/2211:55 pmSCL - SFO

1 stop26h 31mAmerican Airlines

Thu 1/2911:55 amSFO - SCL

1 stop15h 20mAmerican Airlines

Deal found 12/28

$589

Tue 1/274:25 pmSCL - SFO

2 stops24h 35mAvianca

Tue 2/241:20 pmSFO - SCL

2 stops21h 00mAvianca

Deal found 12/29

$611

Tue 1/2710:30 pmSCL - SFO

1 stop20h 16mAmerican Airlines

Sat 2/2811:35 pmSFO - SCL

1 stop27h 30mAmerican Airlines

Deal found 12/28

$629

Tue 1/274:25 pmSCL - SFO

2 stops24h 35mAvianca

Sat 2/2811:10 pmSFO - SCL

2 stops20h 20mAvianca

Deal found 12/28

$689

Thu 1/2910:30 pmSCL - SFO

2 stops21h 35mAmerican Airlines

Tue 3/36:00 amSFO - SCL

2 stops21h 05mAmerican Airlines

Deal found 12/28

$539

One-way flights from Santiago to San Francisco
Search for one-way flight options from Santiago to San Francisco. Find affordable one-way fares based on user searches. Data last updated December 30, 2025.

Fri 1/236:40 amSCL - SFO

2 stops21h 14mLATAM Airlines

Deal found 12/29

$457

Mon 2/166:30 pmSCL - SFO

3 stops32h 09mMultiple Airlines

Deal found 12/29

$459

Thu 3/268:20 amSCL - SFO

3 stops32h 46mDelta

Deal found 12/28

$462

Thu 4/911:55 pmSCL - SFO

3 stops34h 58mMultiple Airlines

Deal found 12/28

$466

Mon 3/309:40 amSCL - SFO

3 stops38h 53mLATAM Airlines

Deal found 12/28

$467

Sat 3/289:15 pmSCL - SFO

3 stops46h 11mMultiple Airlines

Deal found 12/28

$471

Tue 3/313:30 pmSCL - SFO

3 stops25h 05mAvianca

Deal found 12/28

$474

Wed 3/111:38 amSCL - SFO

3 stops23h 26mMultiple Airlines

Deal found 12/27

$494

Tue 3/241:38 amSCL - SFO

3 stops23h 26mMultiple Airlines

Deal found 12/28

$495

Tue 2/247:15 amSCL - SFO

3 stops32h 34mLATAM Airlines

Deal found 12/28

$496

Tue 3/101:38 amSCL - SFO

3 stops23h 26mMultiple Airlines

Deal found 12/27

$512

Find flight deals from Santiago to San Francisco

Most accurate provider	eDreams 3 stars
Most trusted provider	eDreams 3 stars
Round-trip from	$528 (SmartFares)
One-way from	$457 (eDestinos)
Popular in	June
Cheapest in	October
Average price	$664

Provider with most accurate pricing for Santiago Arturo Merino Benitez-San Francisco flight deals.

Search Deals

Provider most trusted by Cheapflights users for Santiago Arturo Merino Benitez-San Francisco flights.

Search Deals

From Santiago Arturo Merino Benitez to San Francisco

Search Deals

One-way flight from Santiago Arturo Merino Benitez to San Francisco

Search Deals

Highest demand for flights based on searches. 9% potential increase in price ($67 potential increase over avg. RT price).

Search Deals

Cheapest flight prices on average. 1% potential price decrease ($11 potential savings vs. average RT price).

Search Deals

Average for round-trip flights in December 2025

Search Deals

Cheapflights Fare Finder

Use the filters below to find and compare flights from Santiago to San Francisco that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

SantiagoSan Francisco

SCL - SFO

SCLSFO

Santiago Arturo Merino Benitez

Thu 3/26

11:55 pm-12:07 pm

1 stop16h 12m

San Francisco

Sun 4/12

5:43 pm-1:45 pm

2 stops17h 02m

$528

SantiagoSan Francisco

SCL - SFO

SCLSFO

Santiago Arturo Merino Benitez

Tue 3/10

4:25 pm-1:00 pm

2 stops24h 35m

San Francisco

Thu 6/4

2:30 am-4:15 am

2 stops22h 45m

$529

SantiagoSan Francisco

SCL - SFO

SCLSFO

Santiago Arturo Merino Benitez

Fri 3/13

10:10 pm-5:36 pm

1 stop23h 26m

San Francisco

Tue 3/17

8:55 am-5:35 am

1 stop16h 40m

$534

SantiagoSan Francisco

SCL - SFO

SCLSFO

Santiago Arturo Merino Benitez

Mon 3/16

12:20 am-11:21 pm

2 stops27h 01m

San Francisco

Wed 4/1

11:35 pm-7:00 am

2 stops27h 25m

$534

SantiagoSan Francisco

SCL - SFO

SCLSFO

Santiago Arturo Merino Benitez

Thu 3/19

6:40 am-12:22 am

2 stops21h 42m

San Francisco

Tue 3/31

6:00 am-8:15 am

2 stops22h 15m

$539

SantiagoSan Francisco

SCL - SFO

SCLSFO

Santiago Arturo Merino Benitez

Thu 4/9

7:05 am-12:22 am

2 stops20h 17m

San Francisco

Wed 4/15

6:00 am-7:15 am

1 stop22h 15m

$540

SantiagoSan Francisco

SCL - SFO

SCLSFO

Santiago Arturo Merino Benitez

Fri 4/10

7:05 am-11:16 pm

2 stops19h 11m

San Francisco

Thu 4/16

6:00 am-6:55 am

2 stops21h 55m

$540

SantiagoSan Francisco

SCL - SFO

SCLSFO

Santiago Arturo Merino Benitez

Mon 4/6

11:00 pm-7:19 pm

2 stops23h 19m

San Francisco

Thu 4/16

7:00 am-6:50 am

1 stop20h 50m

$540

SantiagoSan Francisco

SCL - SFO

SCLSFO

Santiago Arturo Merino Benitez

Wed 4/8

7:45 am-12:24 am

2 stops19h 39m

San Francisco

Thu 4/16

6:00 am-6:55 am

2 stops21h 55m

$540

SantiagoSan Francisco

SCL - SFO

SCLSFO

Santiago Arturo Merino Benitez

Sat 2/28

11:15 pm-11:00 pm

1 stop28h 45m

$457

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/28

Showing 1-10 of 19 results

Compare providers for flights from Santiago to San Francisco

Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Santiago to San Francisco in December.

Provider	Price Accuracy	Trust Score*
eDreams	Price Accuracy3 stars	Trust Score*3 stars
FlightHub	Price Accuracy3 stars	Trust Score*1 star
AranGrant	Price Accuracy2 stars	Trust Score*3 stars
Justfly.com	Price Accuracy3 stars	Trust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

Most accurate provider: When it comes to deals on Santiago-San Francisco flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Santiago-San Francisco flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Santiago-San Francisco flight searches over the past month and is updated monthly.
Most trusted provider: When it comes to deals on Santiago-San Francisco flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Santiago-San Francisco flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Santiago to San Francisco

Have a flexible travel schedule? Discover the best time to fly to San Francisco from Santiago with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Santiago to San Francisco

How far ahead should I book a flight from Santiago to San Francisco?

The price you pay for your flight from Santiago to San Francisco may vary depending on when you book. For the best chance of a lower fare, look to book 76 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

What is the cheapest month to book a flight from Santiago to San Francisco?

Currently, February is the cheapest month in which you can book a flight from Santiago to San Francisco (average of $427). Flying from Santiago to San Francisco in April is currently the most expensive (average of $555). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing San Francisco

Peruse reviews from past customers who have flown with Delta, Copa Airlines, and LATAM Airlines from Santiago to San Francisco to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.

Delta

7.9

Good

8,017 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Delta

7.9

Good

8,017 reviews

Delta

7.9

Good

8,017 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Copa Airlines

7.6

Good

1,565 reviews

Delta

7.9

Good

8,017 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

LATAM Airlines

7.5

Good

1,896 reviews

Delta

7.9

Good

8,017 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

American Airlines

7.2

Good

11,073 reviews

Delta

7.9

Good

8,017 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Avianca

6.6

Okay

2,491 reviews

Delta

7.9

Good

8,017 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Related info for your journey

How long is the flight from Santiago to San Francisco?
Departing from Santiago to San Francisco will take you 23h 26m. The distance from Santiago to San Francisco is about 5918 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.
What are the cheapest airlines flying from Santiago to San Francisco round-trip?
Currently priced at $408, Avianca will fly you from Santiago to San Francisco and back. In addition to Avianca, many other airlines offer competitively priced options for your trip. Search Cheapflights for deals from American Airlines and LATAM Airlines - these airlines can fly you to your destination from $481 and $508, respectively. Avianca is priced at 37% lower than the current average price of a flight leaving 3 months from now.
What are the cheapest airlines to fly from Santiago to San Francisco one-way?
One-way options have recently been found by users for as low as $267 on Avianca. Other airlines that offer cheap prices include Copa Airlines from $320 and LATAM Airlines from $431 one-way.
Can I find deals for flights from Santiago to San Francisco that include hotel bookings?
Yes. In addition to deals on Santiago to San Francisco flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Santiago to San Francisco?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santiago to San Francisco.
Can I find deals for business class flights from Santiago to San Francisco?
Yes. Cheapflights offers flight deals from Santiago to San Francisco by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Santiago to San Francisco?
Currently, February is the cheapest month in which you can book a flight from Santiago to San Francisco (average of $427). Flying from Santiago to San Francisco in April is currently the most expensive (average of $555). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Roseville

South San Francisco

Santa Cruz

Livermore

Santa Clara

Watsonville

Redwood City

Sunnyvale

San Bruno

Daly City

Manteca

Turlock

San Carlos

Vallejo

Hollister

San Ramon

Foster City

Union City

Davis

Emeryville

Browse thousands of different options on Cheapflights for your next trip

Top 6 airlines flying from Santiago to San Francisco

Airline	Cheapest	Average	Flexibility	On-time
Avianca	Cheapest$408	Average$710	FlexibilityNo cancel fee	On-time71%
American Airlines	Cheapest$481	Average$613	FlexibilityNo cancel fee	On-time71%
Copa Airlines	Cheapest$511	Average$627	FlexibilityNo cancel fee	On-time70%
LATAM Airlines	Cheapest$518	Average$706	FlexibilityNo cancel fee	On-time81%
Delta	Cheapest$554	Average$743	FlexibilityNo cancel fee	On-timeN/A
United Airlines	Cheapest$571	Average$720	FlexibilityNo cancel fee	On-time69%

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$457+ Cheap flights from Santiago (SCL) to San Francisco (SFO)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/23. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Santiago to San Francisco with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Cheap flight deals from Santiago to San Francisco

Cheapest flights from Santiago to San FranciscoExplore the most affordable flight options available from Santiago to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 30, 2025.

Explore the most affordable flight options available from Santiago to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 30, 2025.

Find flight deals from Santiago to San Francisco

Most accurate provider

Most trusted provider

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Cheapflights Fare Finder

Use the filters below to find and compare flights from Santiago to San Francisco that are best for you.

Compare providers for flights from Santiago to San Francisco

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.

Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Santiago to San Francisco in December.

Best time to book a flight from Santiago to San Francisco

Have a flexible travel schedule? Discover the best time to fly to San Francisco from Santiago with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Santiago to San Francisco

How far ahead should I book a flight from Santiago to San Francisco?

What is the cheapest month to book a flight from Santiago to San Francisco?

Reviews of airlines servicing San Francisco

Peruse reviews from past customers who have flown with Delta, Copa Airlines, and LATAM Airlines from Santiago to San Francisco to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from Santiago to San Francisco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

How long is the flight from Santiago to San Francisco?

What are the cheapest airlines flying from Santiago to San Francisco round-trip?

What are the cheapest airlines to fly from Santiago to San Francisco one-way?

Can I find deals for flights from Santiago to San Francisco that include hotel bookings?

How can I find direct flights from Santiago to San Francisco?

Can I find deals for business class flights from Santiago to San Francisco?

What is the cheapest month to book a flight from Santiago to San Francisco?

Traveling to a place near San Francisco?

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Santiago to San Francisco

See prices for flight routes from nearby airports that may be better suited for you.

Top 6 airlines flying from Santiago to San Francisco

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Cheapest flights from Santiago to San Francisco
Explore the most affordable flight options available from Santiago to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 30, 2025.