$309+ Cheap flights from Santiago (SCL) to San Francisco (SFO)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/2. Fares are subject to change and may not be available on all flights or dates of travel.
SCL — SFO
Sep 17 — Sep 241
Round-trip
1 adult, Economy
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Find cheap flights from Santiago to San Francisco with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Santiago to San Francisco
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Cheapest flights from Santiago to San FranciscoExplore the most affordable flight options available from Santiago to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 18, 2026.
Explore the most affordable flight options available from Santiago to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 18, 2026.
This LATAM Airlines deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/211:25 pm -
1 stop17h 06m
Wed 9/98:00 am -
2 stops18h 55m
Deal found 8/17![LATAM Airlines logo]()
$524
This Viajes Falabella deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Viajes Falabella is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/811:55 pm -
1 stop16h 06m
Thu 11/128:00 am -
2 stops18h 00m
Deal found 8/17![LATAM Airlines logo]()
$527
This Justfly.com deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/3111:00 pm -
2 stops19h 42m
Tue 9/158:00 am -
2 stops18h 55m
Deal found 8/17![LATAM Airlines logo]()
$533
This Copa Airlines deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/103:19 am -
1 stop19h 06m
Mon 3/297:55 pm -
1 stop24h 09m
Deal found 8/17![Copa Airlines logo]()
$538
This LATAM Airlines deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/237:30 am -
2 stops19h 53m
Wed 12/26:00 am -
1 stop19h 40m
Deal found 8/17![LATAM Airlines logo]()
$540
This Delta deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/3111:00 pm -
2 stops19h 42m
Fri 9/117:20 am -
2 stops19h 35m
Deal found 8/17![Delta logo]()
$541
This Delta deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/2411:55 pm -
1 stop16h 59m
Fri 1/16:00 am -
1 stop19h 40m
Deal found 8/17![Delta logo]()
$542
This SmartFares deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure SmartFares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/111:55 pm -
1 stop19h 59m
Thu 10/810:21 am -
1 stop15h 14m
Deal found 8/17![Multiple Airlines logo]()
$545
This LATAM Airlines deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/37:55 pm -
2 stops22h 56m
Sun 9/66:00 am -
2 stops21h 00m
Deal found 8/17![LATAM Airlines logo]()
$550
This LATAM Airlines deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/87:30 am -
2 stops18h 52m
Sat 11/146:00 am -
2 stops28h 48m
Deal found 8/17![LATAM Airlines logo]()
$551
This LATAM Airlines deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/3012:35 am -
2 stops27h 22m
Thu 10/89:54 am -
1 stop15h 41m
Deal found 8/17![LATAM Airlines logo]()
$555
Best flights from Santiago to San FranciscoDiscover carefully curated flight deals from Santiago to San Francisco that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 18, 2026.
Discover carefully curated flight deals from Santiago to San Francisco that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 18, 2026.
This Delta deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/211:25 pm -
1 stop23h 05m
Wed 9/99:00 am -
1 stop18h 25m
Deal found 8/17![Delta logo]()
$541
This LATAM Airlines deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/38:40 pm -
1 stop22h 11m
Sun 9/66:00 am -
2 stops21h 00m
Deal found 8/17![LATAM Airlines logo]()
$550
This LATAM Airlines deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/157:45 pm -
2 stops45h 35m
Tue 9/2211:30 pm -
3 stops34h 55m
Deal found 8/17![Multiple Airlines logo]()
$620
This Copa Airlines deal was found by Cheapflights users on 8/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/191:07 am -
1 stop26h 33m
Mon 11/212:33 am -
1 stop14h 42m
Deal found 8/15![Copa Airlines logo]()
$713
This American Airlines deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/289:30 pm -
2 stops22h 09m
Mon 10/58:33 am -
1 stop19h 37m
Deal found 8/14![American Airlines logo]()
$805
This LATAM Airlines deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/2511:00 pm -
2 stops26h 00m
Sat 9/122:00 pm -
2 stops21h 00m
Deal found 8/17![LATAM Airlines logo]()
$555
This LATAM Airlines deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/2511:00 pm -
2 stops26h 00m
Sat 9/122:50 pm -
1 stop37h 05m
Deal found 8/17![Multiple Airlines logo]()
$620
This Delta deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/811:55 pm -
1 stop17h 50m
Wed 10/218:00 am -
2 stops18h 55m
Deal found 8/14![Delta logo]()
$716
This Delta deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/811:55 pm -
1 stop19h 59m
Sat 11/146:00 am -
2 stops20h 15m
Deal found 8/16![Delta logo]()
$716
This Delta deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/1011:10 pm -
1 stop23h 01m
Sun 11/2211:59 pm -
2 stops24h 36m
Deal found 8/13![Delta logo]()
$719
This Delta deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1111:55 pm -
1 stop21h 03m
Sun 11/227:05 am -
1 stop17h 30m
Deal found 8/13![Delta logo]()
$809
Last-minute flights from Santiago to San FranciscoDiscover last-minute flight deals from Santiago to San Francisco. Data last updated August 18, 2026 and is based on user searches.
Discover last-minute flight deals from Santiago to San Francisco. Data last updated August 18, 2026 and is based on user searches.
This LATAM Airlines deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/2511:00 pm -
2 stops26h 00m
Mon 9/79:30 am -
1 stop16h 05m
Deal found 8/17![LATAM Airlines logo]()
$555
This Avianca deal was found by Cheapflights users on 8/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/276:40 am -
2 stops20h 15m
Tue 11/31:20 pm -
2 stops21h 00m
Deal found 8/15![Avianca logo]()
$604
This Avianca deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/276:40 am -
2 stops18h 55m
Mon 8/312:15 pm -
2 stops21h 00m
Deal found 8/13![Avianca logo]()
$606
This Justfly.com deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/3111:00 pm -
2 stops19h 42m
Tue 9/158:00 am -
2 stops18h 55m
Deal found 8/17![LATAM Airlines logo]()
$533
This Delta deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/3111:00 pm -
2 stops19h 42m
Fri 9/117:20 am -
2 stops19h 35m
Deal found 8/17![Delta logo]()
$541
This LATAM Airlines deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/14:30 pm -
2 stops30h 09m
Tue 9/156:00 am -
2 stops28h 35m
Deal found 8/17![LATAM Airlines logo]()
$551
This Cheapflightsfares deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/111:05 pm -
2 stops25h 55m
Tue 9/299:55 pm -
2 stops38h 05m
Deal found 8/17![LATAM Airlines logo]()
$605
This LATAM Airlines deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/211:25 pm -
1 stop17h 06m
Wed 9/98:00 am -
2 stops18h 55m
Deal found 8/17![LATAM Airlines logo]()
$524
This LATAM Airlines deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/37:55 pm -
2 stops22h 56m
Sun 9/66:00 am -
2 stops21h 00m
Deal found 8/17![LATAM Airlines logo]()
$550
This Expedia deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/158:55 pm -
2 stops29h 26m
Tue 9/227:20 am -
2 stops27h 40m
Deal found 8/17![LATAM Airlines logo]()
$581
This LATAM Airlines deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/165:10 am -
2 stops20h 00m
Wed 9/232:00 pm -
2 stops25h 45m
Deal found 8/17![Multiple Airlines logo]()
$615
One-way flights from Santiago to San FranciscoSearch for one-way flight options from Santiago to San Francisco. Find affordable one-way fares based on user searches. Data last updated August 18, 2026.
Search for one-way flight options from Santiago to San Francisco. Find affordable one-way fares based on user searches. Data last updated August 18, 2026.
This Avianca deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/26:40 am -
2 stops18h 55m
Deal found 8/16![Avianca logo]()
$309
This Avianca deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/127:40 am -
2 stops18h 55m
Deal found 8/16![Avianca logo]()
$310
This Avianca deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/87:40 am -
2 stops20h 15m
Deal found 8/14![Avianca logo]()
$314
This Avianca deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/97:40 am -
2 stops18h 55m
Deal found 8/16![Avianca logo]()
$321
This SmartFares deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure SmartFares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/306:40 am -
2 stops33h 10m
Deal found 8/17![Avianca logo]()
$324
This SmartFares deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure SmartFares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/316:40 am -
2 stops33h 10m
Deal found 8/14![Avianca logo]()
$329
This SmartFares deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure SmartFares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/57:40 am -
2 stops42h 55m
Deal found 8/16![Avianca logo]()
$334
This FlightHub deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/286:40 am -
2 stops42h 55m
Deal found 8/14![Avianca logo]()
$336
This Kiwi.com deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/16:40 am -
2 stops20h 15m
Deal found 8/14![Avianca logo]()
$339
This Kiwi.com deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/25:00 am -
3 stops47h 14m
Deal found 8/16![Multiple Airlines logo]()
$340
This Kiwi.com deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/56:40 am -
2 stops18h 55m
Deal found 8/16![Avianca logo]()
$341
This FlightHub deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/77:40 am -
2 stops44h 15m
Deal found 8/16![Avianca logo]()
$342
Find flight deals from Santiago to San Francisco
Discover tips and strategies to find the most affordable flight options for your journey from Santiago (SCL) to San Francisco (SFO). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated August 18, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $524 (LATAM Airlines) |
One-way from | $309 (Avianca) |
Popular in | June |
Cheapest in | October |
Average price | $668 |
Cheapflights Fare Finder
Customize your flight search to find flights from Santiago to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 18, 2026.
Use the filters below to find and compare flights from Santiago to San Francisco that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
SantiagoSan Francisco
SCL Santiago Arturo Merino Benitez - SFO San Francisco
SCLSFO
Santiago Arturo Merino Benitez
Wed 9/2
11:25 pm-7:30 pm
1 stop23h 05m
San Francisco
Wed 9/9
9:00 am-7:25 am
1 stop18h 25m
$541
SantiagoSan Francisco
SCL Santiago Arturo Merino Benitez - SFO San Francisco
SCLSFO
Santiago Arturo Merino Benitez
Thu 9/3
8:40 pm-3:51 pm
1 stop22h 11m
San Francisco
Sun 9/6
6:00 am-7:00 am
2 stops21h 00m
$550
SantiagoSan Francisco
SCL Santiago Arturo Merino Benitez - SFO San Francisco
SCLSFO
Santiago Arturo Merino Benitez
Tue 8/25
11:00 pm-10:00 pm
2 stops26h 00m
San Francisco
Sat 9/12
2:00 pm-3:00 pm
2 stops21h 00m
$555
SantiagoSan Francisco
SCL Santiago Arturo Merino Benitez - SFO San Francisco
SCLSFO
Santiago Arturo Merino Benitez
Tue 9/15
7:45 pm-1:20 pm
2 stops45h 35m
San Francisco
Tue 9/22
11:30 pm-2:25 pm
3 stops34h 55m
$620
SantiagoSan Francisco
SCL Santiago Arturo Merino Benitez - SFO San Francisco
SCLSFO
Santiago Arturo Merino Benitez
Tue 8/25
11:00 pm-10:00 pm
2 stops26h 00m
San Francisco
Sat 9/12
2:50 pm-7:55 am
1 stop37h 05m
$620
SantiagoSan Francisco
SCL Santiago Arturo Merino Benitez - SFO San Francisco
SCLSFO
Santiago Arturo Merino Benitez
Mon 10/19
1:07 am-11:40 pm
1 stop26h 33m
San Francisco
Mon 11/2
12:33 am-8:15 pm
1 stop14h 42m
$713
Quickest round-trip
SantiagoSan Francisco
SCL Santiago Arturo Merino Benitez - SFO San Francisco
SCLSFO
Santiago Arturo Merino Benitez
Thu 10/8
11:55 pm-1:45 pm
1 stop17h 50m
San Francisco
Wed 10/21
8:00 am-6:55 am
2 stops18h 55m
$716
SantiagoSan Francisco
SCL Santiago Arturo Merino Benitez - SFO San Francisco
SCLSFO
Santiago Arturo Merino Benitez
Thu 10/8
11:55 pm-3:54 pm
1 stop19h 59m
San Francisco
Sat 11/14
6:00 am-7:15 am
2 stops20h 15m
$716
SantiagoSan Francisco
SCL Santiago Arturo Merino Benitez - SFO San Francisco
SCLSFO
Santiago Arturo Merino Benitez
Tue 11/10
11:10 pm-5:11 pm
1 stop23h 01m
San Francisco
Sun 11/22
11:59 pm-5:35 am
2 stops24h 36m
$719
SantiagoSan Francisco
SCL Santiago Arturo Merino Benitez - SFO San Francisco
SCLSFO
Santiago Arturo Merino Benitez
Mon 9/28
9:30 pm-3:39 pm
2 stops22h 09m
San Francisco
Mon 10/5
8:33 am-8:10 am
1 stop19h 37m
$805
Showing 1-10 of 23 resultsSorted by cheapest first
Compare providers for flights from Santiago to San Francisco
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Santiago to San Francisco in August.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*2 stars |
- Most accurate provider: When it comes to deals on Santiago-San Francisco flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Santiago-San Francisco flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Santiago-San Francisco flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Santiago-San Francisco flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Santiago-San Francisco flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Santiago to San Francisco
Have a flexible travel schedule? Discover the best time to fly to San Francisco from Santiago with our price prediction graph.
SCL-SFO
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Santiago to San Francisco
How far ahead should I book a flight from Santiago to San Francisco?
The price you pay for your flight from Santiago to San Francisco may vary depending on when you book. For the best chance of a lower fare, look to book 6 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.
What is the cheapest month to book a flight from Santiago to San Francisco?
Currently, October is the cheapest month in which you can book a flight from Santiago to San Francisco (average of $553). Flying from Santiago to San Francisco in June is currently the most expensive (average of $787). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Santiago to San Francisco?
Airfare is below average for this route at the moment.
Santiago to San Francisco flights typically cost between $581 and $808 in September.The cheapest round-trip price found within the last 5 days was $524 on LATAM Airlines (Sep 2-Sep 9).
Reviews of airlines servicing San Francisco
Get insights into the airlines that provide service to San Francisco. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Francisco. Reviews last updated August 18, 2026.
Peruse reviews from past customers who have flown with Delta,Copa Airlines, andLATAM Airlines from Santiago to San Francisco to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
7.8
Overall
7.8
Boarding
8.1
Comfort
7.8
Food
7.2
Crew
8.5
Reviews
1 / 20
10.0
ExcellentAaron,Oct 2024
TUS - LAX
Entertainment
7.8
Overall
7.8
Boarding
8.1
Comfort
7.8
Food
7.2
Crew
8.5
Reviews
1 / 20
10.0
ExcellentAaron,Oct 2024
TUS - LAX
Entertainment
7.8
Overall
7.8
Boarding
8.1
Comfort
7.8
Food
7.2
Crew
8.5
Reviews
1 / 20
10.0
ExcellentAaron,Oct 2024
TUS - LAX
Entertainment
7.8
Overall
7.8
Boarding
8.1
Comfort
7.8
Food
7.2
Crew
8.5
Reviews
1 / 20
10.0
ExcellentAaron,Oct 2024
TUS - LAX
Entertainment
7.8
Overall
7.8
Boarding
8.1
Comfort
7.8
Food
7.2
Crew
8.5
Reviews
1 / 20
10.0
ExcellentAaron,Oct 2024
TUS - LAX
Entertainment
7.8
Overall
7.8
Boarding
8.1
Comfort
7.8
Food
7.2
Crew
8.5
Reviews
1 / 20
10.0
ExcellentAaron,Oct 2024
TUS - LAX
Related info for your journey
Find useful and relevant information for your journey from Santiago to San Francisco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near San Francisco?
Book flights to San Francisco if you plan to visit one of these locationsSouth San Francisco
Santa Clara
Santa Cruz
Walnut Creek
San Bruno
Fairfield
Emeryville
Roseville
Burlingame
Rancho Cordova
Vallejo
Cupertino
Newark
Hayward
San Ramon
Redwood City
San Carlos
Manteca
Turlock
San Lorenzo
Browse thousands of different options on Cheapflights for your next trip
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Complete your trip
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Santiago and San Francisco flights
Browse other Santiago and San Francisco flight options. Last updated on August 18, 2026.
Other flights from Santiago
Browse through other flights departing from Santiago. Flights are based on user searches made on Cheapflights and were last updated on August 18, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Other flights to San Francisco
Explore flights to San Francisco departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on August 18, 2026.
Top 6 airlines flying from Santiago to San Francisco
Discover the top 6 airlines that operate flights from Santiago to San Francisco. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 18, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$311 | Average$757 | FlexibilityNo cancel fee | On-time70% | |
| Cheapest$433 | Average$612 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$481 | Average$705 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$494 | Average$663 | FlexibilityNo cancel fee | On-time81% | |
| Cheapest$509 | Average$735 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$571 | Average$720 | FlexibilityNo cancel fee | On-time69% |