San Francisco

$267+ Cheap flights from Santiago (SCL) to San Francisco (SFO)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/23. Fares are subject to change and may not be available on all flights or dates of travel.
SCL — SFO
avr. 29 — mai 61
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Cheap flight deals from Santiago to San Francisco

Cheapest flights from Santiago to San Francisco
Explore the most affordable flight options available from Santiago to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on mars 30, 2026.

This Avianca deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 4/216:40 am
SCL
-
SFO
2 stops20h 15m
Avianca
lun. 5/42:15 pm
SFO
-
SCL
2 stops21h 00m
Avianca
Deal found 3/27$521
This Avianca deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ven. 4/246:40 am
SCL
-
SFO
2 stops18h 55m
Avianca
lun. 5/1111:55 pm
SFO
-
SCL
2 stops20h 25m
Avianca
Deal found 3/27$524
This Avianca deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ven. 5/86:40 am
SCL
-
SFO
2 stops18h 55m
Avianca
dim. 5/1711:55 pm
SFO
-
SCL
2 stops20h 25m
Avianca
Deal found 3/25$525
This Avianca deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 4/286:40 am
SCL
-
SFO
2 stops20h 15m
Avianca
mer. 5/1311:55 pm
SFO
-
SCL
2 stops20h 25m
Avianca
Deal found 3/25$527
This Avianca deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ven. 4/176:40 am
SCL
-
SFO
2 stops18h 55m
Avianca
lun. 5/42:15 pm
SFO
-
SCL
2 stops21h 00m
Avianca
Deal found 3/25$544
This Avianca deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 4/286:40 am
SCL
-
SFO
2 stops20h 15m
Avianca
ven. 5/1511:55 pm
SFO
-
SCL
2 stops20h 25m
Avianca
Deal found 3/25$547
This oojo deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dim. 5/33:20 pm
SCL
-
SFO
2 stops24h 30m
Avianca
mer. 5/2711:55 pm
SFO
-
SCL
2 stops25h 50m
Avianca
Deal found 3/30$554
This SmartFares deal was found by Cheapflights users on 3/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure SmartFares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mer. 5/203:20 pm
SCL
-
SFO
2 stops24h 30m
Avianca
sam. 5/3011:55 pm
SFO
-
SCL
2 stops25h 50m
Avianca
Deal found 3/28$555
This SmartFares deal was found by Cheapflights users on 3/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure SmartFares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dim. 4/266:40 am
SCL
-
SFO
2 stops33h 10m
Avianca
mer. 5/272:15 pm
SFO
-
SCL
2 stops21h 00m
Avianca
Deal found 3/29$557
This FlightHub deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mer. 4/14:20 pm
SCL
-
SFO
2 stops34h 15m
Avianca
jeu. 4/232:15 pm
SFO
-
SCL
2 stops21h 00m
Avianca
Deal found 3/27$558
This FlightHub deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mer. 5/611:25 pm
SCL
-
SFO
1 stop14h 28m
LATAM Airlines
lun. 5/257:15 am
SFO
-
SCL
1 stop19h 20m
LATAM Airlines
Deal found 3/25$565

Find flight deals from Santiago to San Francisco

Discover tips and strategies to find the most affordable flight options for your journey from Santiago (SCL) to San Francisco (SFO). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated mars 30, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$521
(Avianca)

One-way from

$267
(Avianca)

Popular in

June

Cheapest in

October

Average price

$602
Provider with most accurate pricing for Santiago Arturo Merino Benitez-San Francisco flight deals.
Provider most trusted by Cheapflights users for Santiago Arturo Merino Benitez-San Francisco flights.
From Santiago Arturo Merino Benitez to San Francisco
One-way flight from Santiago Arturo Merino Benitez to San Francisco
Highest demand for flights based on searches. 8% potential increase in price ($62 potential increase over avg. RT price).
Cheapest flight prices on average. 1% potential price decrease ($12 potential savings vs. average RT price).
Average for round-trip flights in March 2026

Cheapflights Fare Finder

 
Customize your flight search to find flights from Santiago to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated mars 30, 2026.
Use the filters below to find and compare flights from Santiago to San Francisco that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

SantiagoSan Francisco

SCL - SFO

SCLSFO

Santiago Arturo Merino Benitez

lun. 5/11

11:17 am-11:40 pm

1 stop15h 23m

San Francisco

dim. 6/7

1:12 am-3:00 am

1 stop22h 48m

$603

SantiagoSan Francisco

SCL - SFO

SCLSFO

Santiago Arturo Merino Benitez

lun. 5/4

11:00 pm-7:07 pm

2 stops23h 07m

San Francisco

mar. 5/12

6:00 am-7:15 am

1 stop22h 15m

$606

SantiagoSan Francisco

SCL - SFO

SCLSFO

Santiago Arturo Merino Benitez

mar. 5/5

11:00 pm-7:07 pm

2 stops23h 07m

San Francisco

ven. 9/4

8:55 am-5:35 am

1 stop17h 40m

$606

SantiagoSan Francisco

SCL - SFO

SCLSFO

Santiago Arturo Merino Benitez

mar. 5/12

2:22 am-11:40 pm

1 stop24h 18m

San Francisco

mer. 5/27

8:16 pm-7:23 pm

1 stop20h 07m

$623

SantiagoSan Francisco

SCL - SFO

SCLSFO

Santiago Arturo Merino Benitez

ven. 4/17

4:17 am-11:40 pm

1 stop22h 23m

San Francisco

sam. 5/2

1:12 am-3:00 am

1 stop22h 48m

$643

SantiagoSan Francisco

SCL - SFO

SCLSFO

Santiago Arturo Merino Benitez

jeu. 5/28

4:41 am-11:40 pm

1 stop21h 59m

San Francisco

mer. 8/19

1:12 am-10:43 pm

1 stop18h 31m

$678

SantiagoSan Francisco

SCL - SFO

SCLSFO

Santiago Arturo Merino Benitez

jeu. 5/28

10:55 pm-8:17 pm

1 stop24h 22m

San Francisco

jeu. 8/20

6:00 am-6:55 am

2 stops21h 55m

$711

SantiagoSan Francisco

SCL - SFO

SCLSFO

Santiago Arturo Merino Benitez

ven. 5/29

10:55 pm-10:49 pm

1 stop26h 54m

San Francisco

ven. 7/10

9:20 am-5:35 am

1 stop17h 15m

$721

SantiagoSan Francisco

SCL - SFO

SCLSFO

Santiago Arturo Merino Benitez

sam. 4/18

4:17 am-11:40 pm

1 stop22h 23m

San Francisco

ven. 4/24

1:23 am-10:43 pm

1 stop18h 20m

$723
Cheapest one-way

SantiagoSan Francisco

SCL - SFO

SCLSFO

Santiago Arturo Merino Benitez

jeu. 4/23

6:40 am-10:35 pm

2 stops18h 55m

$274

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/25

Showing 1-10 of 19 resultsSorted by cheapest first
1
2

Compare providers for flights from Santiago to San Francisco

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Santiago to San Francisco in March.
ProviderPrice AccuracyTrust Score*
FlightHubPrice Accuracy3 starsTrust Score*3 stars
AranGrantPrice Accuracy2 starsTrust Score*2 stars
Justfly.comPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Santiago-San Francisco flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Santiago-San Francisco flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Santiago-San Francisco flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Santiago-San Francisco flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Santiago-San Francisco flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Santiago to San Francisco

Have a flexible travel schedule? Discover the best time to fly to San Francisco from Santiago with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Santiago to San Francisco

How far ahead should I book a flight from Santiago to San Francisco?

Use this chart to determine the optimal time to book a round-trip flight from Santiago to San Francisco. Price data was last updated on March 13, 2026.

The price you pay for your flight from Santiago to San Francisco may vary depending on when you book. For the best chance of a lower fare, look to book 70 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

What is the cheapest month to book a flight from Santiago to San Francisco?

Currently, October is the cheapest month in which you can book a flight from Santiago to San Francisco (average of $465). Flying from Santiago to San Francisco in July is currently the most expensive (average of $554). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Santiago to San Francisco?

Reviews of airlines servicing San Francisco

Get insights into the airlines that provide service to San Francisco. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Francisco. Reviews last updated mars 30, 2026.
Peruse reviews from past customers who have flown with Delta,Copa Airlines, andLATAM Airlines from Santiago to San Francisco to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.

Boarding

8.1

Crew

8.5

Entertainment

7.8

Overall

7.9

Food

7.2

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Boarding

8.1

Crew

8.5

Entertainment

7.8

Overall

7.9

Food

7.2

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Boarding

8.1

Crew

8.5

Entertainment

7.8

Overall

7.9

Food

7.2

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Boarding

8.1

Crew

8.5

Entertainment

7.8

Overall

7.9

Food

7.2

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Boarding

8.1

Crew

8.5

Entertainment

7.8

Overall

7.9

Food

7.2

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Boarding

8.1

Crew

8.5

Entertainment

7.8

Overall

7.9

Food

7.2

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Related info for your journey

Find useful and relevant information for your journey from Santiago to San Francisco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • How long is the flight from Santiago to San Francisco?

    Departing from Santiago to San Francisco will take you 15h 23m. The distance from Santiago to San Francisco is about 5918 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines flying from Santiago to San Francisco round-trip?

    Currently priced at $433, Avianca will fly you from Santiago to San Francisco and back. In addition to Avianca, many other airlines offer competitively priced options for your trip. Search Cheapflights for deals from American Airlines and LATAM Airlines - these airlines can fly you to your destination from $481 and $508, respectively. Avianca is priced at 32% lower than the current average price of a flight leaving 3 months from now.

  • What are the cheapest airlines to fly from Santiago to San Francisco one-way?

    One-way options have recently been found by users for as low as $267 on Avianca. Other airlines that offer cheap prices include Copa Airlines from $277 and LATAM Airlines from $431 one-way.

  • Can I find deals for flights from Santiago to San Francisco that include hotel bookings?

    Yes. In addition to deals on Santiago to San Francisco flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Santiago to San Francisco?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santiago to San Francisco.

  • Can I find deals for business class flights from Santiago to San Francisco?

    Yes. Cheapflights offers flight deals from Santiago to San Francisco by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Santiago to San Francisco?

    Currently, October is the cheapest month in which you can book a flight from Santiago to San Francisco (average of $465). Flying from Santiago to San Francisco in July is currently the most expensive (average of $554). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near San Francisco?

Book flights to San Francisco if you plan to visit one of these locations
South San Francisco
Santa Cruz
Santa Clara
Livermore
Roseville
Rancho Cordova
San Bruno
Watsonville
San Ramon
Sunnyvale
Vacaville
San Carlos
Redwood City
Turlock
San Lorenzo
Davis
Manteca
Union City
Elk Grove
Foster City

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Santiago to San Francisco

See prices for flight routes from nearby airports that may be better suited for you.

Top 6 airlines flying from Santiago to San Francisco

Discover the top 6 airlines that operate flights from Santiago to San Francisco. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated mars 30, 2026.
AirlineCheapestAverageFlexibilityOn-time
AviancaCheapest$433Average$675FlexibilityNo cancel feeOn-time71%
American AirlinesCheapest$481Average$624FlexibilityNo cancel feeOn-time71%
LATAM AirlinesCheapest$508Average$704FlexibilityNo cancel feeOn-time81%
Copa AirlinesCheapest$511Average$627FlexibilityNo cancel feeOn-time70%
DeltaCheapest$547Average$774FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$571Average$710FlexibilityNo cancel feeOn-time69%

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