San Francisco

$131+ Cheap flights from Mississippi to San Francisco (SFO)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/18. Fares are subject to change and may not be available on all flights or dates of travel.
JAN — SFO
Apr 16 — Apr 231
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Cheap flight deals from Mississippi to San Francisco

Cheapest flights from Mississippi to San Francisco
Explore the most affordable flight options available from Mississippi to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 17, 2026.

This Frontier deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/168:30 pm
MEM
-
SFO
1 stop19h 35m
Frontier
Sat 4/257:40 pm
SFO
-
MEM
1 stop14h 39m
Frontier
Deal found 3/13$209
This Frontier deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/234:36 pm
MEM
-
SFO
1 stop9h 51m
Frontier
Sun 4/266:00 am
SFO
-
MEM
1 stop11h 02m
Frontier
Deal found 3/16$210
This Frontier deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/87:54 pm
MEM
-
SFO
1 stop6h 29m
Frontier
Mon 5/116:00 am
SFO
-
MEM
1 stop11h 09m
Frontier
Deal found 3/16$230
This Kiwi.com deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/139:17 pm
MEM
-
SFO
2 stops26h 22m
Multiple Airlines
Sun 4/196:00 am
SFO
-
MEM
1 stop11h 02m
Multiple Airlines
Deal found 3/12$261
This Booking.com deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/28:30 pm
MEM
-
SFO
1 stop13h 28m
Frontier
Wed 4/810:14 pm
SFO
-
MEM
1 stop19h 29m
Frontier
Deal found 3/13$262
This Gotogate deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/294:27 pm
MEM
-
SFO
1 stop10h 01m
Frontier
Wed 4/19:00 pm
SFO
-
MEM
1 stop15h 02m
Frontier
Deal found 3/15$269
This Priceline deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/308:01 pm
MEM
-
SFO
1 stop6h 27m
Frontier
Thu 4/26:00 am
SFO
-
MEM
1 stop6h 02m
Frontier
Deal found 3/16$270
This Frontier deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/164:36 pm
MEM
-
SFO
1 stop9h 51m
Frontier
Sun 4/196:00 am
SFO
-
MEM
1 stop11h 02m
Frontier
Deal found 3/11$280
This Booking.com deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/157:54 pm
MEM
-
SFO
1 stop17h 48m
Frontier
Mon 5/186:00 am
SFO
-
MEM
1 stop11h 09m
Frontier
Deal found 3/16$282
This Kiwi.com deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/19:53 pm
MEM
-
SFO
1 stop14h 37m
Multiple Airlines
Sun 6/710:40 pm
SFO
-
MEM
1 stop19h 59m
Multiple Airlines
Deal found 3/16$284
This American Airlines deal was found by Cheapflights users on 3/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/146:22 pm
AEX
-
SFO
1 stop7h 55m
American Airlines
Tue 10/2011:58 pm
SFO
-
AEX
1 stop7h 36m
American Airlines
Deal found 3/14$338
This Delta deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/175:55 pm
GPT
-
SFO
1 stop8h 00m
Delta
Mon 4/2011:39 pm
SFO
-
GPT
1 stop7h 45m
Delta
Deal found 3/12$349

Find flight deals from Mississippi to San Francisco

Keep the following information in mind while searching for Mississippi to San Francisco flight deals. Data was last updated March 17, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$209
(Frontier)

One-way from

$131
(Expedia)

Popular in

March

Cheapest in

October

Average price

$771
Provider with most accurate pricing for Jackson-Evers Intl-San Francisco flight deals.
Provider most trusted by Cheapflights users for Jackson-Evers Intl-San Francisco flights.
From Mississippi to San Francisco
One-way flight from Mississippi to San Francisco
Highest demand for flights based on searches. 15% potential increase in price ($82 potential increase over avg. RT price).
Cheapest flight prices on average. 7% potential price decrease ($30 potential savings vs. average RT price).
Average for round-trip flights in March 2026

Cheapflights Fare Finder

 
Customize your flight search to find flights from Mississippi to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 17, 2026.
Use the filters below to find and compare flights from Mississippi to San Francisco that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

GulfportSan Francisco

GPT - SFO

GPTSFO

Gulfport Biloxi Regional

Fri 4/17

5:55 pm-11:55 pm

1 stop8h 00m

San Francisco

Mon 4/20

11:39 pm-9:24 am

1 stop7h 45m

$349

MobileSan Francisco

MOB - SFO

MOBSFO

Mobile

Fri 4/17

4:49 pm-10:59 pm

1 stop8h 10m

San Francisco

Mon 4/20

10:28 pm-10:14 am

1 stop9h 46m

$349

AlexandriaSan Francisco

AEX - SFO

AEXSFO

Alexandria

Tue 4/14

6:26 pm-11:09 pm

1 stop6h 43m

San Francisco

Tue 4/21

11:59 pm-9:37 am

1 stop7h 38m

$358
Quickest round-trip

MemphisSan Francisco

MEM - SFO

MEMSFO

Memphis

Tue 4/7

5:55 pm-10:10 pm

1 stop6h 15m

San Francisco

Tue 4/14

6:20 am-2:20 pm

1 stop6h 00m

$359

Baton RougeSan Francisco

BTR - SFO

BTRSFO

Baton Rouge Ryan

Thu 4/30

1:37 pm-7:09 pm

1 stop7h 32m

San Francisco

Mon 5/4

9:35 pm-9:46 am

1 stop10h 11m

$369

AlexandriaSan Francisco

AEX - SFO

AEXSFO

Alexandria

Sat 3/28

6:28 pm-11:20 pm

1 stop6h 52m

San Francisco

Wed 4/1

10:25 am-11:04 pm

2 stops10h 39m

$374

JacksonSan Francisco

JAN - SFO

JANSFO

Jackson-Evers Intl

Thu 4/2

12:55 pm-8:25 pm

1 stop9h 30m

San Francisco

Mon 4/6

10:35 pm-10:08 am

1 stop9h 33m

$379

Baton RougeSan Francisco

BTR - SFO

BTRSFO

Baton Rouge Ryan

Fri 3/27

6:45 pm-11:59 pm

1 stop7h 14m

San Francisco

Tue 3/31

2:22 pm-10:45 pm

1 stop6h 23m

$399

JacksonSan Francisco

JAN - SFO

JANSFO

Jackson-Evers Intl

Thu 4/30

12:15 pm-8:00 pm

2 stops9h 45m

San Francisco

Thu 5/7

11:10 am-9:00 pm

2 stops7h 50m

$409

MobileSan Francisco

MOB - SFO

MOBSFO

Mobile

Thu 8/27

6:00 am-1:21 pm

1 stop9h 21m

San Francisco

Tue 9/1

1:45 pm-10:55 pm

1 stop7h 10m

$409

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/15

Showing 1-10 of 60 resultsSorted by cheapest first
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Best time to book a flight from Mississippi to San Francisco

Have a flexible travel schedule? Discover the best time to fly to San Francisco from Mississippi with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Mississippi to San Francisco

What is the cheapest month to book a flight from Mississippi to San Francisco?

Currently, August is the cheapest month in which you can book a flight from Mississippi to San Francisco (average of $192). Flying from Mississippi to San Francisco in April is currently the most expensive (average of $387). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from Mississippi to San Francisco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • What airport do you fly into for flights to San Francisco from Mississippi?

    San Francisco (SFO) is the airport you will fly into if you book a flight from Mississippi to San Francisco. It is only a 11.8 mi journey from San Francisco (SFO) to San Francisco’s city center.

  • How long is the flight from Mississippi to San Francisco?

    Departing from Mississippi to San Francisco will take you 6h 15m. Airlines will cover a distance of 1802 mi. This flight may include one or multiple stops.

  • What are the most popular routes from Mississippi to San Francisco?

  • Can I find deals for flights from Mississippi to San Francisco that include hotel bookings?

    Yes. In addition to deals on Mississippi to San Francisco flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Mississippi to San Francisco?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Mississippi to San Francisco.

  • Can I find deals for business class flights from Mississippi to San Francisco?

    Yes. Cheapflights offers flight deals from Mississippi to San Francisco by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Mississippi to San Francisco?

    Currently, August is the cheapest month in which you can book a flight from Mississippi to San Francisco (average of $192). Flying from Mississippi to San Francisco in April is currently the most expensive (average of $387). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near San Francisco?

Book flights to San Francisco if you plan to visit one of these locations
South San Francisco
Santa Clara
Santa Cruz
Livermore
Roseville
Watsonville
Rancho Cordova
San Bruno
San Ramon
Sunnyvale
Vacaville
San Carlos
Redwood City
Turlock
San Lorenzo
Davis
Manteca
Union City
Elk Grove
Rohnert Park

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Mississippi to San Francisco

See prices for flight routes from nearby airports that may be better suited for you.

Top 2 airlines flying from Mississippi to San Francisco

Discover the top 2 airlines that operate flights from Mississippi to San Francisco. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 17, 2026.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$192Average$477FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$283Average$382FlexibilityNo cancel feeOn-time71%

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