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$76+ Cheap flights from Mississippi to San Francisco (SFO)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/12. Fares are subject to change and may not be available on all flights or dates of travel.
JAN — SFO
Dec 24 — Dec 311
Wed 12/24
Wed 12/31
1 adult, Economy
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Cheap flight deals from Mississippi to San Francisco

Keep the following information in mind while searching for Mississippi to San Francisco flight deals. Data was last updated November 24, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$188
(Kiwi.com)

One-way from

$76
(Trip.com)

Popular in

March

Cheapest in

October

Average price

$506
Provider with most accurate pricing for Jackson-Evers Intl-San Francisco flight deals.
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Provider most trusted by Cheapflights users for Jackson-Evers Intl-San Francisco flights.
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From Mississippi to San Francisco
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One-way flight from Mississippi to San Francisco
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Highest demand for flights based on searches. 14% potential increase in price ($79 potential increase over avg. RT price).
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Cheapest flight prices on average. 4% potential price decrease ($20 potential savings vs. average RT price).
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Average for round-trip flights in November 2025
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Find flight deals from Mississippi to San Francisco

Cheapest flights from Mississippi to San Francisco
Explore the most affordable flight options available from Mississippi to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 24, 2025.

This Trip.com deal was found by Cheapflights users on 11/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/48:07 pmMEM - SFO
1 stop6h 17mFrontier
Thu 12/116:30 amSFO - MEM
1 stop10h 42mFrontier
Deal found 11/21$196
This Kiwi.com deal was found by Cheapflights users on 11/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/59:17 pmMEM - SFO
1 stop12h 31mMultiple Airlines
Sun 12/75:46 pmSFO - MEM
1 stop24h 41mMultiple Airlines
Deal found 11/21$201
This Expedia deal was found by Cheapflights users on 11/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/78:07 pmMEM - SFO
1 stop13h 46mFrontier
Thu 12/116:30 amSFO - MEM
1 stop10h 42mFrontier
Deal found 11/23$207
This Kiwi.com deal was found by Cheapflights users on 11/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/245:54 pmMEM - SFO
1 stop29h 42mMultiple Airlines
Tue 12/301:29 pmSFO - MEM
1 stop25h 20mMultiple Airlines
Deal found 11/20$221
This Priceline deal was found by Cheapflights users on 11/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/118:07 pmMEM - SFO
1 stop6h 17mFrontier
Sun 12/146:30 amSFO - MEM
1 stop10h 42mFrontier
Deal found 11/23$228
This Frontier deal was found by Cheapflights users on 11/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/188:07 pmMEM - SFO
1 stop6h 17mFrontier
Thu 12/256:24 amSFO - MEM
1 stop10h 48mFrontier
Deal found 11/23$232
This Kiwi.com deal was found by Cheapflights users on 11/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/97:42 pmMEM - SFO
2 stops29h 25mMultiple Airlines
Sat 12/136:00 amSFO - MEM
1 stop6h 54mMultiple Airlines
Deal found 11/23$275
This United Airlines deal was found by Cheapflights users on 11/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/2110:39 amPIB - SFO
1 stop9h 19mUnited Airlines
Thu 1/15:15 amSFO - PIB
1 stop7h 09mUnited Airlines
Deal found 11/23$284
This Kiwi.com deal was found by Cheapflights users on 11/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/225:54 pmMEM - SFO
1 stop20h 40mMultiple Airlines
Mon 12/299:30 pmSFO - MEM
2 stops41h 19mMultiple Airlines
Deal found 11/22$284
This Kiwi.com deal was found by Cheapflights users on 11/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/158:52 pmMEM - SFO
1 stop21h 59mMultiple Airlines
Fri 12/196:00 amSFO - MEM
1 stop12h 27mMultiple Airlines
Deal found 11/21$289
This Delta deal was found by Cheapflights users on 11/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/126:01 pmGPT - SFO
1 stop8h 19mDelta
Mon 12/156:00 amSFO - GPT
1 stop9h 16mDelta
Deal found 11/22$324
This United Airlines deal was found by Cheapflights users on 11/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/1211:30 amMOB - SFO
1 stop7h 16mUnited Airlines
Tue 12/168:25 amSFO - MOB
1 stop9h 57mUnited Airlines
Deal found 11/23$324

Cheapflights Fare Finder

 
Customize your flight search to find flights from Mississippi to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 24, 2025.
Use the filters below to find and compare flights from Mississippi to San Francisco that are best for you.

Fly from

Mississippi

Fly to

San Francisco

Route

Depart

Return

Price

MemphisSan Francisco

MEM - SFO

MEMSFO

Memphis

Wed 12/24

5:54 pm-9:36 pm

1 stop29h 42m

San Francisco

Tue 12/30

1:29 pm-4:49 pm

1 stop25h 20m

$221

MemphisSan Francisco

MEM - SFO

MEMSFO

Memphis

Thu 12/18

8:07 pm-12:24 am

1 stop6h 17m

San Francisco

Thu 12/25

6:24 am-7:12 pm

1 stop10h 48m

$232

MemphisSan Francisco

MEM - SFO

MEMSFO

Memphis

Fri 1/16

1:21 pm-7:12 pm

1 stop7h 51m

San Francisco

Mon 1/19

11:55 am-10:19 am

2 stops44h 24m

$262

AlexandriaSan Francisco

AEX - SFO

AEXSFO

Alexandria

Tue 1/27

11:44 am-8:25 pm

1 stop10h 41m

San Francisco

Sat 1/31

11:50 am-9:00 pm

1 stop7h 10m

$278

MemphisSan Francisco

MEM - SFO

MEMSFO

Memphis

Sun 12/7

8:07 pm-12:24 am

1 stop6h 17m

San Francisco

Thu 12/11

6:30 am-7:12 pm

1 stop10h 42m

$282

LaurelSan Francisco

PIB - SFO

PIBSFO

Laurel Hattiesburg-PineBelt

Sun 12/21

10:39 am-5:58 pm

1 stop9h 19m

San Francisco

Thu 1/1

5:15 am-2:24 pm

1 stop7h 09m

$284

MemphisSan Francisco

MEM - SFO

MEMSFO

Memphis

Mon 12/22

5:54 pm-12:34 pm

1 stop20h 40m

San Francisco

Mon 12/29

9:30 pm-4:49 pm

2 stops41h 19m

$284

MobileSan Francisco

MOB - SFO

MOBSFO

Mobile

Fri 2/6

10:44 am-4:50 pm

1 stop8h 06m

San Francisco

Tue 2/10

7:18 am-4:09 pm

1 stop6h 51m

$289

MobileSan Francisco

MOB - SFO

MOBSFO

Mobile

Tue 1/27

12:34 pm-8:25 pm

1 stop9h 51m

San Francisco

Sat 1/31

10:00 pm-8:31 am

1 stop8h 31m

$289

MobileSan Francisco

MOB - SFO

MOBSFO

Mobile

Thu 1/22

12:34 pm-7:49 pm

1 stop9h 15m

San Francisco

Tue 1/27

11:40 am-10:43 pm

1 stop9h 03m

$289

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/20

Showing 1-10 of 54 results
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Best time to book a flight from Mississippi to San Francisco

Have a flexible travel schedule? Discover the best time to fly to San Francisco from Mississippi with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Mississippi to San Francisco

What is the cheapest month to book a flight from Mississippi to San Francisco?

Currently, August is the cheapest month in which you can book a flight from Mississippi to San Francisco (average of $192). Flying from Mississippi to San Francisco in April is currently the most expensive (average of $387). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MS to SFO?

Find hourly flight availability from Mississippi to San Francisco. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated November 24, 2025.

One of the essential ways to save on airfare from Mississippi to San Francisco is to remain as flexible as possible. Flights that are at noon tend to be the most expensive. A flight in the afternoon could potentially save you up to 33% on airfare.

What is the cheapest day to fly from Mississippi to San Francisco?

Use this chart to determine the cheapest time to fly round-trip from Mississippi to San Francisco. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Mississippi to San Francisco flight should consider departing on Wednesday afternoons when fares are most often at their lowest. Sunday at noon flights should be avoided if possible as fares are typically the most expensive at this time.

Related info for your journey

Find useful and relevant information for your journey from Mississippi to San Francisco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to San Francisco from Mississippi?

    San Francisco (SFO) is the airport you will fly into if you book a flight from Mississippi to San Francisco. It is only a 11.8 mi journey from San Francisco (SFO) to San Francisco’s city center.

  • How long is the flight from Mississippi to San Francisco?

    Departing from Mississippi to San Francisco will take you 6h 17m. Airlines will cover a distance of 1802 mi. This flight may include one or multiple stops.

  • What are the most popular routes from Mississippi to San Francisco?

    The most popular flight routes from Mississippi to San Francisco are Memphis - San Francisco, Baton Rouge Ryan - San Francisco and Jackson-Evers Intl - San Francisco.

  • Can I find deals for flights from Mississippi to San Francisco that include hotel bookings?

    Yes. In addition to deals on Mississippi to San Francisco flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Mississippi to San Francisco?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Mississippi to San Francisco.

  • Can I find deals for business class flights from Mississippi to San Francisco?

    Yes. Cheapflights offers flight deals from Mississippi to San Francisco by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Mississippi to San Francisco?

    Currently, August is the cheapest month in which you can book a flight from Mississippi to San Francisco (average of $192). Flying from Mississippi to San Francisco in April is currently the most expensive (average of $387). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near San Francisco?

Book flights to San Francisco if you plan to visit one of these locations
Roseville
South San Francisco
Santa Cruz
Livermore
Turlock
Manteca
Watsonville
Sunnyvale
Santa Clara
Vallejo
Hollister
San Bruno
Foster City
Redwood City
Union City
Burlingame
Lodi
San Mateo
Vacaville
Lathrop

Browse thousands of different options on Cheapflights for your next trip

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Top 2 airlines flying from Mississippi to San Francisco

Discover the top 2 airlines that operate flights from Mississippi to San Francisco. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 24, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$192Average$518FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$288Average$423FlexibilityNo cancel feeOn-time71%

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