$135+ Cheap flights from Indianapolis to San Francisco (IND - SFO)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/7. Fares are subject to change and may not be available on all flights or dates of travel.
IND — SFO
Sep 5 — Sep 121
Round-trip
1 adult, Economy
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Find cheap flights from Indianapolis to San Francisco with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheapflights Tip: The best prices from Indianapolis to San Francisco are usually found in September or April, booked 66 days in advance, depart on a Friday or Thursday and return on a Saturday
Cheap flight deals from Indianapolis to San Francisco
Cheapest
Best
Last-minute
One-way
Cheapest flights from Indianapolis to San FranciscoExplore the most affordable flight options available from Indianapolis to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 6, 2026.
Explore the most affordable flight options available from Indianapolis to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 6, 2026.
This Kiwi.com deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/308:49 pm -
1 stop6h 29m
Tue 9/111:38 am -
2 stops14h 35m
Deal found 8/1![Multiple Airlines logo]()
$326
This Expedia deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/267:02 am -
2 stops13h 20m
Thu 9/37:30 pm -
1 stop21h 34m
Deal found 8/1![Multiple Airlines logo]()
$327
This Kiwi.com deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/118:16 pm -
2 stops17h 31m
Wed 10/1410:48 pm -
1 stop9h 56m
Deal found 8/1![Frontier logo]()
$328
This Frontier deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/238:49 pm -
1 stop6h 29m
Tue 8/256:00 am -
1 stop11h 04m
Deal found 8/4![Frontier logo]()
$329
This Kiwi.com deal was found by Cheapflights users on 8/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/912:39 pm -
1 stop8h 41m
Tue 10/136:22 am -
2 stops9h 59m
Deal found 8/2![Frontier logo]()
$330
This Alaska Airlines deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/295:26 pm -
1 stop8h 24m
Wed 9/910:32 am -
2 stops15h 41m
Deal found 8/3![Alaska Airlines logo]()
$331
This Kiwi.com deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/46:11 pm -
1 stop27h 52m
Sun 9/136:04 am -
1 stop6h 13m
Deal found 8/3![Frontier logo]()
$332
This Kiwi.com deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/79:59 pm -
1 stop14h 17m
Sun 9/136:04 am -
1 stop6h 13m
Deal found 8/1![Frontier logo]()
$333
This Frontier deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/308:49 pm -
1 stop6h 29m
Fri 9/46:00 am -
1 stop11h 04m
Deal found 8/1![Frontier logo]()
$334
This CheapOair deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/169:33 pm -
1 stop29h 45m
Sat 8/227:30 pm -
1 stop21h 34m
Deal found 8/5![Frontier logo]()
$335
This Alaska Airlines deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/175:28 pm -
1 stop9h 12m
Mon 10/511:40 am -
2 stops14h 51m
Deal found 8/1![Alaska Airlines logo]()
$336
This Kiwi.com deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/198:49 pm -
1 stop6h 29m
Thu 8/273:38 pm -
2 stops16h 39m
Deal found 8/3![Frontier logo]()
$337
Best flights from Indianapolis to San FranciscoDiscover carefully curated flight deals from Indianapolis to San Francisco that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 6, 2026.
Discover carefully curated flight deals from Indianapolis to San Francisco that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 6, 2026.
This United Airlines deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/174:57 pm -
Nonstop4h 45m
Sun 9/203:35 pm -
Nonstop4h 24m
Deal found 8/5![United Airlines logo]()
$339
This Alaska Airlines deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/17:02 am -
2 stops11h 57m
Wed 9/911:38 am -
2 stops14h 35m
Deal found 8/3![Alaska Airlines logo]()
$363
This Southwest deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/91:55 pm -
2 stops8h 15m
Mon 9/142:00 pm -
2 stops8h 20m
Deal found 8/5![Southwest logo]()
$369
This United Airlines deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/187:00 am -
1 stop8h 19m
Wed 11/2510:53 pm -
Nonstop4h 19m
Deal found 8/3![United Airlines logo]()
$345
This Southwest deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/56:05 am -
2 stops8h 15m
Fri 10/99:55 am -
2 stops11h 25m
Deal found 8/3![Southwest logo]()
$371
This Alaska Airlines deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/127:02 am -
2 stops13h 20m
Fri 9/188:53 pm -
1 stop16h 34m
Deal found 8/1![Alaska Airlines logo]()
$385
This Southwest deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/86:05 am -
2 stops8h 15m
Tue 10/139:30 am -
2 stops8h 50m
Deal found 8/4![Southwest logo]()
$381
This Alaska Airlines deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/287:02 am -
2 stops13h 42m
Sat 10/3110:40 am -
2 stops15h 48m
Deal found 8/5![Alaska Airlines logo]()
$433
This United Airlines deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/157:00 am -
1 stop7h 44m
Sun 11/110:53 pm -
Nonstop4h 19m
Deal found 8/4![United Airlines logo]()
$436
This Southwest deal was found by Cheapflights users on 8/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/86:05 am -
2 stops8h 15m
Mon 10/129:55 am -
2 stops11h 25m
Deal found 8/2![Southwest logo]()
$403
This Alaska Airlines deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/187:04 am -
1 stop10h 00m
Tue 8/2511:56 am -
2 stops14h 17m
Deal found 8/3![Alaska Airlines logo]()
$433
This United Airlines deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/47:25 am -
Nonstop4h 50m
Sun 9/68:20 am -
Nonstop4h 24m
Deal found 8/1![United Airlines logo]()
$439
Last-minute flights from Indianapolis to San FranciscoDiscover last-minute flight deals from Indianapolis to San Francisco. Data last updated August 6, 2026 and is based on user searches.
Discover last-minute flight deals from Indianapolis to San Francisco. Data last updated August 6, 2026 and is based on user searches.
This CheapOair deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/169:33 pm -
1 stop29h 45m
Sat 8/227:30 pm -
1 stop21h 34m
Deal found 8/5![Frontier logo]()
$335
This Kiwi.com deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/188:49 pm -
1 stop6h 29m
Thu 8/2711:00 am -
2 stops21h 17m
Deal found 8/4![Frontier logo]()
$338
This Kiwi.com deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/198:49 pm -
1 stop6h 29m
Thu 8/273:38 pm -
2 stops16h 39m
Deal found 8/3![Frontier logo]()
$337
This Kiwi.com deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/218:49 pm -
1 stop6h 29m
Sun 8/231:07 pm -
2 stops27h 57m
Deal found 8/3![Frontier logo]()
$330
This Frontier deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/238:49 pm -
1 stop6h 29m
Tue 8/256:00 am -
1 stop11h 04m
Deal found 8/4![Frontier logo]()
$329
This Expedia deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/267:02 am -
2 stops13h 20m
Thu 9/37:30 pm -
1 stop21h 34m
Deal found 8/1![Multiple Airlines logo]()
$327
This Alaska Airlines deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/295:26 pm -
1 stop8h 24m
Wed 9/910:32 am -
2 stops15h 41m
Deal found 8/3![Alaska Airlines logo]()
$331
This Kiwi.com deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/308:49 pm -
1 stop6h 29m
Tue 9/111:38 am -
2 stops14h 35m
Deal found 8/1![Multiple Airlines logo]()
$326
This Frontier deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/308:49 pm -
1 stop6h 29m
Fri 9/46:00 am -
1 stop11h 04m
Deal found 8/1![Frontier logo]()
$334
This Kiwi.com deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/46:11 pm -
1 stop27h 52m
Sun 9/136:04 am -
1 stop6h 13m
Deal found 8/3![Frontier logo]()
$332
This Kiwi.com deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/79:59 pm -
1 stop14h 17m
Sun 9/136:04 am -
1 stop6h 13m
Deal found 8/1![Frontier logo]()
$333
This Alaska Airlines deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/175:28 pm -
1 stop9h 12m
Mon 10/511:40 am -
2 stops14h 51m
Deal found 8/1![Alaska Airlines logo]()
$336
One-way flights from Indianapolis to San FranciscoSearch for one-way flight options from Indianapolis to San Francisco. Find affordable one-way fares based on user searches. Data last updated August 6, 2026.
Search for one-way flight options from Indianapolis to San Francisco. Find affordable one-way fares based on user searches. Data last updated August 6, 2026.
This Kiwi.com deal was found by Cheapflights users on 8/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/74:12 pm -
1 stop11h 02m
Deal found 8/2![Frontier logo]()
$135
This Kiwi.com deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/268:49 pm -
2 stops18h 03m
Deal found 8/3![Frontier logo]()
$138
This Alaska Airlines deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/157:02 am -
2 stops13h 20m
Deal found 8/1![Alaska Airlines logo]()
$142
This Super.com deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/178:53 pm -
1 stop6h 25m
Deal found 8/3![Frontier logo]()
$143
This Frontier deal was found by Cheapflights users on 8/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/228:49 pm -
1 stop6h 29m
Deal found 8/2![Frontier logo]()
$145
This Alaska Airlines deal was found by Cheapflights users on 8/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/245:28 pm -
2 stops24h 17m
Deal found 8/2![Alaska Airlines logo]()
$148
This Alaska Airlines deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/77:02 am -
2 stops15h 29m
Deal found 8/4![Alaska Airlines logo]()
$152
This Kiwi.com deal was found by Cheapflights users on 8/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/232:02 pm -
1 stop21h 41m
Deal found 8/2![Multiple Airlines logo]()
$153
This Kiwi.com deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/57:48 pm -
2 stops29h 40m
Deal found 8/1![Frontier logo]()
$154
Find flight deals from Indianapolis to San Francisco
Discover tips and strategies to find the most affordable flight options for your journey from Indianapolis (IND) to San Francisco (SFO). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated August 6, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $326 (Kiwi.com) |
One-way from | $135 (Kiwi.com) |
Popular in | March |
Cheapest in | September |
Average price | $429 |
Good round-trip deal | $421 or less |
Good one-way deal | $303 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Indianapolis to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 6, 2026.
Use the filters below to find and compare flights from Indianapolis to San Francisco that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
IndianapolisSan Francisco
IND Indianapolis - SFO San Francisco
INDSFO
Indianapolis
Thu 9/17
4:57 pm-6:42 pm
Nonstop4h 45m
San Francisco
Sun 9/20
3:35 pm-10:59 pm
Nonstop4h 24m
$339
IndianapolisSan Francisco
IND Indianapolis - SFO San Francisco
INDSFO
Indianapolis
Wed 11/18
7:00 am-12:19 pm
1 stop8h 19m
San Francisco
Wed 11/25
10:53 pm-6:12 am
Nonstop4h 19m
$345
IndianapolisSan Francisco
IND Indianapolis - SFO San Francisco
INDSFO
Indianapolis
Tue 9/1
7:02 am-3:59 pm
2 stops11h 57m
San Francisco
Wed 9/9
11:38 am-5:13 am
2 stops14h 35m
$363
IndianapolisSan Francisco
IND Indianapolis - SFO San Francisco
INDSFO
Indianapolis
Wed 9/9
1:55 pm-7:10 pm
2 stops8h 15m
San Francisco
Mon 9/14
2:00 pm-1:20 am
2 stops8h 20m
$369
IndianapolisSan Francisco
IND Indianapolis - SFO San Francisco
INDSFO
Indianapolis
Mon 10/5
6:05 am-11:20 am
2 stops8h 15m
San Francisco
Fri 10/9
9:55 am-12:20 am
2 stops11h 25m
$371
IndianapolisSan Francisco
IND Indianapolis - SFO San Francisco
INDSFO
Indianapolis
Thu 10/8
6:05 am-11:20 am
2 stops8h 15m
San Francisco
Tue 10/13
9:30 am-9:20 pm
2 stops8h 50m
$381
IndianapolisSan Francisco
IND Indianapolis - SFO San Francisco
INDSFO
Indianapolis
Sat 9/12
7:02 am-5:22 pm
2 stops13h 20m
San Francisco
Fri 9/18
8:53 pm-4:27 pm
1 stop16h 34m
$385
IndianapolisSan Francisco
IND Indianapolis - SFO San Francisco
INDSFO
Indianapolis
Thu 10/8
6:05 am-11:20 am
2 stops8h 15m
San Francisco
Mon 10/12
9:55 am-12:20 am
2 stops11h 25m
$403
IndianapolisSan Francisco
IND Indianapolis - SFO San Francisco
INDSFO
Indianapolis
Wed 10/28
7:02 am-5:44 pm
2 stops13h 42m
San Francisco
Sat 10/31
10:40 am-5:28 am
2 stops15h 48m
$433
IndianapolisSan Francisco
IND Indianapolis - SFO San Francisco
INDSFO
Indianapolis
Tue 8/18
7:04 am-2:04 pm
1 stop10h 00m
San Francisco
Tue 8/25
11:56 am-5:13 am
2 stops14h 17m
$433
Showing 1-10 of 22 resultsSorted by cheapest first
Compare providers for flights from Indianapolis to San Francisco
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Indianapolis to San Francisco in August.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy- | Trust Score*1 star | |
| Price Accuracy2 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Indianapolis-San Francisco flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Indianapolis-San Francisco flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Indianapolis-San Francisco flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Indianapolis-San Francisco flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Indianapolis-San Francisco flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Indianapolis to San Francisco
Have a flexible travel schedule? Discover the best time to fly to San Francisco from Indianapolis with our price prediction graph.
IND-SFO
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Indianapolis to San Francisco
Prices
More
How far ahead should I book a flight from Indianapolis to San Francisco?
The best time to book flights from Indianapolis to San Francisco is 65 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.
What is the cheapest month to book a flight from Indianapolis to San Francisco?
Currently, September is the cheapest month in which you can book a flight from Indianapolis to San Francisco (average of $361). Flying from Indianapolis to San Francisco in March is currently the most expensive (average of $457). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from IND to SFO?
Find hourly flight availability from Indianapolis to San Francisco. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated August 6, 2026.
When flying from Indianapolis to San Francisco, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.
What’s the top layover airport for flights from Indianapolis to San Francisco?
Share of 1-stop round-trip flights from Indianapolis to San Francisco chosen by Cheapflights users in the past 12 months, using the same layover each way.
Las Vegas (LAS) – chosen by Cheapflights users on 50% of 1-stop itineraries from Indianapolis to San Francisco on Cheapflights.
What’s the cheapest layover airport for flights from Indianapolis to San Francisco?
Average round-trip fare for 1-stop flights from Indianapolis to San Francisco, chosen by Cheapflights users in the past 12 months, with the same layover each way.
Las Vegas (LAS) is the most affordable 1-stop option, with an average round-trip price of $252.
What’s the fastest layover option from Indianapolis to San Francisco?
Shortest average travel time for 1-stop one-way flights from Indianapolis to San Francisco, based on itineraries clicked by Cheapflights users over the past 12 months, grouped by layover airport.
Flights via Denver (DEN) have the shortest average one-way travel time for 1-stop routes: 6h 27m.
Which airport typically offers the quickest layover for flights from Indianapolis to San Francisco?
Average layover duration for 1-stop one-way flights from Indianapolis to San Francisco, chosen by Cheapflights users in the last 12 months, grouped by stopover airport.
Flights via Los Angeles (LAX) offer the fastest connection on this route, with an average layover time of 1h 07m.
The best insider tips for Indianapolis to San Francisco flights
AI-powered summary based on content written by travel experts. AI can make mistakes.
Cheapflights partnered with top experts to bring you the best recommendations for your Indianapolis to San Francisco trip
Our travel experts
Reviews of airlines servicing San Francisco
Get insights into the airlines that provide service to San Francisco. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Francisco. Reviews last updated August 6, 2026.
Get a feel of what it's like to fly with Southwest,Delta, andUnited Airlines from Indianapolis to San Francisco by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Comfort
8.0
Crew
8.6
Boarding
8.1
Food
7.0
Overall
8.0
Entertainment
7.5
Reviews
1 / 20
10.0
ExcellentWalter,May 2026
LAS - BUR
Comfort
8.0
Crew
8.6
Boarding
8.1
Food
7.0
Overall
8.0
Entertainment
7.5
Reviews
1 / 20
10.0
ExcellentWalter,May 2026
LAS - BUR
Comfort
8.0
Crew
8.6
Boarding
8.1
Food
7.0
Overall
8.0
Entertainment
7.5
Reviews
1 / 20
10.0
ExcellentWalter,May 2026
LAS - BUR
Comfort
8.0
Crew
8.6
Boarding
8.1
Food
7.0
Overall
8.0
Entertainment
7.5
Reviews
1 / 20
10.0
ExcellentWalter,May 2026
LAS - BUR
Comfort
8.0
Crew
8.6
Boarding
8.1
Food
7.0
Overall
8.0
Entertainment
7.5
Reviews
1 / 20
10.0
ExcellentWalter,May 2026
LAS - BUR
Comfort
8.0
Crew
8.6
Boarding
8.1
Food
7.0
Overall
8.0
Entertainment
7.5
Reviews
1 / 20
10.0
ExcellentWalter,May 2026
LAS - BUR
Related info for your journey
Find useful and relevant information for your journey from Indianapolis to San Francisco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near San Francisco?
Book flights to San Francisco if you plan to visit one of these locationsSouth San Francisco
Santa Clara
Santa Cruz
San Bruno
Fairfield
Emeryville
Roseville
Burlingame
Rancho Cordova
Vallejo
Cupertino
Newark
Hayward
San Ramon
Redwood City
San Carlos
Milpitas
Turlock
San Lorenzo
Davis
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Top 6 airlines flying from Indianapolis to San Francisco
Discover the top 6 airlines that operate flights from Indianapolis to San Francisco. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 6, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$119 | Average$280 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$220 | Average$387 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$238 | Average$370 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$269 | Average$420 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$278 | Average$441 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$284 | Average$428 | FlexibilityNo cancel fee | On-time63% |