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$76+ Cheap flights from Indiana to San Francisco (SFO)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/14. Fares are subject to change and may not be available on all flights or dates of travel.
IND — SFO
Feb 28 — Mar 71
Sat 2/28
Sat 3/7
1 adult, Economy
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Cheap flight deals from Indiana to San Francisco

Cheapest flights from Indiana to San Francisco
Explore the most affordable flight options available from Indiana to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 29, 2026.

This Kiwi.com deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/263:00 pm
MDW
-
SFO
2 stops19h 17m
Frontier
Sun 3/111:09 pm
SFO
-
MDW
1 stop18h 38m
Frontier
Deal found 1/28$242
This Kiwi.com deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/148:15 am
ORD
-
SFO
2 stops28h 00m
Frontier
Wed 2/1810:58 pm
SFO
-
ORD
1 stop9h 53m
Frontier
Deal found 1/27$242
This Alaska Airlines deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/98:50 am
ORD
-
SFO
1 stop12h 48m
Alaska Airlines
Tue 5/127:15 am
SFO
-
ORD
1 stop9h 48m
Alaska Airlines
Deal found 1/28$243
This Kiwi.com deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/1811:51 am
ORD
-
SFO
1 stop11h 48m
Frontier
Sat 2/218:58 am
SFO
-
ORD
2 stops12h 19m
Frontier
Deal found 1/27$244
This Kiwi.com deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/1112:36 pm
ORD
-
SFO
1 stop11h 03m
Frontier
Tue 2/1710:55 pm
SFO
-
ORD
1 stop15h 57m
Frontier
Deal found 1/28$245
This Kiwi.com deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/106:07 pm
ORD
-
SFO
2 stops32h 21m
Frontier
Sat 2/1411:00 pm
SFO
-
ORD
1 stop9h 46m
Frontier
Deal found 1/26$246
This Southwest deal was found by Cheapflights users on 1/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/32:10 pm
MDW
-
SFO
1 stop8h 05m
Southwest
Tue 3/1011:25 pm
SFO
-
MDW
Nonstop4h 05m
Southwest
Deal found 1/29$247
This Kiwi.com deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/186:51 pm
ORD
-
SFO
2 stops28h 48m
Multiple Airlines
Sun 2/2210:46 pm
SFO
-
ORD
1 stop10h 05m
Multiple Airlines
Deal found 1/28$247
This Kiwi.com deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/1112:36 pm
ORD
-
SFO
1 stop11h 03m
Frontier
Thu 2/128:48 am
SFO
-
ORD
1 stop12h 26m
Frontier
Deal found 1/27$248
This Kiwi.com deal was found by Cheapflights users on 1/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/1912:22 pm
MDW
-
SFO
1 stop11h 17m
Frontier
Thu 2/268:43 am
SFO
-
MDW
2 stops10h 29m
Frontier
Deal found 1/29$249
This Cheapflightsfares deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/147:55 am
ORD
-
SFO
1 stop12h 03m
Frontier
Mon 2/1610:58 pm
SFO
-
ORD
1 stop9h 32m
Frontier
Deal found 1/27$249
This Southwest deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/1110:05 am
MDW
-
SFO
Nonstop4h 40m
Southwest
Sun 3/155:05 am
SFO
-
MDW
Nonstop4h 00m
Southwest
Deal found 1/26$250

Find flight deals from Indiana to San Francisco

Keep the following information in mind while searching for Indiana to San Francisco flight deals. Data was last updated January 29, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$242
(Kiwi.com)

One-way from

$76
(Kiwi.com)

Popular in

December

Cheapest in

February

Average price

$399

Good round-trip deal

$338 or less

Good one-way deal

$214 or less
Provider with most accurate pricing for Indianapolis-San Francisco flight deals.
Search Deals
Provider most trusted by Cheapflights users for Indianapolis-San Francisco flights.
Search Deals
From Indiana to San Francisco
Search Deals
One-way flight from Indiana to San Francisco
Search Deals
Highest demand for flights based on searches. 6% potential increase in price ($26 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($5 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in January 2026
Search Deals
Price to beat on a round-trip flight from Indiana to San Francisco.
Search Deals
Price to beat on a one-way flight from Indiana to San Francisco.
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Indiana to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 29, 2026.
Use the filters below to find and compare flights from Indiana to San Francisco that are best for you.

Fly from

Indiana

Fly to

San Francisco

Route

Depart

Return

Price

ChicagoSan Francisco

ORD - SFO

ORDSFO

Chicago O'Hare Intl

Fri 3/6

9:15 pm-12:16 am

Nonstop5h 01m

San Francisco

Sat 3/14

6:44 pm-12:59 am

Nonstop4h 15m

$250

ChicagoSan Francisco

MDW - SFO

MDWSFO

Chicago Midway

Tue 3/3

8:10 am-2:55 pm

2 stops8h 45m

San Francisco

Tue 3/10

5:40 am-11:40 am

Nonstop4h 00m

$252

ChicagoSan Francisco

ORD - SFO

ORDSFO

Chicago O'Hare Intl

Wed 3/18

9:15 pm-12:16 am

Nonstop5h 01m

San Francisco

Sat 3/21

6:44 pm-12:59 am

Nonstop4h 15m

$257

ChicagoSan Francisco

ORD - SFO

ORDSFO

Chicago O'Hare Intl

Wed 3/4

5:37 pm-11:25 pm

1 stop7h 48m

San Francisco

Tue 3/10

9:46 am-6:05 pm

1 stop6h 19m

$259

ChicagoSan Francisco

MDW - SFO

MDWSFO

Chicago Midway

Wed 3/11

10:05 am-4:30 pm

1 stop8h 25m

San Francisco

Fri 3/13

11:25 pm-5:30 am

Nonstop4h 05m

$260

ChicagoSan Francisco

MDW - SFO

MDWSFO

Chicago Midway

Sat 4/18

2:12 pm-9:22 pm

1 stop9h 10m

San Francisco

Tue 4/28

6:00 am-4:25 pm

1 stop8h 25m

$261

ChicagoSan Francisco

MDW - SFO

MDWSFO

Chicago Midway

Wed 3/18

9:35 am-2:42 pm

1 stop7h 07m

San Francisco

Tue 3/24

10:40 pm-8:53 am

1 stop8h 13m

$261

ChicagoSan Francisco

ORD - SFO

ORDSFO

Chicago O'Hare Intl

Tue 3/31

1:57 pm-7:07 pm

1 stop7h 10m

San Francisco

Wed 4/1

5:50 am-4:43 pm

1 stop8h 53m

$261

IndianapolisSan Francisco

IND - SFO

INDSFO

Indianapolis

Thu 4/9

9:20 am-11:20 am

Nonstop5h 00m

San Francisco

Mon 4/13

11:00 pm-6:36 am

Nonstop4h 36m

$269

ChicagoSan Francisco

MDW - SFO

MDWSFO

Chicago Midway

Mon 4/13

9:45 pm-12:20 am

Nonstop4h 35m

San Francisco

Tue 4/21

11:25 pm-5:40 am

Nonstop4h 15m

$272

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/28

Showing 1-10 of 60 results
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Best time to book a flight from Indiana to San Francisco

Have a flexible travel schedule? Discover the best time to fly to San Francisco from Indiana with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Indiana to San Francisco

What is the cheapest month to book a flight from Indiana to San Francisco?

Currently, April is the cheapest month in which you can book a flight from Indiana to San Francisco (average of $133). Flying from Indiana to San Francisco in December is currently the most expensive (average of $269). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from IN to SFO?

Find hourly flight availability from Indiana to San Francisco. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated January 29, 2026.

One of the essential ways to save on airfare from Indiana to San Francisco is to remain as flexible as possible. Flights that are at noon tend to be the most expensive. A flight in the morning could potentially save you up to 51% on airfare.

What is the cheapest day to fly from Indiana to San Francisco?

Use this chart to determine the cheapest time to fly round-trip from Indiana to San Francisco. Price data was last updated on January 24, 2026.

Travelers seeking maximum savings on their Indiana to San Francisco flight should consider departing on Friday afternoons when fares are most often at their lowest. Sunday at noon flights should be avoided if possible as fares are typically the most expensive at this time.

Related info for your journey

Find useful and relevant information for your journey from Indiana to San Francisco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to San Francisco from Indiana?

    San Francisco (SFO), located 11.8 mi from the city center, is the airport you fly into when you book flights from Indiana to San Francisco.

  • How popular is this Indiana to San Francisco flight route?

    Flights from Indiana to San Francisco have been viewed 35 times in the past calendar month.

  • How long is the flight from Indiana to San Francisco?

    A quick flight from Indiana to San Francisco can take about 5h 01m. United Airlines provides one of the quickest options available for as low as $250. There are 1841 mi between Indiana and San Francisco. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines to fly from Indiana to San Francisco one-way?

    One-way options have recently been found by users for as low as $85 on Frontier. Other airlines that offer cheap prices include Delta from $89 and American Airlines from $114 one-way.

  • What are the most popular routes from Indiana to San Francisco?

    The most popular route from Indiana to San Francisco is Chicago O'Hare Intl - San Francisco. You may also consider Indianapolis - San Francisco or Chicago Midway - San Francisco.

  • What are the most reliable airlines from Indiana to San Francisco?

    Before booking your flight to San Francisco from Indiana, check out the most reliable airlines to get you to your destination on time: Virgin Australia (76%), Air New Zealand (71%), United Airlines( 46%).

  • What are the cheapest flights from Indiana to San Francisco?

    On average you can expect to pay $409 for a flight from Indiana to San Francisco. The cheapest flight overall is $165 while the most popular route, (Chicago O'Hare Intl - San Francisco) is currently priced at $156.

  • Can I find deals for flights from Indiana to San Francisco that include hotel bookings?

    Yes. In addition to deals on Indiana to San Francisco flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Indiana to San Francisco?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Indiana to San Francisco.

  • Can I find deals for business class flights from Indiana to San Francisco?

    Yes. Cheapflights offers flight deals from Indiana to San Francisco by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Indiana to San Francisco?

    Currently, April is the cheapest month in which you can book a flight from Indiana to San Francisco (average of $133). Flying from Indiana to San Francisco in December is currently the most expensive (average of $269). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near San Francisco?

Book flights to San Francisco if you plan to visit one of these locations
South San Francisco
Santa Cruz
Roseville
Santa Clara
Livermore
Watsonville
San Bruno
Daly City
Sunnyvale
Turlock
Vacaville
San Carlos
San Ramon
Manteca
Vallejo
San Lorenzo
Davis
Hollister
Redwood City
Union City

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Indiana to San Francisco

See prices for flight routes from nearby airports that may be better suited for you.
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Top 5 airlines flying from Indiana to San Francisco

Discover the top 5 airlines that operate flights from Indiana to San Francisco. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 29, 2026.
AirlineCheapestAverageFlexibilityOn-time
FrontierCheapest$100Average$250FlexibilityNo cancel feeOn-time62%
DeltaCheapest$165Average$345FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$226Average$419FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$269Average$448FlexibilityNo cancel feeOn-time69%
SouthwestCheapest$284Average$410FlexibilityNo cancel feeOn-time63%

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