HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
San Francisco

$126+ Cheap flights from Florida Keys to San Francisco (SFO)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/19. Fares are subject to change and may not be available on all flights or dates of travel.
EYW — SFO
Jun 23 — Jun 301
Mon 6/23
Mon 6/30
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Florida Keys to San Francisco with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Florida Keys to San Francisco

Keep the following information in mind while searching for Florida Keys to San Francisco flight deals. Data was last updated June 18, 2025.

Round-trip from

$237
(American Airlines)

One-way from

$126
(United Airlines)
From Florida Keys to San Francisco
Search Deals
One-way flight from Florida Keys to San Francisco
Search Deals

Find flight deals from Florida Keys to San Francisco

Cheapest flights from Florida Keys to San Francisco
Explore the most affordable flight options available from Florida Keys to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 18, 2025.

This American Airlines deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/158:23 amMIA - SFO
Nonstop5h 50mAmerican Airlines
Tue 7/228:00 amSFO - MIA
Nonstop5h 40mAmerican Airlines
Deal found 6/16$237
This United Airlines deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/48:45 amMIA - SFO
Nonstop6h 03mUnited Airlines
Mon 7/710:55 pmSFO - MIA
1 stop9h 23mUnited Airlines
Deal found 6/16$239
This Southwest deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/51:45 pmMIA - SFO
1 stop7h 50mSouthwest
Sun 11/99:25 pmSFO - MIA
1 stop10h 30mSouthwest
Deal found 6/17$249
This Delta deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/157:48 amMIA - SFO
1 stop10h 02mDelta
Tue 7/2912:50 amSFO - MIA
1 stop9h 48mDelta
Deal found 6/18$256
This Kiwi.com deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/146:00 amMIA - SFO
1 stop21h 19mFrontier
Sun 7/206:52 pmSFO - MIA
1 stop7h 53mFrontier
Deal found 6/15$292
This American Airlines deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/33:02 pmEYW - SFO
1 stop8h 23mAmerican Airlines
Mon 7/711:17 pmSFO - EYW
1 stop9h 43mAmerican Airlines
Deal found 6/16$314
This Kiwi.com deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/127:15 amMIA - SFO
1 stop7h 59mMultiple Airlines
Tue 7/158:50 pmSFO - MIA
2 stops17h 30mMultiple Airlines
Deal found 6/16$363
This Alaska Airlines deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/266:31 pmMIA - SFO
1 stop19h 01mAlaska Airlines
Mon 9/299:58 pmSFO - MIA
2 stops16h 33mAlaska Airlines
Deal found 6/18$366
This Delta deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/27:10 amEYW - SFO
1 stop10h 03mDelta
Sun 7/66:15 amSFO - EYW
1 stop10h 24mDelta
Deal found 6/17$379
This United Airlines deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/22:12 pmEYW - SFO
3 stops27h 58mUnited Airlines
Sun 7/610:58 pmSFO - EYW
2 stops35h 14mUnited Airlines
Deal found 6/17$895
This KAYAK deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/31:47 pmEYW - SFO
2 stops24h 57mBreeze Airways
Mon 7/712:29 pmSFO - EYW
3 stops41h 53mBreeze Airways
Deal found 6/16$974

Cheapflights Fare Finder

Customize your flight search to find flights from Florida Keys to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 18, 2025.
Use the filters below to find and compare flights from Florida Keys to San Francisco that are best for you.

Fly from

Florida Keys

Fly to

San Francisco

Route

Depart

Return

Price

MiamiSan Francisco

MIA - SFO

MIASFO

Miami

Tue 7/15

8:23 am-11:13 am

Nonstop5h 50m

San Francisco

Tue 7/22

8:00 am-4:40 pm

Nonstop5h 40m

$237

MiamiSan Francisco

MIA - SFO

MIASFO

Miami

Fri 7/4

8:45 am-11:48 am

Nonstop6h 03m

San Francisco

Mon 7/7

10:55 pm-11:18 am

1 stop9h 23m

$239

MiamiSan Francisco

MIA - SFO

MIASFO

Miami

Tue 7/1

6:50 am-12:35 pm

1 stop8h 45m

San Francisco

Fri 7/4

10:45 am-10:00 pm

1 stop8h 15m

$253

MiamiSan Francisco

MIA - SFO

MIASFO

Miami

Tue 7/15

7:48 am-2:50 pm

1 stop10h 02m

San Francisco

Tue 7/29

12:50 am-1:38 pm

1 stop9h 48m

$256

MiamiSan Francisco

MIA - SFO

MIASFO

Miami

Mon 7/14

6:00 am-12:19 am

1 stop21h 19m

San Francisco

Sun 7/20

6:52 pm-5:45 am

1 stop7h 53m

$292

Key WestSan Francisco

EYW - SFO

EYWSFO

Key West

Thu 7/3

3:02 pm-8:25 pm

1 stop8h 23m

San Francisco

Mon 7/7

11:17 pm-12:00 pm

1 stop9h 43m

$314

MiamiSan Francisco

MIA - SFO

MIASFO

Miami

Sat 7/12

7:15 am-12:14 pm

1 stop7h 59m

San Francisco

Tue 7/15

8:50 pm-5:20 pm

2 stops17h 30m

$363

Key WestSan Francisco

EYW - SFO

EYWSFO

Key West

Wed 7/2

7:10 am-2:13 pm

1 stop10h 03m

San Francisco

Sun 7/6

6:15 am-7:39 pm

1 stop10h 24m

$379

MiamiSan Francisco

MIA - SFO

MIASFO

Miami

Wed 9/10

6:31 pm-4:24 pm

2 stops24h 53m

San Francisco

Sun 9/14

9:19 pm-5:31 pm

1 stop17h 12m

$388

Key WestSan Francisco

EYW - SFO

EYWSFO

Key West

Wed 7/2

2:12 pm-3:10 pm

3 stops27h 58m

San Francisco

Sun 7/6

10:58 pm-1:12 pm

2 stops35h 14m

$895

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/16

Showing 1-10 of 22 results
1
2
3

Best time to book a flight from Florida Keys to San Francisco

Have a flexible travel schedule? Discover the best time to fly to San Francisco from Florida Keys with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Florida Keys to San Francisco

What is the cheapest time of day to fly from EOA to SFO?

Find hourly flight availability from Florida Keys to San Francisco. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated June 18, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Florida Keys to San Francisco as you normally would.

Rainfall in San Francisco by month

Plan your trip to San Francisco by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in San Francisco ranges from 0.0 - 4.4 inches per month. January is typically the wettest month, when rainfall can reach 4.4 in. July is typically the driest time to visit San Francisco when rainfall is around 0.0 in.

Temperature in San Francisco by month

Plan your trip to San Francisco by taking into account the average temperature totals by month.

If weather is an important factor for your trip to San Francisco, use this chart to help with planning. For those seeking warmer temperatures, September is the ideal time of year to visit, when temperatures reach an average of 62.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 51.8 F).

Reviews of airlines servicing San Francisco

Get insights into the airlines that provide service to San Francisco. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Francisco. Reviews last updated June 18, 2025.
Get a feel of what it's like to fly with Breeze Airways, Alaska Airlines and Southwest from Florida Keys to San Francisco by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Breeze Airways
8.1
Very good
182 reviews

Boarding

8.4

Entertainment

6.6

Food

6.8

Overall

8.1

Crew

8.8

Comfort

8.2

Reviews

1 / 11
10.0
Excellent

Dena,Dec 2024

LAS - BDL

It was comfortable and the crew was great! A few free snacks offered would be nice!
Breeze Airways
8.1
Very good
182 reviews
Breeze Airways
8.1
Very good
182 reviews

Boarding

8.4

Entertainment

6.6

Food

6.8

Overall

8.1

Crew

8.8

Comfort

8.2

Reviews

1 / 11
10.0
Excellent

Dena,Dec 2024

LAS - BDL

It was comfortable and the crew was great! A few free snacks offered would be nice!
Alaska Airlines
8.0
Very good
10,000 reviews
Breeze Airways
8.1
Very good
182 reviews

Boarding

8.4

Entertainment

6.6

Food

6.8

Overall

8.1

Crew

8.8

Comfort

8.2

Reviews

1 / 11
10.0
Excellent

Dena,Dec 2024

LAS - BDL

It was comfortable and the crew was great! A few free snacks offered would be nice!
Southwest
8.0
Very good
4,280 reviews
Breeze Airways
8.1
Very good
182 reviews

Boarding

8.4

Entertainment

6.6

Food

6.8

Overall

8.1

Crew

8.8

Comfort

8.2

Reviews

1 / 11
10.0
Excellent

Dena,Dec 2024

LAS - BDL

It was comfortable and the crew was great! A few free snacks offered would be nice!
Delta
8.0
Very good
7,964 reviews
Breeze Airways
8.1
Very good
182 reviews

Boarding

8.4

Entertainment

6.6

Food

6.8

Overall

8.1

Crew

8.8

Comfort

8.2

Reviews

1 / 11
10.0
Excellent

Dena,Dec 2024

LAS - BDL

It was comfortable and the crew was great! A few free snacks offered would be nice!
United Airlines
7.4
Good
8,810 reviews
Breeze Airways
8.1
Very good
182 reviews

Boarding

8.4

Entertainment

6.6

Food

6.8

Overall

8.1

Crew

8.8

Comfort

8.2

Reviews

1 / 11
10.0
Excellent

Dena,Dec 2024

LAS - BDL

It was comfortable and the crew was great! A few free snacks offered would be nice!

Related info for your journey

Find useful and relevant information for your journey from Florida Keys to San Francisco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to San Francisco from Florida Keys?

    Most people fly into San Francisco (SFO) if they book a flight to San Francisco from Florida Keys. San Francisco is conveniently located just 11.8 mi from San Francisco’s city center.

  • What are the cheapest airlines to fly from Florida Keys to San Francisco one-way?

    For one-way options, check prices for United Airlines. According to our data, you can fly for as low as $126. Users have also found prices from $132 and $139 on American Airlines and Delta, respectively.

  • Can I find deals for flights from Florida Keys to San Francisco that include hotel bookings?

    Yes. In addition to deals on Florida Keys to San Francisco flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Florida Keys to San Francisco?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Florida Keys to San Francisco.

  • Can I find deals for business class flights from Florida Keys to San Francisco?

    Yes. Cheapflights offers flight deals from Florida Keys to San Francisco by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Florida Keys to San Francisco?

    Currently, January is the cheapest month in which you can book a flight from Florida Keys to San Francisco (average of $276). Flying from Florida Keys to San Francisco in June is currently the most expensive (average of $362). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Florida Keys?

Book flights to Florida Keys if you plan to visit one of these locations
Roseville
Mountain View
South San Francisco
Livermore
Turlock
Santa Cruz
Manteca
Fairfield
Watsonville
Antioch
Hollister
Milpitas
Newark
Hayward
Alameda
Sunnyvale
Daly City
Union City
Campbell
Capitola

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Florida Keys to San Francisco

See prices for flight routes from nearby airports that may be better suited for you.
Miami to Los Angeles flights
Fort Lauderdale to Los Angeles flights
Orlando to Los Angeles flights
Orlando to Las Vegas flights
Tampa to Las Vegas flights
Fort Lauderdale to Las Vegas flights
Tampa to Los Angeles flights
Orlando to San Francisco flights
Orlando to San Diego flights
Fort Lauderdale to Burbank flights
Miami to Las Vegas flights
Miami to San Diego flights
Miami to San Francisco flights
Miami to Ontario flights
Tampa to San Francisco flights
Fort Lauderdale to San Diego flights
Tampa to San Diego flights
Fort Lauderdale to Santa Ana flights
Orlando to Santa Ana flights
Orlando to Ontario flights
Fort Myers to Las Vegas flights
Fort Lauderdale to San Francisco flights
West Palm Beach to Los Angeles flights
West Palm Beach to Las Vegas flights
Miami to Burbank flights
West Palm Beach to San Diego flights
Fort Lauderdale to Ontario flights
Miami to Santa Ana flights
Orlando to Burbank flights
Jacksonville to Las Vegas flights
Tampa to Santa Ana flights
Tampa to Ontario flights
Orlando Sanford Intl to Las Vegas flights
Fort Myers to Fresno flights
Orlando to San Jose flights
Jacksonville to San Francisco flights
Tampa to Burbank flights
Jacksonville to Los Angeles flights
Sarasota to Las Vegas flights
Pensacola to Las Vegas flights
Fort Myers to Los Angeles flights
Pensacola to Los Angeles flights
Orlando to Sacramento flights
Miami to San Jose flights
Fort Lauderdale to Oakland flights
West Palm Beach to Ontario flights
West Palm Beach to San Francisco flights
Fort Myers to San Francisco flights
Orlando to Oakland flights
Gainesville to Las Vegas flights

Top airline flying from Florida Keys to San Francisco

Discover the top airline that operate flights from Florida Keys to San Francisco. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 18, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$313Average$508FlexibilityNo cancel feeOn-time71%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.