$149+ Cheap flights from Durham, NC to San Francisco (SFO)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/1. Fares are subject to change and may not be available on all flights or dates of travel.
RDU — SFO
Apr 28 — Mai 51
Round-trip
1 adult, Economy
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Find cheap flights from Durham to San Francisco with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheapflights Tip: The best prices from Durham to San Francisco are usually found in July or May, booked 38 days in advance, depart on a Thursday or Friday and return on a Wednesday
Cheap flight deals from Durham to San Francisco
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Cheapest flights from Durham to San FranciscoExplore the most affordable flight options available from Durham to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on März 29, 2026.
Explore the most affordable flight options available from Durham to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on März 29, 2026.
This Southwest deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mi 4/291:25 pm
RDU
- SFO
2 stops11h 40m
Southwest
Sa 5/211:05 am
SFO
- RDU
2 stops9h 10m
Southwest
Deal found 3/24![Southwest logo]()
$276
This Kiwi.com deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Di 4/1410:00 am
RDU
- SFO
1 stop16h 25m
Frontier
Di 4/2110:38 pm
SFO
- RDU
2 stops15h 38m
Frontier
Deal found 3/27![Frontier logo]()
$277
This Alaska Airlines deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Di 4/285:48 pm
RDU
- SFO
1 stop8h 13m
Alaska Airlines
So 5/37:15 am
SFO
- RDU
1 stop7h 53m
Alaska Airlines
Deal found 3/26![Alaska Airlines logo]()
$278
This Kiwi.com deal was found by Cheapflights users on 3/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Di 4/286:00 am
RDU
- SFO
1 stop14h 34m
Frontier
Mi 5/612:52 pm
SFO
- RDU
2 stops17h 29m
Frontier
Deal found 3/28![Frontier logo]()
$279
This Frontier deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Do 4/96:47 pm
RDU
- SFO
1 stop8h 41m
Frontier
Di 4/1410:38 pm
SFO
- RDU
1 stop13h 26m
Frontier
Deal found 3/27![Frontier logo]()
$280
This CheapOair deal was found by Cheapflights users on 3/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Di 5/1212:54 pm
RDU
- SFO
1 stop9h 40m
Frontier
Do 5/2112:52 pm
SFO
- RDU
1 stop19h 39m
Frontier
Deal found 3/28![Frontier logo]()
$281
This Kiwi.com deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sa 5/26:16 am
RDU
- SFO
1 stop14h 18m
Frontier
Fr 5/155:25 pm
SFO
- RDU
2 stops15h 06m
Frontier
Deal found 3/25![Frontier logo]()
$282
This Kiwi.com deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mi 4/296:00 am
RDU
- SFO
2 stops18h 39m
Frontier
Mi 5/1311:59 pm
SFO
- RDU
1 stop8h 22m
Frontier
Deal found 3/25![Frontier logo]()
$283
This Frontier deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Do 4/26:47 pm
RDU
- SFO
1 stop8h 36m
Frontier
Mo 4/610:03 pm
SFO
- RDU
1 stop13h 59m
Frontier
Deal found 3/24![Frontier logo]()
$285
This Frontier deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mi 4/296:00 am
RDU
- SFO
1 stop14h 34m
Frontier
Do 5/711:59 pm
SFO
- RDU
1 stop8h 59m
Frontier
Deal found 3/26![Frontier logo]()
$286
This Kiwi.com deal was found by Cheapflights users on 3/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sa 4/259:49 pm
RDU
- SFO
2 stops16h 01m
Frontier
Mo 5/410:38 pm
SFO
- RDU
1 stop10h 21m
Frontier
Deal found 3/28![Frontier logo]()
$287
This Kiwi.com deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Do 4/169:49 pm
RDU
- SFO
1 stop14h 24m
Frontier
Mo 4/2010:38 pm
SFO
- RDU
2 stops15h 18m
Frontier
Deal found 3/27![Frontier logo]()
$288
Best flights from Durham to San FranciscoDiscover carefully curated flight deals from Durham to San Francisco that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated März 29, 2026.
Discover carefully curated flight deals from Durham to San Francisco that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated März 29, 2026.
This Southwest deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mi 5/61:25 pm
RDU
- SFO
2 stops11h 40m
Southwest
Sa 5/911:05 am
SFO
- RDU
2 stops9h 10m
Southwest
Deal found 3/26![Southwest logo]()
$276
This United Airlines deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fr 5/226:35 am
RDU
- SFO
Nonstop5h 42m
United Airlines
So 5/3111:59 pm
SFO
- RDU
Nonstop5h 22m
United Airlines
Deal found 3/27![United Airlines logo]()
$349
This United Airlines deal was found by Cheapflights users on 3/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fr 5/84:26 pm
RDU
- SFO
Nonstop6h 05m
United Airlines
So 5/107:00 am
SFO
- RDU
Nonstop5h 18m
United Airlines
Deal found 3/28![United Airlines logo]()
$349
This Southwest deal was found by Cheapflights users on 3/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Di 5/51:25 pm
RDU
- SFO
2 stops11h 40m
Southwest
Sa 5/911:05 am
SFO
- RDU
2 stops9h 10m
Southwest
Deal found 3/28![Southwest logo]()
$366
This United Airlines deal was found by Cheapflights users on 3/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
So 4/266:05 am
RDU
- SFO
Nonstop6h 04m
United Airlines
So 5/310:42 pm
SFO
- RDU
Nonstop5h 26m
United Airlines
Deal found 3/28![United Airlines logo]()
$349
This Southwest deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mo 7/135:40 pm
RDU
- SFO
2 stops9h 50m
Southwest
Mo 7/2010:10 am
SFO
- RDU
1 stop11h 50m
Southwest
Deal found 3/25![Southwest logo]()
$380
This United Airlines deal was found by Cheapflights users on 3/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sa 5/26:35 pm
RDU
- SFO
Nonstop6h 05m
United Airlines
Mi 5/65:00 am
SFO
- RDU
1 stop7h 55m
United Airlines
Deal found 3/28![United Airlines logo]()
$352
This Southwest deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mo 8/310:05 am
RDU
- SFO
1 stop11h 10m
Southwest
Mo 8/107:45 pm
SFO
- RDU
2 stops11h 05m
Southwest
Deal found 3/24![Southwest logo]()
$404
This United Airlines deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sa 5/234:22 pm
RDU
- SFO
1 stop9h 34m
United Airlines
So 5/3111:59 pm
SFO
- RDU
Nonstop5h 22m
United Airlines
Deal found 3/27![United Airlines logo]()
$385
This United Airlines deal was found by Cheapflights users on 3/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mi 5/276:35 am
RDU
- SFO
Nonstop5h 42m
United Airlines
Sa 6/65:05 am
SFO
- RDU
1 stop9h 22m
United Airlines
Deal found 3/28![United Airlines logo]()
$413
This Southwest deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sa 5/166:10 am
RDU
- SFO
2 stops12h 15m
Southwest
Mo 5/188:50 am
SFO
- RDU
2 stops10h 55m
Southwest
Deal found 3/27![Southwest logo]()
$457
This United Airlines deal was found by Cheapflights users on 3/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fr 4/246:25 pm
RDU
- SFO
Nonstop6h 01m
United Airlines
Sa 5/28:55 am
SFO
- RDU
1 stop10h 03m
United Airlines
Deal found 3/28![United Airlines logo]()
$458
Last-minute flights from Durham to San FranciscoDiscover last-minute flight deals from Durham to San Francisco. Data last updated März 29, 2026 and is based on user searches.
Discover last-minute flight deals from Durham to San Francisco. Data last updated März 29, 2026 and is based on user searches.
This Frontier deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Do 4/26:47 pm
RDU
- SFO
1 stop8h 36m
Frontier
Mo 4/610:03 pm
SFO
- RDU
1 stop13h 59m
Frontier
Deal found 3/24![Frontier logo]()
$285
This Frontier deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Do 4/96:47 pm
RDU
- SFO
1 stop8h 41m
Frontier
Di 4/1410:38 pm
SFO
- RDU
1 stop13h 26m
Frontier
Deal found 3/27![Frontier logo]()
$280
This Kiwi.com deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Di 4/1410:00 am
RDU
- SFO
1 stop16h 25m
Frontier
Di 4/2110:38 pm
SFO
- RDU
2 stops15h 38m
Frontier
Deal found 3/27![Frontier logo]()
$277
This Kiwi.com deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Do 4/169:49 pm
RDU
- SFO
1 stop14h 24m
Frontier
Mo 4/2010:38 pm
SFO
- RDU
2 stops15h 18m
Frontier
Deal found 3/27![Frontier logo]()
$288
This Kiwi.com deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fr 4/248:48 pm
RDU
- SFO
2 stops23h 46m
Frontier
Di 4/2810:38 pm
SFO
- RDU
1 stop13h 26m
Frontier
Deal found 3/26![Frontier logo]()
$281
This Kiwi.com deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fr 4/249:49 pm
RDU
- SFO
1 stop28h 36m
Frontier
Mi 4/297:40 pm
SFO
- RDU
2 stops11h 16m
Frontier
Deal found 3/26![Frontier logo]()
$289
This Kiwi.com deal was found by Cheapflights users on 3/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sa 4/259:49 pm
RDU
- SFO
2 stops16h 01m
Frontier
Mo 5/410:38 pm
SFO
- RDU
1 stop10h 21m
Frontier
Deal found 3/28![Frontier logo]()
$287
This Alaska Airlines deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Di 4/285:48 pm
RDU
- SFO
1 stop8h 13m
Alaska Airlines
So 5/37:15 am
SFO
- RDU
1 stop7h 53m
Alaska Airlines
Deal found 3/26![Alaska Airlines logo]()
$278
This Kiwi.com deal was found by Cheapflights users on 3/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Di 4/286:00 am
RDU
- SFO
1 stop14h 34m
Frontier
Mi 5/612:52 pm
SFO
- RDU
2 stops17h 29m
Frontier
Deal found 3/28![Frontier logo]()
$279
This Southwest deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mi 4/291:25 pm
RDU
- SFO
2 stops11h 40m
Southwest
Sa 5/211:05 am
SFO
- RDU
2 stops9h 10m
Southwest
Deal found 3/24![Southwest logo]()
$276
This Kiwi.com deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mi 4/296:00 am
RDU
- SFO
2 stops18h 39m
Frontier
Mi 5/1311:59 pm
SFO
- RDU
1 stop8h 22m
Frontier
Deal found 3/25![Frontier logo]()
$283
This Frontier deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mi 4/296:00 am
RDU
- SFO
1 stop14h 34m
Frontier
Do 5/711:59 pm
SFO
- RDU
1 stop8h 59m
Frontier
Deal found 3/26![Frontier logo]()
$286
One-way flights from Durham to San FranciscoSearch for one-way flight options from Durham to San Francisco. Find affordable one-way fares based on user searches. Data last updated März 29, 2026.
Search for one-way flight options from Durham to San Francisco. Find affordable one-way fares based on user searches. Data last updated März 29, 2026.
This Alaska Airlines deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fr 5/15:48 pm
RDU
- SFO
1 stop28h 50m
Alaska Airlines
Deal found 3/25![Alaska Airlines logo]()
$149
This Southwest deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sa 6/64:55 pm
RDU
- SFO
2 stops9h 35m
Southwest
Deal found 3/26![Southwest logo]()
$150
This Expedia deal was found by Cheapflights users on 3/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mo 5/1112:26 pm
RDU
- SFO
1 stop14h 57m
Frontier
Deal found 3/28![Frontier logo]()
$151
This Kiwi.com deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Di 4/146:55 pm
RDU
- SFO
1 stop31h 30m
Frontier
Deal found 3/27![Frontier logo]()
$152
This Kiwi.com deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Di 4/147:46 pm
RDU
- SFO
3 stops25h 59m
Multiple Airlines
Deal found 3/24![Multiple Airlines logo]()
$153
This Kiwi.com deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
So 4/2610:38 pm
RDU
- SFO
2 stops28h 49m
Frontier
Deal found 3/26![Frontier logo]()
$154
This Trip.com deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mo 6/228:06 pm
RDU
- SFO
1 stop17h 23m
Frontier
Deal found 3/25![Frontier logo]()
$155
This Kiwi.com deal was found by Cheapflights users on 3/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Do 5/2810:15 pm
RDU
- SFO
2 stops21h 15m
Frontier
Deal found 3/28![Frontier logo]()
$157
This Kiwi.com deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mo 4/2710:51 pm
RDU
- SFO
3 stops22h 54m
Multiple Airlines
Deal found 3/24![Multiple Airlines logo]()
$158
This Kiwi.com deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Do 4/169:49 pm
RDU
- SFO
2 stops26h 24m
Frontier
Deal found 3/27![Frontier logo]()
$159
This Frontier deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Do 4/26:47 pm
RDU
- SFO
1 stop8h 36m
Frontier
Deal found 3/25![Frontier logo]()
$160
Find flight deals from Durham to San Francisco
Keep the following information in mind while searching for Durham to San Francisco flight deals. Data was last updated März 29, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $276 (Southwest) |
One-way from | $149 (Alaska Airlines) |
Popular in | March |
Cheapest in | July |
Average price | $463 |
Cheapflights Fare Finder
Customize your flight search to find flights from Durham to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated März 29, 2026.
Use the filters below to find and compare flights from Durham to San Francisco that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
RaleighSan Francisco
RDU - SFO
RDUSFO
Raleigh-Durham
Mi 5/6
1:25 pm-10:05 pm
2 stops11h 40m
San Francisco
Sa 5/9
11:05 am-11:15 pm
2 stops9h 10m
$276
Quickest round-trip
RaleighSan Francisco
RDU - SFO
RDUSFO
Raleigh-Durham
Fr 5/22
6:35 am-9:17 am
Nonstop5h 42m
San Francisco
So 5/31
11:59 pm-8:21 am
Nonstop5h 22m
$349
RaleighSan Francisco
RDU - SFO
RDUSFO
Raleigh-Durham
Fr 5/8
4:26 pm-7:31 pm
Nonstop6h 05m
San Francisco
So 5/10
7:00 am-3:18 pm
Nonstop5h 18m
$349
RaleighSan Francisco
RDU - SFO
RDUSFO
Raleigh-Durham
So 4/26
6:05 am-9:09 am
Nonstop6h 04m
San Francisco
So 5/3
10:42 pm-7:08 am
Nonstop5h 26m
$349
RaleighSan Francisco
RDU - SFO
RDUSFO
Raleigh-Durham
Sa 5/2
6:35 pm-9:40 pm
Nonstop6h 05m
San Francisco
Mi 5/6
5:00 am-3:55 pm
1 stop7h 55m
$352
RaleighSan Francisco
RDU - SFO
RDUSFO
Raleigh-Durham
Di 5/5
1:25 pm-10:05 pm
2 stops11h 40m
San Francisco
Sa 5/9
11:05 am-11:15 pm
2 stops9h 10m
$366
RaleighSan Francisco
RDU - SFO
RDUSFO
Raleigh-Durham
Mo 7/13
5:40 pm-12:30 am
2 stops9h 50m
San Francisco
Mo 7/20
10:10 am-1:00 am
1 stop11h 50m
$380
RaleighSan Francisco
RDU - SFO
RDUSFO
Raleigh-Durham
Sa 5/23
4:22 pm-10:56 pm
1 stop9h 34m
San Francisco
So 5/31
11:59 pm-8:21 am
Nonstop5h 22m
$385
RaleighSan Francisco
RDU - SFO
RDUSFO
Raleigh-Durham
Mo 8/3
10:05 am-6:15 pm
1 stop11h 10m
San Francisco
Mo 8/10
7:45 pm-9:50 am
2 stops11h 05m
$404
RaleighSan Francisco
RDU - SFO
RDUSFO
Raleigh-Durham
Mi 5/27
6:35 am-9:17 am
Nonstop5h 42m
San Francisco
Sa 6/6
5:05 am-5:27 pm
1 stop9h 22m
$413
Showing 1-10 of 24 resultsSorted by cheapest first
Best time to book a flight from Durham to San Francisco
Have a flexible travel schedule? Discover the best time to fly to San Francisco from Durham with our price prediction graph.
RDU-SFO
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Durham to San Francisco
DU8-SFO
RDU-SFO
How far ahead should I book a flight from Durham to San Francisco?
Use this chart to determine the optimal time to book a round-trip flight from Durham to San Francisco. Price data was last updated on March 13, 2026.
To ensure you get the cheapest price possible for a flight from Durham to San Francisco, you should look to book at least 38 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.
What is the cheapest month to book a flight from Durham to San Francisco?
Currently, April is the cheapest month in which you can book a flight from Durham to San Francisco (average of $152). Flying from Durham to San Francisco in February is currently the most expensive (average of $289). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from DU8 to SFO?
Find hourly flight availability from Durham to San Francisco. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated März 29, 2026.
When flying from Durham to San Francisco, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.
How much does it cost to fly round-trip from Durham to San Francisco?
Reviews of airlines servicing San Francisco
Get insights into the airlines that provide service to San Francisco. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Francisco. Reviews last updated März 29, 2026.
Read through reviews of airlines operating flights from Durham to San Francisco, such as Southwest,Delta, andUnited Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.6
Boarding
8.1
Comfort
8.0
Overall
8.0
Entertainment
7.5
Food
7.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Crew
8.6
Boarding
8.1
Comfort
8.0
Overall
8.0
Entertainment
7.5
Food
7.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Crew
8.6
Boarding
8.1
Comfort
8.0
Overall
8.0
Entertainment
7.5
Food
7.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Crew
8.6
Boarding
8.1
Comfort
8.0
Overall
8.0
Entertainment
7.5
Food
7.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Crew
8.6
Boarding
8.1
Comfort
8.0
Overall
8.0
Entertainment
7.5
Food
7.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Crew
8.6
Boarding
8.1
Comfort
8.0
Overall
8.0
Entertainment
7.5
Food
7.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Related info for your journey
Find useful and relevant information for your journey from Durham to San Francisco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near San Francisco?
Book flights to San Francisco if you plan to visit one of these locationsSouth San Francisco
Santa Cruz
Santa Clara
Livermore
Roseville
Rancho Cordova
San Bruno
Watsonville
San Ramon
Sunnyvale
Vacaville
San Carlos
Turlock
Redwood City
San Lorenzo
Davis
Manteca
Union City
Elk Grove
Rohnert Park
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
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Alternative routes for Durham to San Francisco
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to San Francisco by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Durham to San Francisco by cabin class
Find flights from Durham to San Francisco, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Durham and San Francisco flights
Browse other Durham and San Francisco flight options. Last updated on März 29, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Other flights to San Francisco
Explore flights to San Francisco departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on März 29, 2026.
Durham to San Francisco flights
Consider these flights traveling from Durham to San Francisco.
Top 6 airlines flying from Durham to San Francisco
Discover the top 6 airlines that operate flights from Durham to San Francisco. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated März 29, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$119 | Average$246 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$226 | Average$445 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$229 | Average$388 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$256 | Average$350 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$262 | Average$352 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$281 | Average$394 | FlexibilityNo cancel fee | On-time69% |