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$151+ Cheap flights from Durham, NC to San Francisco (SFO)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/7. Fares are subject to change and may not be available on all flights or dates of travel.
RDU — SFO
Nov 29 — Dec 61
Sat 11/29
Sat 12/6
1 adult, Economy
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Cheapflights Tip: The best prices from Durham to San Francisco are usually found in July or January, booked 46 days in advance, depart on a Thursday or Friday and return on a Wednesday

Find flight deals from Durham to San Francisco

Cheapest flights from Durham to San Francisco
Explore the most affordable flight options available from Durham to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 30, 2025.

This United Airlines deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/126:40 amRDU - SFO
Nonstop6h 05mUnited Airlines
Sun 12/1411:20 pmSFO - RDU
Nonstop5h 02mUnited Airlines
Deal found 10/30$289
This JetBlue deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/105:10 pmRDU - SFO
1 stop9h 49mJetBlue
Tue 12/167:00 amSFO - RDU
1 stop11h 51mJetBlue
Deal found 10/28$291
This Frontier deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/247:36 pmRDU - SFO
1 stop7h 48mFrontier
Wed 12/3111:20 pmSFO - RDU
1 stop9h 40mFrontier
Deal found 10/28$292
This Frontier deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/156:26 pmRDU - SFO
1 stop8h 58mFrontier
Wed 12/2411:20 pmSFO - RDU
1 stop9h 40mFrontier
Deal found 10/28$293
This Kiwi.com deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/108:15 amRDU - SFO
2 stops11h 36mFrontier
Wed 12/3111:20 pmSFO - RDU
1 stop9h 40mFrontier
Deal found 10/30$294
This Kiwi.com deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/156:00 amRDU - SFO
2 stops19h 27mFrontier
Mon 11/1710:23 pmSFO - RDU
1 stop15h 45mFrontier
Deal found 10/29$295
This Kiwi.com deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/145:21 pmRDU - SFO
1 stop9h 53mFrontier
Mon 11/1710:23 pmSFO - RDU
2 stops17h 55mFrontier
Deal found 10/28$297
This United Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/83:05 pmRDU - SFO
1 stop9h 44mUnited Airlines
Mon 12/1511:20 pmSFO - RDU
Nonstop5h 02mUnited Airlines
Deal found 10/28$299
This Kiwi.com deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/156:26 pmRDU - SFO
1 stop8h 58mFrontier
Tue 12/304:07 pmSFO - RDU
1 stop23h 34mFrontier
Deal found 10/30$300
This Kiwi.com deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/156:00 amRDU - SFO
2 stops19h 27mMultiple Airlines
Thu 11/209:03 amSFO - RDU
1 stop9h 16mMultiple Airlines
Deal found 10/27$301
This Priceline deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/36:00 amRDU - SFO
1 stop9h 10mFrontier
Thu 11/61:10 pmSFO - RDU
1 stop7h 45mFrontier
Deal found 10/28$302
This Kiwi.com deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/251:05 pmRDU - SFO
2 stops21h 46mMultiple Airlines
Tue 12/910:10 pmSFO - RDU
1 stop20h 24mMultiple Airlines
Deal found 10/29$303

Cheap flight deals from Durham to San Francisco

Keep the following information in mind while searching for Durham to San Francisco flight deals. Data was last updated October 30, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$289
(United Airlines)

One-way from

$151
(Kiwi.com)

Popular in

March

Cheapest in

July

Average price

$409
Provider with most accurate pricing for Raleigh-Durham-San Francisco flight deals.
Search Deals
Provider most trusted by Cheapflights users for Raleigh-Durham-San Francisco flights.
Search Deals
From Durham to San Francisco
Search Deals
One-way flight from Durham to San Francisco
Search Deals
Highest demand for flights based on searches. 3% potential increase in price ($12 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($5 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in October 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Durham to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 30, 2025.
Use the filters below to find and compare flights from Durham to San Francisco that are best for you.

Fly from

Durham

Fly to

San Francisco

Route

Depart

Return

Price

RaleighSan Francisco

RDU - SFO

RDUSFO

Raleigh-Durham

Wed 11/26

8:45 am-11:54 am

Nonstop6h 09m

San Francisco

Fri 11/28

7:30 am-3:34 pm

Nonstop5h 04m

$289

RaleighSan Francisco

RDU - SFO

RDUSFO

Raleigh-Durham

Wed 1/21

2:40 pm-11:59 pm

1 stop12h 19m

San Francisco

Wed 2/4

10:40 pm-1:50 pm

1 stop12h 10m

$291

RaleighSan Francisco

RDU - SFO

RDUSFO

Raleigh-Durham

Fri 12/5

1:30 pm-8:10 pm

1 stop9h 40m

San Francisco

Fri 12/12

8:15 am-4:20 pm

Nonstop5h 05m

$299

RaleighSan Francisco

RDU - SFO

RDUSFO

Raleigh-Durham

Thu 11/27

6:00 am-11:17 am

1 stop8h 17m

San Francisco

Mon 12/1

10:45 pm-8:51 am

1 stop7h 06m

$309

RaleighSan Francisco

RDU - SFO

RDUSFO

Raleigh-Durham

Tue 1/20

11:05 am-6:05 pm

2 stops10h 00m

San Francisco

Thu 1/22

9:50 am-9:50 pm

1 stop9h 00m

$314

RaleighSan Francisco

RDU - SFO

RDUSFO

Raleigh-Durham

Mon 1/19

4:35 pm-9:55 pm

1 stop8h 20m

San Francisco

Thu 1/22

7:40 am-10:00 pm

2 stops11h 20m

$314

RaleighSan Francisco

RDU - SFO

RDUSFO

Raleigh-Durham

Sat 11/15

6:00 am-10:35 am

1 stop7h 35m

San Francisco

Sun 11/16

12:30 am-10:49 am

1 stop7h 19m

$339

RaleighSan Francisco

RDU - SFO

RDUSFO

Raleigh-Durham

Wed 11/19

5:41 pm-11:23 pm

1 stop8h 42m

San Francisco

Mon 12/1

10:45 pm-8:51 am

1 stop7h 06m

$349

RaleighSan Francisco

RDU - SFO

RDUSFO

Raleigh-Durham

Wed 11/12

5:55 pm-10:44 pm

1 stop7h 49m

San Francisco

Sat 11/15

12:30 pm-10:22 pm

1 stop6h 52m

$369

RaleighSan Francisco

RDU - SFO

RDUSFO

Raleigh-Durham

Sun 12/14

6:40 am-9:45 am

Nonstop6h 05m

San Francisco

Mon 12/29

9:10 pm-5:16 am

Nonstop5h 06m

$389

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/28

Showing 1-10 of 21 results
1
2
3

Best time to book a flight from Durham to San Francisco

Have a flexible travel schedule? Discover the best time to fly to San Francisco from Durham with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Durham to San Francisco

How far ahead should I book a flight from Durham to San Francisco?

Use this chart to determine the optimal time to book a round-trip flight from Durham to San Francisco. Price data was last updated on October 24, 2025.

To ensure you get the cheapest price possible for a flight from Durham to San Francisco, you should look to book at least 46 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.

What is the cheapest month to book a flight from Durham to San Francisco?

Currently, April is the cheapest month in which you can book a flight from Durham to San Francisco (average of $147). Flying from Durham to San Francisco in July is currently the most expensive (average of $261). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DU8 to SFO?

Find hourly flight availability from Durham to San Francisco. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 30, 2025.

When flying from Durham to San Francisco, the time of day you fly usually plays a role in the price. Save by searching for a flight at noon, which can drop the price by up to 56% versus a flight in the evening.

What is the cheapest day to fly from Durham to San Francisco?

Use this chart to determine the cheapest time to fly round-trip from Durham to San Francisco. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Durham to San Francisco flight should consider departing on Thursday afternoons when fares are most often at their lowest. Saturday evenings flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing San Francisco

Get insights into the airlines that provide service to San Francisco. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Francisco. Reviews last updated October 30, 2025.
Read through reviews of airlines operating flights from Durham to San Francisco, such as Southwest, Delta, and United Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,243 reviews

Food

7.0

Crew

8.6

Boarding

8.1

Comfort

8.0

Entertainment

7.5

Overall

8.0

Reviews

1 / 20
8.0
Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.
Southwest
8.0
Very good
4,243 reviews
Southwest
8.0
Very good
4,243 reviews

Food

7.0

Crew

8.6

Boarding

8.1

Comfort

8.0

Entertainment

7.5

Overall

8.0

Reviews

1 / 20
8.0
Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.
Delta
7.9
Good
7,998 reviews
Southwest
8.0
Very good
4,243 reviews

Food

7.0

Crew

8.6

Boarding

8.1

Comfort

8.0

Entertainment

7.5

Overall

8.0

Reviews

1 / 20
8.0
Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.
United Airlines
7.4
Good
8,998 reviews
Southwest
8.0
Very good
4,243 reviews

Food

7.0

Crew

8.6

Boarding

8.1

Comfort

8.0

Entertainment

7.5

Overall

8.0

Reviews

1 / 20
8.0
Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.
American Airlines
7.2
Good
11,035 reviews
Southwest
8.0
Very good
4,243 reviews

Food

7.0

Crew

8.6

Boarding

8.1

Comfort

8.0

Entertainment

7.5

Overall

8.0

Reviews

1 / 20
8.0
Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.
Frontier
5.8
Fair
3,122 reviews
Southwest
8.0
Very good
4,243 reviews

Food

7.0

Crew

8.6

Boarding

8.1

Comfort

8.0

Entertainment

7.5

Overall

8.0

Reviews

1 / 20
8.0
Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.

Related info for your journey

Find useful and relevant information for your journey from Durham to San Francisco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to San Francisco from Durham?

    Located just 11.8 mi from the city center, San Francisco is the airport most travelers will use when flying to San Francisco from Durham. Booking flights from Durham to San Francisco (SFO) should be relatively easy as there are 3 daily inbound flights from Durham from 6 different airlines.

  • How popular is this Durham to San Francisco flight route?

    The Durham to San Francisco flight path was viewed by 23 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • How long is the flight from Durham to San Francisco?

    United Airlines, JetBlue, and Delta can get you from Durham to San Francisco in just under 6h 09m. Your travel time can differ by up to 6h 10m. The distance between Durham and San Francisco is about 2393 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the most reliable airlines from Durham to San Francisco?

    No one likes to see their flight delayed. When booking a flight from Durham to San Francisco consider choosing United Airlines (93%), Virgin Australia (91%) or Air New Zealand (91%) as they are the most reliable in getting you off to your destination on time.

  • What are the cheapest flights from Durham to San Francisco?

    Looking for the cheapest flight from Durham to San Francisco? While on average our users pay $1,106, our data indicates the cheapest price to be $188. The most popular route (Raleigh-Durham - San Francisco), is priced around $183.

  • Can I find deals for flights from Durham to San Francisco that include hotel bookings?

    Yes. In addition to deals on Durham to San Francisco flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Durham to San Francisco?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Durham to San Francisco.

  • Can I find deals for business class flights from Durham to San Francisco?

    Yes. Cheapflights offers flight deals from Durham to San Francisco by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Durham to San Francisco?

    Currently, April is the cheapest month in which you can book a flight from Durham to San Francisco (average of $147). Flying from Durham to San Francisco in July is currently the most expensive (average of $261). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near San Francisco?

Book flights to San Francisco if you plan to visit one of these locations
Roseville
South San Francisco
Santa Cruz
Livermore
Turlock
Watsonville
Sunnyvale
Santa Clara
Antioch
Manteca
Vallejo
Hollister
Vacaville
San Bruno
Foster City
Redwood City
Union City
Fairfield
Burlingame
Lodi

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Alternative routes for Durham to San Francisco

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Top 6 airlines flying from Durham to San Francisco

Discover the top 6 airlines that operate flights from Durham to San Francisco. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 30, 2025.
AirlineCheapestAverageFlexibilityOn-time
JetBlueCheapest$131Average$287FlexibilityNo cancel feeOn-time62%
FrontierCheapest$141Average$244FlexibilityNo cancel feeOn-time62%
American AirlinesCheapest$195Average$474FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$218Average$390FlexibilityNo cancel feeOn-time63%
DeltaCheapest$276Average$347FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$278Average$426FlexibilityNo cancel feeOn-time69%

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