$164+ Cheap flights from Durham, NC to San Francisco (SFO)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/10. Fares are subject to change and may not be available on all flights or dates of travel.
RDU — SFO
Mar 11 — Mar 181
1 adult, Economy
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Find cheap flights from Durham to San Francisco with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheapflights Tip: The best prices from Durham to San Francisco are usually found in July or May, booked 38 days in advance, depart on a Thursday or Friday and return on a Wednesday
Cheap flight deals from Durham to San Francisco
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Best
Last-minute
One-way
Cheapest flights from Durham to San FranciscoExplore the most affordable flight options available from Durham to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 9, 2026.
Explore the most affordable flight options available from Durham to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 9, 2026.
This United Airlines deal was found by Cheapflights users on 2/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/208:45 am
RDU
- SFO
Nonstop6h 17m
United Airlines
Tue 3/2411:20 pm
SFO
- RDU
1 stop7h 14m
United Airlines
Deal found 2/6![United Airlines logo]()
$289
This Frontier deal was found by Cheapflights users on 2/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/176:43 pm
RDU
- SFO
1 stop8h 45m
Frontier
Sun 4/510:23 pm
SFO
- RDU
1 stop7h 23m
Frontier
Deal found 2/7![Frontier logo]()
$290
This Kiwi.com deal was found by Cheapflights users on 2/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/16:09 pm
RDU
- SFO
2 stops30h 30m
Frontier
Sat 3/710:38 pm
SFO
- RDU
1 stop21h 33m
Frontier
Deal found 2/5![Frontier logo]()
$291
This CheapOair deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/26:15 am
RDU
- SFO
2 stops31h 55m
Multiple Airlines
Wed 3/47:35 am
SFO
- RDU
1 stop29h 25m
Multiple Airlines
Deal found 2/8![Multiple Airlines logo]()
$292
This Kiwi.com deal was found by Cheapflights users on 2/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/1910:47 am
RDU
- SFO
2 stops16h 41m
Frontier
Sun 2/2210:46 pm
SFO
- RDU
1 stop14h 29m
Frontier
Deal found 2/7![Frontier logo]()
$293
This Kiwi.com deal was found by Cheapflights users on 2/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/194:07 pm
RDU
- SFO
2 stops27h 14m
Multiple Airlines
Mon 3/2310:38 pm
SFO
- RDU
1 stop13h 39m
Multiple Airlines
Deal found 2/7![Multiple Airlines logo]()
$294
This CheapOair deal was found by Cheapflights users on 2/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/203:08 pm
RDU
- SFO
1 stop12h 46m
JetBlue
Wed 5/279:00 pm
SFO
- RDU
1 stop17h 00m
JetBlue
Deal found 2/6![JetBlue logo]()
$295
This Kiwi.com deal was found by Cheapflights users on 2/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/36:25 am
RDU
- SFO
2 stops14h 55m
Frontier
Fri 3/1310:38 pm
SFO
- RDU
1 stop31h 04m
Frontier
Deal found 2/5![Frontier logo]()
$296
This Kiwi.com deal was found by Cheapflights users on 2/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/196:25 am
RDU
- SFO
1 stop18h 14m
Frontier
Fri 2/2710:34 pm
SFO
- RDU
2 stops19h 06m
Frontier
Deal found 2/6![Frontier logo]()
$297
This United Airlines deal was found by Cheapflights users on 2/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/206:35 pm
RDU
- SFO
Nonstop6h 05m
United Airlines
Tue 5/2611:59 pm
SFO
- RDU
Nonstop5h 24m
United Airlines
Deal found 2/6![United Airlines logo]()
$298
This Delta deal was found by Cheapflights users on 2/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/157:11 pm
RDU
- SFO
1 stop7h 39m
Delta
Sun 5/247:00 am
SFO
- RDU
1 stop7h 51m
Delta
Deal found 2/6![Delta logo]()
$299
This Frontier deal was found by Cheapflights users on 2/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/306:22 pm
RDU
- SFO
1 stop9h 06m
Frontier
Wed 4/110:23 pm
SFO
- RDU
1 stop7h 23m
Frontier
Deal found 2/6![Frontier logo]()
$300
Best flights from Durham to San FranciscoDiscover carefully curated flight deals from Durham to San Francisco that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated February 9, 2026.
Discover carefully curated flight deals from Durham to San Francisco that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated February 9, 2026.
This United Airlines deal was found by Cheapflights users on 2/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/16:35 pm
RDU
- SFO
Nonstop6h 05m
United Airlines
Sun 5/311:05 pm
SFO
- RDU
1 stop7h 30m
United Airlines
Deal found 2/5![United Airlines logo]()
$289
This Southwest deal was found by Cheapflights users on 2/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/95:15 pm
RDU
- SFO
1 stop7h 40m
Southwest
Fri 5/159:15 pm
SFO
- RDU
1 stop9h 40m
Southwest
Deal found 2/7![Southwest logo]()
$299
This Delta deal was found by Cheapflights users on 2/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/167:01 pm
RDU
- SFO
1 stop7h 53m
Delta
Sun 4/1910:35 pm
SFO
- RDU
1 stop8h 52m
Delta
Deal found 2/6![Delta logo]()
$299
This United Airlines deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/106:05 am
RDU
- SFO
Nonstop6h 04m
United Airlines
Sun 4/1210:50 pm
SFO
- RDU
1 stop8h 16m
United Airlines
Deal found 2/8![United Airlines logo]()
$289
This Delta deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/37:04 pm
RDU
- SFO
1 stop7h 50m
Delta
Sun 5/109:55 pm
SFO
- RDU
1 stop9h 23m
Delta
Deal found 2/8![Delta logo]()
$299
This United Airlines deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/116:27 pm
RDU
- SFO
Nonstop6h 17m
United Airlines
Mon 3/1611:59 pm
SFO
- RDU
1 stop8h 42m
United Airlines
Deal found 2/8![United Airlines logo]()
$289
This United Airlines deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/317:59 pm
RDU
- SFO
1 stop8h 43m
United Airlines
Thu 8/61:15 pm
SFO
- RDU
1 stop7h 22m
United Airlines
Deal found 2/8![United Airlines logo]()
$299
This United Airlines deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/297:59 pm
RDU
- SFO
1 stop8h 43m
United Airlines
Sat 7/45:00 am
SFO
- RDU
1 stop7h 17m
United Airlines
Deal found 2/8![United Airlines logo]()
$299
This United Airlines deal was found by Cheapflights users on 2/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/206:35 pm
RDU
- SFO
Nonstop6h 05m
United Airlines
Tue 5/2610:45 pm
SFO
- RDU
1 stop8h 52m
United Airlines
Deal found 2/6![United Airlines logo]()
$307
This United Airlines deal was found by Cheapflights users on 2/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/239:40 am
RDU
- SFO
Nonstop5h 42m
United Airlines
Mon 7/2710:45 pm
SFO
- RDU
1 stop8h 52m
United Airlines
Deal found 2/7![United Airlines logo]()
$308
This United Airlines deal was found by Cheapflights users on 2/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/169:40 am
RDU
- SFO
Nonstop5h 42m
United Airlines
Sun 6/2111:59 pm
SFO
- RDU
Nonstop5h 24m
United Airlines
Deal found 2/7![United Airlines logo]()
$309
This United Airlines deal was found by Cheapflights users on 2/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/176:00 am
RDU
- SFO
Nonstop6h 03m
United Airlines
Mon 5/258:47 pm
SFO
- RDU
Nonstop5h 17m
United Airlines
Deal found 2/7![United Airlines logo]()
$309
Last-minute flights from Durham to San FranciscoDiscover last-minute flight deals from Durham to San Francisco. Data last updated February 9, 2026 and is based on user searches.
Discover last-minute flight deals from Durham to San Francisco. Data last updated February 9, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 2/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/1910:47 am
RDU
- SFO
2 stops16h 41m
Frontier
Sun 2/2210:46 pm
SFO
- RDU
1 stop14h 29m
Frontier
Deal found 2/7![Frontier logo]()
$293
This Kiwi.com deal was found by Cheapflights users on 2/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/196:25 am
RDU
- SFO
1 stop18h 14m
Frontier
Fri 2/2710:34 pm
SFO
- RDU
2 stops19h 06m
Frontier
Deal found 2/6![Frontier logo]()
$297
This CheapOair deal was found by Cheapflights users on 2/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/257:00 am
RDU
- SFO
1 stop19h 59m
Multiple Airlines
Thu 2/268:48 am
SFO
- RDU
1 stop26h 03m
Multiple Airlines
Deal found 2/6![Multiple Airlines logo]()
$295
This Delta deal was found by Cheapflights users on 2/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/264:50 pm
RDU
- SFO
1 stop9h 14m
Delta
Tue 3/312:42 pm
SFO
- RDU
1 stop8h 07m
Delta
Deal found 2/6![Delta logo]()
$299
This Kiwi.com deal was found by Cheapflights users on 2/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/16:09 pm
RDU
- SFO
2 stops30h 30m
Frontier
Sat 3/710:38 pm
SFO
- RDU
1 stop21h 33m
Frontier
Deal found 2/5![Frontier logo]()
$291
This CheapOair deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/26:15 am
RDU
- SFO
2 stops31h 55m
Multiple Airlines
Wed 3/47:35 am
SFO
- RDU
1 stop29h 25m
Multiple Airlines
Deal found 2/8![Multiple Airlines logo]()
$292
This United Airlines deal was found by Cheapflights users on 2/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/26:27 pm
RDU
- SFO
Nonstop6h 17m
United Airlines
Sun 3/811:35 pm
SFO
- RDU
Nonstop5h 05m
United Airlines
Deal found 2/6![United Airlines logo]()
$298
This Kiwi.com deal was found by Cheapflights users on 2/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/36:25 am
RDU
- SFO
2 stops14h 55m
Frontier
Fri 3/1310:38 pm
SFO
- RDU
1 stop31h 04m
Frontier
Deal found 2/5![Frontier logo]()
$296
This Frontier deal was found by Cheapflights users on 2/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/176:43 pm
RDU
- SFO
1 stop8h 45m
Frontier
Sun 4/510:23 pm
SFO
- RDU
1 stop7h 23m
Frontier
Deal found 2/7![Frontier logo]()
$290
This Kiwi.com deal was found by Cheapflights users on 2/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/194:07 pm
RDU
- SFO
2 stops27h 14m
Multiple Airlines
Mon 3/2310:38 pm
SFO
- RDU
1 stop13h 39m
Multiple Airlines
Deal found 2/7![Multiple Airlines logo]()
$294
This United Airlines deal was found by Cheapflights users on 2/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/208:45 am
RDU
- SFO
Nonstop6h 17m
United Airlines
Tue 3/2411:20 pm
SFO
- RDU
1 stop7h 14m
United Airlines
Deal found 2/6![United Airlines logo]()
$289
This Frontier deal was found by Cheapflights users on 2/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/306:22 pm
RDU
- SFO
1 stop9h 06m
Frontier
Wed 4/110:23 pm
SFO
- RDU
1 stop7h 23m
Frontier
Deal found 2/6![Frontier logo]()
$300
One-way flights from Durham to San FranciscoSearch for one-way flight options from Durham to San Francisco. Find affordable one-way fares based on user searches. Data last updated February 9, 2026.
Search for one-way flight options from Durham to San Francisco. Find affordable one-way fares based on user searches. Data last updated February 9, 2026.
This Kiwi.com deal was found by Cheapflights users on 2/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/108:55 am
RDU
- SFO
1 stop29h 11m
Multiple Airlines
Deal found 2/6![Multiple Airlines logo]()
$164
This Kiwi.com deal was found by Cheapflights users on 2/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/57:18 pm
RDU
- SFO
2 stops32h 10m
Frontier
Deal found 2/5![Frontier logo]()
$165
This Kiwi.com deal was found by Cheapflights users on 2/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/186:00 am
RDU
- SFO
3 stops13h 52m
Multiple Airlines
Deal found 2/7![Multiple Airlines logo]()
$166
This Kiwi.com deal was found by Cheapflights users on 2/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/186:25 am
RDU
- SFO
2 stops21h 03m
Frontier
Deal found 2/7![Frontier logo]()
$167
This Kiwi.com deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/287:55 pm
RDU
- SFO
1 stop26h 19m
Frontier
Deal found 2/8![Frontier logo]()
$168
This Southwest deal was found by Cheapflights users on 2/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/35:50 pm
RDU
- SFO
1 stop10h 00m
Southwest
Deal found 2/6![Southwest logo]()
$169
This Kiwi.com deal was found by Cheapflights users on 2/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/110:20 am
RDU
- SFO
2 stops17h 03m
Frontier
Deal found 2/7![Frontier logo]()
$170
This Expedia deal was found by Cheapflights users on 2/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/45:00 pm
RDU
- SFO
1 stop10h 54m
JetBlue
Deal found 2/6![JetBlue logo]()
$171
This Kiwi.com deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/226:10 am
RDU
- SFO
1 stop18h 29m
Frontier
Deal found 2/8![Frontier logo]()
$172
This Kiwi.com deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/1610:36 pm
RDU
- SFO
2 stops26h 25m
Frontier
Deal found 2/8![Frontier logo]()
$174
This Kiwi.com deal was found by Cheapflights users on 2/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/125:55 pm
RDU
- SFO
3 stops23h 31m
Multiple Airlines
Deal found 2/6![Multiple Airlines logo]()
$175
Find flight deals from Durham to San Francisco
Keep the following information in mind while searching for Durham to San Francisco flight deals. Data was last updated February 9, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $289 (United Airlines) |
One-way from | $164 (Kiwi.com) |
Popular in | March |
Cheapest in | July |
Average price | $389 |
Cheapflights Fare Finder
Customize your flight search to find flights from Durham to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 9, 2026.
Use the filters below to find and compare flights from Durham to San Francisco that are best for you.
Fly from
Durham
Fly to
San Francisco
Route
Depart
Return
Price
RaleighSan Francisco
RDU - SFO
RDUSFO
Raleigh-Durham
Fri 5/1
6:35 pm-9:40 pm
Nonstop6h 05m
San Francisco
Sun 5/3
11:05 pm-9:35 am
1 stop7h 30m
$289
RaleighSan Francisco
RDU - SFO
RDUSFO
Raleigh-Durham
Fri 4/10
6:05 am-9:09 am
Nonstop6h 04m
San Francisco
Sun 4/12
10:50 pm-10:06 am
1 stop8h 16m
$289
RaleighSan Francisco
RDU - SFO
RDUSFO
Raleigh-Durham
Wed 3/11
6:27 pm-9:44 pm
Nonstop6h 17m
San Francisco
Mon 3/16
11:59 pm-11:41 am
1 stop8h 42m
$289
RaleighSan Francisco
RDU - SFO
RDUSFO
Raleigh-Durham
Sat 5/9
5:15 pm-9:55 pm
1 stop7h 40m
San Francisco
Fri 5/15
9:15 pm-9:55 am
1 stop9h 40m
$299
RaleighSan Francisco
RDU - SFO
RDUSFO
Raleigh-Durham
Thu 4/16
7:01 pm-11:54 pm
1 stop7h 53m
San Francisco
Sun 4/19
10:35 pm-10:27 am
1 stop8h 52m
$299
RaleighSan Francisco
RDU - SFO
RDUSFO
Raleigh-Durham
Sun 5/3
7:04 pm-11:54 pm
1 stop7h 50m
San Francisco
Sun 5/10
9:55 pm-10:18 am
1 stop9h 23m
$299
RaleighSan Francisco
RDU - SFO
RDUSFO
Raleigh-Durham
Fri 7/31
7:59 pm-1:42 am
1 stop8h 43m
San Francisco
Thu 8/6
1:15 pm-11:37 pm
1 stop7h 22m
$299
RaleighSan Francisco
RDU - SFO
RDUSFO
Raleigh-Durham
Mon 6/29
7:59 pm-1:42 am
1 stop8h 43m
San Francisco
Sat 7/4
5:00 am-3:17 pm
1 stop7h 17m
$299
RaleighSan Francisco
RDU - SFO
RDUSFO
Raleigh-Durham
Wed 5/20
6:35 pm-9:40 pm
Nonstop6h 05m
San Francisco
Tue 5/26
10:45 pm-10:37 am
1 stop8h 52m
$307
RaleighSan Francisco
RDU - SFO
RDUSFO
Raleigh-Durham
Thu 7/23
9:40 am-12:22 pm
Nonstop5h 42m
San Francisco
Mon 7/27
10:45 pm-10:37 am
1 stop8h 52m
$308
Showing 1-10 of 23 results
Best time to book a flight from Durham to San Francisco
Have a flexible travel schedule? Discover the best time to fly to San Francisco from Durham with our price prediction graph.
RDU-SFO
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Durham to San Francisco
DU8-SFO
RDU-SFO
How far ahead should I book a flight from Durham to San Francisco?
Use this chart to determine the optimal time to book a round-trip flight from Durham to San Francisco. Price data was last updated on February 6, 2026.
To ensure you get the cheapest price possible for a flight from Durham to San Francisco, you should look to book at least 38 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.
What is the cheapest month to book a flight from Durham to San Francisco?
Currently, April is the cheapest month in which you can book a flight from Durham to San Francisco (average of $156). Flying from Durham to San Francisco in February is currently the most expensive (average of $275). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from DU8 to SFO?
Find hourly flight availability from Durham to San Francisco. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated February 9, 2026.
When flying from Durham to San Francisco, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.
How much does it cost to fly round-trip from Durham to San Francisco?
Reviews of airlines servicing San Francisco
Get insights into the airlines that provide service to San Francisco. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Francisco. Reviews last updated February 9, 2026.
Read through reviews of airlines operating flights from Durham to San Francisco, such as Southwest, Delta, and United Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Boarding
8.1
Comfort
8.0
Entertainment
7.5
Crew
8.6
Food
7.0
Overall
8.0
Reviews
1 / 20
8.0
ExcellentWalter,Aug 2025
OAK - SAN
Boarding
8.1
Comfort
8.0
Entertainment
7.5
Crew
8.6
Food
7.0
Overall
8.0
Reviews
1 / 20
8.0
ExcellentWalter,Aug 2025
OAK - SAN
Boarding
8.1
Comfort
8.0
Entertainment
7.5
Crew
8.6
Food
7.0
Overall
8.0
Reviews
1 / 20
8.0
ExcellentWalter,Aug 2025
OAK - SAN
Boarding
8.1
Comfort
8.0
Entertainment
7.5
Crew
8.6
Food
7.0
Overall
8.0
Reviews
1 / 20
8.0
ExcellentWalter,Aug 2025
OAK - SAN
Boarding
8.1
Comfort
8.0
Entertainment
7.5
Crew
8.6
Food
7.0
Overall
8.0
Reviews
1 / 20
8.0
ExcellentWalter,Aug 2025
OAK - SAN
Boarding
8.1
Comfort
8.0
Entertainment
7.5
Crew
8.6
Food
7.0
Overall
8.0
Reviews
1 / 20
8.0
ExcellentWalter,Aug 2025
OAK - SAN
Related info for your journey
Find useful and relevant information for your journey from Durham to San Francisco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near San Francisco?
Book flights to San Francisco if you plan to visit one of these locationsSouth San Francisco
Santa Cruz
Santa Clara
Roseville
Livermore
Watsonville
San Bruno
Daly City
Sunnyvale
Turlock
Vacaville
San Carlos
San Ramon
San Lorenzo
Davis
Hollister
Redwood City
Manteca
Union City
Elk Grove
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
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Alternative routes for Durham to San Francisco
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to San Francisco by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Durham to San Francisco by cabin class
Find flights from Durham to San Francisco, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Durham and San Francisco flights
Browse other Durham and San Francisco flight options. Last updated on February 9, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Other flights to San Francisco
Explore flights to San Francisco departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on February 9, 2026.
Durham to San Francisco flights
Consider these flights traveling from Durham to San Francisco.
Top 6 airlines flying from Durham to San Francisco
Discover the top 6 airlines that operate flights from Durham to San Francisco. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 9, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$118 | Average$240 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$131 | Average$326 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$216 | Average$484 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$226 | Average$382 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$256 | Average$345 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$278 | Average$409 | FlexibilityNo cancel fee | On-time69% |