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$309+ Cheap flights from Roanoke to San Diego (ROA - SAN)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/18. Fares are subject to change and may not be available on all flights or dates of travel.
ROA — SAN
oct. 11 — oct. 181
sáb. 10/11
sáb. 10/18
1 adult, Economy
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Cheapflights Tip: The best prices from Roanoke to San Diego are usually found in May or September, booked 76 days in advance, depart on a Friday or Wednesday and return on a Friday

Cheap flight deals from Roanoke to San Diego

Discover tips and strategies to find the most affordable flight options for your journey from Roanoke (ROA) to San Diego (SAN). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated septiembre 11, 2025.

Round-trip from

$309
(Delta)

Popular in

June

Cheapest in

May

Average price

$422
From Roanoke to San Diego
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High demand for flights, 2% potential price rise
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Cheapest flight prices on average. 0% potential price decrease ($5 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from Roanoke to San Diego

Cheapest flights from Roanoke to San Diego
Explore the most affordable flight options available from Roanoke to San Diego. Find the lowest fares from popular airlines and budget airlines, with prices last updated on septiembre 11, 2025.

This Delta deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 10/186:00 amROA - SAN
1 stop6h 48mDelta
sáb. 10/252:05 pmSAN - ROA
1 stop7h 04mDelta
Deal found 9/11$309
This American Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 12/1610:09 amROA - SAN
2 stops11h 16mAmerican Airlines
mié. 12/311:13 pmSAN - ROA
1 stop7h 26mAmerican Airlines
Deal found 9/11$314
This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 10/110:30 amROA - SAN
2 stops10h 40mUnited Airlines
sáb. 10/410:46 amSAN - ROA
1 stop7h 55mUnited Airlines
Deal found 9/10$333
This American Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 10/126:00 amROA - SAN
1 stop8h 14mAmerican Airlines
sáb. 10/1812:54 pmSAN - ROA
1 stop8h 05mAmerican Airlines
Deal found 9/9$339
This United Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 10/1810:30 amROA - SAN
1 stop7h 31mUnited Airlines
sáb. 10/256:53 amSAN - ROA
2 stops11h 48mUnited Airlines
Deal found 9/9$353
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 10/182:23 pmROA - SAN
1 stop7h 23mAmerican Airlines
sáb. 10/2510:23 amSAN - ROA
2 stops9h 02mAmerican Airlines
Deal found 9/10$354
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 9/255:00 amROA - SAN
1 stop7h 27mAmerican Airlines
lun. 9/296:22 amSAN - ROA
1 stop11h 08mAmerican Airlines
Deal found 9/10$369
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 12/132:49 pmROA - SAN
1 stop9h 08mAmerican Airlines
vie. 1/210:01 pmSAN - ROA
1 stop7h 41mAmerican Airlines
Deal found 9/10$374
This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 9/225:40 pmROA - SAN
1 stop7h 22mUnited Airlines
jue. 10/212:35 pmSAN - ROA
1 stop7h 49mUnited Airlines
Deal found 9/10$384

Cheapflights Fare Finder

 
Customize your flight search to find flights from Roanoke to San Diego that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated septiembre 11, 2025.
Use the filters below to find and compare flights from Roanoke to San Diego that are best for you.

Fly from

Roanoke

Fly to

San Diego

Route

Depart

Return

Price

RoanokeSan Diego

ROA - SAN

ROASAN

Roanoke

sáb. 10/18

2:23 pm-6:46 pm

1 stop7h 23m

San Diego

sáb. 10/25

1:14 pm-11:37 pm

1 stop7h 23m

$309

RoanokeSan Diego

ROA - SAN

ROASAN

Roanoke

mié. 10/1

6:00 am-9:30 am

1 stop6h 30m

San Diego

sáb. 10/4

2:00 pm-11:57 pm

1 stop6h 57m

$309

RoanokeSan Diego

ROA - SAN

ROASAN

Roanoke

mar. 12/16

6:33 am-12:30 pm

1 stop8h 57m

San Diego

mié. 12/31

1:13 pm-11:39 pm

1 stop7h 26m

$309

RoanokeSan Diego

ROA - SAN

ROASAN

Roanoke

sáb. 10/18

3:42 pm-9:20 pm

1 stop8h 38m

San Diego

sáb. 10/25

2:05 pm-12:09 am

1 stop7h 04m

$309

RoanokeSan Diego

ROA - SAN

ROASAN

Roanoke

sáb. 2/21

3:25 pm-8:56 pm

1 stop8h 31m

San Diego

mié. 2/25

2:00 pm-11:49 pm

1 stop6h 49m

$309

RoanokeSan Diego

ROA - SAN

ROASAN

Roanoke

sáb. 2/28

5:22 am-9:30 am

1 stop7h 08m

San Diego

sáb. 3/7

6:55 am-8:12 pm

1 stop10h 17m

$339

RoanokeSan Diego

ROA - SAN

ROASAN

Roanoke

sáb. 10/18

10:30 am-3:01 pm

1 stop7h 31m

San Diego

sáb. 10/25

6:53 am-9:41 pm

2 stops11h 48m

$353

RoanokeSan Diego

ROA - SAN

ROASAN

Roanoke

jue. 1/1

7:36 am-7:59 pm

1 stop15h 23m

$311

RoanokeSan Diego

ROA - SAN

ROASAN

Roanoke

jue. 1/1

7:55 pm-10:32 pm

2 stops29h 37m

$314

RoanokeSan Diego

ROA - SAN

ROASAN

Roanoke

jue. 1/1

6:00 am-11:57 am

1 stop8h 57m

$343

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/10

Showing 1-10 of 11 results
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Best time to book a flight from Roanoke to San Diego

Have a flexible travel schedule? Discover the best time to fly to San Diego from Roanoke with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Roanoke to San Diego

How far ahead should I book a flight from Roanoke to San Diego?

Use this chart to determine the optimal time to book a round-trip flight from Roanoke to San Diego. Price data was last updated on August 29, 2025.

To ensure you get the cheapest price possible for a flight from Roanoke to San Diego, you should look to book at least 75 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.

What is the cheapest month to book a flight from Roanoke to San Diego?

Currently, August is the cheapest month in which you can book a flight from Roanoke to San Diego (average of $286). Flying from Roanoke to San Diego in March is currently the most expensive (average of $366). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from ROA to SAN?

Find hourly flight availability from Roanoke to San Diego. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated septiembre 11, 2025.

It’s optimal to fly from Roanoke to San Diego in the evening. By choosing this option you can save up to 36% on the cost of your flight, compared to a flight in the afternoon.

Reviews of airlines servicing San Diego

Get insights into the airlines that provide service to San Diego. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Diego. Reviews last updated septiembre 11, 2025.
Read reviews from past customers who have flown Delta, United Airlines, and American Airlines from Roanoke to San Diego. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,960 reviews

Boarding

8.2

Overall

8.0

Entertainment

7.9

Food

7.3

Crew

8.5

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
Delta
8.0
Very good
7,960 reviews
Delta
8.0
Very good
7,960 reviews

Boarding

8.2

Overall

8.0

Entertainment

7.9

Food

7.3

Crew

8.5

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
United Airlines
7.4
Good
8,937 reviews
Delta
8.0
Very good
7,960 reviews

Boarding

8.2

Overall

8.0

Entertainment

7.9

Food

7.3

Crew

8.5

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,960 reviews

Boarding

8.2

Overall

8.0

Entertainment

7.9

Food

7.3

Crew

8.5

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Related info for your journey

Find useful and relevant information for your journey from Roanoke to San Diego. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Roanoke to San Diego?

    For as low as $309, American Airlines can have you in San Diego from Roanoke in 6h 30m. There are 2114 mi between Roanoke and San Diego. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines flying from Roanoke to San Diego round-trip?

    Cheapflights users have booked flights from Roanoke to San Diego round-trip from $278. Other airlines that can offer you cheap pricing are Delta, from $296, and American Airlines, from $308. United Airlines is 41% cheaper than the average price of flights available within the next 90 days to this destination.

  • What are the cheapest airlines to fly from Roanoke to San Diego one-way?

    $311 is the cheapest one-way deal found within the past few days, from American Airlines. You may also be able to find cheap deals on United Airlines and Delta, with prices starting from $314 and $343, respectively.

  • Can I find deals for flights from Roanoke to San Diego that include hotel bookings?

    Yes. In addition to deals on Roanoke to San Diego flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Roanoke to San Diego?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Roanoke to San Diego.

  • Can I find deals for business class flights from Roanoke to San Diego?

    Yes. Cheapflights offers flight deals from Roanoke to San Diego by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Roanoke to San Diego?

    Currently, August is the cheapest month in which you can book a flight from Roanoke to San Diego (average of $286). Flying from Roanoke to San Diego in March is currently the most expensive (average of $366). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near San Diego?

Book flights to San Diego if you plan to visit one of these locations
El Cajon
Chula Vista
La Mesa
Poway
Lemon Grove
Coronado
Imperial Beach
National City
Alpine

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Top 3 airlines flying from Roanoke to San Diego

Discover the top 3 airlines that operate flights from Roanoke to San Diego. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated septiembre 11, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$278Average$438FlexibilityNo cancel feeOn-time69%
DeltaCheapest$296Average$341FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$308Average$496FlexibilityNo cancel feeOn-time71%

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