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$267+ Cheap flights from Roanoke to San Diego (ROA - SAN)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/10. Fares are subject to change and may not be available on all flights or dates of travel.
ROA — SAN
Mar 24 — Mar 311
Tue 3/24
Tue 3/31
1 adult, Economy
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Cheap flight deals from Roanoke to San Diego

Cheapest flights from Roanoke to San Diego
Explore the most affordable flight options available from Roanoke to San Diego. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 22, 2026.

This Delta deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/243:13 pm
ROA
-
SAN
1 stop8h 32m
Delta
Tue 3/3110:30 pm
SAN
-
ROA
1 stop8h 57m
Delta
Deal found 2/20$329
This United Airlines deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/85:40 pm
ROA
-
SAN
1 stop8h 19m
United Airlines
Mon 4/138:37 pm
SAN
-
ROA
2 stops10h 07m
United Airlines
Deal found 2/18$334
This Delta deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/306:00 am
ROA
-
SAN
1 stop9h 50m
Delta
Thu 6/49:30 pm
SAN
-
ROA
1 stop10h 00m
Delta
Deal found 2/19$359
This United Airlines deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/2711:00 am
ROA
-
SAN
1 stop7h 30m
United Airlines
Sat 10/3112:50 pm
SAN
-
ROA
1 stop7h 33m
United Airlines
Deal found 2/19$429
This American Airlines deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/317:50 am
ROA
-
SAN
1 stop17h 50m
American Airlines
Sat 4/46:23 am
SAN
-
ROA
1 stop8h 16m
American Airlines
Deal found 2/20$431
This United Airlines deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/242:55 pm
ROA
-
SAN
1 stop8h 50m
United Airlines
Tue 3/316:20 pm
SAN
-
ROA
2 stops12h 24m
United Airlines
Deal found 2/20$434
This American Airlines deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/282:51 pm
ROA
-
SAN
1 stop9h 16m
American Airlines
Sat 3/76:30 am
SAN
-
ROA
1 stop8h 45m
American Airlines
Deal found 2/20$439
This American Airlines deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/45:00 am
ROA
-
SAN
2 stops10h 03m
American Airlines
Thu 3/266:23 am
SAN
-
ROA
1 stop8h 24m
American Airlines
Deal found 2/20$444
This United Airlines deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/145:40 pm
ROA
-
SAN
1 stop8h 19m
United Airlines
Fri 4/177:14 pm
SAN
-
ROA
2 stops15h 15m
United Airlines
Deal found 2/19$463
This American Airlines deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/77:33 am
ROA
-
SAN
1 stop15h 47m
American Airlines
Wed 3/116:20 am
SAN
-
ROA
1 stop14h 39m
American Airlines
Deal found 2/18$465

Find flight deals from Roanoke to San Diego

Discover tips and strategies to find the most affordable flight options for your journey from Roanoke (ROA) to San Diego (SAN). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated February 22, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$329
(Delta)

One-way from

$267
(Kiwi.com)

Popular in

June

Cheapest in

September

Average price

$478
Provider with most accurate pricing for Roanoke-San Diego flight deals.
Search Deals
Provider most trusted by Cheapflights users for Roanoke-San Diego flights.
Search Deals
From Roanoke to San Diego
Search Deals
One-way flight from Roanoke to San Diego
Search Deals
Highest demand for flights based on searches. 6% potential increase in price ($30 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($5 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in February 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Roanoke to San Diego that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 22, 2026.
Use the filters below to find and compare flights from Roanoke to San Diego that are best for you.

Fly from

Roanoke

Fly to

San Diego

Route

Depart

Return

Price

RoanokeSan Diego

ROA - SAN

ROASAN

Roanoke

Tue 3/24

3:13 pm-8:45 pm

1 stop8h 32m

San Diego

Tue 3/31

9:55 pm-10:27 am

1 stop9h 32m

$329

RoanokeSan Diego

ROA - SAN

ROASAN

Roanoke

Wed 4/8

5:40 pm-10:59 pm

1 stop8h 19m

San Diego

Mon 4/13

10:30 pm-9:44 am

1 stop8h 14m

$329

RoanokeSan Diego

ROA - SAN

ROASAN

Roanoke

Thu 5/28

6:00 am-11:24 am

1 stop8h 24m

San Diego

Tue 6/2

12:49 pm-12:34 am

1 stop8h 45m

$329

RoanokeSan Diego

ROA - SAN

ROASAN

Roanoke

Tue 3/24

10:43 am-7:48 pm

2 stops12h 05m

San Diego

Tue 3/31

10:30 pm-9:44 am

1 stop8h 14m

$434

RoanokeSan Diego

ROA - SAN

ROASAN

Roanoke

Tue 4/14

5:40 pm-10:59 pm

1 stop8h 19m

San Diego

Fri 4/17

7:14 pm-1:29 pm

2 stops15h 15m

$463

RoanokeSan Diego

ROA - SAN

ROASAN

Roanoke

Sun 5/10

8:38 pm-8:04 pm

3 stops50h 26m

$267

RoanokeSan Diego

ROA - SAN

ROASAN

Roanoke

Thu 7/30

8:00 am-7:20 pm

1 stop14h 20m

$322

RoanokeSan Diego

ROA - SAN

ROASAN

Roanoke

Sat 3/7

7:33 am-8:20 pm

1 stop15h 47m

$332

RoanokeSan Diego

ROA - SAN

ROASAN

Roanoke

Mon 5/11

5:42 pm-11:59 pm

2 stops9h 17m

$358

RoanokeSan Diego

ROA - SAN

ROASAN

Roanoke

Thu 7/30

6:40 am-11:54 pm

2 stops20h 14m

$373

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/19

Showing 1-10 of 11 results
1
2

Compare providers for flights from Roanoke to San Diego

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Roanoke to San Diego in February.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Roanoke-San Diego flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Roanoke-San Diego flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Roanoke-San Diego flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Roanoke-San Diego flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Roanoke-San Diego flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Roanoke to San Diego

Have a flexible travel schedule? Discover the best time to fly to San Diego from Roanoke with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Roanoke to San Diego

How far ahead should I book a flight from Roanoke to San Diego?

Use this chart to determine the optimal time to book a round-trip flight from Roanoke to San Diego. Price data was last updated on February 20, 2026.

To ensure you get the cheapest price possible for a flight from Roanoke to San Diego, you should look to book at least 75 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.

What is the cheapest month to book a flight from Roanoke to San Diego?

Currently, July is the cheapest month in which you can book a flight from Roanoke to San Diego (average of $162). Flying from Roanoke to San Diego in April is currently the most expensive (average of $307). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing San Diego

Get insights into the airlines that provide service to San Diego. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Diego. Reviews last updated February 22, 2026.
Read reviews from past customers who have flown Delta, United Airlines, and American Airlines from Roanoke to San Diego. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,241 reviews

Comfort

7.9

Entertainment

7.8

Overall

7.9

Crew

8.5

Boarding

8.1

Food

7.2

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
Delta
7.9
Good
8,241 reviews
Delta
7.9
Good
8,241 reviews

Comfort

7.9

Entertainment

7.8

Overall

7.9

Crew

8.5

Boarding

8.1

Food

7.2

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
United Airlines
7.4
Good
9,341 reviews
Delta
7.9
Good
8,241 reviews

Comfort

7.9

Entertainment

7.8

Overall

7.9

Crew

8.5

Boarding

8.1

Food

7.2

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
American Airlines
7.2
Good
11,338 reviews
Delta
7.9
Good
8,241 reviews

Comfort

7.9

Entertainment

7.8

Overall

7.9

Crew

8.5

Boarding

8.1

Food

7.2

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Related info for your journey

Find useful and relevant information for your journey from Roanoke to San Diego. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Roanoke to San Diego?

    For as low as $329, Delta can have you in San Diego from Roanoke in 8h 19m. There are 2114 mi between Roanoke and San Diego. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines flying from Roanoke to San Diego round-trip?

    Cheapflights users have booked flights from Roanoke to San Diego round-trip from $278. Other airlines that can offer you cheap pricing are Delta, from $296, and American Airlines, from $308. United Airlines is 38% cheaper than the average price of flights available within the next 90 days to this destination.

  • Can I find deals for flights from Roanoke to San Diego that include hotel bookings?

    Yes. In addition to deals on Roanoke to San Diego flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Roanoke to San Diego?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Roanoke to San Diego.

  • Can I find deals for business class flights from Roanoke to San Diego?

    Yes. Cheapflights offers flight deals from Roanoke to San Diego by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Roanoke to San Diego?

    Currently, July is the cheapest month in which you can book a flight from Roanoke to San Diego (average of $162). Flying from Roanoke to San Diego in April is currently the most expensive (average of $307). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near San Diego?

Book flights to San Diego if you plan to visit one of these locations
El Cajon
Chula Vista
National City
Coronado
La Mesa
Poway
Julian
Lemon Grove

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Top 3 airlines flying from Roanoke to San Diego

Discover the top 3 airlines that operate flights from Roanoke to San Diego. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 22, 2026.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$278Average$438FlexibilityNo cancel feeOn-time69%
DeltaCheapest$296Average$338FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$308Average$484FlexibilityNo cancel feeOn-time71%

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