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$162+ Cheap flights from Roanoke to San Diego (ROA - SAN)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/14. Fares are subject to change and may not be available on all flights or dates of travel.
ROA — SAN
Nov 28 — Dec 51
Fri 11/28
Fri 12/5
1 adult, Economy
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1. Tell us where you want to go

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Cheapflights Tip: The best prices from Roanoke to San Diego are usually found in September or May, booked 76 days in advance, depart on a Friday or Wednesday and return on a Friday

Cheap flight deals from Roanoke to San Diego

Discover tips and strategies to find the most affordable flight options for your journey from Roanoke (ROA) to San Diego (SAN). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 29, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$309
(Delta)

One-way from

$162
(Kiwi.com)

Popular in

June

Cheapest in

September

Average price

$489
Provider with most accurate pricing for Roanoke-San Diego flight deals.
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Provider most trusted by Cheapflights users for Roanoke-San Diego flights.
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From Roanoke to San Diego
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One-way flight from Roanoke to San Diego
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High demand for flights, 1% potential price rise
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Cheapest flight prices on average. 1% potential price decrease ($5 potential savings vs. average RT price).
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Average for round-trip flights in October 2025
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Find flight deals from Roanoke to San Diego

Cheapest flights from Roanoke to San Diego
Explore the most affordable flight options available from Roanoke to San Diego. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 29, 2025.

This American Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/167:20 amROA - SAN
1 stop7h 32mAmerican Airlines
Wed 12/3110:01 pmSAN - ROA
1 stop7h 41mAmerican Airlines
Deal found 10/28$309
This Delta deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/246:00 amROA - SAN
1 stop10h 03mDelta
Thu 11/2711:02 amSAN - ROA
1 stop6h 39mDelta
Deal found 10/26$339
This Delta deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/266:00 amROA - SAN
1 stop10h 03mDelta
Tue 12/210:30 pmSAN - ROA
1 stop9h 10mDelta
Deal found 10/29$349
This United Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/156:20 amROA - SAN
2 stops12h 42mUnited Airlines
Thu 11/2010:00 pmSAN - ROA
1 stop8h 47mUnited Airlines
Deal found 10/28$354
This Delta deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/196:00 amROA - SAN
2 stops15h 11mDelta
Thu 11/2711:02 amSAN - ROA
1 stop6h 39mDelta
Deal found 10/26$361
This American Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/117:00 amROA - SAN
1 stop8h 33mAmerican Airlines
Sat 11/159:54 pmSAN - ROA
1 stop9h 37mAmerican Airlines
Deal found 10/27$369
This Delta deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/233:50 pmROA - SAN
1 stop7h 23mDelta
Thu 11/2711:02 amSAN - ROA
1 stop6h 39mDelta
Deal found 10/26$374
This United Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/111:25 pmROA - SAN
2 stops9h 27mUnited Airlines
Sat 11/156:45 amSAN - ROA
2 stops8h 58mUnited Airlines
Deal found 10/27$379
This Delta deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/196:00 amROA - SAN
1 stop10h 03mDelta
Tue 11/252:13 pmSAN - ROA
1 stop7h 02mDelta
Deal found 10/29$384

Cheapflights Fare Finder

 
Customize your flight search to find flights from Roanoke to San Diego that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 29, 2025.
Use the filters below to find and compare flights from Roanoke to San Diego that are best for you.

Fly from

Roanoke

Fly to

San Diego

Route

Depart

Return

Price

RoanokeSan Diego

ROA - SAN

ROASAN

Roanoke

Sat 12/6

6:00 am-1:02 pm

1 stop10h 02m

San Diego

Fri 12/12

10:30 pm-10:40 am

1 stop9h 10m

$309

RoanokeSan Diego

ROA - SAN

ROASAN

Roanoke

Tue 12/16

7:20 am-11:52 am

1 stop7h 32m

San Diego

Wed 12/31

10:01 pm-8:42 am

1 stop7h 41m

$309

RoanokeSan Diego

ROA - SAN

ROASAN

Roanoke

Thu 12/4

3:50 pm-9:18 pm

1 stop8h 28m

San Diego

Wed 12/10

2:19 pm-12:11 am

1 stop6h 52m

$309

RoanokeSan Diego

ROA - SAN

ROASAN

Roanoke

Wed 11/19

6:00 am-1:03 pm

1 stop10h 03m

San Diego

Thu 11/27

11:02 am-8:41 pm

1 stop6h 39m

$309

RoanokeSan Diego

ROA - SAN

ROASAN

Roanoke

Thu 3/5

10:47 am-7:48 pm

2 stops12h 01m

San Diego

Wed 3/11

8:35 am-6:38 pm

1 stop7h 03m

$334

RoanokeSan Diego

ROA - SAN

ROASAN

Roanoke

Sat 2/28

6:00 am-11:21 am

1 stop8h 21m

San Diego

Sat 3/7

6:35 am-5:36 pm

1 stop8h 01m

$339

RoanokeSan Diego

ROA - SAN

ROASAN

Roanoke

Wed 11/19

6:00 am-1:03 pm

1 stop10h 03m

San Diego

Wed 11/26

2:13 pm-12:15 am

1 stop7h 02m

$349

RoanokeSan Diego

ROA - SAN

ROASAN

Roanoke

Mon 12/8

3:50 pm-9:18 pm

1 stop8h 28m

San Diego

Sun 12/14

10:30 pm-10:40 am

1 stop9h 10m

$349

RoanokeSan Diego

ROA - SAN

ROASAN

Roanoke

Sat 11/15

6:20 am-4:02 pm

2 stops12h 42m

San Diego

Thu 11/20

10:00 pm-9:47 am

1 stop8h 47m

$354

RoanokeSan Diego

ROA - SAN

ROASAN

Roanoke

Sun 11/23

3:50 pm-8:13 pm

1 stop7h 23m

San Diego

Thu 11/27

11:02 am-8:41 pm

1 stop6h 39m

$374

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/28

Showing 1-10 of 18 results
1
2

Compare providers for flights from Roanoke to San Diego

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Roanoke to San Diego in October.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
eDreamsPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Roanoke-San Diego flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Roanoke-San Diego flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Roanoke-San Diego flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Roanoke-San Diego flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Roanoke-San Diego flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Roanoke to San Diego

Have a flexible travel schedule? Discover the best time to fly to San Diego from Roanoke with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Roanoke to San Diego

How far ahead should I book a flight from Roanoke to San Diego?

Use this chart to determine the optimal time to book a round-trip flight from Roanoke to San Diego. Price data was last updated on October 24, 2025.

To ensure you get the cheapest price possible for a flight from Roanoke to San Diego, you should look to book at least 75 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.

What is the cheapest month to book a flight from Roanoke to San Diego?

Currently, July is the cheapest month in which you can book a flight from Roanoke to San Diego (average of $160). Flying from Roanoke to San Diego in January is currently the most expensive (average of $308). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from ROA to SAN?

Find hourly flight availability from Roanoke to San Diego. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 29, 2025.

It’s optimal to fly from Roanoke to San Diego in the evening. By choosing this option you can save up to 35% on the cost of your flight, compared to a flight in the afternoon.

How much does it cost to fly round-trip from Roanoke to San Diego?

Reviews of airlines servicing San Diego

Get insights into the airlines that provide service to San Diego. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Diego. Reviews last updated October 29, 2025.
Read reviews from past customers who have flown Delta, United Airlines, and American Airlines from Roanoke to San Diego. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
7,992 reviews

Boarding

8.2

Crew

8.5

Comfort

7.9

Entertainment

7.9

Overall

7.9

Food

7.3

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
Delta
7.9
Good
7,992 reviews
Delta
7.9
Good
7,992 reviews

Boarding

8.2

Crew

8.5

Comfort

7.9

Entertainment

7.9

Overall

7.9

Food

7.3

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
United Airlines
7.4
Good
8,999 reviews
Delta
7.9
Good
7,992 reviews

Boarding

8.2

Crew

8.5

Comfort

7.9

Entertainment

7.9

Overall

7.9

Food

7.3

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
American Airlines
7.2
Good
11,032 reviews
Delta
7.9
Good
7,992 reviews

Boarding

8.2

Crew

8.5

Comfort

7.9

Entertainment

7.9

Overall

7.9

Food

7.3

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Related info for your journey

Find useful and relevant information for your journey from Roanoke to San Diego. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Roanoke to San Diego?

    For as low as $309, Delta can have you in San Diego from Roanoke in 7h 32m. There are 2114 mi between Roanoke and San Diego. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines flying from Roanoke to San Diego round-trip?

    Cheapflights users have booked flights from Roanoke to San Diego round-trip from $278. Other airlines that can offer you cheap pricing are Delta, from $296, and American Airlines, from $308. United Airlines is 40% cheaper than the average price of flights available within the next 90 days to this destination.

  • Can I find deals for flights from Roanoke to San Diego that include hotel bookings?

    Yes. In addition to deals on Roanoke to San Diego flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Roanoke to San Diego?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Roanoke to San Diego.

  • Can I find deals for business class flights from Roanoke to San Diego?

    Yes. Cheapflights offers flight deals from Roanoke to San Diego by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Roanoke to San Diego?

    Currently, July is the cheapest month in which you can book a flight from Roanoke to San Diego (average of $160). Flying from Roanoke to San Diego in January is currently the most expensive (average of $308). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near San Diego?

Book flights to San Diego if you plan to visit one of these locations
El Cajon
Chula Vista
Coronado
La Mesa
Poway
Lemon Grove
National City

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Top 3 airlines flying from Roanoke to San Diego

Discover the top 3 airlines that operate flights from Roanoke to San Diego. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 29, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$278Average$438FlexibilityNo cancel feeOn-time69%
DeltaCheapest$296Average$336FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$308Average$488FlexibilityNo cancel feeOn-time71%

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