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$194+ Cheap flights from Odessa, TX to San Diego (SAN)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/5. Fares are subject to change and may not be available on all flights or dates of travel.
MAF — SAN
Feb 27 — Mar 61
Fri 2/27
Fri 3/6
1 adult, Economy
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Cheap flight deals from Odessa to San Diego

Cheapest flights from Odessa to San Diego
Explore the most affordable flight options available from Odessa to San Diego. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 28, 2026.

This Southwest deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/126:40 pm
MAF
-
SAN
1 stop5h 50m
Southwest
Wed 3/186:20 am
SAN
-
MAF
1 stop5h 55m
Southwest
Deal found 1/27$329
This Southwest deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/1112:55 pm
MAF
-
SAN
1 stop7h 10m
Southwest
Sun 9/138:15 am
SAN
-
MAF
1 stop7h 25m
Southwest
Deal found 1/27$407
This Southwest deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/211:00 pm
MAF
-
SAN
1 stop11h 15m
Southwest
Thu 5/284:25 pm
SAN
-
MAF
1 stop4h 45m
Southwest
Deal found 1/27$414
This United Airlines deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/92:55 pm
MAF
-
SAN
1 stop9h 01m
United Airlines
Fri 2/139:00 am
SAN
-
MAF
1 stop5h 19m
United Airlines
Deal found 1/26$467
This Southwest deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/92:55 pm
MAF
-
SAN
1 stop6h 55m
Southwest
Fri 2/131:40 pm
SAN
-
MAF
2 stops7h 05m
Southwest
Deal found 1/26$472

Find flight deals from Odessa to San Diego

Keep the following information in mind while searching for Odessa to San Diego flight deals. Data was last updated January 28, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$329
(Southwest)

One-way from

$194
(American Airlines)

Popular in

December

Cheapest in

June

Average price

$376
Provider with most accurate pricing for Midland Intl-San Diego flight deals.
Search Deals
Provider most trusted by Cheapflights users for Midland Intl-San Diego flights.
Search Deals
From Odessa to San Diego
Search Deals
One-way flight from Odessa to San Diego
Search Deals
Highest demand for flights based on searches. 10% potential increase in price ($46 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 4% potential price decrease ($19 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in January 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Odessa to San Diego that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 28, 2026.
Use the filters below to find and compare flights from Odessa to San Diego that are best for you.

Fly from

Odessa

Fly to

San Diego

Route

Depart

Return

Price

MidlandSan Diego

MAF - SAN

MAFSAN

Midland Intl

Thu 3/12

6:40 pm-10:30 pm

1 stop5h 50m

San Diego

Wed 3/18

6:20 am-2:15 pm

1 stop5h 55m

$329

MidlandSan Diego

MAF - SAN

MAFSAN

Midland Intl

Thu 5/21

1:00 pm-10:15 pm

1 stop11h 15m

San Diego

Thu 5/28

4:25 pm-11:10 pm

1 stop4h 45m

$414

MidlandSan Diego

MAF - SAN

MAFSAN

Midland Intl

Mon 2/9

2:55 pm-9:56 pm

1 stop9h 01m

San Diego

Fri 2/13

9:00 am-4:19 pm

1 stop5h 19m

$467

MidlandSan Diego

MAF - SAN

MAFSAN

Midland Intl

Wed 2/11

5:18 pm-10:37 pm

1 stop7h 19m

San Diego

Sun 2/15

1:45 pm-9:44 pm

1 stop5h 59m

$467

MidlandSan Diego

MAF - SAN

MAFSAN

Midland Intl

Mon 2/9

2:55 pm-7:50 pm

1 stop6h 55m

San Diego

Fri 2/13

1:40 pm-10:45 pm

2 stops7h 05m

$472

MidlandSan Diego

MAF - SAN

MAFSAN

Midland Intl

Wed 2/11

11:45 am-5:15 pm

2 stops7h 30m

San Diego

Sun 2/15

1:05 pm-10:35 pm

1 stop7h 30m

$493

MidlandSan Diego

MAF - SAN

MAFSAN

Midland Intl

Sun 4/5

6:40 am-8:53 am

1 stop4h 13m

$194

MidlandSan Diego

MAF - SAN

MAFSAN

Midland Intl

Mon 2/9

4:55 pm-10:50 pm

1 stop7h 55m

$234

MidlandSan Diego

MAF - SAN

MAFSAN

Midland Intl

Mon 2/9

3:30 pm-9:10 pm

2 stops7h 40m

$239

MidlandSan Diego

MAF - SAN

MAFSAN

Midland Intl

Sun 4/5

5:30 am-11:05 am

2 stops7h 35m

$260

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/27

Best time to book a flight from Odessa to San Diego

Have a flexible travel schedule? Discover the best time to fly to San Diego from Odessa with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Odessa to San Diego

What is the cheapest month to book a flight from Odessa to San Diego?

Currently, September is the cheapest month in which you can book a flight from Odessa to San Diego (average of $211). Flying from Odessa to San Diego in December is currently the most expensive (average of $494). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing San Diego

Get insights into the airlines that provide service to San Diego. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Diego. Reviews last updated January 28, 2026.
Read through reviews of airlines operating flights from Odessa to San Diego, such as Southwest and American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,268 reviews

Food

7.0

Entertainment

7.5

Overall

8.0

Crew

8.6

Boarding

8.1

Comfort

8.0

Reviews

1 / 20
8.0
Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.
Southwest
8.0
Very good
4,268 reviews
Southwest
8.0
Very good
4,268 reviews

Food

7.0

Entertainment

7.5

Overall

8.0

Crew

8.6

Boarding

8.1

Comfort

8.0

Reviews

1 / 20
8.0
Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.
American Airlines
7.2
Good
11,198 reviews
Southwest
8.0
Very good
4,268 reviews

Food

7.0

Entertainment

7.5

Overall

8.0

Crew

8.6

Boarding

8.1

Comfort

8.0

Reviews

1 / 20
8.0
Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.

Related info for your journey

Find useful and relevant information for your journey from Odessa to San Diego. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to San Diego from Odessa?

    San Diego (SAN) is the airport you will fly into if you book a flight from Odessa to San Diego. You should not have trouble finding flights to San Diego from Odessa; the airport handles an average of 0 inbound flights from Odessa per day. You should also have plenty of airline options to choose from since 2 airlines have flights to the San Diego airport from Odessa. It is only a 2.6 mi journey from San Diego (SAN) to San Diego’s city center.

  • How long is the flight from Odessa to San Diego?

    Departing from Odessa to San Diego will take you 5h 50m. Airlines will cover a distance of 876 mi.

  • Can I find deals for flights from Odessa to San Diego that include hotel bookings?

    Yes. In addition to deals on Odessa to San Diego flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Odessa to San Diego?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Odessa to San Diego.

  • Can I find deals for business class flights from Odessa to San Diego?

    Yes. Cheapflights offers flight deals from Odessa to San Diego by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Odessa to San Diego?

    Currently, September is the cheapest month in which you can book a flight from Odessa to San Diego (average of $211). Flying from Odessa to San Diego in December is currently the most expensive (average of $494). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near San Diego?

Book flights to San Diego if you plan to visit one of these locations
El Cajon
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Julian
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Top 2 airlines flying from Odessa to San Diego

Discover the top 2 airlines that operate flights from Odessa to San Diego. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 28, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$226Average$373FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$244Average$392FlexibilityNo cancel feeOn-time63%

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