$209+ Cheap flights from Odessa, TX to San Diego (SAN)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/15. Fares are subject to change and may not be available on all flights or dates of travel.
MAF — SAN
Apr 19 — Apr 261
Round-trip
1 adult, Economy
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Best
Last-minute
One-way
Cheapest flights from Odessa to San DiegoExplore the most affordable flight options available from Odessa to San Diego. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 20, 2026.
Explore the most affordable flight options available from Odessa to San Diego. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 20, 2026.
This Southwest deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/46:05 pm
MAF
- SAN
1 stop5h 45m
Southwest
Tue 6/91:10 pm
SAN
- MAF
1 stop6h 50m
Southwest
Deal found 3/16![Southwest logo]()
$365
This United Airlines deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/52:13 pm
MAF
- SAN
1 stop5h 48m
United Airlines
Wed 5/66:32 am
SAN
- MAF
1 stop7h 59m
United Airlines
Deal found 3/16![United Airlines logo]()
$405
This Southwest deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/1710:35 am
MAF
- SAN
1 stop7h 00m
Southwest
Mon 4/2012:40 pm
SAN
- MAF
1 stop7h 05m
Southwest
Deal found 3/15![Southwest logo]()
$407
This United Airlines deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/285:20 pm
MAF
- SAN
1 stop6h 06m
United Airlines
Wed 4/2912:10 pm
SAN
- MAF
1 stop7h 29m
United Airlines
Deal found 3/18![United Airlines logo]()
$415
This Southwest deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/2210:20 am
MAF
- SAN
2 stops7h 30m
Southwest
Mon 8/316:35 am
SAN
- MAF
2 stops13h 35m
Southwest
Deal found 3/15![Southwest logo]()
$417
This Southwest deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/162:35 pm
MAF
- SAN
1 stop9h 15m
Southwest
Mon 7/209:55 pm
SAN
- MAF
2 stops12h 40m
Southwest
Deal found 3/15![Southwest logo]()
$418
This American Airlines deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/316:40 am
MAF
- SAN
1 stop7h 23m
American Airlines
Sat 4/43:38 pm
SAN
- MAF
1 stop6h 31m
American Airlines
Deal found 3/15![American Airlines logo]()
$426
Best flights from Odessa to San DiegoDiscover carefully curated flight deals from Odessa to San Diego that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 20, 2026.
Discover carefully curated flight deals from Odessa to San Diego that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 20, 2026.
This Southwest deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/46:05 pm
MAF
- SAN
1 stop5h 45m
Southwest
Tue 6/91:10 pm
SAN
- MAF
1 stop6h 50m
Southwest
Deal found 3/16![Southwest logo]()
$365
This United Airlines deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/52:13 pm
MAF
- SAN
1 stop5h 48m
United Airlines
Wed 5/66:32 am
SAN
- MAF
1 stop7h 59m
United Airlines
Deal found 3/16![United Airlines logo]()
$405
This Southwest deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/2210:20 am
MAF
- SAN
2 stops6h 55m
Southwest
Mon 8/316:25 am
SAN
- MAF
1 stop8h 30m
Southwest
Deal found 3/15![Southwest logo]()
$412
This United Airlines deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/285:20 pm
MAF
- SAN
1 stop6h 06m
United Airlines
Wed 4/2912:10 pm
SAN
- MAF
1 stop7h 29m
United Airlines
Deal found 3/18![United Airlines logo]()
$415
This Southwest deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/162:35 pm
MAF
- SAN
1 stop9h 15m
Southwest
Mon 7/209:55 pm
SAN
- MAF
2 stops12h 40m
Southwest
Deal found 3/15![Southwest logo]()
$418
This Southwest deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/173:35 pm
MAF
- SAN
2 stops6h 25m
Southwest
Mon 4/2012:05 pm
SAN
- MAF
2 stops7h 40m
Southwest
Deal found 3/15![Southwest logo]()
$427
This Southwest deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/312:55 pm
MAF
- SAN
1 stop8h 05m
Southwest
Sat 4/47:15 am
SAN
- MAF
2 stops6h 25m
Southwest
Deal found 3/15![Southwest logo]()
$462
Last-minute flights from Odessa to San DiegoDiscover last-minute flight deals from Odessa to San Diego. Data last updated March 20, 2026 and is based on user searches.
Discover last-minute flight deals from Odessa to San Diego. Data last updated March 20, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/316:40 am
MAF
- SAN
1 stop7h 23m
American Airlines
Sat 4/43:38 pm
SAN
- MAF
1 stop6h 31m
American Airlines
Deal found 3/15![American Airlines logo]()
$426
This Southwest deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/3110:40 am
MAF
- SAN
1 stop6h 15m
Southwest
Sat 4/47:15 am
SAN
- MAF
2 stops6h 25m
Southwest
Deal found 3/15![Southwest logo]()
$462
This Southwest deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/27:25 am
MAF
- SAN
1 stop8h 45m
Southwest
Mon 4/62:35 pm
SAN
- MAF
1 stop7h 45m
Southwest
Deal found 3/18![Southwest logo]()
$487
This Southwest deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/56:50 am
MAF
- SAN
1 stop5h 20m
Southwest
Mon 4/67:10 am
SAN
- MAF
1 stop5h 35m
Southwest
Deal found 3/18![Southwest logo]()
$498
This Southwest deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/1710:35 am
MAF
- SAN
1 stop7h 00m
Southwest
Mon 4/2012:40 pm
SAN
- MAF
1 stop7h 05m
Southwest
Deal found 3/15![Southwest logo]()
$407
This United Airlines deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/285:20 pm
MAF
- SAN
1 stop6h 06m
United Airlines
Wed 4/2912:10 pm
SAN
- MAF
1 stop7h 29m
United Airlines
Deal found 3/18![United Airlines logo]()
$415
One-way flights from Odessa to San DiegoSearch for one-way flight options from Odessa to San Diego. Find affordable one-way fares based on user searches. Data last updated March 20, 2026.
Search for one-way flight options from Odessa to San Diego. Find affordable one-way fares based on user searches. Data last updated March 20, 2026.
This American Airlines deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/45:00 am
MAF
- SAN
1 stop6h 58m
American Airlines
Deal found 3/16![American Airlines logo]()
$244
This Southwest deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/47:00 am
MAF
- SAN
2 stops6h 50m
Southwest
Deal found 3/16![Southwest logo]()
$249
This American Airlines deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/246:40 am
MAF
- SAN
1 stop4h 13m
American Airlines
Deal found 3/15![American Airlines logo]()
$279
This Southwest deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/2410:40 am
MAF
- SAN
2 stops8h 20m
Southwest
Deal found 3/16![Southwest logo]()
$284
This Southwest deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/231:20 pm
MAF
- SAN
2 stops7h 50m
Southwest
Deal found 3/15![Southwest logo]()
$364
This United Airlines deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/247:00 am
MAF
- SAN
3 stops13h 33m
United Airlines
Deal found 3/17![United Airlines logo]()
$615
This Kiwi.com deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/42:30 pm
MAF
- SAN
3 stops48h 36m
Multiple Airlines
Deal found 3/16![Multiple Airlines logo]()
$1,033
This United Airlines deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/235:00 am
MAF
- SAN
3 stops11h 49m
United Airlines
Deal found 3/15![United Airlines logo]()
$2,003
Find flight deals from Odessa to San Diego
Keep the following information in mind while searching for Odessa to San Diego flight deals. Data was last updated March 20, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $365 (Southwest) |
One-way from | $244 (American Airlines) |
Popular in | December |
Cheapest in | June |
Average price | $483 |
Cheapflights Fare Finder
Customize your flight search to find flights from Odessa to San Diego that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 20, 2026.
Use the filters below to find and compare flights from Odessa to San Diego that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
MidlandSan Diego
MAF - SAN
MAFSAN
Midland Intl
Thu 6/4
6:05 pm-9:50 pm
1 stop5h 45m
San Diego
Tue 6/9
1:10 pm-10:00 pm
1 stop6h 50m
$365
MidlandSan Diego
MAF - SAN
MAFSAN
Midland Intl
Tue 5/5
2:13 pm-6:01 pm
1 stop5h 48m
San Diego
Wed 5/6
6:32 am-4:31 pm
1 stop7h 59m
$405
MidlandSan Diego
MAF - SAN
MAFSAN
Midland Intl
Sat 8/22
10:20 am-3:15 pm
2 stops6h 55m
San Diego
Mon 8/31
6:25 am-4:55 pm
1 stop8h 30m
$412
MidlandSan Diego
MAF - SAN
MAFSAN
Midland Intl
Tue 4/28
5:20 pm-9:26 pm
1 stop6h 06m
San Diego
Wed 4/29
12:10 pm-9:39 pm
1 stop7h 29m
$415
MidlandSan Diego
MAF - SAN
MAFSAN
Midland Intl
Thu 7/16
2:35 pm-9:50 pm
1 stop9h 15m
San Diego
Mon 7/20
9:55 pm-12:35 pm
2 stops12h 40m
$418
MidlandSan Diego
MAF - SAN
MAFSAN
Midland Intl
Fri 4/17
3:35 pm-8:00 pm
2 stops6h 25m
San Diego
Mon 4/20
12:05 pm-9:45 pm
2 stops7h 40m
$427
MidlandSan Diego
MAF - SAN
MAFSAN
Midland Intl
Tue 3/31
2:55 pm-9:00 pm
1 stop8h 05m
San Diego
Sat 4/4
7:15 am-3:40 pm
2 stops6h 25m
$462
Cheapest one-way
MidlandSan Diego
MAF - SAN
MAFSAN
Midland Intl
Sat 8/15
10:20 am-3:15 pm
2 stops6h 55m
$209
Quickest one-way
MidlandSan Diego
MAF - SAN
MAFSAN
Midland Intl
Tue 3/24
6:40 am-8:53 am
1 stop4h 13m
$279
MidlandSan Diego
MAF - SAN
MAFSAN
Midland Intl
Tue 3/24
10:40 am-5:00 pm
2 stops8h 20m
$284
Showing 1-10 of 12 resultsSorted by cheapest first
Best time to book a flight from Odessa to San Diego
Have a flexible travel schedule? Discover the best time to fly to San Diego from Odessa with our price prediction graph.
MAF-SAN
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Odessa to San Diego
OD3-SAN
MAF-SAN
What is the cheapest month to book a flight from Odessa to San Diego?
Currently, September is the cheapest month in which you can book a flight from Odessa to San Diego (average of $211). Flying from Odessa to San Diego in December is currently the most expensive (average of $494). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Odessa to San Diego?
Reviews of airlines servicing San Diego
Get insights into the airlines that provide service to San Diego. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Diego. Reviews last updated March 20, 2026.
Read through reviews of airlines operating flights from Odessa to San Diego, such as Southwest and American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Overall
8.0
Food
7.0
Entertainment
7.5
Boarding
8.1
Crew
8.6
Comfort
8.0
Reviews
1 / 20
8.0
ExcellentWalter,Aug 2025
OAK - SAN
Overall
8.0
Food
7.0
Entertainment
7.5
Boarding
8.1
Crew
8.6
Comfort
8.0
Reviews
1 / 20
8.0
ExcellentWalter,Aug 2025
OAK - SAN
Overall
8.0
Food
7.0
Entertainment
7.5
Boarding
8.1
Crew
8.6
Comfort
8.0
Reviews
1 / 20
8.0
ExcellentWalter,Aug 2025
OAK - SAN
Related info for your journey
Find useful and relevant information for your journey from Odessa to San Diego. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near San Diego?
Book flights to San Diego if you plan to visit one of these locationsEl Cajon
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Odessa and San Diego flights
Browse other Odessa and San Diego flight options. Last updated on March 20, 2026.
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Odessa to San Diego flights
Consider these flights traveling from Odessa to San Diego.
Top 2 airlines flying from Odessa to San Diego
Discover the top 2 airlines that operate flights from Odessa to San Diego. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 20, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$226 | Average$373 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$244 | Average$362 | FlexibilityNo cancel fee | On-time63% |