$159+ Cheap flights from San Diego (SAN) to Odessa, TX
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/12. Fares are subject to change and may not be available on all flights or dates of travel.
SAN — MAF
Aug 24 — Aug 311
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from San Diego to Odessa with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from San Diego to Odessa
Cheapest
Best
Last-minute
One-way
Cheapest flights from San Diego to OdessaExplore the most affordable flight options available from San Diego to Odessa. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 25, 2026.
Explore the most affordable flight options available from San Diego to Odessa. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 25, 2026.
This Southwest deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/198:35 am
SAN
- MAF
1 stop5h 40m
Southwest
Tue 8/257:20 am
MAF
- SAN
1 stop6h 45m
Southwest
Deal found 7/20![Southwest logo]()
$317
This United Airlines deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/268:00 am
SAN
- MAF
1 stop6h 12m
United Airlines
Tue 9/299:34 am
MAF
- SAN
1 stop5h 43m
United Airlines
Deal found 7/21![United Airlines logo]()
$397
This Southwest deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/106:30 am
SAN
- MAF
1 stop5h 00m
Southwest
Wed 8/127:20 am
MAF
- SAN
1 stop5h 15m
Southwest
Deal found 7/21![Southwest logo]()
$402
This Southwest deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/226:35 am
SAN
- MAF
1 stop5h 30m
Southwest
Sat 12/2610:45 am
MAF
- SAN
1 stop11h 25m
Southwest
Deal found 7/25![Southwest logo]()
$462
Best flights from San Diego to OdessaDiscover carefully curated flight deals from San Diego to Odessa that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 25, 2026.
Discover carefully curated flight deals from San Diego to Odessa that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 25, 2026.
This Southwest deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/1911:30 am
SAN
- MAF
2 stops7h 00m
Southwest
Tue 8/252:20 pm
MAF
- SAN
2 stops7h 30m
Southwest
Deal found 7/20![Southwest logo]()
$327
This United Airlines deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/268:00 am
SAN
- MAF
1 stop6h 12m
United Airlines
Tue 9/299:34 am
MAF
- SAN
1 stop5h 43m
United Airlines
Deal found 7/20![United Airlines logo]()
$397
This Southwest deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/102:05 pm
SAN
- MAF
2 stops7h 30m
Southwest
Wed 8/127:20 am
MAF
- SAN
1 stop6h 45m
Southwest
Deal found 7/21![Southwest logo]()
$407
Last-minute flights from San Diego to OdessaDiscover last-minute flight deals from San Diego to Odessa. Data last updated July 25, 2026 and is based on user searches.
Discover last-minute flight deals from San Diego to Odessa. Data last updated July 25, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/57:15 am
SAN
- MAF
1 stop7h 45m
American Airlines
Sun 8/96:26 pm
MAF
- SAN
1 stop7h 33m
American Airlines
Deal found 7/21![American Airlines logo]()
$487
This Southwest deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/58:05 am
SAN
- MAF
2 stops7h 30m
Southwest
Sun 8/96:00 am
MAF
- SAN
2 stops6h 55m
Southwest
Deal found 7/21![Southwest logo]()
$518
This American Airlines deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/74:22 pm
SAN
- MAF
1 stop4h 47m
American Airlines
Tue 8/118:00 am
MAF
- SAN
1 stop5h 57m
American Airlines
Deal found 7/23![American Airlines logo]()
$497
This Southwest deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/76:30 am
SAN
- MAF
1 stop5h 00m
Southwest
Tue 8/113:50 pm
MAF
- SAN
2 stops7h 05m
Southwest
Deal found 7/23![Southwest logo]()
$502
This Southwest deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/106:30 am
SAN
- MAF
1 stop5h 00m
Southwest
Wed 8/127:20 am
MAF
- SAN
1 stop5h 15m
Southwest
Deal found 7/21![Southwest logo]()
$402
This Southwest deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/198:35 am
SAN
- MAF
1 stop5h 40m
Southwest
Tue 8/257:20 am
MAF
- SAN
1 stop6h 45m
Southwest
Deal found 7/20![Southwest logo]()
$317
One-way flights from San Diego to OdessaSearch for one-way flight options from San Diego to Odessa. Find affordable one-way fares based on user searches. Data last updated July 25, 2026.
Search for one-way flight options from San Diego to Odessa. Find affordable one-way fares based on user searches. Data last updated July 25, 2026.
This American Airlines deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/168:00 am
SAN
- MAF
1 stop7h 55m
American Airlines
Deal found 7/22![American Airlines logo]()
$159
This Southwest deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/316:30 am
SAN
- MAF
1 stop5h 00m
Southwest
Deal found 7/24![Southwest logo]()
$163
This Southwest deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/1211:10 am
SAN
- MAF
2 stops7h 20m
Southwest
Deal found 7/21![Southwest logo]()
$176
This American Airlines deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/87:15 am
SAN
- MAF
1 stop7h 45m
American Airlines
Deal found 7/21![American Airlines logo]()
$244
This deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/110:55 am
SAN
- MAF
1 stop7h 29m
United Airlines
Deal found 7/23![United Airlines logo]()
$279
This United Airlines deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/166:15 am
SAN
- MAF
2 stops13h 54m
United Airlines
Deal found 7/24![United Airlines logo]()
$303
This Southwest deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/89:10 am
SAN
- MAF
2 stops8h 30m
Southwest
Deal found 7/21![Southwest logo]()
$339
This American Airlines deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/311:55 pm
SAN
- MAF
1 stop8h 04m
American Airlines
Deal found 7/21![American Airlines logo]()
$389
Find flight deals from San Diego to Odessa
Keep the following information in mind while searching for San Diego to Odessa flight deals. Data was last updated July 25, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $317 (Southwest) |
One-way from | $159 (American Airlines) |
Popular in | November |
Cheapest in | February |
Average price | $341 |
Cheapflights Fare Finder
Customize your flight search to find flights from San Diego to Odessa that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 25, 2026.
Use the filters below to find and compare flights from San Diego to Odessa that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
San DiegoMidland
SAN - MAF
SANMAF
San Diego
Wed 8/19
11:30 am-8:30 pm
2 stops7h 00m
Midland Intl
Tue 8/25
2:20 pm-7:50 pm
2 stops7h 30m
$327
Quickest round-trip
San DiegoMidland
SAN - MAF
SANMAF
San Diego
Sat 9/26
8:00 am-4:12 pm
1 stop6h 12m
Midland Intl
Tue 9/29
9:34 am-1:17 pm
1 stop5h 43m
$397
San DiegoMidland
SAN - MAF
SANMAF
San Diego
Mon 8/10
2:05 pm-11:35 pm
2 stops7h 30m
Midland Intl
Wed 8/12
7:20 am-12:05 pm
1 stop6h 45m
$407
Cheapest one-way
Quickest one-way
San DiegoMidland
SAN - MAF
SANMAF
San Diego
Wed 8/12
4:22 pm-11:09 pm
1 stop4h 47m
$159
San DiegoMidland
SAN - MAF
SANMAF
San Diego
Mon 8/24
3:04 pm-11:44 pm
1 stop6h 40m
$163
San DiegoMidland
SAN - MAF
SANMAF
San Diego
Mon 8/31
6:30 am-1:30 pm
1 stop5h 00m
$163
San DiegoMidland
SAN - MAF
SANMAF
San Diego
Mon 8/24
2:25 pm-11:35 pm
2 stops7h 10m
$168
San DiegoMidland
SAN - MAF
SANMAF
San Diego
Wed 8/12
11:10 am-8:30 pm
2 stops7h 20m
$176
San DiegoMidland
SAN - MAF
SANMAF
San Diego
Sat 8/1
10:55 am-8:24 pm
1 stop7h 29m
$279
San DiegoMidland
SAN - MAF
SANMAF
San Diego
Wed 9/16
6:15 am-10:09 pm
2 stops13h 54m
$303
Showing 1-10 of 11 resultsSorted by cheapest first
Best time to book a flight from San Diego to Odessa
Have a flexible travel schedule? Discover the best time to fly to Odessa from San Diego with our price prediction graph.
SAN-MAF
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from San Diego to Odessa
SAN-OD3
SAN-MAF
No data available for this route at this time. Please check back soon.
Reviews of airlines servicing Odessa
Get insights into the airlines that provide service to Odessa. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Odessa. Reviews last updated July 25, 2026.
Peruse reviews from past customers who have flown with American Airlines from San Diego to Odessa to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Comfort
7.2
Food
6.4
Entertainment
6.8
Boarding
7.5
Overall
7.1
Crew
7.9
Reviews
1 / 20
2.0
MediocreJeremy,Sep 2025
SAN - PHL
Comfort
7.2
Food
6.4
Entertainment
6.8
Boarding
7.5
Overall
7.1
Crew
7.9
Reviews
1 / 20
2.0
MediocreJeremy,Sep 2025
SAN - PHL
Related info for your journey
Find useful and relevant information for your journey from San Diego to Odessa. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
Other flight options
Other flights from San Diego
Popular flights
Top destinations
Alternative routes for San Diego to Odessa
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Odessa by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from San Diego to Odessa by cabin class
Find flights from San Diego to Odessa, based on your preferred cabin class, be it economy, premium economy, business, or first class.
San Diego and Odessa flights
Browse other San Diego and Odessa flight options. Last updated on July 25, 2026.
Other flights from San Diego
Browse through other flights departing from San Diego. Flights are based on user searches made on Cheapflights and were last updated on July 25, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
San Diego to Odessa flights
Consider these flights traveling from San Diego to Odessa.
Top 2 airlines flying from San Diego to Odessa
Discover the top 2 airlines that operate flights from San Diego to Odessa. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 25, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$160 | Average$536 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$233 | Average$303 | FlexibilityNo cancel fee | On-time69% |