$135+ Cheap flights from San Diego (SAN) to Odessa, TX
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/25. Fares are subject to change and may not be available on all flights or dates of travel.
SAN — MAF
Oct 16 — Oct 231
Round-trip
1 adult, Economy
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Find cheap flights from San Diego to Odessa with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from San Diego to Odessa
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Cheapest flights from San Diego to OdessaExplore the most affordable flight options available from San Diego to Odessa. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 16, 2026.
Explore the most affordable flight options available from San Diego to Odessa. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 16, 2026.
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/3111:50 am -
1 stop5h 50m
Sat 11/79:09 am -
1 stop5h 06m
Deal found 9/15![American Airlines logo]()
$269
This Southwest deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/316:35 am -
2 stops8h 25m
Sat 11/710:45 am -
1 stop10h 45m
Deal found 9/15![Southwest logo]()
$280
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/812:20 pm -
1 stop5h 14m
Mon 10/125:00 am -
1 stop5h 24m
Deal found 9/15![American Airlines logo]()
$307
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/93:07 pm -
1 stop6h 52m
Mon 10/125:00 am -
1 stop5h 24m
Deal found 9/15![American Airlines logo]()
$325
This Southwest deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/191:25 pm -
1 stop6h 35m
Fri 11/206:10 pm -
1 stop7h 35m
Deal found 9/16![Southwest logo]()
$388
This Southwest deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/83:30 pm -
1 stop4h 50m
Mon 10/125:50 pm -
2 stops7h 25m
Deal found 9/15![Southwest logo]()
$393
This United Airlines deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/166:45 am -
1 stop7h 45m
Sun 12/207:00 am -
1 stop6h 05m
Deal found 9/12![United Airlines logo]()
$437
This Southwest deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/166:45 am -
2 stops8h 55m
Sun 12/206:50 pm -
1 stop6h 10m
Deal found 9/12![Southwest logo]()
$452
This Southwest deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/211:10 am -
1 stop6h 15m
Fri 10/98:25 pm -
1 stop5h 30m
Deal found 9/12![Southwest logo]()
$456
Best flights from San Diego to OdessaDiscover carefully curated flight deals from San Diego to Odessa that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 16, 2026.
Discover carefully curated flight deals from San Diego to Odessa that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 16, 2026.
This Southwest deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/316:35 am -
2 stops8h 25m
Sat 11/710:45 am -
1 stop10h 45m
Deal found 9/15![Southwest logo]()
$280
This United Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/303:00 pm -
1 stop6h 24m
Sun 10/411:56 am -
1 stop7h 50m
Deal found 9/14![United Airlines logo]()
$517
This Southwest deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/2612:10 pm -
1 stop7h 55m
Thu 2/115:30 am -
1 stop5h 55m
Deal found 9/14![Southwest logo]()
$289
This Southwest deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/191:25 pm -
1 stop6h 35m
Fri 11/206:10 pm -
1 stop7h 35m
Deal found 9/16![Southwest logo]()
$388
This Southwest deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/211:10 am -
1 stop6h 15m
Fri 10/98:25 pm -
1 stop5h 30m
Deal found 9/12![Southwest logo]()
$456
This Southwest deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/166:45 am -
2 stops6h 45m
Sun 12/2010:55 am -
2 stops8h 50m
Deal found 9/12![Southwest logo]()
$507
This Southwest deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/284:50 pm -
1 stop4h 50m
Fri 10/25:30 am -
1 stop5h 50m
Deal found 9/13![Southwest logo]()
$517
This Southwest deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/308:35 am -
1 stop5h 40m
Sun 10/46:15 am -
2 stops7h 35m
Deal found 9/14![Southwest logo]()
$522
Last-minute flights from San Diego to OdessaDiscover last-minute flight deals from San Diego to Odessa. Data last updated September 16, 2026 and is based on user searches.
Discover last-minute flight deals from San Diego to Odessa. Data last updated September 16, 2026 and is based on user searches.
This Southwest deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/284:50 pm -
1 stop4h 50m
Fri 10/25:30 am -
1 stop5h 50m
Deal found 9/13![Southwest logo]()
$517
This Southwest deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/211:10 am -
1 stop6h 15m
Fri 10/98:25 pm -
1 stop5h 30m
Deal found 9/12![Southwest logo]()
$456
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/812:20 pm -
1 stop5h 14m
Mon 10/125:00 am -
1 stop5h 24m
Deal found 9/15![American Airlines logo]()
$307
This Southwest deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/83:30 pm -
1 stop4h 50m
Mon 10/125:50 pm -
2 stops7h 25m
Deal found 9/15![Southwest logo]()
$393
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/93:07 pm -
1 stop6h 52m
Mon 10/125:00 am -
1 stop5h 24m
Deal found 9/15![American Airlines logo]()
$325
This Southwest deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/91:15 pm -
2 stops7h 05m
Mon 10/125:50 pm -
1 stop7h 25m
Deal found 9/15![Southwest logo]()
$482
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/3111:50 am -
1 stop5h 50m
Sat 11/79:09 am -
1 stop5h 06m
Deal found 9/15![American Airlines logo]()
$269
This Southwest deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/316:35 am -
2 stops8h 25m
Sat 11/710:45 am -
1 stop10h 45m
Deal found 9/15![Southwest logo]()
$280
One-way flights from San Diego to OdessaSearch for one-way flight options from San Diego to Odessa. Find affordable one-way fares based on user searches. Data last updated September 16, 2026.
Search for one-way flight options from San Diego to Odessa. Find affordable one-way fares based on user searches. Data last updated September 16, 2026.
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/254:30 pm -
1 stop4h 22m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/14![American Airlines logo]()
$135
This Southwest deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/267:05 am -
2 stops7h 45m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/14![Southwest logo]()
$141
This Southwest deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/253:00 pm -
2 stops6h 45m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/14![Southwest logo]()
$264
This Southwest deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/286:30 am -
1 stop5h 00m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/15![Southwest logo]()
$404
This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/283:30 pm -
3 stops48h 20m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/15![Multiple Airlines logo]()
$1,049
Find flight deals from San Diego to Odessa
Keep the following information in mind while searching for San Diego to Odessa flight deals. Data was last updated September 16, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $269 (American Airlines) |
One-way from | $135 (American Airlines) |
Popular in | November |
Cheapest in | February |
Cheapflights Fare Finder
Customize your flight search to find flights from San Diego to Odessa that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 16, 2026.
Use the filters below to find and compare flights from San Diego to Odessa that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
San DiegoMidland
SAN San Diego - MAF Midland Intl
SANMAF
San Diego
Wed 11/25
4:30 pm-10:52 pm
1 stop4h 22m
Midland Intl
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$135
San DiegoMidland
SAN San Diego - MAF Midland Intl
SANMAF
San Diego
Wed 11/25
3:00 pm-11:45 pm
2 stops6h 45m
Midland Intl
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$264
San DiegoMidland
SAN San Diego - MAF Midland Intl
SANMAF
San Diego
Sat 10/31
6:35 am-5:00 pm
2 stops8h 25m
Midland Intl
Sat 11/7
10:45 am-7:30 pm
1 stop10h 45m
$280
San DiegoMidland
SAN San Diego - MAF Midland Intl
SANMAF
San Diego
Tue 1/26
12:10 pm-10:05 pm
1 stop7h 55m
Midland Intl
Thu 2/11
5:30 am-9:25 am
1 stop5h 55m
$289
San DiegoMidland
SAN San Diego - MAF Midland Intl
SANMAF
San Diego
Thu 11/19
1:25 pm-10:00 pm
1 stop6h 35m
Midland Intl
Fri 11/20
6:10 pm-11:45 pm
1 stop7h 35m
$388
San DiegoMidland
SAN San Diego - MAF Midland Intl
SANMAF
San Diego
Mon 9/28
6:30 am-1:30 pm
1 stop5h 00m
Midland Intl
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$404
San DiegoMidland
SAN San Diego - MAF Midland Intl
SANMAF
San Diego
Fri 10/2
11:10 am-7:25 pm
1 stop6h 15m
Midland Intl
Fri 10/9
8:25 pm-11:55 pm
1 stop5h 30m
$456
San DiegoMidland
SAN San Diego - MAF Midland Intl
SANMAF
San Diego
Wed 12/16
6:45 am-3:30 pm
2 stops6h 45m
Midland Intl
Sun 12/20
10:55 am-5:45 pm
2 stops8h 50m
$507
San DiegoMidland
SAN San Diego - MAF Midland Intl
SANMAF
San Diego
Wed 9/30
3:00 pm-11:24 pm
1 stop6h 24m
Midland Intl
Sun 10/4
11:56 am-5:46 pm
1 stop7h 50m
$517
San DiegoMidland
SAN San Diego - MAF Midland Intl
SANMAF
San Diego
Mon 9/28
4:50 pm-11:40 pm
1 stop4h 50m
Midland Intl
Fri 10/2
5:30 am-9:20 am
1 stop5h 50m
$517
Showing 1-10 of 12 resultsSorted by cheapest first
Best time to book a flight from San Diego to Odessa
Have a flexible travel schedule? Discover the best time to fly to Odessa from San Diego with our price prediction graph.
SAN-MAF
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from San Diego to Odessa
SAN-OD3
SAN-MAF
No data available for this route at this time. Please check back soon.
Reviews of airlines servicing Odessa
Get insights into the airlines that provide service to Odessa. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Odessa. Reviews last updated September 16, 2026.
Peruse reviews from past customers who have flown with American Airlines from San Diego to Odessa to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Comfort
7.2
Overall
7.1
Boarding
7.4
Crew
7.9
Food
6.4
Entertainment
6.8
Reviews
1 / 20
2.0
MediocreJeremy,Sep 2025
SAN - PHL
Comfort
7.2
Overall
7.1
Boarding
7.4
Crew
7.9
Food
6.4
Entertainment
6.8
Reviews
1 / 20
2.0
MediocreJeremy,Sep 2025
SAN - PHL
Related info for your journey
Find useful and relevant information for your journey from San Diego to Odessa. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for San Diego to Odessa
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Complete your trip
Complete your trip to Odessa by adding a car rental and/or hotel reservation to your travel itinerary.
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San Diego and Odessa flights
Browse other San Diego and Odessa flight options. Last updated on September 16, 2026.
Other flights from San Diego
Browse through other flights departing from San Diego. Flights are based on user searches made on Cheapflights and were last updated on September 16, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
San Diego to Odessa flights
Consider these flights traveling from San Diego to Odessa.
Top 2 airlines flying from San Diego to Odessa
Discover the top 2 airlines that operate flights from San Diego to Odessa. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 16, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$233 | Average$303 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$296 | Average$536 | FlexibilityNo cancel fee | On-time71% |