$150+ Cheap flights from Louisville to San Diego (SDF - SAN)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/17. Fares are subject to change and may not be available on all flights or dates of travel.
SDF — SAN
Oct 14 — Oct 211
Round-trip
1 adult, Economy
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Find cheap flights from Louisville to San Diego with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Louisville to San Diego
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Cheapest flights from Louisville to San DiegoExplore the most affordable flight options available from Louisville to San Diego. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 14, 2026.
Explore the most affordable flight options available from Louisville to San Diego. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 14, 2026.
This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/265:10 am -
1 stop9h 17m
Thu 12/311:20 am -
1 stop7h 37m
Deal found 9/10![United Airlines logo]()
$321
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/75:19 pm -
1 stop9h 00m
Wed 10/1410:40 pm -
1 stop7h 52m
Deal found 9/10![American Airlines logo]()
$325
This Southwest deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/53:50 pm -
2 stops8h 35m
Thu 12/1010:55 am -
2 stops8h 55m
Deal found 9/10![Southwest logo]()
$331
This American Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/225:04 am -
1 stop7h 06m
Fri 10/237:15 am -
1 stop8h 22m
Deal found 9/9![American Airlines logo]()
$333
This Southwest deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/410:15 am -
2 stops8h 10m
Sat 11/74:30 pm -
2 stops14h 35m
Deal found 9/9![Southwest logo]()
$337
This Southwest deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/223:30 pm -
1 stop11h 25m
Fri 10/2310:15 am -
2 stops7h 55m
Deal found 9/9![Southwest logo]()
$344
This Kiwi.com deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/511:39 am -
2 stops32h 20m
Tue 10/131:22 pm -
1 stop28h 09m
Deal found 9/11![Multiple Airlines logo]()
$345
This Kiwi.com deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/168:47 am -
1 stop12h 51m
Tue 11/171:22 pm -
1 stop23h 04m
Deal found 9/11![Multiple Airlines logo]()
$352
This Kiwi.com deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/114:06 pm -
2 stops10h 51m
Sun 11/1510:56 am -
1 stop29h 23m
Deal found 9/11![Multiple Airlines logo]()
$360
Best flights from Louisville to San DiegoDiscover carefully curated flight deals from Louisville to San Diego that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 14, 2026.
Discover carefully curated flight deals from Louisville to San Diego that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 14, 2026.
This United Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/133:20 pm -
1 stop8h 48m
Tue 2/1612:45 pm -
1 stop6h 12m
Deal found 9/9![United Airlines logo]()
$321
This Southwest deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/223:30 pm -
1 stop11h 25m
Fri 10/2310:15 am -
2 stops7h 55m
Deal found 9/9![Southwest logo]()
$344
This United Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/265:10 am -
2 stops9h 21m
Thu 12/32:26 pm -
1 stop6h 23m
Deal found 9/9![United Airlines logo]()
$326
This Southwest deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/410:15 am -
2 stops8h 10m
Sat 11/74:30 pm -
2 stops14h 35m
Deal found 9/10![Southwest logo]()
$349
This Southwest deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/157:10 am -
1 stop6h 25m
Thu 11/1910:55 am -
2 stops8h 55m
Deal found 9/10![Southwest logo]()
$399
This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2110:25 am -
2 stops12h 43m
Mon 10/2610:30 pm -
1 stop8h 08m
Deal found 9/10![United Airlines logo]()
$426
This Southwest deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/97:50 pm -
1 stop7h 00m
Sun 10/1110:40 pm -
1 stop8h 30m
Deal found 9/9![Southwest logo]()
$406
This United Airlines deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/176:00 am -
1 stop10h 43m
Tue 11/1710:30 pm -
1 stop8h 08m
Deal found 9/12![United Airlines logo]()
$427
This Southwest deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/196:35 am -
2 stops9h 15m
Sat 10/246:30 am -
1 stop9h 00m
Deal found 9/12![Southwest logo]()
$432
This Southwest deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/206:15 am -
2 stops9h 40m
Sun 1/2412:25 pm -
1 stop7h 20m
Deal found 9/12![Southwest logo]()
$462
This Southwest deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/85:35 am -
2 stops14h 15m
Thu 10/1510:40 pm -
1 stop8h 30m
Deal found 9/10![Southwest logo]()
$485
This Southwest deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/196:35 pm -
1 stop6h 50m
Fri 12/256:30 am -
1 stop6h 05m
Deal found 9/12![Southwest logo]()
$487
Last-minute flights from Louisville to San DiegoDiscover last-minute flight deals from Louisville to San Diego. Data last updated September 14, 2026 and is based on user searches.
Discover last-minute flight deals from Louisville to San Diego. Data last updated September 14, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/31:22 pm -
1 stop8h 29m
Wed 10/76:18 am -
1 stop7h 19m
Deal found 9/10![American Airlines logo]()
$321
This Kiwi.com deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/511:39 am -
2 stops32h 20m
Tue 10/131:22 pm -
1 stop28h 09m
Deal found 9/11![Multiple Airlines logo]()
$345
This Kiwi.com deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/511:39 am -
2 stops32h 20m
Thu 10/153:14 pm -
1 stop25h 05m
Deal found 9/11![Multiple Airlines logo]()
$367
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/75:19 pm -
1 stop9h 00m
Wed 10/1410:40 pm -
1 stop7h 52m
Deal found 9/10![American Airlines logo]()
$325
This Southwest deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/97:50 pm -
1 stop7h 00m
Fri 10/1610:15 am -
2 stops7h 55m
Deal found 9/10![Southwest logo]()
$381
This Southwest deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/105:05 pm -
1 stop7h 25m
Thu 10/1510:40 pm -
1 stop8h 30m
Deal found 9/13![Southwest logo]()
$384
This United Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/175:15 am -
1 stop7h 17m
Sat 10/248:45 am -
2 stops8h 46m
Deal found 9/9![United Airlines logo]()
$326
This American Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/225:04 am -
1 stop7h 06m
Fri 10/237:15 am -
1 stop8h 22m
Deal found 9/9![American Airlines logo]()
$333
This Southwest deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/223:30 pm -
1 stop11h 25m
Fri 10/2310:15 am -
2 stops7h 55m
Deal found 9/9![Southwest logo]()
$344
This Southwest deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/305:10 pm -
1 stop10h 05m
Mon 11/23:00 pm -
1 stop5h 40m
Deal found 9/14![Southwest logo]()
$363
One-way flights from Louisville to San DiegoSearch for one-way flight options from Louisville to San Diego. Find affordable one-way fares based on user searches. Data last updated September 14, 2026.
Search for one-way flight options from Louisville to San Diego. Find affordable one-way fares based on user searches. Data last updated September 14, 2026.
This Southwest deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/174:15 pm -
1 stop7h 25m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/13![Southwest logo]()
$150
This Kiwi.com deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/198:47 am -
1 stop31h 29m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/11![Multiple Airlines logo]()
$156
This Southwest deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/35:05 pm -
1 stop7h 20m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/10![Southwest logo]()
$161
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/25:50 pm -
1 stop7h 16m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/10![Delta logo]()
$173
This Southwest deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/27:50 pm -
1 stop6h 55m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/11![Southwest logo]()
$204
This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/211:39 am -
2 stops32h 20m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/10![Multiple Airlines logo]()
$205
This Kiwi.com deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/229:09 pm -
3 stops46h 40m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/9![Multiple Airlines logo]()
$209
This American Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/54:18 pm -
1 stop6h 46m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/13![American Airlines logo]()
$214
This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/310:13 am -
2 stops15h 44m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/10![United Airlines logo]()
$216
This Southwest deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/143:00 pm -
2 stops9h 00m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/11![Southwest logo]()
$219
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/17:54 pm -
1 stop6h 52m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/10![Delta logo]()
$220
Find flight deals from Louisville to San Diego
Discover tips and strategies to find the most affordable flight options for your journey from Louisville (SDF) to San Diego (SAN). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 14, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $299 (American Airlines) |
One-way from | $150 (Southwest) |
Popular in | March |
Cheapest in | February |
Average price | $436 |
Cheapflights Fare Finder
Customize your flight search to find flights from Louisville to San Diego that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 14, 2026.
Use the filters below to find and compare flights from Louisville to San Diego that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
LouisvilleSan Diego
SDF Louisville Intl - SAN San Diego
SDFSAN
Louisville Intl
Tue 11/17
4:15 pm-8:40 pm
1 stop7h 25m
San Diego
Wed 12/31
12:00 am-3:00 am
Nonstop0h 00m
$150
Quickest round-trip
LouisvilleSan Diego
SDF Louisville Intl - SAN San Diego
SDFSAN
Louisville Intl
Sat 10/3
6:00 am-9:45 am
1 stop6h 45m
San Diego
Wed 12/31
12:00 am-3:00 am
Nonstop0h 00m
$161
LouisvilleSan Diego
SDF Louisville Intl - SAN San Diego
SDFSAN
Louisville Intl
Thu 10/22
5:04 am-9:10 am
1 stop7h 06m
San Diego
Wed 12/31
12:00 am-3:00 am
Nonstop0h 00m
$161
LouisvilleSan Diego
SDF Louisville Intl - SAN San Diego
SDFSAN
Louisville Intl
Fri 10/2
7:50 pm-11:45 pm
1 stop6h 55m
San Diego
Wed 12/31
12:00 am-3:00 am
Nonstop0h 00m
$173
LouisvilleSan Diego
SDF Louisville Intl - SAN San Diego
SDFSAN
Louisville Intl
Thu 10/22
9:09 pm-4:49 pm
3 stops46h 40m
San Diego
Wed 12/31
12:00 am-3:00 am
Nonstop0h 00m
$209
LouisvilleSan Diego
SDF Louisville Intl - SAN San Diego
SDFSAN
Louisville Intl
Wed 1/6
10:46 am-2:34 pm
1 stop6h 48m
San Diego
Wed 12/31
12:00 am-3:00 am
Nonstop0h 00m
$214
LouisvilleSan Diego
SDF Louisville Intl - SAN San Diego
SDFSAN
Louisville Intl
Wed 10/7
1:50 pm-8:08 pm
2 stops9h 18m
San Diego
Wed 12/31
12:00 am-3:00 am
Nonstop0h 00m
$216
LouisvilleSan Diego
SDF Louisville Intl - SAN San Diego
SDFSAN
Louisville Intl
Mon 10/5
10:25 am-8:08 pm
2 stops12h 43m
San Diego
Wed 12/31
12:00 am-3:00 am
Nonstop0h 00m
$259
LouisvilleSan Diego
SDF Louisville Intl - SAN San Diego
SDFSAN
Louisville Intl
Sat 10/3
12:55 pm-6:05 pm
2 stops8h 10m
San Diego
Wed 12/31
12:00 am-3:00 am
Nonstop0h 00m
$259
LouisvilleSan Diego
SDF Louisville Intl - SAN San Diego
SDFSAN
Louisville Intl
Fri 10/2
10:25 am-8:08 pm
2 stops12h 43m
San Diego
Wed 12/31
12:00 am-3:00 am
Nonstop0h 00m
$259
Showing 1-10 of 22 resultsSorted by cheapest first
Compare providers for flights from Louisville to San Diego
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Louisville to San Diego in September.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy- | Trust Score*1 star |
- Most accurate provider: When it comes to deals on Louisville-San Diego flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Louisville-San Diego flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Louisville-San Diego flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Louisville-San Diego flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Louisville-San Diego flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Louisville to San Diego
Have a flexible travel schedule? Discover the best time to fly to San Diego from Louisville with our price prediction graph.
SDF-SAN
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Louisville to San Diego
Prices
More
How far ahead should I book a flight from Louisville to San Diego?
Booking 9 days in advance of your planned departure date is, on average, the best time to get cheap flights from Louisville to San Diego. The general trend is that the closer you book to the departure date, the more expensive your flight will be.
What is the cheapest month to book a flight from Louisville to San Diego?
Currently, February is the cheapest month in which you can book a flight from Louisville to San Diego (average of $378). Flying from Louisville to San Diego in March is currently the most expensive (average of $544). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Louisville to San Diego?
Airfare is below average for this route at the moment.
Louisville to San Diego flights typically cost between $376 and $503 in October.The cheapest round-trip price found within the last 5 days was $299 on American Airlines (Oct 10-Oct 17).
What’s the top layover airport for flights from Louisville to San Diego?
Share of 1-stop round-trip flights from Louisville to San Diego chosen by Cheapflights users in the past 12 months, using the same layover each way.
Chicago (ORD) – chosen by Cheapflights users on 50% of 1-stop itineraries from Louisville to San Diego on Cheapflights.
What’s the cheapest layover airport for flights from Louisville to San Diego?
Average round-trip fare for 1-stop flights from Louisville to San Diego, chosen by Cheapflights users in the past 12 months, with the same layover each way.
Dallas (DFW) is the most affordable 1-stop option, with an average round-trip price of $396.
What’s the fastest layover option from Louisville to San Diego?
Shortest average travel time for 1-stop one-way flights from Louisville to San Diego, based on itineraries clicked by Cheapflights users over the past 12 months, grouped by layover airport.
Flights via Dallas (DFW) have the shortest average one-way travel time for 1-stop routes: 7h 14m.
Which airport typically offers the quickest layover for flights from Louisville to San Diego?
Average layover duration for 1-stop one-way flights from Louisville to San Diego, chosen by Cheapflights users in the last 12 months, grouped by stopover airport.
Flights via Chicago (ORD) offer the fastest connection on this route, with an average layover time of 1h 48m.
Reviews of airlines servicing San Diego
Get insights into the airlines that provide service to San Diego. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Diego. Reviews last updated September 14, 2026.
Get a feel of what it's like to fly with Southwest,Delta, andUnited Airlines from Louisville to San Diego by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
7.5
Comfort
8.0
Boarding
8.1
Overall
8.0
Food
7.0
Crew
8.6
Reviews
1 / 20
10.0
ExcellentWalter,May 2026
LAS - BUR
Entertainment
7.5
Comfort
8.0
Boarding
8.1
Overall
8.0
Food
7.0
Crew
8.6
Reviews
1 / 20
10.0
ExcellentWalter,May 2026
LAS - BUR
Entertainment
7.5
Comfort
8.0
Boarding
8.1
Overall
8.0
Food
7.0
Crew
8.6
Reviews
1 / 20
10.0
ExcellentWalter,May 2026
LAS - BUR
Entertainment
7.5
Comfort
8.0
Boarding
8.1
Overall
8.0
Food
7.0
Crew
8.6
Reviews
1 / 20
10.0
ExcellentWalter,May 2026
LAS - BUR
Entertainment
7.5
Comfort
8.0
Boarding
8.1
Overall
8.0
Food
7.0
Crew
8.6
Reviews
1 / 20
10.0
ExcellentWalter,May 2026
LAS - BUR
Related info for your journey
Find useful and relevant information for your journey from Louisville to San Diego. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near San Diego?
Book flights to San Diego if you plan to visit one of these locationsEl Cajon
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Top 4 airlines flying from Louisville to San Diego
Discover the top 4 airlines that operate flights from Louisville to San Diego. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 14, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$276 | Average$438 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$292 | Average$456 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$299 | Average$433 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$333 | Average$476 | FlexibilityNo cancel fee | On-time63% |