$164+ Cheap flights from Louisville to San Diego (SDF - SAN)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/6. Fares are subject to change and may not be available on all flights or dates of travel.
SDF — SAN
May 23 — May 301
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from Louisville to San Diego with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Louisville to San Diego
Cheapest
Best
Last-minute
One-way
Cheapest flights from Louisville to San DiegoExplore the most affordable flight options available from Louisville to San Diego. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 23, 2026.
Explore the most affordable flight options available from Louisville to San Diego. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 23, 2026.
This United Airlines deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/195:36 am
SDF
- SAN
1 stop7h 06m
United Airlines
Tue 6/21:53 pm
SAN
- SDF
1 stop7h 06m
United Airlines
Deal found 4/22![United Airlines logo]()
$273
This Delta deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/87:20 am
SDF
- SAN
1 stop9h 48m
Delta
Tue 9/1512:50 pm
SAN
- SDF
1 stop8h 09m
Delta
Deal found 4/20![Delta logo]()
$277
This Southwest deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/194:40 pm
SDF
- SAN
1 stop7h 40m
Southwest
Tue 6/29:35 pm
SAN
- SDF
2 stops9h 15m
Southwest
Deal found 4/22![Southwest logo]()
$278
This American Airlines deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/187:55 pm
SDF
- SAN
1 stop7h 01m
American Airlines
Wed 5/2012:17 pm
SAN
- SDF
1 stop7h 56m
American Airlines
Deal found 4/22![American Airlines logo]()
$300
This Delta deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/185:52 pm
SDF
- SAN
1 stop7h 08m
Delta
Tue 5/2610:25 pm
SAN
- SDF
1 stop9h 00m
Delta
Deal found 4/22![Delta logo]()
$302
This American Airlines deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/66:11 pm
SDF
- SAN
1 stop8h 48m
American Airlines
Tue 6/99:54 am
SAN
- SDF
1 stop6h 06m
American Airlines
Deal found 4/20![American Airlines logo]()
$314
This United Airlines deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/122:00 pm
SDF
- SAN
1 stop7h 41m
United Airlines
Tue 5/1910:40 pm
SAN
- SDF
1 stop7h 45m
United Airlines
Deal found 4/22![United Airlines logo]()
$319
This Kiwi.com deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/146:55 pm
SDF
- SAN
1 stop19h 53m
Breeze Airways
Tue 5/1912:54 pm
SAN
- SDF
1 stop16h 42m
Breeze Airways
Deal found 4/19![Breeze Airways logo]()
$325
This Delta deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/303:29 pm
SDF
- SAN
1 stop6h 54m
Delta
Thu 6/41:50 pm
SAN
- SDF
1 stop7h 35m
Delta
Deal found 4/21![Delta logo]()
$327
This American Airlines deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/37:30 pm
SDF
- SAN
1 stop7h 20m
American Airlines
Thu 9/1011:09 am
SAN
- SDF
1 stop8h 57m
American Airlines
Deal found 4/22![American Airlines logo]()
$341
This Southwest deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/305:45 pm
SDF
- SAN
1 stop8h 40m
Southwest
Thu 6/410:30 am
SAN
- SDF
2 stops10h 55m
Southwest
Deal found 4/22![Southwest logo]()
$346
Best flights from Louisville to San DiegoDiscover carefully curated flight deals from Louisville to San Diego that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 23, 2026.
Discover carefully curated flight deals from Louisville to San Diego that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 23, 2026.
This United Airlines deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/205:36 am
SDF
- SAN
1 stop7h 06m
United Airlines
Wed 6/311:58 am
SAN
- SDF
1 stop7h 17m
United Airlines
Deal found 4/22![United Airlines logo]()
$273
This Delta deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/106:49 am
SDF
- SAN
1 stop6h 54m
Delta
Mon 7/610:17 pm
SAN
- SDF
1 stop8h 37m
Delta
Deal found 4/21![Delta logo]()
$367
This Southwest deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/1910:30 am
SDF
- SAN
1 stop11h 50m
Southwest
Tue 5/269:15 am
SAN
- SDF
2 stops8h 50m
Southwest
Deal found 4/19![Southwest logo]()
$376
This United Airlines deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/135:36 am
SDF
- SAN
1 stop7h 06m
United Airlines
Sat 5/1610:40 pm
SAN
- SDF
1 stop7h 45m
United Airlines
Deal found 4/22![United Airlines logo]()
$400
This Delta deal was found by Cheapflights users on 4/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/410:39 am
SDF
- SAN
1 stop6h 41m
Delta
Wed 6/1011:53 am
SAN
- SDF
1 stop9h 01m
Delta
Deal found 4/18![Delta logo]()
$439
This Southwest deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/56:05 pm
SDF
- SAN
2 stops8h 00m
Southwest
Sun 6/710:40 pm
SAN
- SDF
1 stop8h 25m
Southwest
Deal found 4/20![Southwest logo]()
$442
This Southwest deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/247:45 pm
SDF
- SAN
1 stop6h 35m
Southwest
Tue 6/3010:55 am
SAN
- SDF
2 stops7h 45m
Southwest
Deal found 4/22![Southwest logo]()
$444
This Delta deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/171:02 pm
SDF
- SAN
1 stop6h 54m
Delta
Sun 6/2110:17 pm
SAN
- SDF
1 stop8h 38m
Delta
Deal found 4/20![Delta logo]()
$460
This Southwest deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/36:05 pm
SDF
- SAN
2 stops8h 00m
Southwest
Mon 7/610:40 pm
SAN
- SDF
1 stop8h 25m
Southwest
Deal found 4/23![Southwest logo]()
$444
This Southwest deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/305:25 pm
SDF
- SAN
2 stops7h 30m
Southwest
Sun 7/59:40 pm
SAN
- SDF
1 stop11h 50m
Southwest
Deal found 4/19![Southwest logo]()
$460
Last-minute flights from Louisville to San DiegoDiscover last-minute flight deals from Louisville to San Diego. Data last updated April 23, 2026 and is based on user searches.
Discover last-minute flight deals from Louisville to San Diego. Data last updated April 23, 2026 and is based on user searches.
This United Airlines deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/122:00 pm
SDF
- SAN
1 stop7h 41m
United Airlines
Tue 5/1910:40 pm
SAN
- SDF
1 stop7h 45m
United Airlines
Deal found 4/22![United Airlines logo]()
$319
This Kiwi.com deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/146:55 pm
SDF
- SAN
1 stop19h 53m
Breeze Airways
Tue 5/1912:54 pm
SAN
- SDF
1 stop16h 42m
Breeze Airways
Deal found 4/19![Breeze Airways logo]()
$325
This American Airlines deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/155:41 pm
SDF
- SAN
1 stop7h 19m
American Airlines
Mon 5/181:18 pm
SAN
- SDF
1 stop8h 05m
American Airlines
Deal found 4/21![American Airlines logo]()
$355
This American Airlines deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/187:55 pm
SDF
- SAN
1 stop7h 01m
American Airlines
Wed 5/2012:17 pm
SAN
- SDF
1 stop7h 56m
American Airlines
Deal found 4/22![American Airlines logo]()
$300
This Delta deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/185:52 pm
SDF
- SAN
1 stop7h 08m
Delta
Tue 5/2610:25 pm
SAN
- SDF
1 stop9h 00m
Delta
Deal found 4/22![Delta logo]()
$302
This United Airlines deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/195:36 am
SDF
- SAN
1 stop7h 06m
United Airlines
Tue 6/21:53 pm
SAN
- SDF
1 stop7h 06m
United Airlines
Deal found 4/22![United Airlines logo]()
$273
This Southwest deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/194:40 pm
SDF
- SAN
1 stop7h 40m
Southwest
Tue 6/29:35 pm
SAN
- SDF
2 stops9h 15m
Southwest
Deal found 4/22![Southwest logo]()
$278
This American Airlines deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/246:56 pm
SDF
- SAN
1 stop7h 43m
American Airlines
Wed 5/277:28 am
SAN
- SDF
1 stop7h 58m
American Airlines
Deal found 4/21![American Airlines logo]()
$347
This Delta deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/303:29 pm
SDF
- SAN
1 stop6h 54m
Delta
Thu 6/41:50 pm
SAN
- SDF
1 stop7h 35m
Delta
Deal found 4/21![Delta logo]()
$327
This Southwest deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/305:45 pm
SDF
- SAN
1 stop8h 40m
Southwest
Thu 6/410:30 am
SAN
- SDF
2 stops10h 55m
Southwest
Deal found 4/22![Southwest logo]()
$346
One-way flights from Louisville to San DiegoSearch for one-way flight options from Louisville to San Diego. Find affordable one-way fares based on user searches. Data last updated April 23, 2026.
Search for one-way flight options from Louisville to San Diego. Find affordable one-way fares based on user searches. Data last updated April 23, 2026.
This American Airlines deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/167:01 pm
SDF
- SAN
1 stop7h 32m
American Airlines
Deal found 4/22![American Airlines logo]()
$164
This Kiwi.com deal was found by Cheapflights users on 4/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/308:06 pm
SDF
- SAN
1 stop18h 18m
Breeze Airways
Deal found 4/18![Breeze Airways logo]()
$184
This Kiwi.com deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/1510:33 am
SDF
- SAN
3 stops37h 31m
Multiple Airlines
Deal found 4/21![Multiple Airlines logo]()
$186
This Kiwi.com deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/68:06 pm
SDF
- SAN
1 stop18h 18m
Breeze Airways
Deal found 4/20![Breeze Airways logo]()
$192
This Kiwi.com deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/68:06 pm
SDF
- SAN
3 stops39h 36m
Multiple Airlines
Deal found 4/21![Multiple Airlines logo]()
$211
This Kiwi.com deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/710:33 am
SDF
- SAN
3 stops40h 17m
Multiple Airlines
Deal found 4/22![Multiple Airlines logo]()
$222
This Kiwi.com deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/76:55 pm
SDF
- SAN
1 stop19h 53m
Breeze Airways
Deal found 4/22![Breeze Airways logo]()
$228
This United Airlines deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/115:20 am
SDF
- SAN
1 stop7h 08m
United Airlines
Deal found 4/22![United Airlines logo]()
$229
This Kiwi.com deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/68:06 pm
SDF
- SAN
3 stops39h 36m
Multiple Airlines
Deal found 4/20![Multiple Airlines logo]()
$230
This United Airlines deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/62:05 pm
SDF
- SAN
2 stops12h 49m
United Airlines
Deal found 4/21![United Airlines logo]()
$233
Find flight deals from Louisville to San Diego
Discover tips and strategies to find the most affordable flight options for your journey from Louisville (SDF) to San Diego (SAN). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated April 23, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $273 (United Airlines) |
One-way from | $164 (American Airlines) |
Popular in | March |
Cheapest in | August |
Average price | $538 |
Cheapflights Fare Finder
Customize your flight search to find flights from Louisville to San Diego that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 23, 2026.
Use the filters below to find and compare flights from Louisville to San Diego that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
LouisvilleSan Diego
SDF - SAN
SDFSAN
Louisville Intl
Wed 5/20
5:36 am-9:42 am
1 stop7h 06m
San Diego
Wed 6/3
11:58 am-10:15 pm
1 stop7h 17m
$273
LouisvilleSan Diego
SDF - SAN
SDFSAN
Louisville Intl
Wed 6/10
6:49 am-10:43 am
1 stop6h 54m
San Diego
Mon 7/6
10:17 pm-9:54 am
1 stop8h 37m
$367
LouisvilleSan Diego
SDF - SAN
SDFSAN
Louisville Intl
Tue 5/19
10:30 am-7:20 pm
1 stop11h 50m
San Diego
Tue 5/26
9:15 am-9:05 pm
2 stops8h 50m
$376
LouisvilleSan Diego
SDF - SAN
SDFSAN
Louisville Intl
Wed 5/13
5:36 am-9:42 am
1 stop7h 06m
San Diego
Sat 5/16
10:40 pm-9:25 am
1 stop7h 45m
$400
LouisvilleSan Diego
SDF - SAN
SDFSAN
Louisville Intl
Thu 6/4
10:39 am-2:20 pm
1 stop6h 41m
San Diego
Wed 6/10
11:53 am-11:54 pm
1 stop9h 01m
$439
LouisvilleSan Diego
SDF - SAN
SDFSAN
Louisville Intl
Fri 6/5
6:05 pm-11:05 pm
2 stops8h 00m
San Diego
Sun 6/7
10:40 pm-10:05 am
1 stop8h 25m
$442
Quickest round-trip
LouisvilleSan Diego
SDF - SAN
SDFSAN
Louisville Intl
Wed 6/24
7:45 pm-11:20 pm
1 stop6h 35m
San Diego
Tue 6/30
10:55 am-9:40 pm
2 stops7h 45m
$444
LouisvilleSan Diego
SDF - SAN
SDFSAN
Louisville Intl
Fri 7/3
6:05 pm-11:05 pm
2 stops8h 00m
San Diego
Mon 7/6
10:40 pm-10:05 am
1 stop8h 25m
$444
LouisvilleSan Diego
SDF - SAN
SDFSAN
Louisville Intl
Wed 6/17
1:02 pm-4:56 pm
1 stop6h 54m
San Diego
Sun 6/21
10:17 pm-9:55 am
1 stop8h 38m
$460
LouisvilleSan Diego
SDF - SAN
SDFSAN
Louisville Intl
Tue 6/30
5:25 pm-9:55 pm
2 stops7h 30m
San Diego
Sun 7/5
9:40 pm-12:30 pm
1 stop11h 50m
$460
Showing 1-10 of 22 resultsSorted by cheapest first
Compare providers for flights from Louisville to San Diego
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Louisville to San Diego in April.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Louisville-San Diego flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Louisville-San Diego flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Louisville-San Diego flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Louisville-San Diego flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Louisville-San Diego flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Louisville to San Diego
Have a flexible travel schedule? Discover the best time to fly to San Diego from Louisville with our price prediction graph.
SDF-SAN
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Louisville to San Diego
How far ahead should I book a flight from Louisville to San Diego?
Booking 5 days in advance of your planned departure date is, on average, the best time to get cheap flights from Louisville to San Diego. The general trend is that the closer you book to the departure date, the more expensive your flight will be.
What is the cheapest month to book a flight from Louisville to San Diego?
Currently, August is the cheapest month in which you can book a flight from Louisville to San Diego (average of $346). Flying from Louisville to San Diego in March is currently the most expensive (average of $567). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Louisville to San Diego?
Reviews of airlines servicing San Diego
Get insights into the airlines that provide service to San Diego. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Diego. Reviews last updated April 23, 2026.
Get a feel of what it's like to fly with Southwest,Delta, andUnited Airlines from Louisville to San Diego by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Food
7.0
Crew
8.6
Entertainment
7.5
Comfort
8.0
Overall
8.0
Boarding
8.1
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Food
7.0
Crew
8.6
Entertainment
7.5
Comfort
8.0
Overall
8.0
Boarding
8.1
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Food
7.0
Crew
8.6
Entertainment
7.5
Comfort
8.0
Overall
8.0
Boarding
8.1
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Food
7.0
Crew
8.6
Entertainment
7.5
Comfort
8.0
Overall
8.0
Boarding
8.1
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Food
7.0
Crew
8.6
Entertainment
7.5
Comfort
8.0
Overall
8.0
Boarding
8.1
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Food
7.0
Crew
8.6
Entertainment
7.5
Comfort
8.0
Overall
8.0
Boarding
8.1
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Related info for your journey
Find useful and relevant information for your journey from Louisville to San Diego. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near San Diego?
Book flights to San Diego if you plan to visit one of these locationsEl Cajon
Chula Vista
National City
Coronado
La Mesa
Poway
Julian
Lemon Grove
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
Other flight options
Other flights from Louisville
Popular flights
San Diego flight routes
Alternative routes for Louisville to San Diego
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to San Diego by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Louisville to San Diego by cabin class
Find flights from Louisville to San Diego, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Louisville and San Diego flights
Browse other Louisville and San Diego flight options. Last updated on April 23, 2026.
Other flights from Louisville
Browse through other flights departing from Louisville. Flights are based on user searches made on Cheapflights and were last updated on April 23, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Other flights to San Diego
Explore flights to San Diego departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on April 23, 2026.
Top 5 airlines flying from Louisville to San Diego
Discover the top 5 airlines that operate flights from Louisville to San Diego. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 23, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$112 | Average$295 | FlexibilityNo cancel fee | On-time65% | |
| Cheapest$239 | Average$396 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$260 | Average$460 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$282 | Average$422 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$323 | Average$467 | FlexibilityNo cancel fee | On-time63% |