$143+ Cheap flights from Louisville to San Diego (SDF - SAN)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/15. Fares are subject to change and may not be available on all flights or dates of travel.
SDF — SAN
Nov 21 — Nov 281
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from Louisville to San Diego with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Louisville to San Diego
Cheapest
Best
Last-minute
One-way
Cheapest flights from Louisville to San DiegoExplore the most affordable flight options available from Louisville to San Diego. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 22, 2026.
Explore the most affordable flight options available from Louisville to San Diego. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 22, 2026.
This Kiwi.com deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/55:12 pm -
1 stop21h 40m
Thu 12/107:51 pm -
1 stop20h 28m
Deal found 10/20![Multiple Airlines logo]()
$276
This Kiwi.com deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/48:47 am -
1 stop12h 23m
Thu 12/107:51 pm -
1 stop20h 28m
Deal found 10/20![Multiple Airlines logo]()
$279
This Kiwi.com deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/55:12 pm -
1 stop21h 40m
Sun 12/67:51 pm -
1 stop20h 28m
Deal found 10/20![Multiple Airlines logo]()
$280
This Kiwi.com deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/78:47 am -
2 stops26h 15m
Thu 12/107:51 pm -
1 stop20h 28m
Deal found 10/20![Multiple Airlines logo]()
$281
This Kiwi.com deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/48:47 am -
1 stop12h 23m
Sun 12/67:51 pm -
1 stop20h 28m
Deal found 10/20![Multiple Airlines logo]()
$283
This Southwest deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/1010:15 am -
1 stop8h 05m
Tue 11/176:15 am -
1 stop7h 55m
Deal found 10/20![Southwest logo]()
$285
This Kiwi.com deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/55:12 pm -
1 stop21h 40m
Tue 12/81:22 pm -
1 stop24h 10m
Deal found 10/20![Breeze Airways logo]()
$303
This Southwest deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/37:35 pm -
1 stop6h 50m
Thu 12/106:45 am -
1 stop9h 10m
Deal found 10/19![Southwest logo]()
$304
This Kiwi.com deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/48:47 am -
1 stop12h 23m
Tue 12/81:22 pm -
1 stop24h 10m
Deal found 10/20![Multiple Airlines logo]()
$306
This Southwest deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/73:50 pm -
2 stops9h 05m
Thu 12/1012:35 pm -
2 stops7h 20m
Deal found 10/20![Southwest logo]()
$309
This Delta deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/216:29 pm -
1 stop7h 25m
Thu 1/72:00 pm -
1 stop7h 02m
Deal found 10/19![Delta logo]()
$311
Best flights from Louisville to San DiegoDiscover carefully curated flight deals from Louisville to San Diego that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 22, 2026.
Discover carefully curated flight deals from Louisville to San Diego that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 22, 2026.
This Southwest deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/131:05 pm -
2 stops9h 50m
Sun 11/1510:40 pm -
1 stop8h 50m
Deal found 10/20![Southwest logo]()
$290
This Delta deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1910:13 am -
1 stop9h 20m
Thu 11/266:20 am -
1 stop7h 34m
Deal found 10/21![Delta logo]()
$311
This United Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/197:00 am -
1 stop6h 59m
Thu 11/266:45 am -
2 stops10h 48m
Deal found 10/21![United Airlines logo]()
$334
This Southwest deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/187:20 am -
2 stops7h 30m
Wed 11/2510:35 pm -
1 stop10h 10m
Deal found 10/19![Southwest logo]()
$323
This Delta deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/215:59 pm -
1 stop7h 25m
Thu 11/268:00 am -
1 stop8h 14m
Deal found 10/20![Delta logo]()
$355
This Delta deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/116:50 am -
1 stop9h 12m
Thu 12/179:50 pm -
1 stop8h 18m
Deal found 10/20![Delta logo]()
$355
This United Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/232:10 pm -
1 stop7h 24m
Wed 12/26:20 am -
2 stops11h 40m
Deal found 10/21![United Airlines logo]()
$436
This Southwest deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/55:35 pm -
2 stops8h 25m
Mon 11/910:35 pm -
1 stop9h 50m
Deal found 10/21![Southwest logo]()
$461
This Delta deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/226:42 am -
1 stop7h 13m
Mon 11/309:50 pm -
1 stop8h 18m
Deal found 10/21![Delta logo]()
$460
This Southwest deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/257:20 am -
1 stop6h 15m
Mon 1/43:00 pm -
1 stop5h 45m
Deal found 10/18![Southwest logo]()
$487
This Delta deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/187:50 am -
1 stop9h 39m
Fri 11/206:30 am -
2 stops13h 16m
Deal found 10/20![Delta logo]()
$473
This Delta deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/275:45 pm -
1 stop8h 18m
Thu 4/16:15 am -
1 stop7h 36m
Deal found 10/17![Delta logo]()
$487
Last-minute flights from Louisville to San DiegoDiscover last-minute flight deals from Louisville to San Diego. Data last updated October 22, 2026 and is based on user searches.
Discover last-minute flight deals from Louisville to San Diego. Data last updated October 22, 2026 and is based on user searches.
This Southwest deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/1010:15 am -
1 stop8h 05m
Tue 11/176:15 am -
1 stop7h 55m
Deal found 10/20![Southwest logo]()
$285
This Kiwi.com deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/138:47 am -
1 stop12h 51m
Tue 11/171:22 pm -
1 stop23h 04m
Deal found 10/20![Multiple Airlines logo]()
$346
This Delta deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/163:00 pm -
1 stop7h 41m
Thu 11/2610:30 pm -
1 stop9h 02m
Deal found 10/20![Delta logo]()
$329
This Southwest deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/167:35 pm -
1 stop6h 50m
Mon 11/2310:40 pm -
1 stop8h 20m
Deal found 10/19![Southwest logo]()
$330
This Kiwi.com deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/168:47 am -
1 stop12h 51m
Tue 11/171:22 pm -
1 stop23h 04m
Deal found 10/20![Multiple Airlines logo]()
$344
This American Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/176:16 pm -
1 stop8h 38m
Tue 11/2410:45 pm -
1 stop7h 43m
Deal found 10/21![American Airlines logo]()
$316
This Southwest deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/185:40 am -
1 stop8h 10m
Wed 11/2510:35 pm -
1 stop10h 10m
Deal found 10/19![Southwest logo]()
$318
This Delta deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/197:05 am -
1 stop7h 33m
Wed 11/256:20 am -
1 stop7h 34m
Deal found 10/20![Delta logo]()
$311
This United Airlines deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/195:10 am -
1 stop7h 17m
Mon 11/236:45 am -
2 stops8h 47m
Deal found 10/20![United Airlines logo]()
$334
One-way flights from Louisville to San DiegoSearch for one-way flight options from Louisville to San Diego. Find affordable one-way fares based on user searches. Data last updated October 22, 2026.
Search for one-way flight options from Louisville to San Diego. Find affordable one-way fares based on user searches. Data last updated October 22, 2026.
This Southwest deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/1512:10 pm -
1 stop7h 10m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/20![Southwest logo]()
$143
This American Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/61:11 pm -
1 stop9h 25m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/21![American Airlines logo]()
$156
This United Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/129:00 am -
2 stops12h 28m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/21![United Airlines logo]()
$161
This Kiwi.com deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/168:47 am -
1 stop12h 51m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/18![Multiple Airlines logo]()
$164
This Delta deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/154:00 pm -
1 stop7h 25m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/21![Delta logo]()
$182
This Delta deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/2412:14 pm -
1 stop9h 30m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/20![Delta logo]()
$200
This Southwest deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/153:50 pm -
2 stops8h 10m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/20![Southwest logo]()
$205
This Southwest deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/1912:40 pm -
2 stops9h 05m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/18![Southwest logo]()
$213
This Kiwi.com deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/74:06 pm -
1 stop22h 46m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/20![Breeze Airways logo]()
$217
Find flight deals from Louisville to San Diego
Discover tips and strategies to find the most affordable flight options for your journey from Louisville (SDF) to San Diego (SAN). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 22, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $276 (Kiwi.com) |
One-way from | $143 (Southwest) |
Popular in | March |
Cheapest in | February |
Average price | $470 |
Cheapflights Fare Finder
Customize your flight search to find flights from Louisville to San Diego that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 22, 2026.
Use the filters below to find and compare flights from Louisville to San Diego that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
LouisvilleSan Diego
SDF Louisville Intl - SAN San Diego
SDFSAN
Louisville Intl
Fri 2/19
7:55 pm-12:10 am
1 stop7h 15m
San Diego
Wed 12/31
12:00 am-3:00 am
Nonstop0h 00m
$143
Quickest round-trip
LouisvilleSan Diego
SDF Louisville Intl - SAN San Diego
SDFSAN
Louisville Intl
Tue 1/12
6:20 pm-10:10 pm
1 stop6h 50m
San Diego
Wed 12/31
12:00 am-3:00 am
Nonstop0h 00m
$143
LouisvilleSan Diego
SDF Louisville Intl - SAN San Diego
SDFSAN
Louisville Intl
Wed 1/13
10:15 am-2:12 pm
1 stop6h 57m
San Diego
Wed 12/31
12:00 am-3:00 am
Nonstop0h 00m
$156
LouisvilleSan Diego
SDF Louisville Intl - SAN San Diego
SDFSAN
Louisville Intl
Thu 12/17
6:50 am-11:20 am
1 stop7h 30m
San Diego
Wed 12/31
12:00 am-3:00 am
Nonstop0h 00m
$156
LouisvilleSan Diego
SDF Louisville Intl - SAN San Diego
SDFSAN
Louisville Intl
Tue 1/12
9:00 am-6:28 pm
2 stops12h 28m
San Diego
Wed 12/31
12:00 am-3:00 am
Nonstop0h 00m
$161
LouisvilleSan Diego
SDF Louisville Intl - SAN San Diego
SDFSAN
Louisville Intl
Mon 11/16
8:47 am-11:57 pm
2 stops42h 10m
San Diego
Wed 12/31
12:00 am-3:00 am
Nonstop0h 00m
$221
LouisvilleSan Diego
SDF Louisville Intl - SAN San Diego
SDFSAN
Louisville Intl
Sat 3/27
5:45 pm-11:03 pm
1 stop8h 18m
San Diego
Wed 12/31
12:00 am-3:00 am
Nonstop0h 00m
$244
LouisvilleSan Diego
SDF Louisville Intl - SAN San Diego
SDFSAN
Louisville Intl
Wed 1/6
9:04 am-3:34 pm
2 stops9h 30m
San Diego
Wed 12/31
12:00 am-3:00 am
Nonstop0h 00m
$249
LouisvilleSan Diego
SDF Louisville Intl - SAN San Diego
SDFSAN
Louisville Intl
Sat 3/27
9:00 am-5:27 pm
2 stops11h 27m
San Diego
Wed 12/31
12:00 am-3:00 am
Nonstop0h 00m
$249
LouisvilleSan Diego
SDF Louisville Intl - SAN San Diego
SDFSAN
Louisville Intl
Fri 11/13
1:05 pm-7:55 pm
2 stops9h 50m
San Diego
Sun 11/15
10:40 pm-10:30 am
1 stop8h 50m
$290
Showing 1-10 of 21 resultsSorted by cheapest first
Compare providers for flights from Louisville to San Diego
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Louisville to San Diego in October.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy- | Trust Score*1 star |
- Most accurate provider: When it comes to deals on Louisville-San Diego flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Louisville-San Diego flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Louisville-San Diego flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Louisville-San Diego flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Louisville-San Diego flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Louisville to San Diego
Have a flexible travel schedule? Discover the best time to fly to San Diego from Louisville with our price prediction graph.
SDF-SAN
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Louisville to San Diego
Prices
More
How far ahead should I book a flight from Louisville to San Diego?
Booking 9 days in advance of your planned departure date is, on average, the best time to get cheap flights from Louisville to San Diego. The general trend is that the closer you book to the departure date, the more expensive your flight will be.
What is the cheapest month to book a flight from Louisville to San Diego?
Currently, February is the cheapest month in which you can book a flight from Louisville to San Diego (average of $378). Flying from Louisville to San Diego in March is currently the most expensive (average of $544). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Louisville to San Diego?
Airfare is below average for this route at the moment.
Louisville to San Diego flights typically cost between $348 and $515 in December.The cheapest round-trip price found within the last 5 days was $276 on Multiple Airlines (Dec 5-Dec 10).
What’s the top layover airport for flights from Louisville to San Diego?
Share of 1-stop round-trip flights from Louisville to San Diego chosen by Cheapflights users in the past 12 months, using the same layover each way.
Chicago (ORD) – chosen by Cheapflights users on 50% of 1-stop itineraries from Louisville to San Diego on Cheapflights.
What’s the cheapest layover airport for flights from Louisville to San Diego?
Average round-trip fare for 1-stop flights from Louisville to San Diego, chosen by Cheapflights users in the past 12 months, with the same layover each way.
Dallas (DFW) is the most affordable 1-stop option, with an average round-trip price of $396.
What’s the fastest layover option from Louisville to San Diego?
Shortest average travel time for 1-stop one-way flights from Louisville to San Diego, based on itineraries clicked by Cheapflights users over the past 12 months, grouped by layover airport.
Flights via Dallas (DFW) have the shortest average one-way travel time for 1-stop routes: 7h 14m.
Which airport typically offers the quickest layover for flights from Louisville to San Diego?
Average layover duration for 1-stop one-way flights from Louisville to San Diego, chosen by Cheapflights users in the last 12 months, grouped by stopover airport.
Flights via Chicago (ORD) offer the fastest connection on this route, with an average layover time of 1h 48m.
Reviews of airlines servicing San Diego
Get insights into the airlines that provide service to San Diego. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Diego. Reviews last updated October 22, 2026.
Get a feel of what it's like to fly with Southwest,Delta, andUnited Airlines from Louisville to San Diego by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Boarding
8.1
Overall
7.9
Crew
8.6
Entertainment
7.4
Food
7.0
Comfort
8.0
Reviews
1 / 20
10.0
ExcellentWalter,May 2026
LAS - BUR
Boarding
8.1
Overall
7.9
Crew
8.6
Entertainment
7.4
Food
7.0
Comfort
8.0
Reviews
1 / 20
10.0
ExcellentWalter,May 2026
LAS - BUR
Boarding
8.1
Overall
7.9
Crew
8.6
Entertainment
7.4
Food
7.0
Comfort
8.0
Reviews
1 / 20
10.0
ExcellentWalter,May 2026
LAS - BUR
Boarding
8.1
Overall
7.9
Crew
8.6
Entertainment
7.4
Food
7.0
Comfort
8.0
Reviews
1 / 20
10.0
ExcellentWalter,May 2026
LAS - BUR
Boarding
8.1
Overall
7.9
Crew
8.6
Entertainment
7.4
Food
7.0
Comfort
8.0
Reviews
1 / 20
10.0
ExcellentWalter,May 2026
LAS - BUR
Related info for your journey
Find useful and relevant information for your journey from Louisville to San Diego. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near San Diego?
Book flights to San Diego if you plan to visit one of these locationsEl Cajon
National City
Chula Vista
San Ysidro
Poway
Coronado
La Mesa
Julian
Santee
Lemon Grove
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
Other flight options
Other flights from Louisville
Popular flights
San Diego flight routes
Alternative routes for Louisville to San Diego
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to San Diego by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Louisville to San Diego by cabin class
Find flights from Louisville to San Diego, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Louisville and San Diego flights
Browse other Louisville and San Diego flight options. Last updated on October 22, 2026.
Other flights from Louisville
Browse through other flights departing from Louisville. Flights are based on user searches made on Cheapflights and were last updated on October 22, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Other flights to San Diego
Explore flights to San Diego departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on October 22, 2026.
Top 4 airlines flying from Louisville to San Diego
Discover the top 4 airlines that operate flights from Louisville to San Diego. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 22, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$278 | Average$448 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$299 | Average$399 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$333 | Average$454 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$333 | Average$478 | FlexibilityNo cancel fee | On-time63% |