$165+ Cheap flights from Louisville to San Diego (SDF - SAN)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/15. Fares are subject to change and may not be available on all flights or dates of travel.
SDF — SAN
Jun 5 — Jun 121
Round-trip
1 adult, Economy
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Find cheap flights from Louisville to San Diego with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Louisville to San Diego
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Cheapest flights from Louisville to San DiegoExplore the most affordable flight options available from Louisville to San Diego. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 6, 2026.
Explore the most affordable flight options available from Louisville to San Diego. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 6, 2026.
This Delta deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/83:24 pm
SDF
- SAN
1 stop7h 34m
Delta
Tue 9/156:20 am
SAN
- SDF
1 stop7h 32m
Delta
Deal found 5/1![Delta logo]()
$321
This American Airlines deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/307:45 pm
SDF
- SAN
1 stop7h 14m
American Airlines
Wed 6/101:23 pm
SAN
- SDF
1 stop8h 05m
American Airlines
Deal found 5/3![American Airlines logo]()
$327
This American Airlines deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/177:18 pm
SDF
- SAN
1 stop7h 30m
American Airlines
Tue 6/237:15 am
SAN
- SDF
1 stop8h 45m
American Airlines
Deal found 5/4![American Airlines logo]()
$328
This American Airlines deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/87:08 pm
SDF
- SAN
1 stop7h 26m
American Airlines
Tue 9/151:45 pm
SAN
- SDF
1 stop6h 21m
American Airlines
Deal found 5/5![American Airlines logo]()
$329
This Southwest deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/285:25 pm
SDF
- SAN
1 stop8h 40m
Southwest
Wed 6/37:25 am
SAN
- SDF
1 stop8h 10m
Southwest
Deal found 5/5![Southwest logo]()
$331
This American Airlines deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/17:45 pm
SDF
- SAN
1 stop7h 14m
American Airlines
Mon 6/810:45 pm
SAN
- SDF
1 stop8h 50m
American Airlines
Deal found 5/5![American Airlines logo]()
$333
This Southwest deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/305:45 pm
SDF
- SAN
1 stop8h 40m
Southwest
Sat 6/69:40 pm
SAN
- SDF
2 stops9h 35m
Southwest
Deal found 5/4![Southwest logo]()
$338
This American Airlines deal was found by Cheapflights users on 5/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/17:45 pm
SDF
- SAN
1 stop7h 14m
American Airlines
Tue 6/3010:45 pm
SAN
- SDF
1 stop8h 50m
American Airlines
Deal found 5/2![American Airlines logo]()
$362
This Delta deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/247:50 am
SDF
- SAN
1 stop9h 30m
Delta
Wed 5/276:15 am
SAN
- SDF
1 stop7h 46m
Delta
Deal found 5/4![Delta logo]()
$371
Best flights from Louisville to San DiegoDiscover carefully curated flight deals from Louisville to San Diego that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 6, 2026.
Discover carefully curated flight deals from Louisville to San Diego that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 6, 2026.
This Delta deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/83:24 pm
SDF
- SAN
1 stop7h 34m
Delta
Tue 9/156:20 am
SAN
- SDF
1 stop7h 32m
Delta
Deal found 5/1![Delta logo]()
$321
This Southwest deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/305:30 am
SDF
- SAN
1 stop9h 00m
Southwest
Sat 10/37:15 am
SAN
- SDF
2 stops9h 35m
Southwest
Deal found 5/6![Southwest logo]()
$381
This United Airlines deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/165:35 am
SDF
- SAN
1 stop8h 40m
United Airlines
Sat 9/1912:01 pm
SAN
- SDF
1 stop7h 13m
United Airlines
Deal found 5/5![United Airlines logo]()
$393
This Delta deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/211:17 pm
SDF
- SAN
1 stop9h 05m
Delta
Tue 8/2510:30 pm
SAN
- SDF
1 stop9h 02m
Delta
Deal found 5/4![Delta logo]()
$389
This Southwest deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/1610:50 am
SDF
- SAN
2 stops10h 30m
Southwest
Sat 9/196:20 am
SAN
- SDF
2 stops7h 55m
Southwest
Deal found 5/5![Southwest logo]()
$403
This United Airlines deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/189:30 am
SDF
- SAN
1 stop6h 47m
United Airlines
Wed 8/199:45 pm
SAN
- SDF
1 stop9h 29m
United Airlines
Deal found 5/1![United Airlines logo]()
$421
This United Airlines deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/87:10 am
SDF
- SAN
1 stop9h 07m
United Airlines
Tue 9/157:15 am
SAN
- SDF
2 stops12h 36m
United Airlines
Deal found 5/1![United Airlines logo]()
$426
Last-minute flights from Louisville to San DiegoDiscover last-minute flight deals from Louisville to San Diego. Data last updated May 6, 2026 and is based on user searches.
Discover last-minute flight deals from Louisville to San Diego. Data last updated May 6, 2026 and is based on user searches.
This Delta deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/247:50 am
SDF
- SAN
1 stop9h 30m
Delta
Wed 5/276:15 am
SAN
- SDF
1 stop7h 46m
Delta
Deal found 5/4![Delta logo]()
$371
This American Airlines deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/246:59 am
SDF
- SAN
1 stop8h 27m
American Airlines
Wed 5/277:15 am
SAN
- SDF
1 stop8h 45m
American Airlines
Deal found 5/5![American Airlines logo]()
$375
This Southwest deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/285:25 pm
SDF
- SAN
1 stop8h 40m
Southwest
Wed 6/37:25 am
SAN
- SDF
1 stop8h 10m
Southwest
Deal found 5/5![Southwest logo]()
$331
This American Airlines deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/307:45 pm
SDF
- SAN
1 stop7h 14m
American Airlines
Wed 6/101:23 pm
SAN
- SDF
1 stop8h 05m
American Airlines
Deal found 5/3![American Airlines logo]()
$327
This Southwest deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/305:45 pm
SDF
- SAN
1 stop8h 40m
Southwest
Sat 6/69:40 pm
SAN
- SDF
2 stops9h 35m
Southwest
Deal found 5/4![Southwest logo]()
$338
This American Airlines deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/17:45 pm
SDF
- SAN
1 stop7h 14m
American Airlines
Mon 6/810:45 pm
SAN
- SDF
1 stop8h 50m
American Airlines
Deal found 5/5![American Airlines logo]()
$333
This American Airlines deal was found by Cheapflights users on 5/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/17:45 pm
SDF
- SAN
1 stop7h 14m
American Airlines
Tue 6/3010:45 pm
SAN
- SDF
1 stop8h 50m
American Airlines
Deal found 5/2![American Airlines logo]()
$362
This American Airlines deal was found by Cheapflights users on 5/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/177:18 pm
SDF
- SAN
1 stop7h 30m
American Airlines
Tue 6/231:55 pm
SAN
- SDF
1 stop6h 24m
American Airlines
Deal found 5/2![American Airlines logo]()
$321
One-way flights from Louisville to San DiegoSearch for one-way flight options from Louisville to San Diego. Find affordable one-way fares based on user searches. Data last updated May 6, 2026.
Search for one-way flight options from Louisville to San Diego. Find affordable one-way fares based on user searches. Data last updated May 6, 2026.
This American Airlines deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/158:55 am
SDF
- SAN
1 stop7h 17m
American Airlines
Deal found 5/5![American Airlines logo]()
$165
This Southwest deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/1510:50 am
SDF
- SAN
2 stops8h 05m
Southwest
Deal found 5/5![Southwest logo]()
$170
This Kiwi.com deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/78:11 pm
SDF
- SAN
1 stop18h 41m
Breeze Airways
Deal found 5/3![Breeze Airways logo]()
$184
This Kiwi.com deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/159:05 pm
SDF
- SAN
3 stops38h 43m
Multiple Airlines
Deal found 5/5![Multiple Airlines logo]()
$200
This United Airlines deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/166:15 am
SDF
- SAN
1 stop7h 36m
United Airlines
Deal found 5/4![United Airlines logo]()
$211
This Kiwi.com deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/138:06 pm
SDF
- SAN
1 stop18h 18m
Breeze Airways
Deal found 5/1![Breeze Airways logo]()
$212
This Kiwi.com deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/146:55 pm
SDF
- SAN
3 stops41h 14m
Multiple Airlines
Deal found 5/3![Multiple Airlines logo]()
$215
This Southwest deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/76:40 am
SDF
- SAN
2 stops8h 40m
Southwest
Deal found 5/3![Southwest logo]()
$216
This Kiwi.com deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/286:55 pm
SDF
- SAN
1 stop19h 53m
Breeze Airways
Deal found 5/5![Breeze Airways logo]()
$217
This Kiwi.com deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/142:27 pm
SDF
- SAN
3 stops54h 32m
Multiple Airlines
Deal found 5/1![Multiple Airlines logo]()
$224
This Delta deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/187:51 pm
SDF
- SAN
1 stop6h 44m
Delta
Deal found 5/4![Delta logo]()
$229
This Southwest deal was found by Cheapflights users on 5/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/98:40 am
SDF
- SAN
2 stops9h 40m
Southwest
Deal found 5/2![Southwest logo]()
$234
Find flight deals from Louisville to San Diego
Discover tips and strategies to find the most affordable flight options for your journey from Louisville (SDF) to San Diego (SAN). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated May 6, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $321 (Delta) |
One-way from | $165 (American Airlines) |
Popular in | March |
Cheapest in | August |
Average price | $427 |
Cheapflights Fare Finder
Customize your flight search to find flights from Louisville to San Diego that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 6, 2026.
Use the filters below to find and compare flights from Louisville to San Diego that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
LouisvilleSan Diego
SDF - SAN
SDFSAN
Louisville Intl
Tue 9/8
3:24 pm-7:58 pm
1 stop7h 34m
San Diego
Tue 9/15
6:20 am-4:52 pm
1 stop7h 32m
$321
LouisvilleSan Diego
SDF - SAN
SDFSAN
Louisville Intl
Wed 9/30
5:30 am-11:30 am
1 stop9h 00m
San Diego
Sat 10/3
7:15 am-7:50 pm
2 stops9h 35m
$381
LouisvilleSan Diego
SDF - SAN
SDFSAN
Louisville Intl
Fri 8/21
1:17 pm-7:22 pm
1 stop9h 05m
San Diego
Tue 8/25
10:30 pm-10:32 am
1 stop9h 02m
$389
LouisvilleSan Diego
SDF - SAN
SDFSAN
Louisville Intl
Wed 9/16
5:35 am-11:15 am
1 stop8h 40m
San Diego
Sat 9/19
12:01 pm-10:14 pm
1 stop7h 13m
$393
LouisvilleSan Diego
SDF - SAN
SDFSAN
Louisville Intl
Wed 9/16
10:50 am-6:20 pm
2 stops10h 30m
San Diego
Sat 9/19
6:20 am-5:15 pm
2 stops7h 55m
$403
LouisvilleSan Diego
SDF - SAN
SDFSAN
Louisville Intl
Tue 8/18
9:30 am-1:17 pm
1 stop6h 47m
San Diego
Wed 8/19
9:45 pm-10:14 am
1 stop9h 29m
$421
LouisvilleSan Diego
SDF - SAN
SDFSAN
Louisville Intl
Tue 9/8
7:10 am-1:17 pm
1 stop9h 07m
San Diego
Tue 9/15
7:15 am-10:51 pm
2 stops12h 36m
$426
Cheapest one-way
LouisvilleSan Diego
SDF - SAN
SDFSAN
Louisville Intl
Tue 9/15
8:55 am-1:12 pm
1 stop7h 17m
$165
LouisvilleSan Diego
SDF - SAN
SDFSAN
Louisville Intl
Tue 9/15
10:50 am-3:55 pm
2 stops8h 05m
$170
LouisvilleSan Diego
SDF - SAN
SDFSAN
Louisville Intl
Wed 10/7
6:40 am-12:20 pm
2 stops8h 40m
$216
Showing 1-10 of 19 resultsSorted by cheapest first
Compare providers for flights from Louisville to San Diego
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Louisville to San Diego in May.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Louisville-San Diego flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Louisville-San Diego flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Louisville-San Diego flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Louisville-San Diego flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Louisville-San Diego flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Louisville to San Diego
Have a flexible travel schedule? Discover the best time to fly to San Diego from Louisville with our price prediction graph.
SDF-SAN
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Louisville to San Diego
How far ahead should I book a flight from Louisville to San Diego?
Booking 5 days in advance of your planned departure date is, on average, the best time to get cheap flights from Louisville to San Diego. The general trend is that the closer you book to the departure date, the more expensive your flight will be.
What is the cheapest month to book a flight from Louisville to San Diego?
Currently, August is the cheapest month in which you can book a flight from Louisville to San Diego (average of $346). Flying from Louisville to San Diego in March is currently the most expensive (average of $567). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Louisville to San Diego?
Reviews of airlines servicing San Diego
Get insights into the airlines that provide service to San Diego. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Diego. Reviews last updated May 6, 2026.
Get a feel of what it's like to fly with Southwest,Delta, andUnited Airlines from Louisville to San Diego by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Boarding
8.1
Entertainment
7.5
Food
7.0
Overall
7.9
Comfort
8.0
Crew
8.6
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Boarding
8.1
Entertainment
7.5
Food
7.0
Overall
7.9
Comfort
8.0
Crew
8.6
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Boarding
8.1
Entertainment
7.5
Food
7.0
Overall
7.9
Comfort
8.0
Crew
8.6
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Boarding
8.1
Entertainment
7.5
Food
7.0
Overall
7.9
Comfort
8.0
Crew
8.6
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Boarding
8.1
Entertainment
7.5
Food
7.0
Overall
7.9
Comfort
8.0
Crew
8.6
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Boarding
8.1
Entertainment
7.5
Food
7.0
Overall
7.9
Comfort
8.0
Crew
8.6
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Related info for your journey
Find useful and relevant information for your journey from Louisville to San Diego. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near San Diego?
Book flights to San Diego if you plan to visit one of these locationsEl Cajon
Chula Vista
National City
Coronado
La Mesa
Poway
Julian
Lemon Grove
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Alternative routes for Louisville to San Diego
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to San Diego by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Louisville to San Diego by cabin class
Find flights from Louisville to San Diego, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Louisville and San Diego flights
Browse other Louisville and San Diego flight options. Last updated on May 6, 2026.
Other flights from Louisville
Browse through other flights departing from Louisville. Flights are based on user searches made on Cheapflights and were last updated on May 6, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Other flights to San Diego
Explore flights to San Diego departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on May 6, 2026.
Top 5 airlines flying from Louisville to San Diego
Discover the top 5 airlines that operate flights from Louisville to San Diego. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 6, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$112 | Average$295 | FlexibilityNo cancel fee | On-time65% | |
| Cheapest$239 | Average$439 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$260 | Average$461 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$282 | Average$424 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$323 | Average$465 | FlexibilityNo cancel fee | On-time63% |