HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
San Diego

$354+ Cheap flights from Islip to San Diego (ISP - SAN)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/29. Fares are subject to change and may not be available on all flights or dates of travel.
ISP — SAN
Oct 15 — Oct 221
Wed 10/15
Wed 10/22
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Islip to San Diego with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Islip to San Diego

Discover tips and strategies to find the most affordable flight options for your journey from Islip (ISP) to San Diego (SAN). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 15, 2025.

Round-trip from

$456
(Kiwi.com)

One-way from

$354
(Southwest)

Popular in

September

Cheapest in

November

Average price

$991
From Islip Long Island to San Diego
Search Deals
One-way flight from Islip Long Island to San Diego
Search Deals
Highest demand for flights based on searches. 22% potential increase in price ($148 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 11% potential price decrease ($55 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in September 2025
Search Deals

Find flight deals from Islip to San Diego

Cheapest flights from Islip to San Diego
Explore the most affordable flight options available from Islip to San Diego. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 15, 2025.

This Kiwi.com deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/287:36 pmISP - SAN
1 stop19h 51mMultiple Airlines
Thu 10/29:03 pmSAN - ISP
2 stops34h 52mMultiple Airlines
Deal found 9/13$435
This Southwest deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/65:35 pmISP - SAN
1 stop7h 55mSouthwest
Mon 10/139:10 pmSAN - ISP
1 stop12h 15mSouthwest
Deal found 9/12$454
This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/3011:25 amISP - SAN
2 stops15h 09mMultiple Airlines
Sat 10/41:12 pmSAN - ISP
1 stop26h 44mMultiple Airlines
Deal found 9/15$456
This Kiwi.com deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/62:25 pmISP - SAN
1 stop25h 11mMultiple Airlines
Mon 10/138:11 amSAN - ISP
2 stops33h 31mMultiple Airlines
Deal found 9/12$517
This Kiwi.com deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/287:36 pmISP - SAN
1 stop19h 51mBreeze Airways
Thu 10/21:21 pmSAN - ISP
1 stop21h 24mBreeze Airways
Deal found 9/13$605
This KAYAK deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/27:36 pmISP - SAN
1 stop19h 51mBreeze Airways
Sun 10/51:21 pmSAN - ISP
1 stop21h 24mBreeze Airways
Deal found 9/15$725
This Cheapflightsfares deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/222:19 pmISP - SAN
1 stop9h 00mMultiple Airlines
Sat 10/46:25 pmSAN - ISP
2 stops13h 33mMultiple Airlines
Deal found 9/14$772
This Cheapflightsfares deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/152:19 pmISP - SAN
1 stop9h 00mMultiple Airlines
Tue 10/216:25 pmSAN - ISP
2 stops13h 39mMultiple Airlines
Deal found 9/14$812
This Cheapflightsfares deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/192:19 pmISP - SAN
1 stop9h 00mMultiple Airlines
Tue 10/146:25 pmSAN - ISP
2 stops13h 39mMultiple Airlines
Deal found 9/14$967

Cheapflights Fare Finder

 
Customize your flight search to find flights from Islip to San Diego that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 15, 2025.
Use the filters below to find and compare flights from Islip to San Diego that are best for you.

Fly from

Islip

Fly to

San Diego

Route

Depart

Return

Price

IslipSan Diego

ISP - SAN

ISPSAN

Islip Long Island

Sun 9/28

7:36 pm-12:27 pm

1 stop19h 51m

San Diego

Thu 10/2

9:03 pm-10:55 am

2 stops34h 52m

$435

IslipSan Diego

ISP - SAN

ISPSAN

Islip Long Island

Mon 10/6

5:35 pm-10:30 pm

1 stop7h 55m

San Diego

Mon 10/13

9:10 pm-12:25 pm

1 stop12h 15m

$454

IslipSan Diego

ISP - SAN

ISPSAN

Islip Long Island

Tue 9/30

11:25 am-11:34 pm

2 stops15h 09m

San Diego

Sat 10/4

1:12 pm-6:56 pm

1 stop26h 44m

$456

IslipSan Diego

ISP - SAN

ISPSAN

Islip Long Island

Mon 10/6

2:25 pm-12:36 pm

1 stop25h 11m

San Diego

Mon 10/13

8:11 am-8:42 pm

2 stops33h 31m

$517

IslipSan Diego

ISP - SAN

ISPSAN

Islip Long Island

Sun 9/28

7:36 pm-12:27 pm

1 stop19h 51m

San Diego

Thu 10/2

1:21 pm-1:45 pm

1 stop21h 24m

$605

IslipSan Diego

ISP - SAN

ISPSAN

Islip Long Island

Thu 10/2

7:36 pm-12:27 pm

1 stop19h 51m

San Diego

Sun 10/5

1:21 pm-1:45 pm

1 stop21h 24m

$725

IslipSan Diego

ISP - SAN

ISPSAN

Islip Long Island

Mon 9/22

2:19 pm-8:19 pm

1 stop9h 00m

San Diego

Sat 10/4

6:25 pm-10:58 am

2 stops13h 33m

$772

IslipSan Diego

ISP - SAN

ISPSAN

Islip Long Island

Fri 9/19

2:19 pm-8:19 pm

1 stop9h 00m

San Diego

Tue 10/14

6:25 pm-11:04 am

2 stops13h 39m

$967

IslipSan Diego

ISP - SAN

ISPSAN

Islip Long Island

Thu 10/2

2:19 pm-8:19 pm

1 stop9h 00m

San Diego

Mon 10/6

6:25 pm-10:58 am

2 stops13h 33m

$1,006

IslipSan Diego

ISP - SAN

ISPSAN

Islip Long Island

Sat 11/29

5:30 am-10:50 am

1 stop8h 20m

$354

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/15

Showing 1-10 of 17 results
1
2

Best time to book a flight from Islip to San Diego

Have a flexible travel schedule? Discover the best time to fly to San Diego from Islip with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Islip to San Diego

What is the cheapest month to book a flight from Islip to San Diego?

Currently, August is the cheapest month in which you can book a flight from Islip to San Diego (average of $286). Flying from Islip to San Diego in March is currently the most expensive (average of $366). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from ISP to SAN?

Find hourly flight availability from Islip to San Diego. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 15, 2025.

A simple way to save on the total cost of your ticket is to fly from Islip to San Diego at noon. If you’re flexible enough to do this you can expect to save up to 58% on your trip compared to booking a flight in the morning.

Reviews of airlines servicing San Diego

Get insights into the airlines that provide service to San Diego. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Diego. Reviews last updated September 15, 2025.
Peruse reviews from past customers who have flown with Southwest from Islip to San Diego to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,242 reviews

Crew

8.6

Boarding

8.1

Entertainment

7.5

Food

7.0

Comfort

8.0

Overall

8.0

Reviews

1 / 20
8.0
Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.
Southwest
8.0
Very good
4,242 reviews
Southwest
8.0
Very good
4,242 reviews

Crew

8.6

Boarding

8.1

Entertainment

7.5

Food

7.0

Comfort

8.0

Overall

8.0

Reviews

1 / 20
8.0
Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.

Related info for your journey

Find useful and relevant information for your journey from Islip to San Diego. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Islip to San Diego?

    Southwest and Breeze Airways can get you from Islip to San Diego in just under 7h 55m. Your travel time can differ by up to 11h 56m. There are 2475 mi between Islip and San Diego. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What is the cheapest airline to fly from Islip to San Diego round-trip?

    Our cheapest airline available from Islip to San Diego is Southwest. Our recent data shows that you can find tickets from as low as $350 on this airline. Users have found that Southwest is 30% cheaper than the other options available to this destination.

  • Can I find deals for flights from Islip to San Diego that include hotel bookings?

    Yes. In addition to deals on Islip to San Diego flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Islip to San Diego?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Islip to San Diego.

  • Can I find deals for business class flights from Islip to San Diego?

    Yes. Cheapflights offers flight deals from Islip to San Diego by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Islip to San Diego?

    Currently, August is the cheapest month in which you can book a flight from Islip to San Diego (average of $286). Flying from Islip to San Diego in March is currently the most expensive (average of $366). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near San Diego?

Book flights to San Diego if you plan to visit one of these locations
El Cajon
Chula Vista
La Mesa
Poway
Lemon Grove
Coronado
Imperial Beach
National City
Alpine

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Islip to San Diego

See prices for flight routes from nearby airports that may be better suited for you.
John F Kennedy Intl to Los Angeles flights
John F Kennedy Intl to Las Vegas flights
Newark to Las Vegas flights
John F Kennedy Intl to San Francisco flights
Newark to Los Angeles flights
Newark to San Francisco flights
LaGuardia to Los Angeles flights
LaGuardia to Las Vegas flights
John F Kennedy Intl to Ontario flights
LaGuardia to San Francisco flights
John F Kennedy Intl to San Diego flights
Newark to San Diego flights
Newark to Burbank flights
Newark to Santa Ana flights
Newark to Ontario flights
LaGuardia to Burbank flights
LaGuardia to Santa Ana flights
John F Kennedy Intl to Santa Ana flights
LaGuardia to San Diego flights
LaGuardia to Ontario flights
John F Kennedy Intl to Palm Springs flights
Newark to Palm Springs flights
Newark to Sacramento flights
Newark to San Jose flights
John F Kennedy Intl to San Jose flights
Buffalo to Las Vegas flights
LaGuardia to Palm Springs flights
Rochester to Las Vegas flights
John F Kennedy Intl to Burbank flights
Newark to Oakland flights
Stewart to Las Vegas flights
Albany to Las Vegas flights
John F Kennedy Intl to Sacramento flights
John F Kennedy Intl to Reno flights
John F Kennedy Intl to Oakland flights
Syracuse to Las Vegas flights
John F Kennedy Intl to Long Beach flights
LaGuardia to San Jose flights
LaGuardia to Sacramento flights
White Plains to Las Vegas flights
Newark to Reno flights
White Plains to Los Angeles flights
LaGuardia to Oakland flights
Rochester to Los Angeles flights
Syracuse to Los Angeles flights
Islip to Las Vegas flights
Stewart to San Francisco flights
LaGuardia to Reno flights
Buffalo to Los Angeles flights
Syracuse to San Francisco flights

Top airline flying from Islip to San Diego

Discover the top airline that operate flights from Islip to San Diego. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 15, 2025.
AirlineCheapestAverageFlexibilityOn-time
SouthwestCheapest$350Average$546FlexibilityNo cancel feeOn-time63%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.