$258+ Cheap flights from Panama City, FL to San Antonio (ECP - SAT)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/7. Fares are subject to change and may not be available on all flights or dates of travel.
ECP — SAT
Oct 15 — Oct 221
Round-trip
1 adult, Economy
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Find cheap flights from Panama City to San Antonio with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Panama City to San Antonio
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Best
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Cheapest flights from Panama City to San AntonioExplore the most affordable flight options available from Panama City to San Antonio. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 15, 2026.
Explore the most affordable flight options available from Panama City to San Antonio. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 15, 2026.
This Southwest deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/77:50 am -
2 stops9h 35m
Sat 11/145:55 am -
1 stop7h 00m
Deal found 9/14![Southwest logo]()
$258
This United Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/104:50 pm -
1 stop6h 09m
Sat 12/125:45 pm -
1 stop3h 53m
Deal found 9/14![United Airlines logo]()
$268
This Southwest deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/107:55 am -
2 stops8h 25m
Sat 12/125:55 am -
1 stop7h 00m
Deal found 9/14![Southwest logo]()
$274
This United Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/74:55 pm -
1 stop5h 56m
Fri 11/134:19 pm -
1 stop5h 17m
Deal found 9/14![United Airlines logo]()
$285
This Southwest deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/710:05 am -
2 stops7h 20m
Fri 11/135:25 am -
1 stop5h 20m
Deal found 9/14![Southwest logo]()
$291
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/56:19 pm -
1 stop5h 49m
Tue 10/64:29 pm -
1 stop6h 49m
Deal found 9/10![Delta logo]()
$325
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/157:12 pm -
1 stop4h 47m
Sun 10/186:00 pm -
1 stop5h 53m
Deal found 9/14![American Airlines logo]()
$336
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/86:20 pm -
1 stop6h 13m
Sun 10/115:30 am -
1 stop5h 01m
Deal found 9/10![Delta logo]()
$346
This Southwest deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/84:00 pm -
1 stop7h 55m
Sun 10/1112:50 pm -
1 stop6h 25m
Deal found 9/15![Southwest logo]()
$365
Best flights from Panama City to San AntonioDiscover carefully curated flight deals from Panama City to San Antonio that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 15, 2026.
Discover carefully curated flight deals from Panama City to San Antonio that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 15, 2026.
This Southwest deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/77:50 am -
2 stops9h 35m
Sat 11/145:55 am -
1 stop7h 00m
Deal found 9/14![Southwest logo]()
$258
This United Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/74:55 pm -
1 stop5h 56m
Fri 11/134:19 pm -
1 stop5h 17m
Deal found 9/14![United Airlines logo]()
$285
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/245:30 pm -
1 stop4h 57m
Sun 2/2810:45 am -
1 stop7h 05m
Deal found 9/10![Delta logo]()
$346
This Southwest deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/710:05 am -
2 stops7h 20m
Fri 11/135:25 am -
1 stop5h 20m
Deal found 9/14![Southwest logo]()
$291
This Southwest deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/243:55 pm -
1 stop7h 15m
Sun 2/289:35 am -
2 stops7h 55m
Deal found 9/10![Southwest logo]()
$372
This Southwest deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/278:05 am -
1 stop6h 35m
Fri 10/305:25 am -
1 stop4h 50m
Deal found 9/13![Southwest logo]()
$387
This Southwest deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/84:00 pm -
1 stop7h 55m
Sun 10/1112:15 pm -
2 stops7h 00m
Deal found 9/15![Southwest logo]()
$392
Last-minute flights from Panama City to San AntonioDiscover last-minute flight deals from Panama City to San Antonio. Data last updated September 15, 2026 and is based on user searches.
Discover last-minute flight deals from Panama City to San Antonio. Data last updated September 15, 2026 and is based on user searches.
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/37:35 am -
1 stop7h 32m
Tue 10/64:29 pm -
1 stop6h 49m
Deal found 9/10![Delta logo]()
$372
This Delta deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/37:35 am -
1 stop5h 14m
Wed 10/145:30 am -
1 stop7h 05m
Deal found 9/11![Delta logo]()
$401
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/56:19 pm -
1 stop5h 49m
Tue 10/64:29 pm -
1 stop6h 49m
Deal found 9/10![Delta logo]()
$325
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/56:19 pm -
1 stop5h 49m
Wed 10/76:20 pm -
1 stop4h 58m
Deal found 9/10![Delta logo]()
$380
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/86:20 pm -
1 stop6h 13m
Sun 10/115:30 am -
1 stop5h 01m
Deal found 9/10![Delta logo]()
$346
This Southwest deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/84:00 pm -
1 stop7h 55m
Sun 10/1112:50 pm -
1 stop6h 25m
Deal found 9/15![Southwest logo]()
$365
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/97:35 pm -
1 stop4h 58m
Sun 10/115:30 am -
1 stop7h 20m
Deal found 9/10![Delta logo]()
$369
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/157:12 pm -
1 stop4h 47m
Sun 10/186:00 pm -
1 stop5h 53m
Deal found 9/14![American Airlines logo]()
$336
This Southwest deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/153:10 pm -
2 stops7h 55m
Sun 10/181:10 pm -
1 stop8h 25m
Deal found 9/14![Southwest logo]()
$398
This Southwest deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/278:05 am -
1 stop6h 35m
Fri 10/305:25 am -
1 stop4h 50m
Deal found 9/13![Southwest logo]()
$387
One-way flights from Panama City to San AntonioSearch for one-way flight options from Panama City to San Antonio. Find affordable one-way fares based on user searches. Data last updated September 15, 2026.
Search for one-way flight options from Panama City to San Antonio. Find affordable one-way fares based on user searches. Data last updated September 15, 2026.
This Delta deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/214:35 pm -
1 stop4h 39m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/12![Delta logo]()
$293
This Southwest deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/261:40 pm -
2 stops7h 15m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/13![Southwest logo]()
$298
This United Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/264:16 pm -
3 stops18h 27m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/13![United Airlines logo]()
$610
Find flight deals from Panama City to San Antonio
Discover tips and strategies to find the most affordable flight options for your journey from Panama City (ECP) to San Antonio (SAT). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 15, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $258 (Southwest) |
Popular in | October |
Cheapest in | May |
Average price | $446 |
Cheapflights Fare Finder
Customize your flight search to find flights from Panama City to San Antonio that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 15, 2026.
Use the filters below to find and compare flights from Panama City to San Antonio that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Panama CitySan Antonio
ECP Panama City NW Florida Beaches - SAT San Antonio
ECPSAT
Panama City NW Florida Beaches
Sat 11/7
7:50 am-5:25 pm
2 stops9h 35m
San Antonio
Sat 11/14
5:55 am-12:55 pm
1 stop7h 00m
$258
Panama CitySan Antonio
ECP Panama City NW Florida Beaches - SAT San Antonio
ECPSAT
Panama City NW Florida Beaches
Sat 11/7
4:55 pm-10:51 pm
1 stop5h 56m
San Antonio
Fri 11/13
4:19 pm-9:36 pm
1 stop5h 17m
$285
Panama CitySan Antonio
ECP Panama City NW Florida Beaches - SAT San Antonio
ECPSAT
Panama City NW Florida Beaches
Sat 11/7
10:05 am-5:25 pm
2 stops7h 20m
San Antonio
Fri 11/13
5:25 am-10:45 am
1 stop5h 20m
$291
Quickest round-trip
Panama CitySan Antonio
ECP Panama City NW Florida Beaches - SAT San Antonio
ECPSAT
Panama City NW Florida Beaches
Mon 9/21
4:35 pm-9:14 pm
1 stop4h 39m
San Antonio
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$293
Panama CitySan Antonio
ECP Panama City NW Florida Beaches - SAT San Antonio
ECPSAT
Panama City NW Florida Beaches
Sat 9/26
4:57 pm-10:51 pm
1 stop5h 54m
San Antonio
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$293
Panama CitySan Antonio
ECP Panama City NW Florida Beaches - SAT San Antonio
ECPSAT
Panama City NW Florida Beaches
Sat 9/26
1:40 pm-8:55 pm
2 stops7h 15m
San Antonio
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$298
Panama CitySan Antonio
ECP Panama City NW Florida Beaches - SAT San Antonio
ECPSAT
Panama City NW Florida Beaches
Wed 2/24
5:30 pm-10:27 pm
1 stop4h 57m
San Antonio
Sun 2/28
10:45 am-5:50 pm
1 stop7h 05m
$346
Panama CitySan Antonio
ECP Panama City NW Florida Beaches - SAT San Antonio
ECPSAT
Panama City NW Florida Beaches
Wed 2/24
3:55 pm-11:10 pm
1 stop7h 15m
San Antonio
Sun 2/28
9:35 am-5:30 pm
2 stops7h 55m
$372
Panama CitySan Antonio
ECP Panama City NW Florida Beaches - SAT San Antonio
ECPSAT
Panama City NW Florida Beaches
Tue 10/27
8:05 am-2:40 pm
1 stop6h 35m
San Antonio
Fri 10/30
5:25 am-10:15 am
1 stop4h 50m
$387
Panama CitySan Antonio
ECP Panama City NW Florida Beaches - SAT San Antonio
ECPSAT
Panama City NW Florida Beaches
Thu 10/8
4:00 pm-11:55 pm
1 stop7h 55m
San Antonio
Sun 10/11
12:15 pm-7:15 pm
2 stops7h 00m
$392
Sorted by cheapest first
Compare providers for flights from Panama City to San Antonio
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Panama City to San Antonio in September.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Panama City, Florida-San Antonio flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Panama City, Florida-San Antonio flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Panama City, Florida-San Antonio flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Panama City, Florida-San Antonio flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Panama City, Florida-San Antonio flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Panama City to San Antonio
Have a flexible travel schedule? Discover the best time to fly to San Antonio from Panama City with our price prediction graph.
ECP-SAT
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Panama City to San Antonio
Reviews of airlines servicing San Antonio
Get insights into the airlines that provide service to San Antonio. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Antonio. Reviews last updated September 15, 2026.
Read reviews from past customers who have flown Southwest,Delta, andUnited Airlines from Panama City to San Antonio. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Comfort
8.0
Boarding
8.1
Food
7.0
Overall
8.0
Crew
8.6
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreMike,Aug 2025
OKC - AUS
Comfort
8.0
Boarding
8.1
Food
7.0
Overall
8.0
Crew
8.6
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreMike,Aug 2025
OKC - AUS
Comfort
8.0
Boarding
8.1
Food
7.0
Overall
8.0
Crew
8.6
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreMike,Aug 2025
OKC - AUS
Comfort
8.0
Boarding
8.1
Food
7.0
Overall
8.0
Crew
8.6
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreMike,Aug 2025
OKC - AUS
Comfort
8.0
Boarding
8.1
Food
7.0
Overall
8.0
Crew
8.6
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreMike,Aug 2025
OKC - AUS
Related info for your journey
Find useful and relevant information for your journey from Panama City to San Antonio. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near San Antonio?
Book flights to San Antonio if you plan to visit one of these locationsNew Braunfels
Kerrville
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Panama City and San Antonio flights
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Top 4 airlines flying from Panama City to San Antonio
Discover the top 4 airlines that operate flights from Panama City to San Antonio. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 15, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$236 | Average$472 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$283 | Average$436 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$316 | Average$376 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$322 | Average$468 | FlexibilityNo cancel fee | On-time63% |