$159+ Cheap flights from Panama City, FL to San Antonio (ECP - SAT)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/14. Fares are subject to change and may not be available on all flights or dates of travel.
ECP — SAT
May 9 — May 161
Round-trip
1 adult, Economy
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Find cheap flights from Panama City to San Antonio with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Panama City to San Antonio
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Best
Last-minute
One-way
Cheapest flights from Panama City to San AntonioExplore the most affordable flight options available from Panama City to San Antonio. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 9, 2026.
Explore the most affordable flight options available from Panama City to San Antonio. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 9, 2026.
This Delta deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/112:43 pm
ECP
- SAT
1 stop5h 58m
Delta
Wed 6/175:25 am
SAT
- ECP
1 stop7h 01m
Delta
Deal found 4/4![Delta logo]()
$317
This Southwest deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/2910:10 am
ECP
- SAT
1 stop5h 40m
Southwest
Sat 5/91:20 pm
SAT
- ECP
1 stop7h 05m
Southwest
Deal found 4/6![Southwest logo]()
$321
This American Airlines deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/1211:43 am
ECP
- SAT
2 stops9h 15m
American Airlines
Sat 5/165:42 pm
SAT
- ECP
1 stop6h 04m
American Airlines
Deal found 4/6![American Airlines logo]()
$322
This Delta deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/206:46 pm
ECP
- SAT
1 stop6h 00m
Delta
Mon 5/46:20 am
SAT
- ECP
1 stop6h 21m
Delta
Deal found 4/6![Delta logo]()
$325
This Southwest deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/712:20 pm
ECP
- SAT
2 stops6h 50m
Southwest
Mon 5/111:00 pm
SAT
- ECP
2 stops8h 40m
Southwest
Deal found 4/6![Southwest logo]()
$327
This Southwest deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/225:05 pm
ECP
- SAT
1 stop4h 55m
Southwest
Sat 5/25:25 am
SAT
- ECP
2 stops7h 35m
Southwest
Deal found 4/6![Southwest logo]()
$330
This Delta deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/196:41 pm
ECP
- SAT
1 stop5h 49m
Delta
Tue 7/76:40 am
SAT
- ECP
1 stop5h 51m
Delta
Deal found 4/7![Delta logo]()
$337
This Southwest deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/812:20 pm
ECP
- SAT
2 stops6h 50m
Southwest
Mon 5/111:25 pm
SAT
- ECP
1 stop6h 25m
Southwest
Deal found 4/8![Southwest logo]()
$342
Best flights from Panama City to San AntonioDiscover carefully curated flight deals from Panama City to San Antonio that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 9, 2026.
Discover carefully curated flight deals from Panama City to San Antonio that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 9, 2026.
This American Airlines deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/293:17 pm
ECP
- SAT
1 stop6h 47m
American Airlines
Wed 9/306:35 am
SAT
- ECP
1 stop7h 37m
American Airlines
Deal found 4/8![American Airlines logo]()
$317
This Delta deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/112:43 pm
ECP
- SAT
1 stop5h 58m
Delta
Wed 6/175:25 am
SAT
- ECP
1 stop7h 01m
Delta
Deal found 4/4![Delta logo]()
$317
This Southwest deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/77:45 am
ECP
- SAT
1 stop8h 05m
Southwest
Mon 5/111:00 pm
SAT
- ECP
1 stop3h 15m
Southwest
Deal found 4/6![Southwest logo]()
$317
This United Airlines deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/86:30 am
ECP
- SAT
1 stop6h 46m
United Airlines
Mon 5/114:16 pm
SAT
- ECP
1 stop5h 49m
United Airlines
Deal found 4/8![United Airlines logo]()
$317
This Delta deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/189:23 am
ECP
- SAT
1 stop5h 53m
Delta
Mon 8/246:45 am
SAT
- ECP
1 stop5h 54m
Delta
Deal found 4/4![Delta logo]()
$317
This United Airlines deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/286:30 am
ECP
- SAT
1 stop6h 38m
United Airlines
Fri 5/16:02 pm
SAT
- ECP
1 stop4h 03m
United Airlines
Deal found 4/8![United Airlines logo]()
$325
This Southwest deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/297:55 am
ECP
- SAT
2 stops7h 55m
Southwest
Sat 5/91:20 pm
SAT
- ECP
1 stop7h 05m
Southwest
Deal found 4/6![Southwest logo]()
$326
This Delta deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/297:45 am
ECP
- SAT
1 stop5h 22m
Delta
Wed 9/305:30 pm
SAT
- ECP
1 stop5h 16m
Delta
Deal found 4/4![Delta logo]()
$317
This Delta deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/196:41 pm
ECP
- SAT
1 stop5h 49m
Delta
Mon 7/67:51 am
SAT
- ECP
1 stop4h 35m
Delta
Deal found 4/4![Delta logo]()
$317
Last-minute flights from Panama City to San AntonioDiscover last-minute flight deals from Panama City to San Antonio. Data last updated April 9, 2026 and is based on user searches.
Discover last-minute flight deals from Panama City to San Antonio. Data last updated April 9, 2026 and is based on user searches.
This Delta deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/206:46 pm
ECP
- SAT
1 stop6h 00m
Delta
Mon 5/46:20 am
SAT
- ECP
1 stop6h 21m
Delta
Deal found 4/6![Delta logo]()
$325
This Southwest deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/225:05 pm
ECP
- SAT
1 stop4h 55m
Southwest
Sat 5/25:25 am
SAT
- ECP
2 stops7h 35m
Southwest
Deal found 4/6![Southwest logo]()
$330
This Southwest deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/2910:10 am
ECP
- SAT
1 stop5h 40m
Southwest
Sat 5/91:20 pm
SAT
- ECP
1 stop7h 05m
Southwest
Deal found 4/6![Southwest logo]()
$321
This Southwest deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/712:20 pm
ECP
- SAT
2 stops6h 50m
Southwest
Mon 5/111:00 pm
SAT
- ECP
2 stops8h 40m
Southwest
Deal found 4/6![Southwest logo]()
$327
This Southwest deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/812:20 pm
ECP
- SAT
2 stops6h 50m
Southwest
Mon 5/111:25 pm
SAT
- ECP
1 stop6h 25m
Southwest
Deal found 4/8![Southwest logo]()
$342
This American Airlines deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/121:34 pm
ECP
- SAT
1 stop6h 31m
American Airlines
Sat 5/165:45 pm
SAT
- ECP
1 stop4h 28m
American Airlines
Deal found 4/4![American Airlines logo]()
$317
One-way flights from Panama City to San AntonioSearch for one-way flight options from Panama City to San Antonio. Find affordable one-way fares based on user searches. Data last updated April 9, 2026.
Search for one-way flight options from Panama City to San Antonio. Find affordable one-way fares based on user searches. Data last updated April 9, 2026.
This Delta deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/1411:40 am
ECP
- SAT
1 stop5h 36m
Delta
Deal found 4/4![Delta logo]()
$159
This American Airlines deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/204:40 pm
ECP
- SAT
1 stop6h 19m
American Airlines
Deal found 4/7![American Airlines logo]()
$199
This Southwest deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/2011:30 am
ECP
- SAT
2 stops7h 40m
Southwest
Deal found 4/7![Southwest logo]()
$204
This American Airlines deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/1410:50 am
ECP
- SAT
2 stops8h 54m
American Airlines
Deal found 4/4![American Airlines logo]()
$214
Find flight deals from Panama City to San Antonio
Discover tips and strategies to find the most affordable flight options for your journey from Panama City (ECP) to San Antonio (SAT). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated April 9, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $317 (Southwest) |
One-way from | $159 (Delta) |
Popular in | April |
Cheapest in | July |
Average price | $612 |
Cheapflights Fare Finder
Customize your flight search to find flights from Panama City to San Antonio that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 9, 2026.
Use the filters below to find and compare flights from Panama City to San Antonio that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Panama CitySan Antonio
ECP - SAT
ECPSAT
Panama City NW Florida Beaches
Tue 9/29
3:17 pm-10:04 pm
1 stop6h 47m
San Antonio
Wed 9/30
6:35 am-2:12 pm
1 stop7h 37m
$317
Panama CitySan Antonio
ECP - SAT
ECPSAT
Panama City NW Florida Beaches
Thu 6/11
2:43 pm-8:41 pm
1 stop5h 58m
San Antonio
Wed 6/17
5:25 am-12:26 pm
1 stop7h 01m
$317
Panama CitySan Antonio
ECP - SAT
ECPSAT
Panama City NW Florida Beaches
Thu 5/7
7:45 am-3:50 pm
1 stop8h 05m
San Antonio
Mon 5/11
1:00 pm-4:15 pm
1 stop3h 15m
$317
Panama CitySan Antonio
ECP - SAT
ECPSAT
Panama City NW Florida Beaches
Fri 5/8
6:30 am-1:16 pm
1 stop6h 46m
San Antonio
Mon 5/11
4:16 pm-10:05 pm
1 stop5h 49m
$317
Panama CitySan Antonio
ECP - SAT
ECPSAT
Panama City NW Florida Beaches
Tue 8/18
9:23 am-3:16 pm
1 stop5h 53m
San Antonio
Mon 8/24
6:45 am-12:39 pm
1 stop5h 54m
$317
Panama CitySan Antonio
ECP - SAT
ECPSAT
Panama City NW Florida Beaches
Tue 9/29
7:45 am-1:07 pm
1 stop5h 22m
San Antonio
Wed 9/30
5:30 pm-10:46 pm
1 stop5h 16m
$317
Quickest round-trip
Panama CitySan Antonio
ECP - SAT
ECPSAT
Panama City NW Florida Beaches
Fri 6/19
6:41 pm-12:30 am
1 stop5h 49m
San Antonio
Mon 7/6
7:51 am-12:26 pm
1 stop4h 35m
$317
Panama CitySan Antonio
ECP - SAT
ECPSAT
Panama City NW Florida Beaches
Tue 4/28
6:30 am-1:08 pm
1 stop6h 38m
San Antonio
Fri 5/1
6:02 pm-10:05 pm
1 stop4h 03m
$325
Panama CitySan Antonio
ECP - SAT
ECPSAT
Panama City NW Florida Beaches
Wed 4/29
7:55 am-3:50 pm
2 stops7h 55m
San Antonio
Sat 5/9
1:20 pm-8:25 pm
1 stop7h 05m
$326
Cheapest one-way
Quickest one-way
Panama CitySan Antonio
ECP - SAT
ECPSAT
Panama City NW Florida Beaches
Thu 5/14
11:40 am-5:16 pm
1 stop5h 36m
$159
Showing 1-10 of 13 resultsSorted by cheapest first
Compare providers for flights from Panama City to San Antonio
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Panama City to San Antonio in April.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy1 star | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Panama City, Florida-San Antonio flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Panama City, Florida-San Antonio flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Panama City, Florida-San Antonio flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Panama City, Florida-San Antonio flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Panama City, Florida-San Antonio flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Panama City to San Antonio
Have a flexible travel schedule? Discover the best time to fly to San Antonio from Panama City with our price prediction graph.
ECP-SAT
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Panama City to San Antonio
What is the cheapest month to book a flight from Panama City, Florida to San Antonio?
Currently, July is the cheapest month in which you can book a flight from Panama City, Florida to San Antonio (average of $76). Flying from Panama City, Florida to San Antonio in April is currently the most expensive (average of $234). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Panama City, Florida to San Antonio?
Reviews of airlines servicing San Antonio
Get insights into the airlines that provide service to San Antonio. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Antonio. Reviews last updated April 9, 2026.
Read reviews from past customers who have flown Southwest,Delta, andUnited Airlines from Panama City to San Antonio. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Comfort
8.0
Crew
8.6
Overall
8.0
Boarding
8.1
Food
7.0
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Comfort
8.0
Crew
8.6
Overall
8.0
Boarding
8.1
Food
7.0
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Comfort
8.0
Crew
8.6
Overall
8.0
Boarding
8.1
Food
7.0
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Comfort
8.0
Crew
8.6
Overall
8.0
Boarding
8.1
Food
7.0
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Comfort
8.0
Crew
8.6
Overall
8.0
Boarding
8.1
Food
7.0
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Related info for your journey
Find useful and relevant information for your journey from Panama City to San Antonio. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near San Antonio?
Book flights to San Antonio if you plan to visit one of these locationsNew Braunfels
Kerrville
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Panama City and San Antonio flights
Browse other Panama City and San Antonio flight options. Last updated on April 9, 2026.
Other flights from Panama City
Browse through other flights departing from Panama City. Flights are based on user searches made on Cheapflights and were last updated on April 9, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Other flights to San Antonio
Explore flights to San Antonio departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on April 9, 2026.
Top 4 airlines flying from Panama City to San Antonio
Discover the top 4 airlines that operate flights from Panama City to San Antonio. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 9, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$195 | Average$382 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$196 | Average$336 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$216 | Average$384 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$291 | Average$467 | FlexibilityNo cancel fee | On-time63% |