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$299+ Cheap flights from Knoxville (TYS) to Rome (ROM)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/12. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — ROM
oct. 11 — oct. 181
sáb. 10/11
sáb. 10/18
1 adult, Economy
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Cheap flight deals from Knoxville to Rome

Discover tips and strategies to find the most affordable flight options for your journey from Knoxville (TYS) to Rome (ROM). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated septiembre 11, 2025.

Round-trip from

$552
(FlightHub)

One-way from

$299
(Kiwi.com)

Popular in

May

Cheapest in

November

Average price

$1,117
From Knoxville McGhee Tyson to Rome (ROM)
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One-way flight from Knoxville McGhee Tyson to Rome (ROM)
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Highest demand for flights based on searches. 20% potential increase in price ($261 potential increase over avg. RT price).
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Cheapest flight prices on average. 4% potential price decrease ($47 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from Knoxville to Rome

Cheapest flights from Knoxville to Rome
Explore the most affordable flight options available from Knoxville to Rome. Find the lowest fares from popular airlines and budget airlines, with prices last updated on septiembre 11, 2025.

This FlightHub deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 11/129:50 amTYS - FCO
2 stops17h 05mAir Canada
vie. 11/211:15 pmFCO - TYS
2 stops40h 44mAir Canada
Deal found 9/10$552
This Delta deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 10/225:44 amTYS - FCO
1 stop19h 51mDelta
jue. 11/610:05 amFCO - TYS
1 stop17h 08mDelta
Deal found 9/8$575
This United Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 10/222:16 pmTYS - FCO
1 stop16h 49mUnited Airlines
jue. 11/67:05 amFCO - TYS
2 stops19h 15mUnited Airlines
Deal found 9/8$578
This Delta deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 10/266:12 amTYS - FCO
2 stops21h 33mDelta
vie. 11/712:00 pmFCO - TYS
2 stops29h 04mDelta
Deal found 9/8$579
This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 10/278:26 amTYS - FCO
2 stops18h 29mUnited Airlines
mié. 11/57:05 amFCO - TYS
2 stops22h 54mUnited Airlines
Deal found 9/10$583
This United Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 10/222:16 pmTYS - FCO
1 stop11h 59mUnited Airlines
mié. 11/57:00 amFCO - TYS
2 stops19h 33mUnited Airlines
Deal found 9/8$589
This Kiwi.com deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 10/277:15 amTYS - FCO
1 stop25h 25mMultiple Airlines
vie. 11/77:00 pmFCO - TYS
2 stops49h 05mMultiple Airlines
Deal found 9/11$590
This Kiwi.com deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 10/277:15 amTYS - FCO
1 stop25h 25mMultiple Airlines
sáb. 11/87:25 amFCO - TYS
2 stops36h 40mMultiple Airlines
Deal found 9/11$598
This United Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 10/272:25 pmTYS - FCO
2 stops18h 35mUnited Airlines
mar. 11/119:45 amFCO - TYS
2 stops20h 14mUnited Airlines
Deal found 9/11$599
This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 10/265:52 pmTYS - FCO
2 stops19h 23mUnited Airlines
mié. 11/57:05 amFCO - TYS
2 stops19h 28mUnited Airlines
Deal found 9/10$601
This United Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 10/279:50 amTYS - FCO
2 stops20h 10mUnited Airlines
vie. 11/79:45 amFCO - TYS
1 stop33h 32mUnited Airlines
Deal found 9/8$603

Cheapflights Fare Finder

 
Customize your flight search to find flights from Knoxville to Rome that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated septiembre 11, 2025.
Use the filters below to find and compare flights from Knoxville to Rome that are best for you.

Fly from

Knoxville

Fly to

Rome

Route

Depart

Return

Price

KnoxvilleRome

TYS - FCO

TYSFCO

Knoxville McGhee Tyson

dom. 3/1

7:00 am-7:45 am

1 stop18h 45m

Rome Fiumicino

mar. 3/31

11:30 am-1:18 pm

2 stops31h 48m

$552

KnoxvilleRome

TYS - FCO

TYSFCO

Knoxville McGhee Tyson

dom. 10/26

11:40 am-6:55 am

1 stop14h 15m

Rome Fiumicino

jue. 11/6

10:05 am-9:13 pm

1 stop17h 08m

$575

KnoxvilleRome

TYS - FCO

TYSFCO

Knoxville McGhee Tyson

dom. 3/1

7:58 am-9:00 am

1 stop19h 02m

Rome Fiumicino

mar. 3/31

1:10 pm-12:04 am

1 stop16h 54m

$575

KnoxvilleRome

TYS - FCO

TYSFCO

Knoxville McGhee Tyson

mié. 11/12

8:30 am-10:30 am

1 stop20h 00m

Rome Fiumicino

vie. 11/21

10:05 am-7:00 pm

1 stop14h 55m

$575

KnoxvilleRome

TYS - FCO

TYSFCO

Knoxville McGhee Tyson

mié. 10/22

8:50 am-9:15 am

2 stops18h 25m

Rome Fiumicino

jue. 11/6

9:45 am-8:33 pm

1 stop16h 48m

$575

KnoxvilleRome

TYS - FCO

TYSFCO

Knoxville McGhee Tyson

mié. 10/22

11:35 am-9:20 am

2 stops15h 45m

Rome Fiumicino

vie. 11/7

12:00 pm-11:04 am

2 stops29h 04m

$579

KnoxvilleRome

TYS - FCO

TYSFCO

Knoxville McGhee Tyson

dom. 10/26

11:40 am-6:55 am

1 stop14h 15m

Rome Fiumicino

vie. 11/7

12:00 pm-11:04 am

2 stops29h 04m

$579

KnoxvilleRome

TYS - FCO

TYSFCO

Knoxville McGhee Tyson

mié. 11/12

9:54 pm-2:30 pm

2 stops34h 36m

$299

KnoxvilleRome

TYS - FCO

TYSFCO

Knoxville McGhee Tyson

mar. 11/11

11:24 am-2:30 pm

2 stops21h 06m

$303

KnoxvilleRome

TYS - FCO

TYSFCO

Knoxville McGhee Tyson

mar. 11/11

2:50 pm-10:30 am

1 stop13h 40m

$453

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/9

Showing 1-10 of 12 results
1
2

Best time to book a flight from Knoxville to Rome

Have a flexible travel schedule? Discover the best time to fly to Rome from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to Rome

How far ahead should I book a flight from Knoxville to Rome?

Use this chart to determine the optimal time to book a round-trip flight from Knoxville to Rome. Price data was last updated on August 29, 2025.

Booking 79 days in advance of your planned departure date is, on average, the best time to get cheap flights from Knoxville to Rome. The general trend is that the closer you book to the departure date, the more expensive your flight will be.

What is the cheapest month to book a flight from Knoxville to Rome?

Currently, January is the cheapest month in which you can book a flight from Knoxville to Rome (average of $644). Flying from Knoxville to Rome in June is currently the most expensive (average of $1,133). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from TYS to ROM?

Find hourly flight availability from Knoxville to Rome. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated septiembre 11, 2025.

When flying from Knoxville to Rome, the time of day you fly usually plays a role in the price. Save by searching for a flight in the afternoon, which can drop the price by up to 18% versus a flight at noon.

How much does it cost to fly round-trip from Knoxville to Rome?

Reviews of airlines servicing Rome

Get insights into the airlines that provide service to Rome. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Rome. Reviews last updated septiembre 11, 2025.
Read through reviews of airlines operating flights from Knoxville to Rome, such as Delta, KLM, and United Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,960 reviews

Boarding

8.2

Crew

8.5

Entertainment

7.9

Overall

8.0

Comfort

7.9

Food

7.3

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,960 reviews
Delta
8.0
Very good
7,960 reviews

Boarding

8.2

Crew

8.5

Entertainment

7.9

Overall

8.0

Comfort

7.9

Food

7.3

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
KLM
7.8
Good
1,385 reviews
Delta
8.0
Very good
7,960 reviews

Boarding

8.2

Crew

8.5

Entertainment

7.9

Overall

8.0

Comfort

7.9

Food

7.3

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
United Airlines
7.4
Good
8,937 reviews
Delta
8.0
Very good
7,960 reviews

Boarding

8.2

Crew

8.5

Entertainment

7.9

Overall

8.0

Comfort

7.9

Food

7.3

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,960 reviews

Boarding

8.2

Crew

8.5

Entertainment

7.9

Overall

8.0

Comfort

7.9

Food

7.3

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
British Airways
6.7
Okay
7,361 reviews
Delta
8.0
Very good
7,960 reviews

Boarding

8.2

Crew

8.5

Entertainment

7.9

Overall

8.0

Comfort

7.9

Food

7.3

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Rome. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Knoxville to Rome?

    Most people fly from Knoxville McGhee Tyson (TYS) if they book a flight from Knoxville to Rome. On average, McGhee Tyson has 0 outbound flights to Rome per day from 4 airlines. Knoxville McGhee Tyson is conveniently located just 11.3 mi from Knoxville’s city center.

  • How long is the flight from Knoxville to Rome?

    United Airlines, KLM, and Delta can get you from Knoxville to Rome in just under 14h 15m. Your travel time can differ by up to 5h 45m. The distance from Knoxville to Rome is about 4908 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines flying from Knoxville to Rome round-trip?

    Flying on United Airlines is currently your cheapest option to Rome, with prices starting at $702. Additional round-trip tickets that might be worth considering are offered by Delta and British Airways, with the lowest prices starting at $761 and $765, respectively. You may be able to fly from Knoxville to Rome for 32% less than the average price by searching for these airlines.

  • Can I find deals for flights from Knoxville to Rome that include hotel bookings?

    Yes. In addition to deals on Knoxville to Rome flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Rome?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Rome.

  • Can I find deals for business class flights from Knoxville to Rome?

    Yes. Cheapflights offers flight deals from Knoxville to Rome by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Knoxville to Rome?

    Currently, January is the cheapest month in which you can book a flight from Knoxville to Rome (average of $644). Flying from Knoxville to Rome in June is currently the most expensive (average of $1,133). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Rome?

Book flights to Rome if you plan to visit one of these locations
Fiumicino
Gaeta
Montepulciano
Santa Marinella

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Top 4 airlines flying from Knoxville to Rome

Discover the top 4 airlines that operate flights from Knoxville to Rome. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated septiembre 11, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$702Average$1,144FlexibilityNo cancel feeOn-time69%
DeltaCheapest$761Average$1,063FlexibilityNo cancel feeOn-timeN/A
British AirwaysCheapest$765Average$957FlexibilityNo cancel feeOn-time70%
American AirlinesCheapest$806Average$1,459FlexibilityNo cancel feeOn-time71%

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