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$445+ Cheap flights from Knoxville (TYS) to Rome (ROM)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/24. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — ROM
Feb 20 — Feb 271
Fri 2/20
Fri 2/27
1 adult, Economy
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Cheap flight deals from Knoxville to Rome

Cheapest flights from Knoxville to Rome
Explore the most affordable flight options available from Knoxville to Rome. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 21, 2026.

This oojo deal was found by Cheapflights users on 1/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/244:02 pm
TYS
-
FCO
2 stops22h 38m
British Airways
Tue 3/312:15 pm
FCO
-
TYS
1 stop14h 33m
British Airways
Deal found 1/19$445
This American Airlines deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/166:10 am
TYS
-
FCO
1 stop20h 50m
American Airlines
Tue 3/31:10 pm
FCO
-
TYS
1 stop13h 47m
American Airlines
Deal found 1/20$457
This oojo deal was found by Cheapflights users on 1/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/176:10 am
TYS
-
FCO
2 stops24h 10m
British Airways
Tue 2/247:25 am
FCO
-
TYS
2 stops19h 15m
British Airways
Deal found 1/18$458
This Cheapflightsfares deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/166:10 am
TYS
-
FCO
2 stops33h 45m
British Airways
Tue 3/31:10 pm
FCO
-
TYS
1 stop13h 47m
British Airways
Deal found 1/20$459
This Iberia deal was found by Cheapflights users on 1/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Iberia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/234:02 pm
TYS
-
FCO
2 stops16h 53m
Multiple Airlines
Tue 3/37:30 am
FCO
-
TYS
2 stops19h 10m
Multiple Airlines
Deal found 1/19$464
This oojo deal was found by Cheapflights users on 1/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/166:10 am
TYS
-
FCO
1 stop20h 50m
British Airways
Mon 2/235:50 pm
FCO
-
TYS
2 stops32h 50m
British Airways
Deal found 1/19$467
This oojo deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/96:10 am
TYS
-
FCO
2 stops27h 45m
British Airways
Sun 3/158:35 pm
FCO
-
TYS
2 stops29h 30m
British Airways
Deal found 1/20$482
This Finnair deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Finnair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/912:21 pm
TYS
-
FCO
2 stops24h 34m
Multiple Airlines
Sun 3/156:40 pm
FCO
-
TYS
2 stops34h 11m
Multiple Airlines
Deal found 1/21$490

Find flight deals from Knoxville to Rome

Discover tips and strategies to find the most affordable flight options for your journey from Knoxville (TYS) to Rome (ROM). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated January 21, 2026.

Most accurate provider

Justfly.com
3 stars

Most trusted provider

Justfly.com
3 stars

Round-trip from

$445
(oojo)

Popular in

May

Cheapest in

December

Average price

$1,103
Provider with most accurate pricing for Knoxville McGhee Tyson-Rome (ROM) flight deals.
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Provider most trusted by Cheapflights users for Knoxville McGhee Tyson-Rome (ROM) flights.
Search Deals
From Knoxville McGhee Tyson to Rome (ROM)
Search Deals
Highest demand for flights based on searches. 18% potential increase in price ($218 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 4% potential price decrease ($46 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in January 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Knoxville to Rome that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 21, 2026.
Use the filters below to find and compare flights from Knoxville to Rome that are best for you.

Fly from

Knoxville

Fly to

Rome

Route

Depart

Return

Price

KnoxvilleRome

TYS - FCO

TYSFCO

Knoxville McGhee Tyson

Mon 2/16

6:10 am-9:55 pm

2 stops33h 45m

Rome Fiumicino

Tue 3/3

1:10 pm-8:57 pm

1 stop13h 47m

$459

KnoxvilleRome

TYS - FCO

TYSFCO

Knoxville McGhee Tyson

Mon 2/16

6:10 am-9:55 pm

2 stops33h 45m

Rome Fiumicino

Mon 2/23

5:50 pm-8:40 pm

2 stops32h 50m

$486

KnoxvilleRome

TYS - FCO

TYSFCO

Knoxville McGhee Tyson

Sat 2/21

6:45 am-7:45 am

1 stop19h 00m

Rome Fiumicino

Sat 2/28

9:40 am-10:49 am

2 stops31h 09m

$506

KnoxvilleRome

TYS - FCO

TYSFCO

Knoxville McGhee Tyson

Tue 2/17

5:00 pm-10:30 am

1 stop11h 30m

Rome Fiumicino

Tue 2/24

12:40 pm-11:52 pm

1 stop17h 12m

$507

KnoxvilleRome

TYS - FCO

TYSFCO

Knoxville McGhee Tyson

Mon 2/23

2:21 pm-8:30 am

1 stop12h 09m

Rome Fiumicino

Tue 3/3

11:00 am-7:29 pm

1 stop14h 29m

$507

KnoxvilleRome

TYS - FCO

TYSFCO

Knoxville McGhee Tyson

Tue 3/24

2:21 pm-5:55 pm

2 stops22h 34m

Rome Fiumicino

Tue 3/31

11:30 am-11:03 pm

2 stops41h 33m

$507

KnoxvilleRome

TYS - FCO

TYSFCO

Knoxville McGhee Tyson

Sat 2/28

7:25 pm-6:00 pm

2 stops16h 35m

Rome Fiumicino

Mon 3/9

9:45 am-8:47 pm

1 stop16h 02m

$527

KnoxvilleRome

TYS - FCO

TYSFCO

Knoxville McGhee Tyson

Tue 2/3

6:59 am-6:45 am

2 stops17h 46m

Rome Fiumicino

Sun 2/8

11:00 am-7:27 pm

1 stop14h 27m

$562

KnoxvilleRome

TYS - FCO

TYSFCO

Knoxville McGhee Tyson

Mon 2/16

9:49 am-10:30 am

1 stop18h 41m

Rome Fiumicino

Mon 2/23

12:40 pm-9:04 am

1 stop26h 24m

$588

KnoxvilleRome

TYS - FCO

TYSFCO

Knoxville McGhee Tyson

Mon 2/16

2:21 pm-11:00 am

2 stops14h 39m

Rome Fiumicino

Tue 3/3

1:05 pm-8:37 pm

2 stops37h 32m

$594

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/20

Compare providers for flights from Knoxville to Rome

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Knoxville to Rome in January.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
AranGrantPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
OvagoPrice Accuracy2 starsTrust Score*2 stars
Justfly.comPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Knoxville-Rome flights, users find the pricing of Justfly.com to be most consistent on Cheapflights vs. Justfly.com Users can find the same prices on Knoxville-Rome flight deals on Cheapflights vs. Justfly.com >95% of the time. Price accuracy is based on data collected from Knoxville-Rome flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Knoxville-Rome flights, Cheapflights users trust Justfly.com the most. Justfly.com has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Knoxville-Rome flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Knoxville to Rome

Have a flexible travel schedule? Discover the best time to fly to Rome from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to Rome

How far ahead should I book a flight from Knoxville to Rome?

Use this chart to determine the optimal time to book a round-trip flight from Knoxville to Rome. Price data was last updated on January 16, 2026.

Booking 7 days in advance of your planned departure date is, on average, the best time to get cheap flights from Knoxville to Rome. The general trend is that the closer you book to the departure date, the more expensive your flight will be.

What is the cheapest month to book a flight from Knoxville to Rome?

Currently, October is the cheapest month in which you can book a flight from Knoxville to Rome (average of $499). Flying from Knoxville to Rome in January is currently the most expensive (average of $1,073). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Knoxville to Rome?

Reviews of airlines servicing Rome

Get insights into the airlines that provide service to Rome. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Rome. Reviews last updated January 21, 2026.
Read through reviews of airlines operating flights from Knoxville to Rome, such as Delta, KLM, and United Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,087 reviews

Boarding

8.1

Overall

7.9

Crew

8.5

Entertainment

7.8

Food

7.2

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,087 reviews
Delta
7.9
Good
8,087 reviews

Boarding

8.1

Overall

7.9

Crew

8.5

Entertainment

7.8

Food

7.2

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
KLM
7.7
Good
1,442 reviews
Delta
7.9
Good
8,087 reviews

Boarding

8.1

Overall

7.9

Crew

8.5

Entertainment

7.8

Food

7.2

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
United Airlines
7.4
Good
9,190 reviews
Delta
7.9
Good
8,087 reviews

Boarding

8.1

Overall

7.9

Crew

8.5

Entertainment

7.8

Food

7.2

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,173 reviews
Delta
7.9
Good
8,087 reviews

Boarding

8.1

Overall

7.9

Crew

8.5

Entertainment

7.8

Food

7.2

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
British Airways
6.7
Okay
7,689 reviews
Delta
7.9
Good
8,087 reviews

Boarding

8.1

Overall

7.9

Crew

8.5

Entertainment

7.8

Food

7.2

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Rome. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Knoxville to Rome?

    Most people fly from Knoxville McGhee Tyson (TYS) if they book a flight from Knoxville to Rome. On average, McGhee Tyson has 0 outbound flights to Rome per day from 5 airlines. Knoxville McGhee Tyson is conveniently located just 11.3 mi from Knoxville’s city center.

  • How long is the flight from Knoxville to Rome?

    British Airways, United Airlines, and KLM can get you from Knoxville to Rome in just under 11h 30m. Your travel time can differ by up to 22h 15m. The distance from Knoxville to Rome is about 4908 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines flying from Knoxville to Rome round-trip?

    Flying on Delta is currently your cheapest option to Rome, with prices starting at $612. Additional round-trip tickets that might be worth considering are offered by United Airlines and Lufthansa, with the lowest prices starting at $620 and $716, respectively. You may be able to fly from Knoxville to Rome for 38% less than the average price by searching for these airlines.

  • Can I find deals for flights from Knoxville to Rome that include hotel bookings?

    Yes. In addition to deals on Knoxville to Rome flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Rome?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Rome.

  • Can I find deals for business class flights from Knoxville to Rome?

    Yes. Cheapflights offers flight deals from Knoxville to Rome by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Knoxville to Rome?

    Currently, October is the cheapest month in which you can book a flight from Knoxville to Rome (average of $499). Flying from Knoxville to Rome in January is currently the most expensive (average of $1,073). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Rome?

Book flights to Rome if you plan to visit one of these locations
Fiumicino
Montepulciano
Santa Marinella

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Top 5 airlines flying from Knoxville to Rome

Discover the top 5 airlines that operate flights from Knoxville to Rome. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 21, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$612Average$958FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$620Average$1,144FlexibilityNo cancel feeOn-time69%
LufthansaCheapest$716Average$966FlexibilityNo cancel feeOn-time76%
British AirwaysCheapest$765Average$874FlexibilityNo cancel feeOn-time70%
American AirlinesCheapest$779Average$1,226FlexibilityNo cancel feeOn-time71%

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