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$426+ Cheap flights from Knoxville (TYS) to Rome (ROM)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/6. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — ROM
Jan 3 — Jan 101
Sat 1/3
Sat 1/10
1 adult, Economy
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Cheap flight deals from Knoxville to Rome

Cheapest flights from Knoxville to Rome
Explore the most affordable flight options available from Knoxville to Rome. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 4, 2025.

This United Airlines deal was found by Cheapflights users on 12/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/162:30 pmTYS - FCO
1 stop12h 00mUnited Airlines
Mon 12/229:45 amFCO - TYS
2 stops20h 14mUnited Airlines
Deal found 12/3$769
This Trip.com deal was found by Cheapflights users on 12/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/161:52 pmTYS - FCO
1 stop11h 53mMultiple Airlines
Mon 12/2211:00 amFCO - TYS
1 stop14h 51mMultiple Airlines
Deal found 12/2$970
This Expedia deal was found by Cheapflights users on 12/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/52:58 pmTYS - FCO
2 stops37h 42mAer Lingus
Sun 12/78:15 pmFCO - TYS
2 stops31h 25mAer Lingus
Deal found 12/1$1,082
This United Airlines deal was found by Cheapflights users on 12/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/307:23 pmTYS - FCO
2 stops35h 17mUnited Airlines
Tue 1/67:05 amFCO - TYS
2 stops33h 52mUnited Airlines
Deal found 12/2$1,145
This Finnair deal was found by Cheapflights users on 12/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Finnair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/3012:18 pmTYS - FCO
1 stop16h 27mMultiple Airlines
Tue 1/611:00 amFCO - TYS
1 stop15h 56mMultiple Airlines
Deal found 12/2$1,226
This Mytrip deal was found by Cheapflights users on 12/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/57:15 amTYS - FCO
2 stops22h 10mMultiple Airlines
Sun 12/712:15 pmFCO - TYS
3 stops29h 40mMultiple Airlines
Deal found 12/1$1,312

Find flight deals from Knoxville to Rome

Discover tips and strategies to find the most affordable flight options for your journey from Knoxville (TYS) to Rome (ROM). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated December 4, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$460
(Gurufare)

One-way from

$426
(Kiwi.com)

Popular in

May

Cheapest in

December

Average price

$755
Provider with most accurate pricing for Knoxville McGhee Tyson-Rome (ROM) flight deals.
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Provider most trusted by Cheapflights users for Knoxville McGhee Tyson-Rome (ROM) flights.
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From Knoxville McGhee Tyson to Rome (ROM)
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One-way flight from Knoxville McGhee Tyson to Rome (ROM)
Search Deals
Highest demand for flights based on searches. 18% potential increase in price ($243 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 4% potential price decrease ($42 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Knoxville to Rome that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 4, 2025.
Use the filters below to find and compare flights from Knoxville to Rome that are best for you.

Fly from

Knoxville

Fly to

Rome

Route

Depart

Return

Price

KnoxvilleRome

TYS - FCO

TYSFCO

Knoxville McGhee Tyson

Fri 1/23

11:58 am-10:30 am

1 stop16h 32m

Rome Fiumicino

Tue 1/27

12:40 pm-9:21 am

1 stop26h 41m

$481

KnoxvilleRome

TYS - FCO

TYSFCO

Knoxville McGhee Tyson

Sun 1/18

9:30 am-8:30 am

1 stop17h 00m

Rome Fiumicino

Sun 1/25

12:45 pm-7:27 pm

2 stops36h 42m

$490

KnoxvilleRome

TYS - FCO

TYSFCO

Knoxville McGhee Tyson

Wed 3/11

2:21 pm-5:10 pm

2 stops21h 49m

Rome Fiumicino

Wed 3/18

7:05 am-8:47 pm

2 stops18h 42m

$494

KnoxvilleRome

TYS - FCO

TYSFCO

Knoxville McGhee Tyson

Sun 1/18

2:25 pm-8:30 am

1 stop12h 05m

Rome Fiumicino

Sun 1/25

7:05 am-7:27 pm

2 stops18h 22m

$497

KnoxvilleRome

TYS - FCO

TYSFCO

Knoxville McGhee Tyson

Sun 1/18

5:15 pm-4:55 pm

2 stops17h 40m

Rome Fiumicino

Sun 1/25

7:50 am-8:56 pm

2 stops19h 06m

$500

KnoxvilleRome

TYS - FCO

TYSFCO

Knoxville McGhee Tyson

Fri 1/23

11:07 am-7:55 am

2 stops14h 48m

Rome Fiumicino

Tue 1/27

7:05 am-7:27 pm

2 stops18h 22m

$507

KnoxvilleRome

TYS - FCO

TYSFCO

Knoxville McGhee Tyson

Mon 3/9

6:10 am-9:00 am

1 stop21h 50m

Rome Fiumicino

Sun 3/15

6:40 pm-11:54 pm

2 stops34h 14m

$518

KnoxvilleRome

TYS - FCO

TYSFCO

Knoxville McGhee Tyson

Tue 3/17

12:03 pm-8:45 am

2 stops15h 42m

Rome Fiumicino

Wed 3/25

11:00 am-11:51 pm

2 stops17h 51m

$580

KnoxvilleRome

TYS - FCO

TYSFCO

Knoxville McGhee Tyson

Fri 3/6

2:06 pm-12:50 am

3 stops28h 44m

$446

KnoxvilleRome

TYS - FCO

TYSFCO

Knoxville McGhee Tyson

Fri 5/22

12:55 pm-3:45 pm

2 stops20h 50m

$483

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/2

Showing 1-10 of 17 results
1
2

Compare providers for flights from Knoxville to Rome

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Knoxville to Rome in December.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
AranGrantPrice Accuracy2 starsTrust Score*3 stars
OvagoPrice Accuracy2 starsTrust Score*2 stars
eDreamsPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Knoxville-Rome flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Knoxville-Rome flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Knoxville-Rome flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Knoxville-Rome flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Knoxville-Rome flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Knoxville to Rome

Have a flexible travel schedule? Discover the best time to fly to Rome from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to Rome

How far ahead should I book a flight from Knoxville to Rome?

Use this chart to determine the optimal time to book a round-trip flight from Knoxville to Rome. Price data was last updated on November 28, 2025.

Booking 29 days in advance of your planned departure date is, on average, the best time to get cheap flights from Knoxville to Rome. The general trend is that the closer you book to the departure date, the more expensive your flight will be.

What is the cheapest month to book a flight from Knoxville to Rome?

Currently, November is the cheapest month in which you can book a flight from Knoxville to Rome (average of $587). Flying from Knoxville to Rome in June is currently the most expensive (average of $1,084). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from TYS to ROM?

Find hourly flight availability from Knoxville to Rome. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 4, 2025.

When flying from Knoxville to Rome, the time of day you fly usually plays a role in the price. Save by searching for a flight in the evening, which can drop the price by up to 19% versus a flight at noon.

How much does it cost to fly round-trip from Knoxville to Rome?

Reviews of airlines servicing Rome

Get insights into the airlines that provide service to Rome. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Rome. Reviews last updated December 4, 2025.
Read through reviews of airlines operating flights from Knoxville to Rome, such as Delta, KLM, and United Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,011 reviews

Food

7.3

Comfort

7.9

Entertainment

7.9

Overall

7.9

Boarding

8.1

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,011 reviews
Delta
7.9
Good
8,011 reviews

Food

7.3

Comfort

7.9

Entertainment

7.9

Overall

7.9

Boarding

8.1

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
KLM
7.7
Good
1,428 reviews
Delta
7.9
Good
8,011 reviews

Food

7.3

Comfort

7.9

Entertainment

7.9

Overall

7.9

Boarding

8.1

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
United Airlines
7.4
Good
9,063 reviews
Delta
7.9
Good
8,011 reviews

Food

7.3

Comfort

7.9

Entertainment

7.9

Overall

7.9

Boarding

8.1

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,043 reviews
Delta
7.9
Good
8,011 reviews

Food

7.3

Comfort

7.9

Entertainment

7.9

Overall

7.9

Boarding

8.1

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
British Airways
6.7
Okay
7,559 reviews
Delta
7.9
Good
8,011 reviews

Food

7.3

Comfort

7.9

Entertainment

7.9

Overall

7.9

Boarding

8.1

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Rome. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Knoxville to Rome?

    Most people fly from Knoxville McGhee Tyson (TYS) if they book a flight from Knoxville to Rome. On average, McGhee Tyson has 0 outbound flights to Rome per day from 5 airlines. Knoxville McGhee Tyson is conveniently located just 11.3 mi from Knoxville’s city center.

  • How long is the flight from Knoxville to Rome?

    Delta, United Airlines, and Lufthansa can get you from Knoxville to Rome in just under 12h 05m. Your travel time can differ by up to 4h 55m. The distance from Knoxville to Rome is about 4908 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines flying from Knoxville to Rome round-trip?

    Flying on Delta is currently your cheapest option to Rome, with prices starting at $612. Additional round-trip tickets that might be worth considering are offered by United Airlines and Lufthansa, with the lowest prices starting at $620 and $716, respectively. You may be able to fly from Knoxville to Rome for 40% less than the average price by searching for these airlines.

  • Can I find deals for flights from Knoxville to Rome that include hotel bookings?

    Yes. In addition to deals on Knoxville to Rome flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Rome?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Rome.

  • Can I find deals for business class flights from Knoxville to Rome?

    Yes. Cheapflights offers flight deals from Knoxville to Rome by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Knoxville to Rome?

    Currently, November is the cheapest month in which you can book a flight from Knoxville to Rome (average of $587). Flying from Knoxville to Rome in June is currently the most expensive (average of $1,084). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Rome?

Book flights to Rome if you plan to visit one of these locations
Fiumicino
Montepulciano
Santa Marinella

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Top 5 airlines flying from Knoxville to Rome

Discover the top 5 airlines that operate flights from Knoxville to Rome. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 4, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$612Average$966FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$620Average$1,144FlexibilityNo cancel feeOn-time69%
LufthansaCheapest$716Average$976FlexibilityNo cancel feeOn-time76%
British AirwaysCheapest$765Average$874FlexibilityNo cancel feeOn-time70%
American AirlinesCheapest$805Average$1,459FlexibilityNo cancel feeOn-time71%

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