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$375+ Cheap flights from Knoxville (TYS) to Rome (ROM)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/10. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — ROM
Feb 6 — Feb 131
Fri 2/6
Fri 2/13
1 adult, Economy
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Cheap flight deals from Knoxville to Rome

Discover tips and strategies to find the most affordable flight options for your journey from Knoxville (TYS) to Rome (ROM). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated January 7, 2026.

Most accurate provider

Justfly.com
3 stars

Most trusted provider

Justfly.com
3 stars

Round-trip from

$454
(American Airlines)

One-way from

$375
(Kiwi.com)

Popular in

May

Cheapest in

December

Average price

$1,103
Provider with most accurate pricing for Knoxville McGhee Tyson-Rome (ROM) flight deals.
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Provider most trusted by Cheapflights users for Knoxville McGhee Tyson-Rome (ROM) flights.
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From Knoxville McGhee Tyson to Rome (ROM)
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One-way flight from Knoxville McGhee Tyson to Rome (ROM)
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Highest demand for flights based on searches. 19% potential increase in price ($241 potential increase over avg. RT price).
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Cheapest flight prices on average. 4% potential price decrease ($47 potential savings vs. average RT price).
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Average for round-trip flights in January 2026
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Find flight deals from Knoxville to Rome

Cheapest flights from Knoxville to Rome
Explore the most affordable flight options available from Knoxville to Rome. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 7, 2026.

This oojo deal was found by Cheapflights users on 1/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/12:19 pmTYS - FCO
2 stops18h 11mBritish Airways
Tue 2/171:10 pmFCO - TYS
1 stop13h 47mBritish Airways
Deal found 1/5$446
This American Airlines deal was found by Cheapflights users on 1/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/12:19 pmTYS - FCO
2 stops18h 11mAmerican Airlines
Tue 2/171:10 pmFCO - TYS
1 stop13h 47mAmerican Airlines
Deal found 1/6$454
This KLM deal was found by Cheapflights users on 1/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/14:06 pmTYS - FCO
1 stop12h 24mKLM
Tue 2/1712:40 pmFCO - TYS
1 stop17h 12mKLM
Deal found 1/6$458
This KLM deal was found by Cheapflights users on 1/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/311:58 amTYS - FCO
2 stops15h 47mKLM
Tue 2/1012:40 pmFCO - TYS
1 stop17h 05mKLM
Deal found 1/6$462
This Delta deal was found by Cheapflights users on 1/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/45:00 pmTYS - FCO
2 stops18h 25mDelta
Wed 2/1112:40 pmFCO - TYS
1 stop17h 05mDelta
Deal found 1/5$477
This oojo deal was found by Cheapflights users on 1/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/94:02 pmTYS - FCO
2 stops24h 53mBritish Airways
Sun 3/158:35 pmFCO - TYS
2 stops29h 30mBritish Airways
Deal found 1/6$483
This oojo deal was found by Cheapflights users on 1/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/126:10 amTYS - FCO
2 stops32h 00mBritish Airways
Mon 3/305:55 pmFCO - TYS
2 stops33h 29mBritish Airways
Deal found 1/5$484
This United Airlines deal was found by Cheapflights users on 1/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/207:25 pmTYS - FCO
1 stop31h 05mUnited Airlines
Sun 3/11:15 pmFCO - TYS
2 stops50h 57mUnited Airlines
Deal found 1/5$488
This FlightHub deal was found by Cheapflights users on 1/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/41:59 pmTYS - FCO
2 stops16h 26mLufthansa
Wed 2/117:05 amFCO - TYS
2 stops18h 22mLufthansa
Deal found 1/5$498

Cheapflights Fare Finder

 
Customize your flight search to find flights from Knoxville to Rome that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 7, 2026.
Use the filters below to find and compare flights from Knoxville to Rome that are best for you.

Fly from

Knoxville

Fly to

Rome

Route

Depart

Return

Price

KnoxvilleRome

TYS - FCO

TYSFCO

Knoxville McGhee Tyson

Tue 2/3

11:58 am-9:45 am

2 stops15h 47m

Rome Fiumicino

Tue 2/10

12:40 pm-11:45 pm

1 stop17h 05m

$462

KnoxvilleRome

TYS - FCO

TYSFCO

Knoxville McGhee Tyson

Fri 2/20

7:25 pm-8:30 am

1 stop31h 05m

Rome Fiumicino

Sun 3/1

1:15 pm-10:12 am

2 stops50h 57m

$488

KnoxvilleRome

TYS - FCO

TYSFCO

Knoxville McGhee Tyson

Fri 2/20

6:45 am-7:45 am

1 stop19h 00m

Rome Fiumicino

Fri 2/27

9:45 am-11:44 pm

2 stops19h 59m

$506

KnoxvilleRome

TYS - FCO

TYSFCO

Knoxville McGhee Tyson

Thu 1/29

2:19 pm-12:00 pm

2 stops15h 41m

Rome Fiumicino

Mon 2/2

6:50 pm-10:09 pm

2 stops33h 19m

$525

KnoxvilleRome

TYS - FCO

TYSFCO

Knoxville McGhee Tyson

Wed 2/4

2:37 pm-10:30 am

1 stop13h 53m

Rome Fiumicino

Wed 2/11

12:40 pm-11:45 pm

1 stop17h 05m

$558

KnoxvilleRome

TYS - FCO

TYSFCO

Knoxville McGhee Tyson

Sun 3/15

6:10 am-4:55 pm

2 stops29h 45m

Rome Fiumicino

Sun 3/22

6:50 pm-9:05 pm

2 stops31h 15m

$650

KnoxvilleRome

TYS - FCO

TYSFCO

Knoxville McGhee Tyson

Thu 1/29

9:30 am-8:30 am

1 stop17h 00m

Rome Fiumicino

Mon 2/2

11:15 am-2:49 pm

2 stops33h 34m

$688

KnoxvilleRome

TYS - FCO

TYSFCO

Knoxville McGhee Tyson

Sun 5/10

11:27 am-11:40 am

3 stops42h 13m

$375

KnoxvilleRome

TYS - FCO

TYSFCO

Knoxville McGhee Tyson

Sun 5/10

2:15 pm-12:05 pm

1 stop15h 50m

$427

KnoxvilleRome

TYS - FCO

TYSFCO

Knoxville McGhee Tyson

Fri 7/3

6:21 am-7:05 am

1 stop18h 44m

$492

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/5

Showing 1-10 of 13 results
1
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Compare providers for flights from Knoxville to Rome

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Knoxville to Rome in January.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
AranGrantPrice Accuracy2 starsTrust Score*3 stars
OvagoPrice Accuracy2 starsTrust Score*2 stars
eDreamsPrice Accuracy3 starsTrust Score*3 stars
Justfly.comPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Knoxville-Rome flights, users find the pricing of Justfly.com to be most consistent on Cheapflights vs. Justfly.com Users can find the same prices on Knoxville-Rome flight deals on Cheapflights vs. Justfly.com >95% of the time. Price accuracy is based on data collected from Knoxville-Rome flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Knoxville-Rome flights, Cheapflights users trust Justfly.com the most. Justfly.com has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Knoxville-Rome flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Knoxville to Rome

Have a flexible travel schedule? Discover the best time to fly to Rome from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to Rome

What is the cheapest month to book a flight from Knoxville to Rome?

Currently, November is the cheapest month in which you can book a flight from Knoxville to Rome (average of $587). Flying from Knoxville to Rome in January is currently the most expensive (average of $1,073). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Rome

Get insights into the airlines that provide service to Rome. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Rome. Reviews last updated January 7, 2026.
Read through reviews of airlines operating flights from Knoxville to Rome, such as Delta, KLM, and United Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,021 reviews

Overall

7.9

Entertainment

7.8

Comfort

7.9

Boarding

8.1

Food

7.2

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,021 reviews
Delta
7.9
Good
8,021 reviews

Overall

7.9

Entertainment

7.8

Comfort

7.9

Boarding

8.1

Food

7.2

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
KLM
7.7
Good
1,434 reviews
Delta
7.9
Good
8,021 reviews

Overall

7.9

Entertainment

7.8

Comfort

7.9

Boarding

8.1

Food

7.2

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
United Airlines
7.4
Good
9,138 reviews
Delta
7.9
Good
8,021 reviews

Overall

7.9

Entertainment

7.8

Comfort

7.9

Boarding

8.1

Food

7.2

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,090 reviews
Delta
7.9
Good
8,021 reviews

Overall

7.9

Entertainment

7.8

Comfort

7.9

Boarding

8.1

Food

7.2

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
British Airways
6.7
Okay
7,657 reviews
Delta
7.9
Good
8,021 reviews

Overall

7.9

Entertainment

7.8

Comfort

7.9

Boarding

8.1

Food

7.2

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Rome. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Knoxville to Rome?

    Most people fly from Knoxville McGhee Tyson (TYS) if they book a flight from Knoxville to Rome. On average, McGhee Tyson has 0 outbound flights to Rome per day from 5 airlines. Knoxville McGhee Tyson is conveniently located just 11.3 mi from Knoxville’s city center.

  • How long is the flight from Knoxville to Rome?

    KLM and United Airlines can get you from Knoxville to Rome in just under 15h 47m. Your travel time can differ by up to 15h 18m. The distance from Knoxville to Rome is about 4908 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines flying from Knoxville to Rome round-trip?

    Flying on Delta is currently your cheapest option to Rome, with prices starting at $612. Additional round-trip tickets that might be worth considering are offered by United Airlines and Lufthansa, with the lowest prices starting at $620 and $716, respectively. You may be able to fly from Knoxville to Rome for 39% less than the average price by searching for these airlines.

  • Can I find deals for flights from Knoxville to Rome that include hotel bookings?

    Yes. In addition to deals on Knoxville to Rome flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Rome?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Rome.

  • Can I find deals for business class flights from Knoxville to Rome?

    Yes. Cheapflights offers flight deals from Knoxville to Rome by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Knoxville to Rome?

    Currently, November is the cheapest month in which you can book a flight from Knoxville to Rome (average of $587). Flying from Knoxville to Rome in January is currently the most expensive (average of $1,073). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Rome?

Book flights to Rome if you plan to visit one of these locations
Fiumicino
Montepulciano
Santa Marinella

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Top 5 airlines flying from Knoxville to Rome

Discover the top 5 airlines that operate flights from Knoxville to Rome. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 7, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$612Average$966FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$620Average$1,144FlexibilityNo cancel feeOn-time69%
LufthansaCheapest$716Average$976FlexibilityNo cancel feeOn-time76%
British AirwaysCheapest$765Average$874FlexibilityNo cancel feeOn-time70%
American AirlinesCheapest$805Average$1,459FlexibilityNo cancel feeOn-time71%

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