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Roanoke

$212+ Cheap flights from South Carolina to Roanoke (ROA)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/16. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — ROA
Apr 18 — Apr 251
Sat 4/18
Sat 4/25
1 adult, Economy
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Cheap flight deals from South Carolina to Roanoke

Cheapest flights from South Carolina to Roanoke
Explore the most affordable flight options available from South Carolina to Roanoke. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 19, 2026.

This American Airlines deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/146:10 am
CHS
-
ROA
1 stop4h 46m
American Airlines
Tue 4/2112:58 pm
ROA
-
CHS
1 stop5h 46m
American Airlines
Deal found 3/15$289
This American Airlines deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/316:00 am
CAE
-
ROA
1 stop5h 34m
American Airlines
Sat 4/48:00 pm
ROA
-
CAE
1 stop3h 57m
American Airlines
Deal found 3/16$289
This American Airlines deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/38:10 pm
SAV
-
ROA
1 stop3h 35m
American Airlines
Tue 4/712:58 pm
ROA
-
SAV
1 stop5h 18m
American Airlines
Deal found 3/15$294
This American Airlines deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/3111:58 am
CHS
-
ROA
1 stop4h 35m
American Airlines
Sat 4/48:00 pm
ROA
-
CHS
1 stop3h 55m
American Airlines
Deal found 3/16$299
This American Airlines deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/85:00 am
CAE
-
ROA
1 stop5h 38m
American Airlines
Wed 4/156:00 am
ROA
-
CAE
1 stop4h 13m
American Airlines
Deal found 3/17$299
This Delta deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/137:44 pm
CHS
-
ROA
1 stop4h 41m
Delta
Mon 4/207:50 pm
ROA
-
CHS
1 stop4h 32m
Delta
Deal found 3/19$309
This Delta deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/97:00 am
SAV
-
ROA
1 stop3h 35m
Delta
Sun 7/127:50 pm
ROA
-
SAV
1 stop4h 14m
Delta
Deal found 3/16$309
This Delta deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/85:27 am
CHS
-
ROA
1 stop5h 00m
Delta
Tue 4/147:50 pm
ROA
-
CHS
1 stop4h 00m
Delta
Deal found 3/19$314
This United Airlines deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/26:00 am
CHS
-
ROA
1 stop3h 49m
United Airlines
Mon 4/610:34 am
ROA
-
CHS
1 stop4h 19m
United Airlines
Deal found 3/17$319
This United Airlines deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/35:40 am
SAV
-
ROA
1 stop4h 09m
United Airlines
Tue 4/710:34 am
ROA
-
SAV
1 stop4h 06m
United Airlines
Deal found 3/19$319
This Delta deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/85:27 am
CHS
-
ROA
1 stop5h 00m
Delta
Fri 4/177:50 pm
ROA
-
CHS
1 stop4h 32m
Delta
Deal found 3/18$321
This American Airlines deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/278:11 pm
CAE
-
ROA
1 stop3h 34m
American Airlines
Sat 3/286:00 am
ROA
-
CAE
1 stop4h 37m
American Airlines
Deal found 3/17$329

Find flight deals from South Carolina to Roanoke

Keep the following information in mind while searching for South Carolina to Roanoke flight deals. Data was last updated March 19, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$289
(American Airlines)

One-way from

$212
(Kiwi.com)
Provider with most accurate pricing for Myrtle Beach Intl-Roanoke flight deals.
Search Deals
Provider most trusted by Cheapflights users for Myrtle Beach Intl-Roanoke flights.
Search Deals
From South Carolina to Roanoke
Search Deals
One-way flight from South Carolina to Roanoke
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from South Carolina to Roanoke that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 19, 2026.
Use the filters below to find and compare flights from South Carolina to Roanoke that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

CharlestonRoanoke

CHS - ROA

CHSROA

Charleston

Tue 4/14

6:10 am-10:56 am

1 stop4h 46m

Roanoke

Tue 4/21

12:58 pm-6:44 pm

1 stop5h 46m

$289

ColumbiaRoanoke

CAE - ROA

CAEROA

Columbia Metropolitan

Tue 3/31

6:00 am-11:34 am

1 stop5h 34m

Roanoke

Sat 4/4

8:00 pm-11:57 pm

1 stop3h 57m

$289

ColumbiaRoanoke

CAE - ROA

CAEROA

Columbia Metropolitan

Wed 4/8

5:00 am-10:38 am

1 stop5h 38m

Roanoke

Wed 4/15

6:00 am-10:13 am

1 stop4h 13m

$299

CharlestonRoanoke

CHS - ROA

CHSROA

Charleston

Wed 4/8

10:00 am-2:13 pm

1 stop4h 13m

Roanoke

Tue 4/14

2:55 pm-6:59 pm

1 stop4h 04m

$309

SavannahRoanoke

SAV - ROA

SAVROA

Savannah/Hilton Head

Thu 7/9

5:30 am-10:35 am

1 stop5h 05m

Roanoke

Sun 7/12

7:50 pm-12:04 am

1 stop4h 14m

$309

CharlestonRoanoke

CHS - ROA

CHSROA

Charleston

Wed 4/8

5:27 am-10:27 am

1 stop5h 00m

Roanoke

Tue 4/14

7:50 pm-11:50 pm

1 stop4h 00m

$314

SavannahRoanoke

SAV - ROA

SAVROA

Savannah/Hilton Head

Fri 4/3

5:40 am-9:49 am

1 stop4h 09m

Roanoke

Tue 4/7

10:34 am-2:40 pm

1 stop4h 06m

$319

CharlestonRoanoke

CHS - ROA

CHSROA

Charleston

Fri 4/24

7:44 pm-12:25 am

1 stop4h 41m

Roanoke

Sun 4/26

6:00 am-10:09 am

1 stop4h 09m

$348

CharlestonRoanoke

CHS - ROA

CHSROA

Charleston

Fri 8/14

10:00 am-2:18 pm

1 stop4h 18m

Roanoke

Tue 8/18

6:15 am-10:02 am

1 stop3h 47m

$369

SavannahRoanoke

SAV - ROA

SAVROA

Savannah/Hilton Head

Sat 8/22

9:50 am-2:18 pm

1 stop4h 28m

Roanoke

Wed 8/26

10:30 am-2:47 pm

1 stop4h 17m

$369

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/17

Showing 1-10 of 50 resultsSorted by cheapest first
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Best time to book a flight from South Carolina to Roanoke

Have a flexible travel schedule? Discover the best time to fly to Roanoke from South Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to Roanoke
No data available for this route at this time. Please check back soon.

Related info for your journey

Find useful and relevant information for your journey from South Carolina to Roanoke. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Roanoke from South Carolina?

    Most people fly into Roanoke (ROA) if they book a flight to Roanoke from South Carolina. Roanoke is conveniently located just 4.2 mi from Roanoke’s city center.

  • How long is the flight from South Carolina to Roanoke?

    Departing from South Carolina to Roanoke will take you 4h 18m. South Carolina and Roanoke are separated by a distance of 306 mi. This flight may include one or multiple stops.

  • What are the most popular routes from South Carolina to Roanoke?

    While some choose either Charleston - Roanoke or Columbia Metropolitan - Roanoke, Charlotte Douglas - Roanoke is the most popular route from South Carolina to Roanoke.

  • Can I find deals for flights from South Carolina to Roanoke that include hotel bookings?

    Yes. In addition to deals on South Carolina to Roanoke flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to Roanoke?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Roanoke.

  • Can I find deals for business class flights from South Carolina to Roanoke?

    Yes. Cheapflights offers flight deals from South Carolina to Roanoke by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near Roanoke?

Book flights to Roanoke if you plan to visit one of these locations
Salem
Radford
Blacksburg
Christiansburg

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Alternative routes for South Carolina to Roanoke

See prices for flight routes from nearby airports that may be better suited for you.
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Top airline flying from South Carolina to Roanoke

Discover the top airline that operate flights from South Carolina to Roanoke. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 19, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$218Average$320FlexibilityNo cancel feeOn-time71%

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