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Roanoke

$190+ Cheap flights from South Carolina to Roanoke (ROA)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/10. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — ROA
Jan 11 — Jan 181
Sun 1/11
Sun 1/18
1 adult, Economy
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Cheap flight deals from South Carolina to Roanoke

Cheapest flights from South Carolina to Roanoke
Explore the most affordable flight options available from South Carolina to Roanoke. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 12, 2025.

This United Airlines deal was found by Cheapflights users on 12/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/132:51 pmCHS - ROA
1 stop4h 05mUnited Airlines
Mon 12/1510:20 amROA - CHS
1 stop4h 50mUnited Airlines
Deal found 12/9$319
This American Airlines deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/208:08 pmCHS - ROA
1 stop3h 31mAmerican Airlines
Fri 1/29:08 amROA - CHS
1 stop5h 10mAmerican Airlines
Deal found 12/11$339
This American Airlines deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/265:10 amCHS - ROA
1 stop3h 32mAmerican Airlines
Tue 12/302:47 pmROA - CHS
1 stop4h 41mAmerican Airlines
Deal found 12/10$367
This American Airlines deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/251:10 pmCLT - ROA
Nonstop1h 12mAmerican Airlines
Mon 12/296:00 amROA - CLT
Nonstop1h 34mAmerican Airlines
Deal found 12/10$405
This United Airlines deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/2510:00 amCLT - ROA
1 stop4h 16mUnited Airlines
Mon 12/297:55 pmROA - CLT
1 stop4h 04mUnited Airlines
Deal found 12/10$425
This American Airlines deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/242:35 pmCAE - ROA
1 stop4h 46mAmerican Airlines
Sat 12/272:47 pmROA - CAE
1 stop3h 04mAmerican Airlines
Deal found 12/10$443
This United Airlines deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/2611:40 amCHS - ROA
1 stop5h 21mUnited Airlines
Tue 12/3010:32 amROA - CHS
1 stop4h 50mUnited Airlines
Deal found 12/11$460
This American Airlines deal was found by Cheapflights users on 12/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/178:20 pmCLT - ROA
Nonstop1h 17mAmerican Airlines
Mon 12/227:07 pmROA - CLT
Nonstop1h 27mAmerican Airlines
Deal found 12/9$467
This United Airlines deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/267:37 pmCAE - ROA
2 stops21h 24mUnited Airlines
Tue 12/306:15 amROA - CAE
1 stop3h 50mUnited Airlines
Deal found 12/11$473
This United Airlines deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/207:44 pmCLT - ROA
1 stop3h 46mUnited Airlines
Thu 1/810:15 amROA - CLT
1 stop23h 48mUnited Airlines
Deal found 12/10$482
This American Airlines deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/263:15 pmCLT - ROA
1 stop5h 12mAmerican Airlines
Tue 12/308:14 amROA - CLT
1 stop4h 12mAmerican Airlines
Deal found 12/10$487
This American Airlines deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/193:15 pmCLT - ROA
1 stop5h 09mAmerican Airlines
Sun 12/216:00 amROA - CLT
Nonstop1h 34mAmerican Airlines
Deal found 12/11$525

Find flight deals from South Carolina to Roanoke

Keep the following information in mind while searching for South Carolina to Roanoke flight deals. Data was last updated December 12, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$253
(United Airlines)

One-way from

$190
(Delta)
Provider with most accurate pricing for Myrtle Beach Intl-Roanoke flight deals.
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Provider most trusted by Cheapflights users for Myrtle Beach Intl-Roanoke flights.
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From South Carolina to Roanoke
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One-way flight from South Carolina to Roanoke
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Cheapflights Fare Finder

 
Customize your flight search to find flights from South Carolina to Roanoke that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 12, 2025.
Use the filters below to find and compare flights from South Carolina to Roanoke that are best for you.

Fly from

South Carolina

Fly to

Roanoke

Route

Depart

Return

Price

CharlestonRoanoke

CHS - ROA

CHSROA

Charleston

Sat 2/7

2:58 pm-7:31 pm

1 stop4h 33m

Roanoke

Tue 2/10

6:45 am-12:32 pm

1 stop5h 47m

$253

SavannahRoanoke

SAV - ROA

SAVROA

Savannah/Hilton Head

Sat 1/31

9:45 am-2:09 pm

1 stop4h 24m

Roanoke

Tue 2/3

10:15 am-2:47 pm

1 stop4h 32m

$253

ColumbiaRoanoke

CAE - ROA

CAEROA

Columbia Metropolitan

Wed 1/28

8:00 am-2:46 pm

1 stop6h 46m

Roanoke

Sat 1/31

2:55 pm-6:55 pm

1 stop4h 00m

$279

ColumbiaRoanoke

CAE - ROA

CAEROA

Columbia Metropolitan

Wed 3/11

8:44 am-2:31 pm

1 stop5h 47m

Roanoke

Sat 3/14

7:37 pm-11:54 pm

1 stop4h 17m

$323

CharlestonRoanoke

CHS - ROA

CHSROA

Charleston

Thu 1/1

10:00 am-2:16 pm

1 stop4h 16m

Roanoke

Thu 1/8

12:40 pm-8:02 pm

1 stop7h 22m

$344

CharlestonRoanoke

CHS - ROA

CHSROA

Charleston

Fri 12/26

5:10 am-8:42 am

1 stop3h 32m

Roanoke

Tue 12/30

2:47 pm-7:28 pm

1 stop4h 41m

$367

CharlotteRoanoke

CLT - ROA

CLTROA

Charlotte Douglas

Thu 12/25

1:10 pm-2:22 pm

Nonstop1h 12m

Roanoke

Mon 12/29

6:00 am-7:34 am

Nonstop1h 34m

$405

ColumbiaRoanoke

CAE - ROA

CAEROA

Columbia Metropolitan

Wed 3/11

7:39 pm-10:13 am

2 stops14h 34m

Roanoke

Sat 3/14

7:50 pm-11:44 pm

1 stop3h 54m

$418

CharlotteRoanoke

CLT - ROA

CLTROA

Charlotte Douglas

Thu 12/25

10:00 am-2:16 pm

1 stop4h 16m

Roanoke

Mon 12/29

7:55 pm-11:59 pm

1 stop4h 04m

$425

CharlotteRoanoke

CLT - ROA

CLTROA

Charlotte Douglas

Thu 1/1

7:44 pm-11:30 pm

1 stop3h 46m

Roanoke

Sat 1/3

2:55 pm-6:55 pm

1 stop4h 00m

$425

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/10

Showing 1-10 of 28 results
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Best time to book a flight from South Carolina to Roanoke

Have a flexible travel schedule? Discover the best time to fly to Roanoke from South Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to Roanoke

What is the cheapest time of day to fly from SC to ROA?

Find hourly flight availability from South Carolina to Roanoke. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 12, 2025.

Unlike at noon, when flights are generally more expensive, you can save up to 42% on flights from South Carolina to Roanoke by exploring options for tickets in the evening.

Related info for your journey

Find useful and relevant information for your journey from South Carolina to Roanoke. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Roanoke from South Carolina?

    Most people fly into Roanoke (ROA) if they book a flight to Roanoke from South Carolina. Roanoke is conveniently located just 4.2 mi from Roanoke’s city center.

  • How long is the flight from South Carolina to Roanoke?

    Departing from South Carolina to Roanoke will take you 3h 32m. South Carolina and Roanoke are separated by a distance of 306 mi. This flight may include one or multiple stops.

  • What are the most popular routes from South Carolina to Roanoke?

    While some choose either Charlotte Douglas - Roanoke or Columbia Metropolitan - Roanoke, Charleston - Roanoke is the most popular route from South Carolina to Roanoke.

  • Can I find deals for flights from South Carolina to Roanoke that include hotel bookings?

    Yes. In addition to deals on South Carolina to Roanoke flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to Roanoke?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Roanoke.

  • Can I find deals for business class flights from South Carolina to Roanoke?

    Yes. Cheapflights offers flight deals from South Carolina to Roanoke by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near Roanoke?

Book flights to Roanoke if you plan to visit one of these locations
Radford
Salem
Blacksburg
Christiansburg

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Alternative routes for South Carolina to Roanoke

See prices for flight routes from nearby airports that may be better suited for you.
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Top airline flying from South Carolina to Roanoke

Discover the top airline that operate flights from South Carolina to Roanoke. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 12, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$218Average$320FlexibilityNo cancel feeOn-time71%

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