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Roanoke

$188+ Cheap flights from South Carolina to Roanoke (ROA)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/11. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — ROA
Jan 15 — Jan 221
Thu 1/15
Thu 1/22
1 adult, Economy
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Cheap flight deals from South Carolina to Roanoke

Cheapest flights from South Carolina to Roanoke
Explore the most affordable flight options available from South Carolina to Roanoke. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 16, 2025.

This American Airlines deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/295:10 amCHS - ROA
1 stop5h 21mAmerican Airlines
Fri 1/25:00 amROA - CHS
1 stop3h 35mAmerican Airlines
Deal found 12/14$279
This American Airlines deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/208:08 pmCHS - ROA
1 stop3h 31mAmerican Airlines
Fri 1/26:00 amROA - CHS
1 stop6h 21mAmerican Airlines
Deal found 12/14$309
This United Airlines deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/3111:40 amCHS - ROA
1 stop5h 30mUnited Airlines
Sun 1/410:32 amROA - CHS
1 stop4h 50mUnited Airlines
Deal found 12/16$319
This United Airlines deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/3010:40 amCAE - ROA
1 stop3h 36mUnited Airlines
Sat 1/36:15 amROA - CAE
1 stop3h 50mUnited Airlines
Deal found 12/15$350
This United Airlines deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/2911:40 amCHS - ROA
1 stop5h 21mUnited Airlines
Fri 1/26:40 amROA - CHS
1 stop7h 29mUnited Airlines
Deal found 12/14$389
This American Airlines deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/254:20 pmCLT - ROA
Nonstop1h 12mAmerican Airlines
Mon 12/296:00 amROA - CLT
Nonstop1h 34mAmerican Airlines
Deal found 12/15$405
This American Airlines deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/209:15 pmCLT - ROA
Nonstop1h 15mAmerican Airlines
Tue 12/2310:57 amROA - CLT
Nonstop1h 28mAmerican Airlines
Deal found 12/14$413
This United Airlines deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/257:44 pmCLT - ROA
1 stop3h 46mUnited Airlines
Mon 12/292:55 pmROA - CLT
1 stop4h 00mUnited Airlines
Deal found 12/15$425
This United Airlines deal was found by Cheapflights users on 12/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/197:37 pmCAE - ROA
1 stop3h 53mUnited Airlines
Sat 12/206:15 amROA - CAE
1 stop3h 50mUnited Airlines
Deal found 12/13$428
This United Airlines deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/202:54 pmCLT - ROA
1 stop3h 57mUnited Airlines
Tue 12/2310:32 amROA - CLT
1 stop3h 41mUnited Airlines
Deal found 12/14$433
This American Airlines deal was found by Cheapflights users on 12/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/242:35 pmCAE - ROA
1 stop4h 46mAmerican Airlines
Sat 12/272:47 pmROA - CAE
1 stop4h 46mAmerican Airlines
Deal found 12/13$433
This Delta deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/244:04 pmCHS - ROA
1 stop3h 22mDelta
Sun 12/287:03 pmROA - CHS
1 stop4h 55mDelta
Deal found 12/14$453

Find flight deals from South Carolina to Roanoke

Keep the following information in mind while searching for South Carolina to Roanoke flight deals. Data was last updated December 16, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$193
(Delta)

One-way from

$188
(Kiwi.com)
Provider with most accurate pricing for Myrtle Beach Intl-Roanoke flight deals.
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Provider most trusted by Cheapflights users for Myrtle Beach Intl-Roanoke flights.
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From South Carolina to Roanoke
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One-way flight from South Carolina to Roanoke
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Cheapflights Fare Finder

 
Customize your flight search to find flights from South Carolina to Roanoke that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 16, 2025.
Use the filters below to find and compare flights from South Carolina to Roanoke that are best for you.

Fly from

South Carolina

Fly to

Roanoke

Route

Depart

Return

Price

CharlestonRoanoke

CHS - ROA

CHSROA

Charleston

Sat 1/24

9:00 am-3:07 pm

1 stop6h 07m

Roanoke

Wed 1/28

6:00 am-11:48 am

1 stop5h 48m

$193

CharlestonRoanoke

CHS - ROA

CHSROA

Charleston

Sat 1/24

2:06 pm-8:31 pm

2 stops6h 25m

Roanoke

Wed 1/28

8:00 am-3:27 pm

1 stop7h 27m

$251

SavannahRoanoke

SAV - ROA

SAVROA

Savannah/Hilton Head

Sat 1/31

9:45 am-2:09 pm

1 stop4h 24m

Roanoke

Tue 2/3

2:55 pm-7:25 pm

1 stop4h 30m

$253

CharlestonRoanoke

CHS - ROA

CHSROA

Charleston

Mon 12/29

5:10 am-10:31 am

1 stop5h 21m

Roanoke

Fri 1/2

5:00 am-8:35 am

1 stop3h 35m

$279

CharlestonRoanoke

CHS - ROA

CHSROA

Charleston

Sat 2/7

10:30 am-5:03 pm

1 stop6h 33m

Roanoke

Tue 2/10

6:45 am-2:02 pm

1 stop7h 17m

$281

CharlestonRoanoke

CHS - ROA

CHSROA

Charleston

Thu 5/7

6:00 am-9:48 am

1 stop3h 48m

Roanoke

Fri 5/29

6:20 am-9:55 am

1 stop3h 35m

$298

ColumbiaRoanoke

CAE - ROA

CAEROA

Columbia Metropolitan

Wed 1/28

8:00 am-2:46 pm

1 stop6h 46m

Roanoke

Sat 1/31

2:55 pm-6:55 pm

1 stop4h 00m

$299

CharlestonRoanoke

CHS - ROA

CHSROA

Charleston

Thu 1/1

10:00 am-2:16 pm

1 stop4h 16m

Roanoke

Thu 1/8

12:40 pm-8:02 pm

1 stop7h 22m

$314

CharlestonRoanoke

CHS - ROA

CHSROA

Charleston

Wed 12/31

11:40 am-5:10 pm

1 stop5h 30m

Roanoke

Sun 1/4

10:32 am-3:22 pm

1 stop4h 50m

$319

ColumbiaRoanoke

CAE - ROA

CAEROA

Columbia Metropolitan

Tue 12/30

10:40 am-2:16 pm

1 stop3h 36m

Roanoke

Sat 1/3

6:15 am-10:05 am

1 stop3h 50m

$350

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/14

Showing 1-10 of 24 results
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Best time to book a flight from South Carolina to Roanoke

Have a flexible travel schedule? Discover the best time to fly to Roanoke from South Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to Roanoke

What is the cheapest time of day to fly from SC to ROA?

Find hourly flight availability from South Carolina to Roanoke. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 16, 2025.

Unlike at noon, when flights are generally more expensive, you can save up to 42% on flights from South Carolina to Roanoke by exploring options for tickets in the evening.

Related info for your journey

Find useful and relevant information for your journey from South Carolina to Roanoke. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Roanoke from South Carolina?

    Most people fly into Roanoke (ROA) if they book a flight to Roanoke from South Carolina. Roanoke is conveniently located just 4.2 mi from Roanoke’s city center.

  • How long is the flight from South Carolina to Roanoke?

    Departing from South Carolina to Roanoke will take you 4h 24m. South Carolina and Roanoke are separated by a distance of 366 mi. This flight may include one or multiple stops.

  • What are the most popular routes from South Carolina to Roanoke?

    While some choose either Charleston - Roanoke or Savannah/Hilton Head - Roanoke, Charlotte Douglas - Roanoke is the most popular route from South Carolina to Roanoke.

  • Can I find deals for flights from South Carolina to Roanoke that include hotel bookings?

    Yes. In addition to deals on South Carolina to Roanoke flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to Roanoke?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Roanoke.

  • Can I find deals for business class flights from South Carolina to Roanoke?

    Yes. Cheapflights offers flight deals from South Carolina to Roanoke by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near Roanoke?

Book flights to Roanoke if you plan to visit one of these locations
Radford
Salem
Blacksburg
Christiansburg

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Alternative routes for South Carolina to Roanoke

See prices for flight routes from nearby airports that may be better suited for you.
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Top airline flying from South Carolina to Roanoke

Discover the top airline that operate flights from South Carolina to Roanoke. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 16, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$218Average$320FlexibilityNo cancel feeOn-time71%

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