$274+ Cheap flights from South Carolina to Roanoke (ROA)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/9. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — ROA
Oct 15 — Oct 221
Round-trip
1 adult, Economy
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Find cheap flights from South Carolina to Roanoke with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from South Carolina to Roanoke
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Cheapest flights from South Carolina to RoanokeExplore the most affordable flight options available from South Carolina to Roanoke. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 15, 2026.
Explore the most affordable flight options available from South Carolina to Roanoke. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 15, 2026.
This Delta deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/205:30 am -
1 stop5h 02m
Wed 10/286:00 am -
1 stop4h 10m
Deal found 9/14![Delta logo]()
$291
This Delta deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/237:05 pm -
1 stop5h 22m
Wed 10/286:00 am -
1 stop5h 35m
Deal found 9/14![Delta logo]()
$305
This Delta deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/105:11 pm -
1 stop4h 46m
Fri 10/166:00 am -
1 stop3h 30m
Deal found 9/11![Delta logo]()
$309
This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/86:00 am -
1 stop3h 48m
Mon 10/126:15 am -
1 stop3h 47m
Deal found 9/15![United Airlines logo]()
$319
This United Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/307:30 pm -
1 stop4h 14m
Sun 11/16:00 am -
1 stop5h 00m
Deal found 9/14![United Airlines logo]()
$319
This Delta deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/168:09 pm -
1 stop4h 18m
Fri 10/236:38 pm -
1 stop4h 02m
Deal found 9/14![Delta logo]()
$339
This Delta deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/225:30 am -
1 stop5h 02m
Wed 10/286:00 am -
1 stop4h 10m
Deal found 9/14![Delta logo]()
$340
This American Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/238:04 am -
1 stop5h 22m
Sun 9/275:06 am -
1 stop3h 27m
Deal found 9/11![American Airlines logo]()
$343
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/2910:27 am -
1 stop6h 14m
Sat 10/311:15 am -
1 stop5h 35m
Deal found 9/14![American Airlines logo]()
$349
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/255:32 pm -
1 stop3h 27m
Tue 9/2912:11 pm -
1 stop4h 31m
Deal found 9/10![American Airlines logo]()
$349
This Delta deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/225:30 am -
1 stop5h 02m
Sun 10/256:00 am -
1 stop5h 35m
Deal found 9/14![Delta logo]()
$354
This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1910:23 am -
1 stop3h 52m
Mon 11/236:00 am -
1 stop4h 06m
Deal found 9/10![United Airlines logo]()
$369
Best flights from South Carolina to RoanokeDiscover carefully curated flight deals from South Carolina to Roanoke that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 15, 2026.
Discover carefully curated flight deals from South Carolina to Roanoke that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 15, 2026.
This Delta deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/105:11 pm -
1 stop4h 46m
Fri 10/166:00 am -
1 stop3h 30m
Deal found 9/11![Delta logo]()
$309
This United Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/166:00 am -
1 stop3h 48m
Sun 10/186:15 am -
1 stop3h 47m
Deal found 9/13![United Airlines logo]()
$354
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/1911:18 am -
1 stop5h 27m
Mon 9/213:27 pm -
1 stop5h 39m
Deal found 9/14![American Airlines logo]()
$376
This Delta deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/168:09 pm -
1 stop4h 18m
Fri 10/236:38 pm -
1 stop4h 02m
Deal found 9/14![Delta logo]()
$339
This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1910:23 am -
1 stop3h 52m
Mon 11/236:00 am -
1 stop4h 06m
Deal found 9/10![United Airlines logo]()
$369
This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/2612:15 pm -
1 stop8h 50m
Sat 1/303:00 pm -
1 stop4h 12m
Deal found 9/10![United Airlines logo]()
$369
This United Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/65:33 pm -
1 stop6h 59m
Wed 2/1010:20 am -
1 stop3h 56m
Deal found 9/14![United Airlines logo]()
$379
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/299:35 am -
2 stops7h 10m
Sat 10/31:57 pm -
1 stop5h 07m
Deal found 9/14![American Airlines logo]()
$470
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/305:40 am -
1 stop4h 51m
Sun 10/46:00 am -
1 stop3h 25m
Deal found 9/15![Delta logo]()
$474
This United Airlines deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/177:50 pm -
1 stop3h 54m
Sat 10/248:05 pm -
1 stop3h 51m
Deal found 9/12![United Airlines logo]()
$449
This United Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/293:01 pm -
1 stop4h 06m
Sat 10/38:05 pm -
1 stop3h 51m
Deal found 9/14![United Airlines logo]()
$503
This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/65:33 pm -
1 stop6h 59m
Mon 2/83:00 pm -
1 stop23h 16m
Deal found 9/10![United Airlines logo]()
$518
This United Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/61:00 pm -
1 stop8h 05m
Tue 2/93:00 pm -
1 stop3h 41m
Deal found 9/11![United Airlines logo]()
$519
This United Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/175:31 pm -
1 stop5h 28m
Mon 10/196:15 am -
1 stop3h 29m
Deal found 9/14![United Airlines logo]()
$546
This United Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/23:04 pm -
1 stop7h 55m
Sun 10/48:05 pm -
1 stop3h 54m
Deal found 9/11![United Airlines logo]()
$555
This United Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/86:00 am -
1 stop3h 48m
Tue 10/138:05 pm -
2 stops17h 50m
Deal found 9/14![United Airlines logo]()
$583
This United Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/307:30 pm -
1 stop4h 14m
Sun 11/16:30 am -
3 stops17h 00m
Deal found 9/14![United Airlines logo]()
$599
This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/257:53 pm -
1 stop3h 51m
Tue 9/298:05 pm -
3 stops17h 59m
Deal found 9/10![United Airlines logo]()
$617
Last-minute flights from South Carolina to RoanokeDiscover last-minute flight deals from South Carolina to Roanoke. Data last updated September 15, 2026 and is based on user searches.
Discover last-minute flight deals from South Carolina to Roanoke. Data last updated September 15, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/238:04 am -
1 stop5h 22m
Sun 9/275:06 am -
1 stop3h 27m
Deal found 9/11![American Airlines logo]()
$343
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/255:32 pm -
1 stop3h 27m
Tue 9/2912:11 pm -
1 stop4h 31m
Deal found 9/10![American Airlines logo]()
$349
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/2910:27 am -
1 stop6h 14m
Sat 10/311:15 am -
1 stop5h 35m
Deal found 9/14![American Airlines logo]()
$349
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/299:35 am -
1 stop5h 26m
Sat 10/312:11 pm -
1 stop4h 31m
Deal found 9/14![American Airlines logo]()
$369
This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/86:00 am -
1 stop3h 48m
Mon 10/126:15 am -
1 stop3h 47m
Deal found 9/15![United Airlines logo]()
$319
This Delta deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/105:11 pm -
1 stop4h 46m
Fri 10/166:00 am -
1 stop3h 30m
Deal found 9/11![Delta logo]()
$309
This Delta deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/168:09 pm -
1 stop4h 18m
Fri 10/236:38 pm -
1 stop4h 02m
Deal found 9/14![Delta logo]()
$339
This Delta deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/205:43 pm -
1 stop6h 44m
Sat 10/246:00 am -
1 stop5h 04m
Deal found 9/14![Delta logo]()
$291
This Delta deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/225:30 am -
1 stop5h 02m
Wed 10/286:00 am -
1 stop4h 10m
Deal found 9/14![Delta logo]()
$340
This Delta deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/225:30 am -
1 stop5h 02m
Sun 10/256:00 am -
1 stop5h 35m
Deal found 9/14![Delta logo]()
$354
This Delta deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/237:05 pm -
1 stop5h 22m
Wed 10/286:00 am -
1 stop5h 35m
Deal found 9/14![Delta logo]()
$305
This United Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/307:30 pm -
1 stop4h 14m
Sun 11/16:00 am -
1 stop5h 00m
Deal found 9/14![United Airlines logo]()
$319
One-way flights from South Carolina to RoanokeSearch for one-way flight options from South Carolina to Roanoke. Find affordable one-way fares based on user searches. Data last updated September 15, 2026.
Search for one-way flight options from South Carolina to Roanoke. Find affordable one-way fares based on user searches. Data last updated September 15, 2026.
This United Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/96:00 am -
1 stop3h 48m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/14![United Airlines logo]()
$274
This Kiwi.com deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/119:32 am -
3 stops28h 50m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/12![Multiple Airlines logo]()
$285
This American Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/27:45 pm -
Nonstop1h 14m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/11![American Airlines logo]()
$300
This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/247:15 am -
3 stops25h 07m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/10![Multiple Airlines logo]()
$300
This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/129:39 pm -
3 stops22h 21m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/15![Multiple Airlines logo]()
$305
This United Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/25:31 pm -
1 stop5h 28m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/11![United Airlines logo]()
$310
This Kiwi.com deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/910:00 am -
3 stops34h 00m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/11![Multiple Airlines logo]()
$320
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/244:15 pm -
1 stop4h 44m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/10![American Airlines logo]()
$323
This United Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/147:55 pm -
1 stop13h 56m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/14![United Airlines logo]()
$330
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/15:25 am -
1 stop5h 06m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/15![Delta logo]()
$333
This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/17:00 am -
2 stops32h 09m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/15![Multiple Airlines logo]()
$348
This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/205:45 am -
1 stop4h 02m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/10![United Airlines logo]()
$374
Find flight deals from South Carolina to Roanoke
Keep the following information in mind while searching for South Carolina to Roanoke flight deals. Data was last updated September 15, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $291 (Delta) |
One-way from | $274 (United Airlines) |
Cheapflights Fare Finder
Customize your flight search to find flights from South Carolina to Roanoke that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 15, 2026.
Use the filters below to find and compare flights from South Carolina to Roanoke that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
CharlestonRoanoke
CHS Charleston - ROA Roanoke
CHSROA
Charleston
Fri 10/9
6:00 am-9:48 am
1 stop3h 48m
Roanoke
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$274
ColumbiaRoanoke
CAE Columbia Metropolitan - ROA Roanoke
CAEROA
Columbia Metropolitan
Sat 10/10
5:11 pm-9:57 pm
1 stop4h 46m
Roanoke
Fri 10/16
6:00 am-9:30 am
1 stop3h 30m
$309
CharlotteRoanoke
CLT Charlotte Douglas - ROA Roanoke
CLTROA
Charlotte Douglas
Sat 11/14
7:55 pm-9:51 am
1 stop13h 56m
Roanoke
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$330
CharlestonRoanoke
CHS Charleston - ROA Roanoke
CHSROA
Charleston
Thu 10/1
5:25 am-10:31 am
1 stop5h 06m
Roanoke
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$333
CharlestonRoanoke
CHS Charleston - ROA Roanoke
CHSROA
Charleston
Fri 10/2
6:52 pm-11:59 pm
1 stop5h 07m
Roanoke
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$333
Quickest round-trip
CharlestonRoanoke
CHS Charleston - ROA Roanoke
CHSROA
Charleston
Sat 10/3
7:00 am-10:31 am
1 stop3h 31m
Roanoke
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$333
SavannahRoanoke
SAV Savannah/Hilton Head - ROA Roanoke
SAVROA
Savannah/Hilton Head
Fri 10/16
8:09 pm-12:27 am
1 stop4h 18m
Roanoke
Fri 10/23
6:38 pm-10:40 pm
1 stop4h 02m
$339
CharlestonRoanoke
CHS Charleston - ROA Roanoke
CHSROA
Charleston
Thu 10/1
7:00 am-3:09 pm
2 stops32h 09m
Roanoke
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$348
CharlotteRoanoke
CLT Charlotte Douglas - ROA Roanoke
CLTROA
Charlotte Douglas
Fri 12/11
5:17 pm-3:34 pm
1 stop22h 17m
Roanoke
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$354
CharlestonRoanoke
CHS Charleston - ROA Roanoke
CHSROA
Charleston
Fri 10/16
6:00 am-9:48 am
1 stop3h 48m
Roanoke
Sun 10/18
6:15 am-10:02 am
1 stop3h 47m
$354
Showing 1-10 of 36 resultsSorted by cheapest first
Best time to book a flight from South Carolina to Roanoke
Have a flexible travel schedule? Discover the best time to fly to Roanoke from South Carolina with our price prediction graph.
CHS-ROA
CLT-ROA
SAV-ROA
CAE-ROA
Estimated round-trip price
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Cheapflights Insights
Everything you need to know about your flight from South Carolina to Roanoke
USSC-ROA
CHS-ROA
CLT-ROA
SAV-ROA
CAE-ROA
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Related info for your journey
Find useful and relevant information for your journey from South Carolina to Roanoke. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Roanoke?
Book flights to Roanoke if you plan to visit one of these locationsSalem
Radford
Blacksburg
Christiansburg
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South Carolina and Roanoke flights
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Other flights to Roanoke
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South Carolina to Roanoke flights
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Top 2 airlines flying from South Carolina to Roanoke
Discover the top 2 airlines that operate flights from South Carolina to Roanoke. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 15, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$278 | Average$308 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$278 | Average$278 | FlexibilityNo cancel fee | On-timeN/A |