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Roanoke

$170+ Cheap flights from South Carolina to Roanoke (ROA)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/28. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — ROA
Feb 28 — Mar 71
Sat 2/28
Sat 3/7
1 adult, Economy
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Cheap flight deals from South Carolina to Roanoke

Cheapest flights from South Carolina to Roanoke
Explore the most affordable flight options available from South Carolina to Roanoke. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 29, 2026.

This Delta deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/115:30 pm
CHS
-
ROA
1 stop6h 34m
Delta
Sun 2/156:00 am
ROA
-
CHS
1 stop5h 56m
Delta
Deal found 1/27$259
This Delta deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/116:50 am
SAV
-
ROA
1 stop3h 49m
Delta
Sun 2/157:59 pm
ROA
-
SAV
1 stop3h 58m
Delta
Deal found 1/27$259
This American Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/111:18 pm
SAV
-
ROA
2 stops7h 13m
American Airlines
Sun 2/158:00 pm
ROA
-
SAV
1 stop3h 57m
American Airlines
Deal found 1/27$264
This United Airlines deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/710:18 am
CAE
-
ROA
1 stop3h 40m
United Airlines
Tue 11/1010:20 am
ROA
-
CAE
1 stop3h 50m
United Airlines
Deal found 1/28$304
This United Airlines deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/710:30 am
CHS
-
ROA
1 stop6h 33m
United Airlines
Tue 2/1010:15 am
ROA
-
CHS
1 stop4h 33m
United Airlines
Deal found 1/26$339
This United Airlines deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/1710:23 am
CLT
-
ROA
1 stop3h 35m
United Airlines
Tue 10/2011:00 am
ROA
-
CLT
1 stop6h 07m
United Airlines
Deal found 1/28$359
This United Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/319:45 am
SAV
-
ROA
1 stop4h 24m
United Airlines
Tue 2/33:39 pm
ROA
-
SAV
1 stop5h 57m
United Airlines
Deal found 1/27$369
This American Airlines deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/268:59 pm
CLT
-
ROA
Nonstop1h 25m
American Airlines
Mon 3/305:00 am
ROA
-
CLT
Nonstop1h 21m
American Airlines
Deal found 1/28$379
This United Airlines deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/269:40 am
CLT
-
ROA
1 stop4h 29m
United Airlines
Mon 3/3010:34 am
ROA
-
CLT
1 stop3h 31m
United Airlines
Deal found 1/28$399
This American Airlines deal was found by Cheapflights users on 1/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/2710:25 pm
CLT
-
ROA
Nonstop1h 20m
American Airlines
Sun 3/296:00 am
ROA
-
CLT
Nonstop1h 33m
American Airlines
Deal found 1/29$412
This United Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/117:19 pm
SAV
-
ROA
1 stop18h 53m
United Airlines
Sun 2/1510:15 am
ROA
-
SAV
1 stop4h 32m
United Airlines
Deal found 1/27$413
This American Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/114:07 pm
CHS
-
ROA
1 stop4h 24m
American Airlines
Sun 2/158:15 am
ROA
-
CHS
2 stops7h 42m
American Airlines
Deal found 1/27$437

Find flight deals from South Carolina to Roanoke

Keep the following information in mind while searching for South Carolina to Roanoke flight deals. Data was last updated January 29, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$259
(Delta)

One-way from

$170
(Kiwi.com)
Provider with most accurate pricing for Myrtle Beach Intl-Roanoke flight deals.
Search Deals
Provider most trusted by Cheapflights users for Myrtle Beach Intl-Roanoke flights.
Search Deals
From South Carolina to Roanoke
Search Deals
One-way flight from South Carolina to Roanoke
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Cheapflights Fare Finder

 
Customize your flight search to find flights from South Carolina to Roanoke that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 29, 2026.
Use the filters below to find and compare flights from South Carolina to Roanoke that are best for you.

Fly from

South Carolina

Fly to

Roanoke

Route

Depart

Return

Price

CharlestonRoanoke

CHS - ROA

CHSROA

Charleston

Wed 2/11

5:30 pm-12:04 am

1 stop6h 34m

Roanoke

Sun 2/15

6:00 am-11:56 am

1 stop5h 56m

$259

SavannahRoanoke

SAV - ROA

SAVROA

Savannah/Hilton Head

Wed 2/11

6:50 am-10:39 am

1 stop3h 49m

Roanoke

Sun 2/15

7:59 pm-11:57 pm

1 stop3h 58m

$259

SavannahRoanoke

SAV - ROA

SAVROA

Savannah/Hilton Head

Wed 2/11

1:18 pm-8:31 pm

2 stops7h 13m

Roanoke

Sun 2/15

8:15 am-2:28 pm

2 stops6h 13m

$343

CharlotteRoanoke

CLT - ROA

CLTROA

Charlotte Douglas

Thu 3/26

8:59 pm-10:24 pm

Nonstop1h 25m

Roanoke

Mon 3/30

5:00 am-6:21 am

Nonstop1h 21m

$379

CharlotteRoanoke

CLT - ROA

CLTROA

Charlotte Douglas

Thu 3/26

9:40 am-2:09 pm

1 stop4h 29m

Roanoke

Mon 3/30

10:34 am-2:05 pm

1 stop3h 31m

$399

CharlotteRoanoke

CLT - ROA

CLTROA

Charlotte Douglas

Fri 3/27

10:25 pm-11:45 pm

Nonstop1h 20m

Roanoke

Sun 3/29

6:00 am-7:33 am

Nonstop1h 33m

$412

SavannahRoanoke

SAV - ROA

SAVROA

Savannah/Hilton Head

Wed 2/11

7:19 pm-2:12 pm

1 stop18h 53m

Roanoke

Sun 2/15

10:15 am-2:47 pm

1 stop4h 32m

$413

CharlestonRoanoke

CHS - ROA

CHSROA

Charleston

Wed 2/11

4:07 pm-8:31 pm

1 stop4h 24m

Roanoke

Sun 2/15

8:15 am-3:57 pm

2 stops7h 42m

$437

CharlotteRoanoke

CLT - ROA

CLTROA

Charlotte Douglas

Fri 2/20

7:44 pm-8:07 pm

1 stop24h 23m

Roanoke

Sun 2/22

10:15 am-2:11 pm

1 stop3h 56m

$441

CharlotteRoanoke

CLT - ROA

CLTROA

Charlotte Douglas

Fri 2/20

9:08 am-10:37 am

Nonstop1h 29m

Roanoke

Sun 2/22

5:00 am-6:21 am

Nonstop1h 21m

$445

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/27

Showing 1-10 of 29 results
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Best time to book a flight from South Carolina to Roanoke

Have a flexible travel schedule? Discover the best time to fly to Roanoke from South Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to Roanoke
No data available for this route at this time. Please check back soon.

Related info for your journey

Find useful and relevant information for your journey from South Carolina to Roanoke. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Roanoke from South Carolina?

    Most people fly into Roanoke (ROA) if they book a flight to Roanoke from South Carolina. Roanoke is conveniently located just 4.2 mi from Roanoke’s city center.

  • How long is the flight from South Carolina to Roanoke?

    Departing from South Carolina to Roanoke will take you 4h 29m. South Carolina and Roanoke are separated by a distance of 155 mi. This flight may include one or multiple stops.

  • What are the most popular routes from South Carolina to Roanoke?

    While some choose either Charlotte Douglas - Roanoke or Savannah/Hilton Head - Roanoke, Charleston - Roanoke is the most popular route from South Carolina to Roanoke.

  • Can I find deals for flights from South Carolina to Roanoke that include hotel bookings?

    Yes. In addition to deals on South Carolina to Roanoke flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to Roanoke?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Roanoke.

  • Can I find deals for business class flights from South Carolina to Roanoke?

    Yes. Cheapflights offers flight deals from South Carolina to Roanoke by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near Roanoke?

Book flights to Roanoke if you plan to visit one of these locations
Salem
Radford
Blacksburg
Christiansburg

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Alternative routes for South Carolina to Roanoke

See prices for flight routes from nearby airports that may be better suited for you.
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Top airline flying from South Carolina to Roanoke

Discover the top airline that operate flights from South Carolina to Roanoke. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 29, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$218Average$320FlexibilityNo cancel feeOn-time71%

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