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South Carolina

$204+ Cheap flights from Roanoke (ROA) to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/14. Fares are subject to change and may not be available on all flights or dates of travel.
ROA — CHS
Jul 18 — Jul 251
Sat 7/18
Sat 7/25
1 adult, Economy
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Cheap flight deals from Roanoke to South Carolina

Cheapest flights from Roanoke to South Carolina
Explore the most affordable flight options available from Roanoke to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 18, 2026.

This Delta deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/37:59 pm
ROA
-
CHS
1 stop4h 37m
Delta
Fri 7/107:59 pm
CHS
-
ROA
1 stop4h 26m
Delta
Deal found 6/15$275
This American Airlines deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/85:00 am
ROA
-
CHS
1 stop3h 23m
American Airlines
Tue 7/141:00 pm
CHS
-
ROA
1 stop3h 14m
American Airlines
Deal found 6/15$289
This Delta deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/167:57 pm
ROA
-
MYR
1 stop3h 58m
Delta
Thu 7/237:59 pm
MYR
-
ROA
1 stop4h 26m
Delta
Deal found 6/15$291
This American Airlines deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/294:42 pm
ROA
-
CHS
1 stop5h 23m
American Airlines
Sat 7/45:00 am
CHS
-
ROA
1 stop5h 40m
American Airlines
Deal found 6/13$304
This Delta deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/246:00 am
ROA
-
MYR
1 stop4h 47m
Delta
Sat 8/296:00 am
MYR
-
ROA
1 stop4h 37m
Delta
Deal found 6/17$311
This United Airlines deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/196:40 am
ROA
-
CHS
1 stop7h 18m
United Airlines
Tue 9/227:51 pm
CHS
-
ROA
1 stop3h 52m
United Airlines
Deal found 6/15$331
This American Airlines deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/1611:10 am
ROA
-
CHS
1 stop3h 31m
American Airlines
Tue 6/2312:58 pm
CHS
-
ROA
1 stop3h 14m
American Airlines
Deal found 6/15$347
This United Airlines deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/57:00 am
ROA
-
MYR
1 stop7h 33m
United Airlines
Tue 12/83:20 pm
MYR
-
ROA
1 stop5h 19m
United Airlines
Deal found 6/15$349
This Delta deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/187:59 pm
ROA
-
MYR
1 stop4h 00m
Delta
Mon 6/221:54 pm
MYR
-
ROA
1 stop5h 23m
Delta
Deal found 6/14$354
This Delta deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/93:28 pm
ROA
-
MYR
1 stop3h 39m
Delta
Wed 7/156:00 am
MYR
-
ROA
1 stop4h 30m
Delta
Deal found 6/14$355
This American Airlines deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/254:42 pm
ROA
-
CHS
1 stop5h 23m
American Airlines
Mon 6/296:51 am
CHS
-
ROA
1 stop3h 54m
American Airlines
Deal found 6/17$359
This American Airlines deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/206:02 pm
ROA
-
CHS
1 stop4h 09m
American Airlines
Mon 6/2210:52 am
CHS
-
ROA
1 stop5h 20m
American Airlines
Deal found 6/16$363

Find flight deals from Roanoke to South Carolina

Keep the following information in mind while searching for Roanoke to South Carolina flight deals. Data was last updated June 18, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$275
(Delta)

One-way from

$204
(Kiwi.com)

Popular in

August

Cheapest in

January

Average price

$491
Provider with most accurate pricing for Roanoke-Myrtle Beach Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Roanoke-Myrtle Beach Intl flights.
Search Deals
From Roanoke to South Carolina
Search Deals
One-way flight from Roanoke to South Carolina
Search Deals
Highest demand for flights based on searches. 21% potential increase in price ($109 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 4% potential price decrease ($16 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in June 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Roanoke to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 18, 2026.
Use the filters below to find and compare flights from Roanoke to South Carolina that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

RoanokeCharleston

ROA - CHS

ROACHS

Roanoke

Fri 7/3

7:53 pm-11:59 pm

1 stop4h 06m

Charleston

Sat 7/11

7:50 pm-11:59 pm

1 stop4h 09m

$275

RoanokeCharleston

ROA - CHS

ROACHS

Roanoke

Sat 9/19

6:40 am-1:58 pm

1 stop7h 18m

Charleston

Tue 9/22

7:51 pm-11:43 pm

1 stop3h 52m

$331

RoanokeCharleston

ROA - CHS

ROACHS

Roanoke

Mon 6/29

4:42 pm-10:05 pm

1 stop5h 23m

Charleston

Sat 7/4

5:00 am-10:40 am

1 stop5h 40m

$339

RoanokeMyrtle Beach

ROA - MYR

ROAMYR

Roanoke

Sat 10/3

6:49 am-3:16 pm

1 stop8h 27m

Myrtle Beach Intl

Tue 10/6

10:23 am-2:19 pm

1 stop3h 56m

$349

RoanokeMyrtle Beach

ROA - MYR

ROAMYR

Roanoke

Sat 12/5

7:00 am-2:33 pm

1 stop7h 33m

Myrtle Beach Intl

Tue 12/8

3:20 pm-8:39 pm

1 stop5h 19m

$349

RoanokeMyrtle Beach

ROA - MYR

ROAMYR

Roanoke

Thu 7/16

7:57 pm-11:55 pm

1 stop3h 58m

Myrtle Beach Intl

Thu 7/23

7:59 pm-12:25 am

1 stop4h 26m

$355

RoanokeMyrtle Beach

ROA - MYR

ROAMYR

Roanoke

Fri 8/28

11:18 am-6:07 pm

1 stop6h 49m

Myrtle Beach Intl

Sat 8/29

6:00 am-10:37 am

1 stop4h 37m

$375

RoanokeCharleston

ROA - CHS

ROACHS

Roanoke

Sun 7/12

7:57 pm-12:26 am

1 stop4h 29m

Charleston

Sun 7/19

7:59 pm-12:25 am

1 stop4h 26m

$412

RoanokeCharlotte

ROA - CLT

ROACLT

Roanoke

Wed 7/15

6:15 am-9:45 am

1 stop3h 30m

Charlotte Douglas

Tue 7/21

6:00 am-9:42 am

1 stop3h 42m

$426

RoanokeCharleston

ROA - CHS

ROACHS

Roanoke

Thu 7/2

4:49 pm-10:03 pm

1 stop5h 14m

Charleston

Sun 7/5

5:00 am-10:40 am

1 stop5h 40m

$447

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/13

Showing 1-10 of 57 resultsSorted by cheapest first
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2
3
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6

Best time to book a flight from Roanoke to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Roanoke with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Roanoke to South Carolina

What is the cheapest month to book a flight from Roanoke to South Carolina?

Currently, January is the cheapest month in which you can book a flight from Roanoke to South Carolina (average of $144). Flying from Roanoke to South Carolina in December is currently the most expensive (average of $368). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Roanoke to South Carolina?

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated June 18, 2026.
Read through reviews of airlines operating flights from Roanoke to South Carolina, such as American Airlines. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.1
Good
11,686 reviews

Overall

7.1

Food

6.4

Comfort

7.2

Boarding

7.5

Crew

7.9

Entertainment

6.8

Reviews

1 / 20
2.0
Mediocre

Anonymous,Apr 2026

DFW - BDL

They keep changing the gate, delaying the hours and then finally canceled it. No accomodation, no food, nothing!
American Airlines
7.1
Good
11,686 reviews
American Airlines
7.1
Good
11,686 reviews

Overall

7.1

Food

6.4

Comfort

7.2

Boarding

7.5

Crew

7.9

Entertainment

6.8

Reviews

1 / 20
2.0
Mediocre

Anonymous,Apr 2026

DFW - BDL

They keep changing the gate, delaying the hours and then finally canceled it. No accomodation, no food, nothing!

Related info for your journey

Find useful and relevant information for your journey from Roanoke to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Roanoke to South Carolina?

    If you book a flight to South Carolina from Roanoke, you will be flying from Roanoke, which is the city’s only airport. Roanoke (ROA) is located 4.2 mi from the center of Roanoke.

  • How long is the flight from Roanoke to South Carolina?

    Delta, American Airlines, and United Airlines can get you from Roanoke to South Carolina in just under 4h 06m. Your travel time can differ by up to 3h 12m. The distance between Roanoke and South Carolina is about 306 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the most popular routes from Roanoke to South Carolina?

    When deciding which route to take from Roanoke to South Carolina consider Roanoke - Charleston, Roanoke - Myrtle Beach Intl or Roanoke - Charlotte Douglas as they are the most popular.

  • Can I find deals for flights from Roanoke to South Carolina that include hotel bookings?

    Yes. In addition to deals on Roanoke to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Roanoke to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Roanoke to South Carolina.

  • Can I find deals for business class flights from Roanoke to South Carolina?

    Yes. Cheapflights offers flight deals from Roanoke to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Roanoke to South Carolina?

    Currently, January is the cheapest month in which you can book a flight from Roanoke to South Carolina (average of $144). Flying from Roanoke to South Carolina in December is currently the most expensive (average of $368). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Roanoke to South Carolina

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Top airline flying from Roanoke to South Carolina

Discover the top airline that operate flights from Roanoke to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 18, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$218Average$477FlexibilityNo cancel feeOn-time71%

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