$179+ Cheap flights from Roanoke (ROA) to South Carolina
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/13. Fares are subject to change and may not be available on all flights or dates of travel.
ROA — CHS
Sep 4 — Sep 111
Round-trip
1 adult, Economy
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Find cheap flights from Roanoke to South Carolina with Cheapflights
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Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from Roanoke to South CarolinaExplore the most affordable flight options available from Roanoke to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 5, 2026.
Explore the most affordable flight options available from Roanoke to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 5, 2026.
This American Airlines deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/2212:11 pm -
1 stop4h 39m
Sat 9/265:31 pm -
1 stop3h 28m
Deal found 8/3![American Airlines logo]()
$271
This Delta deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/37:59 pm -
1 stop4h 00m
Sat 9/54:56 pm -
1 stop4h 42m
Deal found 8/1![Delta logo]()
$285
This United Airlines deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/36:15 am -
1 stop3h 48m
Thu 9/107:51 pm -
1 stop3h 52m
Deal found 8/1![United Airlines logo]()
$299
This Delta deal was found by Cheapflights users on 8/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/226:00 am -
1 stop4h 07m
Mon 10/56:56 pm -
1 stop5h 03m
Deal found 8/2![Delta logo]()
$311
This American Airlines deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/151:57 pm -
1 stop4h 48m
Tue 9/228:08 am -
1 stop3h 35m
Deal found 8/3![American Airlines logo]()
$313
This Delta deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/176:00 am -
1 stop5h 54m
Wed 8/266:45 pm -
1 stop5h 42m
Deal found 8/3![Delta logo]()
$314
This American Airlines deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/145:07 am -
1 stop5h 54m
Sun 10/188:12 pm -
1 stop3h 32m
Deal found 8/3![American Airlines logo]()
$322
This Delta deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/276:00 am -
1 stop4h 47m
Sun 8/307:02 pm -
1 stop5h 25m
Deal found 8/3![Delta logo]()
$327
This Delta deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/207:59 pm -
1 stop4h 00m
Sun 8/236:45 pm -
1 stop5h 42m
Deal found 8/3![Delta logo]()
$329
This Delta deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/206:00 am -
1 stop4h 08m
Sun 10/45:25 am -
1 stop5h 06m
Deal found 8/1![Delta logo]()
$334
This United Airlines deal was found by Cheapflights users on 8/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/16:40 am -
1 stop7h 18m
Sat 9/510:14 am -
1 stop4h 04m
Deal found 8/2![United Airlines logo]()
$341
This Kiwi.com deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/2010:51 am -
1 stop27h 15m
Sun 8/232:58 pm -
1 stop22h 48m
Deal found 8/4![Multiple Airlines logo]()
$343
Best flights from Roanoke to South CarolinaDiscover carefully curated flight deals from Roanoke to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 5, 2026.
Discover carefully curated flight deals from Roanoke to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 5, 2026.
This Delta deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/106:00 am -
1 stop3h 25m
Mon 10/125:30 am -
1 stop5h 02m
Deal found 8/1![Delta logo]()
$285
This United Airlines deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/110:26 am -
1 stop4h 44m
Sat 9/511:40 am -
1 stop5h 29m
Deal found 7/31![United Airlines logo]()
$341
This American Airlines deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/58:00 am -
Nonstop1h 29m
Sun 9/63:14 pm -
Nonstop1h 14m
Deal found 8/3![American Airlines logo]()
$391
This Delta deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/37:59 pm -
1 stop4h 00m
Sat 9/54:56 pm -
1 stop4h 42m
Deal found 8/1![Delta logo]()
$285
This Delta deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/104:46 pm -
1 stop4h 55m
Thu 9/176:56 pm -
1 stop5h 03m
Deal found 7/31![Delta logo]()
$311
This Delta deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/156:00 am -
1 stop4h 07m
Tue 9/226:00 am -
1 stop4h 31m
Deal found 8/1![Delta logo]()
$311
This American Airlines deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/173:27 pm -
1 stop5h 41m
Thu 9/2412:10 pm -
1 stop4h 31m
Deal found 8/3![American Airlines logo]()
$404
This Delta deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/176:32 pm -
1 stop5h 27m
Thu 9/246:52 pm -
1 stop5h 07m
Deal found 8/3![Delta logo]()
$314
This United Airlines deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/118:05 pm -
1 stop3h 54m
Fri 9/187:55 pm -
1 stop3h 48m
Deal found 8/4![United Airlines logo]()
$439
This American Airlines deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/1112:11 pm -
Nonstop1h 22m
Fri 9/1810:25 am -
Nonstop1h 18m
Deal found 8/4![American Airlines logo]()
$419
This Delta deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/276:00 am -
1 stop4h 47m
Sun 8/307:02 pm -
1 stop5h 25m
Deal found 8/3![Delta logo]()
$327
This United Airlines deal was found by Cheapflights users on 8/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/246:15 am -
1 stop3h 29m
Thu 8/2710:23 am -
1 stop3h 55m
Deal found 8/2![United Airlines logo]()
$467
This Delta deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/246:32 pm -
1 stop5h 27m
Sun 9/275:25 am -
1 stop5h 06m
Deal found 8/3![Delta logo]()
$334
This United Airlines deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/308:00 pm -
1 stop3h 59m
Sun 11/110:24 am -
1 stop3h 51m
Deal found 8/1![United Airlines logo]()
$469
This Delta deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/206:00 am -
1 stop4h 08m
Sun 10/45:25 am -
1 stop5h 06m
Deal found 8/1![Delta logo]()
$334
This American Airlines deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/275:07 pm -
1 stop5h 31m
Sat 9/126:30 am -
2 stops10h 15m
Deal found 8/4![American Airlines logo]()
$511
This United Airlines deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/58:05 pm -
1 stop3h 51m
Sun 9/63:00 pm -
1 stop4h 07m
Deal found 8/3![United Airlines logo]()
$481
This American Airlines deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/307:44 am -
1 stop6h 11m
Sun 11/17:12 am -
Nonstop1h 14m
Deal found 8/1![American Airlines logo]()
$533
This Delta deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/55:02 pm -
1 stop4h 47m
Sat 9/126:00 am -
1 stop4h 31m
Deal found 7/31![Delta logo]()
$385
This United Airlines deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/158:05 pm -
1 stop3h 51m
Wed 8/1910:25 am -
1 stop3h 54m
Deal found 7/31![United Airlines logo]()
$533
This United Airlines deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/18:05 pm -
1 stop3h 51m
Mon 9/77:55 pm -
1 stop3h 48m
Deal found 8/3![United Airlines logo]()
$536
This Delta deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/186:32 pm -
1 stop4h 56m
Sun 9/206:00 am -
1 stop4h 31m
Deal found 8/1![Delta logo]()
$425
This United Airlines deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/108:05 pm -
1 stop3h 54m
Thu 9/177:55 pm -
1 stop3h 48m
Deal found 7/31![United Airlines logo]()
$548
This United Airlines deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/2610:26 am -
2 stops10h 18m
Sat 8/296:00 am -
1 stop3h 47m
Deal found 8/3![United Airlines logo]()
$620
This Delta deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/247:04 am -
2 stops11h 03m
Sat 9/126:00 am -
1 stop4h 31m
Deal found 8/4![Delta logo]()
$522
Last-minute flights from Roanoke to South CarolinaDiscover last-minute flight deals from Roanoke to South Carolina. Data last updated August 5, 2026 and is based on user searches.
Discover last-minute flight deals from Roanoke to South Carolina. Data last updated August 5, 2026 and is based on user searches.
This Delta deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/136:00 am -
1 stop4h 20m
Mon 8/177:59 pm -
1 stop4h 28m
Deal found 7/31![Delta logo]()
$349
This Delta deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/176:00 am -
1 stop5h 54m
Wed 8/266:45 pm -
1 stop5h 42m
Deal found 8/3![Delta logo]()
$314
This Delta deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/207:59 pm -
1 stop4h 00m
Sun 8/236:45 pm -
1 stop5h 42m
Deal found 8/3![Delta logo]()
$329
This Kiwi.com deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/2010:51 am -
1 stop27h 15m
Sun 8/232:58 pm -
1 stop22h 48m
Deal found 8/4![Multiple Airlines logo]()
$343
This Delta deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/276:00 am -
1 stop4h 47m
Sun 8/307:02 pm -
1 stop5h 25m
Deal found 8/3![Delta logo]()
$327
This United Airlines deal was found by Cheapflights users on 8/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/16:40 am -
1 stop7h 18m
Sat 9/510:14 am -
1 stop4h 04m
Deal found 8/2![United Airlines logo]()
$341
This Delta deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/37:59 pm -
1 stop4h 00m
Sat 9/54:56 pm -
1 stop4h 42m
Deal found 8/1![Delta logo]()
$285
This United Airlines deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/36:15 am -
1 stop3h 48m
Thu 9/107:51 pm -
1 stop3h 52m
Deal found 8/1![United Airlines logo]()
$299
This American Airlines deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/151:57 pm -
1 stop4h 48m
Tue 9/228:08 am -
1 stop3h 35m
Deal found 8/3![American Airlines logo]()
$313
This Delta deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/206:00 am -
1 stop4h 08m
Sun 10/45:25 am -
1 stop5h 06m
Deal found 8/1![Delta logo]()
$334
This American Airlines deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/2212:11 pm -
1 stop4h 39m
Sat 9/265:31 pm -
1 stop3h 28m
Deal found 8/3![American Airlines logo]()
$271
This Delta deal was found by Cheapflights users on 8/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/226:00 am -
1 stop4h 07m
Mon 10/56:56 pm -
1 stop5h 03m
Deal found 8/2![Delta logo]()
$311
One-way flights from Roanoke to South CarolinaSearch for one-way flight options from Roanoke to South Carolina. Find affordable one-way fares based on user searches. Data last updated August 5, 2026.
Search for one-way flight options from Roanoke to South Carolina. Find affordable one-way fares based on user searches. Data last updated August 5, 2026.
This Kiwi.com deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/1310:51 am -
2 stops34h 05m
Deal found 8/3![Multiple Airlines logo]()
$179
This Kiwi.com deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/3010:51 am -
3 stops45h 10m
Deal found 7/31![Multiple Airlines logo]()
$232
This Kiwi.com deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/42:17 pm -
1 stop21h 27m
Deal found 7/31![Multiple Airlines logo]()
$238
This United Airlines deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/510:26 am -
1 stop3h 52m
Deal found 8/4![United Airlines logo]()
$240
This Delta deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/256:00 am -
1 stop4h 47m
Deal found 8/4![Delta logo]()
$252
This Kiwi.com deal was found by Cheapflights users on 8/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/103:27 pm -
1 stop17h 11m
Deal found 8/2![Multiple Airlines logo]()
$263
This Kiwi.com deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/11:42 pm -
3 stops42h 53m
Deal found 8/4![Multiple Airlines logo]()
$263
This United Airlines deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/48:05 pm -
1 stop22h 51m
Deal found 8/4![United Airlines logo]()
$274
This Kiwi.com deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/212:36 pm -
3 stops29h 01m
Deal found 8/4![Multiple Airlines logo]()
$275
This Kiwi.com deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/2810:12 am -
3 stops25h 04m
Deal found 7/31![Multiple Airlines logo]()
$276
This Kiwi.com deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/303:48 pm -
3 stops28h 07m
Deal found 8/1![Multiple Airlines logo]()
$279
This Kiwi.com deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/11:50 pm -
2 stops42h 37m
Deal found 8/3![Multiple Airlines logo]()
$280
Find flight deals from Roanoke to South Carolina
Keep the following information in mind while searching for Roanoke to South Carolina flight deals. Data was last updated August 5, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $271 (American Airlines) |
One-way from | $179 (Kiwi.com) |
Popular in | June |
Cheapest in | January |
Average price | $486 |
Cheapflights Fare Finder
Customize your flight search to find flights from Roanoke to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 5, 2026.
Use the filters below to find and compare flights from Roanoke to South Carolina that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
RoanokeCharleston
ROA - CHS
ROACHS
Roanoke
Sat 10/10
6:00 am-9:25 am
1 stop3h 25m
Charleston
Mon 10/12
5:30 am-10:32 am
1 stop5h 02m
$285
RoanokeCharleston
ROA - CHS
ROACHS
Roanoke
Thu 9/3
7:59 pm-11:59 pm
1 stop4h 00m
Charleston
Sat 9/5
4:56 pm-9:38 pm
1 stop4h 42m
$285
RoanokeMyrtle Beach
ROA - MYR
ROAMYR
Roanoke
Thu 9/10
4:46 pm-9:41 pm
1 stop4h 55m
Myrtle Beach Intl
Thu 9/17
6:56 pm-11:59 pm
1 stop5h 03m
$311
RoanokeMyrtle Beach
ROA - MYR
ROAMYR
Roanoke
Tue 9/15
6:00 am-10:07 am
1 stop4h 07m
Myrtle Beach Intl
Tue 9/22
6:00 am-10:31 am
1 stop4h 31m
$311
RoanokeCharleston
ROA - CHS
ROACHS
Roanoke
Thu 9/17
6:32 pm-11:59 pm
1 stop5h 27m
Charleston
Thu 9/24
6:52 pm-11:59 pm
1 stop5h 07m
$314
RoanokeMyrtle Beach
ROA - MYR
ROAMYR
Roanoke
Thu 8/27
6:00 am-10:47 am
1 stop4h 47m
Myrtle Beach Intl
Sun 8/30
7:02 pm-12:27 am
1 stop5h 25m
$327
RoanokeCharleston
ROA - CHS
ROACHS
Roanoke
Thu 9/24
6:32 pm-11:59 pm
1 stop5h 27m
Charleston
Sun 9/27
5:25 am-10:31 am
1 stop5h 06m
$334
RoanokeCharleston
ROA - CHS
ROACHS
Roanoke
Sun 9/20
6:00 am-10:08 am
1 stop4h 08m
Charleston
Sun 10/4
5:25 am-10:31 am
1 stop5h 06m
$334
RoanokeCharleston
ROA - CHS
ROACHS
Roanoke
Tue 9/1
10:26 am-3:10 pm
1 stop4h 44m
Charleston
Sat 9/5
11:40 am-5:09 pm
1 stop5h 29m
$341
RoanokeMyrtle Beach
ROA - MYR
ROAMYR
Roanoke
Sat 9/5
5:02 pm-9:49 pm
1 stop4h 47m
Myrtle Beach Intl
Sat 9/12
6:00 am-10:31 am
1 stop4h 31m
$385
Showing 1-10 of 43 resultsSorted by cheapest first
Best time to book a flight from Roanoke to South Carolina
Have a flexible travel schedule? Discover the best time to fly to South Carolina from Roanoke with our price prediction graph.
ROA-CHS
ROA-MYR
ROA-CLT
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Roanoke to South Carolina
ROA-USSC
ROA-CHS
ROA-MYR
ROA-CLT
What is the cheapest month to book a flight from Roanoke to South Carolina?
Currently, January is the cheapest month in which you can book a flight from Roanoke to South Carolina (average of $228). Flying from Roanoke to South Carolina in April is currently the most expensive (average of $686). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
Reviews of airlines servicing South Carolina
Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated August 5, 2026.
Read through reviews of airlines operating flights from Roanoke to South Carolina, such as American Airlines. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Comfort
7.2
Overall
7.1
Entertainment
6.8
Boarding
7.5
Food
6.4
Crew
7.9
Reviews
1 / 20
10.0
ExcellentLinda,Jul 2026
ROA - CLT
Comfort
7.2
Overall
7.1
Entertainment
6.8
Boarding
7.5
Food
6.4
Crew
7.9
Reviews
1 / 20
10.0
ExcellentLinda,Jul 2026
ROA - CLT
Related info for your journey
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Alternative routes for Roanoke to South Carolina
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Complete your trip
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Roanoke and South Carolina flights
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Roanoke to South Carolina flights
Consider these flights traveling from Roanoke to South Carolina.
Top airline flying from Roanoke to South Carolina
Discover the top airline that operate flights from Roanoke to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 5, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$218 | Average$468 | FlexibilityNo cancel fee | On-time71% |