$165+ Cheap flights from Roanoke (ROA) to South Carolina
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/20. Fares are subject to change and may not be available on all flights or dates of travel.
ROA — CHS
Dec 9 — Dec 161
Round-trip
1 adult, Economy
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Find cheap flights from Roanoke to South Carolina with Cheapflights
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Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from Roanoke to South CarolinaExplore the most affordable flight options available from Roanoke to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 9, 2026.
Explore the most affordable flight options available from Roanoke to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 9, 2026.
This Delta deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/206:00 am -
1 stop4h 20m
Sun 12/208:17 pm -
1 stop3h 55m
Deal found 11/5![Delta logo]()
$329
This Delta deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/136:55 pm -
1 stop3h 27m
Wed 12/307:41 pm -
1 stop4h 31m
Deal found 11/6![Delta logo]()
$339
This United Airlines deal was found by Cheapflights users on 11/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/222:55 pm -
1 stop4h 13m
Thu 11/2610:16 am -
1 stop3h 59m
Deal found 11/7![United Airlines logo]()
$349
This United Airlines deal was found by Cheapflights users on 11/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/2210:26 am -
1 stop4h 02m
Thu 11/262:52 pm -
1 stop4h 15m
Deal found 11/7![United Airlines logo]()
$359
This American Airlines deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/146:10 am -
1 stop3h 38m
Tue 12/16:20 am -
1 stop4h 09m
Deal found 11/5![American Airlines logo]()
$364
This United Airlines deal was found by Cheapflights users on 11/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/2210:26 am -
1 stop3h 50m
Thu 11/2610:26 am -
1 stop3h 49m
Deal found 11/7![United Airlines logo]()
$369
This Delta deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/136:00 am -
1 stop3h 40m
Sun 1/37:41 pm -
1 stop4h 31m
Deal found 11/6![Delta logo]()
$399
This Kiwi.com deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/192:37 pm -
1 stop24h 01m
Sun 1/33:28 pm -
1 stop25h 55m
Deal found 11/6![Allegiant Air logo]()
$411
This American Airlines deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/225:01 am -
1 stop3h 28m
Wed 11/253:14 pm -
1 stop6h 28m
Deal found 11/8![American Airlines logo]()
$429
This Delta deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/46:55 pm -
1 stop3h 52m
Sun 12/66:57 pm -
1 stop5h 29m
Deal found 11/5![Delta logo]()
$437
This Delta deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/166:55 pm -
1 stop3h 27m
Sat 1/27:41 pm -
1 stop4h 31m
Deal found 11/6![Delta logo]()
$449
This Kiwi.com deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/192:37 pm -
1 stop24h 01m
Wed 12/302:33 pm -
1 stop24h 34m
Deal found 11/6![Allegiant Air logo]()
$479
Best flights from Roanoke to South CarolinaDiscover carefully curated flight deals from Roanoke to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated November 9, 2026.
Discover carefully curated flight deals from Roanoke to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated November 9, 2026.
This Delta deal was found by Cheapflights users on 11/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/207:50 pm -
1 stop4h 06m
Fri 3/267:59 pm -
1 stop4h 24m
Deal found 11/7![Delta logo]()
$325
This American Airlines deal was found by Cheapflights users on 11/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/54:58 pm -
1 stop6h 03m
Sat 12/1210:54 am -
1 stop5h 34m
Deal found 11/7![American Airlines logo]()
$339
This United Airlines deal was found by Cheapflights users on 11/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/222:55 pm -
1 stop4h 13m
Thu 11/2610:16 am -
1 stop3h 59m
Deal found 11/7![United Airlines logo]()
$349
This Kiwi.com deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/192:37 pm -
1 stop24h 01m
Sun 12/273:28 pm -
1 stop25h 55m
Deal found 11/9![Allegiant Air logo]()
$539
This Delta deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/156:00 am -
1 stop3h 42m
Sun 4/188:30 am -
1 stop6h 10m
Deal found 11/6![Delta logo]()
$329
This United Airlines deal was found by Cheapflights users on 11/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/2210:26 am -
1 stop4h 02m
Thu 11/262:52 pm -
1 stop4h 15m
Deal found 11/7![United Airlines logo]()
$359
This Delta deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/123:25 pm -
1 stop5h 16m
Sun 3/147:59 pm -
1 stop4h 24m
Deal found 11/9![Delta logo]()
$329
This Delta deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/206:00 am -
1 stop4h 20m
Sun 12/208:17 pm -
1 stop3h 55m
Deal found 11/5![Delta logo]()
$329
This United Airlines deal was found by Cheapflights users on 11/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals ”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/2210:26 am -
1 stop3h 50m
Thu 11/2610:26 am -
1 stop3h 49m
Deal found 11/7![United Airlines logo]()
$369
This Delta deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/146:55 pm -
1 stop3h 27m
Sat 1/27:41 pm -
1 stop4h 31m
Deal found 11/6![Delta logo]()
$339
This Delta deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/156:00 am -
1 stop3h 40m
Thu 12/318:00 am -
1 stop4h 39m
Deal found 11/6![Delta logo]()
$339
This American Airlines deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/266:25 am -
1 stop3h 48m
Sat 1/28:10 pm -
1 stop3h 46m
Deal found 11/8![American Airlines logo]()
$500
This American Airlines deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/244:14 pm -
1 stop3h 40m
Sat 11/288:35 pm -
1 stop3h 03m
Deal found 11/9![American Airlines logo]()
$528
This United Airlines deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/110:20 am -
1 stop3h 53m
Wed 5/510:23 am -
1 stop3h 35m
Deal found 11/5![United Airlines logo]()
$533
This Delta deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/311:27 am -
1 stop6h 49m
Sat 2/610:26 am -
1 stop6h 22m
Deal found 11/9![Delta logo]()
$417
This American Airlines deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/216:15 am -
1 stop4h 12m
Sat 11/288:35 pm -
1 stop3h 03m
Deal found 11/5![American Airlines logo]()
$571
This United Airlines deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/2910:00 am -
2 stops23h 19m
Mon 2/112:50 pm -
1 stop8h 54m
Deal found 11/5![United Airlines logo]()
$563
This Delta deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/46:55 pm -
1 stop3h 52m
Sun 12/66:57 pm -
1 stop5h 29m
Deal found 11/5![Delta logo]()
$437
This American Airlines deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/36:00 am -
2 stops7h 05m
Sat 2/66:00 am -
1 stop4h 13m
Deal found 11/9![American Airlines logo]()
$587
This American Airlines deal was found by Cheapflights users on 11/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/225:01 am -
1 stop3h 28m
Thu 11/266:51 am -
2 stops25h 34m
Deal found 11/7![American Airlines logo]()
$592
This Delta deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/186:00 am -
1 stop5h 13m
Thu 12/314:07 pm -
1 stop4h 41m
Deal found 11/6![Delta logo]()
$449
This United Airlines deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/226:00 am -
1 stop4h 06m
Wed 11/253:35 pm -
2 stops22h 40m
Deal found 11/8![United Airlines logo]()
$603
This United Airlines deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/232:55 pm -
1 stop4h 13m
Fri 11/277:54 pm -
1 stop3h 50m
Deal found 11/8![United Airlines logo]()
$613
This Delta deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/197:55 pm -
1 stop13h 29m
Sat 1/27:41 pm -
1 stop4h 31m
Deal found 11/6![Delta logo]()
$512
This American Airlines deal was found by Cheapflights users on 11/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/222:18 pm -
1 stop5h 36m
Thu 11/266:50 am -
2 stops25h 35m
Deal found 11/7![American Airlines logo]()
$692
This United Airlines deal was found by Cheapflights users on 11/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/53:05 pm -
2 stops20h 29m
Sat 12/126:30 am -
1 stop6h 59m
Deal found 11/7![United Airlines logo]()
$638
This Delta deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/197:55 pm -
1 stop13h 29m
Mon 1/45:47 pm -
1 stop6h 29m
Deal found 11/6![Delta logo]()
$512
This Delta deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/213:55 pm -
1 stop4h 15m
Wed 11/256:05 pm -
1 stop6h 14m
Deal found 11/6![Delta logo]()
$552
This United Airlines deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/33:05 pm -
2 stops26h 43m
Sat 2/66:29 pm -
3 stops30h 16m
Deal found 11/9![United Airlines logo]()
$830
This Delta deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/96:00 am -
1 stop4h 07m
Fri 12/116:00 am -
1 stop4h 37m
Deal found 11/6![Delta logo]()
$595
Last-minute flights from Roanoke to South CarolinaDiscover last-minute flight deals from Roanoke to South Carolina. Data last updated November 9, 2026 and is based on user searches.
Discover last-minute flight deals from Roanoke to South Carolina. Data last updated November 9, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/146:10 am -
1 stop3h 38m
Tue 12/16:20 am -
1 stop4h 09m
Deal found 11/5![American Airlines logo]()
$364
This United Airlines deal was found by Cheapflights users on 11/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/222:55 pm -
1 stop4h 13m
Thu 11/2610:16 am -
1 stop3h 59m
Deal found 11/7![United Airlines logo]()
$349
This United Airlines deal was found by Cheapflights users on 11/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/2210:26 am -
1 stop4h 02m
Thu 11/262:52 pm -
1 stop4h 15m
Deal found 11/7![United Airlines logo]()
$359
This United Airlines deal was found by Cheapflights users on 11/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/2210:26 am -
1 stop3h 50m
Thu 11/2610:26 am -
1 stop3h 49m
Deal found 11/7![United Airlines logo]()
$369
This American Airlines deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/225:01 am -
1 stop3h 28m
Wed 11/253:14 pm -
1 stop6h 28m
Deal found 11/8![American Airlines logo]()
$429
This Delta deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/46:55 pm -
1 stop3h 52m
Sun 12/66:57 pm -
1 stop5h 29m
Deal found 11/5![Delta logo]()
$437
This Delta deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/136:55 pm -
1 stop3h 27m
Sat 1/27:41 pm -
1 stop4h 31m
Deal found 11/6![Delta logo]()
$339
This Delta deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/136:00 am -
1 stop3h 40m
Sun 1/37:41 pm -
1 stop4h 31m
Deal found 11/6![Delta logo]()
$399
This Delta deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/166:55 pm -
1 stop3h 27m
Mon 1/45:38 am -
1 stop5h 06m
Deal found 11/6![Delta logo]()
$449
This Kiwi.com deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/192:37 pm -
1 stop24h 01m
Sun 1/33:28 pm -
1 stop25h 55m
Deal found 11/6![Allegiant Air logo]()
$411
This Kiwi.com deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/192:37 pm -
1 stop24h 01m
Wed 12/302:33 pm -
1 stop24h 34m
Deal found 11/6![Allegiant Air logo]()
$479
This Delta deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/206:00 am -
1 stop4h 20m
Sun 12/208:17 pm -
1 stop3h 55m
Deal found 11/5![Delta logo]()
$329
One-way flights from Roanoke to South CarolinaSearch for one-way flight options from Roanoke to South Carolina. Find affordable one-way fares based on user searches. Data last updated November 9, 2026.
Search for one-way flight options from Roanoke to South Carolina. Find affordable one-way fares based on user searches. Data last updated November 9, 2026.
This American Airlines deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/208:27 am -
1 stop5h 12m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/5![American Airlines logo]()
$165
This Delta deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/276:00 am -
1 stop4h 07m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/5![Delta logo]()
$318
This American Airlines deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/54:58 pm -
1 stop4h 32m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/9![American Airlines logo]()
$343
This Delta deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/26:00 am -
1 stop3h 24m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/9![Delta logo]()
$364
This Delta deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/276:00 am -
1 stop4h 20m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/4![Delta logo]()
$388
This Delta deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/86:00 am -
1 stop3h 24m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/9![Delta logo]()
$404
This American Airlines deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/273:11 pm -
2 stops6h 52m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/5![American Airlines logo]()
$418
This United Airlines deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/208:05 pm -
2 stops25h 56m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/5![United Airlines logo]()
$425
This Kiwi.com deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/293:57 pm -
3 stops41h 58m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/6![Multiple Airlines logo]()
$512
This Kiwi.com deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/2710:51 am -
3 stops22h 37m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/5![Multiple Airlines logo]()
$520
This United Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/273:00 pm -
2 stops8h 59m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/4![United Airlines logo]()
$531
This Delta deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/296:00 am -
1 stop4h 07m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/6![Delta logo]()
$545
Find flight deals from Roanoke to South Carolina
Keep the following information in mind while searching for Roanoke to South Carolina flight deals. Data was last updated November 9, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $325 (Delta) |
One-way from | $165 (American Airlines) |
Popular in | September |
Cheapest in | February |
Average price | $417 |
Cheapflights Fare Finder
Customize your flight search to find flights from Roanoke to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated November 9, 2026.
Use the filters below to find and compare flights from Roanoke to South Carolina that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
RoanokeCharleston
ROA Roanoke - CHS Charleston
ROACHS
Roanoke
Sun 12/20
8:27 am-1:39 pm
1 stop5h 12m
Charleston
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$165
RoanokeMyrtle Beach
ROA Roanoke - MYR Myrtle Beach Intl
ROAMYR
Roanoke
Fri 11/27
6:00 am-10:07 am
1 stop4h 07m
Myrtle Beach Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$318
RoanokeCharleston
ROA Roanoke - CHS Charleston
ROACHS
Roanoke
Sat 3/20
7:50 pm-11:56 pm
1 stop4h 06m
Charleston
Fri 3/26
7:59 pm-12:23 am
1 stop4h 24m
$325
RoanokeCharleston
ROA Roanoke - CHS Charleston
ROACHS
Roanoke
Thu 4/15
6:00 am-9:42 am
1 stop3h 42m
Charleston
Sun 4/18
8:30 am-2:40 pm
1 stop6h 10m
$329
RoanokeCharleston
ROA Roanoke - CHS Charleston
ROACHS
Roanoke
Fri 3/12
3:25 pm-8:41 pm
1 stop5h 16m
Charleston
Sun 3/14
7:59 pm-12:23 am
1 stop4h 24m
$329
RoanokeCharleston
ROA Roanoke - CHS Charleston
ROACHS
Roanoke
Sun 12/20
6:00 am-10:20 am
1 stop4h 20m
Charleston
Sun 12/20
8:17 pm-12:12 am
1 stop3h 55m
$329
RoanokeGreenville
ROA Roanoke - GSP Greenville
ROAGSP
Roanoke
Sat 12/5
4:58 pm-11:01 pm
1 stop6h 03m
Greenville
Sat 12/12
10:54 am-4:28 pm
1 stop5h 34m
$339
RoanokeGreenville
ROA Roanoke - GSP Greenville
ROAGSP
Roanoke
Mon 12/14
6:55 pm-10:22 pm
1 stop3h 27m
Greenville
Sat 1/2
7:41 pm-12:12 am
1 stop4h 31m
$339
RoanokeGreenville
ROA Roanoke - GSP Greenville
ROAGSP
Roanoke
Tue 12/15
6:00 am-9:40 am
1 stop3h 40m
Greenville
Thu 12/31
8:00 am-12:39 pm
1 stop4h 39m
$339
RoanokeColumbia
ROA Roanoke - CAE Columbia Metropolitan
ROACAE
Roanoke
Sun 11/22
2:55 pm-7:08 pm
1 stop4h 13m
Columbia Metropolitan
Thu 11/26
10:16 am-2:15 pm
1 stop3h 59m
$349
Showing 1-10 of 45 resultsSorted by cheapest first
Best time to book a flight from Roanoke to South Carolina
Have a flexible travel schedule? Discover the best time to fly to South Carolina from Roanoke with our price prediction graph.
ROA-CHS
ROA-GSP
ROA-CAE
ROA-MYR
ROA-HHH
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Roanoke to South Carolina
ROA-USSC
ROA-CHS
ROA-GSP
ROA-CAE
ROA-MYR
What is the cheapest month to book a flight from Roanoke to South Carolina?
Currently, January is the cheapest month in which you can book a flight from Roanoke to South Carolina (average of $228). Flying from Roanoke to South Carolina in April is currently the most expensive (average of $686). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
Reviews of airlines servicing South Carolina
Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated November 9, 2026.
Read through reviews of airlines operating flights from Roanoke to South Carolina, such as American Airlines. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
6.8
Comfort
7.2
Overall
7.0
Boarding
7.4
Crew
7.9
Food
6.4
Reviews
1 / 20
10.0
ExcellentLinda,Jul 2026
ROA - CLT
Entertainment
6.8
Comfort
7.2
Overall
7.0
Boarding
7.4
Crew
7.9
Food
6.4
Reviews
1 / 20
10.0
ExcellentLinda,Jul 2026
ROA - CLT
Related info for your journey
Find useful and relevant information for your journey from Roanoke to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Roanoke to South Carolina
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Complete your trip
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Roanoke and South Carolina flights
Browse other Roanoke and South Carolina flight options. Last updated on November 9, 2026.
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Roanoke to South Carolina flights
Consider these flights traveling from Roanoke to South Carolina.
Top airline flying from Roanoke to South Carolina
Discover the top airline that operate flights from Roanoke to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated November 9, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$144 | Average$445 | FlexibilityNo cancel fee | On-time71% |