How long is the flight from Mississippi to Roanoke?

Delta, American Airlines, and United Airlines can get you from Mississippi to Roanoke in just under 6h 18m. Your travel time can differ by up to 5h 19m. Airlines will cover a distance of 579 mi. Both multi-stop and nonstop flights can be found to your destination and back.

In terms of precipitation, rainfall in Roanoke ranges from 2.9 - 4.1 inches per month. May is typically the wettest month, when rainfall can reach 4.1 in. January is typically the driest time to visit Roanoke when rainfall is around 2.9 in.

If weather is an important factor for your trip to Roanoke, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 77.0 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 37.4 F).

What airport do you fly into for flights to Roanoke from Mississippi?

Roanoke (ROA), located 4.2 mi from the city center, is the airport you fly into when you book flights from Mississippi to Roanoke.

Can I find deals for flights from Mississippi to Roanoke that include hotel bookings?

Yes. In addition to deals on Mississippi to Roanoke flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Mississippi to Roanoke?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Mississippi to Roanoke.

Can I find deals for business class flights from Mississippi to Roanoke?

Yes. Cheapflights offers flight deals from Mississippi to Roanoke by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$249+ Flights from Mississippi to Roanoke

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Cheap flight deals from Mississippi to Roanoke

Cheapest flights from Mississippi to Roanoke
Explore the most affordable flight options available from Mississippi to Roanoke. Find the lowest fares from popular airlines and budget airlines, with prices last updated on diciembre 16, 2025.

lun. 12/295:00 amMEM - ROA

1 stop4h 31mAmerican Airlines

vie. 1/27:07 pmROA - MEM

1 stop5h 49mAmerican Airlines

Deal found 12/13

$279

sáb. 12/206:00 amMEM - ROA

1 stop6h 50mDelta

vie. 12/266:00 amROA - MEM

1 stop3h 45mDelta

Deal found 12/13

$339

lun. 12/2910:35 amMEM - ROA

1 stop5h 26mUnited Airlines

vie. 1/26:15 amROA - MEM

2 stops9h 33mUnited Airlines

Deal found 12/13

$344

sáb. 12/202:48 pmMEM - ROA

1 stop5h 10mUnited Airlines

vie. 12/265:42 pmROA - MEM

1 stop5h 16mUnited Airlines

Deal found 12/15

$439

mié. 12/173:01 pmMEM - ROA

1 stop4h 44mUnited Airlines

vie. 12/195:42 pmROA - MEM

1 stop22h 06mUnited Airlines

Deal found 12/13

$776

Best flights from Mississippi to Roanoke
Discover carefully curated flight deals from Mississippi to Roanoke that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated diciembre 16, 2025.

mié. 2/1811:59 amMEM - ROA

1 stop6h 18mDelta

sáb. 2/217:59 pmROA - MEM

1 stop4h 18mDelta

Deal found 12/14

$269

mié. 2/1811:34 amMEM - ROA

2 stops7h 55mAmerican Airlines

sáb. 2/218:00 pmROA - MEM

1 stop4h 58mAmerican Airlines

Deal found 12/14

$274

sáb. 2/217:30 amMEM - ROA

2 stops11h 37mUnited Airlines

mié. 2/256:40 amROA - MEM

1 stop5h 17mUnited Airlines

Deal found 12/13

$344

lun. 12/2910:35 amMEM - ROA

1 stop5h 26mUnited Airlines

vie. 1/26:15 amROA - MEM

2 stops9h 33mUnited Airlines

Deal found 12/13

$344

mié. 2/187:30 amMEM - ROA

2 stops11h 37mUnited Airlines

sáb. 2/2110:15 amROA - MEM

2 stops8h 27mUnited Airlines

Deal found 12/14

$347

sáb. 1/312:00 pmJAN - ROA

2 stops23h 09mUnited Airlines

mar. 2/310:15 amROA - JAN

2 stops12h 42mUnited Airlines

Deal found 12/15

$551

Last-minute flights from Mississippi to Roanoke
Discover last-minute flight deals from Mississippi to Roanoke. Data last updated diciembre 16, 2025 and is based on user searches.

mié. 12/173:01 pmMEM - ROA

1 stop4h 44mUnited Airlines

vie. 12/195:42 pmROA - MEM

1 stop22h 06mUnited Airlines

Deal found 12/13

$776

sáb. 12/206:00 amMEM - ROA

1 stop6h 50mDelta

vie. 12/266:00 amROA - MEM

1 stop3h 45mDelta

Deal found 12/13

$339

sáb. 12/202:48 pmMEM - ROA

1 stop5h 10mUnited Airlines

vie. 12/265:42 pmROA - MEM

1 stop5h 16mUnited Airlines

Deal found 12/15

$439

lun. 12/295:00 amMEM - ROA

1 stop4h 31mAmerican Airlines

vie. 1/27:07 pmROA - MEM

1 stop5h 49mAmerican Airlines

Deal found 12/13

$279

lun. 12/2910:35 amMEM - ROA

1 stop5h 26mUnited Airlines

vie. 1/26:15 amROA - MEM

2 stops9h 33mUnited Airlines

Deal found 12/13

$344

sáb. 1/312:00 pmJAN - ROA

2 stops23h 09mUnited Airlines

mar. 2/310:15 amROA - JAN

2 stops12h 42mUnited Airlines

Deal found 12/15

$551

One-way flights from Mississippi to Roanoke
Search for one-way flight options from Mississippi to Roanoke. Find affordable one-way fares based on user searches. Data last updated diciembre 16, 2025.

jue. 1/156:00 amMEM - ROA

1 stop6h 40mDelta

Deal found 12/13

$249

jue. 1/156:35 amMEM - ROA

2 stops8h 35mAmerican Airlines

Deal found 12/13

$254

jue. 1/1510:40 amMEM - ROA

3 stops27h 23mAllegiant Air

Deal found 12/13

$481

Find flight deals from Mississippi to Roanoke

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Round-trip from	$269 (Delta)
One-way from	$249 (Delta)

Provider with most accurate pricing for Jackson-Evers Intl-Roanoke flight deals.

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From Mississippi to Roanoke

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One-way flight from Mississippi to Roanoke

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Use the filters below to find and compare flights from Mississippi to Roanoke that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

MemphisRoanoke

MEM - ROA

MEMROA

Memphis

mié. 2/18

11:59 am-7:17 pm

1 stop6h 18m

Roanoke

sáb. 2/21

7:59 pm-11:17 pm

1 stop4h 18m

$269

MemphisRoanoke

MEM - ROA

MEMROA

Memphis

mié. 2/18

11:34 am-8:29 pm

2 stops7h 55m

Roanoke

sáb. 2/21

8:00 pm-11:58 pm

1 stop4h 58m

$274

MemphisRoanoke

MEM - ROA

MEMROA

Memphis

sáb. 2/21

7:30 am-8:07 pm

2 stops11h 37m

Roanoke

mié. 2/25

6:40 am-10:57 am

1 stop5h 17m

$344

MemphisRoanoke

MEM - ROA

MEMROA

Memphis

lun. 12/29

10:35 am-5:01 pm

1 stop5h 26m

Roanoke

vie. 1/2

6:15 am-2:48 pm

2 stops9h 33m

$344

MemphisRoanoke

MEM - ROA

MEMROA

Memphis

mié. 2/18

7:30 am-8:07 pm

2 stops11h 37m

Roanoke

sáb. 2/21

10:15 am-5:42 pm

2 stops8h 27m

$347

JacksonRoanoke

JAN - ROA

JANROA

Jackson-Evers Intl

sáb. 1/31

2:00 pm-2:09 pm

2 stops23h 09m

Roanoke

mar. 2/3

10:15 am-9:57 pm

2 stops12h 42m

$551

MemphisRoanoke

MEM - ROA

MEMROA

Memphis

jue. 1/15

6:00 am-1:40 pm

1 stop6h 40m

$249

MemphisRoanoke

MEM - ROA

MEMROA

Memphis

jue. 1/15

6:35 am-4:10 pm

2 stops8h 35m

$254

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/13

Best time to book a flight from Mississippi to Roanoke

Have a flexible travel schedule? Discover the best time to fly to Roanoke from Mississippi with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Mississippi to Roanoke

What is the cheapest time of day to fly from MS to ROA?

It’s optimal to fly from Mississippi to Roanoke in the evening. By choosing this option you can save up to 27% on the cost of your flight, compared to a flight in the morning.

Related info for your journey

What airport do you fly into for flights to Roanoke from Mississippi?
Roanoke (ROA), located 4.2 mi from the city center, is the airport you fly into when you book flights from Mississippi to Roanoke.
How long is the flight from Mississippi to Roanoke?
Delta, American Airlines, and United Airlines can get you from Mississippi to Roanoke in just under 6h 18m. Your travel time can differ by up to 5h 19m. Airlines will cover a distance of 579 mi. Both multi-stop and nonstop flights can be found to your destination and back.
Can I find deals for flights from Mississippi to Roanoke that include hotel bookings?
Yes. In addition to deals on Mississippi to Roanoke flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Mississippi to Roanoke?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Mississippi to Roanoke.
Can I find deals for business class flights from Mississippi to Roanoke?
Yes. Cheapflights offers flight deals from Mississippi to Roanoke by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Radford

Salem

Blacksburg

Christiansburg

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$249+ Cheap flights from Mississippi to Roanoke (ROA)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/15. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Mississippi to Roanoke with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Cheap flight deals from Mississippi to Roanoke

Cheapest flights from Mississippi to RoanokeExplore the most affordable flight options available from Mississippi to Roanoke. Find the lowest fares from popular airlines and budget airlines, with prices last updated on diciembre 16, 2025.

Explore the most affordable flight options available from Mississippi to Roanoke. Find the lowest fares from popular airlines and budget airlines, with prices last updated on diciembre 16, 2025.

Find flight deals from Mississippi to Roanoke

Keep the following information in mind while searching for Mississippi to Roanoke flight deals. Data was last updated diciembre 16, 2025.

Most accurate provider

Most trusted provider

Round-trip from

One-way from

Cheapflights Fare Finder

Use the filters below to find and compare flights from Mississippi to Roanoke that are best for you.

Best time to book a flight from Mississippi to Roanoke

Have a flexible travel schedule? Discover the best time to fly to Roanoke from Mississippi with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Mississippi to Roanoke

What is the cheapest time of day to fly from MS to ROA?

Find hourly flight availability from Mississippi to Roanoke. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated diciembre 16, 2025.

Related info for your journey

Find useful and relevant information for your journey from Mississippi to Roanoke. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What airport do you fly into for flights to Roanoke from Mississippi?

How long is the flight from Mississippi to Roanoke?

Can I find deals for flights from Mississippi to Roanoke that include hotel bookings?

How can I find direct flights from Mississippi to Roanoke?

Can I find deals for business class flights from Mississippi to Roanoke?

Traveling to a place near Roanoke?

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Cheapest flights from Mississippi to Roanoke
Explore the most affordable flight options available from Mississippi to Roanoke. Find the lowest fares from popular airlines and budget airlines, with prices last updated on diciembre 16, 2025.