HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Roanoke

$249+ Cheap flights from Mississippi to Roanoke (ROA)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/5. Fares are subject to change and may not be available on all flights or dates of travel.
JAN — ROA
Dec 13 — Dec 201
Sat 12/13
Sat 12/20
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Mississippi to Roanoke with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Find flight deals from Mississippi to Roanoke

Cheapest flights from Mississippi to Roanoke
Explore the most affordable flight options available from Mississippi to Roanoke. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 13, 2025.

This Delta deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/56:00 amMEM - ROA
1 stop3h 40mDelta
Sun 12/78:00 pmROA - MEM
1 stop4h 23mDelta
Deal found 11/12$249
This Delta deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/256:00 amMEM - ROA
1 stop3h 40mDelta
Fri 11/286:00 amROA - MEM
1 stop4h 22mDelta
Deal found 11/10$279
This American Airlines deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/276:50 amMEM - ROA
1 stop6h 32mAmerican Airlines
Mon 12/18:06 pmROA - MEM
1 stop4h 53mAmerican Airlines
Deal found 11/12$309
This United Airlines deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/2510:30 amMEM - ROA
2 stops12h 00mUnited Airlines
Fri 11/286:45 amROA - MEM
1 stop5h 11mUnited Airlines
Deal found 11/10$354
This United Airlines deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/57:39 amMEM - ROA
2 stops10h 17mUnited Airlines
Sun 12/76:45 amROA - MEM
1 stop5h 11mUnited Airlines
Deal found 11/12$359
This American Airlines deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/259:23 amMEM - ROA
2 stops7h 11mAmerican Airlines
Fri 11/285:05 amROA - MEM
1 stop4h 11mAmerican Airlines
Deal found 11/10$362
This United Airlines deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/53:01 pmMEM - ROA
1 stop4h 44mUnited Airlines
Mon 12/85:40 pmROA - MEM
1 stop5h 19mUnited Airlines
Deal found 11/11$364
This United Airlines deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1910:30 amMEM - ROA
1 stop5h 26mUnited Airlines
Sun 11/236:20 amROA - MEM
2 stops9h 25mUnited Airlines
Deal found 11/12$429

Cheap flight deals from Mississippi to Roanoke

Keep the following information in mind while searching for Mississippi to Roanoke flight deals. Data was last updated November 13, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$249
(Delta)

Popular in

October

Cheapest in

May

Average price

$520
Provider with most accurate pricing for Jackson-Evers Intl-Roanoke flight deals.
Search Deals
Provider most trusted by Cheapflights users for Jackson-Evers Intl-Roanoke flights.
Search Deals
From Mississippi to Roanoke
Search Deals
Highest demand for flights based on searches. 34% potential increase in price ($188 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 10% potential price decrease ($36 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in November 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Mississippi to Roanoke that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 13, 2025.
Use the filters below to find and compare flights from Mississippi to Roanoke that are best for you.

Fly from

Mississippi

Fly to

Roanoke

Route

Depart

Return

Price

MemphisRoanoke

MEM - ROA

MEMROA

Memphis

Fri 12/5

6:00 am-10:40 am

1 stop3h 40m

Roanoke

Sun 12/7

8:00 pm-11:23 pm

1 stop4h 23m

$249

JacksonRoanoke

JAN - ROA

JANROA

Jackson-Evers Intl

Sat 2/21

2:57 pm-7:18 pm

1 stop3h 21m

Roanoke

Tue 2/24

7:59 pm-11:13 pm

1 stop4h 14m

$249

MemphisRoanoke

MEM - ROA

MEMROA

Memphis

Tue 11/25

6:00 am-10:40 am

1 stop3h 40m

Roanoke

Fri 11/28

6:00 am-9:22 am

1 stop4h 22m

$279

MemphisRoanoke

MEM - ROA

MEMROA

Memphis

Thu 11/27

6:50 am-2:22 pm

1 stop6h 32m

Roanoke

Mon 12/1

8:06 pm-11:59 pm

1 stop4h 53m

$309

JacksonRoanoke

JAN - ROA

JANROA

Jackson-Evers Intl

Sat 2/21

1:08 pm-9:26 pm

1 stop7h 18m

Roanoke

Tue 2/24

8:09 am-5:02 pm

2 stops9h 53m

$324

MemphisRoanoke

MEM - ROA

MEMROA

Memphis

Tue 11/25

10:30 am-11:30 pm

2 stops12h 00m

Roanoke

Fri 11/28

6:45 am-10:56 am

1 stop5h 11m

$354

MemphisRoanoke

MEM - ROA

MEMROA

Memphis

Fri 12/5

7:39 am-6:56 pm

2 stops10h 17m

Roanoke

Sun 12/7

6:45 am-10:56 am

1 stop5h 11m

$359

MemphisRoanoke

MEM - ROA

MEMROA

Memphis

Tue 11/25

9:23 am-5:34 pm

2 stops7h 11m

Roanoke

Fri 11/28

5:05 am-8:16 am

1 stop4h 11m

$362

MemphisRoanoke

MEM - ROA

MEMROA

Memphis

Fri 12/5

3:01 pm-8:45 pm

1 stop4h 44m

Roanoke

Mon 12/8

5:40 pm-9:59 pm

1 stop5h 19m

$364

MemphisRoanoke

MEM - ROA

MEMROA

Memphis

Mon 12/1

7:23 pm-12:15 am

1 stop3h 52m

Roanoke

Sat 12/6

6:00 am-11:42 am

1 stop6h 42m

$379

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/12

Showing 1-10 of 11 results
1
2

Best time to book a flight from Mississippi to Roanoke

Have a flexible travel schedule? Discover the best time to fly to Roanoke from Mississippi with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Mississippi to Roanoke

What is the cheapest month to book a flight from Mississippi to Roanoke?

Currently, May is the cheapest month in which you can book a flight from Mississippi to Roanoke (average of $149). Flying from Mississippi to Roanoke in April is currently the most expensive (average of $435). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MS to ROA?

Find hourly flight availability from Mississippi to Roanoke. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated November 13, 2025.

It’s optimal to fly from Mississippi to Roanoke in the evening. By choosing this option you can save up to 27% on the cost of your flight, compared to a flight in the morning.

Related info for your journey

Find useful and relevant information for your journey from Mississippi to Roanoke. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Roanoke from Mississippi?

    Roanoke (ROA), located 4.2 mi from the city center, is the airport you fly into when you book flights from Mississippi to Roanoke.

  • How long is the flight from Mississippi to Roanoke?

    Delta, American Airlines, and United Airlines can get you from Mississippi to Roanoke in just under 3h 40m. Your travel time can differ by up to 8h 20m. Airlines will cover a distance of 579 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • Can I find deals for flights from Mississippi to Roanoke that include hotel bookings?

    Yes. In addition to deals on Mississippi to Roanoke flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Mississippi to Roanoke?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Mississippi to Roanoke.

  • Can I find deals for business class flights from Mississippi to Roanoke?

    Yes. Cheapflights offers flight deals from Mississippi to Roanoke by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Mississippi to Roanoke?

    Currently, May is the cheapest month in which you can book a flight from Mississippi to Roanoke (average of $149). Flying from Mississippi to Roanoke in April is currently the most expensive (average of $435). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Roanoke?

Book flights to Roanoke if you plan to visit one of these locations
Radford
Salem
Blacksburg
Christiansburg

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Mississippi to Roanoke

See prices for flight routes from nearby airports that may be better suited for you.
Dallas/Fort Worth to Dulles Intl flights
Los Angeles to Reagan-National flights
Los Angeles to Dulles Intl flights
John F Kennedy Intl to Raleigh flights
Boston to Dulles Intl flights
Boston to Reagan-National flights
Atlanta to Dulles Intl flights
San Francisco to Reagan-National flights
O'Hare Intl to Reagan-National flights
Seattle to Reagan-National flights
O'Hare Intl to Dulles Intl flights
San Francisco to Dulles Intl flights
Denver to Dulles Intl flights
Seattle to Dulles Intl flights
Atlanta to Reagan-National flights
Hobby to Dulles Intl flights
Dallas/Fort Worth to Reagan-National flights
John F Kennedy Intl to Dulles Intl flights
LaGuardia to Raleigh flights
Tampa to Dulles Intl flights
Detroit to Dulles Intl flights
Hobby to Reagan-National flights
Orlando to Reagan-National flights
Newark to Raleigh flights
George Bush Intcntl to Dulles Intl flights
Austin to Dulles Intl flights
Tampa to Reagan-National flights
Denver to Reagan-National flights
Boston to Raleigh flights
Orlando to Dulles Intl flights
O'Hare Intl to Raleigh flights
John F Kennedy Intl to Reagan-National flights
Dallas/Fort Worth to Raleigh flights
Miami to Reagan-National flights
Denver to Raleigh flights
Miami to Dulles Intl flights
Sky Harbor Intl to Dulles Intl flights
San Francisco to Raleigh flights
Newark to Dulles Intl flights
Fort Lauderdale to Dulles Intl flights
Austin to Reagan-National flights
Minneapolis to Dulles Intl flights
Atlanta to Raleigh flights
George Bush Intcntl to Reagan-National flights
Los Angeles to Raleigh flights
Nashville to Reagan-National flights
Minneapolis to Reagan-National flights
LaGuardia to Reagan-National flights
Fort Lauderdale to Reagan-National flights
John F Kennedy Intl to Richmond flights

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.
Site
©2025 Cheapflights