How long is the flight from Mississippi to Roanoke?

United Airlines and American Airlines can get you from Mississippi to Roanoke in just under 6h 16m. Your travel time can differ by up to 2h 19m. Airlines will cover a distance of 579 mi. Both multi-stop and nonstop flights can be found to your destination and back.

In terms of precipitation, rainfall in Roanoke ranges from 2.9 - 4.1 inches per month. May is typically the wettest month, when rainfall can reach 4.1 in. January is typically the driest time to visit Roanoke when rainfall is around 2.9 in.

If weather is an important factor for your trip to Roanoke, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 77.0 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 37.4 F).

What is the cheapest time of day to fly from MS to ROA?

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Mississippi to Roanoke as you normally would.

What airport do you fly into for flights to Roanoke from Mississippi?

Roanoke (ROA), located 4.2 mi from the city center, is the airport you fly into when you book flights from Mississippi to Roanoke.

Can I find deals for flights from Mississippi to Roanoke that include hotel bookings?

Yes. In addition to deals on Mississippi to Roanoke flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Mississippi to Roanoke?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Mississippi to Roanoke.

Can I find deals for business class flights from Mississippi to Roanoke?

Yes. Cheapflights offers flight deals from Mississippi to Roanoke by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$309+ Flights from Mississippi to Roanoke

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Cheap flight deals from Mississippi to Roanoke

Best flights from Mississippi to Roanoke
Discover carefully curated flight deals from Mississippi to Roanoke that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated January 2, 2026.

Tue 1/137:30 amMEM - ROA

1 stop6h 16mUnited Airlines

Sat 1/175:39 pmROA - MEM

1 stop5h 15mUnited Airlines

Deal found 1/2

$309

Tue 1/136:35 amMEM - ROA

2 stops8h 35mAmerican Airlines

Sat 1/178:00 amROA - MEM

2 stops10h 08mAmerican Airlines

Deal found 1/2

$320

Thu 1/157:30 amMEM - ROA

1 stop6h 16mUnited Airlines

Mon 1/1912:40 pmROA - MEM

1 stop23h 14mUnited Airlines

Deal found 12/31

$453

Sat 1/177:30 amMEM - ROA

2 stops11h 01mUnited Airlines

Tue 1/2010:15 amROA - MEM

2 stops8h 11mUnited Airlines

Deal found 12/30

$510

Tue 1/205:15 pmJAN - ROA

2 stops25h 16mUnited Airlines

Sat 1/242:55 pmROA - JAN

2 stops26h 07mUnited Airlines

Deal found 12/30

$654

Last-minute flights from Mississippi to Roanoke
Discover last-minute flight deals from Mississippi to Roanoke. Data last updated January 2, 2026 and is based on user searches.

Tue 1/137:30 amMEM - ROA

1 stop6h 16mUnited Airlines

Sat 1/175:39 pmROA - MEM

1 stop5h 15mUnited Airlines

Deal found 1/2

$309

Tue 1/136:35 amMEM - ROA

2 stops8h 35mAmerican Airlines

Sat 1/178:00 amROA - MEM

2 stops10h 08mAmerican Airlines

Deal found 1/2

$320

Thu 1/157:30 amMEM - ROA

1 stop6h 16mUnited Airlines

Mon 1/1912:40 pmROA - MEM

1 stop23h 14mUnited Airlines

Deal found 12/31

$453

Sat 1/177:30 amMEM - ROA

2 stops11h 01mUnited Airlines

Tue 1/2012:40 pmROA - MEM

1 stop5h 46mUnited Airlines

Deal found 12/30

$504

Tue 1/205:15 pmJAN - ROA

2 stops25h 16mUnited Airlines

Sat 1/242:55 pmROA - JAN

2 stops26h 07mUnited Airlines

Deal found 12/30

$654

Find flight deals from Mississippi to Roanoke

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Round-trip from	$309 (United Airlines)

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From Mississippi to Roanoke

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Fly to

Route

Depart

Return

Price

MemphisRoanoke

MEM - ROA

MEMROA

Memphis

Tue 1/13

7:30 am-2:46 pm

1 stop6h 16m

Roanoke

Sat 1/17

5:39 pm-9:54 pm

1 stop5h 15m

$309

MemphisRoanoke

MEM - ROA

MEMROA

Memphis

Tue 1/13

6:35 am-4:10 pm

2 stops8h 35m

Roanoke

Sat 1/17

8:00 am-5:08 pm

2 stops10h 08m

$320

MemphisRoanoke

MEM - ROA

MEMROA

Memphis

Thu 1/15

7:30 am-2:46 pm

1 stop6h 16m

Roanoke

Mon 1/19

12:40 pm-10:54 am

1 stop23h 14m

$453

MemphisRoanoke

MEM - ROA

MEMROA

Memphis

Sat 1/17

7:30 am-7:31 pm

2 stops11h 01m

Roanoke

Tue 1/20

10:15 am-5:26 pm

2 stops8h 11m

$510

JacksonRoanoke

JAN - ROA

JANROA

Jackson-Evers Intl

Tue 1/20

5:15 pm-7:31 pm

2 stops25h 16m

Roanoke

Sat 1/24

2:55 pm-4:02 pm

2 stops26h 07m

$654

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/2

Best time to book a flight from Mississippi to Roanoke

Have a flexible travel schedule? Discover the best time to fly to Roanoke from Mississippi with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

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Everything you need to know about your flight from Mississippi to Roanoke

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Related info for your journey

What airport do you fly into for flights to Roanoke from Mississippi?
Roanoke (ROA), located 4.2 mi from the city center, is the airport you fly into when you book flights from Mississippi to Roanoke.
How long is the flight from Mississippi to Roanoke?
United Airlines and American Airlines can get you from Mississippi to Roanoke in just under 6h 16m. Your travel time can differ by up to 2h 19m. Airlines will cover a distance of 579 mi. Both multi-stop and nonstop flights can be found to your destination and back.
Can I find deals for flights from Mississippi to Roanoke that include hotel bookings?
Yes. In addition to deals on Mississippi to Roanoke flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Mississippi to Roanoke?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Mississippi to Roanoke.
Can I find deals for business class flights from Mississippi to Roanoke?
Yes. Cheapflights offers flight deals from Mississippi to Roanoke by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

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Radford

Salem

Blacksburg

Christiansburg

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$309+ Cheap flights from Mississippi to Roanoke (ROA)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/13. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Mississippi to Roanoke with Cheapflights

1. Tell us where you want to go

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3. Compare prices and book

Cheap flight deals from Mississippi to Roanoke

Best flights from Mississippi to RoanokeDiscover carefully curated flight deals from Mississippi to Roanoke that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated January 2, 2026.

Discover carefully curated flight deals from Mississippi to Roanoke that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated January 2, 2026.

Find flight deals from Mississippi to Roanoke

Keep the following information in mind while searching for Mississippi to Roanoke flight deals. Data was last updated January 2, 2026.

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Use the filters below to find and compare flights from Mississippi to Roanoke that are best for you.

Best time to book a flight from Mississippi to Roanoke

Have a flexible travel schedule? Discover the best time to fly to Roanoke from Mississippi with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Mississippi to Roanoke

Related info for your journey

Find useful and relevant information for your journey from Mississippi to Roanoke. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What airport do you fly into for flights to Roanoke from Mississippi?

How long is the flight from Mississippi to Roanoke?

Can I find deals for flights from Mississippi to Roanoke that include hotel bookings?

How can I find direct flights from Mississippi to Roanoke?

Can I find deals for business class flights from Mississippi to Roanoke?

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Best flights from Mississippi to Roanoke
Discover carefully curated flight deals from Mississippi to Roanoke that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated January 2, 2026.