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Roanoke

$249+ Cheap flights from Mississippi to Roanoke (ROA)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/18. Fares are subject to change and may not be available on all flights or dates of travel.
JAN — ROA
Nov 29 — Dec 61
Sat 11/29
Sat 12/6
1 adult, Economy
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Find flight deals from Mississippi to Roanoke

Cheapest flights from Mississippi to Roanoke
Explore the most affordable flight options available from Mississippi to Roanoke. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 30, 2025.

This Delta deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/137:23 pmMEM - ROA
1 stop3h 52mDelta
Sun 11/166:00 amROA - MEM
1 stop4h 24mDelta
Deal found 10/27$259
This Delta deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/122:31 pmMEM - ROA
1 stop3h 44mDelta
Sun 11/167:59 pmROA - MEM
1 stop4h 05mDelta
Deal found 10/28$279
This American Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1210:29 amMEM - ROA
2 stops9h 06mAmerican Airlines
Sun 11/165:05 amROA - MEM
1 stop4h 11mAmerican Airlines
Deal found 10/28$284
This United Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1910:30 amMEM - ROA
1 stop5h 26mUnited Airlines
Sun 11/236:45 amROA - MEM
1 stop5h 11mUnited Airlines
Deal found 10/28$319
This United Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/132:55 pmMEM - ROA
2 stops7h 35mUnited Airlines
Sun 11/166:45 amROA - MEM
1 stop5h 11mUnited Airlines
Deal found 10/27$348
This United Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1310:30 amMEM - ROA
1 stop5h 26mUnited Airlines
Mon 11/175:38 pmROA - MEM
1 stop5h 20mUnited Airlines
Deal found 10/29$433
This United Airlines deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/147:30 amMEM - ROA
2 stops10h 13mUnited Airlines
Tue 11/186:20 amROA - MEM
2 stops9h 25mUnited Airlines
Deal found 10/30$450
This United Airlines deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/315:05 pmJAN - ROA
2 stops24h 38mUnited Airlines
Sun 11/25:20 amROA - JAN
2 stops8h 02mUnited Airlines
Deal found 10/30$1,020
This American Airlines deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/319:13 amJAN - ROA
2 stops10h 16mAmerican Airlines
Sun 11/25:30 amROA - JAN
1 stop7h 01mAmerican Airlines
Deal found 10/30$1,281

Cheap flight deals from Mississippi to Roanoke

Keep the following information in mind while searching for Mississippi to Roanoke flight deals. Data was last updated October 30, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$249
(Delta)

Popular in

October

Cheapest in

May

Average price

$678
Provider with most accurate pricing for Jackson-Evers Intl-Roanoke flight deals.
Search Deals
Provider most trusted by Cheapflights users for Jackson-Evers Intl-Roanoke flights.
Search Deals
From Mississippi to Roanoke
Search Deals
Highest demand for flights based on searches. 32% potential increase in price ($170 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 11% potential price decrease ($37 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in October 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Mississippi to Roanoke that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 30, 2025.
Use the filters below to find and compare flights from Mississippi to Roanoke that are best for you.

Fly from

Mississippi

Fly to

Roanoke

Route

Depart

Return

Price

MemphisRoanoke

MEM - ROA

MEMROA

Memphis

Wed 2/18

9:40 am-2:39 pm

1 stop3h 59m

Roanoke

Sat 2/21

9:00 am-1:42 pm

1 stop5h 42m

$249

MemphisRoanoke

MEM - ROA

MEMROA

Memphis

Fri 11/14

4:33 pm-12:15 am

1 stop6h 42m

Roanoke

Tue 11/18

7:59 pm-11:04 pm

1 stop4h 05m

$279

MemphisRoanoke

MEM - ROA

MEMROA

Memphis

Fri 11/14

3:41 pm-11:53 pm

1 stop7h 12m

Roanoke

Tue 11/18

8:25 am-3:25 pm

2 stops8h 00m

$284

JacksonRoanoke

JAN - ROA

JANROA

Jackson-Evers Intl

Wed 2/18

5:45 am-10:33 am

1 stop3h 48m

Roanoke

Sat 2/21

7:50 pm-11:23 pm

1 stop4h 33m

$284

MemphisRoanoke

MEM - ROA

MEMROA

Memphis

Wed 2/18

6:44 am-5:36 pm

2 stops9h 52m

Roanoke

Sat 2/21

6:00 am-10:25 am

1 stop5h 25m

$324

JacksonRoanoke

JAN - ROA

JANROA

Jackson-Evers Intl

Wed 2/18

7:00 am-8:29 pm

2 stops12h 29m

Roanoke

Sat 2/21

2:51 pm-6:19 pm

1 stop4h 28m

$324

MemphisRoanoke

MEM - ROA

MEMROA

Memphis

Wed 11/19

10:30 am-4:56 pm

1 stop5h 26m

Roanoke

Sun 11/23

5:38 pm-9:58 pm

1 stop5h 20m

$364

MemphisRoanoke

MEM - ROA

MEMROA

Memphis

Thu 11/13

10:30 am-4:56 pm

1 stop5h 26m

Roanoke

Mon 11/17

5:38 pm-9:58 pm

1 stop5h 20m

$433

MemphisRoanoke

MEM - ROA

MEMROA

Memphis

Fri 11/14

7:30 am-6:43 pm

2 stops10h 13m

Roanoke

Tue 11/18

6:20 am-2:45 pm

2 stops9h 25m

$450

JacksonRoanoke

JAN - ROA

JANROA

Jackson-Evers Intl

Wed 2/18

2:03 pm-2:12 pm

2 stops23h 09m

Roanoke

Sat 2/21

6:45 am-9:59 pm

2 stops16h 14m

$617

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/30

Showing 1-10 of 11 results
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Best time to book a flight from Mississippi to Roanoke

Have a flexible travel schedule? Discover the best time to fly to Roanoke from Mississippi with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Mississippi to Roanoke

What is the cheapest month to book a flight from Mississippi to Roanoke?

Currently, May is the cheapest month in which you can book a flight from Mississippi to Roanoke (average of $149). Flying from Mississippi to Roanoke in April is currently the most expensive (average of $435). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MS to ROA?

Find hourly flight availability from Mississippi to Roanoke. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 30, 2025.

It’s optimal to fly from Mississippi to Roanoke in the evening. By choosing this option you can save up to 27% on the cost of your flight, compared to a flight in the morning.

How much does it cost to fly round-trip from Mississippi to Roanoke?

Related info for your journey

Find useful and relevant information for your journey from Mississippi to Roanoke. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Roanoke from Mississippi?

    Roanoke (ROA), located 4.2 mi from the city center, is the airport you fly into when you book flights from Mississippi to Roanoke.

  • How long is the flight from Mississippi to Roanoke?

    Delta, American Airlines, and United Airlines can get you from Mississippi to Roanoke in just under 3h 59m. Your travel time can differ by up to 19h 10m. Airlines will cover a distance of 579 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • Can I find deals for flights from Mississippi to Roanoke that include hotel bookings?

    Yes. In addition to deals on Mississippi to Roanoke flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Mississippi to Roanoke?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Mississippi to Roanoke.

  • Can I find deals for business class flights from Mississippi to Roanoke?

    Yes. Cheapflights offers flight deals from Mississippi to Roanoke by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Mississippi to Roanoke?

    Currently, May is the cheapest month in which you can book a flight from Mississippi to Roanoke (average of $149). Flying from Mississippi to Roanoke in April is currently the most expensive (average of $435). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Roanoke?

Book flights to Roanoke if you plan to visit one of these locations
Radford
Salem
Blacksburg
Christiansburg

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