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Roanoke

$202+ Cheap flights from Mississippi to Roanoke (ROA)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/30. Fares are subject to change and may not be available on all flights or dates of travel.
JAN — ROA
Oct 17 — Oct 241
Fri 10/17
Fri 10/24
1 adult, Economy
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Cheap flight deals from Mississippi to Roanoke

Keep the following information in mind while searching for Mississippi to Roanoke flight deals. Data was last updated September 17, 2025.

Round-trip from

$249
(Delta)

One-way from

$202
(Kiwi.com)

Popular in

October

Cheapest in

January

Average price

$448
From Mississippi to Roanoke
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One-way flight from Mississippi to Roanoke
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Highest demand for flights based on searches. 15% potential increase in price ($61 potential increase over avg. RT price).
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Cheapest flight prices on average. 5% potential price decrease ($17 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from Mississippi to Roanoke

Cheapest flights from Mississippi to Roanoke
Explore the most affordable flight options available from Mississippi to Roanoke. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 17, 2025.

This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/302:48 pmMEM - ROA
1 stop5h 53mUnited Airlines
Sat 10/46:45 amROA - MEM
1 stop5h 11mUnited Airlines
Deal found 9/15$259
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/177:18 pmJAN - ROA
1 stop3h 51mDelta
Tue 10/217:59 pmROA - JAN
1 stop3h 51mDelta
Deal found 9/15$274
This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/257:30 amMEM - ROA
2 stops10h 15mUnited Airlines
Mon 9/295:40 pmROA - MEM
1 stop5h 08mUnited Airlines
Deal found 9/15$289
This Delta deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/243:00 pmJAN - ROA
1 stop4h 37mDelta
Tue 12/306:57 pmROA - JAN
1 stop5h 19mDelta
Deal found 9/16$308
This Delta deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/117:21 pmMEM - ROA
1 stop3h 59mDelta
Sat 12/138:00 pmROA - MEM
1 stop4h 20mDelta
Deal found 9/16$362
This American Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/116:23 amMEM - ROA
1 stop5h 03mAmerican Airlines
Sat 12/138:12 amROA - MEM
2 stops6h 45mAmerican Airlines
Deal found 9/16$367
This Delta deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/35:58 pmJAN - ROA
1 stop5h 11mDelta
Tue 11/46:00 amROA - JAN
1 stop4h 14mDelta
Deal found 9/16$398
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/245:46 pmJAN - ROA
1 stop4h 19mAmerican Airlines
Tue 10/283:05 pmROA - JAN
2 stops9h 05mAmerican Airlines
Deal found 9/15$424
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/176:43 pmJAN - ROA
1 stop4h 16mAmerican Airlines
Tue 10/213:05 pmROA - JAN
2 stops9h 05mAmerican Airlines
Deal found 9/15$444
This Delta deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/243:00 pmJAN - ROA
1 stop4h 37mDelta
Mon 12/296:57 pmROA - JAN
1 stop5h 19mDelta
Deal found 9/16$459
This Delta deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/25:32 amJAN - ROA
1 stop4h 01mDelta
Tue 11/46:00 amROA - JAN
1 stop4h 14mDelta
Deal found 9/16$464
This American Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/187:04 amMEM - ROA
1 stop15h 35mAmerican Airlines
Sat 12/207:36 amROA - MEM
1 stop4h 58mAmerican Airlines
Deal found 9/17$470

Cheapflights Fare Finder

 
Customize your flight search to find flights from Mississippi to Roanoke that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 17, 2025.
Use the filters below to find and compare flights from Mississippi to Roanoke that are best for you.

Fly from

Mississippi

Fly to

Roanoke

Route

Depart

Return

Price

JacksonRoanoke

JAN - ROA

JANROA

Jackson-Evers Intl

Wed 2/18

9:15 am-2:39 pm

1 stop4h 24m

Roanoke

Sat 2/21

7:50 pm-11:23 pm

1 stop4h 33m

$249

MemphisRoanoke

MEM - ROA

MEMROA

Memphis

Tue 9/30

2:48 pm-9:41 pm

1 stop5h 53m

Roanoke

Sat 10/4

6:45 am-10:56 am

1 stop5h 11m

$259

JacksonRoanoke

JAN - ROA

JANROA

Jackson-Evers Intl

Wed 2/18

5:25 am-4:25 pm

2 stops10h 00m

Roanoke

Sat 2/21

7:03 am-10:17 am

1 stop4h 14m

$274

JacksonRoanoke

JAN - ROA

JANROA

Jackson-Evers Intl

Fri 10/17

7:18 pm-12:09 am

1 stop3h 51m

Roanoke

Tue 10/21

7:59 pm-10:50 pm

1 stop3h 51m

$274

JacksonRoanoke

JAN - ROA

JANROA

Jackson-Evers Intl

Fri 10/24

7:18 pm-12:09 am

1 stop3h 51m

Roanoke

Tue 10/28

7:59 pm-10:50 pm

1 stop3h 51m

$274

MemphisRoanoke

MEM - ROA

MEMROA

Memphis

Thu 9/25

7:30 am-6:45 pm

2 stops10h 15m

Roanoke

Mon 9/29

5:40 pm-9:48 pm

1 stop5h 08m

$289

MemphisRoanoke

MEM - ROA

MEMROA

Memphis

Thu 12/11

7:21 pm-12:20 am

1 stop3h 59m

Roanoke

Sat 12/13

8:00 pm-11:20 pm

1 stop4h 20m

$362

MemphisRoanoke

MEM - ROA

MEMROA

Memphis

Thu 12/11

6:23 am-12:26 pm

1 stop5h 03m

Roanoke

Sat 12/13

8:12 am-1:57 pm

2 stops6h 45m

$367

JacksonRoanoke

JAN - ROA

JANROA

Jackson-Evers Intl

Mon 11/3

5:58 pm-12:09 am

1 stop5h 11m

Roanoke

Tue 11/4

6:00 am-9:14 am

1 stop4h 14m

$398

MemphisRoanoke

MEM - ROA

MEMROA

Memphis

Mon 10/6

2:48 pm-9:41 pm

1 stop5h 53m

Roanoke

Fri 10/10

5:40 pm-2:45 pm

1 stop22h 05m

$522

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/15

Showing 1-10 of 20 results
1
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Best time to book a flight from Mississippi to Roanoke

Have a flexible travel schedule? Discover the best time to fly to Roanoke from Mississippi with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Mississippi to Roanoke

What is the cheapest month to book a flight from Mississippi to Roanoke?

Currently, January is the cheapest month in which you can book a flight from Mississippi to Roanoke (average of $338). Flying from Mississippi to Roanoke in December is currently the most expensive (average of $475). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MS to ROA?

Find hourly flight availability from Mississippi to Roanoke. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 17, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Mississippi to Roanoke as you normally would.

Related info for your journey

Find useful and relevant information for your journey from Mississippi to Roanoke. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Roanoke from Mississippi?

    Roanoke (ROA), located 4.2 mi from the city center, is the airport you fly into when you book flights from Mississippi to Roanoke.

  • How long is the flight from Mississippi to Roanoke?

    Delta and United Airlines can get you from Mississippi to Roanoke in just under 4h 24m. Your travel time can differ by up to 1h 29m. Airlines will cover a distance of 669 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines to fly from Mississippi to Roanoke one-way?

    One-way options have recently been found by users for as low as $202 on Allegiant Air. Other airlines that offer cheap prices include United Airlines from $239 and American Airlines from $239 one-way.

  • Can I find deals for flights from Mississippi to Roanoke that include hotel bookings?

    Yes. In addition to deals on Mississippi to Roanoke flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Mississippi to Roanoke?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Mississippi to Roanoke.

  • Can I find deals for business class flights from Mississippi to Roanoke?

    Yes. Cheapflights offers flight deals from Mississippi to Roanoke by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Mississippi to Roanoke?

    Currently, January is the cheapest month in which you can book a flight from Mississippi to Roanoke (average of $338). Flying from Mississippi to Roanoke in December is currently the most expensive (average of $475). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Roanoke?

Book flights to Roanoke if you plan to visit one of these locations
Radford
Salem
Blacksburg
Christiansburg

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