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Roanoke

$109+ Cheap flights from Mississippi to Roanoke (ROA)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/11. Fares are subject to change and may not be available on all flights or dates of travel.
JAN — ROA
Aug 19 — Aug 261
Tue 8/19
Tue 8/26
1 adult, Economy
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Cheap flight deals from Mississippi to Roanoke

Keep the following information in mind while searching for Mississippi to Roanoke flight deals. Data was last updated August 14, 2025.

Round-trip from

$249
(Delta)

One-way from

$109
(Kiwi.com)

Popular in

October

Cheapest in

January

Average price

$253
From Mississippi to Roanoke
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One-way flight from Mississippi to Roanoke
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Highest demand for flights based on searches. 26% potential increase in price ($123 potential increase over avg. RT price).
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Cheapest flight prices on average. 12% potential price decrease ($38 potential savings vs. average RT price).
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Average for round-trip flights in August 2025
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Find flight deals from Mississippi to Roanoke

Cheapest flights from Mississippi to Roanoke
Explore the most affordable flight options available from Mississippi to Roanoke. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 14, 2025.

This Delta deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/76:06 pmMEM - ROA
1 stop5h 03mDelta
Mon 11/107:50 pmROA - MEM
1 stop4h 00mDelta
Deal found 8/14$249
This American Airlines deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/11:38 pmJAN - ROA
1 stop5h 05mAmerican Airlines
Wed 10/156:00 amROA - JAN
1 stop4h 32mAmerican Airlines
Deal found 8/13$274
This American Airlines deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/11:38 pmJAN - ROA
1 stop5h 05mAmerican Airlines
Thu 10/165:00 amROA - JAN
1 stop6h 36mAmerican Airlines
Deal found 8/13$314
This United Airlines deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/272:50 pmMEM - ROA
1 stop5h 29mUnited Airlines
Sun 8/316:20 amROA - MEM
2 stops9h 30mUnited Airlines
Deal found 8/12$359
This American Airlines deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/285:00 amMEM - ROA
1 stop4h 42mAmerican Airlines
Mon 9/15:00 amROA - MEM
1 stop4h 18mAmerican Airlines
Deal found 8/13$382
This United Airlines deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/76:55 pmMEM - ROA
2 stops18h 17mUnited Airlines
Mon 11/105:38 pmROA - MEM
1 stop5h 20mUnited Airlines
Deal found 8/14$454
This American Airlines deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/235:16 amMEM - ROA
1 stop4h 15mAmerican Airlines
Sat 11/296:30 amROA - MEM
1 stop4h 42mAmerican Airlines
Deal found 8/12$458
This American Airlines deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/285:04 amMEM - ROA
1 stop4h 43mAmerican Airlines
Tue 9/305:18 pmROA - MEM
1 stop6h 41mAmerican Airlines
Deal found 8/12$477
This United Airlines deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/47:39 amMEM - ROA
2 stops10h 17mUnited Airlines
Sun 12/710:20 amROA - MEM
2 stops12h 39mUnited Airlines
Deal found 8/12$503
This United Airlines deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/107:00 amJAN - ROA
2 stops15h 24mUnited Airlines
Wed 9/176:20 amROA - JAN
2 stops16h 34mUnited Airlines
Deal found 8/13$517
This American Airlines deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/223:41 pmMEM - ROA
1 stop7h 18mAmerican Airlines
Sat 11/296:30 amROA - MEM
1 stop4h 42mAmerican Airlines
Deal found 8/12$531
This United Airlines deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/19:05 amJAN - ROA
2 stops27h 59mUnited Airlines
Wed 10/157:30 pmROA - JAN
2 stops27h 28mUnited Airlines
Deal found 8/13$564

Cheapflights Fare Finder

 
Customize your flight search to find flights from Mississippi to Roanoke that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 14, 2025.
Use the filters below to find and compare flights from Mississippi to Roanoke that are best for you.

Fly from

Mississippi

Fly to

Roanoke

Route

Depart

Return

Price

MemphisRoanoke

MEM - ROA

MEMROA

Memphis

Fri 11/7

6:06 pm-12:09 am

1 stop5h 03m

Roanoke

Mon 11/10

7:50 pm-10:50 pm

1 stop4h 00m

$249

JacksonRoanoke

JAN - ROA

JANROA

Jackson-Evers Intl

Wed 10/1

1:38 pm-6:37 pm

1 stop3h 59m

Roanoke

Wed 10/15

6:00 am-9:32 am

1 stop4h 32m

$274

JacksonRoanoke

JAN - ROA

JANROA

Jackson-Evers Intl

Wed 10/1

1:38 pm-7:43 pm

1 stop5h 05m

Roanoke

Thu 10/16

5:00 am-10:36 am

1 stop6h 36m

$314

MemphisRoanoke

MEM - ROA

MEMROA

Memphis

Wed 8/27

2:50 pm-9:19 pm

1 stop5h 29m

Roanoke

Sun 8/31

6:20 am-2:50 pm

2 stops9h 30m

$359

MemphisRoanoke

MEM - ROA

MEMROA

Memphis

Thu 8/28

5:00 am-10:42 am

1 stop4h 42m

Roanoke

Mon 9/1

5:00 am-8:18 am

1 stop4h 18m

$382

MemphisRoanoke

MEM - ROA

MEMROA

Memphis

Fri 11/7

6:55 pm-2:12 pm

2 stops18h 17m

Roanoke

Mon 11/10

5:38 pm-9:58 pm

1 stop5h 20m

$454

MemphisRoanoke

MEM - ROA

MEMROA

Memphis

Sun 11/23

5:16 am-10:31 am

1 stop4h 15m

Roanoke

Sat 11/29

6:30 am-10:12 am

1 stop4h 42m

$458

MemphisRoanoke

MEM - ROA

MEMROA

Memphis

Sun 9/28

5:04 am-10:47 am

1 stop4h 43m

Roanoke

Tue 9/30

5:18 pm-10:59 pm

1 stop6h 41m

$477

JacksonRoanoke

JAN - ROA

JANROA

Jackson-Evers Intl

Wed 9/10

7:00 am-11:24 pm

2 stops15h 24m

Roanoke

Wed 9/17

6:20 am-9:54 pm

2 stops16h 34m

$517

JacksonRoanoke

JAN - ROA

JANROA

Jackson-Evers Intl

Wed 10/1

9:05 am-2:04 pm

2 stops27h 59m

Roanoke

Wed 10/15

7:30 pm-9:58 pm

2 stops27h 28m

$564

Flights are sorted by cheapest round-trip flights first.

Deals found on 8/11

Showing 1-10 of 23 results
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Best time to book a flight from Mississippi to Roanoke

Have a flexible travel schedule? Discover the best time to fly to Roanoke from Mississippi with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Mississippi to Roanoke

What is the cheapest month to book a flight from Mississippi to Roanoke?

Currently, January is the cheapest month in which you can book a flight from Mississippi to Roanoke (average of $338). Flying from Mississippi to Roanoke in December is currently the most expensive (average of $474). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MS to ROA?

Find hourly flight availability from Mississippi to Roanoke. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated August 14, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Mississippi to Roanoke as you normally would.

Related info for your journey

Find useful and relevant information for your journey from Mississippi to Roanoke. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Roanoke from Mississippi?

    Roanoke (ROA), located 4.2 mi from the city center, is the airport you fly into when you book flights from Mississippi to Roanoke.

  • What are the cheapest airlines to fly from Mississippi to Roanoke one-way?

    One-way options have recently been found by users for as low as $199 on Allegiant Air. Other airlines that offer cheap prices include Delta from $345 and United Airlines from $375 one-way.

  • Can I find deals for flights from Mississippi to Roanoke that include hotel bookings?

    Yes. In addition to deals on Mississippi to Roanoke flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Mississippi to Roanoke?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Mississippi to Roanoke.

  • Can I find deals for business class flights from Mississippi to Roanoke?

    Yes. Cheapflights offers flight deals from Mississippi to Roanoke by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Mississippi to Roanoke?

    Currently, January is the cheapest month in which you can book a flight from Mississippi to Roanoke (average of $338). Flying from Mississippi to Roanoke in December is currently the most expensive (average of $474). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Roanoke?

Book flights to Roanoke if you plan to visit one of these locations
Radford
Salem
Blacksburg
Christiansburg

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Alternative routes for Mississippi to Roanoke

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Top airline flying from Mississippi to Roanoke

Discover the top airline that operate flights from Mississippi to Roanoke. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 14, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$248Average$367FlexibilityNo cancel feeOn-time71%

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