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Roanoke

$259+ Cheap flights from Des Moines to Roanoke (DSM - ROA)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/29. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — ROA
Aug 19 — Aug 261
Tue 8/19
Tue 8/26
1 adult, Economy
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Cheap flight deals from Des Moines to Roanoke

Discover tips and strategies to find the most affordable flight options for your journey from Des Moines (DSM) to Roanoke (ROA). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated August 14, 2025.

Round-trip from

$259
(American Airlines)

Popular in

January

Cheapest in

August

Average price

$258
From Des Moines to Roanoke
Search Deals
Highest demand for flights based on searches. 32% potential increase in price ($188 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 8% potential price decrease ($31 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in August 2025
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Find flight deals from Des Moines to Roanoke

Cheapest flights from Des Moines to Roanoke
Explore the most affordable flight options available from Des Moines to Roanoke. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 14, 2025.

This Delta deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/293:12 pmDSM - ROA
1 stop7h 06mDelta
Tue 9/27:10 amROA - DSM
1 stop8h 22mDelta
Deal found 8/14$259
This United Airlines deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/293:25 pmDSM - ROA
1 stop4h 54mUnited Airlines
Tue 9/26:20 amROA - DSM
2 stops7h 03mUnited Airlines
Deal found 8/14$264
This Delta deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/235:12 pmDSM - ROA
1 stop6h 20mDelta
Tue 8/267:10 amROA - DSM
1 stop8h 22mDelta
Deal found 8/12$284
This United Airlines deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/3011:35 amDSM - ROA
1 stop4h 29mUnited Airlines
Mon 9/16:45 amROA - DSM
1 stop6h 38mUnited Airlines
Deal found 8/13$319
This American Airlines deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/146:12 pmDSM - ROA
1 stop4h 47mAmerican Airlines
Wed 8/203:14 pmROA - DSM
1 stop7h 31mAmerican Airlines
Deal found 8/13$324
This United Airlines deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/293:25 pmDSM - ROA
1 stop4h 54mUnited Airlines
Sun 8/316:20 amROA - DSM
2 stops10h 53mUnited Airlines
Deal found 8/14$334
This United Airlines deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/273:25 pmDSM - ROA
1 stop5h 16mUnited Airlines
Sat 10/46:45 amROA - DSM
1 stop6h 26mUnited Airlines
Deal found 8/13$344
This Delta deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/203:12 pmDSM - ROA
1 stop7h 06mDelta
Sat 8/236:00 amROA - DSM
1 stop5h 38mDelta
Deal found 8/13$354

Cheapflights Fare Finder

 
Customize your flight search to find flights from Des Moines to Roanoke that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 14, 2025.
Use the filters below to find and compare flights from Des Moines to Roanoke that are best for you.

Fly from

Des Moines

Fly to

Roanoke

Route

Depart

Return

Price

Des MoinesRoanoke

DSM - ROA

DSMROA

Des Moines

Fri 8/29

6:12 pm-11:52 pm

1 stop4h 40m

Roanoke

Sun 8/31

6:40 am-10:53 am

1 stop5h 13m

$259

Des MoinesRoanoke

DSM - ROA

DSMROA

Des Moines

Fri 8/29

3:12 pm-11:18 pm

1 stop7h 06m

Roanoke

Tue 9/2

7:10 am-2:32 pm

1 stop8h 22m

$259

Des MoinesRoanoke

DSM - ROA

DSMROA

Des Moines

Sat 8/30

3:25 pm-11:24 pm

2 stops6h 59m

Roanoke

Mon 9/1

6:45 am-12:23 pm

1 stop6h 38m

$264

Des MoinesRoanoke

DSM - ROA

DSMROA

Des Moines

Fri 8/29

3:25 pm-9:19 pm

1 stop4h 54m

Roanoke

Tue 9/2

6:20 am-12:23 pm

2 stops7h 03m

$264

Des MoinesRoanoke

DSM - ROA

DSMROA

Des Moines

Fri 8/29

3:25 pm-9:19 pm

1 stop4h 54m

Roanoke

Sun 8/31

6:20 am-4:13 pm

2 stops10h 53m

$334

Des MoinesRoanoke

DSM - ROA

DSMROA

Des Moines

Sat 9/27

3:25 pm-9:41 pm

1 stop5h 16m

Roanoke

Sat 10/4

6:45 am-12:11 pm

1 stop6h 26m

$344

Des MoinesRoanoke

DSM - ROA

DSMROA

Des Moines

Thu 8/28

6:15 am-6:44 pm

2 stops11h 29m

Roanoke

Mon 9/1

6:45 am-10:39 am

1 stop4h 54m

$374

Flights are sorted by cheapest round-trip flights first.

Deals found on 8/14

Best time to book a flight from Des Moines to Roanoke

Have a flexible travel schedule? Discover the best time to fly to Roanoke from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to Roanoke

What is the cheapest month to book a flight from Des Moines to Roanoke?

Currently, January is the cheapest month in which you can book a flight from Des Moines to Roanoke (average of $338). Flying from Des Moines to Roanoke in December is currently the most expensive (average of $474). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Des Moines to Roanoke?

Reviews of airlines servicing Roanoke

Get insights into the airlines that provide service to Roanoke. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Roanoke. Reviews last updated August 14, 2025.
Read through reviews of airlines operating flights from Des Moines to Roanoke, such as Delta and American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,980 reviews

Crew

8.5

Entertainment

7.9

Food

7.3

Boarding

8.2

Comfort

7.9

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,980 reviews
Delta
8.0
Very good
7,980 reviews

Crew

8.5

Entertainment

7.9

Food

7.3

Boarding

8.2

Comfort

7.9

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,980 reviews

Crew

8.5

Entertainment

7.9

Food

7.3

Boarding

8.2

Comfort

7.9

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Roanoke. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines flying from Des Moines to Roanoke round-trip?

    Our cheapest airline available from Des Moines to Roanoke is American Airlines. Our recent data shows that you can find tickets from as low as $248 on this airline. An additional option worth looking into is Delta, starting at $248. American Airlines is currently priced 37% below the average price you’ll pay for this route.

  • Can I find deals for flights from Des Moines to Roanoke that include hotel bookings?

    Yes. In addition to deals on Des Moines to Roanoke flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to Roanoke?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Roanoke.

  • Can I find deals for business class flights from Des Moines to Roanoke?

    Yes. Cheapflights offers flight deals from Des Moines to Roanoke by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Des Moines to Roanoke?

    Currently, January is the cheapest month in which you can book a flight from Des Moines to Roanoke (average of $338). Flying from Des Moines to Roanoke in December is currently the most expensive (average of $474). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Roanoke?

Book flights to Roanoke if you plan to visit one of these locations
Radford
Salem
Blacksburg
Christiansburg

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Alternative routes for Des Moines to Roanoke

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Top 2 airlines flying from Des Moines to Roanoke

Discover the top 2 airlines that operate flights from Des Moines to Roanoke. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 14, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$248Average$335FlexibilityNo cancel feeOn-time71%
DeltaCheapest$248Average$338FlexibilityNo cancel feeOn-timeN/A

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