HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Roanoke

$269+ Cheap flights from Des Moines to Roanoke (DSM - ROA)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/27. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — ROA
Jan 31 — Feb 71
Sat 1/31
Sat 2/7
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Des Moines to Roanoke with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Des Moines to Roanoke

Best flights from Des Moines to Roanoke
Discover carefully curated flight deals from Des Moines to Roanoke that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated January 1, 2026.

This Delta deal was found by Cheapflights users on 1/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/276:30 pmDSM - ROA
1 stop4h 19mDelta
Tue 6/306:00 amROA - DSM
1 stop5h 14mDelta
Deal found 1/1$269
This United Airlines deal was found by Cheapflights users on 1/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/293:15 pmDSM - ROA
2 stops7h 08mUnited Airlines
Sat 7/43:00 pmROA - DSM
2 stops9h 39mUnited Airlines
Deal found 1/1$350
This Delta deal was found by Cheapflights users on 1/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/296:30 pmDSM - ROA
1 stop4h 19mDelta
Sat 7/46:00 amROA - DSM
1 stop5h 14mDelta
Deal found 1/1$269
This Delta deal was found by Cheapflights users on 1/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/306:30 pmDSM - ROA
1 stop4h 19mDelta
Sat 7/46:00 amROA - DSM
1 stop5h 14mDelta
Deal found 1/1$269
This Delta deal was found by Cheapflights users on 1/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/276:30 pmDSM - ROA
1 stop4h 19mDelta
Fri 7/36:00 amROA - DSM
1 stop5h 14mDelta
Deal found 1/1$304
This Delta deal was found by Cheapflights users on 1/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/135:15 pmDSM - ROA
1 stop5h 51mDelta
Wed 2/1811:20 amROA - DSM
2 stops10h 29mDelta
Deal found 1/1$309
This Delta deal was found by Cheapflights users on 1/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/266:30 pmDSM - ROA
1 stop4h 19mDelta
Sat 7/47:50 pmROA - DSM
2 stops19h 17mDelta
Deal found 1/1$388
This Delta deal was found by Cheapflights users on 1/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/276:30 pmDSM - ROA
1 stop4h 19mDelta
Sat 7/47:50 pmROA - DSM
2 stops19h 17mDelta
Deal found 1/1$388
This Delta deal was found by Cheapflights users on 1/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/266:30 pmDSM - ROA
1 stop4h 19mDelta
Tue 6/307:50 pmROA - DSM
2 stops15h 25mDelta
Deal found 1/1$388
This Delta deal was found by Cheapflights users on 1/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/165:16 pmDSM - ROA
1 stop5h 48mDelta
Tue 1/206:00 amROA - DSM
1 stop5h 41mDelta
Deal found 1/1$389

Find flight deals from Des Moines to Roanoke

Discover tips and strategies to find the most affordable flight options for your journey from Des Moines (DSM) to Roanoke (ROA). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated January 1, 2026.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$269
(American Airlines)

Popular in

December

Cheapest in

August

Average price

$688
Provider with most accurate pricing for Des Moines-Roanoke flight deals.
Search Deals
Provider most trusted by Cheapflights users for Des Moines-Roanoke flights.
Search Deals
From Des Moines to Roanoke
Search Deals
Highest demand for flights based on searches. 27% potential increase in price ($163 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 8% potential price decrease ($33 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in January 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Des Moines to Roanoke that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 1, 2026.
Use the filters below to find and compare flights from Des Moines to Roanoke that are best for you.

Fly from

Des Moines

Fly to

Roanoke

Route

Depart

Return

Price

Des MoinesRoanoke

DSM - ROA

DSMROA

Des Moines

Sat 6/27

6:30 pm-11:49 pm

1 stop4h 19m

Roanoke

Tue 6/30

6:00 am-10:14 am

1 stop5h 14m

$269

Des MoinesRoanoke

DSM - ROA

DSMROA

Des Moines

Mon 6/29

6:30 pm-11:49 pm

1 stop4h 19m

Roanoke

Sat 7/4

6:00 am-10:14 am

1 stop5h 14m

$269

Des MoinesRoanoke

DSM - ROA

DSMROA

Des Moines

Tue 6/30

6:30 pm-11:49 pm

1 stop4h 19m

Roanoke

Sat 7/4

6:00 am-10:14 am

1 stop5h 14m

$269

Des MoinesRoanoke

DSM - ROA

DSMROA

Des Moines

Sat 6/27

6:30 pm-11:49 pm

1 stop4h 19m

Roanoke

Fri 7/3

6:00 am-10:14 am

1 stop5h 14m

$304

Des MoinesRoanoke

DSM - ROA

DSMROA

Des Moines

Fri 2/13

5:15 pm-12:06 am

1 stop5h 51m

Roanoke

Wed 2/18

11:20 am-8:49 pm

2 stops10h 29m

$309

Des MoinesRoanoke

DSM - ROA

DSMROA

Des Moines

Mon 6/29

3:15 pm-11:23 pm

2 stops7h 08m

Roanoke

Sat 7/4

3:00 pm-11:39 pm

2 stops9h 39m

$350

Des MoinesRoanoke

DSM - ROA

DSMROA

Des Moines

Fri 6/26

6:30 pm-11:49 pm

1 stop4h 19m

Roanoke

Sat 7/4

7:50 pm-2:07 pm

2 stops19h 17m

$388

Des MoinesRoanoke

DSM - ROA

DSMROA

Des Moines

Sat 6/27

6:30 pm-11:49 pm

1 stop4h 19m

Roanoke

Sat 7/4

7:50 pm-2:07 pm

2 stops19h 17m

$388

Des MoinesRoanoke

DSM - ROA

DSMROA

Des Moines

Fri 6/26

6:30 pm-11:49 pm

1 stop4h 19m

Roanoke

Tue 6/30

7:50 pm-10:15 am

2 stops15h 25m

$388

Des MoinesRoanoke

DSM - ROA

DSMROA

Des Moines

Fri 1/16

5:16 pm-12:04 am

1 stop5h 48m

Roanoke

Tue 1/20

6:00 am-10:41 am

1 stop5h 41m

$389

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/1

Compare providers for flights from Des Moines to Roanoke

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Des Moines to Roanoke in January.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
eDreamsPrice Accuracy3 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Des Moines-Roanoke flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Des Moines-Roanoke flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Des Moines-Roanoke flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Des Moines-Roanoke flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Des Moines-Roanoke flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Des Moines to Roanoke

Have a flexible travel schedule? Discover the best time to fly to Roanoke from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to Roanoke

What is the cheapest month to book a flight from Des Moines to Roanoke?

Currently, May is the cheapest month in which you can book a flight from Des Moines to Roanoke (average of $248). Flying from Des Moines to Roanoke in December is currently the most expensive (average of $436). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Des Moines to Roanoke?

Reviews of airlines servicing Roanoke

Get insights into the airlines that provide service to Roanoke. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Roanoke. Reviews last updated January 1, 2026.
Read through reviews of airlines operating flights from Des Moines to Roanoke, such as Delta and American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,021 reviews

Entertainment

7.8

Comfort

7.9

Crew

8.5

Food

7.2

Boarding

8.1

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,021 reviews
Delta
7.9
Good
8,021 reviews

Entertainment

7.8

Comfort

7.9

Crew

8.5

Food

7.2

Boarding

8.1

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,075 reviews
Delta
7.9
Good
8,021 reviews

Entertainment

7.8

Comfort

7.9

Crew

8.5

Food

7.2

Boarding

8.1

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Roanoke. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Des Moines to Roanoke?

    Airlines like Delta fly from Des Moines to Roanoke in about 4h 19m. The time it takes to get you to your destination can typically vary by up to . There are 784 mi between Des Moines and Roanoke.

  • What are the cheapest airlines flying from Des Moines to Roanoke round-trip?

    Our cheapest airline available from Des Moines to Roanoke is Delta. Our recent data shows that you can find tickets from as low as $248 on this airline. An additional option worth looking into is American Airlines, starting at $258. Delta is currently priced 42% below the average price you’ll pay for this route.

  • Can I find deals for flights from Des Moines to Roanoke that include hotel bookings?

    Yes. In addition to deals on Des Moines to Roanoke flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to Roanoke?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Roanoke.

  • Can I find deals for business class flights from Des Moines to Roanoke?

    Yes. Cheapflights offers flight deals from Des Moines to Roanoke by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Des Moines to Roanoke?

    Currently, May is the cheapest month in which you can book a flight from Des Moines to Roanoke (average of $248). Flying from Des Moines to Roanoke in December is currently the most expensive (average of $436). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Roanoke?

Book flights to Roanoke if you plan to visit one of these locations
Radford
Salem
Blacksburg
Christiansburg

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Des Moines to Roanoke

See prices for flight routes from nearby airports that may be better suited for you.
Omaha to Dulles Intl flights
Omaha to Reagan-National flights
Des Moines to Reagan-National flights
Des Moines to Dulles Intl flights
Cedar Rapids to Reagan-National flights
Cedar Rapids to Dulles Intl flights
Des Moines to Raleigh flights
Omaha to Norfolk flights
Des Moines to Richmond flights
Omaha to Raleigh flights
Des Moines to Greensboro flights
Cedar Rapids to Raleigh flights
Des Moines to Norfolk flights
Cedar Rapids to Greensboro flights
Moline to Dulles Intl flights
Moline to Raleigh flights
Omaha to Richmond flights
Moline to Reagan-National flights
Moline to Norfolk flights
Cedar Rapids to Charlottesville flights
Cedar Rapids to Norfolk flights
Cedar Rapids to Richmond flights
Cedar Rapids to Blountville flights
Omaha to Newport News flights
Moline to Roanoke flights
Moline to Richmond flights
Cedar Rapids to Roanoke flights
Cedar Rapids to Newport News flights
Omaha to Greensboro flights
Omaha to Charlottesville flights
Sioux City to Charlottesville flights
Moline to Greensboro flights
Sioux City to Dulles Intl flights
Waterloo to Raleigh flights
Des Moines to Charlottesville flights
La Crosse to Raleigh flights
La Crosse to Reagan-National flights
La Crosse to Dulles Intl flights
Moline to Charlottesville flights
Sioux City to Greensboro flights
La Crosse to Norfolk flights
Sioux City to Raleigh flights
Sioux City to Reagan-National flights
Waterloo to Dulles Intl flights
Omaha to Blountville flights
Des Moines to Newport News flights
Omaha to Lynchburg flights
Omaha to Salisbury flights

Top 2 airlines flying from Des Moines to Roanoke

Discover the top 2 airlines that operate flights from Des Moines to Roanoke. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 1, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$248Average$323FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$258Average$363FlexibilityNo cancel feeOn-time71%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.