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Roanoke

$249+ Cheap flights from Des Moines to Roanoke (DSM - ROA)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/7. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — ROA
Nov 1 — Nov 81
Sat 11/1
Sat 11/8
1 adult, Economy
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Cheap flight deals from Des Moines to Roanoke

Discover tips and strategies to find the most affordable flight options for your journey from Des Moines (DSM) to Roanoke (ROA). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 2, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$249
(Delta)

Popular in

January

Cheapest in

August

Average price

$341
Provider with most accurate pricing for Des Moines-Roanoke flight deals.
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Provider most trusted by Cheapflights users for Des Moines-Roanoke flights.
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From Des Moines to Roanoke
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Highest demand for flights based on searches. 31% potential increase in price ($184 potential increase over avg. RT price).
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Cheapest flight prices on average. 8% potential price decrease ($31 potential savings vs. average RT price).
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Average for round-trip flights in October 2025
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Find flight deals from Des Moines to Roanoke

Cheapest flights from Des Moines to Roanoke
Explore the most affordable flight options available from Des Moines to Roanoke. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 2, 2025.

This Delta deal was found by Cheapflights users on 10/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/76:39 pmDSM - ROA
1 stop4h 30mDelta
Mon 11/107:05 amROA - DSM
1 stop8h 32mDelta
Deal found 10/1$249
This American Airlines deal was found by Cheapflights users on 10/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/132:16 pmDSM - ROA
1 stop7h 35mAmerican Airlines
Sun 11/166:30 amROA - DSM
1 stop8h 01mAmerican Airlines
Deal found 10/2$294
This Delta deal was found by Cheapflights users on 10/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/216:32 pmDSM - ROA
1 stop4h 43mDelta
Mon 11/246:00 amROA - DSM
1 stop5h 42mDelta
Deal found 10/1$309
This United Airlines deal was found by Cheapflights users on 10/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/163:25 pmDSM - ROA
1 stop5h 16mUnited Airlines
Tue 10/216:45 amROA - DSM
2 stops10h 32mUnited Airlines
Deal found 10/1$328
This Delta deal was found by Cheapflights users on 10/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/133:17 pmDSM - ROA
1 stop6h 58mDelta
Sun 11/166:00 amROA - DSM
2 stops9h 05mDelta
Deal found 10/1$344
This American Airlines deal was found by Cheapflights users on 10/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/1612:49 pmDSM - ROA
1 stop6h 40mAmerican Airlines
Tue 10/213:05 pmROA - DSM
1 stop7h 08mAmerican Airlines
Deal found 10/1$382
This United Airlines deal was found by Cheapflights users on 10/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/161:00 pmDSM - ROA
1 stop7h 41mUnited Airlines
Mon 10/205:40 pmROA - DSM
1 stop5h 10mUnited Airlines
Deal found 10/2$389

Cheapflights Fare Finder

 
Customize your flight search to find flights from Des Moines to Roanoke that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 2, 2025.
Use the filters below to find and compare flights from Des Moines to Roanoke that are best for you.

Fly from

Des Moines

Fly to

Roanoke

Route

Depart

Return

Price

Des MoinesRoanoke

DSM - ROA

DSMROA

Des Moines

Fri 11/7

6:39 pm-12:09 am

1 stop4h 30m

Roanoke

Mon 11/10

7:05 am-2:37 pm

1 stop8h 32m

$249

Des MoinesRoanoke

DSM - ROA

DSMROA

Des Moines

Thu 11/13

2:16 pm-10:51 pm

1 stop7h 35m

Roanoke

Sun 11/16

6:30 am-1:31 pm

1 stop8h 01m

$294

Des MoinesRoanoke

DSM - ROA

DSMROA

Des Moines

Fri 11/21

6:32 pm-12:15 am

1 stop4h 43m

Roanoke

Mon 11/24

6:00 am-10:42 am

1 stop5h 42m

$309

Des MoinesRoanoke

DSM - ROA

DSMROA

Des Moines

Thu 10/16

3:25 pm-9:41 pm

1 stop5h 16m

Roanoke

Tue 10/21

6:45 am-4:17 pm

2 stops10h 32m

$328

Des MoinesRoanoke

DSM - ROA

DSMROA

Des Moines

Thu 11/13

3:17 pm-11:15 pm

1 stop6h 58m

Roanoke

Sun 11/16

6:00 am-2:05 pm

2 stops9h 05m

$344

Des MoinesRoanoke

DSM - ROA

DSMROA

Des Moines

Thu 10/16

12:49 pm-8:29 pm

1 stop6h 40m

Roanoke

Tue 10/21

3:05 pm-9:13 pm

1 stop7h 08m

$382

Des MoinesRoanoke

DSM - ROA

DSMROA

Des Moines

Thu 10/16

1:00 pm-9:41 pm

1 stop7h 41m

Roanoke

Mon 10/20

5:40 pm-9:50 pm

1 stop5h 10m

$389

Des MoinesRoanoke

DSM - ROA

DSMROA

Des Moines

Tue 3/24

11:30 am-4:56 pm

1 stop4h 26m

Roanoke

Sat 3/28

5:38 pm-9:36 pm

1 stop4h 58m

$392

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/1

Compare providers for flights from Des Moines to Roanoke

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Des Moines to Roanoke in October.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars
eDreamsPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Des Moines-Roanoke flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Des Moines-Roanoke flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Des Moines-Roanoke flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Des Moines-Roanoke flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Des Moines-Roanoke flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Des Moines to Roanoke

Have a flexible travel schedule? Discover the best time to fly to Roanoke from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to Roanoke

What is the cheapest month to book a flight from Des Moines to Roanoke?

Currently, January is the cheapest month in which you can book a flight from Des Moines to Roanoke (average of $338). Flying from Des Moines to Roanoke in December is currently the most expensive (average of $469). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Des Moines to Roanoke?

Reviews of airlines servicing Roanoke

Get insights into the airlines that provide service to Roanoke. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Roanoke. Reviews last updated October 2, 2025.
Read through reviews of airlines operating flights from Des Moines to Roanoke, such as Delta and American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,962 reviews

Boarding

8.2

Comfort

7.9

Food

7.3

Entertainment

7.9

Crew

8.5

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,962 reviews
Delta
8.0
Very good
7,962 reviews

Boarding

8.2

Comfort

7.9

Food

7.3

Entertainment

7.9

Crew

8.5

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
American Airlines
7.2
Good
11,033 reviews
Delta
8.0
Very good
7,962 reviews

Boarding

8.2

Comfort

7.9

Food

7.3

Entertainment

7.9

Crew

8.5

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Roanoke. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Des Moines to Roanoke?

    Airlines like Delta, American Airlines, and United Airlines fly from Des Moines to Roanoke in about 4h 30m. The time it takes to get you to your destination can typically vary by up to 3h 05m. There are 784 mi between Des Moines and Roanoke. This flight may include one or multiple stops.

  • What are the cheapest airlines flying from Des Moines to Roanoke round-trip?

    Our cheapest airline available from Des Moines to Roanoke is American Airlines. Our recent data shows that you can find tickets from as low as $248 on this airline. An additional option worth looking into is Delta, starting at $248. American Airlines is currently priced 38% below the average price you’ll pay for this route.

  • Can I find deals for flights from Des Moines to Roanoke that include hotel bookings?

    Yes. In addition to deals on Des Moines to Roanoke flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to Roanoke?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Roanoke.

  • Can I find deals for business class flights from Des Moines to Roanoke?

    Yes. Cheapflights offers flight deals from Des Moines to Roanoke by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Des Moines to Roanoke?

    Currently, January is the cheapest month in which you can book a flight from Des Moines to Roanoke (average of $338). Flying from Des Moines to Roanoke in December is currently the most expensive (average of $469). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Roanoke?

Book flights to Roanoke if you plan to visit one of these locations
Radford
Salem
Blacksburg
Christiansburg

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Alternative routes for Des Moines to Roanoke

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Top 2 airlines flying from Des Moines to Roanoke

Discover the top 2 airlines that operate flights from Des Moines to Roanoke. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 2, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$248Average$336FlexibilityNo cancel feeOn-time71%
DeltaCheapest$248Average$323FlexibilityNo cancel feeOn-timeN/A

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