$179+ Cheap flights from Des Moines to Reno (DSM - RNO)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/2. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — RNO
Mar 27 — Apr 31
1 adult, Economy
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Find cheap flights from Des Moines to Reno with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Des Moines to Reno
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Best
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Cheapest flights from Des Moines to RenoExplore the most affordable flight options available from Des Moines to Reno. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 25, 2026.
Explore the most affordable flight options available from Des Moines to Reno. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 25, 2026.
This Kiwi.com deal was found by Cheapflights users on 2/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/3110:26 pm
DSM
- RNO
1 stop14h 26m
Multiple Airlines
Wed 6/38:55 pm
RNO
- DSM
1 stop21h 46m
Multiple Airlines
Deal found 2/22![Multiple Airlines logo]()
$244
This Kiwi.com deal was found by Cheapflights users on 2/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/252:50 pm
DSM
- RNO
2 stops46h 02m
Multiple Airlines
Wed 6/38:55 pm
RNO
- DSM
1 stop21h 46m
Multiple Airlines
Deal found 2/22![Multiple Airlines logo]()
$252
This Kiwi.com deal was found by Cheapflights users on 2/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/3110:26 pm
DSM
- RNO
1 stop14h 26m
Multiple Airlines
Tue 6/28:52 pm
RNO
- DSM
1 stop14h 03m
Multiple Airlines
Deal found 2/22![Multiple Airlines logo]()
$261
This Kiwi.com deal was found by Cheapflights users on 2/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/3110:26 pm
DSM
- RNO
1 stop23h 34m
Multiple Airlines
Thu 6/411:47 am
RNO
- DSM
1 stop6h 54m
Multiple Airlines
Deal found 2/22![Multiple Airlines logo]()
$264
This Kiwi.com deal was found by Cheapflights users on 2/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/252:50 pm
DSM
- RNO
2 stops46h 02m
Multiple Airlines
Tue 6/28:52 pm
RNO
- DSM
1 stop14h 03m
Multiple Airlines
Deal found 2/22![Multiple Airlines logo]()
$269
This Kiwi.com deal was found by Cheapflights users on 2/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/252:50 pm
DSM
- RNO
2 stops46h 02m
Multiple Airlines
Thu 6/411:47 am
RNO
- DSM
1 stop6h 54m
Multiple Airlines
Deal found 2/22![Multiple Airlines logo]()
$272
This Kiwi.com deal was found by Cheapflights users on 2/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/311:00 am
DSM
- RNO
1 stop28h 49m
Multiple Airlines
Thu 5/72:44 pm
RNO
- DSM
1 stop28h 27m
Multiple Airlines
Deal found 2/22![Multiple Airlines logo]()
$288
This Kiwi.com deal was found by Cheapflights users on 2/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/292:50 pm
DSM
- RNO
2 stops31h 07m
Multiple Airlines
Tue 6/28:52 pm
RNO
- DSM
1 stop14h 03m
Multiple Airlines
Deal found 2/22![Multiple Airlines logo]()
$289
This Kiwi.com deal was found by Cheapflights users on 2/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/289:34 pm
DSM
- RNO
1 stop15h 18m
Multiple Airlines
Wed 6/38:55 pm
RNO
- DSM
1 stop21h 46m
Multiple Airlines
Deal found 2/22![Multiple Airlines logo]()
$290
This Kiwi.com deal was found by Cheapflights users on 2/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/227:30 am
DSM
- RNO
1 stop29h 09m
Multiple Airlines
Sun 3/292:44 pm
RNO
- DSM
2 stops26h 32m
Multiple Airlines
Deal found 2/22![Multiple Airlines logo]()
$292
This Kiwi.com deal was found by Cheapflights users on 2/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/3110:26 pm
DSM
- RNO
1 stop23h 34m
Multiple Airlines
Fri 6/511:47 am
RNO
- DSM
1 stop7h 19m
Multiple Airlines
Deal found 2/22![Multiple Airlines logo]()
$293
Best flights from Des Moines to RenoDiscover carefully curated flight deals from Des Moines to Reno that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated February 25, 2026.
Discover carefully curated flight deals from Des Moines to Reno that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated February 25, 2026.
This Delta deal was found by Cheapflights users on 2/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/182:44 pm
DSM
- RNO
1 stop9h 11m
Delta
Wed 4/2210:34 am
RNO
- DSM
2 stops8h 38m
Delta
Deal found 2/22![Delta logo]()
$342
This United Airlines deal was found by Cheapflights users on 2/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/23:20 pm
DSM
- RNO
1 stop9h 31m
United Airlines
Thu 5/79:16 am
RNO
- DSM
1 stop4h 59m
United Airlines
Deal found 2/23![United Airlines logo]()
$351
This Southwest deal was found by Cheapflights users on 2/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/86:30 pm
DSM
- RNO
1 stop5h 05m
Southwest
Wed 4/1510:55 am
RNO
- DSM
2 stops8h 20m
Southwest
Deal found 2/22![Southwest logo]()
$357
This Kiwi.com deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/87:00 am
DSM
- RNO
2 stops32h 46m
Multiple Airlines
Thu 3/128:38 pm
RNO
- DSM
1 stop23h 56m
Multiple Airlines
Deal found 2/21![Multiple Airlines logo]()
$411
This American Airlines deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/32:38 pm
DSM
- RNO
1 stop5h 49m
American Airlines
Thu 5/79:51 am
RNO
- DSM
1 stop5h 38m
American Airlines
Deal found 2/21![American Airlines logo]()
$427
This Southwest deal was found by Cheapflights users on 2/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/71:55 pm
DSM
- RNO
1 stop11h 45m
Southwest
Mon 5/112:50 pm
RNO
- DSM
1 stop5h 05m
Southwest
Deal found 2/23![Southwest logo]()
$357
This Delta deal was found by Cheapflights users on 2/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/42:44 pm
DSM
- RNO
1 stop9h 11m
Delta
Fri 5/810:50 pm
RNO
- DSM
1 stop10h 18m
Delta
Deal found 2/23![Delta logo]()
$370
This Southwest deal was found by Cheapflights users on 2/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/38:40 pm
DSM
- RNO
1 stop5h 25m
Southwest
Thu 5/75:10 am
RNO
- DSM
1 stop11h 25m
Southwest
Deal found 2/23![Southwest logo]()
$395
This Delta deal was found by Cheapflights users on 2/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/304:25 pm
DSM
- RNO
2 stops9h 10m
Delta
Fri 4/311:10 pm
RNO
- DSM
1 stop9h 38m
Delta
Deal found 2/24![Delta logo]()
$423
Last-minute flights from Des Moines to RenoDiscover last-minute flight deals from Des Moines to Reno. Data last updated February 25, 2026 and is based on user searches.
Discover last-minute flight deals from Des Moines to Reno. Data last updated February 25, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/87:00 am
DSM
- RNO
2 stops32h 46m
Multiple Airlines
Thu 3/128:38 pm
RNO
- DSM
1 stop23h 56m
Multiple Airlines
Deal found 2/21![Multiple Airlines logo]()
$411
This Kiwi.com deal was found by Cheapflights users on 2/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/93:32 pm
DSM
- RNO
1 stop21h 08m
Multiple Airlines
Thu 3/128:38 pm
RNO
- DSM
1 stop23h 56m
Multiple Airlines
Deal found 2/23![Multiple Airlines logo]()
$366
This Kiwi.com deal was found by Cheapflights users on 2/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/208:22 pm
DSM
- RNO
1 stop20h 37m
Multiple Airlines
Mon 3/233:39 pm
RNO
- DSM
2 stops18h 54m
Multiple Airlines
Deal found 2/24![Multiple Airlines logo]()
$539
This Kiwi.com deal was found by Cheapflights users on 2/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/227:30 am
DSM
- RNO
1 stop29h 09m
Multiple Airlines
Sun 3/292:44 pm
RNO
- DSM
2 stops26h 32m
Multiple Airlines
Deal found 2/22![Multiple Airlines logo]()
$292
This Southwest deal was found by Cheapflights users on 2/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/224:40 pm
DSM
- RNO
2 stops10h 00m
Southwest
Sun 3/2912:40 pm
RNO
- DSM
2 stops7h 55m
Southwest
Deal found 2/22![Southwest logo]()
$525
This American Airlines deal was found by Cheapflights users on 2/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/306:33 pm
DSM
- RNO
1 stop6h 16m
American Airlines
Fri 4/311:52 pm
RNO
- DSM
1 stop8h 52m
American Airlines
Deal found 2/24![American Airlines logo]()
$357
This Delta deal was found by Cheapflights users on 2/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/304:25 pm
DSM
- RNO
2 stops9h 10m
Delta
Fri 4/311:10 pm
RNO
- DSM
1 stop9h 38m
Delta
Deal found 2/24![Delta logo]()
$423
One-way flights from Des Moines to RenoSearch for one-way flight options from Des Moines to Reno. Find affordable one-way fares based on user searches. Data last updated February 25, 2026.
Search for one-way flight options from Des Moines to Reno. Find affordable one-way fares based on user searches. Data last updated February 25, 2026.
This American Airlines deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/25:00 am
DSM
- RNO
1 stop6h 25m
American Airlines
Deal found 2/21![American Airlines logo]()
$179
This Southwest deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/22:15 pm
DSM
- RNO
2 stops8h 40m
Southwest
Deal found 2/21![Southwest logo]()
$194
This Kiwi.com deal was found by Cheapflights users on 2/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/27:15 am
DSM
- RNO
2 stops14h 06m
Multiple Airlines
Deal found 2/25![Multiple Airlines logo]()
$264
This American Airlines deal was found by Cheapflights users on 2/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/25:05 am
DSM
- RNO
1 stop7h 27m
American Airlines
Deal found 2/25![American Airlines logo]()
$489
Find flight deals from Des Moines to Reno
Discover tips and strategies to find the most affordable flight options for your journey from Des Moines (DSM) to Reno (RNO). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated February 25, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $252 (Kiwi.com) |
One-way from | $179 (American Airlines) |
Popular in | December |
Cheapest in | September |
Average price | $447 |
Cheapflights Fare Finder
Customize your flight search to find flights from Des Moines to Reno that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 25, 2026.
Use the filters below to find and compare flights from Des Moines to Reno that are best for you.
Fly from
Fly to
Route
Depart
Return
Des MoinesReno
DSM - RNO
DSMRNO
Des Moines
Sat 4/18
2:44 pm-9:55 pm
1 stop9h 11m
Reno
Wed 4/22
10:34 am-9:12 pm
2 stops8h 38m
$342
Des MoinesReno
DSM - RNO
DSMRNO
Des Moines
Sat 5/2
3:20 pm-10:51 pm
1 stop9h 31m
Reno
Thu 5/7
9:16 am-4:15 pm
1 stop4h 59m
$351
Des MoinesReno
DSM - RNO
DSMRNO
Des Moines
Wed 4/8
6:30 pm-9:35 pm
1 stop5h 05m
Reno
Wed 4/15
10:55 am-9:15 pm
2 stops8h 20m
$357
Des MoinesReno
DSM - RNO
DSMRNO
Des Moines
Thu 5/7
1:55 pm-11:40 pm
1 stop11h 45m
Reno
Mon 5/11
2:50 pm-9:55 pm
1 stop5h 05m
$357
Des MoinesReno
DSM - RNO
DSMRNO
Des Moines
Mon 5/4
2:44 pm-9:55 pm
1 stop9h 11m
Reno
Fri 5/8
10:50 pm-11:08 am
1 stop10h 18m
$370
Des MoinesReno
DSM - RNO
DSMRNO
Des Moines
Sun 5/3
8:40 pm-12:05 am
1 stop5h 25m
Reno
Thu 5/7
5:10 am-6:35 pm
1 stop11h 25m
$395
Des MoinesReno
DSM - RNO
DSMRNO
Des Moines
Sun 3/8
7:00 am-1:46 pm
2 stops32h 46m
Reno
Thu 3/12
8:38 pm-10:34 pm
1 stop23h 56m
$411
Des MoinesReno
DSM - RNO
DSMRNO
Des Moines
Mon 3/30
4:25 pm-11:35 pm
2 stops9h 10m
Reno
Fri 4/3
11:10 pm-10:48 am
1 stop9h 38m
$423
Des MoinesReno
DSM - RNO
DSMRNO
Des Moines
Sun 5/3
2:38 pm-6:27 pm
1 stop5h 49m
Reno
Thu 5/7
9:51 am-5:29 pm
1 stop5h 38m
$427
Des MoinesReno
DSM - RNO
DSMRNO
Des Moines
Thu 4/2
2:15 pm-8:55 pm
2 stops8h 40m
$194
Showing 1-10 of 12 resultsSorted by cheapest first
Compare providers for flights from Des Moines to Reno
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Des Moines to Reno in February.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Des Moines-Reno flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Des Moines-Reno flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Des Moines-Reno flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Des Moines-Reno flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Des Moines-Reno flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Des Moines to Reno
Have a flexible travel schedule? Discover the best time to fly to Reno from Des Moines with our price prediction graph.
DSM-RNO
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Des Moines to Reno
Reviews of airlines servicing Reno
Get insights into the airlines that provide service to Reno. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Reno. Reviews last updated February 25, 2026.
Get a feel of what it's like to fly with Southwest, United Airlines, and American Airlines from Des Moines to Reno by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.6
Overall
8.0
Boarding
8.1
Food
7.0
Comfort
8.0
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Crew
8.6
Overall
8.0
Boarding
8.1
Food
7.0
Comfort
8.0
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Crew
8.6
Overall
8.0
Boarding
8.1
Food
7.0
Comfort
8.0
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Crew
8.6
Overall
8.0
Boarding
8.1
Food
7.0
Comfort
8.0
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Related info for your journey
Find useful and relevant information for your journey from Des Moines to Reno. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Reno?
Book flights to Reno if you plan to visit one of these locationsStateline
Sparks
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Susanville
Kirkwood
Truckee
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Des Moines and Reno flights
Browse other Des Moines and Reno flight options. Last updated on February 25, 2026.
Other flights from Des Moines
Browse through other flights departing from Des Moines. Flights are based on user searches made on Cheapflights and were last updated on February 25, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Other flights to Reno
Explore flights to Reno departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on February 25, 2026.
Top 3 airlines flying from Des Moines to Reno
Discover the top 3 airlines that operate flights from Des Moines to Reno. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 25, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$262 | Average$426 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$290 | Average$472 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$329 | Average$441 | FlexibilityNo cancel fee | On-time69% |