$144+ Cheap flights from Des Moines to Reno (DSM - RNO)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/27. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — RNO
May 23 — May 301
Round-trip
1 adult, Economy
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Find cheap flights from Des Moines to Reno with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Des Moines to Reno
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Cheapest flights from Des Moines to RenoExplore the most affordable flight options available from Des Moines to Reno. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 23, 2026.
Explore the most affordable flight options available from Des Moines to Reno. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 23, 2026.
This Kiwi.com deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/48:15 pm
DSM
- RNO
1 stop20h 20m
Multiple Airlines
Tue 5/263:29 pm
RNO
- DSM
1 stop19h 30m
Multiple Airlines
Deal found 4/21![Multiple Airlines logo]()
$235
This Kiwi.com deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/113:46 pm
DSM
- RNO
1 stop6h 18m
Multiple Airlines
Tue 5/263:29 pm
RNO
- DSM
1 stop19h 30m
Multiple Airlines
Deal found 4/21![Multiple Airlines logo]()
$269
This Kiwi.com deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/153:32 pm
DSM
- RNO
1 stop24h 56m
Multiple Airlines
Tue 5/263:29 pm
RNO
- DSM
1 stop19h 30m
Multiple Airlines
Deal found 4/21![Multiple Airlines logo]()
$272
This Kiwi.com deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/259:42 pm
DSM
- RNO
1 stop18h 53m
Multiple Airlines
Thu 5/288:59 pm
RNO
- DSM
2 stops23h 49m
Multiple Airlines
Deal found 4/21![Multiple Airlines logo]()
$277
This Kiwi.com deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/89:56 pm
DSM
- RNO
1 stop15h 19m
Multiple Airlines
Tue 6/1612:10 pm
RNO
- DSM
1 stop22h 45m
Multiple Airlines
Deal found 4/19![Multiple Airlines logo]()
$295
This Kiwi.com deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/113:46 pm
DSM
- RNO
1 stop26h 04m
Multiple Airlines
Thu 5/218:59 pm
RNO
- DSM
1 stop21h 53m
Multiple Airlines
Deal found 4/21![Multiple Airlines logo]()
$310
This Delta deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/292:15 pm
DSM
- RNO
1 stop9h 39m
Delta
Tue 9/110:50 pm
RNO
- DSM
1 stop9h 24m
Delta
Deal found 4/20![Delta logo]()
$317
This Kiwi.com deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/89:56 pm
DSM
- RNO
1 stop15h 19m
Multiple Airlines
Wed 6/173:08 pm
RNO
- DSM
1 stop26h 38m
Multiple Airlines
Deal found 4/19![Multiple Airlines logo]()
$322
Best flights from Des Moines to RenoDiscover carefully curated flight deals from Des Moines to Reno that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 23, 2026.
Discover carefully curated flight deals from Des Moines to Reno that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 23, 2026.
This Kiwi.com deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/49:01 pm
DSM
- RNO
1 stop19h 27m
Multiple Airlines
Thu 6/118:59 pm
RNO
- DSM
1 stop22h 07m
Multiple Airlines
Deal found 4/20![Multiple Airlines logo]()
$419
This Delta deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/152:45 pm
DSM
- RNO
1 stop7h 04m
Delta
Wed 6/176:28 am
RNO
- DSM
1 stop5h 37m
Delta
Deal found 4/22![Delta logo]()
$447
This Southwest deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/151:45 pm
DSM
- RNO
1 stop11h 55m
Southwest
Mon 5/1812:55 pm
RNO
- DSM
2 stops8h 10m
Southwest
Deal found 4/19![Southwest logo]()
$476
This Delta deal was found by Cheapflights users on 4/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/92:48 pm
DSM
- RNO
1 stop8h 56m
Delta
Fri 6/127:00 pm
RNO
- DSM
2 stops13h 14m
Delta
Deal found 4/18![Delta logo]()
$452
This Southwest deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/412:05 pm
DSM
- RNO
2 stops13h 30m
Southwest
Thu 6/115:40 am
RNO
- DSM
2 stops8h 20m
Southwest
Deal found 4/20![Southwest logo]()
$483
This Delta deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/162:45 pm
DSM
- RNO
2 stops11h 00m
Delta
Tue 7/2110:54 pm
RNO
- DSM
1 stop9h 51m
Delta
Deal found 4/19![Delta logo]()
$452
This Delta deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/96:03 pm
DSM
- RNO
2 stops7h 44m
Delta
Mon 6/1510:54 pm
RNO
- DSM
1 stop9h 49m
Delta
Deal found 4/19![Delta logo]()
$452
This Southwest deal was found by Cheapflights users on 4/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/61:30 pm
DSM
- RNO
1 stop6h 10m
Southwest
Mon 7/1312:40 pm
RNO
- DSM
2 stops7h 40m
Southwest
Deal found 4/18![Southwest logo]()
$498
Last-minute flights from Des Moines to RenoDiscover last-minute flight deals from Des Moines to Reno. Data last updated April 23, 2026 and is based on user searches.
Discover last-minute flight deals from Des Moines to Reno. Data last updated April 23, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/48:15 pm
DSM
- RNO
1 stop20h 20m
Multiple Airlines
Tue 5/263:29 pm
RNO
- DSM
1 stop19h 30m
Multiple Airlines
Deal found 4/21![Multiple Airlines logo]()
$235
This Kiwi.com deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/113:46 pm
DSM
- RNO
1 stop6h 18m
Multiple Airlines
Tue 5/263:29 pm
RNO
- DSM
1 stop19h 30m
Multiple Airlines
Deal found 4/21![Multiple Airlines logo]()
$269
This Kiwi.com deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/113:46 pm
DSM
- RNO
1 stop26h 04m
Multiple Airlines
Thu 5/218:59 pm
RNO
- DSM
1 stop21h 53m
Multiple Airlines
Deal found 4/21![Multiple Airlines logo]()
$310
This Kiwi.com deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/1110:00 am
DSM
- RNO
2 stops27h 15m
Multiple Airlines
Fri 5/2212:10 pm
RNO
- DSM
1 stop6h 42m
Multiple Airlines
Deal found 4/21![Multiple Airlines logo]()
$345
This Kiwi.com deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/153:32 pm
DSM
- RNO
1 stop24h 56m
Multiple Airlines
Tue 5/263:29 pm
RNO
- DSM
1 stop19h 30m
Multiple Airlines
Deal found 4/21![Multiple Airlines logo]()
$272
This Kiwi.com deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/153:32 pm
DSM
- RNO
1 stop24h 56m
Multiple Airlines
Mon 5/1811:27 am
RNO
- DSM
1 stop9h 06m
Multiple Airlines
Deal found 4/19![Multiple Airlines logo]()
$340
This Kiwi.com deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/259:42 pm
DSM
- RNO
1 stop18h 53m
Multiple Airlines
Thu 5/288:59 pm
RNO
- DSM
2 stops23h 49m
Multiple Airlines
Deal found 4/21![Multiple Airlines logo]()
$277
One-way flights from Des Moines to RenoSearch for one-way flight options from Des Moines to Reno. Find affordable one-way fares based on user searches. Data last updated April 23, 2026.
Search for one-way flight options from Des Moines to Reno. Find affordable one-way fares based on user searches. Data last updated April 23, 2026.
This American Airlines deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/272:23 pm
DSM
- RNO
1 stop6h 04m
American Airlines
Deal found 4/21![American Airlines logo]()
$144
This Kiwi.com deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/112:16 pm
DSM
- RNO
2 stops27h 34m
Frontier
Deal found 4/22![Frontier logo]()
$182
This Kiwi.com deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/113:46 pm
DSM
- RNO
1 stop6h 18m
Multiple Airlines
Deal found 4/22![Multiple Airlines logo]()
$188
This Kiwi.com deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/272:16 pm
DSM
- RNO
3 stops46h 59m
Multiple Airlines
Deal found 4/21![Multiple Airlines logo]()
$202
This Delta deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/72:45 pm
DSM
- RNO
2 stops10h 47m
Delta
Deal found 4/23![Delta logo]()
$229
This Southwest deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/76:10 pm
DSM
- RNO
1 stop6h 50m
Southwest
Deal found 4/23![Southwest logo]()
$270
This Delta deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/62:44 pm
DSM
- RNO
1 stop9h 11m
Delta
Deal found 4/20![Delta logo]()
$284
This United Airlines deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/68:00 am
DSM
- RNO
3 stops17h 59m
United Airlines
Deal found 4/20![United Airlines logo]()
$772
Find flight deals from Des Moines to Reno
Discover tips and strategies to find the most affordable flight options for your journey from Des Moines (DSM) to Reno (RNO). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated April 23, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $235 (Kiwi.com) |
One-way from | $144 (American Airlines) |
Popular in | December |
Cheapest in | September |
Average price | $382 |
Cheapflights Fare Finder
Customize your flight search to find flights from Des Moines to Reno that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 23, 2026.
Use the filters below to find and compare flights from Des Moines to Reno that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Des MoinesReno
DSM - RNO
DSMRNO
Des Moines
Thu 6/4
9:01 pm-2:28 pm
1 stop19h 27m
Reno
Thu 6/11
8:59 pm-9:06 pm
1 stop22h 07m
$419
Quickest round-trip
Des MoinesReno
DSM - RNO
DSMRNO
Des Moines
Mon 6/15
2:45 pm-7:49 pm
1 stop7h 04m
Reno
Wed 6/17
6:28 am-2:05 pm
1 stop5h 37m
$447
Des MoinesReno
DSM - RNO
DSMRNO
Des Moines
Tue 6/9
2:48 pm-9:44 pm
1 stop8h 56m
Reno
Fri 6/12
7:00 pm-10:14 am
2 stops13h 14m
$452
Des MoinesReno
DSM - RNO
DSMRNO
Des Moines
Thu 7/16
2:45 pm-11:45 pm
2 stops11h 00m
Reno
Tue 7/21
10:54 pm-10:45 am
1 stop9h 51m
$452
Des MoinesReno
DSM - RNO
DSMRNO
Des Moines
Tue 6/9
6:03 pm-11:47 pm
2 stops7h 44m
Reno
Mon 6/15
10:54 pm-10:43 am
1 stop9h 49m
$452
Des MoinesReno
DSM - RNO
DSMRNO
Des Moines
Fri 5/15
1:45 pm-11:40 pm
1 stop11h 55m
Reno
Mon 5/18
12:55 pm-11:05 pm
2 stops8h 10m
$476
Des MoinesReno
DSM - RNO
DSMRNO
Des Moines
Thu 6/4
12:05 pm-11:35 pm
2 stops13h 30m
Reno
Thu 6/11
5:40 am-4:00 pm
2 stops8h 20m
$483
Des MoinesReno
DSM - RNO
DSMRNO
Des Moines
Mon 7/6
1:30 pm-5:40 pm
1 stop6h 10m
Reno
Mon 7/13
12:40 pm-10:20 pm
2 stops7h 40m
$498
Cheapest one-way
Quickest one-way
Des MoinesReno
DSM - RNO
DSMRNO
Des Moines
Wed 5/27
2:23 pm-6:27 pm
1 stop6h 04m
$144
Des MoinesReno
DSM - RNO
DSMRNO
Des Moines
Mon 5/11
2:16 pm-3:50 pm
2 stops27h 34m
$182
Showing 1-10 of 16 resultsSorted by cheapest first
Compare providers for flights from Des Moines to Reno
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Des Moines to Reno in April.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Des Moines-Reno flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Des Moines-Reno flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Des Moines-Reno flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Des Moines-Reno flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Des Moines-Reno flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Des Moines to Reno
Have a flexible travel schedule? Discover the best time to fly to Reno from Des Moines with our price prediction graph.
DSM-RNO
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Des Moines to Reno
How far ahead should I book a flight from Des Moines to Reno?
Use this chart to determine the optimal time to book a round-trip flight from Des Moines to Reno. Price data was last updated on April 17, 2026.
The price you pay for your flight from Des Moines to Reno may vary depending on when you book. For the best chance of a lower fare, look to book 22 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.
What is the cheapest month to book a flight from Des Moines to Reno?
Currently, September is the cheapest month in which you can book a flight from Des Moines to Reno (average of $341). Flying from Des Moines to Reno in December is currently the most expensive (average of $522). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Des Moines to Reno?
Reviews of airlines servicing Reno
Get insights into the airlines that provide service to Reno. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Reno. Reviews last updated April 23, 2026.
Get a feel of what it's like to fly with Southwest,United Airlines, andAmerican Airlines from Des Moines to Reno by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Comfort
8.0
Crew
8.6
Entertainment
7.5
Overall
8.0
Boarding
8.1
Food
7.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Comfort
8.0
Crew
8.6
Entertainment
7.5
Overall
8.0
Boarding
8.1
Food
7.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Comfort
8.0
Crew
8.6
Entertainment
7.5
Overall
8.0
Boarding
8.1
Food
7.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Comfort
8.0
Crew
8.6
Entertainment
7.5
Overall
8.0
Boarding
8.1
Food
7.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Related info for your journey
Find useful and relevant information for your journey from Des Moines to Reno. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Reno?
Book flights to Reno if you plan to visit one of these locationsStateline
Sparks
Olympic Valley
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Kirkwood
Truckee
Incline Village
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Des Moines and Reno flights
Browse other Des Moines and Reno flight options. Last updated on April 23, 2026.
Other flights from Des Moines
Browse through other flights departing from Des Moines. Flights are based on user searches made on Cheapflights and were last updated on April 23, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Other flights to Reno
Explore flights to Reno departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on April 23, 2026.
Top 3 airlines flying from Des Moines to Reno
Discover the top 3 airlines that operate flights from Des Moines to Reno. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 23, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$262 | Average$402 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$290 | Average$472 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$329 | Average$441 | FlexibilityNo cancel fee | On-time69% |