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$324+ Cheap flights from Florence, SC to Portland (FLO - PDX)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/8. Fares are subject to change and may not be available on all flights or dates of travel.
FLO — PDX
Oct 11 — Oct 181
Sat 10/11
Sat 10/18
1 adult, Economy
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Cheap flight deals from Florence to Portland

Discover tips and strategies to find the most affordable flight options for your journey from Florence (FLO) to Portland (PDX). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 11, 2025.

Round-trip from

$780
(American Airlines)

One-way from

$324
(American Airlines)
From Florence to Portland
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One-way flight from Florence to Portland
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Find flight deals from Florence to Portland

Best flights from Florence to Portland
Discover carefully curated flight deals from Florence to Portland that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 11, 2025.

This American Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/105:13 amFLO - PDX
2 stops18h 11mAmerican Airlines
Wed 3/116:00 amPDX - FLO
2 stops14h 38mAmerican Airlines
Deal found 9/9$780

Cheapflights Fare Finder

 
Customize your flight search to find flights from Florence to Portland that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
Use the filters below to find and compare flights from Florence to Portland that are best for you.

Fly from

Florence

Fly to

Portland

Route

Depart

Return

Price

FlorencePortland

FLO - PDX

FLOPDX

Florence

Tue 3/10

5:13 am-8:24 pm

2 stops18h 11m

Portland

Wed 3/11

6:00 am-11:38 pm

2 stops14h 38m

$780

FlorencePortland

FLO - PDX

FLOPDX

Florence

Wed 10/8

3:19 pm-11:06 pm

2 stops10h 47m

$324

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/10

Best time to book a flight from Florence to Portland

Have a flexible travel schedule? Discover the best time to fly to Portland from Florence with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Florence to Portland

What is the cheapest month to book a flight from Florence, South Carolina to Portland?

Currently, November is the cheapest month in which you can book a flight from Florence, South Carolina to Portland (average of $277). Flying from Florence, South Carolina to Portland in March is currently the most expensive (average of $368). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from Florence to Portland. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Florence, South Carolina to Portland?

    A quick flight from Florence, South Carolina to Portland can take about 18h 11m. American Airlines provides one of the quickest options available for as low as $780. Florence, South Carolina and Portland are separated by a distance of 2371 mi.

  • Can I find deals for flights from Florence to Portland that include hotel bookings?

    Yes. In addition to deals on Florence to Portland flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Florence to Portland?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Florence to Portland.

  • Can I find deals for business class flights from Florence to Portland?

    Yes. Cheapflights offers flight deals from Florence to Portland by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Florence, South Carolina to Portland?

    Currently, November is the cheapest month in which you can book a flight from Florence, South Carolina to Portland (average of $277). Flying from Florence, South Carolina to Portland in March is currently the most expensive (average of $368). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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