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$133+ Cheap flights from Missouri to Portland, ME (PWM)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/23. Fares are subject to change and may not be available on all flights or dates of travel.
STL — PWM
Nov 29 — Dec 61
Sat 11/29
Sat 12/6
1 adult, Economy
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Find flight deals from Missouri to Portland

Cheapest flights from Missouri to Portland
Explore the most affordable flight options available from Missouri to Portland. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 30, 2025.

This Delta deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/1010:41 amMCI - PWM
1 stop4h 26mDelta
Tue 12/164:43 pmPWM - MCI
1 stop7h 16mDelta
Deal found 10/29$313
This Kiwi.com deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/116:00 amMCI - PWM
1 stop27h 36mMultiple Airlines
Fri 11/149:46 amPWM - MCI
1 stop27h 42mMultiple Airlines
Deal found 10/28$317
This American Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/101:40 pmMCI - PWM
1 stop8h 12mAmerican Airlines
Tue 12/165:34 amPWM - MCI
2 stops9h 16mAmerican Airlines
Deal found 10/28$318
This American Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/232:04 pmSTL - PWM
1 stop7h 47mAmerican Airlines
Thu 1/15:20 pmPWM - STL
1 stop5h 25mAmerican Airlines
Deal found 10/28$335
This Southwest deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/59:40 amSTL - PWM
1 stop4h 15mSouthwest
Tue 12/93:30 pmPWM - STL
1 stop7h 30mSouthwest
Deal found 10/28$353
This Kiwi.com deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/136:00 amMCI - PWM
1 stop26h 06mMultiple Airlines
Mon 11/176:05 pmPWM - MCI
2 stops43h 23mMultiple Airlines
Deal found 10/29$355
This Delta deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/261:55 pmSTL - PWM
1 stop7h 24mDelta
Wed 12/34:53 pmPWM - STL
1 stop4h 54mDelta
Deal found 10/29$363
This Kiwi.com deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/1011:12 amMCI - PWM
2 stops46h 24mMultiple Airlines
Mon 11/179:46 amPWM - MCI
1 stop27h 42mMultiple Airlines
Deal found 10/27$375
This American Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/209:50 amSTL - PWM
1 stop5h 50mAmerican Airlines
Sat 11/226:00 amPWM - STL
1 stop5h 14mAmerican Airlines
Deal found 10/28$382
This Southwest deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/201:15 pmSTL - PWM
2 stops8h 00mSouthwest
Sat 11/225:40 pmPWM - STL
1 stop6h 40mSouthwest
Deal found 10/28$397
This United Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/168:00 amSGF - PWM
1 stop5h 12mUnited Airlines
Sun 11/235:00 pmPWM - SGF
1 stop6h 13mUnited Airlines
Deal found 10/29$414
This Delta deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/206:00 amSTL - PWM
1 stop5h 30mDelta
Sun 11/2312:48 pmPWM - STL
1 stop5h 21mDelta
Deal found 10/28$427

Cheap flight deals from Missouri to Portland

Keep the following information in mind while searching for Missouri to Portland flight deals. Data was last updated October 30, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$304
(American Airlines)

One-way from

$133
(Kiwi.com)

Popular in

August

Cheapest in

January

Average price

$416
Provider with most accurate pricing for Lambert-St Louis-Portland flight deals.
Search Deals
Provider most trusted by Cheapflights users for Lambert-St Louis-Portland flights.
Search Deals
From Missouri to Portland
Search Deals
One-way flight from Missouri to Portland
Search Deals
Highest demand for flights based on searches. 1% potential increase in price ($7 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($6 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in October 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Missouri to Portland that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 30, 2025.
Use the filters below to find and compare flights from Missouri to Portland that are best for you.

Fly from

Missouri

Fly to

Portland

Route

Depart

Return

Price

Kansas CityPortland

MCI - PWM

MCIPWM

Kansas City

Thu 11/13

6:00 am-9:06 am

1 stop26h 06m

Portland

Mon 11/17

9:46 am-12:28 pm

1 stop27h 42m

$313

Kansas CityPortland

MCI - PWM

MCIPWM

Kansas City

Wed 12/10

3:27 pm-10:23 pm

1 stop5h 56m

Portland

Tue 12/16

6:08 am-2:21 pm

1 stop9h 13m

$313

SpringfieldPortland

SGF - PWM

SGFPWM

Springfield-Branson

Thu 1/29

12:45 pm-10:07 pm

1 stop8h 22m

Portland

Sun 2/1

7:00 am-12:15 pm

1 stop6h 15m

$314

Kansas CityPortland

MCI - PWM

MCIPWM

Kansas City

Wed 12/10

1:40 pm-10:52 pm

1 stop8h 12m

Portland

Tue 12/16

5:34 am-1:50 pm

2 stops9h 16m

$318

St. LouisPortland

STL - PWM

STLPWM

Lambert-St Louis

Fri 12/5

9:40 am-2:55 pm

1 stop4h 15m

Portland

Tue 12/9

3:30 pm-10:00 pm

1 stop7h 30m

$353

St. LouisPortland

STL - PWM

STLPWM

Lambert-St Louis

Tue 12/23

2:04 pm-10:51 pm

1 stop7h 47m

Portland

Thu 1/1

5:20 pm-9:45 pm

1 stop5h 25m

$359

Kansas CityPortland

MCI - PWM

MCIPWM

Kansas City

Tue 11/11

6:00 am-10:41 am

2 stops27h 41m

Portland

Fri 11/14

9:46 am-12:28 pm

1 stop27h 42m

$361

St. LouisPortland

STL - PWM

STLPWM

Lambert-St Louis

Wed 11/26

1:55 pm-10:19 pm

1 stop7h 24m

Portland

Wed 12/3

4:53 pm-8:47 pm

1 stop4h 54m

$363

SpringfieldPortland

SGF - PWM

SGFPWM

Springfield-Branson

Sat 3/28

4:00 pm-9:59 pm

1 stop4h 59m

Portland

Tue 3/31

5:30 am-11:14 am

1 stop6h 44m

$374

Kansas CityPortland

MCI - PWM

MCIPWM

Kansas City

Mon 11/10

11:12 am-10:36 am

2 stops46h 24m

Portland

Mon 11/17

9:46 am-12:28 pm

1 stop27h 42m

$375

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/28

Showing 1-10 of 45 results
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Best time to book a flight from Missouri to Portland

Have a flexible travel schedule? Discover the best time to fly to Portland from Missouri with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Missouri to Portland

What is the cheapest month to book a flight from Missouri to Portland, Maine?

Currently, November is the cheapest month in which you can book a flight from Missouri to Portland, Maine (average of $114). Flying from Missouri to Portland, Maine in June is currently the most expensive (average of $266). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MO to PWM?

Find hourly flight availability from Missouri to Portland. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 30, 2025.

It’s optimal to fly from Missouri to Portland, Maine in the evening. By choosing this option you can save up to 48% on the cost of your flight, compared to a flight in the morning.

Related info for your journey

Find useful and relevant information for your journey from Missouri to Portland. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Portland from Missouri?

    If you book a flight to Portland from Missouri, you will be flying to Portland, which is the city’s only airport. Portland (PWM) is located 2.9 mi from the center of Portland.

  • How long is the flight from Missouri to Portland, Maine?

    Airlines like Delta, American Airlines, and Southwest fly from Missouri to Portland, Maine in about 4h 15m. The time it takes to get you to your destination can typically vary by up to 4h 07m. The distance from Missouri to Portland, Maine is about 1092 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from Missouri to Portland, Maine one-way?

    To fly one-way, consider booking your trip with Delta, which is currently one of the cheapest options available, starting at $169. United Airlines flights start at $189 while deals on American Airlines start at $300 one-way.

  • What are the most popular routes from Missouri to Portland, Maine?

    While some choose either Kansas City - Portland or Springfield-Branson - Portland, Lambert-St Louis - Portland is the most popular route from Missouri to Portland, Maine.

  • Can I find deals for flights from Missouri to Portland that include hotel bookings?

    Yes. In addition to deals on Missouri to Portland flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Missouri to Portland?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to Portland.

  • Can I find deals for business class flights from Missouri to Portland?

    Yes. Cheapflights offers flight deals from Missouri to Portland by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Missouri to Portland, Maine?

    Currently, November is the cheapest month in which you can book a flight from Missouri to Portland, Maine (average of $114). Flying from Missouri to Portland, Maine in June is currently the most expensive (average of $266). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Portland?

Book flights to Portland if you plan to visit one of these locations
North Conway
Brunswick
Auburn
Conway

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Top 4 airlines flying from Missouri to Portland

Discover the top 4 airlines that operate flights from Missouri to Portland. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 30, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$128Average$374FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$212Average$505FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$268Average$450FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$308Average$484FlexibilityNo cancel feeOn-time63%

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