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$168+ Cheap flights from Missouri to Portland, ME (PWM)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/30. Fares are subject to change and may not be available on all flights or dates of travel.
MCI — PWM
Jan 15 — Jan 221
Thu 1/15
Thu 1/22
1 adult, Economy
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Cheap flight deals from Missouri to Portland

Cheapest flights from Missouri to Portland
Explore the most affordable flight options available from Missouri to Portland. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 16, 2025.

This United Airlines deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/257:40 amMCI - PWM
1 stop5h 34mUnited Airlines
Mon 12/294:10 pmPWM - MCI
1 stop6h 40mUnited Airlines
Deal found 12/14$456
This United Airlines deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/308:15 amSTL - PWM
1 stop5h 25mUnited Airlines
Sat 1/35:30 amPWM - STL
1 stop5h 38mUnited Airlines
Deal found 12/15$502
This Kiwi.com deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/304:27 pmSTL - PWM
1 stop17h 09mMultiple Airlines
Sat 1/311:16 amPWM - STL
2 stops23h 24mMultiple Airlines
Deal found 12/15$611
This American Airlines deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/292:04 pmSTL - PWM
1 stop7h 47mAmerican Airlines
Fri 1/25:20 pmPWM - STL
1 stop5h 25mAmerican Airlines
Deal found 12/14$649
This United Airlines deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/245:46 pmMCI - PWM
1 stop5h 13mUnited Airlines
Sun 12/284:10 pmPWM - MCI
1 stop6h 40mUnited Airlines
Deal found 12/14$706
This American Airlines deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/246:10 amMCI - PWM
2 stops9h 29mAmerican Airlines
Sun 12/285:20 pmPWM - MCI
1 stop6h 39mAmerican Airlines
Deal found 12/14$724
This United Airlines deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/197:40 amMCI - PWM
1 stop5h 34mUnited Airlines
Tue 1/62:31 pmPWM - MCI
1 stop6h 25mUnited Airlines
Deal found 12/14$734
This Southwest deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/195:20 amMCI - PWM
1 stop4h 50mSouthwest
Tue 1/65:45 amPWM - MCI
2 stops9h 35mSouthwest
Deal found 12/14$739
This Kiwi.com deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/298:52 pmSTL - PWM
2 stops36h 44mMultiple Airlines
Fri 1/29:46 amPWM - STL
1 stop13h 47mMultiple Airlines
Deal found 12/14$777
This Kiwi.com deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/184:27 pmSTL - PWM
1 stop15h 39mMultiple Airlines
Sat 12/2011:16 amPWM - STL
2 stops24h 40mMultiple Airlines
Deal found 12/14$788
This American Airlines deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/176:00 amMCI - PWM
1 stop8h 27mAmerican Airlines
Sat 12/205:39 amPWM - MCI
1 stop17h 09mAmerican Airlines
Deal found 12/16$835
This United Airlines deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/293:10 pmSTL - PWM
1 stop5h 19mUnited Airlines
Fri 1/25:30 amPWM - STL
1 stop5h 38mUnited Airlines
Deal found 12/14$847

Find flight deals from Missouri to Portland

Keep the following information in mind while searching for Missouri to Portland flight deals. Data was last updated December 16, 2025.

Most accurate provider

Gotogate
3 stars

Most trusted provider

Gotogate
3 stars

Round-trip from

$303
(American Airlines)

One-way from

$168
(Kiwi.com)

Popular in

November

Cheapest in

September

Average price

$427
Provider with most accurate pricing for Lambert-St Louis-Boston Logan Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Lambert-St Louis-Boston Logan Intl flights.
Search Deals
From Missouri to Portland
Search Deals
One-way flight from Missouri to Portland
Search Deals
Highest demand for flights based on searches. 4% potential increase in price ($21 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 0% potential price decrease ($4 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Missouri to Portland that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 16, 2025.
Use the filters below to find and compare flights from Missouri to Portland that are best for you.

Fly from

Missouri

Fly to

Portland

Route

Depart

Return

Price

Kansas CityPortland

MCI - PWM

MCIPWM

Kansas City

Fri 1/16

5:04 pm-10:22 am

1 stop16h 18m

Portland

Mon 1/19

9:47 am-4:09 pm

1 stop31h 22m

$302

SpringfieldPortland

SGF - PWM

SGFPWM

Springfield-Branson

Fri 1/16

12:45 pm-10:07 pm

1 stop8h 22m

Portland

Tue 1/20

5:20 am-6:04 pm

2 stops13h 44m

$303

SpringfieldPortland

SGF - PWM

SGFPWM

Springfield-Branson

Mon 1/5

4:27 pm-10:51 pm

1 stop5h 24m

Portland

Sat 1/10

7:00 am-12:15 pm

1 stop6h 15m

$314

St. LouisPortland

STL - PWM

STLPWM

Lambert-St Louis

Thu 2/5

6:00 am-12:05 pm

1 stop5h 05m

Portland

Thu 2/5

5:07 pm-9:51 pm

1 stop5h 44m

$333

ColumbiaPortland

COU - PWM

COUPWM

Columbia Regional

Sat 2/14

3:10 pm-9:09 pm

1 stop4h 59m

Portland

Wed 2/18

6:00 am-2:28 pm

2 stops9h 28m

$354

Kansas CityPortland

MCI - PWM

MCIPWM

Kansas City

Wed 1/14

2:00 pm-10:15 pm

1 stop7h 15m

Portland

Wed 1/21

5:45 am-10:35 am

1 stop5h 50m

$357

St. LouisPortland

STL - PWM

STLPWM

Lambert-St Louis

Mon 1/12

8:05 am-2:39 pm

1 stop5h 34m

Portland

Fri 1/16

4:10 pm-10:58 pm

1 stop7h 48m

$371

SpringfieldPortland

SGF - PWM

SGFPWM

Springfield-Branson

Thu 1/29

12:45 pm-10:07 pm

1 stop8h 22m

Portland

Sun 2/1

7:00 am-12:15 pm

1 stop6h 15m

$379

SpringfieldPortland

SGF - PWM

SGFPWM

Springfield-Branson

Sat 1/17

7:45 am-2:39 pm

1 stop5h 54m

Portland

Wed 1/21

4:10 pm-9:58 pm

1 stop6h 48m

$384

Kansas CityPortland

MCI - PWM

MCIPWM

Kansas City

Thu 1/29

1:22 pm-10:27 pm

1 stop8h 05m

Portland

Sun 2/1

5:59 pm-11:04 pm

1 stop6h 05m

$389

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/14

Showing 1-10 of 29 results
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Best time to book a flight from Missouri to Portland

Have a flexible travel schedule? Discover the best time to fly to Portland from Missouri with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Missouri to Portland

What is the cheapest month to book a flight from Missouri to Portland, Maine?

Currently, January is the cheapest month in which you can book a flight from Missouri to Portland, Maine (average of $121). Flying from Missouri to Portland, Maine in June is currently the most expensive (average of $266). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MO to PWM?

Find hourly flight availability from Missouri to Portland. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 16, 2025.

It’s optimal to fly from Missouri to Portland, Maine in the evening. By choosing this option you can save up to 48% on the cost of your flight, compared to a flight in the morning.

Related info for your journey

Find useful and relevant information for your journey from Missouri to Portland. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Portland from Missouri?

    If you book a flight to Portland from Missouri, you will be flying to Portland, which is the city’s only airport. Portland (PWM) is located 2.9 mi from the center of Portland.

  • How long is the flight from Missouri to Portland, Maine?

    Airlines like American Airlines, United Airlines, and Southwest fly from Missouri to Portland, Maine in about 4h 59m. The time it takes to get you to your destination can typically vary by up to 3h 23m. The distance from Missouri to Portland, Maine is about 1182 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from Missouri to Portland, Maine one-way?

    To fly one-way, consider booking your trip with Delta, which is currently one of the cheapest options available, starting at $128. American Airlines flights start at $142 while deals on Southwest start at $143 one-way.

  • What are the most popular routes from Missouri to Portland, Maine?

    While some choose either Springfield-Branson - Portland or Lambert-St Louis - Portland, Kansas City - Portland is the most popular route from Missouri to Portland, Maine.

  • Can I find deals for flights from Missouri to Portland that include hotel bookings?

    Yes. In addition to deals on Missouri to Portland flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Missouri to Portland?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to Portland.

  • Can I find deals for business class flights from Missouri to Portland?

    Yes. Cheapflights offers flight deals from Missouri to Portland by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Missouri to Portland, Maine?

    Currently, January is the cheapest month in which you can book a flight from Missouri to Portland, Maine (average of $121). Flying from Missouri to Portland, Maine in June is currently the most expensive (average of $266). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Portland?

Book flights to Portland if you plan to visit one of these locations
North Conway
Brunswick
Auburn
Conway

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Top 4 airlines flying from Missouri to Portland

Discover the top 4 airlines that operate flights from Missouri to Portland. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 16, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$128Average$383FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$212Average$505FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$268Average$447FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$284Average$494FlexibilityNo cancel feeOn-time63%

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