$91+ Cheap flights from Missouri to Pittsburgh (PIT)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/14. Fares are subject to change and may not be available on all flights or dates of travel.
STL — PIT
May 19 — May 261
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from Missouri to Pittsburgh with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Missouri to Pittsburgh
Cheapest
Best
Last-minute
One-way
Cheapest flights from Missouri to PittsburghExplore the most affordable flight options available from Missouri to Pittsburgh. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 19, 2026.
Explore the most affordable flight options available from Missouri to Pittsburgh. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 19, 2026.
This Frontier deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/284:19 pm
STL
- PIT
1 stop26h 01m
Frontier
Mon 6/18:15 pm
PIT
- STL
1 stop28h 42m
Frontier
Deal found 4/14![Frontier logo]()
$181
This Southwest deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/1310:15 am
STL
- PIT
Nonstop1h 40m
Southwest
Wed 5/207:10 pm
PIT
- STL
Nonstop1h 50m
Southwest
Deal found 4/15![Southwest logo]()
$217
This American Airlines deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/135:51 am
STL
- PIT
1 stop9h 57m
American Airlines
Wed 5/209:19 am
PIT
- STL
1 stop7h 41m
American Airlines
Deal found 4/15![American Airlines logo]()
$223
This Trip.com deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/84:19 pm
STL
- PIT
1 stop26h 01m
Frontier
Sun 5/108:05 pm
PIT
- STL
1 stop29h 16m
Frontier
Deal found 4/13![Frontier logo]()
$231
This Delta deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/96:00 am
STL
- PIT
1 stop5h 44m
Delta
Mon 5/117:50 pm
PIT
- STL
1 stop5h 09m
Delta
Deal found 4/16![Delta logo]()
$235
This Southwest deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/238:30 am
STL
- PIT
1 stop8h 15m
Southwest
Tue 6/306:45 am
PIT
- STL
Nonstop1h 45m
Southwest
Deal found 4/16![Southwest logo]()
$236
This Southwest deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/167:10 pm
STL
- PIT
Nonstop1h 35m
Southwest
Tue 6/237:45 pm
PIT
- STL
Nonstop1h 45m
Southwest
Deal found 4/14![Southwest logo]()
$237
This Kiwi.com deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/810:35 am
MCI
- PIT
1 stop7h 45m
Multiple Airlines
Sat 5/98:15 pm
PIT
- MCI
1 stop14h 14m
Multiple Airlines
Deal found 4/14![Multiple Airlines logo]()
$238
This Southwest deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/210:25 am
STL
- PIT
1 stop3h 45m
Southwest
Tue 6/912:45 pm
PIT
- STL
2 stops6h 40m
Southwest
Deal found 4/15![Southwest logo]()
$240
This Southwest deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/2810:15 am
STL
- PIT
Nonstop1h 40m
Southwest
Mon 6/18:40 am
PIT
- STL
1 stop5h 15m
Southwest
Deal found 4/14![Southwest logo]()
$250
This Kiwi.com deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/1510:35 am
MCI
- PIT
1 stop28h 28m
Multiple Airlines
Sun 5/178:15 pm
PIT
- MCI
1 stop14h 14m
Multiple Airlines
Deal found 4/14![Multiple Airlines logo]()
$258
This Kiwi.com deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/1410:35 am
MCI
- PIT
1 stop21h 14m
Multiple Airlines
Fri 5/154:58 pm
PIT
- MCI
1 stop17h 31m
Multiple Airlines
Deal found 4/14![Multiple Airlines logo]()
$286
Best flights from Missouri to PittsburghDiscover carefully curated flight deals from Missouri to Pittsburgh that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 19, 2026.
Discover carefully curated flight deals from Missouri to Pittsburgh that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 19, 2026.
This Southwest deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/137:35 am
STL
- PIT
1 stop4h 15m
Southwest
Wed 5/207:10 pm
PIT
- STL
Nonstop1h 50m
Southwest
Deal found 4/15![Southwest logo]()
$226
This Delta deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/96:00 am
STL
- PIT
1 stop5h 44m
Delta
Mon 5/117:50 pm
PIT
- STL
1 stop5h 09m
Delta
Deal found 4/16![Delta logo]()
$235
This United Airlines deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/215:00 am
STL
- PIT
1 stop3h 54m
United Airlines
Tue 8/257:28 pm
PIT
- STL
1 stop5h 09m
United Airlines
Deal found 4/15![United Airlines logo]()
$308
This American Airlines deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/2810:54 am
SGF
- PIT
1 stop5h 12m
American Airlines
Mon 5/47:12 pm
PIT
- SGF
1 stop4h 33m
American Airlines
Deal found 4/16![American Airlines logo]()
$379
This Southwest deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/1110:15 am
STL
- PIT
Nonstop1h 40m
Southwest
Mon 5/186:55 am
PIT
- STL
Nonstop1h 50m
Southwest
Deal found 4/16![Southwest logo]()
$265
This United Airlines deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/1311:23 am
COU
- PIT
1 stop4h 42m
United Airlines
Sun 7/196:16 pm
PIT
- COU
1 stop7h 17m
United Airlines
Deal found 4/16![United Airlines logo]()
$318
This Southwest deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/163:15 pm
STL
- PIT
2 stops6h 10m
Southwest
Tue 6/235:10 am
PIT
- STL
2 stops8h 25m
Southwest
Deal found 4/14![Southwest logo]()
$297
This Delta deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/612:07 pm
SGF
- PIT
1 stop4h 37m
Delta
Tue 6/91:57 pm
PIT
- SGF
1 stop5h 15m
Delta
Deal found 4/15![Delta logo]()
$329
This United Airlines deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/218:00 am
COU
- PIT
1 stop4h 04m
United Airlines
Tue 8/256:10 am
PIT
- COU
2 stops9h 20m
United Airlines
Deal found 4/15![United Airlines logo]()
$324
This Southwest deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/94:10 pm
MCI
- PIT
1 stop7h 30m
Southwest
Tue 6/233:55 pm
PIT
- MCI
1 stop7h 05m
Southwest
Deal found 4/16![Southwest logo]()
$307
This Delta deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/105:19 pm
STL
- PIT
1 stop4h 49m
Delta
Sun 7/125:25 am
PIT
- STL
1 stop5h 18m
Delta
Deal found 4/13![Delta logo]()
$351
This United Airlines deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/276:00 am
STL
- PIT
1 stop6h 09m
United Airlines
Thu 5/286:10 am
PIT
- STL
1 stop5h 17m
United Airlines
Deal found 4/13![United Airlines logo]()
$331
This Southwest deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/122:10 pm
MCI
- PIT
2 stops5h 35m
Southwest
Tue 5/197:10 pm
PIT
- MCI
1 stop3h 50m
Southwest
Deal found 4/14![Southwest logo]()
$312
This Delta deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/176:00 am
SGF
- PIT
1 stop5h 52m
Delta
Fri 6/266:20 pm
PIT
- SGF
1 stop4h 49m
Delta
Deal found 4/15![Delta logo]()
$354
This United Airlines deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/13:10 pm
COU
- PIT
1 stop4h 12m
United Airlines
Tue 5/56:10 am
PIT
- COU
2 stops9h 22m
United Airlines
Deal found 4/16![United Airlines logo]()
$334
This Southwest deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/2110:10 am
STL
- PIT
1 stop5h 55m
Southwest
Tue 8/256:40 am
PIT
- STL
Nonstop1h 40m
Southwest
Deal found 4/15![Southwest logo]()
$315
This American Airlines deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/218:09 am
COU
- PIT
2 stops7h 08m
American Airlines
Tue 8/2512:24 pm
PIT
- COU
2 stops9h 52m
American Airlines
Deal found 4/15![American Airlines logo]()
$527
This Delta deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/166:42 pm
MCI
- PIT
1 stop5h 08m
Delta
Sun 7/197:02 am
PIT
- MCI
1 stop6h 09m
Delta
Deal found 4/13![Delta logo]()
$407
This Southwest deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/87:40 pm
STL
- PIT
Nonstop1h 35m
Southwest
Sun 5/108:15 pm
PIT
- STL
Nonstop1h 50m
Southwest
Deal found 4/13![Southwest logo]()
$345
This United Airlines deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/21:35 pm
SGF
- PIT
2 stops9h 24m
United Airlines
Wed 5/67:05 am
PIT
- SGF
1 stop4h 35m
United Airlines
Deal found 4/17![United Airlines logo]()
$384
This United Airlines deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/256:36 pm
MCI
- PIT
1 stop4h 39m
United Airlines
Wed 8/2610:54 am
PIT
- MCI
1 stop5h 58m
United Airlines
Deal found 4/16![United Airlines logo]()
$387
This Southwest deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/118:05 am
MCI
- PIT
2 stops5h 45m
Southwest
Tue 6/164:45 pm
PIT
- MCI
1 stop4h 50m
Southwest
Deal found 4/15![Southwest logo]()
$372
This Delta deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/156:58 pm
SGF
- PIT
2 stops15h 20m
Delta
Sun 7/2611:48 am
PIT
- SGF
1 stop7h 25m
Delta
Deal found 4/15![Delta logo]()
$467
This United Airlines deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/206:56 pm
MCI
- PIT
1 stop4h 03m
United Airlines
Wed 5/276:10 am
PIT
- MCI
2 stops9h 10m
United Airlines
Deal found 4/15![United Airlines logo]()
$392
This Southwest deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/115:35 pm
MCI
- PIT
1 stop4h 35m
Southwest
Sat 5/1612:05 pm
PIT
- MCI
2 stops9h 25m
Southwest
Deal found 4/13![Southwest logo]()
$379
This United Airlines deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/206:56 pm
MCI
- PIT
1 stop4h 03m
United Airlines
Tue 5/266:10 am
PIT
- MCI
2 stops10h 50m
United Airlines
Deal found 4/14![United Airlines logo]()
$392
This Delta deal was found by Cheapflights users on 4/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/186:45 pm
SGF
- PIT
1 stop4h 37m
Delta
Sun 9/206:05 pm
PIT
- SGF
1 stop5h 24m
Delta
Deal found 4/18![Delta logo]()
$482
This Southwest deal was found by Cheapflights users on 4/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/2210:25 am
STL
- PIT
Nonstop1h 40m
Southwest
Thu 9/247:00 am
PIT
- STL
Nonstop1h 45m
Southwest
Deal found 4/18![Southwest logo]()
$381
This United Airlines deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/2911:30 am
COU
- PIT
1 stop4h 34m
United Airlines
Wed 9/27:00 am
PIT
- COU
1 stop4h 55m
United Airlines
Deal found 4/15![United Airlines logo]()
$398
This Southwest deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/125:35 pm
STL
- PIT
1 stop4h 30m
Southwest
Sun 6/147:00 am
PIT
- STL
Nonstop1h 45m
Southwest
Deal found 4/17![Southwest logo]()
$393
Last-minute flights from Missouri to PittsburghDiscover last-minute flight deals from Missouri to Pittsburgh. Data last updated April 19, 2026 and is based on user searches.
Discover last-minute flight deals from Missouri to Pittsburgh. Data last updated April 19, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/73:33 pm
STL
- PIT
2 stops26h 47m
Multiple Airlines
Sun 5/104:58 pm
PIT
- STL
1 stop8h 23m
Multiple Airlines
Deal found 4/13![Multiple Airlines logo]()
$258
This Trip.com deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/84:19 pm
STL
- PIT
1 stop26h 01m
Frontier
Sun 5/108:05 pm
PIT
- STL
1 stop29h 16m
Frontier
Deal found 4/13![Frontier logo]()
$231
This Kiwi.com deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/810:35 am
MCI
- PIT
1 stop7h 45m
Multiple Airlines
Sat 5/98:15 pm
PIT
- MCI
1 stop14h 14m
Multiple Airlines
Deal found 4/14![Multiple Airlines logo]()
$238
This Delta deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/96:00 am
STL
- PIT
1 stop5h 44m
Delta
Mon 5/117:50 pm
PIT
- STL
1 stop5h 09m
Delta
Deal found 4/16![Delta logo]()
$235
This Southwest deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/96:55 pm
STL
- PIT
Nonstop1h 35m
Southwest
Mon 5/118:10 pm
PIT
- STL
1 stop4h 05m
Southwest
Deal found 4/16![Southwest logo]()
$251
This Southwest deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/1310:15 am
STL
- PIT
Nonstop1h 40m
Southwest
Wed 5/207:10 pm
PIT
- STL
Nonstop1h 50m
Southwest
Deal found 4/15![Southwest logo]()
$217
This American Airlines deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/135:51 am
STL
- PIT
1 stop9h 57m
American Airlines
Wed 5/209:19 am
PIT
- STL
1 stop7h 41m
American Airlines
Deal found 4/15![American Airlines logo]()
$223
This Kiwi.com deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/1410:35 am
MCI
- PIT
1 stop21h 14m
Multiple Airlines
Fri 5/154:58 pm
PIT
- MCI
1 stop17h 31m
Multiple Airlines
Deal found 4/14![Multiple Airlines logo]()
$286
This Kiwi.com deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/1510:35 am
MCI
- PIT
1 stop28h 28m
Multiple Airlines
Sun 5/178:15 pm
PIT
- MCI
1 stop14h 14m
Multiple Airlines
Deal found 4/14![Multiple Airlines logo]()
$258
This Delta deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/216:45 am
STL
- PIT
1 stop3h 28m
Delta
Mon 5/256:25 pm
PIT
- STL
1 stop6h 34m
Delta
Deal found 4/14![Delta logo]()
$255
This Frontier deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/284:19 pm
STL
- PIT
1 stop26h 01m
Frontier
Mon 6/18:15 pm
PIT
- STL
1 stop28h 42m
Frontier
Deal found 4/14![Frontier logo]()
$181
This Southwest deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/2810:15 am
STL
- PIT
Nonstop1h 40m
Southwest
Mon 6/18:40 am
PIT
- STL
1 stop5h 15m
Southwest
Deal found 4/14![Southwest logo]()
$250
One-way flights from Missouri to PittsburghSearch for one-way flight options from Missouri to Pittsburgh. Find affordable one-way fares based on user searches. Data last updated April 19, 2026.
Search for one-way flight options from Missouri to Pittsburgh. Find affordable one-way fares based on user searches. Data last updated April 19, 2026.
This Kiwi.com deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/144:19 pm
STL
- PIT
1 stop15h 30m
Frontier
Deal found 4/14![Frontier logo]()
$91
This Southwest deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/1410:15 am
STL
- PIT
Nonstop1h 40m
Southwest
Deal found 4/15![Southwest logo]()
$109
This Kiwi.com deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/135:27 pm
STL
- PIT
2 stops27h 40m
Multiple Airlines
Deal found 4/14![Multiple Airlines logo]()
$111
This American Airlines deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/166:00 am
STL
- PIT
1 stop8h 04m
American Airlines
Deal found 4/14![American Airlines logo]()
$117
This Delta deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/141:27 pm
STL
- PIT
1 stop4h 28m
Delta
Deal found 4/16![Delta logo]()
$118
This Southwest deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/1210:15 am
STL
- PIT
Nonstop1h 40m
Southwest
Deal found 4/14![Southwest logo]()
$119
This Kiwi.com deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/810:35 am
MCI
- PIT
1 stop7h 45m
Multiple Airlines
Deal found 4/14![Multiple Airlines logo]()
$119
This Trip.com deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/234:59 pm
STL
- PIT
1 stop15h 00m
Frontier
Deal found 4/15![Frontier logo]()
$121
This Southwest deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/163:15 pm
STL
- PIT
2 stops6h 10m
Southwest
Deal found 4/17![Southwest logo]()
$123
This Kiwi.com deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/196:33 pm
STL
- PIT
2 stops22h 07m
Multiple Airlines
Deal found 4/17![Multiple Airlines logo]()
$125
This Kiwi.com deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/105:13 pm
STL
- PIT
2 stops28h 13m
Multiple Airlines
Deal found 4/14![Multiple Airlines logo]()
$126
This Kiwi.com deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/1510:35 am
MCI
- PIT
1 stop28h 28m
Spirit Airlines
Deal found 4/17![Spirit Airlines logo]()
$139
Find flight deals from Missouri to Pittsburgh
Keep the following information in mind while searching for Missouri to Pittsburgh flight deals. Data was last updated April 19, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $181 (Frontier) |
One-way from | $91 (Kiwi.com) |
Popular in | July |
Cheapest in | December |
Average price | $327 |
Good round-trip deal | $350 or less |
Good one-way deal | $184 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Missouri to Pittsburgh that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 19, 2026.
Use the filters below to find and compare flights from Missouri to Pittsburgh that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
St. LouisPittsburgh
STL - PIT
STLPIT
Lambert-St Louis
Wed 5/13
7:35 am-12:50 pm
1 stop4h 15m
Pittsburgh
Wed 5/20
7:10 pm-8:00 pm
Nonstop1h 50m
$226
St. LouisPittsburgh
STL - PIT
STLPIT
Lambert-St Louis
Sat 5/9
6:00 am-12:44 pm
1 stop5h 44m
Pittsburgh
Mon 5/11
7:50 pm-11:59 pm
1 stop5h 09m
$235
St. LouisPittsburgh
STL - PIT
STLPIT
Lambert-St Louis
Mon 5/11
10:15 am-12:55 pm
Nonstop1h 40m
Pittsburgh
Mon 5/18
6:55 am-7:45 am
Nonstop1h 50m
$265
St. LouisPittsburgh
STL - PIT
STLPIT
Lambert-St Louis
Tue 6/16
3:15 pm-10:25 pm
2 stops6h 10m
Pittsburgh
Tue 6/23
5:10 am-12:35 pm
2 stops8h 25m
$297
Kansas CityPittsburgh
MCI - PIT
MCIPIT
Kansas City
Tue 6/9
4:10 pm-12:40 am
1 stop7h 30m
Pittsburgh
Tue 6/23
3:55 pm-10:00 pm
1 stop7h 05m
$307
St. LouisPittsburgh
STL - PIT
STLPIT
Lambert-St Louis
Fri 8/21
5:00 am-9:54 am
1 stop3h 54m
Pittsburgh
Tue 8/25
7:28 pm-11:37 pm
1 stop5h 09m
$308
Kansas CityPittsburgh
MCI - PIT
MCIPIT
Kansas City
Tue 5/12
2:10 pm-8:45 pm
2 stops5h 35m
Pittsburgh
Tue 5/19
7:10 pm-10:00 pm
1 stop3h 50m
$312
St. LouisPittsburgh
STL - PIT
STLPIT
Lambert-St Louis
Fri 8/21
10:10 am-5:05 pm
1 stop5h 55m
Pittsburgh
Tue 8/25
6:40 am-7:20 am
Nonstop1h 40m
$315
ColumbiaPittsburgh
COU - PIT
COUPIT
Columbia Regional
Mon 7/13
11:23 am-5:05 pm
1 stop4h 42m
Pittsburgh
Sun 7/19
6:16 pm-12:33 am
1 stop7h 17m
$318
ColumbiaPittsburgh
COU - PIT
COUPIT
Columbia Regional
Fri 8/21
8:00 am-1:04 pm
1 stop4h 04m
Pittsburgh
Tue 8/25
6:10 am-2:30 pm
2 stops9h 20m
$324
Showing 1-10 of 54 resultsSorted by cheapest first
Best time to book a flight from Missouri to Pittsburgh
Have a flexible travel schedule? Discover the best time to fly to Pittsburgh from Missouri with our price prediction graph.
STL-PIT
SGF-PIT
COU-PIT
MCI-PIT
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Missouri to Pittsburgh
USMO-PIT
STL-PIT
SGF-PIT
COU-PIT
MCI-PIT
What is the cheapest month to book a flight from Missouri to Pittsburgh?
Currently, October is the cheapest month in which you can book a flight from Missouri to Pittsburgh (average of $76). Flying from Missouri to Pittsburgh in March is currently the most expensive (average of $299). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from MO to PIT?
Find hourly flight availability from Missouri to Pittsburgh. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 19, 2026.
It’s optimal to fly from Missouri to Pittsburgh in the afternoon. By choosing this option you can save up to 47% on the cost of your flight, compared to a flight in the evening.
How much does it cost to fly round-trip from Missouri to Pittsburgh?
Related info for your journey
Find useful and relevant information for your journey from Missouri to Pittsburgh. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Pittsburgh?
Book flights to Pittsburgh if you plan to visit one of these locationsMars
Chester
Steubenville
Washington
Monroeville
Wexford
Belle Vernon
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
Other flight options
Pittsburgh flight routes
Popular flights
Top destinations
Alternative routes for Missouri to Pittsburgh
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Pittsburgh by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Missouri to Pittsburgh by cabin class
Find flights from Missouri to Pittsburgh, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Missouri and Pittsburgh flights
Browse other Missouri and Pittsburgh flight options. Last updated on April 19, 2026.
Other flights to Pittsburgh
Explore flights to Pittsburgh departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on April 19, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Missouri to Pittsburgh flights
Consider these flights traveling from Missouri to Pittsburgh.
Top 4 airlines flying from Missouri to Pittsburgh
Discover the top 4 airlines that operate flights from Missouri to Pittsburgh. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 19, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$208 | Average$411 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$235 | Average$387 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$248 | Average$399 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$248 | Average$486 | FlexibilityNo cancel fee | On-timeN/A |