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Panama

$188+ Cheap flights from Louisville (SDF) to Panama

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/26. Fares are subject to change and may not be available on all flights or dates of travel.
SDF — PTY
Aug 23 — Aug 301
Sat 8/23
Sat 8/30
1 adult, Economy
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Cheap flight deals from Louisville to Panama

Keep the following information in mind while searching for Louisville to Panama flight deals. Data was last updated August 18, 2025.

Round-trip from

$415
(Delta)

One-way from

$188
(American Airlines)

Popular in

December

Cheapest in

September

Average price

$482
From Louisville Intl to Panama
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One-way flight from Louisville Intl to Panama
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Highest demand for flights based on searches. 10% potential increase in price ($62 potential increase over avg. RT price).
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Cheapest flight prices on average. 3% potential price decrease ($18 potential savings vs. average RT price).
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Average for round-trip flights in August 2025
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Find flight deals from Louisville to Panama

Cheapest flights from Louisville to Panama
Explore the most affordable flight options available from Louisville to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 18, 2025.

This Delta deal was found by Cheapflights users on 8/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/16:00 pmSDF - PTY
1 stop19h 50mDelta
Tue 9/92:05 pmPTY - SDF
1 stop8h 51mDelta
Deal found 8/15$415
This American Airlines deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/216:14 amSDF - PTY
1 stop9h 16mAmerican Airlines
Thu 8/283:30 pmPTY - SDF
1 stop7h 55mAmerican Airlines
Deal found 8/16$423
This United Airlines deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/219:40 amSDF - PTY
1 stop9h 57mUnited Airlines
Mon 8/253:30 pmPTY - SDF
2 stops24h 46mUnited Airlines
Deal found 8/17$428
This United Airlines deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/87:15 amSDF - PTY
1 stop12h 22mUnited Airlines
Sat 10/1110:00 amPTY - SDF
1 stop10h 54mUnited Airlines
Deal found 8/17$430
This United Airlines deal was found by Cheapflights users on 8/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/196:15 amSDF - PTY
1 stop8h 35mUnited Airlines
Thu 8/213:30 pmPTY - SDF
1 stop21h 00mUnited Airlines
Deal found 8/15$432
This United Airlines deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/119:40 amSDF - PTY
1 stop9h 57mUnited Airlines
Sun 9/213:30 pmPTY - SDF
2 stops17h 32mUnited Airlines
Deal found 8/16$437
This United Airlines deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/48:45 amSDF - PTY
2 stops10h 52mUnited Airlines
Sat 10/1110:00 amPTY - SDF
1 stop10h 54mUnited Airlines
Deal found 8/16$444
This United Airlines deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/219:40 amSDF - PTY
1 stop9h 57mUnited Airlines
Sat 8/233:30 pmPTY - SDF
2 stops24h 46mUnited Airlines
Deal found 8/17$448
This United Airlines deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/69:15 amSDF - PTY
1 stop10h 23mUnited Airlines
Mon 11/108:55 amPTY - SDF
1 stop13h 02mUnited Airlines
Deal found 8/17$461
This American Airlines deal was found by Cheapflights users on 8/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/18:06 pmSDF - PTY
2 stops19h 24mAmerican Airlines
Tue 9/91:45 pmPTY - SDF
1 stop9h 13mAmerican Airlines
Deal found 8/15$470

Cheapflights Fare Finder

 
Customize your flight search to find flights from Louisville to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 18, 2025.
Use the filters below to find and compare flights from Louisville to Panama that are best for you.

Fly from

Louisville

Fly to

Panama

Route

Depart

Return

Price

LouisvillePanama City

SDF - PTY

SDFPTY

Louisville Intl

Mon 9/1

6:00 pm-12:50 pm

1 stop19h 50m

Panama City Tocumen Intl

Tue 9/9

2:05 pm-11:56 pm

1 stop8h 51m

$415

LouisvillePanama City

SDF - PTY

SDFPTY

Louisville Intl

Wed 10/8

7:15 am-6:37 pm

1 stop12h 22m

Panama City Tocumen Intl

Sat 10/11

10:00 am-9:54 pm

1 stop10h 54m

$430

LouisvillePanama City

SDF - PTY

SDFPTY

Louisville Intl

Thu 11/6

7:31 pm-1:36 pm

2 stops18h 05m

Panama City Tocumen Intl

Mon 11/10

2:43 pm-11:39 pm

1 stop8h 56m

$435

LouisvillePanama City

SDF - PTY

SDFPTY

Louisville Intl

Wed 10/8

6:23 pm-2:03 pm

2 stops20h 40m

Panama City Tocumen Intl

Sat 10/11

3:15 pm-11:52 am

2 stops19h 37m

$435

LouisvillePanama City

SDF - PTY

SDFPTY

Louisville Intl

Thu 9/11

7:20 am-6:37 pm

2 stops12h 17m

Panama City Tocumen Intl

Sun 9/21

3:30 pm-10:02 am

2 stops17h 32m

$437

LouisvillePanama City

SDF - PTY

SDFPTY

Louisville Intl

Sat 10/4

8:45 am-6:37 pm

2 stops10h 52m

Panama City Tocumen Intl

Sat 10/11

10:00 am-9:54 pm

1 stop10h 54m

$444

LouisvillePanama City

SDF - PTY

SDFPTY

Louisville Intl

Thu 11/6

9:15 am-7:38 pm

1 stop10h 23m

Panama City Tocumen Intl

Mon 11/10

8:55 am-9:57 pm

1 stop13h 02m

$461

LouisvillePanama City

SDF - PTY

SDFPTY

Louisville Intl

Fri 9/26

6:44 pm-2:31 pm

2 stops20h 47m

$188

LouisvillePanama City

SDF - PTY

SDFPTY

Louisville Intl

Fri 9/26

10:14 am-9:10 pm

3 stops35h 56m

$258

Flights are sorted by cheapest round-trip flights first.

Deals found on 8/17

Best time to book a flight from Louisville to Panama

Have a flexible travel schedule? Discover the best time to fly to Panama from Louisville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Louisville to Panama

What is the cheapest month to book a flight from Louisville to Panama?

Currently, October is the cheapest month in which you can book a flight from Louisville to Panama (average of $478). Flying from Louisville to Panama in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SDF to PA?

Find hourly flight availability from Louisville to Panama. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated August 18, 2025.

When flying from Louisville to Panama, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Reviews of airlines servicing Panama

Get insights into the airlines that provide service to Panama. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama. Reviews last updated August 18, 2025.
Read through reviews of airlines operating flights from Louisville to Panama, such as Delta, United Airlines, and American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,981 reviews

Boarding

8.2

Food

7.3

Crew

8.5

Overall

8.0

Entertainment

7.9

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,981 reviews
Delta
8.0
Very good
7,981 reviews

Boarding

8.2

Food

7.3

Crew

8.5

Overall

8.0

Entertainment

7.9

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
United Airlines
7.4
Good
8,925 reviews
Delta
8.0
Very good
7,981 reviews

Boarding

8.2

Food

7.3

Crew

8.5

Overall

8.0

Entertainment

7.9

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,981 reviews

Boarding

8.2

Food

7.3

Crew

8.5

Overall

8.0

Entertainment

7.9

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from Louisville to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Louisville to Panama?

    Louisville Intl (SDF) is the airport you will fly out of if you book a flight from Louisville to Panama. It is only a 5.3 mi journey to Louisville Intl (SDF) from Louisville’s city center.

  • Can I find deals for flights from Louisville to Panama that include hotel bookings?

    Yes. In addition to deals on Louisville to Panama flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Louisville to Panama?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Louisville to Panama.

  • Can I find deals for business class flights from Louisville to Panama?

    Yes. Cheapflights offers flight deals from Louisville to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Louisville to Panama?

    Currently, October is the cheapest month in which you can book a flight from Louisville to Panama (average of $478). Flying from Louisville to Panama in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Louisville to Panama

See prices for flight routes from nearby airports that may be better suited for you.
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Top 3 airlines flying from Louisville to Panama

Discover the top 3 airlines that operate flights from Louisville to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 18, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$338Average$582FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$351Average$515FlexibilityNo cancel feeOn-time69%
DeltaCheapest$382Average$504FlexibilityNo cancel feeOn-timeN/A

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