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$248+ Cheap flights from Iowa to Panama

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/18. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — PTY
Jan 29 — Feb 51
Thu 1/29
Thu 2/5
1 adult, Economy
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Cheap flight deals from Iowa to Panama

Cheapest flights from Iowa to Panama
Explore the most affordable flight options available from Iowa to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 30, 2025.

This United Airlines deal was found by Cheapflights users on 12/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/296:46 pmDSM - PTY
2 stops18h 59mUnited Airlines
Mon 3/233:41 pmPTY - DSM
2 stops21h 42mUnited Airlines
Deal found 12/27$466
This United Airlines deal was found by Cheapflights users on 12/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/318:00 amCID - PTY
2 stops29h 45mUnited Airlines
Tue 3/34:41 pmPTY - CID
2 stops19h 03mUnited Airlines
Deal found 12/28$589
This Delta deal was found by Cheapflights users on 12/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/315:47 amCID - PTY
1 stop7h 10mDelta
Wed 3/43:15 pmPTY - CID
2 stops21h 23mDelta
Deal found 12/28$609
This Delta deal was found by Cheapflights users on 12/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/304:21 pmCID - PTY
2 stops26h 39mDelta
Fri 3/63:15 pmPTY - CID
2 stops32h 28mDelta
Deal found 12/28$691
This Delta deal was found by Cheapflights users on 12/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/305:47 amCID - PTY
1 stop13h 13mDelta
Tue 3/33:15 pmPTY - CID
2 stops21h 23mDelta
Deal found 12/28$846
This United Airlines deal was found by Cheapflights users on 12/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/308:00 amCID - PTY
2 stops29h 45mUnited Airlines
Tue 1/64:41 pmPTY - CID
2 stops29h 53mUnited Airlines
Deal found 12/29$849
This Kiwi.com deal was found by Cheapflights users on 12/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/296:44 pmCID - PTY
1 stop24h 35mMultiple Airlines
Thu 3/52:55 amPTY - CID
2 stops16h 14mMultiple Airlines
Deal found 12/28$852
This Kiwi.com deal was found by Cheapflights users on 12/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/296:44 pmCID - PTY
2 stops29h 16mMultiple Airlines
Thu 3/512:03 pmPTY - CID
1 stop31h 06mMultiple Airlines
Deal found 12/28$881
This Delta deal was found by Cheapflights users on 12/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/304:21 pmCID - PTY
2 stops20h 36mDelta
Mon 3/23:15 pmPTY - CID
2 stops21h 23mDelta
Deal found 12/28$889
This Delta deal was found by Cheapflights users on 12/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/304:21 pmCID - PTY
2 stops20h 36mDelta
Sat 2/283:15 pmPTY - CID
2 stops21h 23mDelta
Deal found 12/28$914
This Delta deal was found by Cheapflights users on 12/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/304:21 pmCID - PTY
2 stops20h 36mDelta
Sun 3/13:15 pmPTY - CID
2 stops32h 28mDelta
Deal found 12/28$940
This Kiwi.com deal was found by Cheapflights users on 12/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/296:44 pmCID - PTY
1 stop24h 35mMultiple Airlines
Wed 3/49:33 pmPTY - CID
2 stops22h 30mMultiple Airlines
Deal found 12/28$955

Find flight deals from Iowa to Panama

Keep the following information in mind while searching for Iowa to Panama flight deals. Data was last updated December 30, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$462
(United Airlines)

One-way from

$248
(United Airlines)

Popular in

June

Cheapest in

September

Average price

$1,033
Provider with most accurate pricing for Des Moines-Panama City Tocumen Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Des Moines-Panama City Tocumen Intl flights.
Search Deals
From Iowa to Panama
Search Deals
One-way flight from Iowa to Panama
Search Deals
Highest demand for flights based on searches. 10% potential increase in price ($70 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 7% potential price decrease ($42 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Iowa to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 30, 2025.
Use the filters below to find and compare flights from Iowa to Panama that are best for you.

Fly from

Iowa

Fly to

Panama

Route

Depart

Return

Price

Des MoinesPanama City

DSM - PTY

DSMPTY

Des Moines

Thu 2/26

7:52 am-5:07 pm

1 stop8h 15m

Panama City Tocumen Intl

Sat 3/7

8:55 am-10:44 pm

1 stop14h 49m

$462

Des MoinesPanama City

DSM - PTY

DSMPTY

Des Moines

Tue 2/24

7:52 am-5:07 pm

1 stop8h 15m

Panama City Tocumen Intl

Fri 3/6

11:35 am-10:44 pm

1 stop12h 09m

$462

Des MoinesPanama City

DSM - PTY

DSMPTY

Des Moines

Thu 1/1

6:00 am-3:54 pm

1 stop8h 54m

Panama City Tocumen Intl

Wed 4/1

3:51 pm-1:17 pm

2 stops21h 26m

$466

Des MoinesPanama City

DSM - PTY

DSMPTY

Des Moines

Tue 1/13

8:10 am-5:07 pm

1 stop7h 57m

Panama City Tocumen Intl

Tue 1/20

4:41 pm-2:33 pm

2 stops22h 52m

$466

Des MoinesPanama City

DSM - PTY

DSMPTY

Des Moines

Mon 2/9

6:48 pm-5:07 pm

2 stops21h 19m

Panama City Tocumen Intl

Fri 2/13

8:55 am-10:20 pm

1 stop14h 25m

$466

Des MoinesPanama City

DSM - PTY

DSMPTY

Des Moines

Tue 2/10

8:00 am-7:38 pm

2 stops10h 38m

Panama City Tocumen Intl

Tue 2/17

4:41 pm-2:27 pm

2 stops22h 46m

$466

Des MoinesPanama City

DSM - PTY

DSMPTY

Des Moines

Tue 1/13

8:10 am-5:07 pm

1 stop7h 57m

Panama City Tocumen Intl

Wed 1/21

4:41 pm-2:33 pm

2 stops22h 52m

$466

Cedar RapidsPanama City

CID - PTY

CIDPTY

Cedar Rapids

Mon 3/30

5:20 am-1:03 pm

1 stop7h 43m

Panama City Tocumen Intl

Thu 4/2

2:28 pm-10:19 pm

1 stop7h 51m

$522

OmahaPanama City

OMA - PTY

OMAPTY

Omaha Eppley Airfield

Mon 2/23

8:15 am-7:38 pm

1 stop10h 23m

Panama City Tocumen Intl

Tue 3/3

8:55 am-10:27 pm

1 stop14h 32m

$522

Cedar RapidsPanama City

CID - PTY

CIDPTY

Cedar Rapids

Sun 3/29

11:51 am-1:03 pm

2 stops25h 12m

Panama City Tocumen Intl

Thu 4/2

2:28 pm-10:19 pm

1 stop7h 51m

$526

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/28

Showing 1-10 of 36 results
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Best time to book a flight from Iowa to Panama

Have a flexible travel schedule? Discover the best time to fly to Panama from Iowa with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Iowa to Panama

What is the cheapest month to book a flight from Iowa to Panama?

Currently, April is the cheapest month in which you can book a flight from Iowa to Panama (average of $411). Flying from Iowa to Panama in December is currently the most expensive (average of $729). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from Iowa to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Iowa to Panama?

    United Airlines, Delta, and American Airlines can get you from Iowa to Panama in just under 7h 43m. Your travel time can differ by up to 11h 36m. Airlines will cover a distance of 2386 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • Can I find deals for flights from Iowa to Panama that include hotel bookings?

    Yes. In addition to deals on Iowa to Panama flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Iowa to Panama?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Iowa to Panama.

  • Can I find deals for business class flights from Iowa to Panama?

    Yes. Cheapflights offers flight deals from Iowa to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Iowa to Panama?

    Currently, April is the cheapest month in which you can book a flight from Iowa to Panama (average of $411). Flying from Iowa to Panama in December is currently the most expensive (average of $729). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Iowa to Panama

See prices for flight routes from nearby airports that may be better suited for you.
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Top 2 airlines flying from Iowa to Panama

Discover the top 2 airlines that operate flights from Iowa to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 30, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$420Average$465FlexibilityNo cancel feeOn-time69%
DeltaCheapest$441Average$616FlexibilityNo cancel feeOn-timeN/A

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