How long is the flight from Iowa to Panama?

United Airlines and American Airlines can get you from Iowa to Panama in just under 10h 38m. Your travel time can differ by up to 9h 31m. Airlines will cover a distance of 2405 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

In terms of precipitation, rainfall in Panama ranges from 0.4 - 13.4 inches per month. October is typically the wettest month, when rainfall can reach 13.4 in. February is typically the driest time to visit Panama when rainfall is around 0.4 in.

If weather is an important factor for your trip to Panama, use this chart to help with planning. For those seeking warmer temperatures, February is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 78.8 F).

Can I find deals for flights from Iowa to Panama that include hotel bookings?

Yes. In addition to deals on Iowa to Panama flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Iowa to Panama?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Iowa to Panama.

Can I find deals for business class flights from Iowa to Panama?

Yes. Cheapflights offers flight deals from Iowa to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$198+ Flights from Iowa to Panama

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Cheap flight deals from Iowa to Panama

Cheapest flights from Iowa to Panama
Explore the most affordable flight options available from Iowa to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 23, 2025.

Mon 12/296:46 pmDSM - PTY

2 stops18h 59mUnited Airlines

Mon 3/233:41 pmPTY - DSM

2 stops21h 42mUnited Airlines

Deal found 12/22

$466

Mon 12/222:57 pmOMA - PTY

1 stop27h 41mUnited Airlines

Mon 12/298:55 amPTY - OMA

1 stop14h 27mUnited Airlines

Deal found 12/21

$659

Sat 12/273:00 pmCID - PTY

2 stops22h 45mUnited Airlines

Thu 1/14:41 pmPTY - CID

2 stops22h 33mUnited Airlines

Deal found 12/21

$847

Sat 12/275:47 amCID - PTY

1 stop7h 10mDelta

Thu 1/18:00 amPTY - CID

1 stop14h 28mDelta

Deal found 12/21

$1,605

Best flights from Iowa to Panama
Discover carefully curated flight deals from Iowa to Panama that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated December 23, 2025.

Wed 2/48:00 amDSM - PTY

2 stops10h 38mUnited Airlines

Wed 2/118:55 amPTY - DSM

1 stop14h 35mUnited Airlines

Deal found 12/22

$462

Mon 5/254:16 pmOMA - PTY

2 stops20h 09mAmerican Airlines

Tue 6/21:50 pmPTY - OMA

2 stops22h 38mAmerican Airlines

Deal found 12/21

$526

Tue 2/35:35 amCID - PTY

1 stop7h 20mDelta

Thu 3/53:15 pmPTY - CID

2 stops21h 23mDelta

Deal found 12/22

$566

Sun 1/118:10 amDSM - PTY

1 stop7h 57mUnited Airlines

Thu 1/2211:35 amPTY - DSM

1 stop11h 55mUnited Airlines

Deal found 12/22

$462

Thu 2/267:52 amDSM - PTY

1 stop8h 15mUnited Airlines

Sat 3/78:55 amPTY - DSM

1 stop14h 49mUnited Airlines

Deal found 12/19

$462

Tue 5/261:57 pmOMA - PTY

2 stops22h 28mAmerican Airlines

Tue 6/21:50 pmPTY - OMA

2 stops22h 52mAmerican Airlines

Deal found 12/21

$526

Tue 2/247:52 amDSM - PTY

1 stop8h 15mUnited Airlines

Fri 3/611:35 amPTY - DSM

1 stop12h 09mUnited Airlines

Deal found 12/21

$462

Sun 2/86:48 pmDSM - PTY

2 stops21h 19mUnited Airlines

Wed 2/254:41 pmPTY - DSM

2 stops22h 46mUnited Airlines

Deal found 12/21

$466

Tue 2/35:51 pmCID - PTY

2 stops18h 36mAmerican Airlines

Thu 3/54:05 pmPTY - CID

2 stops21h 30mAmerican Airlines

Deal found 12/21

$566

Tue 2/38:00 amDSM - PTY

2 stops10h 38mUnited Airlines

Tue 2/104:41 pmPTY - DSM

2 stops19h 14mUnited Airlines

Deal found 12/20

$466

Mon 12/296:46 pmDSM - PTY

2 stops18h 59mUnited Airlines

Mon 3/233:41 pmPTY - DSM

2 stops21h 42mUnited Airlines

Deal found 12/22

$466

Tue 5/265:15 pmOMA - PTY

2 stops20h 59mUnited Airlines

Tue 6/27:55 amPTY - OMA

1 stop11h 20mUnited Airlines

Deal found 12/21

$526

Wed 3/118:15 amOMA - PTY

1 stop7h 52mUnited Airlines

Mon 3/163:41 pmPTY - OMA

2 stops21h 04mUnited Airlines

Deal found 12/21

$526

Sun 2/151:50 pmOMA - PTY

2 stops23h 55mUnited Airlines

Thu 2/2611:35 amPTY - OMA

2 stops26h 05mUnited Airlines

Deal found 12/21

$526

Wed 2/188:00 amCID - PTY

2 stops10h 38mUnited Airlines

Fri 2/204:41 pmPTY - CID

2 stops19h 03mUnited Airlines

Deal found 12/20

$546

Tue 2/38:00 amCID - PTY

1 stop11h 35mUnited Airlines

Thu 3/57:55 amPTY - CID

1 stop12h 03mUnited Airlines

Deal found 12/21

$4,654

Last-minute flights from Iowa to Panama
Discover last-minute flight deals from Iowa to Panama. Data last updated December 23, 2025 and is based on user searches.

Mon 12/222:57 pmOMA - PTY

1 stop27h 41mUnited Airlines

Mon 12/298:55 amPTY - OMA

1 stop14h 27mUnited Airlines

Deal found 12/21

$659

Mon 12/296:46 pmDSM - PTY

2 stops23h 52mUnited Airlines

Mon 3/233:41 pmPTY - DSM

2 stops21h 42mUnited Airlines

Deal found 12/21

$508

Thu 1/15:39 pmDSM - PTY

2 stops19h 14mAmerican Airlines

Wed 4/13:13 pmPTY - DSM

2 stops19h 21mAmerican Airlines

Deal found 12/21

$466

Thu 1/13:00 pmDSM - PTY

1 stop22h 45mUnited Airlines

Wed 4/110:00 amPTY - DSM

1 stop12h 43mUnited Airlines

Deal found 12/22

$471

Mon 1/53:27 pmDSM - PTY

2 stops23h 04mAmerican Airlines

Wed 1/74:31 pmPTY - DSM

2 stops19h 19mAmerican Airlines

Deal found 12/22

$591

Mon 1/53:00 pmDSM - PTY

1 stop22h 45mUnited Airlines

Wed 1/74:41 pmPTY - DSM

2 stops22h 52mUnited Airlines

Deal found 12/22

$619

Mon 1/55:15 pmOMA - PTY

2 stops22h 52mUnited Airlines

Sat 1/174:41 pmPTY - OMA

2 stops21h 03mUnited Airlines

Deal found 12/22

$626

Sun 1/118:10 amDSM - PTY

1 stop7h 57mUnited Airlines

Thu 1/2211:35 amPTY - DSM

1 stop11h 55mUnited Airlines

Deal found 12/22

$462

Wed 1/146:16 pmOMA - PTY

2 stops20h 22mAmerican Airlines

Wed 1/212:27 pmPTY - OMA

2 stops24h 03mAmerican Airlines

Deal found 12/20

$621

Wed 1/145:18 pmOMA - PTY

2 stops22h 49mUnited Airlines

Wed 1/2111:35 amPTY - OMA

1 stop8h 19mUnited Airlines

Deal found 12/21

$658

Fri 1/166:06 amOMA - PTY

1 stop12h 32mUnited Airlines

Sat 1/248:55 amPTY - OMA

1 stop14h 26mUnited Airlines

Deal found 12/22

$622

Sat 1/175:21 pmOMA - PTY

2 stops20h 24mUnited Airlines

Sat 1/244:41 pmPTY - OMA

2 stops24h 31mUnited Airlines

Deal found 12/20

$606

One-way flights from Iowa to Panama
Search for one-way flight options from Iowa to Panama. Find affordable one-way fares based on user searches. Data last updated December 23, 2025.

Sun 2/88:10 amDSM - PTY

1 stop7h 57mUnited Airlines

Deal found 12/19

$198

Mon 1/268:15 amOMA - PTY

1 stop10h 23mUnited Airlines

Deal found 12/21

$248

Sun 2/82:58 pmDSM - PTY

3 stops32h 42mMultiple Airlines

Deal found 12/19

$253

Thu 3/52:02 pmDSM - PTY

2 stops24h 13mAmerican Airlines

Deal found 12/21

$265

Tue 1/65:40 pmOMA - PTY

2 stops20h 51mAmerican Airlines

Deal found 12/21

$268

Sun 1/111:11 pmOMA - PTY

3 stops47h 49mMultiple Airlines

Deal found 12/21

$274

Sun 1/113:00 pmOMA - PTY

1 stop27h 38mUnited Airlines

Deal found 12/21

$284

Sat 1/106:06 amOMA - PTY

1 stop10h 01mUnited Airlines

Deal found 12/21

$288

Tue 12/305:35 amOMA - PTY

1 stop13h 25mDelta

Deal found 12/22

$291

Thu 1/151:50 pmOMA - PTY

2 stops23h 55mUnited Airlines

Deal found 12/21

$294

Tue 12/307:34 pmOMA - PTY

2 stops19h 20mAmerican Airlines

Deal found 12/22

$297

Sun 3/152:02 pmDSM - PTY

2 stops22h 20mAmerican Airlines

Deal found 12/21

$299

Find flight deals from Iowa to Panama

Most accurate provider	eDreams 3 stars
Most trusted provider	eDreams 3 stars
Round-trip from	$453 (United Airlines)
One-way from	$198 (United Airlines)
Popular in	June
Cheapest in	September
Average price	$1,033

Provider with most accurate pricing for Des Moines-Panama City Tocumen Intl flight deals.

Search Deals

Provider most trusted by Cheapflights users for Des Moines-Panama City Tocumen Intl flights.

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From Iowa to Panama

Search Deals

One-way flight from Iowa to Panama

Search Deals

Highest demand for flights based on searches. 10% potential increase in price ($70 potential increase over avg. RT price).

Search Deals

Cheapest flight prices on average. 7% potential price decrease ($42 potential savings vs. average RT price).

Search Deals

Average for round-trip flights in December 2025

Search Deals

Fly from

Fly to

Route

Depart

Return

Price

Des MoinesPanama City

DSM - PTY

DSMPTY

Des Moines

Wed 2/4

8:00 am-7:38 pm

2 stops10h 38m

Panama City Tocumen Intl

Wed 2/11

8:55 am-10:30 pm

1 stop14h 35m

$462

Des MoinesPanama City

DSM - PTY

DSMPTY

Des Moines

Sun 1/11

8:10 am-5:07 pm

1 stop7h 57m

Panama City Tocumen Intl

Thu 1/22

11:35 am-10:30 pm

1 stop11h 55m

$462

Des MoinesPanama City

DSM - PTY

DSMPTY

Des Moines

Thu 2/26

7:52 am-5:07 pm

1 stop8h 15m

Panama City Tocumen Intl

Sat 3/7

8:55 am-10:44 pm

1 stop14h 49m

$462

Des MoinesPanama City

DSM - PTY

DSMPTY

Des Moines

Tue 2/24

7:52 am-5:07 pm

1 stop8h 15m

Panama City Tocumen Intl

Fri 3/6

11:35 am-10:44 pm

1 stop12h 09m

$462

Des MoinesPanama City

DSM - PTY

DSMPTY

Des Moines

Sun 2/8

6:48 pm-5:07 pm

2 stops21h 19m

Panama City Tocumen Intl

Wed 2/25

4:41 pm-2:27 pm

2 stops22h 46m

$466

Des MoinesPanama City

DSM - PTY

DSMPTY

Des Moines

Tue 2/3

8:00 am-7:38 pm

2 stops10h 38m

Panama City Tocumen Intl

Tue 2/10

4:41 pm-10:55 am

2 stops19h 14m

$466

Des MoinesPanama City

DSM - PTY

DSMPTY

Des Moines

Mon 12/29

6:46 pm-2:45 pm

2 stops18h 59m

Panama City Tocumen Intl

Mon 3/23

3:41 pm-1:23 pm

2 stops21h 42m

$466

OmahaPanama City

OMA - PTY

OMAPTY

Omaha Eppley Airfield

Mon 5/25

4:16 pm-12:25 pm

2 stops20h 09m

Panama City Tocumen Intl

Tue 6/2

1:50 pm-12:28 pm

2 stops22h 38m

$526

OmahaPanama City

OMA - PTY

OMAPTY

Omaha Eppley Airfield

Tue 5/26

1:57 pm-12:25 pm

2 stops22h 28m

Panama City Tocumen Intl

Tue 6/2

1:50 pm-12:42 pm

2 stops22h 52m

$526

OmahaPanama City

OMA - PTY

OMAPTY

Omaha Eppley Airfield

Tue 5/26

5:15 pm-2:14 pm

2 stops20h 59m

Panama City Tocumen Intl

Tue 6/2

7:55 am-7:15 pm

1 stop11h 20m

$526

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/19

Showing 1-10 of 32 results

Best time to book a flight from Iowa to Panama

Have a flexible travel schedule? Discover the best time to fly to Panama from Iowa with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Iowa to Panama

What is the cheapest month to book a flight from Iowa to Panama?

Currently, April is the cheapest month in which you can book a flight from Iowa to Panama (average of $411). Flying from Iowa to Panama in December is currently the most expensive (average of $729). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from IA to PA?

It’s typically best to fly out from Iowa to Panama at noon. Doing so could potentially save you 58% on the flight price compared to flying in the morning, which is usually more expensive.

Related info for your journey

How long is the flight from Iowa to Panama?
United Airlines and American Airlines can get you from Iowa to Panama in just under 10h 38m. Your travel time can differ by up to 9h 31m. Airlines will cover a distance of 2405 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.
Can I find deals for flights from Iowa to Panama that include hotel bookings?
Yes. In addition to deals on Iowa to Panama flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Iowa to Panama?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Iowa to Panama.
Can I find deals for business class flights from Iowa to Panama?
Yes. Cheapflights offers flight deals from Iowa to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Iowa to Panama?
Currently, April is the cheapest month in which you can book a flight from Iowa to Panama (average of $411). Flying from Iowa to Panama in December is currently the most expensive (average of $729). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Alternative routes for Iowa to Panama

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Top 2 airlines flying from Iowa to Panama

Airline	Cheapest	Average	Flexibility	On-time
United Airlines	Cheapest$420	Average$485	FlexibilityNo cancel fee	On-time69%
Delta	Cheapest$441	Average$616	FlexibilityNo cancel fee	On-timeN/A

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$198+ Cheap flights from Iowa to Panama

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/8. Fares are subject to change and may not be available on all flights or dates of travel.

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Cheap flight deals from Iowa to Panama

Cheapest flights from Iowa to PanamaExplore the most affordable flight options available from Iowa to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 23, 2025.

Explore the most affordable flight options available from Iowa to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 23, 2025.

Find flight deals from Iowa to Panama

Keep the following information in mind while searching for Iowa to Panama flight deals. Data was last updated December 23, 2025.

Most accurate provider

Most trusted provider

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Cheapflights Fare Finder

Use the filters below to find and compare flights from Iowa to Panama that are best for you.

Best time to book a flight from Iowa to Panama

Have a flexible travel schedule? Discover the best time to fly to Panama from Iowa with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Iowa to Panama

What is the cheapest month to book a flight from Iowa to Panama?

What is the cheapest time of day to fly from IA to PA?

Find hourly flight availability from Iowa to Panama. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 23, 2025.

Related info for your journey

Find useful and relevant information for your journey from Iowa to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

How long is the flight from Iowa to Panama?

Can I find deals for flights from Iowa to Panama that include hotel bookings?

How can I find direct flights from Iowa to Panama?

Can I find deals for business class flights from Iowa to Panama?

What is the cheapest month to book a flight from Iowa to Panama?

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Iowa to Panama

See prices for flight routes from nearby airports that may be better suited for you.

Top 2 airlines flying from Iowa to Panama

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Cheapest flights from Iowa to Panama
Explore the most affordable flight options available from Iowa to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 23, 2025.