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Panama

$248+ Cheap flights from Iowa to Panama

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/8. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — PTY
Nov 16 — Nov 231
Sun 11/16
Sun 11/23
1 adult, Economy
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Find flight deals from Iowa to Panama

Cheapest flights from Iowa to Panama
Explore the most affordable flight options available from Iowa to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 17, 2025.

This Delta deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/295:35 amDSM - PTY
1 stop13h 24mDelta
Sat 12/68:05 amPTY - DSM
1 stop15h 29mDelta
Deal found 10/15$462
This United Airlines deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/246:05 amDSM - PTY
1 stop12h 33mUnited Airlines
Thu 11/274:41 pmPTY - DSM
1 stop30h 39mUnited Airlines
Deal found 10/16$471
This United Airlines deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/309:44 pmDSM - PTY
2 stops20h 54mUnited Airlines
Sun 12/74:41 pmPTY - DSM
1 stop30h 48mUnited Airlines
Deal found 10/16$475
This United Airlines deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/85:21 pmCID - PTY
2 stops20h 24mUnited Airlines
Tue 1/274:41 pmPTY - CID
2 stops19h 06mUnited Airlines
Deal found 10/15$526
This United Airlines deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/136:00 amOMA - PTY
1 stop12h 38mUnited Airlines
Wed 1/144:41 pmPTY - OMA
2 stops21h 03mUnited Airlines
Deal found 10/16$546
This Delta deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/85:50 amCID - PTY
1 stop7h 31mDelta
Fri 1/303:27 pmPTY - CID
2 stops23h 40mDelta
Deal found 10/15$546
This American Airlines deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/293:31 pmDSM - PTY
2 stops21h 12mAmerican Airlines
Sat 12/64:43 pmPTY - DSM
2 stops20h 40mAmerican Airlines
Deal found 10/15$559
This United Airlines deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/309:05 pmOMA - PTY
2 stops21h 33mUnited Airlines
Sun 12/78:55 amPTY - OMA
1 stop10h 53mUnited Airlines
Deal found 10/16$566
This United Airlines deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/165:26 pmCID - PTY
2 stops20h 19mUnited Airlines
Wed 11/194:41 pmPTY - CID
2 stops29h 48mUnited Airlines
Deal found 10/16$566
This Delta deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/165:54 amCID - PTY
1 stop7h 18mDelta
Wed 11/193:37 pmPTY - CID
1 stop8h 01mDelta
Deal found 10/16$582
This United Airlines deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/296:00 amOMA - PTY
1 stop12h 38mUnited Airlines
Sat 12/68:55 amPTY - OMA
2 stops12h 04mUnited Airlines
Deal found 10/15$586
This United Airlines deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/296:46 pmDSM - PTY
2 stops23h 52mUnited Airlines
Mon 3/2310:55 pmPTY - DSM
2 stops15h 32mUnited Airlines
Deal found 10/16$586

Cheap flight deals from Iowa to Panama

Keep the following information in mind while searching for Iowa to Panama flight deals. Data was last updated October 17, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$462
(Delta)

One-way from

$248
(United Airlines)

Popular in

June

Cheapest in

December

Average price

$583
Provider with most accurate pricing for Des Moines-Panama City Tocumen Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Des Moines-Panama City Tocumen Intl flights.
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From Iowa to Panama
Search Deals
One-way flight from Iowa to Panama
Search Deals
Highest demand for flights based on searches. 15% potential increase in price ($106 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 8% potential price decrease ($44 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in October 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Iowa to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 17, 2025.
Use the filters below to find and compare flights from Iowa to Panama that are best for you.

Fly from

Iowa

Fly to

Panama

Route

Depart

Return

Price

Des MoinesPanama City

DSM - PTY

DSMPTY

Des Moines

Sat 11/29

5:35 am-7:59 pm

1 stop13h 24m

Panama City Tocumen Intl

Sat 12/6

8:05 am-10:34 pm

1 stop15h 29m

$462

Des MoinesPanama City

DSM - PTY

DSMPTY

Des Moines

Tue 2/24

8:00 am-7:38 pm

1 stop10h 38m

Panama City Tocumen Intl

Fri 3/6

8:55 am-10:36 pm

1 stop14h 41m

$462

Des MoinesPanama City

DSM - PTY

DSMPTY

Des Moines

Sun 11/30

9:44 pm-2:45 pm

2 stops16h 01m

Panama City Tocumen Intl

Sun 12/7

11:55 pm-2:20 pm

2 stops15h 25m

$466

Des MoinesPanama City

DSM - PTY

DSMPTY

Des Moines

Fri 2/13

6:45 pm-2:45 pm

2 stops19h 00m

Panama City Tocumen Intl

Sat 3/7

10:55 pm-1:27 pm

2 stops15h 32m

$466

Des MoinesPanama City

DSM - PTY

DSMPTY

Des Moines

Mon 1/12

8:00 am-7:38 pm

2 stops10h 38m

Panama City Tocumen Intl

Thu 1/15

4:41 pm-2:33 pm

2 stops22h 52m

$466

OmahaPanama City

OMA - PTY

OMAPTY

Omaha Eppley Airfield

Wed 3/11

6:00 am-6:38 pm

1 stop12h 38m

Panama City Tocumen Intl

Mon 3/16

7:55 am-6:53 pm

1 stop10h 58m

$522

OmahaPanama City

OMA - PTY

OMAPTY

Omaha Eppley Airfield

Wed 2/4

1:50 pm-2:45 pm

2 stops23h 55m

Panama City Tocumen Intl

Tue 3/3

11:35 am-6:54 pm

1 stop8h 19m

$526

Cedar RapidsPanama City

CID - PTY

CIDPTY

Cedar Rapids

Sun 3/1

5:27 pm-2:45 pm

2 stops20h 18m

Panama City Tocumen Intl

Wed 3/4

11:35 am-10:33 am

2 stops23h 58m

$526

OmahaPanama City

OMA - PTY

OMAPTY

Omaha Eppley Airfield

Wed 3/11

6:13 pm-12:10 pm

2 stops17h 57m

Panama City Tocumen Intl

Mon 3/16

3:50 pm-12:42 pm

2 stops20h 52m

$546

Cedar RapidsPanama City

CID - PTY

CIDPTY

Cedar Rapids

Sun 3/1

5:45 am-2:02 pm

1 stop7h 17m

Panama City Tocumen Intl

Wed 3/4

3:27 pm-11:36 am

2 stops21h 09m

$546

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/15

Showing 1-10 of 22 results
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Best time to book a flight from Iowa to Panama

Have a flexible travel schedule? Discover the best time to fly to Panama from Iowa with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Iowa to Panama

What is the cheapest month to book a flight from Iowa to Panama?

Currently, December is the cheapest month in which you can book a flight from Iowa to Panama (average of $401). Flying from Iowa to Panama in March is currently the most expensive (average of $604). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from IA to PA?

Find hourly flight availability from Iowa to Panama. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 17, 2025.

It’s typically best to fly out from Iowa to Panama at noon. Doing so could potentially save you 60% on the flight price compared to flying in the morning, which is usually more expensive.

Related info for your journey

Find useful and relevant information for your journey from Iowa to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Iowa to Panama?

    Delta and United Airlines can get you from Iowa to Panama in just under 10h 38m. Your travel time can differ by up to 2h 46m. Airlines will cover a distance of 2405 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • Can I find deals for flights from Iowa to Panama that include hotel bookings?

    Yes. In addition to deals on Iowa to Panama flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Iowa to Panama?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Iowa to Panama.

  • Can I find deals for business class flights from Iowa to Panama?

    Yes. Cheapflights offers flight deals from Iowa to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Iowa to Panama?

    Currently, December is the cheapest month in which you can book a flight from Iowa to Panama (average of $401). Flying from Iowa to Panama in March is currently the most expensive (average of $604). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Iowa to Panama

See prices for flight routes from nearby airports that may be better suited for you.
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Top 3 airlines flying from Iowa to Panama

Discover the top 3 airlines that operate flights from Iowa to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 17, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$414Average$486FlexibilityNo cancel feeOn-time69%
DeltaCheapest$441Average$632FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$445Average$544FlexibilityNo cancel feeOn-time71%

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