$316+ Cheap flights from Iowa to Panama
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/10. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — PTY
Dec 12 — Dec 191
Round-trip
1 adult, Economy
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Find cheap flights from Iowa to Panama with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Iowa to Panama
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Best
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One-way
Cheapest flights from Iowa to PanamaExplore the most affordable flight options available from Iowa to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 12, 2026.
Explore the most affordable flight options available from Iowa to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 12, 2026.
This United Airlines deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/188:00 am -
1 stop10h 38m
Thu 11/268:55 am -
1 stop30h 25m
Deal found 11/8![United Airlines logo]()
$790
This United Airlines deal was found by Cheapflights users on 11/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/88:00 am -
1 stop8h 12m
Tue 1/128:55 am -
1 stop14h 35m
Deal found 11/7![United Airlines logo]()
$820
This United Airlines deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/256:45 pm -
2 stops24h 17m
Sun 12/68:55 am -
1 stop14h 26m
Deal found 11/10![United Airlines logo]()
$826
This American Airlines deal was found by Cheapflights users on 11/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/83:31 pm -
2 stops21h 42m
Tue 1/122:26 pm -
1 stop9h 33m
Deal found 11/7![American Airlines logo]()
$828
This American Airlines deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/205:01 am -
1 stop8h 33m
Sat 11/283:34 pm -
2 stops27h 53m
Deal found 11/11![American Airlines logo]()
$1,151
This United Airlines deal was found by Cheapflights users on 11/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/225:00 am -
2 stops11h 12m
Tue 12/2911:55 pm -
2 stops22h 28m
Deal found 11/7![United Airlines logo]()
$1,170
This United Airlines deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/235:00 am -
2 stops13h 38m
Wed 12/3011:35 am -
2 stops21h 20m
Deal found 11/8![United Airlines logo]()
$1,202
Best flights from Iowa to PanamaDiscover carefully curated flight deals from Iowa to Panama that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated November 12, 2026.
Discover carefully curated flight deals from Iowa to Panama that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated November 12, 2026.
This United Airlines deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/218:00 am -
1 stop8h 12m
Thu 2/48:55 am -
1 stop14h 35m
Deal found 11/11![United Airlines logo]()
$687
This American Airlines deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/216:14 pm -
2 stops18h 12m
Thu 2/44:55 pm -
2 stops18h 01m
Deal found 11/11![American Airlines logo]()
$692
This United Airlines deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/228:00 am -
1 stop10h 38m
Thu 1/2811:35 am -
1 stop11h 55m
Deal found 11/10![United Airlines logo]()
$721
This United Airlines deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/108:00 am -
1 stop10h 38m
Sat 3/203:41 pm -
2 stops20h 31m
Deal found 11/9![United Airlines logo]()
$795
This United Airlines deal was found by Cheapflights users on 11/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/88:00 am -
1 stop8h 12m
Tue 1/128:55 am -
1 stop14h 35m
Deal found 11/7![United Airlines logo]()
$820
Last-minute flights from Iowa to PanamaDiscover last-minute flight deals from Iowa to Panama. Data last updated November 12, 2026 and is based on user searches.
Discover last-minute flight deals from Iowa to Panama. Data last updated November 12, 2026 and is based on user searches.
This United Airlines deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/188:00 am -
1 stop10h 38m
Thu 11/268:55 am -
1 stop30h 25m
Deal found 11/8![United Airlines logo]()
$790
This American Airlines deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/205:01 am -
1 stop8h 33m
Sat 11/283:34 pm -
2 stops27h 53m
Deal found 11/11![American Airlines logo]()
$1,151
This United Airlines deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/256:45 pm -
2 stops24h 17m
Sun 12/68:55 am -
1 stop14h 26m
Deal found 11/10![United Airlines logo]()
$826
This United Airlines deal was found by Cheapflights users on 11/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/88:00 am -
1 stop8h 12m
Tue 1/128:55 am -
1 stop14h 35m
Deal found 11/7![United Airlines logo]()
$820
This American Airlines deal was found by Cheapflights users on 11/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/83:31 pm -
2 stops21h 42m
Tue 1/122:26 pm -
1 stop9h 33m
Deal found 11/7![American Airlines logo]()
$828
This United Airlines deal was found by Cheapflights users on 11/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/225:00 am -
2 stops11h 12m
Tue 12/2911:55 pm -
2 stops22h 28m
Deal found 11/7![United Airlines logo]()
$1,170
This United Airlines deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/235:00 am -
2 stops13h 38m
Wed 12/3011:35 am -
2 stops21h 20m
Deal found 11/8![United Airlines logo]()
$1,202
One-way flights from Iowa to PanamaSearch for one-way flight options from Iowa to Panama. Find affordable one-way fares based on user searches. Data last updated November 12, 2026.
Search for one-way flight options from Iowa to Panama. Find affordable one-way fares based on user searches. Data last updated November 12, 2026.
This United Airlines deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 1/106:30 pm -
2 stops24h 08m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/9![United Airlines logo]()
$316
This deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/88:00 am -
1 stop8h 12m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/8![United Airlines logo]()
$345
Find flight deals from Iowa to Panama
Keep the following information in mind while searching for Iowa to Panama flight deals. Data was last updated November 12, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $687 (United Airlines) |
One-way from | $316 (United Airlines) |
Popular in | June |
Cheapest in | February |
Average price | $717 |
Cheapflights Fare Finder
Customize your flight search to find flights from Iowa to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated November 12, 2026.
Use the filters below to find and compare flights from Iowa to Panama that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Des MoinesPanama City
DSM Des Moines - PTY Panama City Tocumen Intl
DSMPTY
Des Moines
Sun 1/10
8:00 am-2:45 pm
2 stops29h 45m
Panama City Tocumen Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$316
Quickest round-trip
Des MoinesPanama City
DSM Des Moines - PTY Panama City Tocumen Intl
DSMPTY
Des Moines
Fri 1/8
8:00 am-5:12 pm
1 stop8h 12m
Panama City Tocumen Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$345
Des MoinesPanama City
DSM Des Moines - PTY Panama City Tocumen Intl
DSMPTY
Des Moines
Thu 1/21
8:00 am-5:12 pm
1 stop8h 12m
Panama City Tocumen Intl
Thu 2/4
8:55 am-10:30 pm
1 stop14h 35m
$687
Des MoinesPanama City
DSM Des Moines - PTY Panama City Tocumen Intl
DSMPTY
Des Moines
Thu 1/21
6:14 pm-1:26 pm
2 stops18h 12m
Panama City Tocumen Intl
Thu 2/4
4:55 pm-9:56 am
2 stops18h 01m
$692
Des MoinesPanama City
DSM Des Moines - PTY Panama City Tocumen Intl
DSMPTY
Des Moines
Fri 1/22
8:00 am-7:38 pm
1 stop10h 38m
Panama City Tocumen Intl
Thu 1/28
11:35 am-10:30 pm
1 stop11h 55m
$721
Des MoinesPanama City
DSM Des Moines - PTY Panama City Tocumen Intl
DSMPTY
Des Moines
Wed 3/10
8:00 am-7:38 pm
1 stop10h 38m
Panama City Tocumen Intl
Sat 3/20
3:41 pm-12:12 pm
2 stops20h 31m
$795
Des MoinesPanama City
DSM Des Moines - PTY Panama City Tocumen Intl
DSMPTY
Des Moines
Tue 12/8
8:00 am-5:12 pm
1 stop8h 12m
Panama City Tocumen Intl
Tue 1/12
8:55 am-10:30 pm
1 stop14h 35m
$820
Sorted by cheapest first
Best time to book a flight from Iowa to Panama
Have a flexible travel schedule? Discover the best time to fly to Panama from Iowa with our price prediction graph.
DSM-PTY
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Iowa to Panama
USIA-PA0
DSM-PTY
No data available for this route at this time. Please check back soon.
Related info for your journey
Find useful and relevant information for your journey from Iowa to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Iowa to Panama
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Panama by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Iowa to Panama by cabin class
Find flights from Iowa to Panama, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Iowa and Panama flights
Browse other Iowa and Panama flight options. Last updated on November 12, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Iowa to Panama flights
Consider these flights traveling from Iowa to Panama.
Top airline flying from Iowa to Panama
Discover the top airline that operate flights from Iowa to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated November 12, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$461 | Average$613 | FlexibilityNo cancel fee | On-time69% |