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$114+ Cheap flights from Illinois to Panama

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/18. Fares are subject to change and may not be available on all flights or dates of travel.
ORD — PTY
Mar 5 — Mar 121
Thu 3/5
Thu 3/12
1 adult, Economy
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Cheap flight deals from Illinois to Panama

Cheapest flights from Illinois to Panama
Explore the most affordable flight options available from Illinois to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 3, 2026.

This Avianca deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/2610:20 pm
ORD
-
PTY
1 stop9h 30m
Avianca
Mon 3/29:45 am
PTY
-
ORD
1 stop11h 35m
Avianca
Deal found 2/2$357
This oojo deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/610:20 pm
ORD
-
PTY
1 stop14h 40m
Avianca
Sun 3/152:55 pm
PTY
-
ORD
1 stop30h 25m
Avianca
Deal found 2/3$382
This Mytrip deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/16:51 pm
ORD
-
PTY
2 stops28h 49m
Multiple Airlines
Fri 3/62:55 am
PTY
-
ORD
1 stop18h 25m
Multiple Airlines
Deal found 2/2$387
This Avianca deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/2311:20 pm
ORD
-
PTY
1 stop9h 30m
Avianca
Tue 3/242:55 pm
PTY
-
ORD
1 stop30h 25m
Avianca
Deal found 2/2$405
This Mytrip deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/410:20 pm
ORD
-
PTY
1 stop9h 30m
Multiple Airlines
Wed 3/119:45 am
PTY
-
ORD
2 stops22h 40m
Multiple Airlines
Deal found 2/2$407
This Mytrip deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/811:20 pm
ORD
-
PTY
1 stop9h 30m
Multiple Airlines
Wed 3/112:55 am
PTY
-
ORD
2 stops15h 36m
Multiple Airlines
Deal found 2/2$409
This Kiwi.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/199:18 am
ORD
-
PTY
2 stops14h 42m
Multiple Airlines
Tue 2/249:45 am
PTY
-
ORD
1 stop11h 35m
Multiple Airlines
Deal found 2/2$412
This Kiwi.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/239:18 am
ORD
-
PTY
2 stops14h 22m
Multiple Airlines
Thu 2/269:45 am
PTY
-
ORD
1 stop11h 35m
Multiple Airlines
Deal found 2/2$413
This United Airlines deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/46:00 am
STL
-
PTY
1 stop10h 07m
United Airlines
Wed 3/113:41 pm
PTY
-
STL
1 stop17h 40m
United Airlines
Deal found 2/3$415
This Kiwi.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/258:30 am
ORD
-
PTY
2 stops15h 10m
Multiple Airlines
Tue 3/32:55 am
PTY
-
ORD
1 stop18h 25m
Multiple Airlines
Deal found 2/2$419
This Mytrip deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/88:16 pm
ORD
-
PTY
3 stops28h 24m
Multiple Airlines
Wed 3/182:55 am
PTY
-
ORD
1 stop18h 25m
Multiple Airlines
Deal found 2/1$423
This United Airlines deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/216:30 am
STL
-
PTY
2 stops13h 01m
United Airlines
Sat 4/2510:55 pm
PTY
-
STL
2 stops13h 27m
United Airlines
Deal found 2/1$423

Find flight deals from Illinois to Panama

Keep the following information in mind while searching for Illinois to Panama flight deals. Data was last updated February 3, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$357
(Avianca)

One-way from

$114
(Avianca)

Popular in

May

Cheapest in

July

Average price

$572

Good round-trip deal

$355 or less

Good one-way deal

$180 or less
Provider with most accurate pricing for Chicago (CHI)-Panama City Tocumen Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Chicago (CHI)-Panama City Tocumen Intl flights.
Search Deals
From Illinois to Panama
Search Deals
One-way flight from Illinois to Panama
Search Deals
Highest demand for flights based on searches. 2% potential increase in price ($15 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($7 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in February 2026
Search Deals
Price to beat on a round-trip flight from Illinois to Panama.
Search Deals
Price to beat on a one-way flight from Illinois to Panama.
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Illinois to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 3, 2026.
Use the filters below to find and compare flights from Illinois to Panama that are best for you.

Fly from

Illinois

Fly to

Panama

Route

Depart

Return

Price

St. LouisPanama City

STL - PTY

STLPTY

Lambert-St Louis

Wed 3/11

6:00 am-6:38 pm

1 stop12h 38m

Panama City Tocumen Intl

Tue 3/24

3:41 pm-9:21 am

1 stop17h 40m

$415

St. LouisPanama City

STL - PTY

STLPTY

Lambert-St Louis

Wed 3/4

6:00 am-1:50 pm

1 stop6h 50m

Panama City Tocumen Intl

Wed 3/11

2:28 pm-11:58 pm

1 stop9h 30m

$415

St. LouisPanama City

STL - PTY

STLPTY

Lambert-St Louis

Wed 4/29

6:00 am-1:02 pm

1 stop7h 02m

Panama City Tocumen Intl

Wed 5/6

2:27 pm-11:34 pm

1 stop9h 07m

$415

St. LouisPanama City

STL - PTY

STLPTY

Lambert-St Louis

Wed 3/4

6:00 am-5:07 pm

1 stop10h 07m

Panama City Tocumen Intl

Wed 3/11

3:41 pm-9:21 am

1 stop17h 40m

$415

St. LouisPanama City

STL - PTY

STLPTY

Lambert-St Louis

Wed 4/29

6:00 am-2:14 pm

1 stop8h 14m

Panama City Tocumen Intl

Wed 5/6

3:30 pm-8:18 am

2 stops16h 48m

$419

St. LouisPanama City

STL - PTY

STLPTY

Lambert-St Louis

Tue 4/21

6:30 am-7:31 pm

2 stops13h 01m

Panama City Tocumen Intl

Sat 4/25

7:55 am-10:28 pm

1 stop14h 33m

$423

St. LouisPanama City

STL - PTY

STLPTY

Lambert-St Louis

Sun 3/29

6:00 am-2:14 pm

1 stop8h 14m

Panama City Tocumen Intl

Thu 4/2

3:30 pm-9:25 am

1 stop17h 55m

$432

St. LouisPanama City

STL - PTY

STLPTY

Lambert-St Louis

Sat 4/11

6:00 am-4:12 pm

1 stop10h 12m

Panama City Tocumen Intl

Tue 4/14

7:55 am-10:28 pm

1 stop14h 33m

$432

ChicagoPanama City

ORD - PTY

ORDPTY

Chicago O'Hare Intl

Tue 3/31

4:51 pm-2:15 pm

2 stops21h 24m

Panama City Tocumen Intl

Mon 4/13

5:55 pm-9:50 am

2 stops15h 55m

$471

ChicagoPanama City

ORD - PTY

ORDPTY

Chicago O'Hare Intl

Wed 2/25

7:23 pm-2:00 pm

2 stops17h 37m

Panama City Tocumen Intl

Wed 3/4

2:55 pm-9:39 am

2 stops19h 44m

$472

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/1

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Best time to book a flight from Illinois to Panama

Have a flexible travel schedule? Discover the best time to fly to Panama from Illinois with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Illinois to Panama

What is the cheapest month to book a flight from Illinois to Panama?

Currently, April is the cheapest month in which you can book a flight from Illinois to Panama (average of $264). Flying from Illinois to Panama in February is currently the most expensive (average of $503). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from IL to PA?

Find hourly flight availability from Illinois to Panama. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated February 3, 2026.

It’s optimal to fly from Illinois to Panama in the evening. By choosing this option you can save up to 14% on the cost of your flight, compared to a flight in the morning.

What is the cheapest day to fly from Illinois to Panama?

Use this chart to determine the cheapest time to fly round-trip from Illinois to Panama. Price data was last updated on January 31, 2026.

Travelers seeking maximum savings on their Illinois to Panama flight should consider departing on Monday evenings when fares are most often at their lowest. Wednesday at noon flights should be avoided if possible as fares are typically the most expensive at this time.

Weekly flight availability from Illinois to Panama

Explore weekly flight availability from Illinois to Panama. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated February 3, 2026.

The most flights from USIL to PA0 are scheduled on a Monday (5 on average). You will have fewer flight options on Wednesday, which is when the least amount of flights are scheduled (3 on average).

Related info for your journey

Find useful and relevant information for your journey from Illinois to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Illinois to Panama?

    For as low as $557, United Airlines can have you in Panama from Illinois in 5h 20m. There are 2330 mi between Illinois and Panama. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from Illinois to Panama one-way?

    The cheapest airlines for a one-way flight from Illinois to Panama are Avianca ($102), Copa Airlines ($225), and American Airlines ($449).

  • Can I find deals for flights from Illinois to Panama that include hotel bookings?

    Yes. In addition to deals on Illinois to Panama flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Illinois to Panama?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Illinois to Panama.

  • Can I find deals for business class flights from Illinois to Panama?

    Yes. Cheapflights offers flight deals from Illinois to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Illinois to Panama?

    Currently, April is the cheapest month in which you can book a flight from Illinois to Panama (average of $264). Flying from Illinois to Panama in February is currently the most expensive (average of $503). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Illinois to Panama

See prices for flight routes from nearby airports that may be better suited for you.
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Los Angeles to Liberia flights
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Miami to San José flights
George Bush Intcntl to San Pedro Sula flights
LaGuardia to Liberia flights
Dulles Intl to Guatemala City flights
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Top 5 airlines flying from Illinois to Panama

Discover the top 5 airlines that operate flights from Illinois to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 3, 2026.
AirlineCheapestAverageFlexibilityOn-time
AviancaCheapest$251Average$476FlexibilityNo cancel feeOn-time71%
Copa AirlinesCheapest$462Average$644FlexibilityNo cancel feeOn-time70%
DeltaCheapest$479Average$697FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$479Average$653FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$563Average$708FlexibilityNo cancel feeOn-time71%

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