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Panama City

$138+ Cheap flights from Santo Domingo (SDQ) to Panama City (PTY)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/30. Fares are subject to change and may not be available on all flights or dates of travel.
SDQ — PTY
May 6 — May 131
Tue 5/6
Tue 5/13
1 adult, Economy
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1. Tell us where you want to go

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Cheapflights Tip: The best prices from Santo Domingo Las Americas to Panama City Tocumen Intl are usually found in May or June, booked 27 days in advance, depart on a Wednesday or Thursday and return on a Thursday

Cheap flight deals from Santo Domingo to Panama City

Discover tips and strategies to find the most affordable flight options for your journey from Santo Domingo (SDQ) to Panama City (PTY). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated May 1, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$305
(Priceline)

One-way from

$138
(Avianca)

Popular in

March

Cheapest in

May

Average price

$370

Good round-trip deal

$264 or less

Good one-way deal

$174 or less
Provider with most accurate pricing for Santo Domingo Las Americas-Panama City Tocumen Intl flight deals.
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Provider most trusted by Cheapflights users for Santo Domingo Las Americas-Panama City Tocumen Intl flights.
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From Santo Domingo Las Americas to Panama City Tocumen Intl
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One-way flight from Santo Domingo Las Americas to Panama City Tocumen Intl
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Highest demand for flights based on searches. 9% potential increase in price ($43 potential increase over avg. RT price).
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Cheapest flight prices on average. 1% potential price decrease ($6 potential savings vs. average RT price).
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Average for round-trip flights in May 2025
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Price to beat on a round-trip flight from Santo Domingo Las Americas to Panama City Tocumen Intl.
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Price to beat on a one-way flight from Santo Domingo Las Americas to Panama City Tocumen Intl.
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Find flight deals from Santo Domingo to Panama City

Cheapest flights from Santo Domingo to Panama City
Explore the most affordable flight options available from Santo Domingo to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 1, 2025.

This Priceline deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/286:10 pmSDQ - PTY
1 stop7h 00mAvianca
Fri 7/2510:05 pmPTY - SDQ
1 stop11h 45mAvianca
Deal found 4/30$305
This Copa Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/285:21 amSDQ - PTY
Nonstop2h 37mCopa Airlines
Wed 6/256:55 pmPTY - SDQ
Nonstop2h 32mCopa Airlines
Deal found 4/30$362
This Mytrip deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/296:10 amSDQ - PTY
2 stops16h 00mMultiple Airlines
Mon 6/210:05 pmPTY - SDQ
1 stop11h 45mMultiple Airlines
Deal found 4/30$397
This United Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/201:10 pmSDQ - PTY
2 stops26h 04mUnited Airlines
Sat 10/253:30 pmPTY - SDQ
3 stops33h 19mUnited Airlines
Deal found 4/30$1,490
This Delta deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/122:28 pmSDQ - PTY
2 stops23h 20mDelta
Fri 5/302:13 pmPTY - SDQ
2 stops27h 15mDelta
Deal found 4/30$6,338

Cheapflights Fare Finder

Customize your flight search to find flights from Santo Domingo to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 1, 2025.
Use the filters below to find and compare flights from Santo Domingo to Panama City that are best for you.

Fly from

Santo Domingo

Fly to

Panama City

Route

Depart

Return

Price

Santo DomingoPanama City

SDQ - PTY

SDQPTY

Santo Domingo Las Americas

Wed 5/28

6:10 pm-8:55 am

1 stop15h 45m

Panama City Tocumen Intl

Wed 6/4

5:25 pm-10:50 am

1 stop16h 25m

$305

Santo DomingoPanama City

SDQ - PTY

SDQPTY

Santo Domingo Las Americas

Wed 5/28

5:21 am-6:58 am

Nonstop2h 37m

Panama City Tocumen Intl

Wed 6/25

6:55 pm-10:27 pm

Nonstop2h 32m

$362

Santo DomingoPanama City

SDQ - PTY

SDQPTY

Santo Domingo Las Americas

Thu 5/29

6:10 am-9:10 pm

2 stops16h 00m

Panama City Tocumen Intl

Mon 6/2

10:05 pm-10:50 am

1 stop11h 45m

$397

Santo DomingoPanama City

SDQ - PTY

SDQPTY

Santo Domingo Las Americas

Mon 10/20

1:10 pm-2:14 pm

2 stops26h 04m

Panama City Tocumen Intl

Sat 10/25

3:30 pm-1:49 am

3 stops33h 19m

$1,490

Santo DomingoPanama City

SDQ - PTY

SDQPTY

Santo Domingo Las Americas

Mon 5/12

2:28 pm-12:48 pm

2 stops23h 20m

Panama City Tocumen Intl

Fri 5/30

2:13 pm-6:28 pm

2 stops27h 15m

$6,338

Santo DomingoPanama City

SDQ - PTY

SDQPTY

Santo Domingo Las Americas

Fri 5/30

6:10 pm-12:10 am

1 stop7h 00m

$138

Santo DomingoPanama City

SDQ - PTY

SDQPTY

Santo Domingo Las Americas

Thu 5/8

8:53 am-10:30 am

Nonstop2h 37m

$536

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/30

Compare providers for flights from Santo Domingo to Panama City

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Santo Domingo to Panama City in May.
ProviderPrice AccuracyTrust Score*
FlightHubPrice Accuracy3 starsTrust Score*2 stars
eDreamsPrice Accuracy3 starsTrust Score*3 stars
JetabroadPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Santo Domingo-Panama City flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Santo Domingo-Panama City flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Santo Domingo-Panama City flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Santo Domingo-Panama City flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Santo Domingo-Panama City flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Santo Domingo to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Santo Domingo with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Santo Domingo to Panama City

How far ahead should I book a flight from Santo Domingo to Panama City?

Use this chart to determine the optimal time to book a round-trip flight from Santo Domingo to Panama City. Price data was last updated on April 25, 2025.

The best time to book flights from Santo Domingo to Panama City is 27 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from Santo Domingo to Panama City?

Currently, October is the cheapest month in which you can book a flight from Santo Domingo to Panama City (average of $478). Flying from Santo Domingo to Panama City in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SDQ to PTY?

Find hourly flight availability from Santo Domingo to Panama City. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated May 1, 2025.

One of the essential ways to save on airfare from Santo Domingo to Panama City is to remain as flexible as possible. Flights that are at noon tend to be the most expensive. A flight in the afternoon could potentially save you up to 15% on airfare.

Rainfall in Panama City by month

Plan your trip to Panama City by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Panama City ranges from 0.4 - 13.4 inches per month. October is typically the wettest month, when rainfall can reach 13.4 in. February is typically the driest time to visit Panama City when rainfall is around 0.4 in.

Temperature in Panama City by month

Plan your trip to Panama City by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Panama City, use this chart to help with planning. For those seeking warmer temperatures, February is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 78.8 F).

Reviews of airlines servicing Panama City

Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated May 1, 2025.
Delta
8.0
Very good
7,934 reviews

Boarding

8.2

Overall

8.0

Entertainment

7.9

Crew

8.5

Comfort

7.9

Food

7.3

Reviews

1 / 20
2.0
Mediocre

Santiago,Apr 2024

ATL - JNB

Bad experience with the staff boarding the gate. I couldn’t board with my carry on, personal item and a funny bag. I had to put my passport inside my pockets and put the funny bag inside the personal item. Then after passing the staff pull out everything again.
Delta
8.0
Very good
7,934 reviews
Delta
8.0
Very good
7,934 reviews

Boarding

8.2

Overall

8.0

Entertainment

7.9

Crew

8.5

Comfort

7.9

Food

7.3

Reviews

1 / 20
2.0
Mediocre

Santiago,Apr 2024

ATL - JNB

Bad experience with the staff boarding the gate. I couldn’t board with my carry on, personal item and a funny bag. I had to put my passport inside my pockets and put the funny bag inside the personal item. Then after passing the staff pull out everything again.
Copa Airlines
7.5
Good
1,415 reviews
Delta
8.0
Very good
7,934 reviews

Boarding

8.2

Overall

8.0

Entertainment

7.9

Crew

8.5

Comfort

7.9

Food

7.3

Reviews

1 / 20
2.0
Mediocre

Santiago,Apr 2024

ATL - JNB

Bad experience with the staff boarding the gate. I couldn’t board with my carry on, personal item and a funny bag. I had to put my passport inside my pockets and put the funny bag inside the personal item. Then after passing the staff pull out everything again.
United Airlines
7.4
Good
8,696 reviews
Delta
8.0
Very good
7,934 reviews

Boarding

8.2

Overall

8.0

Entertainment

7.9

Crew

8.5

Comfort

7.9

Food

7.3

Reviews

1 / 20
2.0
Mediocre

Santiago,Apr 2024

ATL - JNB

Bad experience with the staff boarding the gate. I couldn’t board with my carry on, personal item and a funny bag. I had to put my passport inside my pockets and put the funny bag inside the personal item. Then after passing the staff pull out everything again.
Avianca
6.7
Okay
2,317 reviews
Delta
8.0
Very good
7,934 reviews

Boarding

8.2

Overall

8.0

Entertainment

7.9

Crew

8.5

Comfort

7.9

Food

7.3

Reviews

1 / 20
2.0
Mediocre

Santiago,Apr 2024

ATL - JNB

Bad experience with the staff boarding the gate. I couldn’t board with my carry on, personal item and a funny bag. I had to put my passport inside my pockets and put the funny bag inside the personal item. Then after passing the staff pull out everything again.

Related info for your journey

Find useful and relevant information for your journey from Santo Domingo to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airports do I use to fly from Santo Domingo to Panama City?

    If you wish to fly to Panama City from Santo Domingo, then you need to book flights from Santo Domingo Las Americas to Panama City Tocumen Intl. There are 2 flights from Las Americas (SDQ) to Tocumen Intl (PTY) per day to choose from. Flights to Panama City from Las Americas are available from 2 different airlines, which means you should have some options if you want to compare airfare deals. 2h 35m is how long a nonstop flight from Santo Domingo to Panama City Tocumen Intl typically takes.

  • How popular is this Santo Domingo to Panama City flight route?

    This flight path from Santo Domingo Las Americas to Panama City Tocumen Intl was viewed by 97 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • What are the cheapest airlines flying from Santo Domingo to Panama City round-trip?

    Cheapflights users have booked flights from Santo Domingo to Panama City round-trip from $305. Other airlines that can offer you cheap pricing are Copa Airlines, from $362, and United Airlines, from $1,490. Avianca is 30% cheaper than the average price of flights available within the next 90 days to this destination.

  • What are the most reliable airlines from Santo Domingo to Panama City?

    Consider KLM (98%), Air France (98%) or Turkish Airlines (98%) when booking your flight. These represent the most reliable airlines when flying from Santo Domingo to Panama City.

  • What are the cheapest flights from Santo Domingo to Panama City?

    Looking at all options, your cheapest flight can be booked for $134. While the most popular route (Santo Domingo Las Americas - Panama City Tocumen Intl) can be booked for $327 on average our data indicates $285 when flying from Santo Domingo to Panama City.

  • Can I find deals for flights from Santo Domingo to Panama City that include hotel bookings?

    Yes. In addition to deals on Santo Domingo to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Santo Domingo to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santo Domingo to Panama City.

  • Can I find deals for business class flights from Santo Domingo to Panama City?

    Yes. Cheapflights offers flight deals from Santo Domingo to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Santo Domingo to Panama City?

    Currently, October is the cheapest month in which you can book a flight from Santo Domingo to Panama City (average of $478). Flying from Santo Domingo to Panama City in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Santo Domingo to Panama City

See prices for flight routes from nearby airports that may be better suited for you.
Punta Cana to Panama City flights

Top 2 airlines flying from Santo Domingo to Panama City

Discover the top 2 airlines that operate flights from Santo Domingo to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 1, 2025.
AirlineCheapestAverageFlexibilityOn-time
AviancaCheapest$286Average$352FlexibilityNo cancel feeOn-time71%
Copa AirlinesCheapest$370Average$486FlexibilityNo cancel feeOn-time70%

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