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$248+ Cheap flights from Santiago (SCL) to Panama City (PTY)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/1. Fares are subject to change and may not be available on all flights or dates of travel.
SCL — PTY
Jun 17 — Jun 241
Tue 6/17
Tue 6/24
1 adult, Economy
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Cheapflights Tip: The best prices from Santiago Arturo Merino Benitez to Panama City Tocumen Intl are usually found in August or October, booked 60 days in advance, depart on a Sunday or Friday and return on a Thursday

Cheap flight deals from Santiago to Panama City

Discover tips and strategies to find the most affordable flight options for your journey from Santiago (SCL) to Panama City (PTY). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated June 12, 2025.

Round-trip from

$536
(Avianca)

One-way from

$248
(FlightHub)

Popular in

January

Cheapest in

August

Average price

$546

Good round-trip deal

$468 or less

Good one-way deal

$319 or less
From Santiago Arturo Merino Benitez to Panama City Tocumen Intl
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One-way flight from Santiago Arturo Merino Benitez to Panama City Tocumen Intl
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Highest demand for flights based on searches. 6% potential increase in price ($36 potential increase over avg. RT price).
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Cheapest flight prices on average. 1% potential price decrease ($7 potential savings vs. average RT price).
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Average for round-trip flights in June 2025
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Price to beat on a round-trip flight from Santiago Arturo Merino Benitez to Panama City Tocumen Intl.
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Price to beat on a one-way flight from Santiago Arturo Merino Benitez to Panama City Tocumen Intl.
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Find flight deals from Santiago to Panama City

Cheapest flights from Santiago to Panama City
Explore the most affordable flight options available from Santiago to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 12, 2025.

This Avianca deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/86:10 amSCL - PTY
1 stop11h 20mAvianca
Mon 9/293:25 amPTY - SCL
1 stop9h 00mAvianca
Deal found 6/12$536
This Copa Airlines deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/1011:27 amSCL - PTY
Nonstop6h 53mCopa Airlines
Sun 8/177:11 pmPTY - SCL
Nonstop6h 36mCopa Airlines
Deal found 6/12$540
This Mytrip deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/256:10 amSCL - PTY
1 stop11h 20mMultiple Airlines
Thu 7/313:20 amPTY - SCL
3 stops23h 57mMultiple Airlines
Deal found 6/10$662
This United Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/1410:45 pmSCL - PTY
2 stops46h 04mUnited Airlines
Mon 11/243:35 pmPTY - SCL
2 stops39h 15mUnited Airlines
Deal found 6/11$1,114

Cheapflights Fare Finder

Customize your flight search to find flights from Santiago to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 12, 2025.
Use the filters below to find and compare flights from Santiago to Panama City that are best for you.

Fly from

Santiago

Fly to

Panama City

Route

Depart

Return

Price

SantiagoPanama City

SCL - PTY

SCLPTY

Santiago Arturo Merino Benitez

Fri 8/8

6:10 am-4:30 pm

1 stop11h 20m

Panama City Tocumen Intl

Mon 9/29

3:25 am-2:25 pm

1 stop9h 00m

$536

SantiagoPanama City

SCL - PTY

SCLPTY

Santiago Arturo Merino Benitez

Sun 8/10

2:23 am-8:16 am

Nonstop6h 53m

Panama City Tocumen Intl

Sun 8/24

11:48 am-7:24 pm

Nonstop6h 36m

$540

SantiagoPanama City

SCL - PTY

SCLPTY

Santiago Arturo Merino Benitez

Fri 7/25

6:10 am-4:30 pm

1 stop11h 20m

Panama City Tocumen Intl

Thu 7/31

3:20 am-4:17 am

3 stops23h 57m

$662

SantiagoPanama City

SCL - PTY

SCLPTY

Santiago Arturo Merino Benitez

Fri 11/14

10:45 pm-6:49 pm

2 stops46h 04m

Panama City Tocumen Intl

Mon 11/24

3:35 pm-8:50 am

2 stops39h 15m

$1,114

SantiagoPanama City

SCL - PTY

SCLPTY

Santiago Arturo Merino Benitez

Fri 8/1

6:10 am-9:10 pm

1 stop16h 00m

$248

SantiagoPanama City

SCL - PTY

SCLPTY

Santiago Arturo Merino Benitez

Sat 7/12

8:15 pm-9:10 pm

3 stops25h 55m

$348

SantiagoPanama City

SCL - PTY

SCLPTY

Santiago Arturo Merino Benitez

Sun 8/10

2:23 am-8:16 am

Nonstop6h 53m

$614

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/10

Best time to book a flight from Santiago to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Santiago with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Santiago to Panama City

What is the cheapest month to book a flight from Santiago to Panama City?

Currently, October is the cheapest month in which you can book a flight from Santiago to Panama City (average of $478). Flying from Santiago to Panama City in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SCL to PTY?

Find hourly flight availability from Santiago to Panama City. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated June 12, 2025.

It’s typically best to fly out from Santiago to Panama City in the afternoon. Doing so could potentially save you 31% on the flight price compared to flying at noon, which is usually more expensive.

Weekly flight availability from Santiago to Panama City

Explore weekly flight availability from Santiago to Panama City. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated June 12, 2025.

The most flights from SCL to PTY are scheduled on a Monday (7 on average). You will have fewer flight options on Monday, which is when the least amount of flights are scheduled (7 on average).

Rainfall in Panama City by month

Plan your trip to Panama City by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Panama City ranges from 0.4 - 13.4 inches per month. October is typically the wettest month, when rainfall can reach 13.4 in. February is typically the driest time to visit Panama City when rainfall is around 0.4 in.

Temperature in Panama City by month

Plan your trip to Panama City by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Panama City, use this chart to help with planning. For those seeking warmer temperatures, February is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 78.8 F).

Reviews of airlines servicing Panama City

Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated June 12, 2025.
Copa Airlines
7.5
Good
1,451 reviews

Boarding

7.8

Comfort

7.4

Food

6.8

Overall

7.5

Entertainment

6.8

Crew

8.1

Reviews

1 / 20
6.0
Good

Paul,May 2025

PTY - AUA

Had to use my phone for entertainment? Once we landed people were already out their seats and standing in the isles while the plane was still taxiing to the gate. This is unsafe and flight crew had a responsibility to ensure that people remain seated until the pilots turn off the seatbelt sign.
Copa Airlines
7.5
Good
1,451 reviews
Copa Airlines
7.5
Good
1,451 reviews

Boarding

7.8

Comfort

7.4

Food

6.8

Overall

7.5

Entertainment

6.8

Crew

8.1

Reviews

1 / 20
6.0
Good

Paul,May 2025

PTY - AUA

Had to use my phone for entertainment? Once we landed people were already out their seats and standing in the isles while the plane was still taxiing to the gate. This is unsafe and flight crew had a responsibility to ensure that people remain seated until the pilots turn off the seatbelt sign.
United Airlines
7.4
Good
8,790 reviews
Copa Airlines
7.5
Good
1,451 reviews

Boarding

7.8

Comfort

7.4

Food

6.8

Overall

7.5

Entertainment

6.8

Crew

8.1

Reviews

1 / 20
6.0
Good

Paul,May 2025

PTY - AUA

Had to use my phone for entertainment? Once we landed people were already out their seats and standing in the isles while the plane was still taxiing to the gate. This is unsafe and flight crew had a responsibility to ensure that people remain seated until the pilots turn off the seatbelt sign.
Avianca
6.7
Okay
2,345 reviews
Copa Airlines
7.5
Good
1,451 reviews

Boarding

7.8

Comfort

7.4

Food

6.8

Overall

7.5

Entertainment

6.8

Crew

8.1

Reviews

1 / 20
6.0
Good

Paul,May 2025

PTY - AUA

Had to use my phone for entertainment? Once we landed people were already out their seats and standing in the isles while the plane was still taxiing to the gate. This is unsafe and flight crew had a responsibility to ensure that people remain seated until the pilots turn off the seatbelt sign.

Related info for your journey

Find useful and relevant information for your journey from Santiago to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airports do I use to fly from Santiago to Panama City?

    If you book a flight from Santiago to Panama City, you will be flying from Arturo Merino Benitez to Tocumen Intl. Flights to Panama City Tocumen Intl (PTY) from Santiago Arturo Merino Benitez (SCL) take 6h 52m for a nonstop flight. There are 7 flights from Arturo Merino Benitez to Panama City per day from 2 airlines.

  • How popular is this Santiago to Panama City flight route?

    This flight path from Santiago Arturo Merino Benitez to Panama City Tocumen Intl was viewed by 11 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • What are the cheapest airlines flying from Santiago to Panama City round-trip?

    According to our current data, Avianca ($536), Copa Airlines ($540), and United Airlines ($1,114) offers the cheapest pricing from Santiago to Panama City.

  • What are the most reliable airlines from Santiago to Panama City?

    Consider KLM (98%), Turkish Airlines (97%) or Copa Airlines (95%) when booking your flight. These represent the most reliable airlines when flying from Santiago to Panama City.

  • What are the cheapest flights from Santiago to Panama City?

    On average you can expect to pay $873 for a flight from Santiago to Panama City. The cheapest flight overall is $194 while the most popular route, (Santiago Arturo Merino Benitez - Panama City Tocumen Intl) is currently priced at $540.

  • Can I find deals for flights from Santiago to Panama City that include hotel bookings?

    Yes. In addition to deals on Santiago to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Santiago to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santiago to Panama City.

  • Can I find deals for business class flights from Santiago to Panama City?

    Yes. Cheapflights offers flight deals from Santiago to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Santiago to Panama City?

    Currently, October is the cheapest month in which you can book a flight from Santiago to Panama City (average of $478). Flying from Santiago to Panama City in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Top 2 airlines flying from Santiago to Panama City

Discover the top 2 airlines that operate flights from Santiago to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 12, 2025.
AirlineCheapestAverageFlexibilityOn-time
AviancaCheapest$302Average$464FlexibilityNo cancel feeOn-time71%
Copa AirlinesCheapest$424Average$591FlexibilityNo cancel feeOn-time70%

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