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Panama City

$232+ Cheap flights from Santiago (SCL) to Panama City (PTY)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/24. Fares are subject to change and may not be available on all flights or dates of travel.
SCL — PTY
apr. 7 — apr. 141
ti. 4/7
ti. 4/14
1 adult, Economy
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Cheapflights Tip: The best prices from Santiago Arturo Merino Benitez to Panama City Tocumen Intl are usually found in November or March, booked 86 days in advance, depart on a Wednesday or Friday and return on a Monday

Cheap flight deals from Santiago to Panama City

Cheapest flights from Santiago to Panama City
Explore the most affordable flight options available from Santiago to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on mars 8, 2026.

This Avianca deal was found by Cheapflights users on 3/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
fr. 3/204:25 pm
SCL
-
PTY
1 stop10h 15m
Avianca
ti. 3/249:45 am
PTY
-
SCL
1 stop12h 45m
Avianca
Deal found 3/4$503
This Avianca deal was found by Cheapflights users on 3/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sø. 5/36:40 am
SCL
-
PTY
1 stop11h 20m
Avianca
sø. 5/103:10 pm
PTY
-
SCL
1 stop12h 35m
Avianca
Deal found 3/4$506
This Avianca deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sø. 4/196:40 am
SCL
-
PTY
1 stop11h 20m
Avianca
lø. 4/253:05 am
PTY
-
SCL
1 stop10h 10m
Avianca
Deal found 3/5$507
This Trip.com deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sø. 4/196:40 am
SCL
-
PTY
1 stop8h 35m
Avianca
to. 4/3010:10 am
PTY
-
SCL
1 stop12h 10m
Avianca
Deal found 3/7$523
This Copa Airlines deal was found by Cheapflights users on 3/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
fr. 3/205:44 am
SCL
-
PTY
Nonstop6h 51m
Copa Airlines
sø. 4/57:25 pm
PTY
-
SCL
Nonstop6h 35m
Copa Airlines
Deal found 3/4$527
This Avianca deal was found by Cheapflights users on 3/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
fr. 3/64:25 pm
SCL
-
PTY
1 stop10h 15m
Avianca
sø. 3/222:55 am
PTY
-
SCL
1 stop10h 25m
Avianca
Deal found 3/4$533
This FlightHub deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lø. 5/3012:30 am
SCL
-
PTY
1 stop14h 45m
Avianca
on. 6/33:05 am
PTY
-
SCL
1 stop10h 10m
Avianca
Deal found 3/6$541
This Copa Airlines deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
on. 4/13:30 am
SCL
-
PTY
Nonstop6h 46m
Copa Airlines
sø. 4/59:35 pm
PTY
-
SCL
Nonstop6h 35m
Copa Airlines
Deal found 3/5$557
This Copa Airlines deal was found by Cheapflights users on 3/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ti. 6/212:01 am
SCL
-
PTY
Nonstop6h 54m
Copa Airlines
ma. 6/223:51 pm
PTY
-
SCL
Nonstop6h 35m
Copa Airlines
Deal found 3/4$558
This Avianca deal was found by Cheapflights users on 3/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
fr. 7/312:30 am
SCL
-
PTY
1 stop14h 45m
Avianca
lø. 7/183:05 am
PTY
-
SCL
1 stop10h 10m
Avianca
Deal found 3/4$560

Find flight deals from Santiago to Panama City

Discover tips and strategies to find the most affordable flight options for your journey from Santiago (SCL) to Panama City (PTY). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated mars 8, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$503
(Avianca)

One-way from

$232
(Super.com)

Popular in

September

Cheapest in

November

Average price

$540

Good round-trip deal

$539 or less

Good one-way deal

$283 or less
Provider with most accurate pricing for Santiago Arturo Merino Benitez-Panama City Tocumen Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Santiago Arturo Merino Benitez-Panama City Tocumen Intl flights.
Search Deals
From Santiago Arturo Merino Benitez to Panama City Tocumen Intl
Search Deals
One-way flight from Santiago Arturo Merino Benitez to Panama City Tocumen Intl
Search Deals
Highest demand for flights based on searches. 4% potential increase in price ($26 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($9 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in March 2026
Search Deals
Price to beat on a round-trip flight from Santiago Arturo Merino Benitez to Panama City Tocumen Intl.
Search Deals
Price to beat on a one-way flight from Santiago Arturo Merino Benitez to Panama City Tocumen Intl.
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Santiago to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated mars 8, 2026.
Use the filters below to find and compare flights from Santiago to Panama City that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

SantiagoPanama City

SCL - PTY

SCLPTY

Santiago Arturo Merino Benitez

on. 5/20

11:17 am-5:11 pm

Nonstop6h 54m

Panama City Tocumen Intl

sø. 5/31

7:25 pm-3:00 am

Nonstop6h 35m

$527

SantiagoPanama City

SCL - PTY

SCLPTY

Santiago Arturo Merino Benitez

fr. 5/1

11:17 am-5:11 pm

Nonstop6h 54m

Panama City Tocumen Intl

on. 5/13

7:25 pm-3:00 am

Nonstop6h 35m

$527
Quickest round-trip

SantiagoPanama City

SCL - PTY

SCLPTY

Santiago Arturo Merino Benitez

ma. 4/13

2:30 am-8:16 am

Nonstop6h 46m

Panama City Tocumen Intl

ti. 4/21

3:51 pm-11:26 pm

Nonstop6h 35m

$527

SantiagoPanama City

SCL - PTY

SCLPTY

Santiago Arturo Merino Benitez

ma. 4/27

11:25 am-5:11 pm

Nonstop6h 46m

Panama City Tocumen Intl

ma. 5/4

3:51 pm-11:26 pm

Nonstop6h 35m

$527

SantiagoPanama City

SCL - PTY

SCLPTY

Santiago Arturo Merino Benitez

fr. 4/17

11:25 am-5:11 pm

Nonstop6h 46m

Panama City Tocumen Intl

on. 4/22

11:48 am-7:23 pm

Nonstop6h 35m

$527
Cheapest one-way

SantiagoPanama City

SCL - PTY

SCLPTY

Santiago Arturo Merino Benitez

sø. 4/26

7:55 pm-2:55 pm

2 stops44h 00m

$291

SantiagoPanama City

SCL - PTY

SCLPTY

Santiago Arturo Merino Benitez

fr. 4/24

3:16 pm-2:15 pm

2 stops23h 59m

$331

SantiagoPanama City

SCL - PTY

SCLPTY

Santiago Arturo Merino Benitez

ti. 8/4

12:30 am-9:15 am

1 stop9h 45m

$661

SantiagoPanama City

SCL - PTY

SCLPTY

Santiago Arturo Merino Benitez

on. 4/15

11:25 am-5:11 pm

Nonstop6h 46m

$896

SantiagoPanama City

SCL - PTY

SCLPTY

Santiago Arturo Merino Benitez

sø. 4/26

11:25 am-5:11 pm

Nonstop6h 46m

$896

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/4

Showing 1-10 of 16 resultsSorted by cheapest first
1
2
  • Most accurate provider: When it comes to deals on Santiago-Panama City flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Santiago-Panama City flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Santiago-Panama City flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Santiago-Panama City flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Santiago-Panama City flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Santiago to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Santiago with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Santiago to Panama City

How far ahead should I book a flight from Santiago to Panama City?

Use this chart to determine the optimal time to book a round-trip flight from Santiago to Panama City. Price data was last updated on March 6, 2026.

The best time to book flights from Santiago to Panama City is 86 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from Santiago to Panama City?

Currently, January is the cheapest month in which you can book a flight from Santiago to Panama City (average of $270). Flying from Santiago to Panama City in June is currently the most expensive (average of $487). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SCL to PTY?

Find hourly flight availability from Santiago to Panama City. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated mars 8, 2026.

When flying from Santiago to Panama City, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Reviews of airlines servicing Panama City

Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated mars 8, 2026.
Read through reviews of airlines operating flights from Santiago to Panama City, such as Copa Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Copa Airlines
7.5
Good
1,565 reviews

Food

6.8

Entertainment

6.8

Crew

8.1

Comfort

7.4

Boarding

7.8

Overall

7.5

Reviews

1 / 20
2.0
Mediocre

Katerine,Mar 2026

LAX - PTY

Really i was expecting be more friendly with family’s, more when you travel with a infant. We expected like a priority to boarding or be friendly with the spots on the aeroplane.
Copa Airlines
7.5
Good
1,565 reviews
Copa Airlines
7.5
Good
1,565 reviews

Food

6.8

Entertainment

6.8

Crew

8.1

Comfort

7.4

Boarding

7.8

Overall

7.5

Reviews

1 / 20
2.0
Mediocre

Katerine,Mar 2026

LAX - PTY

Really i was expecting be more friendly with family’s, more when you travel with a infant. We expected like a priority to boarding or be friendly with the spots on the aeroplane.

Related info for your journey

Find useful and relevant information for your journey from Santiago to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airports do I use to fly from Santiago to Panama City?

    If you book a flight from Santiago to Panama City, you will be flying from Arturo Merino Benitez to Tocumen Intl. Flights to Panama City Tocumen Intl (PTY) from Santiago Arturo Merino Benitez (SCL) take 6h 43m for a nonstop flight. There are 6 flights from Arturo Merino Benitez to Panama City per day from 1 airline.

  • How popular is this Santiago to Panama City flight route?

    This flight path from Santiago Arturo Merino Benitez to Panama City Tocumen Intl was viewed by 12 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • How long is the flight from Santiago to Panama City?

    Airlines like Avianca and Copa Airlines fly from Santiago to Panama City in about 6h 51m. The time it takes to get you to your destination can typically vary by up to 3h 24m. The distance between Santiago and Panama City is about 2986 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What is the cheapest airline to fly from Santiago to Panama City round-trip?

    According to our current data, Copa Airlines ($450), offers the cheapest pricing from Santiago to Panama City. Copa Airlines is 18% cheaper than the average price of flights available within the next 90 days to this destination.

  • What are the cheapest flights from Santiago to Panama City?

    On average you can expect to pay $855 for a flight from Santiago to Panama City. The cheapest flight overall is $194 while the most popular route, (Santiago Arturo Merino Benitez - Panama City Tocumen Intl) is currently priced at $511.

  • Can I find deals for flights from Santiago to Panama City that include hotel bookings?

    Yes. In addition to deals on Santiago to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Santiago to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santiago to Panama City.

  • Can I find deals for business class flights from Santiago to Panama City?

    Yes. Cheapflights offers flight deals from Santiago to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Santiago to Panama City?

    Currently, January is the cheapest month in which you can book a flight from Santiago to Panama City (average of $270). Flying from Santiago to Panama City in June is currently the most expensive (average of $487). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Top airline flying from Santiago to Panama City

Discover the top airline that operate flights from Santiago to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated mars 8, 2026.
AirlineCheapestAverageFlexibilityOn-time
Copa AirlinesCheapest$450Average$598FlexibilityNo cancel feeOn-time70%

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