$399+ Cheap flights from Harrisburg (MDT) to Panama City (PTY)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/24. Fares are subject to change and may not be available on all flights or dates of travel.
MDT — PTY
Oct 31 — Nov 71
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from Harrisburg to Panama City with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Harrisburg to Panama City
Cheapest
Best
Last-minute
One-way
Cheapest flights from Harrisburg to Panama CityExplore the most affordable flight options available from Harrisburg to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 1, 2026.
Explore the most affordable flight options available from Harrisburg to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 1, 2026.
This American Airlines deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/137:06 pm -
2 stops18h 56m
Thu 10/222:02 pm -
2 stops22h 16m
Deal found 9/27![American Airlines logo]()
$721
This American Airlines deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/238:09 pm -
2 stops17h 53m
Fri 10/302:02 pm -
2 stops20h 15m
Deal found 9/28![American Airlines logo]()
$755
This Ovago deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ovago is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/122:00 pm -
2 stops24h 45m
Mon 1/184:41 pm -
2 stops20h 49m
Deal found 9/30![Copa Airlines logo]()
$896
This United Airlines deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/128:13 pm -
2 stops23h 49m
Thu 11/194:41 pm -
2 stops17h 12m
Deal found 9/28![United Airlines logo]()
$1,015
This KAYAK deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/266:20 am -
2 stops22h 50m
Thu 12/3111:35 am -
2 stops22h 15m
Deal found 9/29![Copa Airlines logo]()
$1,415
This American Airlines deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/217:18 pm -
2 stops20h 15m
Sun 1/34:33 pm -
2 stops22h 09m
Deal found 9/29![American Airlines logo]()
$1,454
This Kiwi.com deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/239:13 am -
1 stop23h 26m
Fri 10/3012:56 pm -
2 stops50h 22m
Deal found 9/28![Multiple Airlines logo]()
$1,546
This BusinessClass deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure BusinessClass is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/267:18 pm -
2 stops20h 15m
Fri 1/12:41 pm -
2 stops29h 55m
Deal found 9/27![GOL logo]()
$1,607
This Kiwi.com deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/219:40 am -
1 stop22h 38m
Sun 1/312:03 pm -
2 stops29h 26m
Deal found 9/29![Multiple Airlines logo]()
$1,711
This Delta deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/236:00 am -
1 stop7h 59m
Fri 10/302:24 pm -
1 stop8h 15m
Deal found 9/28![Delta logo]()
$1,763
This Delta deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/126:00 am -
1 stop8h 03m
Mon 1/183:20 pm -
1 stop8h 18m
Deal found 9/30![Delta logo]()
$2,652
Best flights from Harrisburg to Panama CityDiscover carefully curated flight deals from Harrisburg to Panama City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 1, 2026.
Discover carefully curated flight deals from Harrisburg to Panama City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 1, 2026.
This United Airlines deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/186:30 am -
2 stops13h 08m
Wed 1/278:55 am -
2 stops25h 00m
Deal found 9/28![United Airlines logo]()
$681
This Ovago deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ovago is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/122:00 pm -
2 stops24h 45m
Mon 1/184:41 pm -
2 stops20h 49m
Deal found 9/30![Copa Airlines logo]()
$896
This BusinessClass deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure BusinessClass is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/267:18 pm -
2 stops20h 15m
Fri 1/12:41 pm -
2 stops29h 55m
Deal found 9/27![GOL logo]()
$1,607
This Delta deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/236:00 am -
1 stop7h 59m
Fri 10/302:24 pm -
1 stop8h 15m
Deal found 9/28![Delta logo]()
$1,763
This United Airlines deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/128:13 pm -
2 stops23h 49m
Thu 11/194:41 pm -
2 stops17h 12m
Deal found 9/28![United Airlines logo]()
$1,015
This Delta deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/186:00 am -
1 stop7h 55m
Wed 1/273:20 pm -
1 stop8h 18m
Deal found 9/28![Delta logo]()
$2,050
This Delta deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/126:00 am -
1 stop8h 03m
Mon 1/183:20 pm -
1 stop8h 18m
Deal found 9/30![Delta logo]()
$2,652
This Gurufare deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gurufare is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/136:30 am -
1 stop15h 01m
Thu 10/229:45 am -
2 stops12h 44m
Deal found 9/27![Copa Airlines logo]()
$3,063
This Delta deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/2612:27 pm -
1 stop9h 18m
Thu 12/318:00 am -
1 stop13h 28m
Deal found 9/29![Delta logo]()
$2,903
Last-minute flights from Harrisburg to Panama CityDiscover last-minute flight deals from Harrisburg to Panama City. Data last updated October 1, 2026 and is based on user searches.
Discover last-minute flight deals from Harrisburg to Panama City. Data last updated October 1, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/137:06 pm -
2 stops18h 56m
Thu 10/222:02 pm -
2 stops22h 16m
Deal found 9/27![American Airlines logo]()
$721
This Gurufare deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gurufare is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/136:30 am -
1 stop15h 01m
Thu 10/229:45 am -
2 stops12h 44m
Deal found 9/27![Copa Airlines logo]()
$3,063
This American Airlines deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/238:09 pm -
2 stops17h 53m
Fri 10/302:02 pm -
2 stops20h 15m
Deal found 9/28![American Airlines logo]()
$755
This Kiwi.com deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/239:13 am -
1 stop23h 26m
Fri 10/3012:56 pm -
2 stops50h 22m
Deal found 9/28![Multiple Airlines logo]()
$1,546
This Delta deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/236:00 am -
1 stop7h 59m
Fri 10/302:24 pm -
1 stop8h 15m
Deal found 9/28![Delta logo]()
$1,763
One-way flights from Harrisburg to Panama CitySearch for one-way flight options from Harrisburg to Panama City. Find affordable one-way fares based on user searches. Data last updated October 1, 2026.
Search for one-way flight options from Harrisburg to Panama City. Find affordable one-way fares based on user searches. Data last updated October 1, 2026.
This Avianca deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/242:55 pm -
2 stops12h 00m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/28![Avianca logo]()
$399
This Kiwi.com deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/2411:53 am -
3 stops33h 38m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/28![Multiple Airlines logo]()
$515
This Mytrip deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/266:20 am -
2 stops19h 50m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/27![Avianca logo]()
$610
This American Airlines deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/267:18 pm -
2 stops20h 15m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/27![American Airlines logo]()
$678
This Kiwi.com deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/264:23 pm -
3 stops39h 44m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/27![Multiple Airlines logo]()
$704
This Delta deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/2612:27 pm -
1 stop9h 18m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/27![Delta logo]()
$1,557
This KAYAK deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/266:20 am -
1 stop14h 15m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/27![Copa Airlines logo]()
$2,162
Find flight deals from Harrisburg to Panama City
Discover tips and strategies to find the most affordable flight options for your journey from Harrisburg (MDT) to Panama City (PTY). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 1, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $663 (American Airlines) |
One-way from | $399 (Avianca) |
Cheapflights Fare Finder
Customize your flight search to find flights from Harrisburg to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 1, 2026.
Use the filters below to find and compare flights from Harrisburg to Panama City that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
HarrisburgPanama City
MDT Harrisburg - PTY Panama City Tocumen Intl
MDTPTY
Harrisburg
Sat 10/24
2:55 pm-1:55 am
2 stops12h 00m
Panama City Tocumen Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$399
HarrisburgPanama City
MDT Harrisburg - PTY Panama City Tocumen Intl
MDTPTY
Harrisburg
Sat 12/26
7:18 pm-3:33 pm
2 stops20h 15m
Panama City Tocumen Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$678
HarrisburgPanama City
MDT Harrisburg - PTY Panama City Tocumen Intl
MDTPTY
Harrisburg
Mon 1/18
6:30 am-7:38 pm
2 stops13h 08m
Panama City Tocumen Intl
Wed 1/27
8:55 am-9:55 am
2 stops25h 00m
$681
HarrisburgPanama City
MDT Harrisburg - PTY Panama City Tocumen Intl
MDTPTY
Harrisburg
Sat 12/26
4:23 pm-8:07 am
3 stops39h 44m
Panama City Tocumen Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$704
HarrisburgPanama City
MDT Harrisburg - PTY Panama City Tocumen Intl
MDTPTY
Harrisburg
Sat 10/24
11:53 am-7:39 am
1 stop20h 46m
Panama City Tocumen Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$781
HarrisburgPanama City
MDT Harrisburg - PTY Panama City Tocumen Intl
MDTPTY
Harrisburg
Sat 12/12
2:00 pm-2:45 pm
2 stops24h 45m
Panama City Tocumen Intl
Mon 1/18
4:41 pm-1:30 pm
2 stops20h 49m
$896
HarrisburgPanama City
MDT Harrisburg - PTY Panama City Tocumen Intl
MDTPTY
Harrisburg
Thu 11/12
8:13 pm-8:02 pm
2 stops23h 49m
Panama City Tocumen Intl
Thu 11/19
4:41 pm-9:53 am
2 stops17h 12m
$1,015
Quickest round-trip
HarrisburgPanama City
MDT Harrisburg - PTY Panama City Tocumen Intl
MDTPTY
Harrisburg
Sat 12/26
12:27 pm-9:45 pm
1 stop9h 18m
Panama City Tocumen Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$1,557
HarrisburgPanama City
MDT Harrisburg - PTY Panama City Tocumen Intl
MDTPTY
Harrisburg
Sat 12/26
7:18 pm-3:33 pm
2 stops20h 15m
Panama City Tocumen Intl
Fri 1/1
2:41 pm-8:36 pm
2 stops29h 55m
$1,607
HarrisburgPanama City
MDT Harrisburg - PTY Panama City Tocumen Intl
MDTPTY
Harrisburg
Fri 10/23
6:00 am-12:59 pm
1 stop7h 59m
Panama City Tocumen Intl
Fri 10/30
2:24 pm-11:39 pm
1 stop8h 15m
$1,763
Showing 1-10 of 14 resultsSorted by cheapest first
Compare providers for flights from Harrisburg to Panama City
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Harrisburg to Panama City in October.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Harrisburg-Panama City flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Harrisburg-Panama City flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Harrisburg-Panama City flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Harrisburg-Panama City flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Harrisburg-Panama City flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Harrisburg to Panama City
Have a flexible travel schedule? Discover the best time to fly to Panama City from Harrisburg with our price prediction graph.
MDT-PTY
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Related info for your journey
Find useful and relevant information for your journey from Harrisburg to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
Other flight options
Panama City flight routes
Popular flights