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Panama City

$522+ Cheap flights from Harrisburg (MDT) to Panama City (PTY)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/11. Fares are subject to change and may not be available on all flights or dates of travel.
MDT — PTY
oct. 17 — oct. 241
vie. 10/17
vie. 10/24
1 adult, Economy
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Cheap flight deals from Harrisburg to Panama City

Discover tips and strategies to find the most affordable flight options for your journey from Harrisburg (MDT) to Panama City (PTY). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated septiembre 17, 2025.

Round-trip from

$522
(United Airlines)

Popular in

February

Cheapest in

August
From Harrisburg to Panama City Tocumen Intl
Search Deals
Highest demand for flights based on searches. 0% potential increase in price ($1 potential increase over avg. RT price).
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Cheapest flight prices on average. 3% potential price decrease ($21 potential savings vs. average RT price).
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Find flight deals from Harrisburg to Panama City

Cheapest flights from Harrisburg to Panama City
Explore the most affordable flight options available from Harrisburg to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on septiembre 17, 2025.

This United Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 10/116:15 amMDT - PTY
2 stops13h 22mUnited Airlines
mar. 10/2110:00 amPTY - MDT
2 stops22h 29mUnited Airlines
Deal found 9/17$522
This Delta deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 10/136:00 amMDT - PTY
1 stop7h 56mDelta
jue. 10/162:21 pmPTY - MDT
1 stop7h 47mDelta
Deal found 9/14$544
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 10/135:01 pmMDT - PTY
2 stops22h 02mAmerican Airlines
jue. 10/163:15 pmPTY - MDT
2 stops19h 25mAmerican Airlines
Deal found 9/14$632
This Delta deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 10/116:00 amMDT - PTY
1 stop7h 56mDelta
mar. 10/212:21 pmPTY - MDT
1 stop7h 47mDelta
Deal found 9/17$721
This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 10/302:35 pmMDT - PTY
1 stop16h 38mUnited Airlines
jue. 11/69:11 amPTY - MDT
1 stop9h 44mUnited Airlines
Deal found 9/15$4,653

Cheapflights Fare Finder

 
Customize your flight search to find flights from Harrisburg to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated septiembre 17, 2025.
Use the filters below to find and compare flights from Harrisburg to Panama City that are best for you.

Fly from

Harrisburg

Fly to

Panama City

Route

Depart

Return

Price

HarrisburgPanama City

MDT - PTY

MDTPTY

Harrisburg

jue. 10/30

2:35 pm-1:45 pm

2 stops24h 10m

Panama City Tocumen Intl

jue. 11/6

8:55 am-9:35 am

2 stops24h 40m

$522

HarrisburgPanama City

MDT - PTY

MDTPTY

Harrisburg

sáb. 10/11

6:15 am-6:37 pm

2 stops13h 22m

Panama City Tocumen Intl

mar. 10/21

10:00 am-9:29 am

2 stops22h 29m

$522

HarrisburgPanama City

MDT - PTY

MDTPTY

Harrisburg

lun. 10/13

6:00 am-12:56 pm

1 stop7h 56m

Panama City Tocumen Intl

jue. 10/16

2:21 pm-11:08 pm

1 stop7h 47m

$544

HarrisburgPanama City

MDT - PTY

MDTPTY

Harrisburg

lun. 10/13

5:01 pm-2:03 pm

2 stops22h 02m

Panama City Tocumen Intl

jue. 10/16

3:15 pm-11:40 am

2 stops19h 25m

$632

HarrisburgPanama City

MDT - PTY

MDTPTY

Harrisburg

sáb. 10/11

6:00 am-12:56 pm

1 stop7h 56m

Panama City Tocumen Intl

mar. 10/21

2:21 pm-11:08 pm

1 stop7h 47m

$721

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/15

Best time to book a flight from Harrisburg to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Harrisburg with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Harrisburg to Panama City

What is the cheapest month to book a flight from Harrisburg to Panama City?

Currently, October is the cheapest month in which you can book a flight from Harrisburg to Panama City (average of $478). Flying from Harrisburg to Panama City in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MDT to PTY?

Find hourly flight availability from Harrisburg to Panama City. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated septiembre 17, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Harrisburg to Panama City as you normally would.

Reviews of airlines servicing Panama City

Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated septiembre 17, 2025.
Peruse reviews from past customers who have flown with Delta and American Airlines from Harrisburg to Panama City to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,961 reviews

Entertainment

7.9

Overall

8.0

Boarding

8.2

Comfort

7.9

Crew

8.5

Food

7.3

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,961 reviews
Delta
8.0
Very good
7,961 reviews

Entertainment

7.9

Overall

8.0

Boarding

8.2

Comfort

7.9

Crew

8.5

Food

7.3

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,961 reviews

Entertainment

7.9

Overall

8.0

Boarding

8.2

Comfort

7.9

Crew

8.5

Food

7.3

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from Harrisburg to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Harrisburg to Panama City?

    A quick flight from Harrisburg to Panama City can take about 7h 56m. United Airlines provides one of the quickest options available for as low as $544. Harrisburg and Panama City are separated by a distance of 2155 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines flying from Harrisburg to Panama City round-trip?

    Cheapflights users have booked flights from Harrisburg to Panama City round-trip from $501. Another airline that can offer you cheap pricing is Delta. American Airlines is priced at 22% lower than the current average price of a flight leaving 3 months from now.

  • Can I find deals for flights from Harrisburg to Panama City that include hotel bookings?

    Yes. In addition to deals on Harrisburg to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Harrisburg to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Harrisburg to Panama City.

  • Can I find deals for business class flights from Harrisburg to Panama City?

    Yes. Cheapflights offers flight deals from Harrisburg to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Harrisburg to Panama City?

    Currently, October is the cheapest month in which you can book a flight from Harrisburg to Panama City (average of $478). Flying from Harrisburg to Panama City in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Top 2 airlines flying from Harrisburg to Panama City

Discover the top 2 airlines that operate flights from Harrisburg to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated septiembre 17, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$501Average$546FlexibilityNo cancel feeOn-time71%
DeltaCheapest$531Average$770FlexibilityNo cancel feeOn-timeN/A

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