HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Panama City

$282+ Cheap flights from Harrisburg (MDT) to Panama City (PTY)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/28. Fares are subject to change and may not be available on all flights or dates of travel.
MDT — PTY
Apr 21 — Apr 281
Tue 4/21
Tue 4/28
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Harrisburg to Panama City with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Harrisburg to Panama City

Cheapest flights from Harrisburg to Panama City
Explore the most affordable flight options available from Harrisburg to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 22, 2026.

This United Airlines deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/66:00 am
MDT
-
PTY
2 stops11h 07m
United Airlines
Tue 12/811:35 am
PTY
-
MDT
2 stops22h 20m
United Airlines
Deal found 3/19$630
This United Airlines deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/286:15 am
MDT
-
PTY
2 stops10h 57m
United Airlines
Sun 5/310:55 pm
PTY
-
MDT
2 stops16h 58m
United Airlines
Deal found 3/22$633
This American Airlines deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/145:43 pm
MDT
-
PTY
2 stops19h 30m
American Airlines
Fri 6/191:14 pm
PTY
-
MDT
2 stops19h 54m
American Airlines
Deal found 3/21$730
This Delta deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/146:04 am
MDT
-
PTY
1 stop8h 05m
Delta
Fri 6/192:24 pm
PTY
-
MDT
1 stop8h 31m
Delta
Deal found 3/21$1,304
This Avianca deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/66:00 am
MDT
-
PTY
2 stops28h 30m
Avianca
Tue 12/811:25 am
PTY
-
MDT
3 stops26h 24m
Avianca
Deal found 3/19$5,201
This United Airlines deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/1410:30 am
MDT
-
PTY
2 stops10h 16m
United Airlines
Fri 6/199:13 am
PTY
-
MDT
1 stop13h 17m
United Airlines
Deal found 3/21$7,855
This United Airlines deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/26:15 am
MDT
-
PTY
1 stop15h 26m
United Airlines
Sat 5/97:25 pm
PTY
-
MDT
1 stop17h 08m
United Airlines
Deal found 3/17$7,862

Find flight deals from Harrisburg to Panama City

Discover tips and strategies to find the most affordable flight options for your journey from Harrisburg (MDT) to Panama City (PTY). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated March 22, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$630
(United Airlines)

One-way from

$282
(United Airlines)
Provider with most accurate pricing for Harrisburg-Panama City Tocumen Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Harrisburg-Panama City Tocumen Intl flights.
Search Deals
From Harrisburg to Panama City Tocumen Intl
Search Deals
One-way flight from Harrisburg to Panama City Tocumen Intl
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Harrisburg to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 22, 2026.
Use the filters below to find and compare flights from Harrisburg to Panama City that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

HarrisburgPanama City

MDT - PTY

MDTPTY

Harrisburg

Mon 5/4

5:54 pm-4:12 pm

2 stops23h 18m

Panama City Tocumen Intl

Mon 5/11

7:55 am-9:44 am

2 stops24h 49m

$630

HarrisburgPanama City

MDT - PTY

MDTPTY

Harrisburg

Wed 5/6

6:30 am-6:37 pm

2 stops13h 07m

Panama City Tocumen Intl

Wed 5/13

9:45 am-11:28 pm

2 stops12h 43m

$630

HarrisburgPanama City

MDT - PTY

MDTPTY

Harrisburg

Tue 4/28

6:15 am-4:12 pm

2 stops10h 57m

Panama City Tocumen Intl

Sun 5/3

10:55 pm-4:53 pm

2 stops16h 58m

$633

HarrisburgPanama City

MDT - PTY

MDTPTY

Harrisburg

Sat 5/2

6:15 am-7:31 pm

2 stops14h 16m

Panama City Tocumen Intl

Sat 5/9

10:55 pm-1:33 pm

2 stops13h 38m

$633

HarrisburgPanama City

MDT - PTY

MDTPTY

Harrisburg

Sun 6/14

5:43 pm-12:13 pm

2 stops19h 30m

Panama City Tocumen Intl

Fri 6/19

1:14 pm-10:08 am

2 stops19h 54m

$730
Quickest round-trip

HarrisburgPanama City

MDT - PTY

MDTPTY

Harrisburg

Sun 6/14

6:04 am-1:09 pm

1 stop8h 05m

Panama City Tocumen Intl

Fri 6/19

2:24 pm-11:55 pm

1 stop8h 31m

$1,304

HarrisburgPanama City

MDT - PTY

MDTPTY

Harrisburg

Sun 6/14

10:30 am-7:46 pm

2 stops10h 16m

Panama City Tocumen Intl

Fri 6/19

9:13 am-11:30 pm

1 stop13h 17m

$7,855
Cheapest one-way
Quickest one-way

HarrisburgPanama City

MDT - PTY

MDTPTY

Harrisburg

Thu 5/28

8:15 am-7:31 pm

2 stops12h 16m

$282

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/18

Sorted by cheapest first

Compare providers for flights from Harrisburg to Panama City

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Harrisburg to Panama City in March.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Harrisburg-Panama City flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Harrisburg-Panama City flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Harrisburg-Panama City flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Harrisburg-Panama City flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Harrisburg-Panama City flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Harrisburg to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Harrisburg with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Harrisburg to Panama City

What is the cheapest month to book a flight from Harrisburg to Panama City?

Currently, December is the cheapest month in which you can book a flight from Harrisburg to Panama City (average of $340). Flying from Harrisburg to Panama City in January is currently the most expensive (average of $477). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Panama City

Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated March 22, 2026.
Peruse reviews from past customers who have flown with Delta from Harrisburg to Panama City to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,314 reviews

Comfort

7.9

Boarding

8.1

Overall

7.9

Food

7.2

Entertainment

7.8

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,314 reviews
Delta
7.9
Good
8,314 reviews

Comfort

7.9

Boarding

8.1

Overall

7.9

Food

7.2

Entertainment

7.8

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Harrisburg to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Harrisburg to Panama City?

    A quick flight from Harrisburg to Panama City can take about 19h 30m. United Airlines provides one of the quickest options available for as low as $730. Harrisburg and Panama City are separated by a distance of 2155 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What is the cheapest airline to fly from Harrisburg to Panama City round-trip?

    Cheapflights users have booked flights from Harrisburg to Panama City round-trip from $216.

  • Can I find deals for flights from Harrisburg to Panama City that include hotel bookings?

    Yes. In addition to deals on Harrisburg to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Harrisburg to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Harrisburg to Panama City.

  • Can I find deals for business class flights from Harrisburg to Panama City?

    Yes. Cheapflights offers flight deals from Harrisburg to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Harrisburg to Panama City?

    Currently, December is the cheapest month in which you can book a flight from Harrisburg to Panama City (average of $340). Flying from Harrisburg to Panama City in January is currently the most expensive (average of $477). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Top airline flying from Harrisburg to Panama City

Discover the top airline that operate flights from Harrisburg to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 22, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$216Average$628FlexibilityNo cancel feeOn-timeN/A

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.