$480+ Cheap flights from Harrisburg (MDT) to Panama City (PTY)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/1. Fares are subject to change and may not be available on all flights or dates of travel.
MDT — PTY
Oct 24 — Oct 311
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from Harrisburg to Panama City with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Harrisburg to Panama City
Cheapest
Best
Last-minute
One-way
Cheapest flights from Harrisburg to Panama CityExplore the most affordable flight options available from Harrisburg to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 24, 2026.
Explore the most affordable flight options available from Harrisburg to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 24, 2026.
This United Airlines deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/195:54 pm -
2 stops26h 37m
Sat 10/319:30 am -
2 stops24h 23m
Deal found 9/21![United Airlines logo]()
$755
This United Airlines deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/75:41 pm -
2 stops21h 04m
Sat 11/144:41 pm -
2 stops20h 43m
Deal found 9/22![United Airlines logo]()
$814
This American Airlines deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/207:16 pm -
2 stops20h 17m
Sat 1/22:51 pm -
2 stops23h 47m
Deal found 9/20![American Airlines logo]()
$1,926
This Delta deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/206:00 am -
1 stop15h 45m
Sat 1/23:28 pm -
1 stop8h 28m
Deal found 9/20![Delta logo]()
$2,085
This KAYAK deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/196:15 am -
1 stop8h 16m
Sat 10/313:41 pm -
2 stops18h 12m
Deal found 9/21![Copa Airlines logo]()
$2,913
Best flights from Harrisburg to Panama CityDiscover carefully curated flight deals from Harrisburg to Panama City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 24, 2026.
Discover carefully curated flight deals from Harrisburg to Panama City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 24, 2026.
This American Airlines deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/164:52 pm -
2 stops20h 33m
Thu 1/214:55 pm -
2 stops20h 35m
Deal found 9/22![American Airlines logo]()
$665
This United Airlines deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/195:54 pm -
2 stops26h 37m
Sat 10/319:30 am -
2 stops24h 23m
Deal found 9/21![United Airlines logo]()
$755
This Delta deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/166:00 am -
1 stop7h 55m
Thu 1/213:20 pm -
1 stop8h 18m
Deal found 9/22![Delta logo]()
$1,165
This United Airlines deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/75:41 pm -
2 stops21h 04m
Sat 11/144:41 pm -
2 stops20h 43m
Deal found 9/22![United Airlines logo]()
$814
This KAYAK deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/196:15 am -
1 stop8h 16m
Sat 10/313:41 pm -
2 stops18h 12m
Deal found 9/21![Copa Airlines logo]()
$2,913
This Delta deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/206:00 am -
1 stop15h 45m
Sat 1/23:28 pm -
1 stop8h 28m
Deal found 9/20![Delta logo]()
$2,085
This American Airlines deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/206:00 am -
2 stops9h 33m
Sat 1/24:33 pm -
3 stops16h 48m
Deal found 9/20![American Airlines logo]()
$5,249
Last-minute flights from Harrisburg to Panama CityDiscover last-minute flight deals from Harrisburg to Panama City. Data last updated September 24, 2026 and is based on user searches.
Discover last-minute flight deals from Harrisburg to Panama City. Data last updated September 24, 2026 and is based on user searches.
This United Airlines deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/195:54 pm -
2 stops26h 37m
Sat 10/319:30 am -
2 stops24h 23m
Deal found 9/21![United Airlines logo]()
$755
This KAYAK deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/196:15 am -
1 stop8h 16m
Sat 10/313:41 pm -
2 stops18h 12m
Deal found 9/21![Copa Airlines logo]()
$2,913
One-way flights from Harrisburg to Panama CitySearch for one-way flight options from Harrisburg to Panama City. Find affordable one-way fares based on user searches. Data last updated September 24, 2026.
Search for one-way flight options from Harrisburg to Panama City. Find affordable one-way fares based on user searches. Data last updated September 24, 2026.
This United Airlines deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/16:15 am -
2 stops14h 16m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/21![United Airlines logo]()
$480
This Kiwi.com deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/18:53 pm -
3 stops28h 42m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/21![Multiple Airlines logo]()
$598
Find flight deals from Harrisburg to Panama City
Discover tips and strategies to find the most affordable flight options for your journey from Harrisburg (MDT) to Panama City (PTY). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 24, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $665 (American Airlines) |
One-way from | $315 (United Airlines) |
Cheapflights Fare Finder
Customize your flight search to find flights from Harrisburg to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 24, 2026.
Use the filters below to find and compare flights from Harrisburg to Panama City that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
HarrisburgPanama City
MDT Harrisburg - PTY Panama City Tocumen Intl
MDTPTY
Harrisburg
Thu 10/1
6:15 am-7:31 pm
2 stops14h 16m
Panama City Tocumen Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$480
HarrisburgPanama City
MDT Harrisburg - PTY Panama City Tocumen Intl
MDTPTY
Harrisburg
Thu 10/1
8:53 pm-12:35 am
3 stops28h 42m
Panama City Tocumen Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$598
HarrisburgPanama City
MDT Harrisburg - PTY Panama City Tocumen Intl
MDTPTY
Harrisburg
Sat 1/16
4:52 pm-1:25 pm
2 stops20h 33m
Panama City Tocumen Intl
Thu 1/21
4:55 pm-1:30 pm
2 stops20h 35m
$665
HarrisburgPanama City
MDT Harrisburg - PTY Panama City Tocumen Intl
MDTPTY
Harrisburg
Mon 10/19
5:54 pm-7:31 pm
2 stops26h 37m
Panama City Tocumen Intl
Sat 10/31
9:30 am-10:53 am
2 stops24h 23m
$755
HarrisburgPanama City
MDT Harrisburg - PTY Panama City Tocumen Intl
MDTPTY
Harrisburg
Sat 11/7
5:41 pm-2:45 pm
2 stops21h 04m
Panama City Tocumen Intl
Sat 11/14
4:41 pm-1:24 pm
2 stops20h 43m
$814
HarrisburgPanama City
MDT Harrisburg - PTY Panama City Tocumen Intl
MDTPTY
Harrisburg
Sat 1/16
6:00 am-1:55 pm
1 stop7h 55m
Panama City Tocumen Intl
Thu 1/21
3:20 pm-11:38 pm
1 stop8h 18m
$1,165
HarrisburgPanama City
MDT Harrisburg - PTY Panama City Tocumen Intl
MDTPTY
Harrisburg
Sun 12/20
6:00 am-9:45 pm
1 stop15h 45m
Panama City Tocumen Intl
Sat 1/2
3:28 pm-11:56 pm
1 stop8h 28m
$2,085
HarrisburgPanama City
MDT Harrisburg - PTY Panama City Tocumen Intl
MDTPTY
Harrisburg
Mon 10/19
6:15 am-1:31 pm
1 stop8h 16m
Panama City Tocumen Intl
Sat 10/31
3:41 pm-10:53 am
2 stops18h 12m
$2,913
HarrisburgPanama City
MDT Harrisburg - PTY Panama City Tocumen Intl
MDTPTY
Harrisburg
Sun 12/20
6:00 am-3:33 pm
2 stops9h 33m
Panama City Tocumen Intl
Sat 1/2
4:33 pm-9:21 am
3 stops16h 48m
$5,249
Sorted by cheapest first
Compare providers for flights from Harrisburg to Panama City
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Harrisburg to Panama City in September.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Harrisburg-Panama City flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Harrisburg-Panama City flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Harrisburg-Panama City flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Harrisburg-Panama City flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Harrisburg-Panama City flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Harrisburg to Panama City
Have a flexible travel schedule? Discover the best time to fly to Panama City from Harrisburg with our price prediction graph.
MDT-PTY
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Related info for your journey
Find useful and relevant information for your journey from Harrisburg to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
Other flight options
Panama City flight routes
Popular flights