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Panama City

$522+ Cheap flights from Harrisburg (MDT) to Panama City (PTY)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/24. Fares are subject to change and may not be available on all flights or dates of travel.
MDT — PTY
Jan 23 — Jan 301
Fri 1/23
Fri 1/30
1 adult, Economy
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Cheap flight deals from Harrisburg to Panama City

Cheapest flights from Harrisburg to Panama City
Explore the most affordable flight options available from Harrisburg to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 24, 2025.

This United Airlines deal was found by Cheapflights users on 12/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/246:30 amMDT - PTY
2 stops13h 08mUnited Airlines
Sun 12/2811:55 pmPTY - MDT
2 stops19h 03mUnited Airlines
Deal found 12/24$522
This Delta deal was found by Cheapflights users on 12/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/246:00 amMDT - PTY
2 stops14h 00mDelta
Sat 12/278:00 amPTY - MDT
2 stops15h 02mDelta
Deal found 12/23$568
This American Airlines deal was found by Cheapflights users on 12/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/267:34 pmMDT - PTY
2 stops20h 20mAmerican Airlines
Tue 12/304:55 pmPTY - MDT
2 stops20h 22mAmerican Airlines
Deal found 12/24$699
This United Airlines deal was found by Cheapflights users on 12/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/263:00 pmMDT - PTY
2 stops22h 55mUnited Airlines
Tue 12/3011:35 amPTY - MDT
2 stops22h 38mUnited Airlines
Deal found 12/24$721
This Delta deal was found by Cheapflights users on 12/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/241:34 pmMDT - PTY
2 stops24h 23mDelta
Sun 12/283:22 pmPTY - MDT
1 stop8h 14mDelta
Deal found 12/24$801
This Delta deal was found by Cheapflights users on 12/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/266:00 amMDT - PTY
1 stop7h 57mDelta
Mon 12/298:00 amPTY - MDT
1 stop9h 11mDelta
Deal found 12/24$1,356
This Mytrip deal was found by Cheapflights users on 12/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/244:28 pmMDT - PTY
3 stops32h 32mMultiple Airlines
Sat 12/2711:25 amPTY - MDT
3 stops24h 15mMultiple Airlines
Deal found 12/23$1,384
This Delta deal was found by Cheapflights users on 12/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/2612:21 pmMDT - PTY
1 stop7h 39mDelta
Tue 12/308:00 amPTY - MDT
1 stop15h 36mDelta
Deal found 12/24$1,420
This Kiwi.com deal was found by Cheapflights users on 12/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/246:54 pmMDT - PTY
1 stop23h 01mMultiple Airlines
Sun 12/285:51 pmPTY - MDT
1 stop20h 16mMultiple Airlines
Deal found 12/24$1,585

Find flight deals from Harrisburg to Panama City

Discover tips and strategies to find the most affordable flight options for your journey from Harrisburg (MDT) to Panama City (PTY). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated December 24, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$522
(United Airlines)

Popular in

December

Cheapest in

August

Average price

$905
Provider with most accurate pricing for Harrisburg-Panama City Tocumen Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Harrisburg-Panama City Tocumen Intl flights.
Search Deals
From Harrisburg to Panama City Tocumen Intl
Search Deals
Highest demand for flights based on searches. 11% potential increase in price ($86 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 4% potential price decrease ($28 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Harrisburg to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 24, 2025.
Use the filters below to find and compare flights from Harrisburg to Panama City that are best for you.

Fly from

Harrisburg

Fly to

Panama City

Route

Depart

Return

Price

HarrisburgPanama City

MDT - PTY

MDTPTY

Harrisburg

Sat 2/7

5:26 pm-5:07 pm

2 stops23h 41m

Panama City Tocumen Intl

Tue 2/10

4:41 pm-4:34 pm

2 stops23h 53m

$522

HarrisburgPanama City

MDT - PTY

MDTPTY

Harrisburg

Fri 2/6

6:30 am-8:02 pm

2 stops13h 32m

Panama City Tocumen Intl

Fri 2/13

4:41 pm-1:56 pm

2 stops21h 15m

$522

HarrisburgPanama City

MDT - PTY

MDTPTY

Harrisburg

Mon 5/4

5:31 pm-2:14 pm

2 stops21h 43m

Panama City Tocumen Intl

Sun 5/10

9:45 am-11:27 pm

2 stops12h 42m

$522

HarrisburgPanama City

MDT - PTY

MDTPTY

Harrisburg

Thu 1/8

3:10 pm-2:45 pm

2 stops23h 35m

Panama City Tocumen Intl

Sun 1/11

4:41 pm-10:13 am

2 stops17h 32m

$568

HarrisburgPanama City

MDT - PTY

MDTPTY

Harrisburg

Fri 2/6

6:30 am-8:02 pm

2 stops13h 32m

Panama City Tocumen Intl

Tue 2/10

4:41 pm-1:51 pm

2 stops21h 10m

$568

HarrisburgPanama City

MDT - PTY

MDTPTY

Harrisburg

Wed 1/7

6:15 am-5:07 pm

2 stops10h 52m

Panama City Tocumen Intl

Sun 1/11

4:41 pm-2:15 pm

2 stops21h 34m

$568

HarrisburgPanama City

MDT - PTY

MDTPTY

Harrisburg

Mon 5/4

6:00 am-12:55 pm

1 stop7h 55m

Panama City Tocumen Intl

Sun 5/10

2:20 pm-11:41 pm

1 stop8h 21m

$674

HarrisburgPanama City

MDT - PTY

MDTPTY

Harrisburg

Thu 1/8

6:00 am-1:55 pm

1 stop7h 55m

Panama City Tocumen Intl

Sun 1/11

3:20 pm-11:26 pm

1 stop8h 06m

$918

HarrisburgPanama City

MDT - PTY

MDTPTY

Harrisburg

Wed 1/7

6:00 am-1:55 pm

1 stop7h 55m

Panama City Tocumen Intl

Sun 1/11

3:20 pm-11:26 pm

1 stop8h 06m

$918

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/22

Compare providers for flights from Harrisburg to Panama City

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Harrisburg to Panama City in December.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
eDreamsPrice Accuracy3 starsTrust Score*3 stars
AranGrantPrice Accuracy2 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Harrisburg-Panama City flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Harrisburg-Panama City flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Harrisburg-Panama City flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Harrisburg-Panama City flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Harrisburg-Panama City flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Harrisburg to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Harrisburg with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Harrisburg to Panama City

What is the cheapest month to book a flight from Harrisburg to Panama City?

Currently, June is the cheapest month in which you can book a flight from Harrisburg to Panama City (average of $265). Flying from Harrisburg to Panama City in August is currently the most expensive (average of $471). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Harrisburg to Panama City?

Reviews of airlines servicing Panama City

Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated December 24, 2025.
Peruse reviews from past customers who have flown with Delta and American Airlines from Harrisburg to Panama City to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,011 reviews

Comfort

7.9

Crew

8.5

Boarding

8.1

Entertainment

7.9

Overall

7.9

Food

7.3

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,011 reviews
Delta
7.9
Good
8,011 reviews

Comfort

7.9

Crew

8.5

Boarding

8.1

Entertainment

7.9

Overall

7.9

Food

7.3

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,056 reviews
Delta
7.9
Good
8,011 reviews

Comfort

7.9

Crew

8.5

Boarding

8.1

Entertainment

7.9

Overall

7.9

Food

7.3

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Harrisburg to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Harrisburg to Panama City?

    A quick flight from Harrisburg to Panama City can take about 23h 41m. United Airlines provides one of the quickest options available for as low as $522. Harrisburg and Panama City are separated by a distance of 2155 mi.

  • What are the cheapest airlines flying from Harrisburg to Panama City round-trip?

    Cheapflights users have booked flights from Harrisburg to Panama City round-trip from $491. Another airline that can offer you cheap pricing is American Airlines. Delta is priced at 25% lower than the current average price of a flight leaving 3 months from now.

  • Can I find deals for flights from Harrisburg to Panama City that include hotel bookings?

    Yes. In addition to deals on Harrisburg to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Harrisburg to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Harrisburg to Panama City.

  • Can I find deals for business class flights from Harrisburg to Panama City?

    Yes. Cheapflights offers flight deals from Harrisburg to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Harrisburg to Panama City?

    Currently, June is the cheapest month in which you can book a flight from Harrisburg to Panama City (average of $265). Flying from Harrisburg to Panama City in August is currently the most expensive (average of $471). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Top 2 airlines flying from Harrisburg to Panama City

Discover the top 2 airlines that operate flights from Harrisburg to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 24, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$491Average$699FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$501Average$546FlexibilityNo cancel feeOn-time71%

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