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Panama City

$627+ Cheap flights from Harrisburg (MDT) to Panama City (PTY)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/10. Fares are subject to change and may not be available on all flights or dates of travel.
MDT — PTY
May 17 — May 241
Sun 5/17
Sun 5/24
1 adult, Economy
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Cheap flight deals from Harrisburg to Panama City

Cheapest flights from Harrisburg to Panama City
Explore the most affordable flight options available from Harrisburg to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 17, 2026.

This American Airlines deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/107:40 pm
MDT
-
PTY
2 stops17h 34m
American Airlines
Fri 7/311:14 pm
PTY
-
MDT
2 stops20h 53m
American Airlines
Deal found 4/13$627
This American Airlines deal was found by Cheapflights users on 4/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/277:17 pm
MDT
-
PTY
2 stops17h 57m
American Airlines
Wed 6/31:14 pm
PTY
-
MDT
2 stops19h 54m
American Airlines
Deal found 4/12$647
This American Airlines deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/182:45 pm
MDT
-
PTY
2 stops22h 39m
American Airlines
Sat 8/221:24 pm
PTY
-
MDT
2 stops20h 52m
American Airlines
Deal found 4/16$650
This United Airlines deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/286:30 am
MDT
-
PTY
2 stops14h 01m
United Airlines
Thu 6/47:55 am
PTY
-
MDT
2 stops14h 35m
United Airlines
Deal found 4/13$660
This American Airlines deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/117:40 pm
MDT
-
PTY
2 stops17h 34m
American Airlines
Fri 7/311:14 pm
PTY
-
MDT
2 stops19h 54m
American Airlines
Deal found 4/13$747
This United Airlines deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/75:31 pm
MDT
-
PTY
2 stops21h 14m
United Airlines
Wed 12/94:41 pm
PTY
-
MDT
2 stops17h 14m
United Airlines
Deal found 4/15$770
This Delta deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/186:00 am
MDT
-
PTY
1 stop8h 13m
Delta
Sat 8/222:28 pm
PTY
-
MDT
1 stop8h 12m
Delta
Deal found 4/16$803
This Delta deal was found by Cheapflights users on 4/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/276:00 am
MDT
-
PTY
1 stop7h 50m
Delta
Wed 6/32:15 pm
PTY
-
MDT
1 stop8h 36m
Delta
Deal found 4/12$833
This Delta deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/96:04 am
MDT
-
PTY
1 stop8h 05m
Delta
Fri 7/312:24 pm
PTY
-
MDT
2 stops20h 07m
Delta
Deal found 4/13$837
This Delta deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/1011:56 am
MDT
-
PTY
1 stop26h 13m
Delta
Fri 7/312:24 pm
PTY
-
MDT
2 stops20h 07m
Delta
Deal found 4/13$849

Find flight deals from Harrisburg to Panama City

Discover tips and strategies to find the most affordable flight options for your journey from Harrisburg (MDT) to Panama City (PTY). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated April 17, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$627
(American Airlines)
Provider with most accurate pricing for Harrisburg-Panama City Tocumen Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Harrisburg-Panama City Tocumen Intl flights.
Search Deals
From Harrisburg to Panama City Tocumen Intl
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Harrisburg to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 17, 2026.
Use the filters below to find and compare flights from Harrisburg to Panama City that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

HarrisburgPanama City

MDT - PTY

MDTPTY

Harrisburg

Wed 5/27

7:17 pm-12:14 pm

2 stops17h 57m

Panama City Tocumen Intl

Wed 6/3

1:14 pm-10:08 am

2 stops19h 54m

$647

HarrisburgPanama City

MDT - PTY

MDTPTY

Harrisburg

Tue 8/18

2:45 pm-12:24 pm

2 stops22h 39m

Panama City Tocumen Intl

Sat 8/22

1:24 pm-11:16 am

2 stops20h 52m

$650

HarrisburgPanama City

MDT - PTY

MDTPTY

Harrisburg

Thu 5/28

6:30 am-7:31 pm

2 stops14h 01m

Panama City Tocumen Intl

Thu 6/4

7:55 am-11:30 pm

2 stops14h 35m

$660
Quickest round-trip

HarrisburgPanama City

MDT - PTY

MDTPTY

Harrisburg

Tue 8/18

6:00 am-1:13 pm

1 stop8h 13m

Panama City Tocumen Intl

Sat 8/22

2:28 pm-11:40 pm

1 stop8h 12m

$803

HarrisburgPanama City

MDT - PTY

MDTPTY

Harrisburg

Wed 5/27

6:00 am-12:50 pm

1 stop7h 50m

Panama City Tocumen Intl

Wed 6/3

2:15 pm-11:51 pm

1 stop8h 36m

$833

HarrisburgPanama City

MDT - PTY

MDTPTY

Harrisburg

Tue 6/9

6:04 am-1:09 pm

1 stop8h 05m

Panama City Tocumen Intl

Fri 7/31

2:24 pm-11:31 am

2 stops20h 07m

$837

HarrisburgPanama City

MDT - PTY

MDTPTY

Harrisburg

Wed 7/8

6:30 am-6:37 pm

2 stops13h 07m

Panama City Tocumen Intl

Thu 7/9

10:55 pm-1:42 pm

2 stops13h 47m

$1,028

HarrisburgPanama City

MDT - PTY

MDTPTY

Harrisburg

Wed 5/27

7:18 pm-8:35 pm

2 stops26h 17m

Panama City Tocumen Intl

Wed 6/3

12:03 pm-5:08 pm

1 stop28h 05m

$1,304

HarrisburgPanama City

MDT - PTY

MDTPTY

Harrisburg

Tue 8/18

10:30 am-7:31 pm

2 stops10h 01m

Panama City Tocumen Intl

Sat 8/22

10:29 pm-2:03 pm

1 stop14h 34m

$4,712

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/12

Sorted by cheapest first

Compare providers for flights from Harrisburg to Panama City

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Harrisburg to Panama City in April.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Harrisburg-Panama City flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Harrisburg-Panama City flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Harrisburg-Panama City flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Harrisburg-Panama City flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Harrisburg-Panama City flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Harrisburg to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Harrisburg with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Related info for your journey

Find useful and relevant information for your journey from Harrisburg to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Harrisburg to Panama City?

    A quick flight from Harrisburg to Panama City can take about 8h 13m. American Airlines provides one of the quickest options available for as low as $803. Harrisburg and Panama City are separated by a distance of 2155 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • Can I find deals for flights from Harrisburg to Panama City that include hotel bookings?

    Yes. In addition to deals on Harrisburg to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Harrisburg to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Harrisburg to Panama City.

  • Can I find deals for business class flights from Harrisburg to Panama City?

    Yes. Cheapflights offers flight deals from Harrisburg to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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