Check security wait times on the IAH website to plan your arrival and avoid delays.

Most accurate provider | eDreams 3 stars |
|---|---|
Most trusted provider | eDreams 3 stars |
Round-trip from | $411 (Kiwi.com) |
One-way from | $165 (Kiwi.com) |
Popular in | December |
Cheapest in | November |
Average price | $789 |
Good round-trip deal | $628 or less |
Good one-way deal | $326 or less |
Fly from
Fly to
Route
Depart
Return
Price
HoustonPanama City
IAH - PTY
IAHPTY
Houston George Bush Intcntl
Thu 12/11
9:30 am-6:55 pm
1 stop8h 25m
Panama City Tocumen Intl
Wed 12/17
7:50 pm-4:35 pm
1 stop21h 45m
HoustonPanama City
IAH - PTY
IAHPTY
Houston George Bush Intcntl
Wed 12/10
9:30 am-6:55 pm
1 stop8h 25m
Panama City Tocumen Intl
Wed 12/17
7:50 pm-4:35 pm
1 stop21h 45m
HoustonPanama City
IAH - PTY
IAHPTY
Houston George Bush Intcntl
Thu 5/14
3:41 pm-9:10 pm
3 stops29h 29m
Panama City Tocumen Intl
Sun 5/17
3:20 am-2:17 pm
3 stops34h 57m
HoustonPanama City
IAH - PTY
IAHPTY
Houston George Bush Intcntl
Mon 12/15
6:14 am-10:30 am
3 stops27h 16m
Panama City Tocumen Intl
Tue 12/23
9:45 am-4:35 pm
2 stops31h 50m
HoustonPanama City
IAH - PTY
IAHPTY
Houston George Bush Intcntl
Sat 1/31
4:35 pm-8:50 am
2 stops15h 15m
Panama City Tocumen Intl
Sat 2/7
2:55 am-3:10 pm
2 stops13h 15m
HoustonPanama City
IAH - PTY
IAHPTY
Houston George Bush Intcntl
Tue 1/6
5:54 am-10:30 am
3 stops27h 36m
Panama City Tocumen Intl
Thu 1/8
2:55 am-3:19 pm
3 stops37h 24m
HoustonPanama City
IAH - PTY
IAHPTY
Houston George Bush Intcntl
Thu 2/19
9:34 am-2:45 pm
Nonstop4h 11m
Panama City Tocumen Intl
Thu 2/26
11:35 am-2:54 pm
Nonstop4h 19m
HoustonPanama City
IAH - PTY
IAHPTY
Houston George Bush Intcntl
Tue 3/10
9:34 am-1:45 pm
Nonstop4h 11m
Panama City Tocumen Intl
Wed 3/18
11:35 am-3:54 pm
Nonstop4h 19m
HoustonPanama City
IAH - PTY
IAHPTY
Houston George Bush Intcntl
Thu 2/19
1:00 pm-8:50 am
2 stops18h 50m
Panama City Tocumen Intl
Sun 2/22
2:55 am-3:10 pm
2 stops13h 15m
HoustonPanama City
IAH - PTY
IAHPTY
Houston George Bush Intcntl
Tue 3/10
6:00 am-12:55 pm
1 stop6h 55m
Panama City Tocumen Intl
Wed 3/18
2:20 pm-11:59 pm
1 stop9h 39m
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy2 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*1 star | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy2 stars | Trust Score*3 stars |
To ensure you get the cheapest price possible for a flight from Houston George Bush Intcntl Airport to Panama City, you should look to book at least 59 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.
Currently, February is the cheapest month in which you can book a flight from Houston George Bush Intcntl Airport to Panama City (average of $418). Flying from Houston George Bush Intcntl Airport to Panama City in December is currently the most expensive (average of $786). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
One of the essential ways to save on airfare from Houston George Bush Intcntl Airport to Panama City is to remain as flexible as possible. Flights that are at noon tend to be the most expensive. A flight in the afternoon could potentially save you up to 45% on airfare.
About 19% of weekly flights between Houston and Panama City have experienced delays in the past year, with the average delay time being 139 minutes.
Historically, flights departing in the early afternoon are less likely to be delayed, whereas flights leaving at night tend to experience delays more often.
Thursday tends to have the lowest number of delays on this route, whereas Saturday has historically faced a higher average of delays compared to other days of the week.
Over the last year, United Airlines have had the lowest number of delays on this route, with just 19% of flights being delayed.
Crew
Comfort
Food
Overall
Entertainment
Boarding
Reviews
Juan Pablo,Sep 2025
MEX - PTY
Crew
Comfort
Food
Overall
Entertainment
Boarding
Reviews
Juan Pablo,Sep 2025
MEX - PTY
Crew
Comfort
Food
Overall
Entertainment
Boarding
Reviews
Juan Pablo,Sep 2025
MEX - PTY
Crew
Comfort
Food
Overall
Entertainment
Boarding
Reviews
Juan Pablo,Sep 2025
MEX - PTY
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$318 | Average$642 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$738 | Average$892 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$824 | Average$1,113 | FlexibilityNo cancel fee | On-time70% |