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Panama City

$209+ Cheap flights from Detroit Metropolitan Wayne County Airport (DTW) to Panama City (PTY)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/3. Fares are subject to change and may not be available on all flights or dates of travel.
DTW — PTY
Nov 28 — Dec 51
Fri 11/28
Fri 12/5
1 adult, Economy
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Cheapflights Tip: The best prices from Detroit Metropolitan Wayne County to Panama City Tocumen Intl are usually found in June or April, booked 27 days in advance, depart on a Wednesday or Monday and return on a Monday

Cheap flight deals from Detroit to Panama City

Discover tips and strategies to find the most affordable flight options for your journey from Detroit (DTW) to Panama City (PTY). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 29, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$490
(Kiwi.com)

One-way from

$209
(Kiwi.com)

Popular in

December

Cheapest in

June

Average price

$740
Provider with most accurate pricing for Detroit Metropolitan Wayne County-Panama City Tocumen Intl flight deals.
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Provider most trusted by Cheapflights users for Detroit Metropolitan Wayne County-Panama City Tocumen Intl flights.
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From Detroit Metropolitan Wayne County to Panama City Tocumen Intl
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One-way flight from Detroit Metropolitan Wayne County to Panama City Tocumen Intl
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Highest demand for flights based on searches. 13% potential increase in price ($137 potential increase over avg. RT price).
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Cheapest flight prices on average. 4% potential price decrease ($40 potential savings vs. average RT price).
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Average for round-trip flights in October 2025
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Find flight deals from Detroit to Panama City

Cheapest flights from Detroit to Panama City
Explore the most affordable flight options available from Detroit to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 29, 2025.

This Mytrip deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/310:47 amDTW - PTY
3 stops32h 08mMultiple Airlines
Sat 12/1311:25 amPTY - DTW
2 stops12h 54mMultiple Airlines
Deal found 10/28$515
This Kiwi.com deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/127:10 amDTW - PTY
2 stops27h 20mMultiple Airlines
Wed 11/1910:47 amPTY - DTW
1 stop10h 55mMultiple Airlines
Deal found 10/29$557
This Mytrip deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/183:12 pmDTW - PTY
3 stops17h 38mMultiple Airlines
Wed 11/1911:25 amPTY - DTW
2 stops12h 29mMultiple Airlines
Deal found 10/26$562
This Mytrip deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/107:17 pmDTW - PTY
2 stops23h 38mMultiple Airlines
Tue 12/25:50 pmPTY - DTW
3 stops30h 08mMultiple Airlines
Deal found 10/27$564
This Kiwi.com deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/127:10 amDTW - PTY
2 stops27h 20mMultiple Airlines
Tue 11/189:33 pmPTY - DTW
1 stop16h 56mMultiple Airlines
Deal found 10/29$570
This Mytrip deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/113:12 pmDTW - PTY
3 stops33h 28mMultiple Airlines
Tue 12/25:50 pmPTY - DTW
3 stops29h 10mMultiple Airlines
Deal found 10/27$571

Cheapflights Fare Finder

 
Customize your flight search to find flights from Detroit to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 29, 2025.
Use the filters below to find and compare flights from Detroit Metropolitan Wayne County Airport to Panama City that are best for you.

Fly from

Detroit

Fly to

Panama City

Route

Depart

Return

Price

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Tue 2/3

7:00 am-1:00 am

2 stops18h 00m

Panama City Tocumen Intl

Thu 2/5

2:55 am-9:23 pm

2 stops18h 28m

$503

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Wed 2/18

8:20 pm-8:50 am

2 stops12h 30m

Panama City Tocumen Intl

Wed 2/25

2:55 pm-10:05 am

2 stops19h 10m

$514

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Wed 12/3

10:47 am-6:55 pm

3 stops32h 08m

Panama City Tocumen Intl

Fri 12/12

2:55 am-12:09 am

3 stops21h 14m

$548

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Sun 2/15

8:20 pm-2:00 pm

2 stops17h 40m

Panama City Tocumen Intl

Sun 2/22

5:50 pm-10:05 am

2 stops16h 15m

$561

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Thu 11/13

7:10 am-1:00 am

2 stops17h 50m

Panama City Tocumen Intl

Fri 12/12

2:55 am-9:03 pm

2 stops18h 08m

$565

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Tue 11/25

6:35 am-1:00 am

2 stops18h 25m

Panama City Tocumen Intl

Mon 12/1

2:55 am-11:54 pm

2 stops20h 59m

$565

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Wed 11/12

7:10 am-10:30 am

2 stops27h 20m

Panama City Tocumen Intl

Tue 11/18

9:33 pm-2:29 pm

1 stop16h 56m

$570

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Tue 11/18

3:12 pm-8:50 am

3 stops17h 38m

Panama City Tocumen Intl

Wed 11/19

11:25 am-1:00 pm

3 stops25h 35m

$586

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Mon 11/10

7:17 pm-6:55 pm

2 stops23h 38m

Panama City Tocumen Intl

Tue 12/2

5:50 pm-2:29 pm

2 stops20h 39m

$588

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Wed 12/3

7:10 am-10:30 am

2 stops27h 20m

$209

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/27

Showing 1-10 of 12 results
1
2

Compare providers for flights from Detroit to Panama City

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Detroit to Panama City in October.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
eDreamsPrice Accuracy3 starsTrust Score*3 stars
AranGrantPrice Accuracy2 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Detroit Metropolitan Wayne County Airport-Panama City flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Detroit Metropolitan Wayne County Airport-Panama City flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Detroit Metropolitan Wayne County Airport-Panama City flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Detroit Metropolitan Wayne County Airport-Panama City flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Detroit Metropolitan Wayne County Airport-Panama City flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Detroit to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Detroit with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Detroit Metropolitan Wayne County Airport to Panama City

How far ahead should I book a flight from Detroit Metropolitan Wayne County Airport to Panama City?

Use this chart to determine the optimal time to book a round-trip flight from Detroit to Panama City. Price data was last updated on October 24, 2025.

The price you pay for your flight from Detroit Metropolitan Wayne County Airport to Panama City may vary depending on when you book. For the best chance of a lower fare, look to book 27 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

What is the cheapest month to book a flight from Detroit Metropolitan Wayne County Airport to Panama City?

Currently, June is the cheapest month in which you can book a flight from Detroit Metropolitan Wayne County Airport to Panama City (average of $594). Flying from Detroit Metropolitan Wayne County Airport to Panama City in August is currently the most expensive (average of $756). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DTW to PTY?

Find hourly flight availability from Detroit to Panama City. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 29, 2025.

It’s optimal to fly from Detroit Metropolitan Wayne County Airport to Panama City in the evening. By choosing this option you can save up to 71% on the cost of your flight, compared to a flight in the afternoon.

How much does it cost to fly round-trip from Detroit Metropolitan Wayne County Airport to Panama City?

Reviews of airlines servicing Panama City

Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated October 29, 2025.
Read reviews from past customers who have flown Delta, United Airlines, and American Airlines from Detroit Metropolitan Wayne County Airport to Panama City. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
7,992 reviews

Boarding

8.2

Overall

7.9

Entertainment

7.9

Crew

8.5

Comfort

7.9

Food

7.3

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
Delta
7.9
Good
7,992 reviews
Delta
7.9
Good
7,992 reviews

Boarding

8.2

Overall

7.9

Entertainment

7.9

Crew

8.5

Comfort

7.9

Food

7.3

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
United Airlines
7.4
Good
8,999 reviews
Delta
7.9
Good
7,992 reviews

Boarding

8.2

Overall

7.9

Entertainment

7.9

Crew

8.5

Comfort

7.9

Food

7.3

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
American Airlines
7.2
Good
11,032 reviews
Delta
7.9
Good
7,992 reviews

Boarding

8.2

Overall

7.9

Entertainment

7.9

Crew

8.5

Comfort

7.9

Food

7.3

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.

Related info for your journey

Find useful and relevant information for your journey from Detroit to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines flying from Detroit Metropolitan Wayne County Airport to Panama City round-trip?

    According to our current data, American Airlines ($578), Delta ($608), and United Airlines ($608) offers the cheapest pricing from Detroit Metropolitan Wayne County Airport to Panama City. These flights start at 34% lower than the current average price 3 months from now.

  • Can I find deals for flights from Detroit to Panama City that include hotel bookings?

    Yes. In addition to deals on Detroit to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Detroit to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Detroit to Panama City.

  • Can I find deals for business class flights from Detroit to Panama City?

    Yes. Cheapflights offers flight deals from Detroit to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Detroit Metropolitan Wayne County Airport to Panama City?

    Currently, June is the cheapest month in which you can book a flight from Detroit Metropolitan Wayne County Airport to Panama City (average of $594). Flying from Detroit Metropolitan Wayne County Airport to Panama City in August is currently the most expensive (average of $756). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Top 3 airlines flying from Detroit to Panama City

Discover the top 3 airlines that operate flights from Detroit to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 29, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$578Average$800FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$608Average$851FlexibilityNo cancel feeOn-time69%
DeltaCheapest$608Average$937FlexibilityNo cancel feeOn-timeN/A

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