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Panama City

$185+ Cheap flights from Detroit Metropolitan Wayne County Airport (DTW) to Panama City (PTY)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/25. Fares are subject to change and may not be available on all flights or dates of travel.
DTW — PTY
oct. 11 — oct. 181
sam. 10/11
sam. 10/18
1 adult, Economy
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Cheapflights Tip: The best prices from Detroit Metropolitan Wayne County to Panama City Tocumen Intl are usually found in April or June, booked 27 days in advance, depart on a Wednesday or Monday and return on a Monday

Cheap flight deals from Detroit to Panama City

Discover tips and strategies to find the most affordable flight options for your journey from Detroit (DTW) to Panama City (PTY). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated septembre 11, 2025.

Round-trip from

$419
(Avianca Connect)

One-way from

$185
(Kiwi.com)

Popular in

December

Cheapest in

April

Average price

$808
From Detroit Metropolitan Wayne County to Panama City Tocumen Intl
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One-way flight from Detroit Metropolitan Wayne County to Panama City Tocumen Intl
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Highest demand for flights based on searches. 13% potential increase in price ($134 potential increase over avg. RT price).
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Cheapest flight prices on average. 4% potential price decrease ($40 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from Detroit to Panama City

Cheapest flights from Detroit to Panama City
Explore the most affordable flight options available from Detroit to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on septembre 11, 2025.

This Kiwi.com deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sam. 10/116:17 amDTW - PTY
1 stop11h 08mMultiple Airlines
sam. 10/1810:25 amPTY - DTW
1 stop8h 35mMultiple Airlines
Deal found 9/11$472
This Avianca Connect deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca Connect is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ven. 9/196:30 amDTW - PTY
2 stops15h 40mMultiple Airlines
mar. 9/2310:05 pmPTY - DTW
2 stops21h 09mMultiple Airlines
Deal found 9/10$482
This Kiwi.com deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sam. 10/256:43 amDTW - PTY
1 stop14h 36mMultiple Airlines
sam. 11/112:03 pmPTY - DTW
1 stop10h 27mMultiple Airlines
Deal found 9/9$486
This Avianca Connect deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca Connect is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jeu. 11/137:00 amDTW - PTY
2 stops18h 00mMultiple Airlines
mar. 11/185:55 pmPTY - DTW
2 stops20h 14mMultiple Airlines
Deal found 9/10$497
This Avianca Connect deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca Connect is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jeu. 11/137:00 amDTW - PTY
2 stops18h 00mMultiple Airlines
dim. 11/162:55 amPTY - DTW
2 stops15h 59mMultiple Airlines
Deal found 9/10$503
This Avianca Connect deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca Connect is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ven. 11/1410:49 amDTW - PTY
2 stops13h 51mMultiple Airlines
dim. 11/162:55 amPTY - DTW
2 stops15h 59mMultiple Airlines
Deal found 9/10$542
This Kiwi.com deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jeu. 9/186:30 amDTW - PTY
1 stop10h 56mMultiple Airlines
jeu. 9/2510:25 amPTY - DTW
1 stop8h 49mMultiple Airlines
Deal found 9/11$545
This Avianca Connect deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca Connect is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ven. 11/77:00 amDTW - PTY
2 stops17h 40mMultiple Airlines
dim. 11/92:55 pmPTY - DTW
2 stops23h 14mMultiple Airlines
Deal found 9/10$558
This Avianca Connect deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca Connect is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dim. 9/216:30 amDTW - PTY
2 stops18h 40mMultiple Airlines
ven. 9/263:25 amPTY - DTW
2 stops15h 49mMultiple Airlines
Deal found 9/10$566

Cheapflights Fare Finder

 
Customize your flight search to find flights from Detroit to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated septembre 11, 2025.
Use the filters below to find and compare flights from Detroit Metropolitan Wayne County Airport to Panama City that are best for you.

Fly from

Detroit

Fly to

Panama City

Route

Depart

Return

Price

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

sam. 10/11

6:17 am-4:25 pm

1 stop11h 08m

Panama City Tocumen Intl

sam. 10/18

8:25 am-8:00 pm

1 stop10h 35m

$472

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

sam. 10/25

6:43 am-8:19 pm

1 stop14h 36m

Panama City Tocumen Intl

sam. 11/1

12:03 pm-11:30 pm

1 stop10h 27m

$486

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

ven. 11/14

7:00 am-12:40 am

2 stops17h 40m

Panama City Tocumen Intl

lun. 11/17

2:55 pm-2:09 pm

2 stops23h 14m

$497

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

jeu. 11/13

7:00 am-1:00 am

2 stops18h 00m

Panama City Tocumen Intl

dim. 11/16

2:55 am-6:54 pm

2 stops15h 59m

$503

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

dim. 2/15

8:20 pm-2:00 pm

2 stops17h 40m

Panama City Tocumen Intl

mer. 2/25

2:55 pm-2:09 pm

2 stops23h 14m

$519

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

jeu. 11/13

7:00 am-1:00 am

2 stops18h 00m

Panama City Tocumen Intl

lun. 11/17

2:55 am-6:54 pm

2 stops15h 59m

$540

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

dim. 9/21

6:30 am-12:10 am

2 stops18h 40m

Panama City Tocumen Intl

ven. 9/26

3:25 am-8:14 pm

2 stops15h 49m

$566

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

dim. 9/21

9:12 am-12:10 am

2 stops15h 58m

Panama City Tocumen Intl

sam. 9/27

3:20 am-8:14 pm

2 stops15h 54m

$596

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

ven. 11/7

7:00 am-12:40 am

2 stops17h 40m

Panama City Tocumen Intl

sam. 11/8

2:55 am-6:54 pm

2 stops15h 59m

$613

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

sam. 10/25

7:15 pm-1:00 am

2 stops30h 45m

$185

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/10

Showing 1-10 of 11 results
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Best time to book a flight from Detroit to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Detroit with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Detroit Metropolitan Wayne County Airport to Panama City

How far ahead should I book a flight from Detroit Metropolitan Wayne County Airport to Panama City?

Use this chart to determine the optimal time to book a round-trip flight from Detroit to Panama City. Price data was last updated on August 29, 2025.

The price you pay for your flight from Detroit Metropolitan Wayne County Airport to Panama City may vary depending on when you book. For the best chance of a lower fare, look to book 27 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

What is the cheapest month to book a flight from Detroit Metropolitan Wayne County Airport to Panama City?

Currently, October is the cheapest month in which you can book a flight from Detroit Metropolitan Wayne County Airport to Panama City (average of $478). Flying from Detroit Metropolitan Wayne County Airport to Panama City in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DTW to PTY?

Find hourly flight availability from Detroit to Panama City. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated septembre 11, 2025.

It’s optimal to fly from Detroit Metropolitan Wayne County Airport to Panama City at noon. By choosing this option you can save up to 4% on the cost of your flight, compared to a flight in the morning.

How much does it cost to fly round-trip from Detroit Metropolitan Wayne County Airport to Panama City?

Reviews of airlines servicing Panama City

Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated septembre 11, 2025.
Read reviews from past customers who have flown Delta, United Airlines, and American Airlines from Detroit Metropolitan Wayne County Airport to Panama City. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,960 reviews

Entertainment

7.9

Food

7.3

Boarding

8.2

Comfort

7.9

Overall

8.0

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,960 reviews
Delta
8.0
Very good
7,960 reviews

Entertainment

7.9

Food

7.3

Boarding

8.2

Comfort

7.9

Overall

8.0

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
United Airlines
7.4
Good
8,937 reviews
Delta
8.0
Very good
7,960 reviews

Entertainment

7.9

Food

7.3

Boarding

8.2

Comfort

7.9

Overall

8.0

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,960 reviews

Entertainment

7.9

Food

7.3

Boarding

8.2

Comfort

7.9

Overall

8.0

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from Detroit to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines flying from Detroit Metropolitan Wayne County Airport to Panama City round-trip?

    According to our current data, American Airlines ($578), Delta ($608), and United Airlines ($608) offers the cheapest pricing from Detroit Metropolitan Wayne County Airport to Panama City. These flights start at 34% lower than the current average price 3 months from now.

  • Can I find deals for flights from Detroit to Panama City that include hotel bookings?

    Yes. In addition to deals on Detroit to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Detroit to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Detroit to Panama City.

  • Can I find deals for business class flights from Detroit to Panama City?

    Yes. Cheapflights offers flight deals from Detroit to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Detroit Metropolitan Wayne County Airport to Panama City?

    Currently, October is the cheapest month in which you can book a flight from Detroit Metropolitan Wayne County Airport to Panama City (average of $478). Flying from Detroit Metropolitan Wayne County Airport to Panama City in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Top 3 airlines flying from Detroit to Panama City

Discover the top 3 airlines that operate flights from Detroit to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated septembre 11, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$578Average$781FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$608Average$855FlexibilityNo cancel feeOn-time69%
DeltaCheapest$608Average$918FlexibilityNo cancel feeOn-timeN/A

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