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Panama City

$178+ Cheap flights from Detroit Metropolitan Wayne County Airport (DTW) to Panama City (PTY)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/19. Fares are subject to change and may not be available on all flights or dates of travel.
DTW — PTY
Feb 26 — Mar 51
Thu 2/26
Thu 3/5
1 adult, Economy
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Cheap flight deals from Detroit to Panama City

Cheapest flights from Detroit to Panama City
Explore the most affordable flight options available from Detroit to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 27, 2026.

This Avianca Connect deal was found by Cheapflights users on 1/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca Connect is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/1912:22 pm
DTW
-
PTY
2 stops13h 38m
Multiple Airlines
Mon 3/232:55 am
PTY
-
DTW
2 stops15h 51m
Multiple Airlines
Deal found 1/25$458
This Avianca Connect deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca Connect is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/124:50 pm
DTW
-
PTY
2 stops17h 00m
Multiple Airlines
Mon 3/162:55 am
PTY
-
DTW
2 stops15h 51m
Multiple Airlines
Deal found 1/26$459
This Avianca Connect deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca Connect is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/1212:22 pm
DTW
-
PTY
2 stops13h 38m
Multiple Airlines
Thu 3/199:45 am
PTY
-
DTW
2 stops13h 14m
Multiple Airlines
Deal found 1/26$474
This Avianca Connect deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca Connect is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/164:50 pm
DTW
-
PTY
2 stops17h 00m
Multiple Airlines
Thu 3/199:45 am
PTY
-
DTW
2 stops13h 14m
Multiple Airlines
Deal found 1/26$475
This Mytrip deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/35:09 am
DTW
-
PTY
3 stops27h 41m
Multiple Airlines
Wed 3/411:25 am
PTY
-
DTW
3 stops23h 36m
Multiple Airlines
Deal found 1/26$479
This Mytrip deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/285:00 am
DTW
-
PTY
2 stops27h 50m
Multiple Airlines
Tue 2/32:55 am
PTY
-
DTW
2 stops21h 24m
Multiple Airlines
Deal found 1/27$480
This Avianca Connect deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca Connect is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/48:49 am
DTW
-
PTY
2 stops15h 51m
Multiple Airlines
Tue 3/319:55 am
PTY
-
DTW
2 stops13h 04m
Multiple Airlines
Deal found 1/26$482
This Avianca Connect deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca Connect is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/45:45 am
DTW
-
PTY
2 stops18h 55m
Multiple Airlines
Wed 3/112:55 am
PTY
-
DTW
2 stops15h 51m
Multiple Airlines
Deal found 1/27$485
This Avianca Connect deal was found by Cheapflights users on 1/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca Connect is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/217:17 am
DTW
-
PTY
2 stops17h 43m
Multiple Airlines
Thu 2/262:55 am
PTY
-
DTW
2 stops21h 04m
Multiple Airlines
Deal found 1/25$497

Find flight deals from Detroit to Panama City

Discover tips and strategies to find the most affordable flight options for your journey from Detroit (DTW) to Panama City (PTY). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated January 27, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$458
(Avianca Connect)

One-way from

$178
(Kiwi.com)

Popular in

February

Cheapest in

June

Average price

$773
Provider with most accurate pricing for Detroit Metropolitan Wayne County-Panama City Tocumen Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Detroit Metropolitan Wayne County-Panama City Tocumen Intl flights.
Search Deals
From Detroit Metropolitan Wayne County to Panama City Tocumen Intl
Search Deals
One-way flight from Detroit Metropolitan Wayne County to Panama City Tocumen Intl
Search Deals
Highest demand for flights based on searches. 6% potential increase in price ($56 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($13 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in January 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Detroit to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 27, 2026.
Use the filters below to find and compare flights from Detroit Metropolitan Wayne County Airport to Panama City that are best for you.

Fly from

Detroit

Fly to

Panama City

Route

Depart

Return

Price

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Thu 3/19

12:22 pm-1:00 am

2 stops13h 38m

Panama City Tocumen Intl

Mon 3/23

2:55 am-7:46 pm

2 stops15h 51m

$458

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Thu 3/12

4:50 pm-8:50 am

2 stops17h 00m

Panama City Tocumen Intl

Mon 3/16

2:55 am-7:46 pm

2 stops15h 51m

$459

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Wed 3/4

8:49 am-12:40 am

2 stops15h 51m

Panama City Tocumen Intl

Tue 3/31

9:55 am-11:59 pm

2 stops13h 04m

$482

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Wed 3/11

8:49 am-12:40 am

2 stops16h 51m

Panama City Tocumen Intl

Wed 3/18

9:45 am-11:59 pm

2 stops13h 14m

$485

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Sat 2/21

7:17 am-1:00 am

2 stops17h 43m

Panama City Tocumen Intl

Thu 2/26

2:55 am-11:59 pm

2 stops21h 04m

$497

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Tue 2/24

5:45 am-1:00 am

2 stops19h 15m

Panama City Tocumen Intl

Mon 3/2

2:55 am-9:00 pm

2 stops18h 05m

$512

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Fri 5/8

8:00 am-12:45 am

2 stops17h 45m

Panama City Tocumen Intl

Fri 5/8

3:25 am-11:59 pm

2 stops19h 34m

$533

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Fri 4/17

5:00 am-9:10 pm

2 stops17h 10m

Panama City Tocumen Intl

Fri 4/24

3:25 am-9:34 pm

2 stops17h 09m

$533

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Thu 2/12

5:45 am-1:00 am

2 stops19h 15m

Panama City Tocumen Intl

Mon 3/2

2:55 am-9:39 pm

2 stops18h 44m

$597

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Thu 2/19

10:59 pm-8:50 am

3 stops57h 51m

$178

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/25

Showing 1-10 of 15 results
1
2

Compare providers for flights from Detroit to Panama City

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Detroit to Panama City in January.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars
AranGrantPrice Accuracy2 starsTrust Score*2 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Detroit Metropolitan Wayne County Airport-Panama City flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Detroit Metropolitan Wayne County Airport-Panama City flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Detroit Metropolitan Wayne County Airport-Panama City flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Detroit Metropolitan Wayne County Airport-Panama City flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Detroit Metropolitan Wayne County Airport-Panama City flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Detroit to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Detroit with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Detroit Metropolitan Wayne County Airport to Panama City

What is the cheapest month to book a flight from Detroit Metropolitan Wayne County Airport to Panama City?

Currently, June is the cheapest month in which you can book a flight from Detroit Metropolitan Wayne County Airport to Panama City (average of $592). Flying from Detroit Metropolitan Wayne County Airport to Panama City in February is currently the most expensive (average of $811). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Panama City

Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated January 27, 2026.
Read reviews from past customers who have flown Delta, United Airlines, and American Airlines from Detroit Metropolitan Wayne County Airport to Panama City. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,119 reviews

Crew

8.5

Comfort

7.9

Entertainment

7.8

Overall

7.9

Boarding

8.1

Food

7.2

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,119 reviews
Delta
7.9
Good
8,119 reviews

Crew

8.5

Comfort

7.9

Entertainment

7.8

Overall

7.9

Boarding

8.1

Food

7.2

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
United Airlines
7.4
Good
9,205 reviews
Delta
7.9
Good
8,119 reviews

Crew

8.5

Comfort

7.9

Entertainment

7.8

Overall

7.9

Boarding

8.1

Food

7.2

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,197 reviews
Delta
7.9
Good
8,119 reviews

Crew

8.5

Comfort

7.9

Entertainment

7.8

Overall

7.9

Boarding

8.1

Food

7.2

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Detroit to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines flying from Detroit Metropolitan Wayne County Airport to Panama City round-trip?

    According to our current data, American Airlines ($578), Delta ($608), and United Airlines ($608) offers the cheapest pricing from Detroit Metropolitan Wayne County Airport to Panama City. These flights start at 27% lower than the current average price 3 months from now.

  • Can I find deals for flights from Detroit to Panama City that include hotel bookings?

    Yes. In addition to deals on Detroit to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Detroit to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Detroit to Panama City.

  • Can I find deals for business class flights from Detroit to Panama City?

    Yes. Cheapflights offers flight deals from Detroit to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Detroit Metropolitan Wayne County Airport to Panama City?

    Currently, June is the cheapest month in which you can book a flight from Detroit Metropolitan Wayne County Airport to Panama City (average of $592). Flying from Detroit Metropolitan Wayne County Airport to Panama City in February is currently the most expensive (average of $811). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Top 3 airlines flying from Detroit to Panama City

Discover the top 3 airlines that operate flights from Detroit to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 27, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$578Average$816FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$608Average$811FlexibilityNo cancel feeOn-time69%
DeltaCheapest$608Average$934FlexibilityNo cancel feeOn-timeN/A

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