HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Panama City

$221+ Cheap flights from Detroit Metropolitan Wayne County Airport (DTW) to Panama City (PTY)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/16. Fares are subject to change and may not be available on all flights or dates of travel.
DTW — PTY
Jan 11 — Jan 181
Sun 1/11
Sun 1/18
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Detroit to Panama City with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Detroit to Panama City

Cheapest flights from Detroit to Panama City
Explore the most affordable flight options available from Detroit to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 12, 2025.

This Kiwi.com deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/144:39 pmDTW - PTY
1 stop15h 27mMultiple Airlines
Tue 1/202:55 amPTY - DTW
2 stops34h 16mMultiple Airlines
Deal found 12/10$741
This United Airlines deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/316:00 amDTW - PTY
1 stop8h 45mUnited Airlines
Thu 1/84:41 pmPTY - DTW
2 stops17h 29mUnited Airlines
Deal found 12/10$758
This Kiwi.com deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/114:39 pmDTW - PTY
1 stop15h 27mMultiple Airlines
Fri 12/1211:25 amPTY - DTW
2 stops12h 54mMultiple Airlines
Deal found 12/11$766
This Kiwi.com deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/144:39 pmDTW - PTY
1 stop15h 27mMultiple Airlines
Tue 12/169:45 amPTY - DTW
2 stops21h 59mMultiple Airlines
Deal found 12/11$774
This Avianca Connect deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca Connect is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/286:15 amDTW - PTY
2 stops18h 45mMultiple Airlines
Sun 1/182:55 amPTY - DTW
2 stops19h 17mMultiple Airlines
Deal found 12/10$804
This Avianca Connect deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca Connect is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/136:15 amDTW - PTY
2 stops18h 45mMultiple Airlines
Mon 12/152:55 amPTY - DTW
2 stops18h 09mMultiple Airlines
Deal found 12/11$813
This Kiwi.com deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/144:39 pmDTW - PTY
1 stop26h 41mMultiple Airlines
Wed 12/177:25 pmPTY - DTW
2 stops36h 17mMultiple Airlines
Deal found 12/11$830

Find flight deals from Detroit to Panama City

Discover tips and strategies to find the most affordable flight options for your journey from Detroit (DTW) to Panama City (PTY). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated December 12, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$483
(Avianca Connect)

One-way from

$221
(Kiwi.com)

Popular in

August

Cheapest in

June

Average price

$949
Provider with most accurate pricing for Detroit Metropolitan Wayne County-Panama City Tocumen Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Detroit Metropolitan Wayne County-Panama City Tocumen Intl flights.
Search Deals
From Detroit Metropolitan Wayne County to Panama City Tocumen Intl
Search Deals
One-way flight from Detroit Metropolitan Wayne County to Panama City Tocumen Intl
Search Deals
Highest demand for flights based on searches. 5% potential increase in price ($47 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($18 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Detroit to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 12, 2025.
Use the filters below to find and compare flights from Detroit Metropolitan Wayne County Airport to Panama City that are best for you.

Fly from

Detroit

Fly to

Panama City

Route

Depart

Return

Price

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Tue 2/10

6:35 am-1:00 am

2 stops18h 25m

Panama City Tocumen Intl

Mon 2/23

2:55 am-9:41 pm

2 stops18h 46m

$483

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Thu 1/22

5:15 am-1:00 am

2 stops19h 45m

Panama City Tocumen Intl

Thu 1/29

9:45 am-10:12 pm

2 stops12h 27m

$495

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Sun 2/8

6:35 am-1:00 am

2 stops18h 25m

Panama City Tocumen Intl

Thu 2/12

2:55 pm-9:11 am

2 stops18h 16m

$511

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Mon 1/26

7:00 am-12:40 am

2 stops17h 40m

Panama City Tocumen Intl

Sun 2/1

2:55 am-11:59 pm

2 stops21h 04m

$515

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Mon 1/19

6:35 am-12:40 am

2 stops18h 05m

Panama City Tocumen Intl

Mon 2/9

2:55 am-10:44 pm

2 stops19h 49m

$530

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Thu 1/22

5:30 am-1:00 am

2 stops19h 30m

Panama City Tocumen Intl

Mon 1/26

2:55 am-10:44 pm

2 stops19h 49m

$536

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Sat 1/24

11:00 am-8:34 pm

1 stop9h 34m

Panama City Tocumen Intl

Tue 2/3

5:50 pm-10:12 pm

2 stops28h 22m

$546

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Fri 1/23

5:15 am-12:40 am

2 stops19h 25m

Panama City Tocumen Intl

Fri 1/30

2:55 am-11:59 pm

2 stops21h 04m

$547

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Sat 2/7

6:35 am-1:00 am

2 stops18h 25m

Panama City Tocumen Intl

Thu 2/12

2:55 am-9:41 pm

2 stops18h 46m

$547

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Fri 1/23

5:15 am-12:40 am

2 stops19h 25m

Panama City Tocumen Intl

Sun 2/1

2:55 am-11:59 pm

2 stops21h 04m

$573

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/10

Showing 1-10 of 14 results
1
2

Compare providers for flights from Detroit to Panama City

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Detroit to Panama City in December.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
eDreamsPrice Accuracy3 starsTrust Score*3 stars
AranGrantPrice Accuracy2 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Detroit Metropolitan Wayne County Airport-Panama City flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Detroit Metropolitan Wayne County Airport-Panama City flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Detroit Metropolitan Wayne County Airport-Panama City flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Detroit Metropolitan Wayne County Airport-Panama City flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Detroit Metropolitan Wayne County Airport-Panama City flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Detroit to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Detroit with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Detroit Metropolitan Wayne County Airport to Panama City

What is the cheapest month to book a flight from Detroit Metropolitan Wayne County Airport to Panama City?

Currently, June is the cheapest month in which you can book a flight from Detroit Metropolitan Wayne County Airport to Panama City (average of $592). Flying from Detroit Metropolitan Wayne County Airport to Panama City in February is currently the most expensive (average of $759). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DTW to PTY?

Find hourly flight availability from Detroit to Panama City. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 12, 2025.

It’s optimal to fly from Detroit Metropolitan Wayne County Airport to Panama City in the evening. By choosing this option you can save up to 71% on the cost of your flight, compared to a flight in the afternoon.

How much does it cost to fly round-trip from Detroit Metropolitan Wayne County Airport to Panama City?

Reviews of airlines servicing Panama City

Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated December 12, 2025.
Read reviews from past customers who have flown Delta, United Airlines, and American Airlines from Detroit Metropolitan Wayne County Airport to Panama City. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,007 reviews

Boarding

8.1

Overall

7.9

Comfort

7.9

Crew

8.5

Food

7.3

Entertainment

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,007 reviews
Delta
7.9
Good
8,007 reviews

Boarding

8.1

Overall

7.9

Comfort

7.9

Crew

8.5

Food

7.3

Entertainment

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
United Airlines
7.4
Good
9,095 reviews
Delta
7.9
Good
8,007 reviews

Boarding

8.1

Overall

7.9

Comfort

7.9

Crew

8.5

Food

7.3

Entertainment

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,050 reviews
Delta
7.9
Good
8,007 reviews

Boarding

8.1

Overall

7.9

Comfort

7.9

Crew

8.5

Food

7.3

Entertainment

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Detroit to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines flying from Detroit Metropolitan Wayne County Airport to Panama City round-trip?

    According to our current data, American Airlines ($578), Delta ($608), and United Airlines ($608) offers the cheapest pricing from Detroit Metropolitan Wayne County Airport to Panama City. These flights start at 30% lower than the current average price 3 months from now.

  • Can I find deals for flights from Detroit to Panama City that include hotel bookings?

    Yes. In addition to deals on Detroit to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Detroit to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Detroit to Panama City.

  • Can I find deals for business class flights from Detroit to Panama City?

    Yes. Cheapflights offers flight deals from Detroit to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Detroit Metropolitan Wayne County Airport to Panama City?

    Currently, June is the cheapest month in which you can book a flight from Detroit Metropolitan Wayne County Airport to Panama City (average of $592). Flying from Detroit Metropolitan Wayne County Airport to Panama City in February is currently the most expensive (average of $759). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Top 3 airlines flying from Detroit to Panama City

Discover the top 3 airlines that operate flights from Detroit to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 12, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$578Average$799FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$608Average$809FlexibilityNo cancel feeOn-time69%
DeltaCheapest$608Average$949FlexibilityNo cancel feeOn-timeN/A

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.