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$178+ Cheap flights from Detroit Metropolitan Wayne County Airport (DTW) to Panama City (PTY)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/9. Fares are subject to change and may not be available on all flights or dates of travel.
DTW — PTY
Aug 4 — Aug 111
Mon 8/4
Mon 8/11
1 adult, Economy
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Cheapflights Tip: The best prices from Detroit Metropolitan Wayne County to Panama City Tocumen Intl are usually found in April or June, booked 63 days in advance, depart on a Wednesday or Monday and return on a Monday

Cheap flight deals from Detroit to Panama City

Discover tips and strategies to find the most affordable flight options for your journey from Detroit (DTW) to Panama City (PTY). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated July 30, 2025.

Round-trip from

$427
(Avianca Connect)

One-way from

$190
(Kiwi.com)

Popular in

December

Cheapest in

April

Average price

$891
From Detroit Metropolitan Wayne County to Panama City Tocumen Intl
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One-way flight from Detroit Metropolitan Wayne County to Panama City Tocumen Intl
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Highest demand for flights based on searches. 9% potential increase in price ($95 potential increase over avg. RT price).
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Cheapest flight prices on average. 5% potential price decrease ($42 potential savings vs. average RT price).
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Average for round-trip flights in July 2025
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Find flight deals from Detroit to Panama City

Cheapest flights from Detroit to Panama City
Explore the most affordable flight options available from Detroit to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 30, 2025.

This Avianca Connect deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca Connect is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/116:41 amDTW - PTY
2 stops15h 29mMultiple Airlines
Wed 9/173:20 amPTY - DTW
2 stops19h 23mMultiple Airlines
Deal found 7/28$416
This Delta deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/199:15 pmDTW - PTY
1 stop16h 41mDelta
Wed 10/292:21 pmPTY - DTW
1 stop18h 04mDelta
Deal found 7/28$491
This United Airlines deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/217:00 amDTW - PTY
2 stops12h 37mUnited Airlines
Tue 10/283:41 pmPTY - DTW
2 stops17h 04mUnited Airlines
Deal found 7/28$496

Cheapflights Fare Finder

 
Customize your flight search to find flights from Detroit to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 30, 2025.
Use the filters below to find and compare flights from Detroit Metropolitan Wayne County Airport to Panama City that are best for you.

Fly from

Detroit

Fly to

Panama City

Route

Depart

Return

Price

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Sun 10/19

6:41 am-9:10 pm

2 stops15h 29m

Panama City Tocumen Intl

Sun 10/26

3:19 am-11:29 pm

2 stops19h 10m

$427

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Sun 10/19

9:15 pm-12:56 pm

1 stop16h 41m

Panama City Tocumen Intl

Wed 10/29

2:21 pm-9:25 am

1 stop18h 04m

$491

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Tue 10/21

7:00 am-6:37 pm

2 stops12h 37m

Panama City Tocumen Intl

Tue 10/28

3:41 pm-9:45 am

2 stops17h 04m

$496

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Tue 9/9

6:41 am-12:10 am

2 stops18h 29m

$178

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/28

Best time to book a flight from Detroit to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Detroit with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Detroit Metropolitan Wayne County Airport to Panama City

How far ahead should I book a flight from Detroit Metropolitan Wayne County Airport to Panama City?

Use this chart to determine the optimal time to book a round-trip flight from Detroit to Panama City. Price data was last updated on July 25, 2025.

The price you pay for your flight from Detroit Metropolitan Wayne County Airport to Panama City may vary depending on when you book. For the best chance of a lower fare, look to book 62 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

What is the cheapest month to book a flight from Detroit Metropolitan Wayne County Airport to Panama City?

Currently, October is the cheapest month in which you can book a flight from Detroit Metropolitan Wayne County Airport to Panama City (average of $478). Flying from Detroit Metropolitan Wayne County Airport to Panama City in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DTW to PTY?

Find hourly flight availability from Detroit to Panama City. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated July 30, 2025.

It’s optimal to fly from Detroit Metropolitan Wayne County Airport to Panama City at noon. By choosing this option you can save up to 4% on the cost of your flight, compared to a flight in the morning.

Reviews of airlines servicing Panama City

Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated July 30, 2025.
Read reviews from past customers who have flown Delta and United Airlines from Detroit Metropolitan Wayne County Airport to Panama City. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,980 reviews

Entertainment

7.9

Boarding

8.2

Overall

8.0

Food

7.3

Comfort

7.9

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,980 reviews
Delta
8.0
Very good
7,980 reviews

Entertainment

7.9

Boarding

8.2

Overall

8.0

Food

7.3

Comfort

7.9

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
United Airlines
7.4
Good
8,896 reviews
Delta
8.0
Very good
7,980 reviews

Entertainment

7.9

Boarding

8.2

Overall

8.0

Food

7.3

Comfort

7.9

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from Detroit to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines flying from Detroit Metropolitan Wayne County Airport to Panama City round-trip?

    According to our current data, Delta ($491), and United Airlines ($496) offers the cheapest pricing from Detroit Metropolitan Wayne County Airport to Panama City. These flights start at 42% lower than the current average price 3 months from now.

  • Can I find deals for flights from Detroit to Panama City that include hotel bookings?

    Yes. In addition to deals on Detroit to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Detroit to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Detroit to Panama City.

  • Can I find deals for business class flights from Detroit to Panama City?

    Yes. Cheapflights offers flight deals from Detroit to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Detroit Metropolitan Wayne County Airport to Panama City?

    Currently, October is the cheapest month in which you can book a flight from Detroit Metropolitan Wayne County Airport to Panama City (average of $478). Flying from Detroit Metropolitan Wayne County Airport to Panama City in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 3 airlines flying from Detroit to Panama City

Discover the top 3 airlines that operate flights from Detroit to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 30, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$608Average$839FlexibilityNo cancel feeOn-time69%
DeltaCheapest$608Average$865FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$628Average$800FlexibilityNo cancel feeOn-time71%

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